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1

García-Calderón, Clara B., Meritxell García-Quintanilla, Josep Casadesús, and Francisco Ramos-Morales. "Virulence attenuation in Salmonella enterica rcsC mutants with constitutive activation of the Rcs system." Microbiology 151, no. 2 (2005): 579–88. http://dx.doi.org/10.1099/mic.0.27520-0.

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Mutations in rcsC that result in constitutive colanic acid capsule synthesis were obtained in Salmonella enterica serovar Typhimurium. Most rcsC alleles were dominant; however, recessive rcsC alleles were also found, in agreement with the postulated double role (positive and negative) of RcsC on the activation of the RcsB/C phosphorelay system. Salmonella rcsC mutants with constitutive activation of the Rcs system are severely attenuated for virulence in BALB/c mice and their degree of attenuation correlates with the level of Rcs activation. Partial relief of attenuation by a gmm mutation indi
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2

Hazan-Halevy, Inbal, David Harris, Zhiming Liu, et al. "STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells." Blood 115, no. 14 (2010): 2852–63. http://dx.doi.org/10.1182/blood-2009-10-230060.

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Abstract Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western hemisphere, but its pathogenesis is still poorly understood. Constitutive tyrosine phosphorylation (p) of signal transducer and activator of transcription (STAT) 3 occurs in several solid tumors and hematologic malignancies. In CLL, however, STAT3 is constitutively phosphorylated on serine 727, not tyrosine 705, residues. Because the biologic significance of serine pSTAT3 in CLL is not known, we studied peripheral blood cells of 106 patients with CLL and found that, although tyrosine pSTAT3 was inducible, se
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3

Adan, Roger A. H. "Constitutive Receptor Activity series Endogenous inverse agonists and constitutive receptor activity in the melanocortin system." Trends in Pharmacological Sciences 27, no. 4 (2006): 183–86. http://dx.doi.org/10.1016/j.tips.2006.02.002.

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Aerts, Dirk, Tom Verhaeghe, Marjan De Mey, Tom Desmet, and Wim Soetaert. "A constitutive expression system for high-throughput screening." Engineering in Life Sciences 11, no. 1 (2010): 10–19. http://dx.doi.org/10.1002/elsc.201000065.

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Kirkby, Nicholas S., Melissa V. Chan, Anne K. Zaiss та ін. "Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways". Proceedings of the National Academy of Sciences 113, № 2 (2015): 434–39. http://dx.doi.org/10.1073/pnas.1517642113.

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Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs). However, COX-2 is also constitutively expressed, in the absence of overt inflammation, with a specific tissue distribution that includes the kidney, gastrointestinal tract, brain, and thymus. Constitutive COX-2 expression is therapeutically important because NSAIDs cause cardiovascular and renal side effects in otherwise healthy individuals. These side effects are now of major concern globally. However, the pathways driving constit
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6

Hamilton, Ruth, Mike Siva-Jothy, and Mike Boots. "Two arms are better than one: parasite variation leads to combined inducible and constitutive innate immune responses." Proceedings of the Royal Society B: Biological Sciences 275, no. 1637 (2008): 937–45. http://dx.doi.org/10.1098/rspb.2007.1574.

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Parasites represent a major threat to all organisms which has led to the evolution of an array of complex and effective defence mechanisms. Common to both vertebrates and invertebrates are innate immune mechanisms that can be either constitutively expressed or induced on exposure to infection. In nature, we find that a combination of both induced and constitutive responses are employed by vertebrates, invertebrates and, to an extent, plants when they are exposed to a parasite. Here we use a simple within-host model motivated by the insect immune system, consisting of both constitutive and indu
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7

Cheng, Tao. "Numerical Simulation for the Deformation of Composite Wall Insulation System." Advanced Materials Research 374-377 (October 2011): 187–90. http://dx.doi.org/10.4028/www.scientific.net/amr.374-377.187.

