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Rozprawy doktorskie na temat „Catarrhalis”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 1 lutego 2022

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1

Enright, Mark Charles. "Molecular characterization of Moraxella catarrhalis." Thesis, University of Aberdeen, 1994. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=158242.

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<I>Moraxella catarrhalis</I> is a gram-negative diplococcus which until recently was thought to be a harmless commensal. Increasing awareness has established the pathogenic nature of this organism and it is now recognised as a major cause of otitis media in children, exacerbations of chronic bronchitis in elderly patients and an occasional cause of invasive disease. <I>M. catarrhalis</I> is spread nosocomially especially in respiratory wards containing elderly patients. This study evaluated four methods for typing nosocomially spread isolates:- immunoblotting with normal human serum (NHS), and
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2

Gill, Lyndell R. "Moraxella (Branhamella) Catarrhalis: A Molecular Epidemiology Study." Digital Commons @ East Tennessee State University, 1995. https://dc.etsu.edu/etd/2684.

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Moraxella (Branhamella) catarrhalis is the third-most-frequently isolated microorganism associated with acute exacerbations of chronic bronchitis in patients during their stay at the Mountain Home VA Medical Center (MHVAMC). In order to develop a practical, epidemiologically-meaningful typing method for M. (B.) catarrhalis, we tested two methods based on analysis of chromosomal DNA for typeability, reproducibility, and ability to differentiate between unrelated strains (discriminatory power, D). M. (B.) catarrhalis isolants from MHVAMC from 7/1/87-6/30/88 were grown overnight i
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3

Bullard, Brian. "Characterization of the Moraxella catarrhalis Hag Adhesin." University of Toledo Health Science Campus / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=mco1195596894.

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Stawska, Agnieszka A. "Purification of Aspartate Transcarbamoylase from Moraxella (Branhamella) catarrhalis." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc2864/.

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The enzyme, aspartate transcarbamoylase (ATCase) from Moraxella (Branhamella) catarrhalis, has been purified. The holoenzyme has a molecular mass of approximately 510kDa, harbors predominantly positive charges and is hydrophobic in nature. The holoenzyme possesses two subunits, a smaller one of 40 kDa and a larger one of 45 kDa. A third polypeptide has been found to contribute to the overall enzymatic activity, having an approximate mass of 55 kDa. The ATCase purification included the generation of cell-free extract, streptomycin sulfate cut, 60 °C heat step, ammonium sulfate cut, dialysis an
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5

Attia, Ahmed Sherif. "The USPA2 protein and serum resistance of Moraxella Catarrhalis." Access to abstract only; dissertation is embargoed until after 5/15/2007, 2006. http://www4.utsouthwestern.edu/library/ETD/etdDetails.cfm?etdID=145.

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Fowler, Michael A. (Michael Allen) 1961. "Characterization of Aspartate Transcarbamoylase and Dihydroorotase in Moraxella Catarrhalis." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc277709/.

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Bacterial aspartate transcarbamoylases (ATCase's) are divided into three classes that correspond to taxonomic relationships within the bacteria. The opportunistic pathogen Moraxeila catarrhalis has undergone several reclassifications based on traditional microbiological criteria. The previously uncharacterized ATCase from M. catarrhalis was purified to homogeneity and its chemical properties characterized. The ATCase from M. catarrhalis is a class C ATCase with an apparent molecular mass of 480-520 kDa. The M. catarrhalis ATCase is a dodecomer composed of six 35 kDa polypeptides and six 45 kDa
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7

Bowman, Melissa Lynne. "Biochemical characterization of Moraxella catarrhalis strains associated with Otitis media." Thesis, Georgia Institute of Technology, 2001. http://hdl.handle.net/1853/25397.

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8

Easton, Donna Meredith, and n/a. "Functional and Antigenic Characterisation of the Moraxella catarrhalis protein M35." University of Canberra. n/a, 2008. http://erl.canberra.edu.au./public/adt-AUC20081217.083105.

