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Artykuły w czasopismach na temat "Chandrasekaran's approach"

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Finn, Donal P. "A physical modeling assistant for the preliminary stages of finite element analysis." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 7, no. 4 (1993): 275–86. http://dx.doi.org/10.1017/s0890060400000366.

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This paper describes work in progress aimed at developing an interactive modeling tool that assists engineers with the task of physical modeling in finite element analysis. Physical modeling precedes the numerical simulation phase of finite element analysis and involves applying modeling idealizations to real world physical systems so that complex engineering problems are more amenable to numerical computation. In the paper, the nature of physical modeling is explored, a cognitive model of how engineers are thought to model complex problems is described and based on this model a knowledge-base
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Borgo, Stefano, Massimiliano Carrara, Pawel Garbacz, and Pieter E. Vermaas. "A formal ontological perspective on the behaviors and functions of technical artifacts." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 23, no. 1 (2008): 3–21. http://dx.doi.org/10.1017/s0890060409000079.

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AbstractIn this paper we present a formal characterization of the engineering concepts of behavior and function of technical artifacts. We capture the meanings that engineers attach to these concepts by formalizing, within the formal ontology DOLCE, the five meanings of artifact behavior and the two meanings of function that Chandrasekaran and Josephson identified in 2000 within the functional representation approach. We begin our formalization by reserving the term “behavior” of a technical artifact as “the specific way in which the artifact occurs in an event.” This general notion is charact
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Saran, Uttara, Balaji Chandrasekaran, Ashish Tyagi, et al. "Abstract 1527: Developing a multifaceted approach to target androgen receptor (AR) in castration resistant prostate cancer." Cancer Research 82, no. 12_Supplement (2022): 1527. http://dx.doi.org/10.1158/1538-7445.am2022-1527.

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Abstract Androgen receptor (AR) signaling is also regulated epigenetically by histone-modifying enzymes (histone deacetylases-HDACs) that result in the development and progression of prostate cancer (CaP). It has been established that the inhibition of HDACs suppresses CaP proliferation by inhibiting AR signaling via multiple mechanisms, including AR degradation. Hence, the goal of this study was to develop small molecules that employ multiple mechanisms to inhibit AR expression and promote its degradation, which would effectively control the emergence and treatment of castration-resistant pro
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Johnson, Delna, Sivapriya Kirubakaran, and Vijay Thiruvenkatam. "Abstract C154: Investigation of indole-based molecules as a new class of TLK1 inhibitors in prostate cancer therapy." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): C154. http://dx.doi.org/10.1158/1535-7163.targ-23-c154.

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Abstract Targeting protein kinases is an attractive strategy in cancer therapy owing to their importance in cell signaling pathways. Tousled-like kinases (TLKs) are associated with chromosomal integrity, DNA replication, and repair. However, the dysregulation of these genes can give rise to different aberrations. The activity of TLK1, a human isoform of TLK, is found to be attenuated in the case of prostate cancer and breast cancer, as it can phosphorylate many proteins of the DNA Damage Response (DDR) pathway, hence making TLK1 a novel druggable target. To date, phenothiazines-which are known
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Belew, Muluken S., Richard Carpenedo, Alessia Pallaoro та ін. "Abstract 39: Preclinical in vitro and in vivo evaluation of CD8αβ+ CD19 CAR iPSCs T cells generated in a TCR signal-independent manner using DLL4/VCAM-coupled microbeads". Cancer Research 84, № 6_Supplement (2024): 39. http://dx.doi.org/10.1158/1538-7445.am2024-39.

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Abstract The use of clonally-derived, induced pluripotent stem cells (iPSCs) as starting material for therapeutic T cell manufacturing would overcome many limitations of autologous Chimeric Antigen Receptor T cell (CAR-T) therapies. Complex, multi-stage genome engineering, large batch production and rigorous lot testing could provide a consistent source of off-the-shelf, functionally enhanced T cell products. However, this vision cannot be realized using existing T cell differentiation platforms, which fail to present Notch ligands with the precision and intensity required to control T cell di
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Kasi, Anup, Michael Birrer, Jason Brown, et al. "Abstract B017: Phase 2 Study of NP-G2-044, a Novel Fascin Inhibitor, in Combination with Anti-PD-1 Therapy in Patients with Solid Tumors Resistant to Prior Anti-PD-1 Therapy." Cancer Immunology Research 13, no. 2_Supplement (2025): B017. https://doi.org/10.1158/2326-6074.io2025-b017.