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The nonlinear constitutive relations of clay are investigated with different initial stress conditions. Two series of triaxial compression tests are performed, respectively after consolidation and isotropic consolidation. On the basis of the framework of ~ model, a uniform nonlinear constitutive model is proposed by fitting of the test data. With the average slope of the unloading-reloading curve selected as the unloading modulus, the unloading function is constructed as the loading-unloading criterion. Moreover, a comparison of the experimental stress-strain curves with the predicted results
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8

Singer, John T., Ryan T. Phennicie, Matthew J. Sullivan, Laura A. Porter, Valerie J. Shaffer, and Carol H. Kim. "Broad-Host-Range Plasmids for Red Fluorescent Protein Labeling of Gram-Negative Bacteria for Use in the Zebrafish Model System." Applied and Environmental Microbiology 76, no. 11 (2010): 3467–74. http://dx.doi.org/10.1128/aem.01679-09.

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ABSTRACT To observe real-time interactions between green fluorescent protein-labeled immune cells and invading bacteria in the zebrafish (Danio rerio), a series of plasmids was constructed for the red fluorescent protein (RFP) labeling of a variety of fish and human pathogens. The aim of this study was to create a collection of plasmids that would express RFP pigments both constitutively and under tac promoter regulation and that would be nontoxic and broadly transmissible to a variety of Gram-negative bacteria. DNA fragments encoding the RFP dimeric (d), monomeric (m), and tandem dimeric (td)
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9

Bednář, Miloš. "The constitutive values of fair play." AUC KINANTHROPOLOGICA 59, no. 2 (2024): 79–92. http://dx.doi.org/10.14712/23366052.2023.5.

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Fair play as a phenomenon of sporting life is present even if only in the form of small acts or gestures in most competitions; its absence is present in cases of foul play. The daily press comments its presence or absence every day in, and not only in the sports sections. Both the public and experts discuss acts from so called grey zone (forms of gamesmanship). Deciding unequivocally on the moral quality of a diverse range of actions, attitudes or statements requires clarity about the values underpinning fair play. Our aim is therefore to find the constitutive values of fair play by examining
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10

Murjiyanto, Raden. "Legal Protection of the Registered Trademark Owner in the Constitutive System (First to File) in Indonesia." SHS Web of Conferences 54 (2018): 06014. http://dx.doi.org/10.1051/shsconf/20185406014.

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Since the enactment of Law Number 19 of 1992 on Trademarks that had been amended last with the enactment of Law Number 20 of 2016 on Trademarks, it applies the Constitutive System (First to File) which is a change from the old system of the Declarative System (First to Use). Therefore, the legal protection is determined by a registration. However, there are still many lawsuit cases of trademark cancellation. Based on the Constitutive System, the right is granted to the first registrant. Some cases are based on a lawsuit from a party who feels as the owner of the trademark, but registered by an
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11

Kasperavičius, Algis. "Constitutive Parliament and its speakers." Lietuvos istorijos studijos 12 (December 29, 2003): 36–46. http://dx.doi.org/10.15388/lis.2003.37174.

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On April of 1920, elected Constitutive Parliament term continued till the 6th of October 1922. It worked strenuously; there took place 257 ordinary meetings, which continued for some hours every day. They often ended in the next morning. The most important task of the Constitutive Parliament was to prepare a permanent Constitution of the Lithuanian Republic, but it performed other rules' publishing functions too. It performed the control of executive government institutions of all levels. The education of parliament members was much better than the middle education of Lithuanian citizens, but
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12

Nijenhuis, Wouter A. J., Julia Oosterom, and Roger A. H. Adan. "AgRP(83–132) Acts as an Inverse Agonist on the Human-Melanocortin-4 Receptor." Molecular Endocrinology 15, no. 1 (2001): 164–71. http://dx.doi.org/10.1210/mend.15.1.0578.

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Abstract The central melanocortin (MC) system has been demonstrated to act downstream of leptin in the regulation of body weight. The system comprises α-MSH, which acts as agonist, and agouti-related protein (AgRP), which acts as antagonist at the MC3 and MC4 receptors (MC3R and MC4R). This property suggests that MCR activity is tightly regulated and that opposing signals are integrated at the receptor level. We here propose another level of regulation within the melanocortin system by showing that the human (h) MC4R displays constitutive activity in vitro as assayed by adenylyl cyclase (AC) a
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13

Delgado-Martín, Josemaría, and Leonardo Velasco. "An efficient dsRNA constitutive expression system in Escherichia coli." Applied Microbiology and Biotechnology 105, no. 16-17 (2021): 6381–93. http://dx.doi.org/10.1007/s00253-021-11494-6.