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This thesis reports the characterisation of a novel outer membrane protein (OMP) from M. catarrhalis, designated M35, with a molecular mass of 36.1 kDa. This protein is structurally homologous to classic Gram-negative porins, such as OMP C from E. coli and OMP K36 from K. pneumoniae, with a predicted structure of 8 surface loops connecting 16 antiparallel -sheets. Comparison of the DNA sequences of the M35 genes from 18 diverse clinical isolates showed that the gene was highly conserved (99.6-100 % of nucleotides) with only one isolate (ID78LN266) having base variations that resulted in amino
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9

Jonatat, Carola [Verfasser]. "Die Aktivierung des humanen Bronchialepithels durch Moraxella catarrhalis / Carola Jonatat." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023464616/34.

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10

Yeo, Siew-Fah. "Epidemiology and antimicrobial resistance of Haemophilus influenzae and Moraxella catarrhalis." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309743.

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11

Nguyen, Kim Thuy. "Construction of a Physical Map of Moraxella (Branhamella) catarrhalis Strain ATCC25238." Thesis, University of North Texas, 1999. https://digital.library.unt.edu/ark:/67531/metadc279104/.

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In order to gain a better understanding of this microorganismand its role in human pathogenesis, a physical map of Moraxella catarrhalis type strain ATCC25238 was constructed using pulsed field gel electrophoresis (PFGE) in combination with Southern hybridization techniques. Restriction endonucleases Not I, Rsr II, and Sma I were used to digest the chromosomal DNA. An overlapping circular map was generated by cross-hybridization of isolated radiolabeled fragments of Moraxella catarrhalis genomic DNA to dried PFGE gels. The number and location of the 16S and 23S ribosomal RNA genes were determi
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12

Vigelahn, Manuel [Verfasser]. "Molekulare Mechanismen der Moraxella catarrhalis induzierten Apoptose pulmonaler Epithelzellen / Manuel Vigelahn." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1079524452/34.

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13

Campbell, Sara J. "Mechanisms of Moraxella catarrhalis Induced Immune Signaling in the Pulmonary Epithelium." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1268141520.

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14

Akimana, Christine. "Structural and Functional Analysis of Moraxella catarrhalis Adhesins MCAP and OMPCD." University of Toledo Health Science Campus / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=mco1180025995.

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15

Slevogt, Hortense Gisela [Verfasser]. "Molekulare Mechanismen der Interaktion von Moraxella catarrhalis mit pulmonalen Epithelzellen / Hortense Gisela Slevogt." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023783436/34.

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16

Chen, Miao. "Moraxella catarrhalis-induced innate immune responses in human pulmonary epithelial cells and monocytes." Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1260375737.

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Dissertation (Ph.D.)--University of Toledo, 2009.<br>["In partial fulfillment of the requirements for the degree of Doctor of Philosophy in Biomedical Sciences."] Title from title page of PDF document. Bibliography: p. 80-112.
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17

Heinrich, Annina. "Die Bedeutung von CEACAM3 für die Moraxella catarrhalis induzierte Aktivierung von humanen Granulozyten." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/18831.

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Die COPD (chronic obstructive pulmonary disease) ist eine weltweit vorkommende, chronisch obstruktive Erkrankung der Lunge. Sie gilt als vierthäufigste Todesursache weltweit, wobei ein Viertel der akuten bakteriellen Exazerbationen auf eine Infektion mit Moraxella catharralis zurückzuführen sind. Sowohl das akute, als auch das chronische Entzündungsbild der COPD wird überwiegend durch neutrophile Granulozyten in den Atemwegen bestimmt, die neben antimikrobiellen Effektorfunktionen durch Freisetzung von Zytokinen auch die Entzündungsreaktion bzw. Immunantwort regulieren können. In dieser Arbeit
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18

Serrano, Aybar Pablo. "Mechanisms of induction of CCL20/MIP3-α in lung epithelial cells by Moraxella catarrhalis". University of Toledo Health Science Campus / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=mco1222875028.

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19

Cumbes, Bevan Christopher. "Responses of the Opportunistic Pathogen Moraxella (Branhamella) catarrhalis to Clinically Relevant Changes in Environmental Conditions." Thesis, University of the West of England, Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.524691.

