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1

Ichinomiya, Masayuki, Emi Yamada, Shuichi Yamashita, Akinori Ohta, and Hiroyuki Horiuchi. "Class I and Class II Chitin Synthases Are Involved in Septum Formation in the Filamentous Fungus Aspergillus nidulans." Eukaryotic Cell 4, no. 6 (2005): 1125–36. http://dx.doi.org/10.1128/ec.4.6.1125-1136.2005.

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ABSTRACT The class II and class I chitin synthases of the filamentous fungus Aspergillus nidulans are encoded by chsA and chsC, respectively. Previously, we presented several lines of evidence suggesting that ChsA and ChsC have overlapping functions in maintaining cell wall integrity. In order to determine the functions of these chitin synthases, we employed electron and fluorescence microscopy and investigated in detail the cell wall of a ΔchsA ΔchsC double mutant (ΔAC mutant) along with the localization of ChsA and ChsC. In the lateral cell wall of the ΔAC mutant, electron-transparent region
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Rantsatsi, Ndaleni Phinias, Innocent Musonda, and Justus Agumba. "Factors that determine construction health and safety agent collaboration on construction projects: A Delphi study." Acta Structilia 28, no. 2 (2021): 53–77. http://dx.doi.org/10.18820/24150487/as28i2.3.

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The construction industry (CI) continues to be the cause of injuries and illnesses to many workers worldwide. Collaboration between the construction health and safety agent (CHSA) and other built environment professionals may improve the impact of the CHSA on health and safety (H&S) performance. However, no study has identified the factors that determine CHSA collaboration on construction sites. A three rounds Delphi study was conducted to identify the factors that determine CHSA collaboration. A panel of 14 experts serving the CI were selected from four continents and were asked to identi
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Guan, Song, Zhang, et al. "An Effective Cationic Human Serum Albumin-based Gene-Delivery Carrier Containing the Nuclear Localization Signal." Pharmaceutics 11, no. 11 (2019): 608. http://dx.doi.org/10.3390/pharmaceutics11110608.

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Considerable effort has been devoted to the development of gene carriers over the years. However, toxicity, immunogenicity, and low transfection efficiency are still major barriers. How to overcome these obstacles has become a burning question in gene delivery. In the present study, a simple cationic human serum albumin (CHSA)-based gene-delivery system containing nuclear localization signals (NLSs) was constructed to conquer the limitations. CHSA/NLS/plasmid DNA (pDNA) complexes were prepared and characterized by Hoechst 33258 intercalation, gel retardation assay, morphological analysis, circ
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Rantsatsi, Ndaleni Phinias, Innocent Musonda, and Justus Agumba. "Construction Health and Safety Agent Collaboration and Its Influence on Health and Safety Performance in the South African Construction Industry." Safety 9, no. 1 (2023): 8. http://dx.doi.org/10.3390/safety9010008.

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Fatalities, injuries, and illnesses continue to occur in the construction industry (CI), despite efforts made by clients, designers, and contractors. The lack of collaboration between these project actors and construction health and safety agents (CHSA) remains a challenge for both construction professionals and academics. Given the urgent need for CHSA to collaborate with other construction project members, this study proposes a model for improving CHSA collaboration and its influence on health and safety (H&S) performance. The exploratory sequential mixed method, which included a Delphi
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Berleman, James E., Benjamin M. Hasselbring, and Carl E. Bauer. "Hypercyst Mutants in Rhodospirillum centenum Identify Regulatory Loci Involved in Cyst Cell Differentiation." Journal of Bacteriology 186, no. 17 (2004): 5834–41. http://dx.doi.org/10.1128/jb.186.17.5834-5841.2004.

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ABSTRACT Rhodospirillum centenum is a purple photosynthetic bacterium that forms resting cyst cells when starved for nutrients. In this study, we demonstrate that chalcone synthase gene (chsA) expression is developmentally regulated, with expression of chsA increasing up to 86-fold upon induction of the cyst developmental cycle. Screening for mini-Tn5-induced mutants that exhibit elevated chsA::lacZ expression has led to the isolation of a set of R. centenum mutants that display increased chsA gene expression concomitant with constitutive induction of the cyst developmental cycle. These “hyper
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6

Zhu, Yunqi, Tong Liu, Yingsi Wang, et al. "ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in Aspergillus niger." Journal of Fungi 9, no. 8 (2023): 801. http://dx.doi.org/10.3390/jof9080801.

