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Artykuły w czasopismach na temat „Cartilage”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Claassen, Horst, Martin Schicht, Bernd Fleiner, et al. "Different Patterns of Cartilage Mineralization Analyzed by Comparison of Human, Porcine, and Bovine Laryngeal Cartilages." Journal of Histochemistry & Cytochemistry 65, no. 6 (2017): 367–79. http://dx.doi.org/10.1369/0022155417703025.

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Laryngeal cartilages undergo a slow ossification process during aging, making them an excellent model for studying cartilage mineralization and ossification processes. Pig laryngeal cartilages are similar to their human counterparts in shape and size, also undergo mineralization, facilitating the study of cartilage mineralization. We investigated the processes of cartilage mineralization and ossification and compared these with the known processes in growth plates. Thyroid cartilages from glutaraldehyde-perfused male minipigs and from domestic pigs were used for X-ray, light microscopic, and t

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Gong, Huchen, Yutao Men, Xiuping Yang, Xiaoming Li, and Chunqiu Zhang. "Experimental Study on Creep Characteristics of Microdefect Articular Cartilages in the Damaged Early Stage." Journal of Healthcare Engineering 2019 (November 13, 2019): 1–9. http://dx.doi.org/10.1155/2019/8526436.

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Traumatic joint injury is known to cause cartilage deterioration and osteoarthritis. In order to study the mechanical mechanism of damage evolution on articular cartilage, taking the fresh porcine articular cartilage as the experimental samples, the creep experiments of the intact cartilages and the cartilages with different depth defect were carried out by using the noncontact digital image correlation technology. And then, the creep constitutive equations of cartilages were established. The results showed that the creep curves of different layers changed exponentially and were not coincident

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Bender-Heine, Adam, Michelle Russell, Allen Rickards, et al. "Optimal Costal Cartilage Graft Selection According to Cartilage Shape: Anatomical Considerations for Rhinoplasty." Facial Plastic Surgery 33, no. 06 (2017): 670–74. http://dx.doi.org/10.1055/s-0037-1607972.

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AbstractCostal cartilage grafting is a commonly used reconstruction procedure, particularly in rhinoplasty. Although costal cartilage is broadly used in reconstructive surgery, there are differing opinions regarding which costal cartilage levels provide the most ideal grafts. Grafts are typically designed to match the shape of the recipient site. The shapes of costal cartilage grafts have been described as “boat-shaped,” “C-shaped,” “canoe-shaped,” “U-shaped,” “crescent-shaped,” “L-shaped,” “semilunar,” “straight,” and “Y-shaped.” The shapes of costal cartilages are thought to lend themselves

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Wardale, R. J., and V. C. Duance. "Quantification and immunolocalisation of porcine articular and growth plate cartilage collagens." Journal of Cell Science 105, no. 4 (1993): 975–84. http://dx.doi.org/10.1242/jcs.105.4.975.

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The collagens of growth plate and articular cartilage from 5–6 month old commercial pigs were characterised. Growth plate cartilage was found to contain less total collagen than articular cartilage as a proportion of the dry weight. Collagen types I, II, VI, IX and XI are present in both growth plate and articular cartilage whereas type X is found exclusively in growth plate cartilage. Types III and V collagen could not be detected in either cartilage. Type I collagen makes up at least 10% of the collagenous component of both cartilages. There are significant differences in the ratios of the q

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Korvick, Donna, and Kyriacos Athanasiou. "Variations in the mechanical properties of cartilage from the canine scapulohumeral joint." American Journal of Veterinary Research 58, no. 9 (1997): 949–53. http://dx.doi.org/10.2460/ajvr.1997.58.09.949.

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Abstract Objective To measure the intrinsic material properties of scapulohumeral joint cartilage in adult dogs and determine whether regional differences exist within or between the humeral and glenoid cartilages. Samples Paired shoulder joints from 7 clinically normal adult dogs. Procedure An automated indentation apparatus was used to obtain the intrinsic mechanical properties of the cartilage at 7 sites on each joint surface. Results Topographic variations in mechanical properties of the glenoid and humeral cartilages were observed. The largest aggregate modulus (HA) for the humerus was se

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Wardale, R. J., and V. C. Duance. "Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis." Journal of Cell Science 107, no. 1 (1994): 47–59. http://dx.doi.org/10.1242/jcs.107.1.47.

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The articular and growth plate cartilages of osteochondrotic pigs were examined and compared with those from clinically normal animals. Both types of osteochondrotic cartilage showed considerable localised thickening apparently due to a lack of ossification. Histological examination of cartilage lesions demonstrated a breakdown in the normal pattern of chondrocyte maturation. Articular cartilage lesions lacked mature clones of chondrocytes in the calcifying region. Growth plate cartilage showed an accumulation of disorganised hypertrophic chondrocytes rather than the well-defined columns seen

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Holmbeck, Kenn, Paolo Bianco, Kali Chrysovergis, Susan Yamada, and Henning Birkedal-Hansen. "MT1-MMP–dependent, apoptotic remodeling of unmineralized cartilage." Journal of Cell Biology 163, no. 3 (2003): 661–71. http://dx.doi.org/10.1083/jcb.200307061.

