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Santi, P., K. A. Joiner, C. H. Hammer, M. M. Frank, and R. Tosi. "A complement-resistant HeLa cell line (T638) is blocked at the step of C3 deposition." Journal of Immunology 138, no. 10 (1987): 3385–91. http://dx.doi.org/10.4049/jimmunol.138.10.3385.

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Abstract A complement-resistant line of HeLa cells (T638) was derived by serial passage of complement-susceptible HeLa cells in anti-beta 2-microglobulin (b2m) antiserum and complement. The T638 line maintained stable complement resistance when passed for an additional 1500 generations in the absence of antiserum and complement. T638 cells expressed equivalent levels of cell-associated b2m as did the parent HeLa cell line. Furthermore, T638 cells were resistant to killing by complement and anti-HeLa antiserum with specificity for molecules other than b2m. These results indicate that the resist
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Lee, Meng-Tse, Bo-Yu Chen, and Wen-Chi Lu. "Failure-Robot Path Complementation for Robot Swarm Mission Planning." Applied Sciences 9, no. 18 (2019): 3756. http://dx.doi.org/10.3390/app9183756.

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Currently, unmanned vehicles are widely used in different fields of exploration. Due to limited capacities, such as limited power supply, it is almost impossible for one unmanned vehicle to visit multiple wide areas. Multiple unmanned vehicles with well-planned routes are required to minimize an unnecessary consumption of time, distance, and energy waste. The aim of the present study was to develop a multiple-vehicle system that can automatically compile a set of optimum vehicle paths, complement failed assignments, and avoid passing through no-travel zones. A heuristic algorithm was used to o
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Leeth, Caroline McPhee, Jing Zhu, Ashley Potter, Muneer Hasham, Madison Richwine, and Derry C. Roopenian. "AID deficiency greatly improves survival and diminishes renal pathology in the BXSB mouse model of SLE." Journal of Immunology 202, no. 1_Supplement (2019): 116.12. http://dx.doi.org/10.4049/jimmunol.202.supp.116.12.

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Abstract Eight years have passed since the approval of belimumab, a monoclonal antibody directed against B lymphocyte stimulation and the first targeted therapy approved for systemic lupus. erythematous (SLE). While well tolerated, the efficacy of belimumab remains limited and is not recommended for patients suffering severe nephritis, a life threatening complication of SLE. We sought to explore alternative targets of autoreactive B lymphocytes through manipulation of affinity maturation. The BXSB model is a long established model of human SLE developing elevated antinuclear antibodies and imm
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Sanjay, Srinivasan, Isha Acharya, Priya Srinivasan, and Padmamalini Mahendradas. "Multimodal imaging in radiation retinopathy following orbital metastasis." Medical hypothesis, discovery & innovation in optometry 4, no. 3 (2023): 141–47. http://dx.doi.org/10.51329/mehdioptometry184.

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Background: Radiation retinopathy is a major cause of vision loss in patients receiving radiotherapy to the head and orbit. Diabetic retinopathy is included in the differential diagnosis owing to similar clinical features, including microaneurysms, cotton-wool spots, hard exudates, and macular edema. The only significant pathological difference is that radiation retinopathy spares pericytes, unlike diabetic retinopathy. Multimodal imaging helps diagnose and predict the prognosis of radiation retinopathy, which is presented in this case report.
 Case Presentation: A 55-year-old woman diagn
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Ueda, Yasutaka, Makiko Osato, Wynne Weston-Davies, et al. "Coversin Blocked in Vitro Hemolysis in an Eculizumab-Resistant PNH Patient with the C5 Polymorphism (c.2654G>A)." Blood 126, no. 23 (2015): 2138. http://dx.doi.org/10.1182/blood.v126.23.2138.2138.