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The Gram-negative bacterium, Moraxella ca tarrhalis, is an opportunistic human pathogen that colonises the nasopharynx of healthy individuals. The disease most often associated with this organism is otitis media in children, though it is increasingly implicated in lower respiratory tract infections and even some cases of meningitis, endocarditis and bacteraemia. The most commonly quoted sites of colonisation and infection are the nasopharynx, tympanic cavity and lower respiratory tract. The different microenvironments found at these infection sites suggest a range of conditions in which the ba
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20

Zabel, Solveig. "Die Bedeutung von CEACAM1 für die Moraxella-catarrhalis-induzierte TLR2-vermittelte Aktivierung des respiratorischen Epithels /." Berlin : Mbv, Mensch- & -Buch-Verl, 2009. http://d-nb.info/998778087/04.

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21

JAGER, BEAUVEIL AURELIE. "Activite in vitro comparee de differents antibiotiques vis-a-vis de streptococcus pneumoniae, haemophilus influenzae et moraxella catarrhalis : enquete epidemiologique au c.h.r. de metz au cours de l'annee 1990." Nancy 1, 1993. http://www.theses.fr/1993NAN1A202.

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Zabel, Solveig [Verfasser]. "Die Bedeutung von CEACAM1 für die Moraxella catarrhalis-induzierte TLR2-vermittelte Aktivierung des respiratorischen Epithels / Solveig Zabel." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1024004317/34.

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23

Carbonneau, Julie. "Caractérisation de la réponse immune naturellement acquise chez l'homme au cours de la colonisation avec Moraxella (Branhamella) catarrhalis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0004/MQ43791.pdf.

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24

Zahradnik, Sabrina [Verfasser]. "Die M. catarrhalis – induzierte Verminderung viraler Rezeptoren und deren Bedeutung für die antivirale Immunantwort in pulmonalem Epithel / Sabrina Zahradnik." Berlin : Freie Universität Berlin, 2014. http://d-nb.info/1048047431/34.

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Westman, Eva. "Experimental acute otitis media : aspects on treatment, protection and structural changes." Doctoral thesis, Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-162.

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26

Taylor, LaShan Denise. "Antibiotic Resistance: Multi-Drug Profiles and Genetic Determinants." [Johnson City, Tenn. : East Tennessee State University], 2001. http://etd-submit.etsu.edu/etd/theses/available/etd-1210101-134219/unrestricted/taylorl121101a.pdf.

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27

Steiner, Tamara Alice [Verfasser]. "Die Bedeutung des humanen β-Defensin-3 für die Infektion von humanem respiratorischem Epithel mit Moraxella catarrhalis / Tamara Alice Steiner". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1052221475/34.

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28

Beeck, Andreas. "Molekularepidemiologische Charakterisierung der BRO-[beta]-Laktamasen [BRO-beta-Laktamasen] europäischer Moraxella catarrhalis Isolate und Analyse der In-vitro-Aktivität verschiedener Antibiotika." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971101582.

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29

Balder, Rachel. "Type V Secretion System Exoproteins and their Roles in the Adherence of the Gram-Negative Bacterial Pathogens Moraxella catarrhalis, Burkholderia pseudomallei and Burkholderia mallei." University of Toledo Health Science Campus / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=mco1188909479.

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30

Uskudar, Guclu Aylin. "Identification Of Streptococcus Pneumoniae, Haemophilus Influenzae, And Moraxella Catarrhalis From Sputum Samples Of Patients With Community Acquired Pneumonia By Polymerase Chain Reaction." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12605920/index.pdf.

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iv The present work describes the evaluation of the value of polymerase chain reaction in diagnosis of pneumonia caused by the most common three bacterial pathogens<br>Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis from sputum of patients with community acquired pneumonia admitted to The Department of Pulmonary Diseases of Gulhane Military Medical Academy. In this study, 107 sputa from 142 patients with suspected community acquired pneumonia were used to survey the causative agents. Identification of the pathogens was performed by sputum Gram stain and conventional
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31

Heinrich, Annina [Verfasser], Arturo [Gutachter] Zychlinsky, Hortense [Gutachter] Slevogt, and Ralf [Gutachter] Schumann. "Die Bedeutung von CEACAM3 für die Moraxella catarrhalis induzierte Aktivierung von humanen Granulozyten / Annina Heinrich ; Gutachter: Arturo Zychlinsky, Hortense Slevogt, Ralf Schumann." Berlin : Humboldt-Universität zu Berlin, 2018. http://d-nb.info/1185495614/34.