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14

Suthaus, Jan, Anna Tillmann, Inken Lorenzen, Elena Bulanova, Stefan Rose-John, and Jürgen Scheller. "Forced Homo- and Heterodimerization of All gp130-Type Receptor Complexes Leads to Constitutive Ligand-independent Signaling and Cytokine-independent Growth." Molecular Biology of the Cell 21, no. 15 (2010): 2797–807. http://dx.doi.org/10.1091/mbc.e10-03-0240.

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Naturally ligand independent constitutively active gp130 variants were described to be responsible for inflammatory hepatocellular adenomas. Recently, we genetically engineered a ligand-independent constitutively active gp130 variant based on homodimerization of Jun leucine zippers. Because also heterodimeric complexes within the gp130 family may have tumorigenic potential, we seek to generate ligand-independent constitutively active heterodimers for all known gp130-receptor complexes based on IL-15/IL-15Rα-sushi fusion proteins. Ligand-independent heterodimerization of gp130 with WSX-1, LIFR,
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15

von Zastrow, M., and J. D. Castle. "Protein sorting among two distinct export pathways occurs from the content of maturing exocrine storage granules." Journal of Cell Biology 105, no. 6 (1987): 2675–84. http://dx.doi.org/10.1083/jcb.105.6.2675.

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We have developed a method for separating purified parotid secretory granules according to their degree of maturation, and we have used this method to examine the relationship between granule formation and stimulus-independent (constitutive) protein secretion. Constitutive export of pulse-labeled secretory proteins occurs almost entirely after their appearance in newly formed granules, and this secretion can be resolved kinetically into two distinct components. Later-phase secretion is the more prominent component and, according to kinetic and compositional criteria, appears to result from bas
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16

Bodega, Guillermo, Celia Hernández, Isabel Suárez, Montserrat Martín, and Benjamín Fernández. "HSP70 Constitutive Expression in Rat Central Nervous System from Postnatal Development to Maturity." Journal of Histochemistry & Cytochemistry 50, no. 9 (2002): 1161–68. http://dx.doi.org/10.1177/002215540205000902.

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We studied the level of the basal (constitutive) HSP70 expression (inducible and constitutive forms) in the central nervous system (CNS) of male and female rats from the postnatal period to maturity. HSP70 levels were analyzed by immunoblotting in five different areas (cortex, hippocampus, hypothalamus, cerebellum, and spinal cord). The highest levels of HSP70 were found in juvenile rats and decreased progressively until reaching baseline levels between 2 and 4 months. A slight and nonsignificant increase in aged (2-year-old) rats compared with adult subjects was observed in some cerebral area
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17

Ma, Yi Ping, Jie Fu, Han Zhang, et al. "Research on Early Warning System for Plastic Shrinkage Cracking of Cement Mortar Based on Constitutive Equations." Key Engineering Materials 861 (September 2020): 438–45. http://dx.doi.org/10.4028/www.scientific.net/kem.861.438.

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Aiming at the plastic shrinkage cracking of cement mortar, the constitutive equations of it in laboratory were established by testing plastic tensile strength, plastic capillary shrinkage stress and water loss evaporation rate of mortar under different composition parameters, environmental parameters, initial structural parameters and constraints condition parameters. And the early warning system of it was explored. The results showed that the seven-element constitutive equation of plain mortar and the nine-element constitutive equation of mortar with polyvinyl alcohol (PVA) fiber can effectiv
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18

Waspiah, Waspiah. "RENEWAL OF THE CONSTITUTIVE NATIONAL LAW SYSTEM IN INDUSTRIAL DESIGN." Jurnal Hukum Progresif 10, no. 2 (2022): 86–98. http://dx.doi.org/10.14710/jhp.10.2.86-98.

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The regulation of industrial design in Indonesia is still experiencing several challenges, one of which is regarding the legal system. This paper aims to analyze the reform of the constitutive national legal system on industrial design in Indonesia. This paper confirms that the requirements for legal protection with a Constitutive system on industrial design by MSMEs required by law, if they are still used in the current era, where world developments are very fast, do not reflect the national legal system, so that what should be based on Pancasila as a legal ideal. An alternative step in bridg
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19

Chun, C. K., and S. B. Dong. "Shear Constitutive Relations for Laminated Anisotropic Shells and Plates: Part II—Vibrations of Composite Cylinders." Journal of Applied Mechanics 59, no. 2 (1992): 380–89. http://dx.doi.org/10.1115/1.2899531.