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Chitin synthases (CHSs) are vital enzymes for the synthesis of chitin and play important and differential roles in fungal development, cell wall integrity, environmental adaptation, virulence, and metabolism in fungi. However, except for ChsC, a class III CHS, little is known about the functions of CHSs in Aspergillus niger, an important fungus that is widely applied in the fermentation industry and food processing, as well as a spoilage fungus of food and a human pathogen. This study showed the important functions of ChsA, a class II CHS, in A. niger using multi-phenotypic and transcriptional
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Colombi, Chiara, Giacomo Dacarro, Yuri Antonio Diaz Fernandez, Angelo Taglietti, Piersandro Pallavicini, and Lavinia Doveri. "Human Serum Albumin Protein Corona in Prussian Blue Nanoparticles." Nanomaterials 14, no. 16 (2024): 1336. http://dx.doi.org/10.3390/nano14161336.

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Prussian Blue nanoparticles (PBnps) are now popular in nanomedicine thanks to the FDA approval of PB. Despite the numerous papers suggesting or describing the in vivo use of PBnps, no studies have been carried out on the formation of a protein corona on the PBnp surface and its stabilizing role. In this paper, we studied qualitatively and quantitatively the corona formed by the most abundant protein of blood, human serum albumin (HSA). Cubic PBnps (41 nm side), prepared in citric acid solution at PB concentration 5 × 10−4 M, readily form a protein corona by redissolving ultracentrifuged PBnp p
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8

O'Laughlen, Mary, Patricia J. Hollen, Karen Rance, et al. "Extending the AAP Health-Related Quality of Life Measure (CHSA-C) to Older Adolescents (CHSA-T)." Journal of Pediatric Health Care 29, no. 4 (2015): 313–14. http://dx.doi.org/10.1016/j.pedhc.2015.04.005.

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9

Fisher, Grace S., Erin Bradley, Diane Costulas, et al. "Home Modification Outcomes in the Residences of Older People as a Result of Cougar Home Safety Assessment (Version 4.0) Recommendations." Californian Journal of Health Promotion 6, no. 1 (2008): 87–110. http://dx.doi.org/10.32398/cjhp.v6i1.1295.

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The purpose of this study was to determine if recommendations made as a result of the administration of the Cougar Home Safety Assessment Version 4.0 (CHSA 4.0) were effective in causing older residents to make environmental safety modifications in their homes. Initial data were collected during the administration of the CHSA 4.0 in the homes of 40 older people in four northeastern states. After completing the initial assessments, the researchers provided the participants with recommendations for improving the environmental safety of their homes. Approximately one month later, each home was re
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10

Orzełek, Ariel. "Internal Crisis in the Christian Social Association in the 1960s and the Political Fall of Jan Frankowski." Res Historica 56 (December 21, 2023): 969–94. http://dx.doi.org/10.17951/rh.2023.56.969-994.

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This article presents the history of an internal crisis in the Christian Social Association (ChSA) in the 1960s, which led to the political downfall of its founder and first leader, Jan Frankowski, in 1968. The genesis of the events is presented, connected with the group’s dissatisfaction with the activities of the president, expressed both by the members of the CHSA and its political supervisors, as well as with the influence of the agents branched in the Association and the political conditions related to the crisis of 1968 in the People's Republic of Poland. Attention was also paid to the c
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11

Xu, Xuemei, Shiqi Fang, Yuan Zhuang, et al. "Cationic Albumin Encapsulated DNA Origami for Enhanced Cellular Transfection and Stability." Materials 12, no. 6 (2019): 949. http://dx.doi.org/10.3390/ma12060949.

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DNA nanostructures, owing to their controllable and adaptable nature, have been considered as highly attractive nanoplatforms for biomedical applications in recent years. However, their use in the biological environment has been restricted by low cellular transfection efficiency in mammalian cells, weak stability under physiological conditions, and endonuclease degradation. Herein, we demonstrate an effective approach to facilitate fast transfection of DNA nanostructures and enhance their stability by encapsulating DNA origami with a biocompatible cationic protein (cHSA) via electrostatic inte
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12

Lee, Jeong Im, Jeong Hwan Choi, Bum Chan Park, et al. "Differential expression of the chitin synthase genes of Aspergillus nidulans, chsA, chsB, and chsC, in response to developmental status and environmental factors." Fungal Genetics and Biology 41, no. 6 (2004): 635–46. http://dx.doi.org/10.1016/j.fgb.2004.01.009.

