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Rozprawy doktorskie na temat „Conjugated Biomolecules”

Autor: Grafiati
Data publikacji: 7 września 2023

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Sprawdź 18 najlepszych rozpraw doktorskich naukowych na temat „Conjugated Biomolecules”.

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1

Wigenius, Jens. "Conjugated Polyelectrolytes in Interactions with Biomolecules for Supramolecular assembly and Sensing." Doctoral thesis, Linköpings universitet, Biomolekylär och Organisk Elektronik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-54902.

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Conjugated polyelectrolytes (CP) show interesting electrical and optical properties for organic electronics as well as for life science applications. Their possibilities of supramolecular assembly with nanowire like misfolded proteins, amyloids, as well as synthetic polypeptides or DNA forming conducting or luminescent nano composites is highly interesting as being a truly bottom up approach for fabrication of OLEDs, photovoltaic’s as well as logic devices. The conformation and aggregation dependent luminescence properties from the special class of CPs, Luminescent conjugated polyelectrolytes
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Phillips, Ronald Lee III. "Poly(para-phenyleneethynylene)s probing the biological interface with biomolecular materials /." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26555.

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Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2009.<br>Committee Chair: Dr. Uwe H.F. Bunz; Committee Member: Dr. Andrew Lyon; Committee Member: Dr. Laren Tolbert; Committee Member: Dr. Nicholas Hud; Committee Member: Dr. Sherry Michele Owen. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Zhang, Yue. "Development of functional nanoparticle-biomolecule conjugates based biosensors." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/4944/.

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This thesis is composed of two parts: Part I is focused on studying how quantum dot (QD) surface small-molecule capping ligands affect its Förster resonance energy transfer (FRET) with a fluorescent protein (FP); Part II is focused on developing an ultrasensitve DNA sensing technology by combining magnetic nanoparticle (MNP) and enzymatic signal amplification. Part I The FRET between a CdSe/ZnS core/shell QD capped with three different small-molecule ligands and a hexa-histidine (His6)-tagged FP (mCherry) has been studied. Results show that small-molecule ligands strongly affect the FRET behav
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Elfwing, Anders. "On decoration of biomolecular scaffolds with a conjugated polyelectrolyte." Doctoral thesis, Linköpings universitet, Biomolekylär och Organisk Elektronik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-141675.

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Biotemplating is the art of using a biological structure as a scaffold which is decorated with a functional material. In this fashion the structures will gain new functionalities and biotemplating offers a simple route of mass-producing mesoscopic material with new interesting properties. Biological structures are abundant and come in a great variety of elaborate and due to their natural origin they could be more suitable for interaction with biological systems than wholly synthetic materials. Conducting polymers are a novel class of material which was developed just 40 years ago and are well
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Herland, Anna. "Conjugated Polymers, Amyloid Detection and Assembly of Biomolecular Nanowires." Doctoral thesis, Linköping : Biomolecular and Organic Electronics, Department of Physics, Chemistry and Biology, Linköping University, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/tek1117s.pdf.

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Mekapothula, Swapna. "Gold nanoparticle-biomolecule conjugates synthesis, properties, cellular interactions and cytotoxicity studies /." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/5641.

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Thesis (M.S.)--University of Missouri-Columbia, 2008.<br>"May 2008" The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Includes bibliographical references.
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7

Ogbodu, Racheal O. "Photophysicochemical properties and in vitro photodynamic therapy activities of zinc phthalocyanine conjugates with biomolecules and single-walled carbon nanotubes." Thesis, Rhodes University, 2015. http://hdl.handle.net/10962/d1017924.

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The synthesis, photophysicochemcial properties, in vitro dark toxicity and photodynamic therapy (PDT) activities of different derivatives of zinc phthalocyanine (ZnPc) conjugates with biomolecules (folic acid, bovine serum albumin (BSA), ascorbic acid, uridine or spermine) and single-walled carbon nanotubes (SWCNTs) are presented in this work. The fluorescence quantum yields (ΦF) (Subscript F) of the ZnPc derivatives or ZnPc-biomolecule conjugates remained relatively the same as compared to the precursor Pcs. Slight increases were observed in the ΦF (Subscript F) values of conjugates containin
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8

Winger, Theodore Medard. "Synthetic phospholipid-peptide conjugates : biomolecular building blocks for receptor activating structures." Thesis, Georgia Institute of Technology, 1994. http://hdl.handle.net/1853/9505.

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Maione, Silvana. "Polymers and peptide-polymer conjugates as bioactive platforms and carriers for the encapsulation of biomolecules." Doctoral thesis, Universitat Politècnica de Catalunya, 2017. http://hdl.handle.net/10803/460833.

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In the last decade, conductive polymers have received great interest in both scientific and technological levels due to the electroactive properties exhibited by these materials. For this reason, the main aim of this Doctoral Thesis is to study the applications of some conducting polymers, mainly derived from polythiophene, in the field of biomedicine and biotechnology. According to the objectives proposed in this Document, different studies focused on the preparation and characterization of graft copolymers have been carried out using macromonomers formed by oligo-thiophenes to which PEG cha
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10

Stumper, Anne [Verfasser]. "Designing potent PDT drug candidates - development of crucial linking strategies for biomolecule-metal-complex-conjugates / Anne Stumper." Ulm : Universität Ulm, 2018. http://d-nb.info/1150301856/34.

