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1

Grazul-Bilska, Anna T., Pawel P. Borowicz, Mary Lynn Johnson, et al. "Placental development during early pregnancy in sheep: vascular growth and expression of angiogenic factors in maternal placenta." REPRODUCTION 140, no. 1 (2010): 165–74. http://dx.doi.org/10.1530/rep-09-0548.

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Placental vascular development (angiogenesis) is critical for placental function and thus for normal embryonic/fetal growth and development. Specific environmental factors or use of assisted reproductive techniques may result in poor placental angiogenesis, which may contribute to embryonic losses and/or fetal growth retardation. Uterine tissues were collected on days 14, 16, 18, 20, 22, 24, 26, 28, and 30 after mating and on day 10 after estrus (nonpregnant controls) to determine vascular development and expression of several factors involved in the regulation of angiogenesis in the endometri
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DeShazo, Emily K., Zully E. Contreras-Correa, Robin Sessums, Thomas H. Duncan, and Caleb Lemley. "PSI-13 Effects of maternal nutrient restriction and melatonin supplementation on fetal mammary gland vascularity." Journal of Animal Science 99, Supplement_3 (2021): 277–78. http://dx.doi.org/10.1093/jas/skab235.509.

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Abstract The objective was to determine fetal mammary gland vascularity following dietary melatonin supplementation in late pregnant nutrient restricted Brangus heifers carrying female fetuses from two different seasons (spring calving, n = 12; fall calving, n = 13). Heifers were assigned one of four nutritional treatments at day 160 of gestation; adequate fed (ADQ-CON; 100% NRC; n = 6), nutrient restricted (RES-CON; 60% NRC; n = 6), adequate fed with 20 mg of melatonin (ADQ-MEL; n = 6), and nutrient restricted with 20 mg of melatonin (RES-MEL; n = 7). Fetal mammary glands were collected at da
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3

Srinivasan, Anu Priyadharshini, B. O. Parijatham Omprakash, Kandhimalla Lavanya, Priyadharshini Subbulakshmi Murugesan, and Saraswathi Kandaswamy. "A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies." Journal of Pregnancy 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/193925.

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The vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way. In this study, we attempted to identify villous vascular changes in a group of term placentae from mothers with diseases complicating pregnancy. Chorangiosis was the most frequently identified lesion while chorangioma was found in only 2 cases. There were no cases of chorangiomatosis. A few cases had normal villous vasculature. Maternal diseases ha
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4

S.M. Ibrahim M.Sc., Marwa, Azza M.A. Said M.D, Islam A.M. Soliman M.D., and Mahmoud A. El Samkary M.D. "OBSERVATION OF CENTRAL MACULAR THICKNESS AND MICROVASCULATURE BY OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN AN AMBLYOPIC PATIENT." International Journal of Advanced Research 11, no. 02 (2023): 678–84. http://dx.doi.org/10.21474/ijar01/16298.

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Purpose: Documented the macular area changes regarding thickness and vascularity on an amblyopic patient by optical coherence tomography and optical coherence tomography angiograph. Patients and methods: A case control observational study. AllPatients were attended to Ain shams university clinic and the clinic of Ophthalmology Department of Re- search Institute of Ophthalmology in period between October 2020 to May 2021.the study included 40 patients, age between 7-18y, with unilateral amblyopic eye and divided into 4 groups each group 10 patients, unilateral amblyopic with strabismus, anisome
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5

Vongsavan, N., and B. Matthews. "The Vascularity of Dental Pulp in Cats." Journal of Dental Research 71, no. 12 (1992): 1913–15. http://dx.doi.org/10.1177/00220345920710121101.

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The fraction of the volume of the coronal pulp of cat canines that is occupied by blood vessels was estimated by measurement of the cross-sectional areas of all the vessels in a complete transverse section of the pulp from each of four teeth. The sections were taken 0.5 mm from the pulp comu. Overall, 14.4% of the area of the pulp was occupied by vessels. In the core of the pulp, the average value was 42.9%, and superficially, near the odontoblast layer, it was between 5 and 10%. The average capillary density was 1402 /mm2, which is higher than in most other tissues. Laser Doppler flow meters
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6

Farha, Samar, Kewal Asosingh, Daniel Laskowski, et al. "Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle." Journal of Applied Physiology 103, no. 5 (2007): 1789–95. http://dx.doi.org/10.1152/japplphysiol.00614.2007.

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Gas transfer in the female lung varies over the menstrual cycle in parallel with the cyclic angiogenesis that occurs in the uterine endometrium. Given that vessels form and regress in the uterus under the control of hormones, angiogenic factors, and proangiogenic circulating bone marrow-derived progenitor cells, we tested the possibility that variation in pulmonary gas transfer over the menstrual cycle is related to a systemic cyclic proangiogenic state that influences lung vascularity. Women were evaluated over the menstrual cycle with weekly measures of lung diffusing capacity and its compon
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7

Mignemi, Nicholas, Heather Cole, Masato Yausa, David Gailani, Jay L. Degen, and Jonathan G. Schoenecker. "Deficiency in Plasminogen Cause Decreased Vascularity in Sold Tissue Organs and Bone." Blood 118, no. 21 (2011): 857. http://dx.doi.org/10.1182/blood.v118.21.857.857.