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Abstract NP-G2-044 is a first-in-class novel fascin inhibitor that targets fascin proteins in both tumor cells and intratumoral dendritic cells (DCs). Fascin, the primary actin-bundling protein plays a critical role in cell migration and tumor metastasis. NP-G2-044 blocks tumor metastasis, reduces tumor growth, and activates intratumoral DCs by enhancing antigen uptake and increasing the population of activated DCs leading to the proliferation of CD8+ T cells. NP-G2-044 is an oral first-in-class anti-metastasis agent and simultaneously synergizes with ICIs to enhance anti-tumor immune response
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K K A, Abdullah, Robert A B C, and Adeyemo A B. "August 2016 VOLUME 5, ISSUE 8, AUGUST 2016 5th Generation Wi-Fi Shatha Ghazal, Raina S Alkhlailah Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5801 ECG Arrhythmia Detection Using Choi-Williams Time-Frequency Distribution and Artificial Neural Network Sanjit K. Dash, G. Sasibhushana Rao Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5802 Data Security using RSA Algorithm in Cloud Computing Santosh Kumar Singh, Dr. P.K. Manjhi, Dr. R.K. Tiwari Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5803 Detection Algorithms in Medical Imaging Priyanka Pareek, Pankaj Dalal Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5804 A Review Study on the CPU Scheduling Algorithms Shweta Jain, Dr. Saurabh Jain Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5805 Healthcare Biosensors - A Paradigm Shift To Wireless Technology Taha Mukhtar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5806 Congestion Control for Peer to Peer Application using Random Early Detection Algorithm Sonam Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5807 Quantitative and Qualitative Analysis of Milk Parameters using Arduino Controller Y.R. Bhamare, M.B. Matsagar, C.G. Dighavkar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5808 Ardunio Based Security and Safety using GSM as Fault Alert System for BTS (Base Transceiver Station) Umeshwari Khot, Prof. Venkat N. Ghodke Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5809 Automatic Single and Multi Topic Summarization and Evolution to Generate Timeline Mrs. V. Meenakshi, Ms. S. Jeyanthi Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5810 Data Hiding in Encrypted HEVC/AVC Video Streams Saltanat Shaikh, Prof. Shahzia Sayyad Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5811 A Study of Imbalanced Classification Problem P. Rajeshwari, D. Maheshwari Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5812 Design of PTL based Area Efficient and Low Power 4-bit ALU Saraabu Narendra Achari, Mr. C. Pakkiraiah Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5813 The Design of Driver Safety Awareness and Assistance System through Sleep Activated and Auto Brake System for Vehicle Control D. Sivabalaselvamani, Dr. A. Tamilarasi, L. Rahunathan and A.S. Harishankher Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5814 Parameters Selection, Applications & Convergence Analysis of PSO Algorithms Sachin Kumar, Mr. N.K. Gupta Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5815 Effective Pattern Deploying Model for the Document Restructuring and Classification Niketa, Jharna Chopra Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5816 Cataloging Telugu Sentences by Hidden Morkov Techniques V. Suresh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5817 Biometrics for Cell Phone Safety Jyoti Tiwari, Santosh Kumar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5818 Digital Image Watermarking using Modified DWT&DCT Combination and Bi Linear Interpolation Yannam .Nagarjuna, K. Chaitanya Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5819 Comparative Study and Analysis on the Techniques of Web Mining Dipika Sahu, Yamini Chouhan Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5820 A Review of MIL-STD-1553 Bus Trends and Future K. Padmanabham, Prabhakar Kanugo, Dr. K. Nagabhushan Raju, M. Chandrashekar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5821 Design of QPSK Digital Modulation Scheme Using Turbo Codes for an Air Borne System D. Sai Brunda, B. Geetha Rani Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5822 An Efficient Locally Weighted Spectral Cluster for Automatic Image Segmentation Vishnu Priya M, J Santhosh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5823 An Efficient Sliding Window Based Micro Cluster Over Data Streams Nancy Mary, A. Venugopal Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5824 Comparative Analysis of Traditional Frequency Reuse Techniques in LTE Network Neelam Rani, Dr. Sanjeev Kumar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5825 Score Level Integration of Fingerprint and Hand Geometry Biometrics Jyoti Tiwari, Santosh Kumar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5826 CHARM: Intelligently Cost and Bandwidth Detection for FTP Servers using Heuristic Algorithm Shiva Urolagin Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5827 Image Enhancement Using Modified Exposure Based Histogram SK. Nasreen, N. Anupama Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5828 Human Gesture Based Recognition and Classification Using MATLAB Suman, Er. Kapil Sirohi Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5829 Image Denoising- A Novel Approach Dipali D. Sathe, Prof. K.N. Barbole Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5830 Design of Low Pass Digital FIR Filter Using Nature Inspired Technique Nisha Rani, Balraj Singh, Darshan Singh Sidhu Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5831 Issues and Challenges in Software Quality Assurance Himangi, Surender singh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5832 Hybridization of GSA and AFSA to Detect Black Hole Attack in Wireless Sensor