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Skeletal tissues develop either by intramembranous ossification, where bone is formed within a soft connective tissue, or by endochondral ossification. The latter proceeds via cartilage anlagen, which through hypertrophy, mineralization, and partial resorption ultimately provides scaffolding for bone formation. Here, we describe a novel and essential mechanism governing remodeling of unmineralized cartilage anlagen into membranous bone, as well as tendons and ligaments. Membrane-type 1 matrix metalloproteinase (MT1-MMP)–dependent dissolution of unmineralized cartilages, coupled with apoptosis

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Li, Xue, Jin Duo Ye, Chun Qui Zhang, Qian Qian Tian, Xian Kang Wang, and Li Min Dong. "Numerical Simulation about Stretching Process in Different Layers of Cartilage." Applied Mechanics and Materials 441 (December 2013): 480–83. http://dx.doi.org/10.4028/www.scientific.net/amm.441.480.

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Cartilage with complex structure is a porous viscoelastic material. The direction of arrangement of collagen fibers in different layer regions directly affects the mechanical properties of the cartilage layer region. It is very important to use the method of numerical simulation for studying cartilage damage and repair through experimental measurements of cartilage mechanical parameters of the different layers. Because of the relatively small size of the cartilage, it is very difficult to measure mechanical parameters of cartilages by tensile test. The paper for main problems in the tensile te

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Wulkan, Marcelo, Alvaro Julio de Andrade Sá, and Nivaldo Alonso. "Modified technique to increase nostril cross-sectional area after using rib and septal cartilage graft over alar nasal cartilages." Acta Cirurgica Brasileira 27, no. 10 (2012): 713–19. http://dx.doi.org/10.1590/s0102-86502012001000008.

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PURPOSE: Describe a modified technique to increase nostril cross-sectional area using rib and septal cartilage graft over alar nasal cartilages. METHODS: A modified surgical technique was used to obtain, carve and insert cartilage grafts over alar nasal cartilages. This study used standardized pictures and measured 90 cadaveric nostril cross-sectional area using Autocad®; 30 were taken before any procedure and 60 were taken after grafts over lateral crura (30 using costal cartilage and 30 using septal cartilage). Statistical analysis were assessed using a model for repeated measures and ANOVA

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Souza, Thiago Sasso Carmona de, João Victor Buttini, Mariana Sasso Carmona de Souza, Pedro Aguiar Soares, Maria Fernanda Pioli Torres, and Caio Marcio Correia Soares. "MORSELIZED CARTILAGE GRAFT: AN ANALYSIS OF THE AREA AND PERIMETER MEASUREMENTS OF THIS VERSATILE OPTION FOR MODERN RHINOPLASTY." Journal of Contemporary Diseases and Advanced Medicine 1, no. 2 (2022): 10–24. http://dx.doi.org/10.14436/jcdam.1.2.010-024.oar.

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Introduction: One of the biggest issues in the field of rhinoplasty is the use of grafts, one of which is the morselized cartilage graft. Few studies to date have sought to demonstrate the changes in size suffered by cartilage after the morselization process. Objective: To compare changes in area and perimeter of septal and auricular cartilages after being submitted to two degrees of morselization. Material and Methods: This was a cross-sectional, comparative, and analytical study. Septum and ear cartilages were separated into two groups: Septal Cartilage Group (SCG) and Auricular Cartilage Gr

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Åberg, Thomas, Ritva Rice, David Rice, Irma Thesleff, and Janna Waltimo-Sirén. "Chondrogenic Potential of Mouse Calvarial Mesenchyme." Journal of Histochemistry & Cytochemistry 53, no. 5 (2005): 653–63. http://dx.doi.org/10.1369/jhc.4a6518.2005.

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Facial and calvarial bones form intramembranously without a cartilagenous model; however, cultured chick calvarial mesenchyme cells may differentiate into both osteoblasts and chondroblasts and, in rodents, small cartilages occasionally form at the sutures in vivo. Therefore, we wanted to investigate what factors regulate normal differentiation of calvarial mesenchymal cells directly into osteoblasts. In embryonic mouse heads and in cultured tissue explants, we analyzed the expression of selected transcription factors and extracellular matrix molecules associated with bone and cartilage develo

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12

Schroeder, Walter A., Margaret H. Cooper, and William H. Friedman. "The Histologic Effect of Hypervitaminosis A on Laryngeal Cartilages." Otolaryngology–Head and Neck Surgery 96, no. 6 (1987): 533–37. http://dx.doi.org/10.1177/019459988709600602.

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This study investigated the role of hypervitaminosis A on the developing larynx. Pregnant rats received a dose of 100,000 units of Vitamin A on either Day 8 or Day 11 of gestation. The hyaline laryngeal cartilages of the neonatal rats were studied. The cricoid and arytenoid cartilages appeared to be the most affected. There was a pronounced central disorganization of the structure of the cartilage, with numerous swollen lacunae devoid of chondrocytes. The thyroid cartilage was the least affected. The center of the cartilage displayed a minimal amount of disorganization, when compared to the co

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13

Shu, Cindy, Carl Flannery, Christopher Little, and James Melrose. "Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs." International Journal of Molecular Sciences 20, no. 3 (2019): 579. http://dx.doi.org/10.3390/ijms20030579.

