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1

Yin, Changxi, Yanchun Zhu, Xuefei Li, and Yongjun Lin. "Molecular and Genetic Aspects of Grain Number Determination in Rice (Oryza sativa L.)." International Journal of Molecular Sciences 22, no. 2 (January 13, 2021): 728. http://dx.doi.org/10.3390/ijms22020728.

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Rice grain yield is a complex trait determined by three components: panicle number, grain number per panicle (GNPP) and grain weight. GNPP is the major contributor to grain yield and is crucial for its improvement. GNPP is determined by a series of physiological and biochemical steps, including inflorescence development, formation of rachis branches such as primary rachis branches and secondary rachis branches, and spikelet specialisation (lateral and terminal spikelets). The molecular genetic basis of GNPP determination is complex, and it is regulated by numerous interlinked genes. In this re
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Ma, Biao, Shangqi Nie, Minghui Ji, Jeho Song, and Wei Wang. "Research and Analysis of Sports Training Real-Time Monitoring System Based on Mobile Artificial Intelligence Terminal." Wireless Communications and Mobile Computing 2020 (September 24, 2020): 1–10. http://dx.doi.org/10.1155/2020/8879616.

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With the rapid development of artificial intelligence, related technologies and applications come into being, and industries based on artificial intelligence are booming, among which image recognition and target tracking technologies are widely used in various fields, especially in the fields of security monitoring and augmented reality. In this paper, combined with the characteristics of athletes, based on mobile artificial intelligence terminal technology, the C/S mode of athlete training process monitoring system is developed and designed, which uses GPS to obtain the real-time position inf
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Ishitsuka, Yosuke, and Dennis R. Roop. "Loricrin: Past, Present, and Future." International Journal of Molecular Sciences 21, no. 7 (March 25, 2020): 2271. http://dx.doi.org/10.3390/ijms21072271.

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The terminal differentiation of the epidermis is a complex physiological process. During the past few decades, medical genetics has shown that defects in the stratum corneum (SC) permeability barrier cause a myriad of pathological conditions, ranging from common dry skin to lethal ichthyoses. Contrarily, molecular phylogenetics has revealed that amniotes have acquired a specialized form of cytoprotection cornification that provides mechanical resilience to the SC. This superior biochemical property, along with desiccation tolerance, is attributable to the proper formation of the macromolecular
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Epple, Bernhard, and Hennes Henniger. "Discussion on design aspects for free-space optical communication terminals." IEEE Communications Magazine 45, no. 10 (October 2007): 62–69. http://dx.doi.org/10.1109/mcom.2007.4342824.

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Andersson, G. B. J. "Biomechanical aspects of sitting: An application to VDT terminals." Behaviour & Information Technology 6, no. 3 (July 1987): 257–69. http://dx.doi.org/10.1080/01449298708901833.

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Bittante, Alice, and Henrik Saxén. "Design of Small LNG Supply Chain by Multi-Period Optimization." Energies 13, no. 24 (December 18, 2020): 6704. http://dx.doi.org/10.3390/en13246704.

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A mathematical model for the design of small-scale supply chains for liquefied natural gas (LNG) has been developed. It considers the maritime delivery of LNG from supply ports to satellite terminals and land-based transports from the terminals to consumers on or off the coast. Both tactical and strategic aspects in the supply chain design are addressed by optimizing the maritime routing of a heterogeneous fleet of ships, truck connections, and the locations of the satellite terminals. The objective is to minimize the overall cost, including operation and investment costs for the selected time
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Nowak, Gabriel, Marta Kubera, and Michael Maes. "Neuroimmunological aspects of the alterations in zinc homeostasis in the pathophysiology and treatment of depression." Acta Neuropsychiatrica 12, no. 2 (June 2000): 49–53. http://dx.doi.org/10.1017/s0924270800035705.

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SUMMARYZinc is a trace element which plays a fundamental role in a wide range of biochemical processes in living organisms. Zinc is an essential component of various proteins and is an important factor for physiological function of the mammalian nervous and immune systems. In the central nervous system (CNS), zinc is found at high concentrations in hippocampal neurons. These neurons possess mechanisms for zinc uptake and storage in synaptic terminals and for the stimulation of zinc release along with neurotransmitters. In the central nervous system, zinc modulates predominantly the excitatory
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Bessler, Sandford. "A System for Locating Mobile Terminals with Tunable Privacy." Journal of Theoretical and Applied Electronic Commerce Research 2, no. 2 (August 1, 2007): 82–91. http://dx.doi.org/10.3390/jtaer2020016.