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13

Dunn, Joanna. "Richard Rodney Bennett’s ‘The Mines of Sulphur’." Tempo 60, no. 235 (2006): 33–34. http://dx.doi.org/10.1017/s0040298206220047.

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14

Clarke, Philippa J., Victor W. Marshall, Carol D. Ryff, and Blair Wheaton. "Measuring Psychological Well-Being in the Canadian Study of Health and Aging." International Psychogeriatrics 13, S1 (2001): 79–90. http://dx.doi.org/10.1017/s1041610202008013.

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The Canadian Study of Health and Aging (CHSA) provided an opportunity to examine the positive aspects of aging. CHSA-2 included the 18-item Ryff multidimensional measure of well-being, which taps six core theoretical dimensions of positive psychological functioning. The measure was administered to 4,960 seniors without severe cognitive impairment or dementia at CSHA-2. Intercorrelations across scales were generally low. At the same time, the internal consistency reliability of each of the 6 subscales was not found to be high. Confirmatory factor analyses provide support for a 6-factor model, a
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15

Saravolatz, Stephanie N., Hayley Martin, Joan Pawlak, Leonard B. Johnson, and Louis D. Saravolatz. "Ceftaroline-Heteroresistant Staphylococcus aureus." Antimicrobial Agents and Chemotherapy 58, no. 6 (2014): 3133–36. http://dx.doi.org/10.1128/aac.02685-13.

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ABSTRACTHeteroresistance refers to the presence, within a large population of antimicrobial-susceptible microorganisms, of subpopulations with lesser susceptibilities. Ceftaroline is a novel cephalosporin with activity against methicillin-resistantStaphylococcus aureus(MRSA). The aim of this study was to detect the prevalence of ceftaroline heteroresistancein vitroin a select group ofS. aureusstrains. There were 57 isolates selected for evaluation, 20 MRSA, 20 vancomycin-intermediateS. aureus(VISA), 7 daptomycin-nonsusceptibleS. aureus(DNSSA), 6 linezolid-nonsusceptibleS. aureus(LNSSA), and 4
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16

Choi, W. J., B. Santos, A. Durán, and E. Cabib. "Are yeast chitin synthases regulated at the transcriptional or the posttranslational level?" Molecular and Cellular Biology 14, no. 12 (1994): 7685–94. http://dx.doi.org/10.1128/mcb.14.12.7685-7694.1994.

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The three chitin synthases of Saccharomyces cerevisiae, Chs1, Chs2, and Chs3, participate in septum and cell wall formation of vegetative cells and in wall morphogenesis of conjugating cells and spores. Because of the differences in the nature and in the time of execution of their functions, the synthases must be specifically and individually regulated. The nature of that regulation has been investigated by measuring changes in the levels of the three synthases and of the messages of the three corresponding genes, CHS1, CHS2, and CAL1/CSD2/DIT101/KTI2 (referred to below as CAL1/CSD2), during t
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17

Choi, W. J., B. Santos, A. Durán, and E. Cabib. "Are yeast chitin synthases regulated at the transcriptional or the posttranslational level?" Molecular and Cellular Biology 14, no. 12 (1994): 7685–94. http://dx.doi.org/10.1128/mcb.14.12.7685.

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The three chitin synthases of Saccharomyces cerevisiae, Chs1, Chs2, and Chs3, participate in septum and cell wall formation of vegetative cells and in wall morphogenesis of conjugating cells and spores. Because of the differences in the nature and in the time of execution of their functions, the synthases must be specifically and individually regulated. The nature of that regulation has been investigated by measuring changes in the levels of the three synthases and of the messages of the three corresponding genes, CHS1, CHS2, and CAL1/CSD2/DIT101/KTI2 (referred to below as CAL1/CSD2), during t
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18

Campos, Margarida de Cássia, and Marleide Rodrigues da Silva Perrude. "Educação decolonial e antirracista na BNCC do Ensino Médio da área de Ciências Humanas e Sociais Aplicadas." Revista e-Curriculum 23 (May 30, 2025): e64644. https://doi.org/10.23925/1809-3876.2025v23e64644.