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Background: Cartilage regeneration requires a balance of anabolic and catabolic processes. Aim: To examine the susceptibility of fibromodulin (FMOD) and lumican (LUM) to degradation by MMP-13, ADAMTS-4 and ADAMTS-5, the three major degradative proteinases in articular cartilage, in cartilage development and in osteoarthritis (OA). Methods: Immunolocalization of FMOD and LUM in fetal foot and adult knee cartilages using an FMOD matrix metalloprotease (MMP)-13 neoepitope antibody (TsYG11) and C-terminal anti-FMOD (PR184) and anti-LUM (PR353) antibodies. The in vitro digestion of knee cartilage w

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Khan, M. M., and S. R. Parab. "Average thickness of tragal cartilage for slicing techniques in tympanoplasty." Journal of Laryngology & Otology 129, no. 5 (2015): 435–39. http://dx.doi.org/10.1017/s0022215115000055.

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AbstractBackground:Cartilage-perichondrial grafts are often used for tympanic membrane and middle-ear reconstructions. Tragal and conchal cartilages are most frequently used for this purpose. Studies have shown that slicing the cartilage to less than 0.5 mm thickness improves acoustic benefit. However, the thickness of the cartilage in a given population may not be uniform.Objective:This descriptive cross-sectional study aimed to determine the average thickness of tragal cartilage (in terms of age and sex) in an Indian population.Method:A prospective study of 61 tragal cartilages harvested dur

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Hayes, Anthony J., John Whitelock, and James Melrose. "Regulation of FGF-2, FGF-18 and Transcription Factor Activity by Perlecan in the Maturational Development of Transitional Rudiment and Growth Plate Cartilages and in the Maintenance of Permanent Cartilage Homeostasis." International Journal of Molecular Sciences 23, no. 4 (2022): 1934. http://dx.doi.org/10.3390/ijms23041934.

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The aim of this study was to highlight the roles of perlecan in the regulation of the development of the rudiment developmental cartilages and growth plate cartilages, and also to show how perlecan maintains permanent articular cartilage homeostasis. Cartilage rudiments are transient developmental templates containing chondroprogenitor cells that undergo proliferation, matrix deposition, and hypertrophic differentiation. Growth plate cartilage also undergoes similar changes leading to endochondral bone formation, whereas permanent cartilage is maintained as an articular structure and does not

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Divakaran, Sindu, Bethanney Janney J, Priyanga R, Sindoora Jalagam, Ramya R C, and Shakthi R. "Electro arthrography: Recording Electrical Potentials At the Elbow Joint." International Journal of Engineering & Technology 7, no. 2.25 (2018): 25. http://dx.doi.org/10.14419/ijet.v7i2.25.12361.

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Electroarthrography (EAG) is a recent technology proposed to detect cartilage degradation. It is used to record electrical potentials generated on the surface of elbow while the joint undergoes compressive loading. The aim of this work is to understand the generation of EAG signals and to differentiate between the healthy and unhealthy elbow based on its cartilage degradation. It has been found that EAG signals originate from the cartilages based on the simulated and measured potential values distributions. Unhealthy cartilages produce varying current density with specific potential distributi

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Zhang, Hong, Xiaopeng Zhao, Zhiguang Zhang, Weiwei Chen, and Xinli Zhang. "An Immunohistochemistry Study of Sox9, Runx2, and Osterix Expression in the Mandibular Cartilages of Newborn Mouse." BioMed Research International 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/265380.

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The purpose of this study is to investigate the spacial expression pattern and functional significance of three key transcription factors related to bone and cartilage formation, namely, Sox9, Runx2, and Osterix in cartilages during the late development of mouse mandible. Immunohistochemical examinations of Sox9, Runx2, and Osterix were conducted in the mandibular cartilages of the 15 neonatal C57BL/6N mice. In secondary cartilages, both Sox9 and Runx2 were weakly expressed in the polymorphic cell zone, strongly expressed in the flattened cell zone and throughout the entire hypertrophic cell z

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Trivisonno, Angelo, Steven R. Cohen, Guy Magalon, et al. "Fluid Cartilage as New Autologous Biomaterial in the Treatment of Minor Nose Defects: Clinical and Microscopic Difference Amongst Diced, Crushed, and Fluid Cartilage." Materials 12, no. 7 (2019): 1062. http://dx.doi.org/10.3390/ma12071062.

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Developing cartilage constructs with injectability, appropriate matrix composition, and persistent cartilaginous phenotype remains an enduring challenge in cartilage repair. Fourteen patients with minor contour deformity were treated with fluid cartilage filler gently injected as autologous fluid graft in deep planes of defect of the nose that were close to the bone or the cartilage. A computerized tomographic scan control was performed after 12 months. Pearson’s Chi-square test was used to investigate differences in cartilage density between native and newly formed cartilages. The endpoints w

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Lychagin, A. V., S. V. Ivannikov, V. I. Yusupov, et al. "Laser treatment of chondromalacia lesions in the articular cartilage." Laser Medicine 25, no. 4 (2022): 9–15. http://dx.doi.org/10.37895/2071-8004-2021-25-4-9-15.