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In Part I of this paper, a system of shear constitutive relations was proposed for a first-order shear deformation theory of laminated anisotropic plates and shells. For laminated anisotropic structures, these shear constitutive equations involved the concept of generalized shear planes. Herein, an extensive parametric study is presented to assess the modeling capability of these shear constitutive relations in a class of laminated composite and sandwich cylinders. Classical theory results are also given in order to fully understand the influence of anisotropy on the accuracy and ranges of val
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20

Dear, J., Z. Shi, and J. Lin. "An efficient numerical integration system for stiff unified constitutive equations for metal forming applications." IOP Conference Series: Materials Science and Engineering 1270, no. 1 (2022): 012008. http://dx.doi.org/10.1088/1757-899x/1270/1/012008.

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Unified constitutive equations have been developed in recent years to predict viscoplastic flow and microstructural evolution of metal alloys for metal forming applications. These equations can be implemented into commercial FE code, such as ABAQUS and PAMSTAMP, to predict mechanical and physical properties of materials in a wide range of metal forming processes. These equations are normally stiff and need significant computer CPU time to solve. In this research, a series of numerical analyses are performed to investigate the difficulties within MATLAB of solving these stiff unified constituti
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HELAL, MOHAMED S. "Anarchy, ordering principles and the constitutive regime of the international system." Global Constitutionalism 8, no. 3 (2019): 470–505. http://dx.doi.org/10.1017/s204538171900011x.

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Abstract:Anarchy is the conceptual cornerstone of international relations theory and international law scholarship. Anarchy is described as the ordering principle of the international system, it is used as a variable that explains state behaviour, and the international legal order is depicted as anarchic and decentralised. This article questions this privileged status of anarchy. It challenges the designation of anarchy as the ‘ordering principle’ of the international system, and proposes an alternative theoretical construct – the Constitutive Regime of the International System – that performs
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22

Cao, Da Zhi, Zhi Hua Zhao, and Ge Xue Ren. "Dynamic Modeling of Viscoelastic Body in Multibody System." Applied Mechanics and Materials 105-107 (September 2011): 587–94. http://dx.doi.org/10.4028/www.scientific.net/amm.105-107.587.

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Dynamic equations of viscoelastic bodies with fractional constitutive are derived base on the principle of virtual work and the theory of continuum mechanics. The three-dimensional fractional derivative viscoelastic constitutive model is implemented into the flexible multibody system (FMBS), using the 3D solid element based on the absolute nodal coordinate formulation (ANCF), which can exactly describe the geometric nonlinearities due to large rotation and large deformation. The BDF time integration scheme in conjunction with the Grünwald approximation of fractional derivative and the Newton-R
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FUJIMURA, Tomohiro, Toshio TSUTA, Takeshi IWAMOTO, and Osamu KANEKO. "3D IN VIVO IDENTIFICATION SYSTEM FOR CONSTITUTIVE PARAMETERS OF SKIN." Biomechanisms 15 (2000): 17–30. http://dx.doi.org/10.3951/biomechanisms.15.17.

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Miller, Stephen G., and Hsiao-Ping H. Moore. "Biochemical analysis of constitutive secretion in a semiintact cell system." Cell Biophysics 19, no. 1 (1991): 35–43. http://dx.doi.org/10.1007/bf02989877.

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Ibraimov, Abyt, Stalbek Akhunbayev, and Orozali Uzakov. "Human Chromosomal Q-heterochromatin Regions as a System." Biomedical Research and Clinical Reviews 6, no. 4 (2022): 01–05. http://dx.doi.org/10.31579/2692-9406/106.

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The eukaryotic genome consists of the two forms of chromatin: euchromatin and heterochromatin. The DNA of euchromatin contains the gene portion of the genome, while heterochromatin is represented predominantly from non-coding repetitive nucleotide sequences that do not encode proteins or enzymes. In higher eukaryotes, some part of the non-coding, highly repetitive nucleotide sequences were transformed into complex forms of DNA organization as chromosomal constitutive heterochromatin regions. There are two types of constitutive heterochromatin: C- and Q-heterochromatin. C-heterochromatin is fou
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Nitas, Michalis, and Traianos V. Yioultsis. "Electromagnetic parameter retrieval technique utilizing eigenvalue analysis and field averaging." Journal of Applied Physics 131, no. 11 (2022): 114902. http://dx.doi.org/10.1063/5.0083559.