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Abstract Background: Paroxysmal Nocturnal Hemoglobinurea (PNH) is a rare stem cell disease caused by the expansion of PIGA mutated clone(s). PNH-type cells are deficient in the expression of GPI-anchored proteins including DAF and CD59, which protect red blood cells (RBC) from complement-mediated intravascular hemolysis. Eculizumab (Soliris®, Alexion Pharmaceuticals) is a humanized monoclonal antibody against C5 which efficiently inhibits hemolysis by blocking the terminal complement cascade. Eculizumab dramatically ameliorates several clinical symptoms, and improves the prognosis in PNH patie
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BORSLEY, ROBERT D. "On so-called transitive expletives in Belfast English." English Language and Linguistics 13, no. 3 (2009): 409–31. http://dx.doi.org/10.1017/s1360674309990177.

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Henry & Cottell (2007) argue that Belfast English (BE) sentences such asThere shouldn't anybody say thatandThere've lots of people passed the testare transitive expletive constructions (TECs) similar to those that are a feature of Icelandic. They propose that the difference between BE and Standard English (SE) is that whereas expletivethereis introduced in Spec vP in the latter it is introduced in Spec TP in the former. On the assumption that transitive subjects originate in Spec vP, this entails that expletivetherecannot co-occur with a transitive verb. While it is clear that BE is differ
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FARIAS, Ediênio Vieira, and Maria de Lourdes Soares ORNELLAS. "(A)muros Atravessados na Educação: Representações Insurgentes Frente às Consequências da Modernidade." INTERRITÓRIOS 7, no. 13 (2021): 146. http://dx.doi.org/10.51359/2525-7668.2021.250047.

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Este escrito apresenta os atravessamentos dos (a)muros na educação contemporânea enquanto representações insurgentes às consequências da modernidade. Esta temática emerge ante a construção do objeto de pesquisa, em fase de doutoramento, no cenário educativo do Programa Pós-graduação em Educação e Contemporaneidade da Universidade do Estado da Bahia. A tese doutoral se institui em torno da constituição do professor-sujeito frente aos (a)muros da educação contemporânea. Estes (a)muros, expressão lacaniana, rementem ao ato de castração do sujeito (ou de negação desse processo), ao tempo, que mani
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Khayame, Houda A., and Mona M. Abdeljawad. "Systems Thinking in Upstream Social Marketing: Using Soft Systems Methodology to Improve Midwifery Policy in Jordan." Social Marketing Quarterly 26, no. 2 (2020): 167–83. http://dx.doi.org/10.1177/1524500420925810.

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Background: Despite being acknowledged worldwide as essential maternal care providers, midwives remain marginalized in the Jordanian healthcare system. Further, considering Jordan’s goal to achieve a total fertility rate of 2.1 by 2030 and Jordanian women’s preference for female providers, enhancing midwives’ role could significantly promote the use of reproductive health and family planning services. Focus of the Article: We report on opportunities created by opening the boundary of our social marketing understanding to systems thinking in practice (STiP), using soft systems methodology (SSM)
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Morrison, Umor Iwele. "The workplace and evolving ethics for worthwhile productivity in the education sector." GPH-International Journal of Educational Research 8, no. 01 (2025): 302–13. https://doi.org/10.5281/zenodo.14674704.

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Abstract This paper focused on the workplace and evolving ethics for worthwhile productivity with a focus on education. This becomes necessary because the education sector is bedevilled with several breaches ranging from insubordination, neglect of duty, physical confrontation, litigation, contempt of duty, examination fraud, misappropriation of funds, witch-hunting, the illegality of different magnitude and other forms of breaches. The paper explained basic concepts such as ethics, workplace ethics, leadership ethics, employees’ ethics, and morality. The project is that ethics are unive
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Santosa, I. Gusti Ngurah Putra Eka, and I. Gusti Agung Ayu Istri Adnyeswari. "Integration of Ethnomedicine in Basic Medicine: A Literature Review and Its Potential for Medical Practice." International Journal Of Scientific Advances 5, no. 4 (2024). http://dx.doi.org/10.51542/ijscia.v5i4.13.