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Objective: to select optimal parameters of two-wave near-infrared laser irradiation for the arthroscopic treatment of chondromalacia foci in the articular cartilage. Material and methods. Bull articular cartilages were treated with laser light delivered by a fifi ber and having various parameters. Human articular cartilages with chondromalacia foci taken during the total knee replacement were also treated with laser light delivered by a fifi ber and having various parameters. The processed cartilage samples were examined macroscopically and then histologically. Changes in the structure of ar[1

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Hayashi, Kei, Brian Caserto, Mary Norman, Hollis Potter, Matthew Koff, and Sarah Pownder. "Magnetic Resonance Imaging T2 Values of Stifle Articular Cartilage in Normal Beagles." Veterinary and Comparative Orthopaedics and Traumatology 31, no. 02 (2018): 108–13. http://dx.doi.org/10.3415/vcot-17-03-0093.

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Objectives The purpose of this study was to evaluate regional differences of canine stifle articular cartilage using the quantitative magnetic resonance imaging (MRI) technique of T2 mapping. Methods Fourteen stifle joints from seven juvenile male Beagle dogs with no evidence or prior history of pelvic limb lameness were imaged ex vivo using standard of care fast spin echo MRI and quantitative T2 mapping protocols. Regions of interest were compared between the femoral, patellar and tibial cartilages, as well as between the lateral and medial femorotibial compartments. Limbs were processed for

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Yi, Hee-Gyeong, Yeong-Jin Choi, Jin Woo Jung, et al. "Three-dimensional printing of a patient-specific engineered nasal cartilage for augmentative rhinoplasty." Journal of Tissue Engineering 10 (January 2019): 204173141882479. http://dx.doi.org/10.1177/2041731418824797.

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Autologous cartilages or synthetic nasal implants have been utilized in augmentative rhinoplasty to reconstruct the nasal shape for therapeutic and cosmetic purposes. Autologous cartilage is considered to be an ideal graft, but has drawbacks, such as limited cartilage source, requirements of additional surgery for obtaining autologous cartilage, and donor site morbidity. In contrast, synthetic nasal implants are abundantly available but have low biocompatibility than the autologous cartilages. Moreover, the currently used nasal cartilage grafts involve additional reshaping processes, by meticu

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QIU, LULU, XUEMEI MA, LILAN GAO, YUTAO MEN, and CHUNQIU ZHANG. "ANALYSIS OF THE MECHANICAL STATE OF THE HUMAN KNEE JOINT WITH DEFECT CARTILAGE IN STANDING." Journal of Mechanics in Medicine and Biology 16, no. 08 (2016): 1640021. http://dx.doi.org/10.1142/s0219519416400212.

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Knee joint is the hub of human lower limb movement and it is also an important weight-bearing joint, which has the characteristics of load-bearing and heavy physical activities. So the knee joint becomes the predilection site of clinical disease. Once people have the cartilage lesions, their daily life will be affected seriously. The simulation of the knee joint lesions could provide help for clinical knee-joint treatment. Based on the complete model of knee joint, this paper use the finite element method to analyze the biomechanical characteristics of the defective knee joint. The results of

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Fertuzinhos, Aureliano, Marta A. Teixeira, Miguel Goncalves Ferreira, et al. "Thermo-Mechanical Behaviour of Human Nasal Cartilage." Polymers 12, no. 1 (2020): 177. http://dx.doi.org/10.3390/polym12010177.

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The aim of this study was to undergo a comprehensive analysis of the thermo-mechanical properties of nasal cartilages for the future design of a composite polymeric material to be used in human nose reconstruction surgery. A thermal and dynamic mechanical analysis (DMA) in tension and compression modes within the ranges 1 to 20 Hz and 30 °C to 250 °C was performed on human nasal cartilage. Differential scanning calorimetry (DSC), as well as characterization of the nasal septum (NS), upper lateral cartilages (ULC), and lower lateral cartilages (LLC) reveals the different nature of the binding w

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Bagher, Zohreh, Negin Asgari, Parisa Bozorgmehr, Seyed Kamran Kamrava, Rafieh Alizadeh, and Alexander Seifalian. "Will Tissue-Engineering Strategies Bring New Hope for the Reconstruction of Nasal Septal Cartilage?" Current Stem Cell Research & Therapy 15, no. 2 (2020): 144–54. http://dx.doi.org/10.2174/1574888x14666191212160757.

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The nasal septal cartilage plays an important role in the growth of midface and as a vertical strut preventing the collapse of the nasal bones. The repair of nasal cartilage defects remains a major challenge in reconstructive surgery. The tissue engineering strategy in the development of tissue has opened a new perspective to generate functional tissue for transplantation. Given the poor regenerative properties of cartilage and a limited amount of autologous cartilage availability, intense interest has evoked for tissue engineering approaches for cartilage development to provide better outcome

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Li, Yefu, and Lin Xu. "Advances in understanding cartilage remodeling." F1000Research 4 (August 28, 2015): 642. http://dx.doi.org/10.12688/f1000research.6514.1.

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Cartilage remodeling is currently among the most popular topics in osteoarthritis research. Remodeling includes removal of the existing cartilage and replacement by neo-cartilage. As a loss of balance between removal and replacement of articular cartilage develops (particularly, the rate of removal surpasses the rate of replacement), joints will begin to degrade. In the last few years, significant progress in molecular understanding of the cartilage remodeling process has been made. In this brief review, we focus on the discussion of some current “controversial” observations in articular carti

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Bista, Neha, Pradesh Ghimire, and Mahgn Rances Collao. "Correlation of Amount of Cigarette Smoking with Thickness and Elasticity of Distal Femoral Cartilages using Sono-Elastography Techniques of Ultrasound, a Cross-Sectional Study." Nepalese Journal of Radiology 11, no. 2 (2021): 2–10. http://dx.doi.org/10.3126/njr.v11i2.38205.