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In this paper, a fully numerical homogenization technique is presented for the retrieval of the effective constitutive parameters of a periodic composite medium. Based on the eigensolution returned by the utilized field-flux FEM formulation, a proper field averaging process of the field components is proposed over specific paths of the periodic unit cell of an arbitrary structure. Subsequently, the constitutive relations for every eigenmode supported by the medium are derived, forming a linear system of equations. The solution of this system returns a set of fifteen effective constitutive para
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Xiao, Yang, Xiaoyong Luo, Minliang Xing, Zhen Pan, Junfeng Cheng, and Jinhong Liu. "Simplified Analytical Methods for Prefabricated Concrete Wall Panel Building System with Alveolar-Type Joints." Buildings 13, no. 5 (2023): 1177. http://dx.doi.org/10.3390/buildings13051177.

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This paper presents a type of prefabricated concrete wall panel building system with novel flexible alveolar-type joints, which has the advantages of fast assembly and controllable quality. Seven alveolar-type joint specimens were designed and fabricated to investigate the influence of the axial compression ratio, the size of the joint (in the interface contact area), and the strength of the mortar on the joints’ performance. The shear–slip constitutive model of the alveolar-type joints was established on this basis. The accuracy of the constitutive model was verified by comparing two full-sca
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Wang, Qing Wu, Mao Pang, and Shi Hui Zhang. "Crystallographic Constitutive Models for Single Crystal Superalloys." Advanced Materials Research 197-198 (February 2011): 1381–88. http://dx.doi.org/10.4028/www.scientific.net/amr.197-198.1381.

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Single crystal nickel base superalloys, such as Chinese material DD6 have been used in gas turbine blade in China more and more widely. In order to make better use of single crystal superalloys with many excellencies, constitutive models have been developed. In this paper, general method of crystallographic constitutive modeling was summarizes and a new constitutive model, based on crystallographic theory was proposed with phenomenological models' advantages. Based on crystallographic slip system principle, the basic slip-based viscoplasticity theory equations were set up on 12 octahedral slip
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Xie, Jiuming, Shiyu Wang, Zhongbao Cui, Jin Wu, and Xuejun Zhou. "Research on Anisotropic Viscoelastic Constitutive Model of Compression Molding for CFRP." Materials 13, no. 10 (2020): 2277. http://dx.doi.org/10.3390/ma13102277.

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The carbon-fiber-reinforced polymer (CFRP) is a mainstream material for lightweight products from the end of the 20th century to the present day. Its compression molding process has obvious advantages in mass production. This paper attempts to establish the constitutive models of compression molding of the CFRP materials and study their mechanism. Based on anisotropic linear elastic mechanics, viscoelastic mechanics, and thermodynamics, as well as the Maxwell viscoelastic constitutive model, we first establish the constitutive model of thermorheologically simple CFRP materials (TSMs). Then, co
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Politis, Nicholas J., and Denis J. Politis. "Development of a computational optimisation system to determine constitutive equation constants for metal alloys." Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications 233, no. 6 (2017): 1166–83. http://dx.doi.org/10.1177/1464420717728752.

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Simulations of metal forming processes typically use constitutive equations to describe material properties over a wide range of temperatures and strain rates. Classically, determining a set of values for the large number of constants present in more complex constitutive models presented great difficulty to researchers. In this paper, an algorithmic method of determining the constants of such constitutive equations is presented. The Genetic Algorithm implementation utilising MATLAB is described, and example fits to experimental data are presented. A study is performed to improve the performanc
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Gao, Jun Li, and Meng Xi Zhang. "Stability Analysis of Landfill Liner System Based on Numerical Simulation." Advanced Materials Research 446-449 (January 2012): 1637–40. http://dx.doi.org/10.4028/www.scientific.net/amr.446-449.1637.