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O presente texto discute os desafios da educação decolonial e antirracista no contexto das políticas públicas pós-meados de 2016, a partir da seguinte indagação: Quais as perspectivas da Base Nacional Comum Curricular (BNCC) do Ensino Médio, na área de Ciências Humanas e Sociais Aplicadas (CHSA), para uma educação decolonial e antirracista? Para tanto, foi realizado um estudo teórico-bibliográfico, seguido de uma análise qualitativa do texto introdutório e das habilidades prescritas na BNCC-CHSA (Ensino Médio). O referencial bibliográfico contextualiza, inicialmente, os avanços nas legislações
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19

Samarasinghe, AIP, SM Arnold, and Pushpa Fonseka. "Validation of modified Children's Health Survey for Asthma (CHSA) Questionnaire for the Sri Lankan setting." INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS 05, no. 05 (2022): 949–55. https://doi.org/10.5281/zenodo.6553713.

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Asthma is one of the most common chronic diseases in the childhood in developing and developed countries. Health related quality of life has become essential part of health outcome measurement in chronic disorders. The present study was conducted to assess the validity and reliability of western developed scale for use in Sri Lankan children and their care givers. This study was a hospital based cross sectional study for validation of the western developed CHSA questionnaire. Study population was 100 children who was diagnosed as having asthma. Factor analysis of the data in the present study
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20

Ichinomiya, Masayuki, Hiroyuki Horiuchi, and Akinori Ohta. "Different functions of the class I and class II chitin synthase genes, chsC and chsA, are revealed by repression of chsB expression in Aspergillus nidulans." Current Genetics 42, no. 1 (2002): 51–58. http://dx.doi.org/10.1007/s00294-002-0329-4.

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Chen, X., H. Tian, L. Zou, B. Tang, J. Hu, and W. Zhang. "Disruption of Spodoptera exigua larval development by silencing chitin synthase gene A with RNA interference." Bulletin of Entomological Research 98, no. 6 (2008): 613–19. http://dx.doi.org/10.1017/s0007485308005932.

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AbstractRNA interference (RNAi) is a powerful tool for rapidly analyzing gene functions. However, little is known about the possible use of dsRNA/siRNA as a pest control method. Here, we demonstrate that dsRNA/siRNA can induce the silence of chitin synthase gene A (CHSA), which is an important gene for the growth and development of cuticles and trachea in beet armyworm, Spodoptera exigua. Based on the in vitro RNAi experiments in an insect cell line (Trichoplusia ni High 5), in vivo RNAi was performed by injecting synthesized dsRNA/siRNA into the 4th instar larvae of S. exigua. Significantly l
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22

Motoyama, T., Makoto Fujiwara, Nobuko Kojima, Hiroyuki Horiuchi, Akinori Ohta, and M. Takagi. "The Aspergillus nidulans genes chsA and chsD encode chitin synthases which have redundant functions in conidia formation." Molecular and General Genetics MGG 253, no. 4 (1997): 520–28. http://dx.doi.org/10.1007/s004380050353.

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Paiva, Andrea Lucia da Silva de. "ANTROPOLOGIA E ENSINO:." Áltera Revista de Antropologia, no. 17 (August 31, 2024): 1–29. https://doi.org/10.22478/ufpb.2447-9837.2024.n17.67462.

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O presente trabalho se centra na abordagem antropológica sobre cultura presente nos materiais didáticos de 2021 aprovados pelo Plano Nacional de Livros Didáticos (PNLD), sob a nova roupagem criada com o Novo Ensino Médio: a área de conhecimento Ciências Humanas e Sociais Aplicadas (CHSA). Segundo a Base Nacional Comum Curricular (BNCC), essa área do conhecimento, integrada por Filosofia, Geografia, História e Sociologia, se volta às seguintes categorias: tempo e espaço, território e fronteiras, indivíduo, natureza, sociedade, cultura, ética, política e trabalho. Descreveremos a parte cultural,
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24

Li, Yan, Youwei Xi, Zhongkai Zhang, Xingqi Huang, and Yi Li. "Co-suppression in transgenicPetunia hybrida expressing chalcone synthase A (chsA)." Science in China Series C: Life Sciences 44, no. 6 (2001): 661–68. http://dx.doi.org/10.1007/bf02879361.