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A number of approaches for capturing and processing location information of mobile users have been proposed in the past; however, only with the latest advances in the handset technology, a terminal-based positioning approach, using overlay SIP signaling on top of a packet switched bearer and area notification as basic functionality becomes feasible for mass applications. Especially in electronic commerce scenarios, in which users often interact with non-trusted services and shops, any location-based solution has to consider privacy aspects as well. The terminal-centric model presented in the p
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Comitato, Antonella, and Rita Bardoni. "Presynaptic Inhibition of Pain and Touch in the Spinal Cord: From Receptors to Circuits." International Journal of Molecular Sciences 22, no. 1 (January 2, 2021): 414. http://dx.doi.org/10.3390/ijms22010414.

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Sensory primary afferent fibers, conveying touch, pain, itch, and proprioception, synapse onto spinal cord dorsal horn neurons. Primary afferent central terminals express a wide variety of receptors that modulate glutamate and peptide release. Regulation of the amount and timing of neurotransmitter release critically affects the integration of postsynaptic responses and the coding of sensory information. The role of GABA (γ-aminobutyric acid) receptors expressed on afferent central terminals is particularly important in sensory processing, both in physiological conditions and in sensitized sta
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10

Nikolaeva, Shantimora Gala, and Dan Nathan-Roberts. "Various Aspects of the Human Factor in Online Education." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 60, no. 1 (September 2016): 1279–83. http://dx.doi.org/10.1177/1541931213601297.

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The goal of this proceeding is to summarize the current research trends in human factors of studying Massive Open Online Courses (MOOCs), and to quantify the frequency of literature publications each of these trends. This proceeding performs quantitative analysis of 154 sources, grouped by key aspects of research: psychological, technological, and physiological, and by the main object/subject of study: learner, instructor, or teaching methodologies. Based on the results of this analysis, two suggestions can be made: a.) further research of effective human-computer interactions in online educat
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11

Chang and Zhu. "A Novel Two-Stage Heuristic for Solving Storage Space Allocation Problems in Rail–Water Intermodal Container Terminals." Symmetry 11, no. 10 (October 2, 2019): 1229. http://dx.doi.org/10.3390/sym11101229.

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In the past, most researchers have paid attention to the storage space allocation problem in maritime container terminals, while few have studied this problem in rail–water intermodal container terminals. Therefore, this paper proposes a storage space allocation problem to look for a symmetry point between the efficiency and effectivity of rail–water intermodal container terminals and the unbalanced allocations and reallocation operations of inbound containers in the railway operation area, which are two interactive aspects. In this paper, a two-stage model on the storage space allocation prob
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Wang, Haiwei, Jianrong Liu, and Feng You. "Physiological Characteristics and Nonparametric Test for Master-Slave Driving Task’s Mental Workload Evaluation in Mountain Area Highway at Night." Journal of Advanced Transportation 2019 (December 3, 2019): 1–11. http://dx.doi.org/10.1155/2019/2061532.

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With the rapid development of advanced mobile intelligent terminals, driving tasks are diverse, and new traffic safety problems occur. We propose a new research on physiological characteristics and nonparametric tests for the master-slave driving task, especially for evaluation of drivers’ mental workload in mountain area highway in nighttime scenario. First, we establish the experimental platform based driving simulator and design the master-slave driving task. Second, based on the physiological data and subjective evaluation for mental workload, we use statistical methods to composite the ph
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Granger, P., and H. Depoortere. "Aspects of Sleep-Wakefulness Architecture by Computer Analysis in Cats." Neuropsychobiology 19, no. 4 (1988): 212–16. http://dx.doi.org/10.1159/000118462.

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Wang, Qingyu. "Tennis Online Teaching Information Platform Based on Android Mobile Intelligent Terminal." Mobile Information Systems 2021 (June 29, 2021): 1–11. http://dx.doi.org/10.1155/2021/2932441.

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With the development of the information age, there is almost one mobile smart device based on android, which is inseparable from mobile smart devices in both learning and life. In order to explore the effects of mobile smart devices on tennis teaching, this article mainly introduces the research on the tennis online teaching information platform based on android mobile smart terminals. This article first uses the android system framework and software architecture to design the technical aspects of the tennis online teaching information platform and then analyzes and improves the functional and
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15

Babiker, Areej, Yahia Baashar, Ammar Ahmed Alkahtani, Ibrahima Faye, and Gamal Alkawsi. "Towards Detection of Interest Using Physiological Sensors." Applied Sciences 11, no. 3 (February 1, 2021): 1318. http://dx.doi.org/10.3390/app11031318.