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Although ABAQUS is one of the most powerful non-linearly finite element software, it is lack of interface Duncan-Chang constitutive model, which is one of the generally used soil numerical method in China and worldwide. Subsequently, ABAQUS can not widely used in soil numerical method. To improve this situation, a new interface Duncan-Chang constitutive model was developed based on the preliminary direct shear test results through secondary development. Combined with practical engineering, the efficient model was established. Compared with smooth geomembrane/geotextile interface, the shear str
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Linden, Katrina J., and Judy Callis. "The ubiquitin system affects agronomic plant traits." Journal of Biological Chemistry 295, no. 40 (2020): 13940–55. http://dx.doi.org/10.1074/jbc.rev120.011303.

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In a single vascular plant species, the ubiquitin system consists of thousands of different proteins involved in attaching ubiquitin to substrates, recognizing or processing ubiquitinated proteins, or constituting or regulating the 26S proteasome. The ubiquitin system affects plant health, reproduction, and responses to the environment, processes that impact important agronomic traits. Here we summarize three agronomic traits influenced by ubiquitination: induction of flowering, seed size, and pathogen responses. Specifically, we review how the ubiquitin system affects expression of genes or a
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Deraredj Nadim, Wissem, Séverine Chaumont-Dubel, Fahima Madouri, et al. "Physical interaction between neurofibromin and serotonin 5-HT6 receptor promotes receptor constitutive activity." Proceedings of the National Academy of Sciences 113, no. 43 (2016): 12310–15. http://dx.doi.org/10.1073/pnas.1600914113.

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Active G protein-coupled receptor (GPCR) conformations not only are promoted by agonists but also occur in their absence, leading to constitutive activity. Association of GPCRs with intracellular protein partners might be one of the mechanisms underlying GPCR constitutive activity. Here, we show that serotonin 5 hydroxytryptamine 6 (5-HT6) receptor constitutively activates the Gs/adenylyl cyclase pathway in various cell types, including neurons. Constitutive activity is strongly reduced by silencing expression of the Ras-GTPase activating protein (Ras-GAP) neurofibromin, a 5-HT6 receptor partn
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Srivastava, Ankit. "Causality and passivity in elastodynamics." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 471, no. 2180 (2015): 20150256. http://dx.doi.org/10.1098/rspa.2015.0256.

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What are the constraints placed on the constitutive tensors of elastodynamics by the requirements that the linear elastodynamic system under consideration be both causal (effects succeed causes) and passive (system does not produce energy)? The analogous question has been tackled in other areas but in the case of elastodynamics its treatment is complicated by the higher order tensorial nature of its constitutive relations. In this paper, we clarify the effect of these constraints on highly general forms of the elastodynamic constitutive relations. We show that the satisfaction of passivity (an
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Zhang, Xueli, Ran Meng, Haina Wang, and Jie Xing. "Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors." Planta Medica 86, no. 12 (2020): 867–75. http://dx.doi.org/10.1055/a-1178-0852.

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Abstract Artemisia annua tea is a popular dosage form used to treat and prevent malaria in some developing countries. However, repeated drinking leads to an obviously decreased efficacy, which may be related to the induction of metabolizing enzymes by artemisinin. In the present study, the ability of different components in A. annua to activate the pregnane X receptor and constitutive androstane receptor was evaluated by the dual luciferase reporter gene system. The changes in mRNA and protein expression of CYP3A4 and CYP2B6 were determined by quantitative real-time PCR and Western blotting. R
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O'Reilly, Erin K., and Kenneth N. Kreuzer. "Isolation of SOS Constitutive Mutants of Escherichia coli." Journal of Bacteriology 186, no. 21 (2004): 7149–60. http://dx.doi.org/10.1128/jb.186.21.7149-7160.2004.

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ABSTRACT The bacterial SOS regulon is strongly induced in response to DNA damage from exogenous agents such as UV radiation and nalidixic acid. However, certain mutants with defects in DNA replication, recombination, or repair exhibit a partially constitutive SOS response. These mutants presumably suffer frequent replication fork failure, or perhaps they have difficulty rescuing forks that failed due to endogenous sources of DNA damage. In an effort to understand more clearly the endogenous sources of DNA damage and the nature of replication fork failure and rescue, we undertook a systematic s
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37

Auvinen, Tero. "At the Intersection of Sovereignty and Biopolitics: The Di-Polaric Spatializations of Money." Foucault Studies, no. 9 (September 1, 2010): 5. http://dx.doi.org/10.22439/fs.v0i9.3055.