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Introduction: Cigarette smoking is a well-known etiology for chronic musculoskeletal system disorders, like osteoarthritis, affecting the distal femoral cartilages. However, recent studies show protective effects of smoking against osteoarthritis. Ultrasound is an easily accessible and reliable imaging tool for the evaluation of the cartilages, measurement of their thickness, and tissue stiffness. This study seeks to objectively show the effects of smoking by affecting their knee joints’ cartilage and clarify whether it has a chondroprotective effect, or support the usual evidence that smoking

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Liu, Hui, Tingting Zhang, Min Liu, Chunhong Wang, and Jinfeng Yan. "Acupuncture Delays Cartilage Degeneration through Upregulating SIRT1 Expression in Rats with Osteoarthritis." Evidence-Based Complementary and Alternative Medicine 2021 (December 31, 2021): 1–11. http://dx.doi.org/10.1155/2021/2470182.

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Silent mating type information regulation 2 homolog 1 (SIRT1) has been reported to inhibit osteoarthritic gene expression in chondrocytes. Here, efforts in this study were made to unveil the specific role of SIRT1 in the therapy of acupuncture on cartilage degeneration in osteoarthritis (OA). Specifically, OA was established by the anterior cruciate ligament transection method in the right knee joint of rats, subsequent to which acupuncture was performed on two acupoints. Injection with shSIRT1 sequence–inserted lentiviruses was conducted to investigate the role of SIRT1 in acupuncture-mediate

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Muhammad Sohaib Nadeem, Ujala Ali, Adnan Zeb, and Muhammad Yousaf Khan. "Chondrosarcoma of Thyroid Cartilage - Case Report." Pakistan Armed Forces Medical Journal 74, no. 4 (2024): 1222–24. http://dx.doi.org/10.51253/pafmj.v74i4.7351.

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Chondrosarcomas of the larynx are rare, mainly arising from cartilages of the larynx, including cricoid cartilage, thyroid cartilage epiglottis, and arytenoid cartilages. These can be misdiagnosed initially as benign malignancy. Historically, the treatment used to be surgery, which usually is total thyroidectomy with a loss of voice forever. No gross improvements in treatment occurred, and surgery was the mainstay of the treatment. Chondrosarcoma from other anatomical regions can very rarely cause thyroid metastasis. Here, we present a case of an elderly male who presented with a multinodular

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Wansin, Yew, Mohd Juzaila Abd Latif Yew, Sharifah Majedah Idrus Alhabshi, Amaluddin Mahmud, and Mohammed Rafiq Abdul Kadri. "Correlation of Biomechanical Properties and Grayscale of Articular Cartilage using Low-Field Magnetic Resonance Imaging." International Journal of Engineering & Technology 7, no. 4.26 (2018): 1–5. http://dx.doi.org/10.14419/ijet.v7i4.26.22128.

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Osteoarthritis is a joint disease that caused by the progression of degenerative articular cartilage tissue. The degeneration of the articular cartilage resulted in alteration of the biomechanical properties. Magnetic resonance imaging (MRI) has become the most potential imaging technique to assess the condition of the articular cartilage. However, most of the previous studies of articular cartilage were performed using high-field MRI units. Therefore, this study aimed to examine the correlation between the biomechanical properties of articular cartilage and the image grayscale using low-field

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Rashid, Balsam Muqdad, Sadiq Jaafar Hamandi, and Eman Ghadban Khalil. "Measurement of Cartilage Deformation in Intact Knee Joints under Compressive Loading." Al-Nahrain Journal for Engineering Sciences 25, no. 1 (2022): 44–48. http://dx.doi.org/10.29194/njes.25010044.

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Many joints in the body depend on cartilage for their mechanical function. Since cartilage lacks the ability to self-heal when injured, treatments and replacements for damaged cartilage have been created in recent decades. The mechanical tests had an important role in the treatment and designing of the replaced cartilage. There are two types of cartilages in the knees: fibrocartilage (the meniscus, it is a special type of cartilage) and hyaline cartilage. Its mechanical properties are important because structural failure of cartilage is closely related with joint disorders. This study aimed to

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Ravikalyan, Dodda, Thukani Sathanantham Shanmugarajan, and Uppuluri Varuna Naga Venkata Arjun. "Polymeric hydrogel-assisted chondro regenerative approaches towards cartilage injury therapy an emerging treatment option." Journal of Medical Pharmaceutical and Allied Sciences 12, no. 4 (2023): 5999–6006. http://dx.doi.org/10.55522/jmpas.v12i4.4789.

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An injury to the cartilage is a physical disruption of the cartilage's architecture, resulting in fluid loss and pain to the individual. The earliest possible diagnosis of various cartilage defect complications is vital to facilitate healing. Moreover, to fasten the healing process of the cartilage defect, tissue-engineered materials should have several key characteristics, including ideal porosity, and minimal cytotoxicity. The primary characteristic of polymeric hydrogel scaffolds is that they offer a moist environment that accelerates the cartilage repair and good biocompatibility. Most oft

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Orsini, Paul G., Charles W. Raker, Charles F. Reid, and Peter Mann. "Xeroradiographs evaluation of the equine larynx." American Journal of Veterinary Research 50, no. 6 (1989): 845–49. https://doi.org/10.2460/ajvr.1989.50.06.845.