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The positive effects of interest on different aspects, e.g., learning and education, economy, psychological well-being, and social relations, have been widely addressed by many psychological and physiological studies in the last two decades. While the psychological work has investigated this impact of interest theoretically, the physiological studies have focused more on the modulatory effects. However, some studies have addressed both sides of the effects. In this work, we conduct a comprehensive review of physiological studies on interest detection, from different perspectives carried out be
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Kurzanov, A. N., and I. M. Bykov. "NEUROMODULATOR LIGAND-RECEPTOR SYSTEM TIP39 - PTH2R." Crimea Journal of Experimental and Clinical Medicine 10, no. 2 (2020): 78–85. http://dx.doi.org/10.37279/2224-6444-2020-10-2-78-85.

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Widely spread axon terminals of TIP39 neurons have a distribution similar to PTH2R containing neurons and their fibers which provides an anatomic base of neuromodulation action of TIP39. This functional and anatomic link- ing lets state that TIP39 and PTH2R form a neuromodulator ligand-receptor system. Basing on mechanisms of signal transmission used by TIP39 and PTH2R, they can form a neuromodulator system in many brain parts. TIP39-PTH2R system is a unique neuropeptide-receptor system, which localization and functions in the central nervous system differ from any other neuropeptides. Neuromo
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Ciruela, Francisco. "Special Issue: G Protein-Coupled Adenosine Receptors: Molecular Aspects and Beyond." International Journal of Molecular Sciences 21, no. 6 (March 15, 2020): 1997. http://dx.doi.org/10.3390/ijms21061997.

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Adenosine is a purine nucleoside present in all human cells where it plays many different physiological roles: From being a building block for nucleic acids to a key constituent of the biological energy currency ATP [...]
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18

Li, Xiaohe, Xingming Zhang, and Haoxiang Wang. "A Research on Fast Face Feature Points Detection on Smart Mobile Devices." Wireless Communications and Mobile Computing 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/9729014.

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We explore how to leverage the performance of face feature points detection on mobile terminals from 3 aspects. First, we optimize the models used in SDM algorithms via PCA and Spectrum Clustering. Second, we propose an evaluation criterion using Linear Discriminative Analysis to choose the best local feature descriptions which plays a critical role in feature points detection. Third, we take advantage of multicore architecture of mobile terminal and parallelize the optimized SDM algorithm to improve the efficiency further. The experiment observations show that our final accomplished GPC-SDM (
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19

Lv, Kaiyue, Zhong Sun, and Min Xu. "Artificial Intelligent Based Video Analysis on the Teaching Interaction Patterns in Classroom Environment." International Journal of Information and Education Technology 11, no. 3 (2021): 126–30. http://dx.doi.org/10.18178/ijiet.2021.11.3.1500.

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Recently, the development of technology has enriched the form of classroom interaction. Exploring the characteristics of current classroom teaching interaction forms can clarify the deficiencies of teaching interactions, thereby improving teaching. Based on the existing classroom teaching interactive coding system, this paper adopted ITIAS coding system, and took classroom with interactive whiteboard, interactive television or mobile terminals as research scene, selected 20 classroom videos of teaching cases in this environment as research objects. Computer vision, one of the artificial intell
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20

Lin, Jen-Wei, Qinghao Fu, and Tariq Allana. "Probing the Endogenous Ca2+ Buffers at the Presynaptic Terminals of the Crayfish Neuromuscular Junction." Journal of Neurophysiology 94, no. 1 (July 2005): 377–86. http://dx.doi.org/10.1152/jn.00617.2004.

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Ca2+ indicators of varying affinity and mobility were pressure injected into the presynaptic axon of the inhibitor of the crayfish neuromuscular junction (NMJ). Fluorescence transients recorded at a 2-kHz resolution were used to probe physiological parameters governing the decay of fluorescence transients within 100 ms after an action potential (early decay). Blocking Ca2+ extrusion or Ca2+ sequestration processes did not significantly alter early decay, arguing against a role for either mechanism. Fluorescence transients recorded with low mobility or fixed indicators exhibited early decay sim
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Amadeo, Alida, Sara Pizzi, Alessandro Comincini, Debora Modena, Alessandra Maria Calogero, Laura Madaschi, Gaia Faustini та ін. "The Association between α-Synuclein and α-Tubulin in Brain Synapses". International Journal of Molecular Sciences 22, № 17 (25 серпня 2021): 9153. http://dx.doi.org/10.3390/ijms22179153.