Network Soni Rani, Charanjit Singh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5833 Reversible Watermarking Technique for Data Hiding, Accurate Tamper Detection in ROI and Exact Recovery of ROI Y. Usha Madhuri, K. Chaitanya Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5834 Fault Tolerance and Concurrency Control in Heterogeneous Distributed Database Systems Sagar Patel, Meghna Burli, Nidhi Shah, Prof. (Mrs.) Vinaya Sawant Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5835 Collection of Offline Tamil Handwriting Samples and Database Creation D. Rajalakshmi, Dr. S.K. Jayanthi Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5836 Overview of Renewable Energy in Maharashtra Mr. Sagar P. Thombare, Mr. Vishal Gunjal, Miss. Snehal Bhandarkar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5837 Comparative Analysis of Efficient Image Steganographic Technique with the 2-bit LSB Algorithm for Color Images K. S. Sadasiva Rao, Dr A. Damodaram Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5838 An Efficient Reverse Converter Design for Five Moduli Set RNS Y. Ayyavaru Reddy, B. Sekhar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5839 VLSI Design of Area Efficient High Performance SPMV Accelerator using VBW-CBQCSR Scheme N. Narasimharao, A. Mallaiah Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5840 Customer Retention of MCDR using 3SCDM Approaches Suban Ravichandran, Chandrasekaran Ramasamy Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5841 User Privacy and Data Trustworthiness in Mobile Crowd Sensing Ms. T. Sharadha, Dr. R. Vijaya Bhanu Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5842 A Safe Anti-Conspiracy Data Model For Changing Groups in Cloud G. Ajay Kumar, Devaraj Verma C Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5843 Scope and Adoption of M-Commerce in India Anurag Mishra, Sanjay Medhavi, Khan Shah Mohd, P.C. Mishra Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5844 A Secure Data Hiding Scheme For Color Image Mrs. S.A. Bhavani Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5845 A Study of Different Content Based Image Retrieval Techniques C. Gururaj, D. Jayadevappa, Satish Tunga Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5846 Cache Management for Big Data Applications: Survey Kiran Grover, Surender Singh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5847 Survey on Energy Efficient Protocols and Challenges in IOT Syeda Butool Fatima, Sayyada Fahmeeda Sultana, Sadiya Ansari Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5848 Educational Data Mining For Evaluating Students Performance Sampreethi P.K, VR. Nagarajan Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5849 Iterative Pareto Principle for Software Test Case Prioritization Manas Kumar Yogi, G. Vijay Kumar, D. Uma Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5850 Localization Techniques in Wireless Sensor Networks: A Review Abhishek Kumar, Deepak Prashar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5851 Ensemble Averaging Filter for Noise Reduction Tom Thomas Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5852 Survey Paper on Get My Route Application Shubham A. Purohit, Tushar R. Khandare, Prof. Swapnil V. Deshmukh Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5853 Design and Implementation of Smart Car with Self-Navigation and Self-Parking Systems using Sensors and RFID Technology Madhuri M. Bijamwar, Prof. S.G. Kole, Prof. S.S. Savkare Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5854 Comparison Study of Induction Motor Drives using Microcontroller and FPGA Sooraj M S, Sreerag K T V Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5855 A Survey on Text Categorization Senthil Kumar B, Bhavitha Varma E Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5856 Multirate Signal Reconstruction Using Two Channel Orthogonal Filter Bank Sijo Thomas, Darsana P Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5857 The Multi-keyword Synonym Search for Encrypted Cloud Data Using Clustering Method Monika Rani H G, Varshini Vidyadhar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5858 A Review on Various Speech Enhancement Techniques Alugonda Rajani, Soundarya .S.V.S Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5859 A Survey on Various Spoofing Attacks and Image Fusion Techniques Pravallika .P, Dr. K. Satya Prasad Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5860 Non-Invasive Vein Detection using Infra-red Rays Aradhana Singh, Dr. S.C. Prasanna Kumar, Dr. B.G. Sudershan Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5861 Boundary-Polygons for Minutiae based Fingerprinst Recognition Kusha Maharshi, Prashant Sahai Saxena Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5862 Image Forgery Detection on Digital Images Nimi Susan Saji, Ranjitha Rajan Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5863 Enhancing Information Security in Big Data Renu Kesharwani Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5864 Secure Multi-Owner Data Sharing for Dynamic Groups in Cloud Ms. Nilophar M. Masuldar, Prof. V. P. Kshirsagar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5865 Compact Microstrip Octagonal Slot Antenna for Wireless Communication Applications Thasneem .H, Midhun Joy Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5866 ‘Aquarius’- Smart IOT Technology for Water Level Monitoring System Prof. A. M. Jagtap, Bhaldar Saniya Sikandar, Shinde Sharmila Shivaji, Khalate Vrushali Pramod, Nirmal Kalyani Sarangdhar Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5867 Future of Results in Select Search Engine Peerzada Mohammad Iqbal, Dr. Abdul Majid Baba, Aasim Bashir Abstract | PDF with Text | DOI: 10.17148/IJARCCE.2016.5868 Semantic Indexing Techniques on Information Retrieval of Web Content." IJARCCE 5, no. 8 (2016): 347–52. http://dx.doi.org/10.17148/ijarcce.2016.5869.