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Abstract Abstract 857 A sufficient vascular supply is critical for proper physiologic function of solid-tissue organs and bone. Tissue vascularity is mediated concomitantly through vascular patency and angiogenesis. Recently, numerous studies have associated plasminogen, the key fibrinolytic protease of the coagulation system, with maintaining vascular patency by preventing fibrin accumulation with in the vasculature. Additionally, plasminogen may also have a direct role in angiogenesis as it has been shown in vitro that inhibitors of plasmin(ogen) suppress formation of capillary structures fr
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8

Gupta, Dharmendra Kumar, Samvartika Somavanshi, Arti Agrawal, Rajni Bharti, and Neetu Shree. "Capillary Hemangioma of the Lateral Nasal Wall: An Unusual Location." An International Journal Clinical Rhinology 5, no. 3 (2012): 127–29. http://dx.doi.org/10.5005/jp-journals-10013-1133.

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ABSTRACT Capillary hemangioma also known as lobular capillary hemangioma (LCH) or pyogenic granuloma is a benign, vascular lesion of unknown origin, composed of blood vessels and are probably developmental rather than neoplastic in origin. They usually affect skin and mucous membranes of the oral cavity and rarely nasal mucosa. LCH bleeds on manipulations due to high vascularity. Microtraumas and hormonal imbalance are the major etiological factors in its development. Total excisional surgery is sufficient for treatment of the LCH. Capillary hemangioma arising from the nasal cavity is rarely e
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9

Lois, J. F., H. J. Fischer, J. M. Mirra, and A. S. Gomes. "Angiography of Histopathologic Variants of Synovial Sarcoma." Acta Radiologica. Diagnosis 27, no. 4 (1986): 449–54. http://dx.doi.org/10.1177/028418518602700416.

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Synovial sarcomas are rare soft tissue tumors which histopathologically can be divided into monophasic, biphasic and mixed variants. As part of a protocol for intra-arterial chemotherapy 12 patients with biopsy proven synovial sarcoma underwent angiography. The angiograms on these patients were reviewed to determine whether synovial sarcomas and their variants demonstrated a characteristic angiographic appearance. Synovial sarcomas appeared angiographically as soft tissue masses which showed a fine network of tumor vessels with an inhomogeneous capillary blush. Their degree of vascularity vari
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10

Viboolvorakul, Sheepsumon, Hideyuki Niimi, Natchaya Wongeak-in, Sukanya Eksakulkla, and Suthiluk Patumraj. "Increased capillary vascularity in the femur of aged rats by exercise training." Microvascular Research 78, no. 3 (2009): 459–63. http://dx.doi.org/10.1016/j.mvr.2009.07.003.

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11

Asghar, Adil, Ashutosh Kumar, Ravi Narayan, and Shagufta Naaz. "Is the cortical capillary renamed as the transcortical vessel in diaphyseal vascularity?" Anatomical Record 303, no. 11 (2020): 2774–84. http://dx.doi.org/10.1002/ar.24461.

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Tomanek, R. J., P. A. Barlow, P. M. Connell, Y. Chen, and R. J. Torry. "Effects of hypothyroidism and hypertension on myocardial perfusion and vascularity in rabbits." American Journal of Physiology-Heart and Circulatory Physiology 265, no. 5 (1993): H1638—H1644. http://dx.doi.org/10.1152/ajpheart.1993.265.5.h1638.

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We considered the role of thyroid hormones in the growth of the coronary microvasculature during various levels of afterload. Arterial pressure was increased for 3 mo in hypothyroid and euthyroid rabbits via the Page (1-kidney, 1-wrap) method. Systolic pressures (mmHg +/- SE) indicated that the groups could be characterized as follows: euthyroid sham normotensive (103 +/- 5), euthyroid Page hypertensive (158 +/- 24), hypothyroid Page normotensive (110 +/- 5), and hypothyroid sham hypotensive (87 +/- 5). The hypothyroid groups were characterized by bradycardia. Left ventricular weight-to-body w
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13

Capece, Marco, Daniela Montorio, Chiara Comune, et al. "Retinal and Optic Disc Vascular Changes in Patients Using Long-Term Tadalafil: A Prospective Non-Randomized Matched-Pair Study." Diagnostics 11, no. 5 (2021): 802. http://dx.doi.org/10.3390/diagnostics11050802.