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Zhjeqi, Valbona, Michael Kundi, Mimoza Shahini, Halil Ahmetaj, Luljeta Ahmetaj, and Shaip Krasniqi. "Does Socioeconomic Status Affect Mental Well-being Among Children with Asthma in Kosovo?" International Journal of Biomedicine 13, no. 2 (2023): 286–91. http://dx.doi.org/10.21103/article13(2)_oa16.

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The aim of this study was to investigate the relationship between mental well-being – as assessed by the SDQ among children with asthma in Kosovo and SES. Methods and Results: For this cross-sectional observational study, data were collected from five regions of Kosovo, public and private institutions, public hospitals and primary healthcare facilities in each area, a tertiary level hospital, and two private immunology clinics in the capital city. The survey included 161 Kosovar children (mean age of 11.1±2.7 years) with asthma, aged 7-16 years, and their caregivers. The survey questionnaires
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26

Fei, Xiaowen, Sha Xiao, Xiaodan Huang, et al. "Control of Aedes mosquito populations using recombinant microalgae expressing short hairpin RNAs and their effect on plankton." PLOS Neglected Tropical Diseases 17, no. 1 (2023): e0011109. http://dx.doi.org/10.1371/journal.pntd.0011109.

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New biocontrol strategies are urgently needed to combat vector-borne infectious diseases. This study presents a low-cost method to produce a potential mosquito insecticide that utilizes the microalgae released into suburban water sources to control mosquito populations. Chlorella microalgae are ubiquitous in local waters, which were chosen as the host for genetic transfection. This species facilitated the recombinant algae to adapt to the prevailing environmental conditions with rapid growth and high relative abundance. The procedure involved microalgae RNAi-based insecticides developed using
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Relova, Sharon, Yayuk Joffres, Drona Rasali, Li Rita Zhang, Geoffrey McKee, and Naveed Janjua. "British Columbia’s Index of Multiple Deprivation for Community Health Service Areas." Data 7, no. 2 (2022): 24. http://dx.doi.org/10.3390/data7020024.

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Area-based socio-economic indicators, such as the Canadian Index of Multiple Deprivation (CIMD), have been used in equity analyses to inform strategies to improve needs-based, timely, and effective patient care and public health services to communities. The CIMD comprises four dimensions of deprivation: residential instability, economic dependency, ethno-cultural composition, and situational vulnerability. Using the CIMD methodology, the British Columbia Index of Multiple Deprivation (BCIMD) was developed to create indexes at the Community Health Services Area (CHSA) level in British Columbia
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Pinchai, Nadthanan, B. Zachary Perfect, Praveen Rao Juvvadi, et al. "Aspergillus fumigatus Calcipressin CbpA Is Involved in Hyphal Growth and Calcium Homeostasis." Eukaryotic Cell 8, no. 4 (2009): 511–19. http://dx.doi.org/10.1128/ec.00336-08.

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ABSTRACT Calcineurin is a conserved protein phosphatase that plays a critical role in Ca2+ signaling and stress responses. Previously, a new class of conserved calcineurin-binding proteins, the calcipressins, was identified. However, the role of these proteins remains controversial, and both inhibitory and stimulatory effects on calcineurin were observed. In this study, we investigate the role of CbpA, the Aspergillus fumigatus member of the calcipressin family, and report that deletion of the cbpA gene resulted in reduced hyphal growth and limited attenuated virulence. Interestingly, under hi
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Fisher, Grace, Rebecca Burgess, Haley DiMassimo, et al. "A Best-Practice Modification of the Cougar Home Safety Assessment (CHSA)." American Journal of Occupational Therapy 74, no. 4_Supplement_1 (2020): 7411500042p1. http://dx.doi.org/10.5014/ajot.2020.74s1-po6405.

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Griesbach, R. J., and R. M. Beck. "Sequence Analysis of the Chalcone Synthase Gene Intron in Four Petunia Jussieu Taxa." Journal of the American Society for Horticultural Science 130, no. 3 (2005): 360–65. http://dx.doi.org/10.21273/jashs.130.3.360.