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α-synuclein is a small protein that is mainly expressed in the synaptic terminals of nervous tissue. Although its implication in neurodegeneration is well established, the physiological role of α-synuclein remains elusive. Given its involvement in the modulation of synaptic transmission and the emerging role of microtubules at the synapse, the current study aimed at investigating whether α-synuclein becomes involved with this cytoskeletal component at the presynapse. We first analyzed the expression of α-synuclein and its colocalization with α-tubulin in murine brain. Differences were found be
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Bargaz, Adnane, Mainassara Zaman-Allah, Mohamed Farissi, Mohamed Lazali, Jean-Jacques Drevon, Rim Maougal, and Carlsson Georg. "Physiological and Molecular Aspects of Tolerance to Environmental Constraints in Grain and Forage Legumes." International Journal of Molecular Sciences 16, no. 8 (August 13, 2015): 18976–9008. http://dx.doi.org/10.3390/ijms160818976.

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Persiani, Sandra G. L., Bilge Kobas, Sebastian Clark Koth, and Thomas Auer. "Biometric Data as Real-Time Measure of Physiological Reactions to Environmental Stimuli in the Built Environment." Energies 14, no. 1 (January 4, 2021): 232. http://dx.doi.org/10.3390/en14010232.

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The physiological and cognitive effects of environmental stimuli from the built environment on humans have been studied for more than a century, over short time frames in terms of comfort, and over long-time frames in terms of health and wellbeing. The strong interdependence of objective and subjective factors in these fields of study has traditionally involved the necessity to rely on a number of qualitative sources of information, as self-report variables, which however, raise criticisms concerning their reliability and precision. Recent advancements in sensing technology and data processing
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Khoirunnisaa', Khoirunnisaa'. "Perilaku Individu dalam Lembaga Pendidikan Islam." An-Nuha : Jurnal Kajian Islam, Pendidikan, Budaya dan Sosial 8, no. 1 (July 7, 2021): 131–45. http://dx.doi.org/10.36835/annuha.v8i1.401.

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The study of aspects of human behavior in a particular group which includes aspects caused by the influence of organizations on humans as well as human influences on organizations including organizational behavior. There are two factors that influence individual behavior towards Islamic educational institutions, namely internal and external factors. Internal factors include heredity (heredity or innate). External factors include the environment, maturity or experience and education. While the individual behavior analysis variables include psychological, physiological and environmental variable
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Barfield, Woodrow, and Eric Danas. "Comments on the Use of Olfactory Displays for Virtual Environments." Presence: Teleoperators and Virtual Environments 5, no. 1 (January 1996): 109–21. http://dx.doi.org/10.1162/pres.1996.5.1.109.

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Currently, the hardware to produce virtual environments does not include olfactory displays, in spite of the fact that a wealth of sensory information is available from the olfactory sense. This paper reviews the physiological and psychological aspects of olfaction and discusses the use of olfactory displays for virtual environments. Further, it outlines the information that will be needed by the virtual environment research community to integrate olfactory stimuli into virtual environments.
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Weisberg, David E. "The Electronic Push." Mechanical Engineering 122, no. 04 (April 1, 2000): 53–59. http://dx.doi.org/10.1115/1.2000-apr-4.

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This article explains the concept and various aspects of mechanical design automation (MDA). The use of computers for mechanical design is often referred to as MDA. Serious commercialization of computer graphics for design and drafting began in 1969 with the founding of Computervision and Application. The commercial market picked up significantly in 1975, when new 19-inch storage tube display terminals became readily available from Tektronix. These units could be used with minicomputers without custom interfaces, and they could display substantially larger drawings than the older, 11-inch unit
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Clewell, Harvey J., and Melvin E. Andersen. "Risk Assessment Extrapolations and Physiological Modeling." Toxicology and Industrial Health 1, no. 4 (October 1985): 111–34. http://dx.doi.org/10.1177/074823378500100408.