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Retinal, choroidal and optic disc vascularity has never been evaluated in patients taking PDE5is long-term. The aim of our study was to evaluate the neurostructural and vascular changes after long-term use of tadalafil, using spectral domain (SD)-optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). In the present clinical trial, 27 patients who have been taking tadalafil 20 mg on alternate days (OAD) for at least 6 months (Group A) were enrolled. The matched group consisted of 27 healthy men (Group B). Both groups of patients underwent SD-OCT to study ganglio
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14

Majeed, A. F., M. S. Shalal, and T. R. Mohammed. "Histology of ovine placenta during gestation periods." Kufa Journal For Veterinary Medical Sciences 2, no. 1 (2011): 163–73. http://dx.doi.org/10.36326/kjvs/2011/v2i14033.

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Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the centers of the sampled placentomes .Immediately following collection ,the samples were fixed in 10% bufferd neutral formalin for 24 h .Tissue specimens were dehydrated in a graded series of alcohol , cleared by xylol and embded in paraffin .Histologic section were cut at 3-4 µm thickness ,Stained with hematoxylin and eosin(H&E) (6).The period
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15

Shalal, M. S., T. R. Mohammed, and A. F. Majeed. "Histology of ovine placenta during gestation periods." Kufa Journal For Veterinary Medical Sciences 3, no. 1 (2012): 138–47. http://dx.doi.org/10.36326/kjvs/2012/v3i14073.

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Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the centers of the sampled placentomes .Immediately following collection ,the samples were fixed in 10% bufferd neutral formalin for 24 h .Tissue specimens were dehydrated in a graded series of alcohol , cleared by xylol and embded in paraffin .Histologic section were cut at 3-4 µm thickness ,Stained with hematoxylin and eosin(H&E) (6).The period
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16

Majeed, A. F., M. S. Shalal, and T. R. Mohammed. "Histology of ovine placenta during gestation periods." Kufa Journal For Veterinary Medical Sciences 2, no. 1 (2011): 163–73. http://dx.doi.org/10.36326/kjvs/2011/v2i14033.

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Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the centers of the sampled placentomes .Immediately following collection ,the samples were fixed in 10% bufferd neutral formalin for 24 h .Tissue specimens were dehydrated in a graded series of alcohol , cleared by xylol and embded in paraffin .Histologic section were cut at 3-4 µm thickness ,Stained with hematoxylin and eosin(H&E) (6).The period
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17

Shalal, M. S., T. R. Mohammed, and A. F. Majeed. "Histology of ovine placenta during gestation periods." Kufa Journal For Veterinary Medical Sciences 3, no. 1 (2012): 138–47. http://dx.doi.org/10.36326/kjvs/2012/v3i14073.

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Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the centers of the sampled placentomes .Immediately following collection ,the samples were fixed in 10% bufferd neutral formalin for 24 h .Tissue specimens were dehydrated in a graded series of alcohol , cleared by xylol and embded in paraffin .Histologic section were cut at 3-4 µm thickness ,Stained with hematoxylin and eosin(H&E) (6).The period
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18

Nabil, M., P. Decuzzi, and P. Zunino. "Modelling mass and heat transfer in nano-based cancer hyperthermia." Royal Society Open Science 2, no. 10 (2015): 150447. http://dx.doi.org/10.1098/rsos.150447.

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We derive a sophisticated mathematical model for coupled heat and mass transport in the tumour microenvironment and we apply it to study nanoparticle delivery and hyperthermic treatment of cancer. The model has the unique ability of combining the following features: (i) realistic vasculature; (ii) coupled capillary and interstitial flow; (iii) coupled capillary and interstitial mass transfer applied to nanoparticles; and (iv) coupled capillary and interstitial heat transfer, which are the fundamental mechanisms governing nano-based hyperthermic treatment. This is an improvement with respect to
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19

Luciano, Mark G., David J. Skarupa, Amy M. Booth, Arcangela S. Wood, Christine L. Brant, and Martha J. Gdowski. "Cerebrovascular Adaptation in Chronic Hydrocephalus." Journal of Cerebral Blood Flow & Metabolism 21, no. 3 (2001): 285–94. http://dx.doi.org/10.1097/00004647-200103000-00012.

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This study characterizes the regional changes in vascularity, which accompanies chronic progressive hydrocephalus. Fifteen dogs underwent surgical induction of hydrocephalus and were used for histologic studies. Animals were divided into 4 groups: surgical control, short term (≤5 weeks), intermediate term ((8 weeks), and long term (10 to 12 weeks). Vessel diameter, density, and luminal area were calculated by imaging quantification after manual vessel identification in the cortical gray, white matter, and caudate nucleus. Capillary vessel diameter decreased 23.5% to 30.2% ( P < 0.01) in the
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20

Magera, Lukáš, Jan Krásný, Patrik Pluhovský, and Lucie Holubová. "Changes of the Foveal Avascular Zone and Macular Microvasculature within the Framework of OCT Angiography Examination in Young Patients with Type 1 Diabetes (Pilot Study)." Czech and Slovak Ophthalmology 76, no. 3 (2020): 111–17. http://dx.doi.org/10.31348/2020/19.