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The sequence of the intron within the chalcone synthase A gene (ChsA) was used to characterize Petunia integrifolia subsp. integrifolia var. depauperata (Fries) Smith et Downs, P. altiplana Ando et Hashimoto, P. littoralis Smith et Downs, and an unknown taxon from the town of Torres in Brazil. Based upon the intron, the Torres taxon most closely resembled P. integrifolia. The unrooted phylogenetic tree suggested that P. integrifolia was more closely related to P. littoralis than P. altiplana.
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Işıkver, Yasemin, and Dursun Saraydın. "Smart Hydrogels: Preparation, Characterization, and Determination of Transition Points of Crosslinked N-Isopropyl Acrylamide/Acrylamide/Carboxylic Acids Polymers." Gels 7, no. 3 (2021): 113. http://dx.doi.org/10.3390/gels7030113.

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Smart hydrogels (SH) were prepared by thermal free radical polymerization of N-isopropyl acrylamide (NIPAAm), acrylamide (AAm) with acrylic acid (A) or maleic acid (M), and N,N′-methylene bisacrylamide. Spectroscopic and thermal characterizations of SHs were performed using FTIR, TGA, and DSC. To determine the effects of SHs on swelling characteristics, swelling studies were performed in different solvents, solutions, temperatures, pHs, and ionic strengths. In addition, cycle equilibrium swelling studies were carried out at different temperatures and pHs. The temperature and pH transition poin
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Shields, M., L. Tonmyr, and W. Hovdestad. "Is child sexual abuse declining in Canada? Results from nationally representative retrospective surveys." Health Promotion and Chronic Disease Prevention in Canada 36, no. 11 (2016): 252–60. http://dx.doi.org/10.24095/hpcdp.36.11.03.

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Introduction Numerous data sources suggest a decline in child sexual abuse (CSA) in the United States since the early 1990s. Some evidence also indicates that an earlier period of higher CSA incidence began following World War II. This study examines prevalence estimates of sexual abuse reported retrospectively as having occurred in childhood (ChSA) in two nationally representative surveys of the Canadian population. Methods Data are from 13 931 respondents aged 18 to 76 years from the 2004/2005 Canadian Gender, Alcohol, and Culture: An International Study (GENACIS), and from 22 169 household
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Rogg, Luise E., Jarrod R. Fortwendel, Praveen Rao Juvvadi, Amanda Lilley, and William J. Steinbach. "The chitin synthase genes chsA and chsC are not required for cell wall stress responses in the human pathogen Aspergillus fumigatus." Biochemical and Biophysical Research Communications 411, no. 3 (2011): 549–54. http://dx.doi.org/10.1016/j.bbrc.2011.06.180.

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Weiss, Nava, Abraham Sztejnberg, and Oded Yarden. "The chsA gene, encoding a class-I chitin synthase from Ampelomyces quisqualis." Gene 168, no. 1 (1996): 99–102. http://dx.doi.org/10.1016/0378-1119(95)00722-9.

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Shaw, J. A., P. C. Mol, B. Bowers, et al. "The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle." Journal of Cell Biology 114, no. 1 (1991): 111–23. http://dx.doi.org/10.1083/jcb.114.1.111.

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The morphology of three Saccharomyces cerevisiae strains, all lacking chitin synthase 1 (Chs1) and two of them deficient in either Chs3 (calR1 mutation) or Chs2 was observed by light and electron microscopy. Cells deficient in Chs2 showed clumpy growth and aberrant shape and size. Their septa were very thick; the primary septum was absent. Staining with WGA-gold complexes revealed a diffuse distribution of chitin in the septum, whereas chitin was normally located at the neck between mother cell and bud and in the wall of mother cells. Strains deficient in Chs3 exhibited minor abnormalities in
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Rodrigues, Lucas, Thaynan Vieira, Garrett Harvey, et al. "Abstract 55: High frequency of TP53 mutations in canine skin tumors recapitulates solar induced human lesions representing an important research model of spontaneous diseases." Cancer Research 83, no. 7_Supplement (2023): 55. http://dx.doi.org/10.1158/1538-7445.am2023-55.