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The process of assessing the risk associated with human exposure to environmental chemicals inevitably relies on a number of assumptions, estimates and rationalizations. One of the more challenging aspects of risk assessment involves the need to extrapolate beyond the range of conditions used in experimental animal studies to predict anticipated human risks. The most obvious extrapolation required is that from the tested animal species to humans; but others are also generally required, including extrapolating from high dose to low dose, from one route of exposure to another and from one exposu
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Carulli, Daniela, and Joost Verhaagen. "An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity." International Journal of Molecular Sciences 22, no. 5 (February 28, 2021): 2434. http://dx.doi.org/10.3390/ijms22052434.

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During restricted time windows of postnatal life, called critical periods, neural circuits are highly plastic and are shaped by environmental stimuli. In several mammalian brain areas, from the cerebral cortex to the hippocampus and amygdala, the closure of the critical period is dependent on the formation of perineuronal nets. Perineuronal nets are a condensed form of an extracellular matrix, which surrounds the soma and proximal dendrites of subsets of neurons, enwrapping synaptic terminals. Experimentally disrupting perineuronal nets in adult animals induces the reactivation of critical per
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Мезенцева, Larisa Mezentseva, Перцов, and S. Pertsov. "Stability of Physiological Functions and Methods of Its Estimation." Journal of New Medical Technologies 21, no. 1 (June 4, 2014): 12–17. http://dx.doi.org/10.12737/3301.

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Problem of physiological functions stability is the important part of the theoretical physiology. P.K.Anohin´s basic ideas - the theory of functional systems and systemic approach to study of physiological functions have begun the development of theoretical physiology and mathematical modeling in biomedicine. In this paper methodological aspects of using of various biomodels for an estimation of stability of physiological functions are considered. Experimental, genetic, mathematical and computer biomodels are described. Practical techniques of an estimation of stability are illustrate
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Ashifa, Dr K. M., and -. "Addictive Behaviour among Women Viewers of Indian Soap Opera." Webology 18, Special Issue 03 (April 29, 2021): 127–36. http://dx.doi.org/10.14704/web/v18si03/web18030.

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Media is an integral part of society and it plays vital role for inculcating information. In the course of accomplishing its duties and functions, media, especially television influence on society relatively depending on the audience it reaches. Soaps have a predominant female audience. Some soaps do include men viewers but some social researchers pointed, women are considering most peculiar viewers. They are emotionally attached and value particular soaps in their personal and domestic life. Today people are leading a fast life. People should have some kind of recreation in their get relation
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Ashrafuzzaman, Md. "Artificial Intelligence, Machine Learning and Deep Learning in Ion Channel Bioinformatics." Membranes 11, no. 9 (August 31, 2021): 672. http://dx.doi.org/10.3390/membranes11090672.

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Ion channels are linked to important cellular processes. For more than half a century, we have been learning various structural and functional aspects of ion channels using biological, physiological, biochemical, and biophysical principles and techniques. In recent days, bioinformaticians and biophysicists having the necessary expertise and interests in computer science techniques including versatile algorithms have started covering a multitude of physiological aspects including especially evolution, mutations, and genomics of functional channels and channel subunits. In these focused research
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Santiago-Moreno, Julian, and Elisabeth Blesbois. "Functional Aspects of Seminal Plasma in Bird Reproduction." International Journal of Molecular Sciences 21, no. 16 (August 7, 2020): 5664. http://dx.doi.org/10.3390/ijms21165664.

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This review provides an updated overview of the seminal plasma composition, and the role of metabolic and protein components on the sperm function of avian species. In addition, the implication of seminal plasma on assisted reproductive techniques of birds was discussed. The semen of birds usually has exceptionally high sperm concentration with relatively little seminal plasma, but this contributes to very fast changes in sperm metabolism and function. The biochemical characteristics and physiological roles of the various seminal plasma components in birds (carbohydrates, lipids, amino acids,
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Fieselmann, Andreas, Markus Kowarschik, Arundhuti Ganguly, Joachim Hornegger, and Rebecca Fahrig. "Deconvolution-Based CT and MR Brain Perfusion Measurement: Theoretical Model Revisited and Practical Implementation Details." International Journal of Biomedical Imaging 2011 (2011): 1–20. http://dx.doi.org/10.1155/2011/467563.

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Deconvolution-based analysis of CT and MR brain perfusion data is widely used in clinical practice and it is still a topic of ongoing research activities. In this paper, we present a comprehensive derivation and explanation of the underlying physiological model for intravascular tracer systems. We also discuss practical details that are needed to properly implement algorithms for perfusion analysis. Our description of the practical computer implementation is focused on the most frequently employed algebraic deconvolution methods based on the singular value decomposition. In particular, we furt
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Pohjanvirta, Raimo, and Matti Viluksela. "Novel Aspects of Toxicity Mechanisms of Dioxins and Related Compounds." International Journal of Molecular Sciences 21, no. 7 (March 28, 2020): 2342. http://dx.doi.org/10.3390/ijms21072342.