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Aim: Learn about the development and changes in foveal avascular zone (FAZ) and vascularity of retina in the surrounding zone, depending on the duration in young diabetic patients type 1 (T1DM). Methods: As part of regular one-year examinations of young T1DM patients at the Eye Clinic of the University Hospital Královské Vinohrady in Prague (Czech Republic, EU) from January to December 2019, OCT angiography using the device Spectralis (Heidelberg Engineering) was included. Forty patients aged 18 to 30 years were examined, median 21 years. T1DM was diagnosed in childhood and lasted for more tha
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Marla, Vinay, Ashish Shrestha, Khushboo Goel, and Sajeev Shrestha. "The Histopathological Spectrum of Pyogenic Granuloma: A Case Series." Case Reports in Dentistry 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/1323798.

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Background.Pyogenic granuloma is a reactive tumor-like lesion commonly affecting the oral cavity. These lesions usually appear as localized solitary nodule with a sessile or pedunculated base and colour varying from red, purplish, or pink, depending on the vascularity of the lesion. Pyogenic granuloma shows predilection for gingiva and is usually slow growing, but at times it shows rapid growth. The natural course of this lesion can be categorized into three distinct phases, namely, (i) cellular phase, (ii) capillary phase/vascular phase, and (iii) involutionary phase. Histopathologically, pyo
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22

Oh, Jaeryung, Daniel Jinhag Baik, and Jaemoon Ahn. "Inter-relationship between retinal and choroidal vasculatures using optical coherence tomography angiography in normal eyes." European Journal of Ophthalmology 30, no. 1 (2018): 48–57. http://dx.doi.org/10.1177/1120672118816225.

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Purpose: To quantify vascular and structural macular variables in healthy eyes and to investigate correlations between these variables and age using optical coherence tomography angiography. Materials and methods: A total of 261 eyes of 261 subjects with normal fundus were included. Central macular thickness, ganglion cell layer to inner plexiform layer thickness, outer retina layer thickness, subfoveal choroidal thickness, and choroidal vascularity index were measured using optical coherence tomography. Foveal avascular zone area, vascular density, and flow void area were measured using optic
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23

Tissot van Patot, M. C., J. Bendrick-Peart, V. E. Beckey, N. Serkova, and L. Zwerdlinger. "Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia." American Journal of Physiology-Lung Cellular and Molecular Physiology 287, no. 3 (2004): L525—L532. http://dx.doi.org/10.1152/ajplung.00203.2003.

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Vascularity is increased in placentas from high- compared with low-altitude pregnancies. An angiogenic response to hypoxia may protect an organ from further hypoxic insult by increasing blood flow and oxygen delivery to the tissue. We hypothesized that increased placental vascularity is sufficient to adapt to high altitude. Therefore, indexes of hypoxic stress would not be present in placentas from successful high-altitude pregnancies. Full-thickness placental biopsies were 1) collected and frozen in liquid nitrogen within 5 min of placental delivery and 2) fixed in formalin for stereologic an
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Nathan, Saminathan S., Andrew G. Huvos, Jorge E. Casas-Ganem, et al. "Tumour Interstitial Fluid Pressure May Regulate Angiogenic Factors in Osteosarcoma." Annals of the Academy of Medicine, Singapore 38, no. 12 (2009): 1041–47. http://dx.doi.org/10.47102/annals-acadmedsg.v38n12p1041.

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Purpose: We have previously shown that osteosarcomas have states of increased interstitial fluid pressure (IFP) which correlate with increased proliferation and chemosensitivity. In this study, we hypothesized that constitutively raised IFP in osteosarcomas regulates angiogenesis. Materials and Methods: Sixteen patients with the clinical diagnosis of osteosarcomas underwent blood flow and IFP readings by the wick-in-needle method at the time and location of open biopsy. Vascularity was determined by capillary density in the biopsy specimens. We performed digital image analysis of immunohistoch
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Karaca, Dilhan, Aynur Dıraçoğlu, and Feyza Önder. "Can optical coherence tomography angiography be a first line ophthalmological evaluation in patients with Behçet’s disease?" Archives of Rheumatology 38, no. 2 (2022): 200–208. http://dx.doi.org/10.46497/archrheumatol.2023.9494.

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Objectives: This study aimed to investigate whether early ocular findings can be demonstrated with optical coherence tomography angiography in patients with Behçet's disease. Patients and methods: Thirty-seven eyes of 22 patients with Behçet’s disease with ocular involvement, 48 eyes of 26 Behçet patients without any ocular involvement, and 44 eyes of 22 healthy controls were included, for a total of 70 patients (39 males, 31 females; mean age: 42.3±11.7 years; range, 18 to 65 years), in the cross-sectional study conducted between September 2019 and April 2020. The parameters analyzed were the
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Kim, Eun Kyung, Mi Jang, Yoon Jung Choi, and Nam Hoon Cho. "Renal Cell Carcinoma With Hemangioma-Like Features: Diagnostic Implications and Review of the Literature." International Journal of Surgical Pathology 27, no. 6 (2019): 631–38. http://dx.doi.org/10.1177/1066896919840435.