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11

Gupta, Prachi. "SYNTHESIS AND CHARACTERIZATION OF ANTIOXIDANT CONJUGATED POLY(ΒETA-AMINO ESTER) MICRO/NANOGELS FOR THE SUPPRESSION OF OXIDATIVE STRESS". UKnowledge, 2016. http://uknowledge.uky.edu/cme_etds/58.

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Oxidative stress is a pathophysiological condition defined by an increased production of reactive oxygen species (ROS), which can result in the growth arrest of cells followed by cell disintegration or necrosis. A number of small molecule antioxidants (e.g. curcumin, quercetin and resveratrol) are capable of directly scavenging ROS, thereby short-circuiting the self-propagating oxidative stress state. However, poor solubility and rapid 1st pass metabolism results in overall low bioavailability and acts as a barrier for its use as a drug to suppress oxidative stress efficiently. To overcome thi
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12

"Photophysics of Symmetric and Asymmetric Cyanines in Solution and Conjugated to Biomolecules." Doctoral diss., 2017. http://hdl.handle.net/2286/R.I.44159.

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abstract: Fluorescence spectroscopy is a powerful tool for biophysical studies due to its high sensitivity and broad availability. It is possible to detect fluorescence from single molecules allowing researchers to see the behavior of subpopulations whose presence is obscured by “bulk” collection methods. The fluorescent probes used in these experiments are affected by the solution and macromolecular environments they are in. A misunderstanding of a probe’s photophysics can lead researchers to assign observed behavior to biomolecules, when in fact the probe is responsible. On the other han
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13

KUAN, WEI-CHIH, and 官暐摯. "Study on the preparation of biomolecules conjugated magnetic particles and their application for cell isolating and immobilization of GST fusion protein." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/jb7t72.

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Kogot, Joshua Michael. "Surface assembly and intracellular delivery of biomolecule conjugated nanomaterials." 2008. http://etd.lib.fsu.edu/theses/available/etd-11052008-165903.

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Thesis (Ph. D.)--Florida State University, 2008.<br>Advisor: Geoffrey Strouse, Florida State University, College of Arts and Sciences, Dept. of Chemistry and Biochemistry. Title and description from dissertation home page (viewed Mar. 12, 2009). Document formatted into pages; contains xi, 86 pages. Includes bibliographical references.
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15

Liu, Yi-Hsin, and 劉怡欣. "Development of Nanomaterials-Biomolecular Conjugates and Their Applications in Biological Systems." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/78581612262487162656.

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博士<br>國立臺灣師範大學<br>化學系<br>99<br>The applications of nanomaterials-biomolecular conjugates in DNA detection and RNA interference (RNAi) have led to ever-growing developments in the past decades. In this work, we have developed a new technique used fluorescent silica nanotubes for simple and sensitive DNA detection. The quantum dots embedded silica nanotubes (QD-SNTs) were fabricated by a sol-gel reaction using anodic aluminum oxide (AAO) as a template. The fluorescent QD-SNTs of different colors were then immobilized with single stranded DNA and used as nanoprobes to detect dye-labeled target DN
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16

Wu, Chung-Shu, and 吳中書. "Regulation of Catalytic Activity via the Biomolecular Interactions Based on Enzyme–Nanoparticle Conjugates." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/86248682816934289322.

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博士<br>國立交通大學<br>材料科學與工程學系奈米科技碩博士班<br>99<br>Protein surface recognition provides an appealing tool to regulate protein–protein interactions and enzymatic activities in the field of biological science. We are interested in using nanoparticle (NP) to bind enzyme surfaces through multivalent interactions and then engineer the protein properties. In this study, we have investigated the activity of the enzyme–NP conjugates and demonstrated that adsorbing enzyme onto NPs significantly increased its enzymatic activity. We ascribe this event of the enzymatic reactions by kinetic and thermodynamic studi
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17

Cheng, Chieh, and 鄭捷. "Designs and Synthesis of Nanoparticle–Biomolecule Conjugates for Biological Application: Controlled-Release Drug Delivery System, Antibacterial, and Wound Dressing." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/9b64e7.

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18

(11205204), Spencer D. Lindeman. "DESIGN, SYNTHESIS, AND PRECLINICAL EVALUATION OF LIGAND-TARGETED CONJUGATES FOR CANCER RADIOTHERANOSTICS." Thesis, 2021.

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For any drug candidate to be approved by the U.S. Food and Drug Administration, it must meet strict standards for safety and efficacy. While the field of nuclear medicine is over 100 years old, traditional methods such as external beams or systematic administration have rarely met these standards or have limited application. Ligand-targeted therapy and diagnostics, or “theranostics,” has emerged in the past several decades as an exciting field that offers new possibilities to design drugs that are both safe and effective. When applied to nuclear medicine, the field of ligand-targeted radioacti
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