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32

Bergström, Jennie. "Nested PCR for distinguishing Haemophilus haemolyticus from Haemophilus influenzae and Cloning and expression of fragmented Moraxella catarrhalis IgD-binding protein in E. coli." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8014.

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<p>ABSTRACT</p><p>Nontypable Haemophilus influenzae is a common cause of otitis, sinusitis and conjunctivitis. It is the most common bacterial pathogen associated with chronic obstructive pulmonary disease (COPD). Studies have shown that nonpathogenic Haemophilus haemolyticus are often mistaken for Haemophilus influenzae due to an absent hemolytic reaction on blood agar. Distinguishing H. haemolyticus from H. influenzae is important to prevent unnecessary antibiotic use, and to understand the role of H. influenzae in clinical infections. In this study, PCR-primers for amplifying 16S rDNA seque
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Tiwari, Krishna Nand [Verfasser]. "Vergleich unterschiedlicher Methoden zur Quantifizierung der Adhäsion von Moraxella catarrhalis an pulmonalen Epithelzellen und Etablierung eines neuen Fluoreszenz-basierten Adhäsionsassays / Krishna Nand Tiwari." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2010. http://d-nb.info/1027814549/34.

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Alnahas, Safa [Verfasser], and Ulrich [Akademischer Betreuer] Steinhoff. "IL-17 and TNF-alpha are essential mediators of M. catarrhalis triggered exacerbation of HDM allergic airway inflammation / Safa Alnahas ; Betreuer: Ulrich Steinhoff." Marburg : Philipps-Universität Marburg, 2017. http://d-nb.info/1137323345/34.

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Qaiem, Maqami Lily [Verfasser]. "Die Bedeutung der Protein-Kinase C und ihrer Isoformen für die Moraxella catarrhalis induzierte IL-8-Sekretion in humanem pulmonalen Epithel / Lily Qaiem Maqami." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1025239954/34.

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Erman, Evelina. "Analys av antikroppar mot Moraxella catarrhalis hos patienter med multipelt myelom, Waldenströms makroglobulinemi och monoklonal gammopati av oklar signifikans med ”enzyme-linked immunosorbent assay”." Thesis, Linnéuniversitetet, Institutionen för naturvetenskap, NV, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-8301.

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Försämrat immunförsvar och ökad risk att drabbas av bakterie- och virusinfektioner förekommer hos patienter med blodsjukdomarna multipelt myelom, Waldenströms makroglobulinemi samt hos vissa patienter med blodsjukdomen monoklonal gammopati av oklar signifikans. Infektionerna kräver ofta antibiotikabehandling och behandling med antivirala medel. I dagsläget är det svårt att förutsäga vilka av patienterna som kommer att drabbas av svåra och ibland livshotande infektioner. Därför ges många av patienterna förebyggande antibiotikabehandling. I studiens början sattes en enzyme-linked immunosorbent a
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Al-Saadi, M. H. "Pathogenesis of malignant catarrhal fever in cattle." Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3025852/.

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Sharp, Colin Peter. "The molecular basis of malignant catarrhal fever." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/29991.

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Alcelaphine herpesvirus-1 (A1HV-1) is gammaherpesvirus that can cause the devastating, fatal disease malignant catarrhal fever (MCF) in susceptible ruminant hosts but not in its natural host the blue wildebeest. The purpose of this study is to characterise four unique open reading frames (ORFs) of A1HV-1 and examine their contribution to viral pathogenesis. These ORFs are located at the left hand end of the genome, a region known to contain unique transforming and immunomodulatory genes in other gammaherpesviruses, and are predicted to encode two small gene products with no significant homolog
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Swa, Sandi. "Large granular lymphocyte dysregulation in malignant catarrhal fever." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/30020.