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Renal cell carcinoma (RCC) with clear cell morphology may show a prominent delicate vascularity. In this article, we report the morphologic and immunohistochemical features of a clear cell papillary RCC mimicking hemangioblastoma and a clear cell RCC mimicking hemangioma. Case 1 showed tubular and papillary growth of clear cells with distinctive areas of capillary proliferation and admixed stromal-like cells resembling a hemangioblastoma. Case 2 consisted of homogeneously delicate microvascular proliferations resembling a capillary hemangioma with scattered inconspicuous clear cells. The clear
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Asghar, Adil, Ravi Kant Narayan, Ashutosh Kumar, and Shagufta Naaz. "The transcortical vessel is replacement of cortical capillary or a separate identity in diaphyseal vascularity." Anatomy & Cell Biology 53, no. 1 (2020): 107. http://dx.doi.org/10.5115/acb.19.171.

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Suciu, Corina-Iuliana, Vlad-Ioan Suciu, and Simona-Delia Nicoara. "Optical Coherence Tomography (Angiography) Biomarkers in the Assessment and Monitoring of Diabetic Macular Edema." Journal of Diabetes Research 2020 (December 31, 2020): 1–10. http://dx.doi.org/10.1155/2020/6655021.

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Retinopathy is one of the most severe diabetes-related complications, and macular edema is the major cause of central vision loss in patients with diabetes mellitus. Significant progress has been made in recent years in optical coherence tomography and angiography technology. At the same time, various parameters have been attributed the role of biomarkers creating the frame for new monitoring and treatment strategies and offering new insights into the pathogenesis of diabetic retinopathy and diabetic macular edema. In this review, we gathered the results of studies that investigated various sp
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Uyar, Seyit, Ayşe Balkarlı, Muhammet Kazım Erol, et al. "Assessment of the Relationship between Diabetic Retinopathy and Nailfold Capillaries in Type 2 Diabetics with a Noninvasive Method: Nailfold Videocapillaroscopy." Journal of Diabetes Research 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/7592402.

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Background and Objectives. Nailfold capillaroscopy is an easy and noninvasive technique used to investigate dermal microvasculature. Traditional investigations of vascularity do not detect changes until they are well-established in type 2 diabetics. The objective of the current study was to evaluate nailfold capillaries in type 2 diabetes mellitus patients and to determine the association of retinopathy with changes in the nailfold capillaries.Materials and Methods. Capillaroscopic findings by nailfold capillaroscopy and fundoscopic examinations were assessed in 216 patients with type 2 diabet
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Viswambharan, Vivek, M. Lakshmi Narayana, N. Reddy Chaithanya, B. N. Kumarguru, and Bijjam Sushma. "A rare case of mesenchymal hamartoma of cheek masquerading as hemangioma." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 1 (2019): 200. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20195714.

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<p class="abstract">Hamartomas are non-neoplastic, tumor-like masses characterized by irregular overgrowth in tissues of its origin, resulting from inborn errors that occur during embryonic development and are present from birth. They may develop from any of the three germinal layers of which mesodermal-derived overgrowth is the most common. Hamartomas may be seen anywhere in the body and most often arises from lung, liver, spleen, kidney, gastrointestinal tract, and rarely in the head and neck region. A 23-year-old lady presented with a painless left cheek swelling for three months. On
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JONES, NIA W., NICK RAINE-FENNING, and GEORGE BUGG. "3D POWER DOPPLER IN OBSTETRICS." Fetal and Maternal Medicine Review 22, no. 1 (2011): 1–24. http://dx.doi.org/10.1017/s0965539510000136.

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Flow is defined as the amount of fluid, ordinarily blood, passing per unit time (usually per minute). Perfusion is defined as the volume of blood flowing through a mass of tissue per unit time. The standard measure of perfusion is millilitres of fluid per second per 100 g of tissue (or 100 ml in volume) i.e. the fractional blood volume in an area divided by the mean transit time through the area, where the area is scaled to a 100 ml of tissue. The fractional vascular volume is an index of the physiological vascularity of a region and represents the proportion of tissue occupied by blood. Sever
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Vonnahme, Kimberly A., and Caleb O. Lemley. "Programming the offspring through altered uteroplacental hemodynamics: how maternal environment impacts uterine and umbilical blood flow in cattle, sheep and pigs." Reproduction, Fertility and Development 24, no. 1 (2012): 97. http://dx.doi.org/10.1071/rd11910.