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Chandrasekaran, Maharajan. "A SAFE AND EFFECTIVE SUPRAHYOID SURGICAL APPROACH FOR LINGUAL THYROID." Otolaryngology online, June 19, 2017. https://doi.org/10.5281/zenodo.812070.

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Lingual thyroid is an uncommon disorder which rarely need surgical intervention. Various tech- niques have been described with the majority requiring morbid procedures. We sought to describe a relatively novel technique for the surgical approach of this uncommon disorder with negligible morbidity and good functional results. The suprahyoid surgical approach for lingual thyroid was undertaken in a 27 year old lady with persistent dysphagia after thyroxine suppression therapy. The procedure was accomplished in 40 minutes with minimal blood loss and does not require morbid procedures like splitti
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Wang, Minjie, and Genevera I. Allen. "Thresholded Graphical Lasso Adjusts for Latent Variables." Biometrika, November 10, 2022. http://dx.doi.org/10.1093/biomet/asac060.

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SUMMARY Structural learning of Gaussian graphical models in the presence of latent variables has long been a challenging problem. Chandrasekaran et al. (2012) proposed a convex program to estimate a sparse graph plus low-rank term that adjusts for latent variables; but, this approach poses challenges from both a computational and statistical perspective. We propose an alternative and incredibly simple solution: apply a hard thresholding operator to existing graph selection methods. Conceptually simple and computationally attractive, we show that thresholding the graphical lasso is graph select
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Chandrasekaran, Karthekeyan, and Chandra Chekuri. "Hypergraph k-Cut for Fixed k in Deterministic Polynomial Time." Mathematics of Operations Research, March 22, 2022. http://dx.doi.org/10.1287/moor.2021.1250.

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We consider the Hypergraph-k-Cut problem. The input consists of a hypergraph [Formula: see text] with nonnegative hyperedge-costs [Formula: see text] and a positive integer k. The objective is to find a minimum cost subset [Formula: see text] such that the number of connected components in G – F is at least k. An alternative formulation of the objective is to find a partition of V into k nonempty sets [Formula: see text] so as to minimize the cost of the hyperedges that cross the partition. Graph-k-Cut, the special case of Hypergraph-k-Cut obtained by restricting to graph inputs, has received
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Streszczenia konferencji na temat "Chandrasekaran's approach"

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Finn, D. P., J. B. Grimson, and N. M. Harty. "An Intelligent Mathematical Modelling Assistant for Analysis of Physical Systems." In ASME 1992 International Computers in Engineering Conference and Exposition. American Society of Mechanical Engineers, 1992. http://dx.doi.org/10.1115/cie1992-0092.

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Abstract This paper describes work in progress aimed at developing an intelligent modelling assistant for the mathematical modelling task associated with engineering analysis. Mathematical modelling precedes detailed numerical analysis and involves formulating and evaluating engineering problems with the objective of proposing a candidate mathematical model that meets desired modelling requirements. The approach taken in this work is based on Chandrasekaran’s proposecritique-modify method which is adapted for modelling. The use of this paradigm is justified by viewing the mathematical modellin
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