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SUMMARY The normal radiographic anatomy of the equine larynx was determined by use of xeroradiography and dissection. The body and laminae of the thyroid cartilage, the muscular process of the arytenoid cartilages, and the dorsal lamina and arch of the cricoid cartilage had radiographic evidence of mineralization (calcification) and/or ossification in clinically normal horses. There was a significant (P < 0.01) increase in the degree of mineralization of the thyroid and arytenoid cartilages with advancing age. Horses with diagnosis of arytenoid chondrosis (arytenoid chondral dysplasia, aryt

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Wang, Haidong, Xiaodong Yao, and Chengjun Wu. "The Therapeutic Effect of Herbal Mixture in Repairing Degenerated Joint." Journal of Biomaterials and Tissue Engineering 13, no. 2 (2023): 282–86. http://dx.doi.org/10.1166/jbt.2023.3238.

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Osteoarthritis (OA) is a degenerative joint disease due to the limited capacity to repair itself. There is an increasing need for novel and more effective alternatives to promote cartilage joint regeneration. Natural compounds as herbal remedies are ideal to be considered to treat OA. In order to explore the functional herbal remedy, we investigated the efficacy of herbal mixture along with bone mesenchymal stem cells (BMSCs) in repairing rat cartilage tissues. Forty SD rats were randomly divided into four groups. A cartilage injury models by a drilling was made. The histological H&E analy

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Ciliberti, Federica Kiyomi, Lorena Guerrini, Arnar Evgeni Gunnarsson, et al. "CT- and MRI-Based 3D Reconstruction of Knee Joint to Assess Cartilage and Bone." Diagnostics 12, no. 2 (2022): 279. http://dx.doi.org/10.3390/diagnostics12020279.

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For the observation of human joint cartilage, X-ray, computed tomography (CT) or magnetic resonance imaging (MRI) are the main diagnostic tools to evaluate pathologies or traumas. The current work introduces a set of novel measurements and 3D features based on MRI and CT data of the knee joint, used to reconstruct bone and cartilages and to assess cartilage condition from a new perspective. Forty-seven subjects presenting a degenerative disease, a traumatic injury or no symptoms or trauma were recruited in this study and scanned using CT and MRI. Using medical imaging software, the bone and ca

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Hong, Seok Jin, Minseok Lee, Connie J. Oh, and Sehwan Kim. "Monitoring of Biological Changes in Electromechanical Reshaping of Cartilage Using Imaging Modalities." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/7089017.

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Electromechanical reshaping (EMR) is a promising surgical technique used to reshape cartilage by direct current and mechanical deformation. It causes local stress relaxation and permanent alterations in the shape of cartilage. The major advantages of EMR are its minimally invasive nature and nonthermal electrochemical mechanism of action. The purpose of this study is to validate that EMR does not cause thermal damage and to observe structural changes in post-EMR cartilage using several imaging modalities. Three imaging modality metrics were used to validate the performance of EMR by identifyin

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CHEN, JING, CHUNGEN GUO, HONGSHENG LI, XIAOQIN ZHU, SHUYUAN XIONG, and JIANXIN CHEN. "NONLINEAR SPECTRAL IMAGING OF ELASTIC CARTILAGE IN RABBIT EARS." Journal of Innovative Optical Health Sciences 06, no. 03 (2013): 1350024. http://dx.doi.org/10.1142/s1793545813500247.

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Elastic cartilage in the rabbit external ear is an important animal model with attractive potential value for researching the physiological and pathological states of cartilages especially during wound healing. In this work, nonlinear optical microscopy based on two-photon excited fluorescence and second harmonic generation were employed for imaging and quantifying the intact elastic cartilage. The morphology and distribution of main components in elastic cartilage including cartilage cells, collagen and elastic fibers were clearly observed from the high-resolution two-dimensional nonlinear op

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Lukeneder, Petra, and Alexander Lukeneder. "Mineralized belemnoid cephalic cartilage from the late Triassic Polzberg Konservat-Lagerstätte (Austria)." PLOS ONE 17, no. 4 (2022): e0264595. http://dx.doi.org/10.1371/journal.pone.0264595.

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Although hyaline cartilage is widely distributed in various invertebrate groups such as sabellid polychaetes, molluscs (cephalopods, gastropods) and a chelicerate arthropod group (horseshoe crabs), the enigmatic relationship and distribution of cartilage in taxonomic groups remains to be explained. It can be interpreted as a convergent trait in animal evolution and thus does not seem to be a vertebrate invention. Due to the poor fossil record of cartilaginous structures, occurrences of mineralized fossil cartilages are important for evolutionary biology and paleontology. Although the biochemic

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Burch, W. M., and J. J. Van Wyk. "Triiodothyronine stimulates cartilage growth and maturation by different mechanisms." American Journal of Physiology-Endocrinology and Metabolism 252, no. 2 (1987): E176—E182. http://dx.doi.org/10.1152/ajpendo.1987.252.2.e176.