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As placental growth and vascularity precedes exponential fetal growth, not only is proper establishment of the placenta important, but also a continual plasticity of placental function throughout gestation. Inadequate maternal environment, such as nutritional plane, has been documented to alter fetal organogenesis and growth, thus leading to improper postnatal growth and performance in many livestock species. The timing and duration of maternal nutritional restriction appears to influence the capillary vascularity, angiogenic profile and vascular function of the placenta in cattle and sheep. I
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Adair, T. H., W. J. Gay, and J. P. Montani. "Growth regulation of the vascular system: evidence for a metabolic hypothesis." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 259, no. 3 (1990): R393—R404. http://dx.doi.org/10.1152/ajpregu.1990.259.3.r393.

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Prolonged imbalances between the perfusion capabilities of the blood vessels and the metabolic requirements of the tissue cells often lead to modification of the vasculature to satisfy the tissue needs. This homeostatic response appears to be bidirectional, since the vascularity of a tissue can increase or decrease in parallel with primary changes in metabolic rate. The factors that mediate the responses are not well understood, but oxygen has been implicated as a major control element, since vessel growth increases during hypoxic conditions and decreases during hyperoxic conditions. The follo
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Mędrzycka, Justyna, Grzegorz Rotuski, Radosław Różycki, and Joanna Gołębiewska. "Retinal Vascularity in Military Pilots in Relation to the Type of Aircraft, Flight Altitude and Total Hours of Flight." Journal of Clinical Medicine 14, no. 8 (2025): 2671. https://doi.org/10.3390/jcm14082671.

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Background: The aim of the study was to assess retinal circulation in military pilots, as well as to determine the relationship between the type of aircraft, flight altitude, total hours of flight time and parameters of retinal circulation, using OCT angiography (OCT-A). Methods: This cross-sectional study enrolled 44 military pilots and 44 controls. The inclusion criteria encompassed healthy adult men. Due to the fact that military pilots cannot suffer from any vision defects or any other eye disease, the exclusion criteria concerned the control group and included refractive error exceeding −
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Chanpakdee, Channipa. "Exercise training improves age-related changes in cerebral capillary vascularity through the upregulation of PI3K / Akt signaling." Chulalongkorn Medical Journal 63, no. 4 (2019): 229–38. http://dx.doi.org/10.58837/chula.cmj.63.4.3.

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Ilse, B. R., M. R. O'Neil, G. P. Lardy, L. P. Reynolds та K. A. Vonnahme. "Impacts of linseed meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes". Canadian Journal of Animal Science 92, № 3 (2012): 297–306. http://dx.doi.org/10.4141/cjas2011-104.

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Ilse, B. R., O'Neil, M. R., Lardy, G. P., Reynolds, L. P. and Vonnahme, K. A. 2012. Impacts of linseed meal and estradiol-17β on cellularity, angiogenic and vasoactive factor mRNA expression, and vascularity of the uterus in ovariectomized ewes. Can. J. Anim. Sci. 92: 297–306. The objective of the current study was to determine the estrogenic potential of the phytoestrogen secoisolariciresinol diglycoside (SDG) found in linseed meal (LSM) on uterine cell proliferation, vascularity, and angiogenic factor mRNA expression. Ovariectomized ewes (n=48) were fed a diet containing 12.5% LSM for 0, 1,
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Harik, Nada, Sami I. Harik, Ning-Tsu Kuo, Katsuyuki Sakai, Ronald J. Przybylski, and Joseph C. LaManna. "Time-course and reversibility of the hypoxia-induced alterations in cerebral vascularity and cerebral capillary glucose transporter density." Brain Research 737, no. 1-2 (1996): 335–38. http://dx.doi.org/10.1016/0006-8993(96)00965-1.

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Guduru, Abhilash, Arushi Gupta, Mudit Tyagi, Subhadra Jalali, and Jay Chhablani. "Optical coherence tomography angiography characterisation of Best disease and associated choroidal neovascularisation." British Journal of Ophthalmology 102, no. 4 (2017): 444–47. http://dx.doi.org/10.1136/bjophthalmol-2017-310586.

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AimsTo characterise the vasculature of the retina in patients with Best vitelliform dystrophy, including those with choroidal neovascularisation (CNV), using optical coherence tomography angiography (OCTA) and correlate with fluorescein angiography (FA).MethodsThis prospective observational study included 19 eyes of 10 patients with Best disease. Using OCTA, all layers of retina were qualitatively characterised for each eye. Patients with CNV also underwent FA, and areas of CNV were measured by OCTA and FA and correlated.ResultsRetinal characteristics revealed 14 (74%) eyes with abnormal fovea
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Adler, Ronald Steven. "Musculoskeletal ultrasound: a technical and historical perspective." Journal Of Ultrasonography 23, no. 95 (2023): 170–85. http://dx.doi.org/10.15557/jou.2023.0027.