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Abstract Skin tumors are the most common type of neoplastic lesion affecting humans and dogs, and their incidence is increasing for both species. Skin tumor initiation and progression are associated with chronic exposure to ultraviolet (UV) radiation, mainly for light-skinned individuals, that can activate different oncogenes and pathways. Solar UV-induced mutations, characterized by C to T or CC to TT mutations, are well described in the TP53 gene in human skin cancers such as ​​basal cell carcinoma, squamous cell carcinoma and melanoma. This study evaluated TP53 mutations in 2201 canine tumo
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Carreño-López, Ricardo, Araceli Sánchez, Nohemí Camargo, Claudine Elmerich, and Beatriz Eugenia Baca. "Characterization of chsA, a new gene controlling the chemotactic response in Azospirillum brasilense Sp7." Archives of Microbiology 191, no. 6 (2009): 501–7. http://dx.doi.org/10.1007/s00203-009-0475-x.

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Fujiwara, M., M. Ichinomiya, T. Motoyama, H. Horiuchi, A. Ohta, and M. Takagi. "Evidence That the Aspergillus nidulans Class I and Class II Chitin Synthase Genes, chsC and chsA, Share Critical Roles in Hyphal Wall Integrity and Conidiophore Development." Journal of Biochemistry 127, no. 3 (2000): 359–66. http://dx.doi.org/10.1093/oxfordjournals.jbchem.a022616.

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Ichinomiya, Masayuki, Akinori Ohta, and Hiroyuki Horiuchi. "Expression of asexual developmental regulator gene abaA is affected in the double mutants of classes I and II chitin synthase genes, chsC and chsA, of Aspergillus nidulans." Current Genetics 48, no. 3 (2005): 171–83. http://dx.doi.org/10.1007/s00294-005-0004-7.

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Blouin, M., M. Sirois, M. Aubertin-Leheudre, et al. "P054: Do biomarkers need clinical attention among pre-frail injured seniors seen in the ED." CJEM 19, S1 (2017): S96. http://dx.doi.org/10.1017/cem.2017.256.

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Introduction: Frailty is associated with functional decline and physiological impairments in seniors with minor injuries. Serum biomarkers have also been suggested as potential markers of these impairments in clinical studies. However, no study has addressed the usefulness of serum biomarkers among pre-frail seniors consulting emergency departments (ED) in order to detect these impairments.Objectives: The purpose of the present study was to explore the association between several serum biomarkers and the frailty status of seniors seen in ED for a minor injury who are at risk of functional decl
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Amraja, Essam, Raja Buras Ali, Abdulnaser Elsherif, Maryam SE Hussein, and Hwuida Kattab. "THE DIFFERENCE BETWEEN THE REPORTS FROM ASTHMATIC CHILDREN AND THEIR PARENTS ABOUT THE EFFECT OF ASTHMA ON THEIR QUALITY OF LIFE IN PEDIATRIC HOSPITAL-BENGHAZI-LIBYA." International Journal of Advanced Research 9, no. 06 (2021): 01–08. http://dx.doi.org/10.21474/ijar01/12982.

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Introduction: Childhood asthma is a serious health problem that results in impairment of physical and social life of the affected children. Objective: The current study identifies the effect of asthma on asthmatic children quality of life and also to assess the differences between childs and parents report about the effect of the asthma on the childs physical health, childs emotional health and childs activity. Method: A cross-sectional, descriptive, quantitative study was carried out where about Sixty-four participants of asthmatic children with their parents that were attached at Pediatric H
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XIANG, Tai-He, Ji-Ming XU, Lin WANG, and Lei LIN. "Cloning and Analysis of Two Promoters of Chalcone Synthase Gene A (chsA) in Petunia hybrida*." PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 38, no. 1 (2011): 75–83. http://dx.doi.org/10.3724/sp.j.1206.2010.00407.

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Müller, Christian, Carsten M. Hjort, Kim Hansen, and Jens Nielsen. "Altering the expression of two chitin synthase genes differentially affects the growth and morphology of Aspergillus oryzae The GenBank accession numbers for the chsB, chsC and chsA gene sequences reported in this paper are AY029261, AF410464 and AF429307, respectively." Microbiology 148, no. 12 (2002): 4025–33. http://dx.doi.org/10.1099/00221287-148-12-4025.

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Tuli, Krishan, and Manisha Malhotra. "A Hybrid Approach for Task Scheduling in the Cloud Environment." International Journal of Cloud Applications and Computing 12, no. 1 (2022): 1–14. http://dx.doi.org/10.4018/ijcac.305215.