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The mechanisms by which triiodothyronine (T3) stimulates growth and maturation of growth-plate cartilage in vitro were studied by incubating embryonic chick pelvic cartilages in serum-free medium in the presence and absence of T3 for 3 days. To determine whether T3 might stimulate production of somatomedins by the cartilage, medium from cartilage incubated with and without T3 was assayed for somatomedin C (Sm-C) by radioimmunoassay. No difference in Sm-C content was found. However, cartilage incubated with T3 and increasing amounts of human Sm-C (0.5-20 ng/ml) weighed more and had greater amou

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Fujii, Yuta, Lin Liu, Lisa Yagasaki, Maiko Inotsume, Tomoki Chiba, and Hiroshi Asahara. "Cartilage Homeostasis and Osteoarthritis." International Journal of Molecular Sciences 23, no. 11 (2022): 6316. http://dx.doi.org/10.3390/ijms23116316.

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Healthy limb joints are important for maintaining health and attaining longevity. Endochondral ossification (the replacement of cartilage with bone, occurring during skeletal development) is essential for bone formation, especially in long-axis bones. In contrast to endochondral ossification, chondrocyte populations in articular cartilage persist and maintain joint tissue into adulthood. Articular cartilage, a connective tissue consisting of chondrocytes and their surrounding extracellular matrices, plays an essential role in the mechanical cushioning of joints in postnatal locomotion. Osteoar

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Wu, Jiang, Bin Zhao, Wei Luo, et al. "Arthroscopy combined with high tibial osteotomy promotes cartilage regeneration in osteoarthritis." Journal of Orthopaedic Surgery 31, no. 1 (2023): 102255362311653. http://dx.doi.org/10.1177/10225536231165357.

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Background To investigate the effect of arthroscopy combined with high tibial osteotomy (HTO) on cartilage regeneration in patients with knee osteoarthritis. Methods A retrospective analysis of 50 patients with varus and medial compartment osteoarthritis of the knee treated by arthroscopy combined with HTO. One year after the operation, a second-look arthroscopy was performed to observe the cartilage regeneration. The regeneration of cartilage was evaluated by different pathological staining of some of the new cartilage. Finally, part of the new cartilages ( n = 6) were taken for quantitative

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Jurvelin, J., A.-M. Säämänen, J. Arokoski, H. J. Helminen, I. Kiviranta, and M. Tammi. "Biomechanical Properties of the Canine Knee Articular Cartilage as Related to Matrix Proteoglycans and Collagen." Engineering in Medicine 17, no. 4 (1988): 157–62. http://dx.doi.org/10.1243/emed_jour_1988_017_042_02.

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The instant, creep and equilibrium responses of canine knee articular cartilages were determined after a constant load application with an in situ indentation creep test and related to the chemical composition of the tissue. Instantly, the cartilage stiffness correlated inversely with the proportion of proteoglycans (PGs) extractable with guanidium chloride. The tibial cartilage, rich in PGs but relatively poor in collagen, showed a low resistance to instant rearrangement of the solid matrix after load application. However, the resistance of the tibial cartilage to water flow during creep defo

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Aeschlimann, D., A. Wetterwald, H. Fleisch, and M. Paulsson. "Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes." Journal of Cell Biology 120, no. 6 (1993): 1461–70. http://dx.doi.org/10.1083/jcb.120.6.1461.

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Calcifying cartilages show a restricted expression of tissue transglutaminase. Immunostaining of newborn rat paw bones reveals expression only in the epiphyseal growth plate. Tissue transglutaminase appears first intracellularly in the proliferation/maturation zone and remains until calcification of the tissue in the lower hypertrophic zone. Externalization occurs before mineralization. Subsequently, the enzyme is present in the interterritorial matrix during provisional calcification and in the calcified cartilage cores of bone trabeculae. In trachea, mineralization occurring with maturation

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Poole, A. R., C. Webber, I. Pidoux, H. Choi, and L. C. Rosenberg. "Localization of a dermatan sulfate proteoglycan (DS-PGII) in cartilage and the presence of an immunologically related species in other tissues." Journal of Histochemistry & Cytochemistry 34, no. 5 (1986): 619–25. http://dx.doi.org/10.1177/34.5.3701029.

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A monoclonal antibody to a core-protein-related epitope of a small dermatan sulfate-rich proteoglycan (DS-PGII) isolated from adult bovine articular cartilage (22) was used to localize this molecule, or molecules containing this epitope, in bovine articular cartilages, in cartilage growth plate, and in other connective tissues. Using an indirect method employing peroxidase-labeled pig anti-mouse immunoglobulin G, DS-PGII was shown to be present mainly in the superficial zone of adult articular condylar cartilage of the metacarpal-phalangeal joint. In fetal articular and epiphyseal cartilages,

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Yamamoto, Etsuo, Michitaka Iwanaga, and Manabu Fukumoto. "Histologic Study of Homograft Cartilages Implanted in the Middle Ear." Otolaryngology–Head and Neck Surgery 98, no. 6 (1988): 546–51. http://dx.doi.org/10.1177/019459988809800602.

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We examined conditions of the micro-sliced homograft cartilages implanted in the middle ear, implanted cartilages removed at revision surgery or implanted cartilages removed at the second stage of staged tympanoplasty, both macroscopically and histologically. Macroscopically, the appearance and shape of the cartilages remained unchanged, with no evidence of erosion. There was no evidence of any foreign body reaction or rejection phenomenon. In general, no marked histologic changes of the matrix tissues were found, although chondrocytes showed degenerative changes. There was partial absorption

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Chetina, E. V., and E. V. Chetina. "Inhibition of activity of collagen degradation in cartilage of patients with osteoarthrosis byactivation of glycolysis." Osteoporosis and Bone Diseases 14, no. 1 (2011): 8–12. http://dx.doi.org/10.14341/osteo201118-12.