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During the past four decades, musculoskeletal ultrasound has become popular as an imaging modality due to its low cost, accessibility, and lack of ionizing radiation. The development of ultrasound technology was possible in large part due to concomitant advances in both solid-state electronics and signal processing. The invention of the transistor and digital computer in the late 1940s was integral in its development. Moore’s prediction that the number of microprocessors on a chip would grow exponentially, resulting in progressive miniaturization in chip design and therefore increased computat
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D’Aloisio, Rossella, Maria Ludovica Ruggeri, Giada D’Onofrio, et al. "Choroidal and Retinal Vascular Findings in Patients with COVID-19 Complicated with Pneumonia: Widefield Imaging." Diagnostics 13, no. 6 (2023): 1114. http://dx.doi.org/10.3390/diagnostics13061114.

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Purpose: The purpose of this study was to analyze choroidal and retinal vascular alterations of both the macula and midperiphery areas in patients hospitalized for COVID-19 infection complicated with pneumonia within 30 days from discharge. Methods: A total of 46 eyes of 23 subjects with a history of symptomatic COVID-19 infection and recent hospitalization for pneumonia were enrolled in this observational study. Patients had not been previously vaccinated against COVID-19. A group of patients homogenous for age and sex was enrolled as controls. Microvascular retinal and choroidal features of
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Daneshi, Mojtaba, Jessica Syring, Yssi Entzie, et al. "PSXIV-22 Impact of Maternal Plane of Nutrition in Combination with Strategic One-Carbon Metabolites Supplementation During Early Pregnancy on Vascularity and Cell Proliferation in the Fetal Small Intestine." Journal of Animal Science 101, Supplement_3 (2023): 540–41. http://dx.doi.org/10.1093/jas/skad281.636.

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Abstract Objective of our study were to investigate the impact of maternal nutrition during early pregnancy on the vascularity and proliferation of fetal intestine and whether supplementing one-carbon metabolites (OCM) could mitigate any changes arising from altered maternal nutrition. We used a 2 x 2 factorial arrangement of treatments with two levels of heifer gain: control (CON; 0.45 kg/d) and restricted (RES; -0.23 kg/d), with and without (+/- OCM) supplementation. Crossbred Angus beef heifers were estrous synchronized and bred via artificial insemination with single-sire female-sexed seme
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Allen, Ariana, Cason B. Robbins, Suzanna Joseph, et al. "Angioarchitectural alterations in the retina and choroid in frontotemporal dementia." PLOS ONE 19, no. 11 (2024): e0312118. http://dx.doi.org/10.1371/journal.pone.0312118.

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Objective Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder that affects the frontal and temporal lobes of the brain, leading to cognitive decline and personality changes. The objective of this cross-sectional study was to characterize angioarchitectural changes in the retina and choroid of individuals with FTD compared to cognitively normal controls using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods Cross-sectional comparison of patients with FTD and controls with normal cognition. All participants underwent Mini-Mental State Examination (MMSE
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Joseph, Suzanna, Cason B. Robbins, Alice Haystead, et al. "Characterizing differences in retinal and choroidal microvasculature and structure in individuals with Huntington’s Disease compared to healthy controls: A cross-sectional prospective study." PLOS ONE 19, no. 1 (2024): e0296742. http://dx.doi.org/10.1371/journal.pone.0296742.

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Objective To characterize retinal and choroidal microvascular and structural changes in patients who are gene positive for mutant huntingtin protein (mHtt) with symptoms of Huntington’s Disease (HD). Methods This study is a cross-sectional comparison of patients who are gene positive for mHtt and exhibit symptoms of HD, either motor manifest or prodromal (HD group), and cognitively normal individuals without a family history of HD (control group). HD patients were diagnosed by Duke movement disorder neurologists based on the Unified Huntington’s Disease Rating Scale (UHDRS). Fovea and optic ne
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Contreras-Correa, Zully E., Riley D. Messman, Hector Sanchez-Rodriguez, Derris D. Burnett, and Caleb O. Lemley. "395 Young Scholar Award Talk: Melatonin: A Promising Therapeutic for Compromised Pregnancies." Journal of Animal Science 100, Supplement_3 (2022): 201–2. http://dx.doi.org/10.1093/jas/skac247.366.

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Abstract Poorly functioning placenta restricts oxygen and nutrient supply to the fetus resulting in fetal nutrient deficiency and intrauterine growth restriction. Intrauterine growth restriction dramatically increases neonatal mortality and those who survive are more prone to experience metabolic diseases such as cardiovascular diseases, hypertension, and type 2 diabetes in later life. Therefore, the placenta plays a critical role in the developmental origins of health and diseases. Currently, there is a vast effort evaluating the effects of compromised pregnancies such as maternal undernutrit
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Jung, Suk Hoon, Sang Un Yi, Bo-Een Hwang, Young Gun Park, and Young-Hoon Park. "Optical coherence tomography analysis at initial diagnosis in patients with retinitis pigmentosa and associated cystoid macular edema." PLOS One 20, no. 6 (2025): e0325654. https://doi.org/10.1371/journal.pone.0325654.