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Dioxins and related compounds are common environmental contaminants. Although their levels have gone down, they are still of concern, in particular regarding developmental toxicity. The adverse effects of these compounds are mediated by the aryl hydrocarbon receptor (AHR), whose canonical signaling pathway has been unveiled in fair detail. The alternative (non-genomic) pathways are much more obscure. AHR has also proven to be a master regulator of numerous physiological phenomena, which has led to the search of selective AHR modulators with low toxicity. Papers of this Special Issue address th
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Markush, J. Peter C., Gary J. Grimes, and Jonathan R. Merril. "Investigations toward Using VRML for Distributed Medical Collaboration." Presence: Teleoperators and Virtual Environments 9, no. 4 (August 2000): 383–93. http://dx.doi.org/10.1162/105474600566880.

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This report describes preliminary research and experiments towards the collaborative viewing and manipulation of three-dimensional computer models of human anatomy and physiology on low-end computers using limited bandwidth. A proposed system is described using a set of recommended requirements. Experiments that were conducted to explore the feasibility of some aspects of the proposed system are also described. The resulting experimental system was implemented on networked 100 MHz and 90 MHz Pentium-based computers enhanced with 3-D graphics accelerators. Geometry for the anatomy models were s
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Miller, Anne, Cathie Steele, and Carlos Scheinkestel. "Extending clinical information systems design in the ICU." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 51, no. 11 (October 2007): 697–701. http://dx.doi.org/10.1177/154193120705101120.

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Miller and Sanderson (2003b) presented promising results for a prototype clinical information design developed according to Ecological Interface Design principles, but the size of the prototype made it impractical for onscreen display. This paper replicates the previous study using an onscreen presentation of the original EID divided according to functional systems. As in the original study, nurses' ability to detect patient change events was enhanced using the onscreen EID. However, there are differences between doctors' performance using the original and using the onscreen EID. Unlike the or
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Fleshman, J. W., I. Segev, and R. B. Burke. "Electrotonic architecture of type-identified alpha-motoneurons in the cat spinal cord." Journal of Neurophysiology 60, no. 1 (July 1, 1988): 60–85. http://dx.doi.org/10.1152/jn.1988.60.1.60.

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1. Measurements of input resistance (RN), time constant (tau 0), and electrotonic length (Lpeel) were derived from intracellular voltage changes produced by injection of current pulses in six type-identified triceps surae alpha-motoneurons. The motoneurons were labeled with horseradish peroxidase and subsequently reconstructed and measured from serial sections. These quantitative morphological and physiological data were incorporated into detailed computer models of the motoneurons. 2. Steady-state and dynamic models were used to determine values for specific membrane resistivity (Rm) that mat
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Ranieri, Marianna. "Renal Ca2+ and Water Handling in Response to Calcium Sensing Receptor Signaling: Physiopathological Aspects and Role of CaSR-Regulated microRNAs." International Journal of Molecular Sciences 20, no. 21 (October 27, 2019): 5341. http://dx.doi.org/10.3390/ijms20215341.

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Calcium (Ca2+) is a universal and vital intracellular messenger involved in a diverse range of cellular and biological processes. Changes in the concentration of extracellular Ca2+ can disrupt the normal cellular activities and the physiological function of these systems. The calcium sensing receptor (CaSR) is a unique G protein-coupled receptor (GPCR) activated by extracellular Ca2+ and by other physiological cations, aminoacids, and polyamines. CaSR is the main controller of the extracellular Ca2+ homeostatic system by regulating parathyroid hormone (PTH) secretion and, in turn, Ca2+ absorpt
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UCHIDA, Kazuhiko, Takeshi FUJISAKI, Yuriko HACHIYA, Rie YOSHIKAWA, Susumu ODA, Koji MORI, and Harutoshi OGAI. "Fatigue Estimation of Visual Display Terminal (VDT) Workers by Physiological Data -Preliminary Study of a New Computer Program for VDT Work Analysis-." Journal of UOEH 26, no. 3 (2004): 315–25. http://dx.doi.org/10.7888/juoeh.26.315.