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Aim. To study the effect of glycolysis activators deferrioxamine (DFO), CoCl2, V(SO4)2 and mimosine on collagen cleavage activity by collagenase in osteoarthritic (OA) articular cartilage explants. Materials and methods. 32 OA articular cartilages obtained after arthroplasty were examined in the study. Cartilages were cultured in the presence of 10-50μM DFO, CoCl2, V(SO4)2 or mimosine. Collagen cleavage activity was measured by ELISA. Inhibition of protein or DNA synthesis in the presence of [3H]-labeled proline or thymidine, respectively, was used for evaluation of examined agent toxicity. Re

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Tarniţă, Daniela, Marius Catana, and Dan Nicolae Tarnita. "Modeling and Finite Element Analysis of the Human Knee Joint Affected by Osteoarthritis." Key Engineering Materials 601 (March 2014): 147–50. http://dx.doi.org/10.4028/www.scientific.net/kem.601.147.

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The paper presents a complex three-dimensional model of the human knee joint, containing bones, ligaments, menisci, tibial and femoral cartilages. To investigate the role of the articular cartilage in the developing of the osteoarthritis, to analyze and simulate the biomechanical behavior of the human knee joint, a finite element analysis was performed. The non-linearities are due to the presence of the contact elements modeled between components surfaces and to the nonlinear properties of the cartilage, applying a load of 800 N and 1500 N, for 0o in flexion. The results show that misalignment

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McBurney, Kim M., and Glenda M. Wright. "Chondrogenesis of a non-collagen-based cartilage in the sea lamprey, Petromyzon marinus." Canadian Journal of Zoology 74, no. 12 (1996): 2118–30. http://dx.doi.org/10.1139/z96-241.

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Chondrogenesis of the trabeculae, non-collagen-based cartilages in prolarval stages of the sea lamprey, Petromyzon marinus, was examined by light and electron microscopy. Chondrogenesis of the trabecular cartilages in prolarval lampreys commenced with the formation of mesenchymal condensations. Two peaks in mesenchymal cell density occurred, one prior to condensation formation and a second immediately before cartilage differentiation. The possibility of inductive influences by epithelio-mesenchymal interactions on the initiation of chondrogenesis is discussed. Bilateral condensations first app

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Haider, Muhammad Adnan, Ali Shah Hussain, Muhammad Touqeer, and Aaima Siddiqui. "Enhancing Physiological Significance in Cartilage-on-Chip Models: A Review of 3D Microenvironment Strategies for Chondrocyte Confinement." Scientia. Technology, Science and Society 2, no. 6 (2025): 62–74. https://doi.org/10.59324/stss.2025.2(6).07.

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Traditional two-dimensional (2D) cartilage culture systems present significant limitations in replicating the complex architecture, mechanical cues, and biochemical environment of native cartilage tissue. These flat, static models often fail to maintain chondrocyte phenotype and matrix production, reducing their utility in disease modeling and drug screening. In response, cartilage-on-chip systems and 3D microenvironments have emerged as promising alternatives, offering more physiologically relevant platforms that better simulate the in vivo cartilage niche. Recent technological advances inclu

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Kirasirova, E. A., N. V. Lafutkina, R. A. Rezakov, R. F. Mamedov, and I. F. Al-Assaf. "PATHOMORPHOLOGICAL CHANGES IN THE CARTILAGE OF THE TRACHEA DEPENDING ON TERMS OF THE INTUBATION." Folia Otorhinolaryngologiae et Pathologiae Respiratoriae 25, no. 3 (2019): 87–93. http://dx.doi.org/10.33848/foliorl23103825-2019-25-3-87-93.

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Objective - to study the nature and prevalence of pathological changes in the cartilage of the trachea depending on the duration of intubation according to the results of pathomorphological studies. Materials and methods. Pathomorphological study of cartilage of the anterior tracheal wall was carried out on 37 patients at different times of mechanical ventilation. Depending on the timing of the ventilator before the tracheostomy, all patients were divided into three groups. In 10 people, the duration of ventilation until tracheostomy was no more than 3 days, in 15 people - 4 -7 days and in 12

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Schaffer, Rose, Yun-Seok Kang, Angelo Marcallini, Bengt Pipkorn, John H. Bolte, and Amanda M. Agnew. "Comparison of Bending Properties in Paired Human Ribs with and without Costal Cartilage." Stapp Car Crash Journal 68, no. 1 (2024): 104–54. https://doi.org/10.4271/2024-22-0006.

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<div class="section abstract"><div class="htmlview paragraph">Thoracic injuries, most frequently rib fractures, commonly occur in motor vehicle crashes. With an increased reliance on human body models (HBMs) for injury prediction in various crash scenarios, all thoracic tissues and structures require more comprehensive evaluation for improvement of HBMs. The objective of this study was to quantify the contribution of costal cartilage to whole rib bending properties in physical experiments. Fifteen bilateral pairs of 5th human ribs were included in this study. One rib within each pa

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