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Background: The integration of ethnomedicine into primary medicine has become an increasingly relevant topic in recent decades. Ethnomedicine, which refers to traditional healing practices passed down through generations and used by various cultures worldwide, offers significant potential to complement modern medical practices. Objective: This literature review aims to explore the potential created by the integration of ethnomedicine into primary medicine. Methods: This review utilizes a literature review method across multiple databases such as PubMed, Google Scholar, and SCISPACE. Results: E
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Wang, Chloe, Jackie Campbell, Harriet Lea-Banks, and Erika Lee. "Perflutren lipid microspheres for echocardiogram contrast: a clinical case of anaphylaxis not caused by PEG." Allergy, Asthma & Clinical Immunology 21, no. 1 (2025). https://doi.org/10.1186/s13223-025-00964-5.

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Abstract Background Perflutren lipid microsphere suspension, sold under the brand name Definity®, is a microbubble ultrasound contrast agent. The microspheres contain octafluoropropane (C3F8) gas encapsulated by an outer lipid shell of phospholipids and a polyethylene glycol (PEG)ylated phospholipid. Anaphylaxis to perflutren lipid microsphere is very rare, with only one case report clearly attributing the reaction to the PEG excipient. We report a novel case of anaphylaxis likely caused by a non-PEGylated component of Definity®. Case presentation Our patient is a healthy 54-year-old female, w
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LABZAE, Oumaima, and Samir BEL-AMIN. "La loi 15.18 relative crowdfunding marocain : une réponse législative à la diversification des sources de financement." International Journal Of Applied Management And Economics Vol 02, N°14 (2025). https://doi.org/10.5281/zenodo.15586344.

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<strong>R&eacute;sum&eacute; :</strong> Le d&eacute;veloppement d&rsquo;Internet et l&rsquo;essor des outils de communication num&eacute;riques ont favoris&eacute; l&rsquo;&eacute;mergence de nouveaux modes de financement, dont le succ&egrave;s ne cesse de se confirmer. Longtemps consid&eacute;r&eacute; avec scepticisme par certains, qui le pr&eacute;disaient vou&eacute; &agrave; l&rsquo;&eacute;chec d&egrave;s ses d&eacute;buts, le crowdfunding &ndash; ou financement par la foule &ndash; a su r&eacute;sister aux al&eacute;as du monde des affaires et s&rsquo;imposer comme un m&eacute;canisme d
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Luger, Jason David. "Must Art Have a ‘Place’? Questioning the Power of the Digital Art-Scape." M/C Journal 19, no. 3 (2016). http://dx.doi.org/10.5204/mcj.1094.

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Introduction Artist: June 2 at 11.26pm:‘To be truly radical is to make hope possible rather than despair convincing.’ - Raymond Williams. (Singaporean Artists’ public Facebook Post) Can the critical arts exist without ‘place’?There is an ongoing debate on ‘place’ and where it begins and ends; on the ways that cities exist in both material and immaterial forms, and thereby, how to locate and understand place as an anchoring point amidst global flows (Massey; Merrifield). This debate extends to the global art- scape, as traditional conceptions of art and art-making attached to place require re-t
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Robards, Brady. "Digital Traces of the Persona through Ten Years of Facebook." M/C Journal 17, no. 3 (2014). http://dx.doi.org/10.5204/mcj.818.

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When I think, rarely, about the articulation of the set of traces that I am leaving, I have the immediate apprehension that it is not the real me that’s out there on the Web. I know the times when I have censored myself (oh problematic concept!) and when I have performed actions to complement—and frequently to confound—a trace. […] Taken globally, the set of traces that we leave in the world does without doubt add up to something. It is through operations on sets of traces that I understand an event that I take part in. (Bowker 23) Over the past decade, Facebook has become integrated into the
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Lymn, Jessie. "Migration Histories, National Memory, and Regional Collections." M/C Journal 22, no. 3 (2019). http://dx.doi.org/10.5204/mcj.1531.

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IntroductionThis article suggests extensions to the place of ‘national collections’ of Australia’s migration histories, and considers the role of regional libraries and museums in collecting, preserving, and making accessible the history of migration. The article describes a recent collaboration between the Bonegilla Migrant Experience site, the Albury LibraryMuseum and the regionally-based Charles Sturt University (CSU) to develop a virtual, three-dimensional tour of Bonegilla, a former migrant arrival centre. Through this, the role of regional collections as keeping places of migration memor
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