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The role of virus-infected large granular lymphocytes in pathogenesis of MCF is not clear. In the absence of defined viral antigens the main objective of this study was to investigate how MCF viruses interfere with LGL proliferation and cytotoxicity. In this study, IL-2 independence and a cell surface phenotype of T/NK cells was demonstrated in most cell lines analysed. The period of survival and growth without exogenous IL-2 was variable but always exceeded that of uninfected control cells. The possible role of IL-15 (a pro-inflammatory cytokine with actions similar to IL-2) in LGL function w
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Esnault, Olivier Bertagnoli Stéphane. "Étude sur l'analyse de risque de la Fièvre Catarrhale Ovine (Bluetongue) dans le bassin ovin laitier de Roquefort cas particulier des centres d'insémination artificielle /." [S.l.] : [s.n.], 2008. http://oatao.univ-toulouse.fr/2086/1/debouch_2086.pdf.

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Hemati, Behzad. "Interactions entre le virus Bluetongue et cellules dendritiques lymphatiques du mouton." Versailles-St Quentin en Yvelines, 2008. http://www.theses.fr/2008VERS0051.

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Le virus de la fièvre catarrhale ovine (Bluetongue virus, BTV) est un orbivirus de la famille des Reoviridae. Il comprend 24 sérotypes et il est responsable d’une maladie hémorragique transmise par des insectes chez les ruminants, qui génère des pertes économiques importantes dans le monde entier. La sévérité de la maladie et la durée de la virémie varient entre sérotypes et hôtes du BTV. La réponse innée pourrait être impliquée dans la sensibilité de l’hôte à l’infection mais elle est très peu connue. Pour aborder l’étude de cette réponse innée chez l’hôte, nous avons étudié la dissémination
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Lankester, Felix John. "The impact and control of malignant catarrhal fever in Tanzania." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7769/.

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Malignant Catarrhal Fever (MCF), an often-lethal infectious disease, presents as a variable complex of lesions in susceptible ungulate species. The disease is caused by a -herpesvirus following transmission from an inapparent carrier host. Two major epidemiological forms exist: wildebeest-associated MCF (WA-MCF), in which the virus is transmitted to susceptible species by wildebeest calves less than approximately four months of age, and sheepassociated MCF (SA-MCF) in which the virus is spread by sheep (primarily adolescents). Due to the lack of an in-vitro propagation system for the causative
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43

Kumati, Osama B. Mohamed. "Virus life cycle and the parthenogenesis of malignant catarrhal fever." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/38034/.

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Malignant catarrhal fever (MCF) is caused by two closely associated gamma herpes viruses namely alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 (OvHV-2) and characterised with lymphocyte infiltration in non-lymphoid tissues, vasculitis and epithelial damage. The mechanism by which the viruses cause the disease is not fully understood. The hypothesis of this project was that MCF is initiated by aberrant gene expression in endothelium, epithelium and infected T cells of susceptible animals, because they are not the natural hosts for the viruses and the viruses will not have evolved in
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Schock, Alexandra. "Characterisation of the T-cell proliferation in malignant catarrhal fever." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/29987.

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Malignant catarrhal fever (MCF) is a lethal lymphoproliferative disorder of cattle and deer caused by infection with either Alcelaphine Herpesvirus-1 (AHV-1) or Ovine Herpesvirus - 2 (OHV-2). It was proposed that the viruses induce an interleukin-2 (IL-2) hyperproduction which is responsible for the lymphoid cell hyperplasia observed. The hyperplasia of lymph node cells was investigated by examining the growth characteristics of freshly explanted lymph node cells from AHV-1 infected rabbits. The lymph node cells had a higher thymidine uptake respective to control cultures in the first 24 hours
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Chauveau, Emilie. "Etude des mécanismes d'induction et de contrôle de la production d'interféron par le virus de la Bluetongue dans les cellules non-hématopoïétiques." Paris 7, 2012. http://www.theses.fr/2012PA077235.

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La fièvre catarrhale ovine est une maladie hémorragique sévère chez les ruminants, transmise par des moucherons, les Culicoides. L'agent étiologique de cette maladie est le virus de la langue bleue, pour Bluetongue virus (BTV) en anglais. C'est un virus à ARN double brin (ARNdb), appartenant au genre Orbivirus au sein de la famille des Reoviridae. Depuis longtemps, il a été montré que le BTV induit la production d'interféron. Cependant les récepteurs cellulaires et la voie de signalisation impliqués dans cette production restent inconnus. Le but de ce projet est de les identifier et d'évaluer
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Perrin, Aurélie Anne. "Contribution au développement de vaccins capripoxviraux recombinants contre la fièvre catarrhale ovine." Montpellier 2, 2007. http://www.theses.fr/2007MON20134.