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Sharma, Shalu, Antara Sengupta, and Shantanu Chowdhury. "Emerging Molecular Connections between NM23 Proteins, Telomeres and Telomere-Associated Factors: Implications in Cancer Metastasis and Ageing." International Journal of Molecular Sciences 22, no. 7 (March 27, 2021): 3457. http://dx.doi.org/10.3390/ijms22073457.

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The metastasis suppressor function of NM23 proteins is widely understood. Multiple enzymatic activities of NM23 proteins have also been identified. However, relatively less known interesting aspects are being revealed from recent developments that corroborate the telomeric interactions of NM23 proteins. Telomeres are known to regulate essential physiological events such as metastasis, ageing, and cellular differentiation via inter-connected signalling pathways. Here, we review the literature on the association of NM23 proteins with telomeres or telomere-related factors, and discuss the potenti
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Xiao, Wangqun, and Jianxin Cheng. "Perceptual design method for smart industrial robots based on virtual reality and synchronous quantitative physiological signals." International Journal of Distributed Sensor Networks 16, no. 5 (May 2020): 155014772091764. http://dx.doi.org/10.1177/1550147720917646.

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In the research of industrial robot design, designing using only the perceptual thinking and creativity of an industrial designer or overemphasizing the intervention of quantitative data research in the field of emotional cognition is relatively one sided. In this article, research on how to combine the above two aspects effectively will be conducted. The aim is to present a design method which provides artistic creativity and scientific support for industrial robot design. Therefore, a method for representing perceptual image spaces of industrial robots through pictures and semantics by evalu
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Yang, Banghua, Xuelin Gu, Chao Gu, Ding Xu, and Chengcheng Fan. "Review of pathological index detection and new rehabilitation technique of drug addicts." Brain Science Advances 6, no. 2 (June 2020): 106–19. http://dx.doi.org/10.26599/bsa.2020.9050010.

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There are two major research issues with regard to detoxification; one is pathological testing of drug users and the other is rehabilitation methods and techniques. Over the years, domestic and foreign researchers have done a lot of work on pathological changes in the brain and rehabilitation techniques for drug users. This article discusses the research status of these two aspects. At present, the evaluation of brain function in drug addicts is still dominated by a single electroencephalography (EEG), near-infrared spectroscopy (NIRS), or magnetic resonance imaging scan. The multimodal physio
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De Luca, Ciro, Anna Maria Colangelo, Assunta Virtuoso, Lilia Alberghina, and Michele Papa. "Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease." International Journal of Molecular Sciences 21, no. 4 (February 24, 2020): 1539. http://dx.doi.org/10.3390/ijms21041539.

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The synaptic cleft has been vastly investigated in the last decades, leading to a novel and fascinating model of the functional and structural modifications linked to synaptic transmission and brain processing. The classic neurocentric model encompassing the neuronal pre- and post-synaptic terminals partly explains the fine-tuned plastic modifications under both pathological and physiological circumstances. Recent experimental evidence has incontrovertibly added oligodendrocytes, astrocytes, and microglia as pivotal elements for synapse formation and remodeling (tripartite synapse) in both the
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Takayanagi, Sumiko, Norman Cliff, and Penny L. Fidler. "Redundant Leading and following Zeros in Comparative Numerical Judgment." Perceptual and Motor Skills 80, no. 3 (June 1995): 819–29. http://dx.doi.org/10.2466/pms.1995.80.3.819.

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The objective was to provide a more comprehensive understanding of how people make numerical comparative judgments when digits are contained in numbers with redundant leading or following zeros, e.g., 00080 and 800.000. These sequences of numbers often appear on computer display terminals (VDT) as line numbers, but surprisingly little research has been done on this. The experiment manipulated three aspects of numerical stimuli: (1) redundant leading zeros, (2) redundant following zeros, and (3) length of string of digits. The subjects were to push one of the two button-switches to respond whet
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Stanojlovic, Milos, Jean Pierre Pallais, and Catherine M. Kotz. "Inhibition of Orexin/Hypocretin Neurons Ameliorates Elevated Physical Activity and Energy Expenditure in the A53T Mouse Model of Parkinson’s Disease." International Journal of Molecular Sciences 22, no. 2 (January 14, 2021): 795. http://dx.doi.org/10.3390/ijms22020795.