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In today’s world, Cloud Computing has been considered as the best concept for the virtualization of various resources. There are various approaches that have been available for improvising the load balancing and also to improvise the job scheduling in the concept of cloud. Cloud Computing has offers the on-demand allocation of resources to users and this feature of cloud makes it a best among various technologies. Cloud computing provides great performance in less maintenance cost. So, Task scheduling has become a very important factor in enhancing the performance of resources dynamically and
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Cai, Yuhao, Huilin Chen, Mengfan Hu, Xuegui Wang, and Lei Zhang. "Discovery of Novel Potential Insecticide-Resistance Mutations in Spodoptera frugiperda." Insects 15, no. 3 (2024): 186. http://dx.doi.org/10.3390/insects15030186.

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The fall armyworm (FAW), Spodoptera frugiperda, is a worldwide agricultural pest that invaded China in 2018, and has developed resistance to multiple insecticides. The evolution of insecticide resistance is facilitated by mutations of target genes responsible for conferring resistance. In this study, amplicon sequencing analyzed 21 sites in six resistance genes. In addition to known mutations, unknown variants were also found, including novel variants: F290C (ace-1 gene, 0.1% frequency), I1040T/V (CHSA gene, 0.1% frequency), A309T (GluCl gene, 0.1% frequency), and I4790T/V (RyR gene, 0.1% freq
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Emond, M., M. Blouin, M. Sirois, et al. "LO14: In emergency department, do serum biomarkers are useful to screen independent frail seniors exposed to functional or mobility impairments after a minor injury?" CJEM 20, S1 (2018): S11. http://dx.doi.org/10.1017/cem.2018.76.

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Introduction: Frailty is a geriatric syndrome conferring a high risk of declining functional capacities. Some serum biomarkers were associated with frailty, but no study has investigated this possible association among community-dwelling seniors with minor injuries in the emergency department (ED). The aim was to determine if ED serum biomarker assay combined with frailty status improve the prediction of 3-months functional or mobility impairments in this population, beyond frailty status alone. Methods: This prospective sub-study of the CETI cohort includes 190 participants (age 65 years, ED
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Gow, N. A. R., B. Hube, D. A. Bailey, et al. "Genes associated with dimorphism and virulence of Candida albicans." Canadian Journal of Botany 73, S1 (1995): 335–42. http://dx.doi.org/10.1139/b95-264.

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Strategies for the analysis of a range of Candida albicans genes, whose expression is regulated during the yeast to hyphal transition (dimorphism), including genes encoding putative virulence factors, are reviewed. To help discriminate among genes whose products were the cause or consequence of dimorphism, temporal changes in the levels of the mRNAs of these and other genes were examined by northern analysis. The mRNA levels of most genes that were examined increased or decreased, transiently or persistently indicating complex alterations in gene expression during morphogenesis. Genes encoding
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J., T. Palacio-Haro, Zurita-Ángles M., Juárez-Palacios I.E., Flores Dorantes M.T., and González Díaz A. "Recuperación de suelo contaminado con petróleo mediante microorganismos petrofílicos y un mejorador de permeabilidad." Coloquio de Investigación Multidisciplinaria 7, no. 1 (2019): 1504–10. https://doi.org/10.5281/zenodo.4278283.

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La explotación, producción, refinación, transporte de petróleo y sus derivados conlleva ocasionalmente accidentes técnicos y operacionales que causan severo deterioro al ambiente y daños irreversibles a los ecosistemas. En la actualidad, Tabasco, México se encuentra bajo un marcado proceso de degradación de sus recursos naturales, particularmente de sus suelos, en particular los Gleysoles, grupo dominante. Por lo que el desarrollo de técnicas de remediación para estos suelos es apremiante. En esta investigación se eva
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Saxena, Shipra, K. R. K. Reddy, and M. V. Rajam. "dsRNA-mediated silencing of chitin synthase A (CHSA) affects growth and development of Leucinodes orbonalis, brinjal fruitand shoot borer." Journal of Asia-Pacific Entomology 25, no. 2 (2022): 101908. http://dx.doi.org/10.1016/j.aspen.2022.101908.

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van der Meer, Ingrid M., Cornelis E. Spelt, Joseph N. M. Mol, and Antoine R. Stuitje. "Promoter analysis of the chalcone synthase (chsA) gene of Petunia hybrida: a 67 bp promoter region directs flower-specific expression." Plant Molecular Biology 15, no. 1 (1990): 95–109. http://dx.doi.org/10.1007/bf00017727.

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