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La Fièvre Catarrhale Ovine est une maladie infectieuse, virale, non contagieuse affectant les ruminants domestiques et sauvages. L'importance économique de cette maladie est liée d'une part aux pertes directes (mortalité, avortements) et indirectes (mauvaise qualité de la laine, retard de croissance) observées sur les animaux infectés et d'autre part au blocage des frontières limitant les exportations. Le virus de la FCO appartient à la famille des Reoviridae et au genre Orbivirus. Il est transmis essentiellement par des moucherons hématophages du genre Culicoides (Diptera: Ceratopogonidae). I
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47

Courtejoie, Noémie. "Modélisation de la dynamique et du contrôle de la fièvre catarrhale ovine en France." Thesis, Paris Est, 2019. http://www.theses.fr/2019PESC0013.

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Le sérotype 8 du virus de la fièvre catarrhale ovine (BTV-8) s’est largement propagé en France en 2007/09 et a eu un fort impact économique. La vaccination, d’abord obligatoire puis facultative, a permis de recouvrer un statut indemne fin 2012, mais l’épizootie a repris en 2015. Il est possible que le BTV-8 n’ait jamais cessé de circuler. Cette thèse visait à clarifier l’épidémiologie du BTV-8 de l’émergence à la réémergence et à apporter une analyse critique des modalités de surveillance et de contrôle, à l’aide de méthodes variées de modélisation. Par des analyses de facteurs de risque, nous
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48

Villard, Pierre. "Évaluation de l'impact et de l'efficacité de la surveillance et de la lutte de la fièvre catarrhale ovine en France." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1351.

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Le sérotype 8 du virus de la fièvre catarrhale ovine (FCO) avait eu un fort impact économique sur la filière bovine lors de l’épizootie entre 2006 et 2009 en France. Les travaux établis au cours de cette thèse visaient à évaluer l’impact financier de la circulation de la FCO après sa réémergence en 2015, et à apporter des éclairages nouveaux sur la dynamique des Culicoides, et sur les mesures de surveillance et de lutte. Par la récolte et l’analyse de données, nous avons pu calculer le coût des mesures de surveillance de septembre 2015 à décembre 2016 (14,6 M€ HT). Grâce à l’analyse des donnée
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49

Bouet-Cararo, Coraline. "Evaluation d'un vaccin recombinant dérivé d'adénovirus canin chez le mouton : application à la fièvre catarrhale ovine (FCO)." Paris 11, 2010. http://www.theses.fr/2010PA114846.

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La Fièvre Catarrhale Ovine est due à un virus affectant les ruminants. Les vaccins actuellement disponibles (atténués ou inactivés) ne permettent pas, ou peu, de protection croisée entre les 24 sérotypes identifiés. Notre travail de thèse a consisté à développer chez le mouton des vaccins recombinants dérivés d’adénovirus canin de type 2 capables d’induire une protection contre un maximum de sérotypes<br>Bluetongue is a viral disease that affects Ruminants. Present vaccines (which are attenuated or inactivated vaccines) do not achieve complete cross protection against the 24 serotypes of the B
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Levy, Claire Safrai. "Identification and characterization of ovine herpesvirus 2 microRNAs." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6468.

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Ovine herpesvirus 2 (OvHV-2) is the causative agent of sheep-associated malignant catarrhal fever (MCF) in susceptible ruminants. Through an unknown mechanism, presence of the virus leads to proliferation of NK-like T cells that are not targetrestricted by the MHC class molecules. These host cells cause the symptoms found in MCF; fever, swollen lymph nodes, and necrotic lesions of the nasal, conjunctival, and oral mucosa, which usually leads to death of the host. MicroRNAs (miRNAs) are ~22 nt RNA molecules expressed by eukaryotes and viruses that regulate genes post-transcriptionally. Viral mi
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