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Aside from the classical motor symptoms, Parkinson’s disease also has various non-classical symptoms. Interestingly, orexin neurons, involved in the regulation of exploratory locomotion, spontaneous physical activity, and energy expenditure, are affected in Parkinson’s. In this study, we hypothesized that Parkinson’s-disease-associated pathology affects orexin neurons and therefore impairs functions they regulate. To test this, we used a transgenic animal model of Parkinson’s, the A53T mouse. We measured body composition, exploratory locomotion, spontaneous physical activity, and energy expend
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Barsch, Friedrich, Tanja Niedermair, Andreas Mamilos, Volker H. Schmitt, David Grevenstein, Maximilian Babel, Thomas Burgoyne, Amelia Shoemark, and Christoph Brochhausen. "Physiological and Pathophysiological Aspects of Primary Cilia—A Literature Review with View on Functional and Structural Relationships in Cartilage." International Journal of Molecular Sciences 21, no. 14 (July 14, 2020): 4959. http://dx.doi.org/10.3390/ijms21144959.

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Cilia are cellular organelles that project from the cell. They occur in nearly all non-hematopoietic tissues and have different functions in different tissues. In mesenchymal tissues primary cilia play a crucial role in the adequate morphogenesis during embryological development. In mature articular cartilage, primary cilia fulfil chemo- and mechanosensitive functions to adapt the cellular mechanisms on extracellular changes and thus, maintain tissue homeostasis and morphometry. Ciliary abnormalities in osteoarthritic cartilage could represent pathophysiological relationships between ciliary d
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Munari, Enrico, Francesca R. Mariotti, Linda Quatrini, Pietro Bertoglio, Nicola Tumino, Paola Vacca, Albino Eccher, et al. "PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects." International Journal of Molecular Sciences 22, no. 10 (May 12, 2021): 5123. http://dx.doi.org/10.3390/ijms22105123.

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Immune evasion is a key strategy adopted by tumor cells to escape the immune system while promoting their survival and metastatic spreading. Indeed, several mechanisms have been developed by tumors to inhibit immune responses. PD-1 is a cell surface inhibitory receptor, which plays a major physiological role in the maintenance of peripheral tolerance. In pathological conditions, activation of the PD-1/PD-Ls signaling pathway may block immune cell activation, a mechanism exploited by tumor cells to evade the antitumor immune control. Targeting the PD-1/PD-L1 axis has represented a major breakth
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Hei, Xinhong, Wen Gao, Yichuan Wang, Lei Zhu, and Wenjiang Ji. "From Hardware to Operating System: A Static Measurement Method of Android System Based on TrustZone." Wireless Communications and Mobile Computing 2020 (September 21, 2020): 1–13. http://dx.doi.org/10.1155/2020/8816023.

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Android system has been one of the main targets of hacker attacks for a long time. At present, it is faced with security risks such as privilege escalation attacks, image tampering, and malicious programs. In view of the above risks, the current detection of the application layer can no longer guarantee the security of the Android system. The security of mobile terminals needs to be fully protected from the bottom to the top, and the consistency test of the hardware system is realized from the hardware layer of the terminal. However, there is not a complete set of security measures to ensure t
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Wintersberger, Philipp, Clemens Schartmüller, and Andreas Riener. "Attentive User Interfaces to Improve Multitasking and Take-Over Performance in Automated Driving." International Journal of Mobile Human Computer Interaction 11, no. 3 (July 2019): 40–58. http://dx.doi.org/10.4018/ijmhci.2019070103.

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Automated vehicles promise engagement in side activities, but demand drivers to resume vehicle control in Take-Over situations. This pattern of alternating tasks thus becomes an issue of sequential multitasking, and it is evident that random interruptions result in a performance drop and are further a source of stress/anxiety. To counteract such drawbacks, this article presents an attention-aware architecture for the integration of consumer devices in level-3/4 vehicles and traffic systems. The proposed solution can increase the lead time for transitions, which is useful to determine suitable
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Liao, Donghua, Dina Lelic, Feng Gao, Asbjørn Mohr Drewes, and Hans Gregersen. "Biomechanical functional and sensory modelling of the gastrointestinal tract." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 366, no. 1879 (July 2008): 3281–99. http://dx.doi.org/10.1098/rsta.2008.0091.

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The aim of this review is to describe the biomechanical, functional and sensory modelling work that can be used to integrate the physiological, anatomical and medical knowledge of the gastrointestinal (GI) system. The computational modelling in the GI tract was designed, implemented and evaluated using a series of information and communication technologies-based tools. These tools modelled the morphometry, biomechanics, functions and sensory aspects of the human GI tract. The research presented in this review is based on the virtual physiological human concept that pursues a holistic approach
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