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This retrospective study analyzed optical coherence tomography (OCT) findings in 130 eyes of 130 patients with retinitis pigmentosa (RP) at initial diagnosis, including 42 with cystoid macular edema (CME) and 88 without, between September 2016 and March 2024. The CME group exhibited increased central macular thickness (CMT) (257.50 ± 104.98 µm vs. 171.40 ± 73.15 µm, p = 0.000), whereas the non-CME group had greater subfoveal choroidal thickness (SCT) (294.52 ± 122.85 µm vs. 246.98 ± 87.31 µm, p = 0.043), total choroidal area (TCA) (4.64 ± 1.98 mm² vs. 3.82 ± 1.34 mm², p = 0.031), stromal area
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Kaplan, Hilton M., and Gerald E. Loeb. "Preventing Ischial Pressure Ulcers: I. Review of Neuromuscular Electrical Stimulation." Applied Bionics and Biomechanics 8, no. 3-4 (2011): 323–31. http://dx.doi.org/10.1155/2011/934910.

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Objective:Pressure ulcers (PUs) are common and debilitating wounds that arise when immobilized patients cannot shift their weight. Treatment is expensive and recurrence rates are high. Pathophysiological mechanisms include reduced bulk and perfusion of chronically atrophic muscles as well as prolonged occlusion of blood flow to soft tissues from lack of voluntary postural shifting of body weight. This has suggested that PUs might be prevented by reanimating the paralyzed muscles using neuromuscular electrical stimulation (NMES). A review of the published literature over the past 2 decades is d
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Sukpat, Supakanda, Nipan Isarasena, Jutamas Wongphoom, and Suthiluk Patumraj. "Vasculoprotective Effects of Combined Endothelial Progenitor Cells and Mesenchymal Stem Cells in Diabetic Wound Care: Their Potential Role in Decreasing Wound-Oxidative Stress." BioMed Research International 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/459196.

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To investigate whether the combined endothelial progenitor cells (EPCs) and mesenchymal stem cells (MSCs) could enhance angiogenesis and wound healing in diabetic mice. Balb/c nude mice were divided into five groups, including a control group, diabetic group (DM), DM injected with 1 × 106 cells MSCs, DM injected with 1 × 106 cells EPCs, and DM injected with combined 0.5 × 106 cells MSCs and 0.5 × 106 cells EPCs. After seven weeks, the mice were anesthetized, and bilateral full-thickness excision skin wounds were made on the dorsorostral back. The percentage of wound closure in DM group decreas
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Oglat, Ammar A. "A review of ultrasound contrast media." F1000Research 12 (November 7, 2023): 1444. http://dx.doi.org/10.12688/f1000research.140131.1.

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There have been numerous attempts over the past 50 years to develop efficient ultrasound contrast media (UCM) for both cardiac and noncardiac uses. In other words, the first UCM was created in the 1980s as a result of early reports from the 1960s documenting the findings of ultrasound contrast enhancement by microscopic gaseous bubbles during echocardiographic tests. A nontoxic UCM (Definity, Optison, Sonazoid, and SonoVue are some of the current commercial contrast media for echography that have shown promise in a range of on- and off-label clinical purposes) that may be injected intravenousl
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Viboolvorakul, Sheepsumon, and Suthiluk Patumraj. "Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS." BioMed Research International 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/230791.

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This study aimed to investigate the effect of exercise training on age-induced microvascular alterations in the brain. Additionally, the association with the protein levels of vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS) was also assessed. Male Wistar rats were divided into four groups: sedentary-young (SE-Young,n=5), sedentary aged (SE-Aged,n=8), immersed-aged (IM-Aged,n=5), and exercise trained-aged (ET-Aged, 60 minutes/day and 5 days/week for 8 weeks,n=8) rats. The MAPs of all aged groups, SE-Aged, IM-Aged, and ET-Aged, were significantly higher tha
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Radek, Katherine A., Elizabeth J. Kovacs, Richard L. Gallo, and Luisa A. DiPietro. "Acute ethanol exposure disrupts VEGF receptor cell signaling in endothelial cells." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 1 (2008): H174—H184. http://dx.doi.org/10.1152/ajpheart.00699.2007.

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Physiological angiogenesis is regulated by various factors, including signaling through vascular endothelial growth factor (VEGF) receptors. We previously reported that a single dose of ethanol (1.4 g/kg), yielding a blood alcohol concentration of 100 mg/dl, significantly impairs angiogenesis in murine wounds, despite adequate levels of VEGF, suggesting direct effects of ethanol on endothelial cell signaling (40). To examine the mechanism by which ethanol influences angiogenesis in wounds, we employed two different in vitro angiogenesis assays to determine whether acute ethanol exposure (100 m
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