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The paper explores the incentive structures and the structurally rigid social hierarchies inherent in the polarizing logic of modern credit money and the mutual constitution of money’s sovereign and biopolitical dimensions. It is argued that the monetary system constitutes a major transitory channel for the logic of financial capital to transcend the limitations of sovereign spaces and to transform itself into a biopolitical force. The relationship between the material and the subjective – or the sovereign and the biopolitical – dimensions of money is seen as di-polaric rather than di-chotomic
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38

Bertucci, Monica, Ky Ariano, Meg Zumsteg, and Paul Schweiger. "Engineering a tunable bicistronic TetR autoregulation expression system in Gluconobacter oxydans." PeerJ 10 (July 19, 2022): e13639. http://dx.doi.org/10.7717/peerj.13639.

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Acetic acid bacteria are well-known for their ability to incompletely oxidize their carbon sources. Many of the products of these oxidations find industrial uses. Metabolic engineering of acetic acid bacteria would improve production efficiency and yield by allowing controllable gene expression. However, the molecular tools necessary for regulating gene expression have only recently started being explored. To this end the ability of the activation-dependent Plux system and two constitutive repression Ptet systems were examined for their ability to modulate gene expression in Gluconobacter oxyd
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39

Ai, Lijia, Peng Li, Hongwei Yuan, Chunrong Tian, Xiaolian Qiang, and Tao Fu. "Investigation of Constitutive Models for Pressure Monitoring of Viscoelastic–Hyperelastic Composite Structures." Polymers 17, no. 5 (2025): 647. https://doi.org/10.3390/polym17050647.

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To ensure ammunition safety, a protective structure and pressure detection system are essential; however, there is a lack of an accurate constitutive model to describe the mechanical response characteristics of protective structures composed of various polymer materials. In this work, a constitutive model for the composite structure based on the superposition principle is successfully constructed derived from the quasi-static compression behavior of rigid polyurethane foam (RPUF), silicone rubber foam (SRF), and flexible pressure sensors (FPSs) through experimental investigations. The constitu
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40

Gasulla, Francisco, Eva M. del Campo, Leonardo M. Casano, and Alfredo Guéra. "Advances in Understanding of Desiccation Tolerance of Lichens and Lichen-Forming Algae." Plants 10, no. 4 (2021): 807. http://dx.doi.org/10.3390/plants10040807.

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Lichens are symbiotic associations (holobionts) established between fungi (mycobionts) and certain groups of cyanobacteria or unicellular green algae (photobionts). This symbiotic association has been essential in the colonization of terrestrial dry habitats. Lichens possess key mechanisms involved in desiccation tolerance (DT) that are constitutively present such as high amounts of polyols, LEA proteins, HSPs, a powerful antioxidant system, thylakoidal oligogalactolipids, etc. This strategy allows them to be always ready to survive drastic changes in their water content. However, several stud
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41

Tokeson, J. P., S. Garges, and S. Adhya. "Further inducibility of a constitutive system: ultrainduction of the gal operon." Journal of Bacteriology 173, no. 7 (1991): 2319–27. http://dx.doi.org/10.1128/jb.173.7.2319-2327.1991.

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42

苏比伊努尔·, 库尔班. "Research on the Constitutive Elements of the Third Party Repayment System." Open Journal of Legal Science 12, no. 02 (2024): 914–21. http://dx.doi.org/10.12677/ojls.2024.122133.

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43

VASCONCELLOS, ÁUREA ROSAS, ROBERTO LUZZI, and LEOPOLDO S. GARCIA-COLIN. "MEMORY-DEPENDENT CONSTITUTIVE EQUATIONS IN INFORMATIONAL STATISTICAL THERMODYNAMICS." International Journal of Modern Physics B 09, no. 16 (1995): 1933–44. http://dx.doi.org/10.1142/s0217979295000781.

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The nonequilibrium Statistical Operator Method, seemingly contained within the scope of Jaynes’ Predictive Statistical Mechanics, provides a foundation for irreversible thermodynamics in what is called Informational Statistical Thermodynamics, and within it a way of deriving generalized constitutive equations which contain non-localities on space. Here we present a derivation of these equations of evolution describing how memory effects are incorporated into the theory. We show that the memory kernels in the kinetic coefficients and relaxation times can be expressed in terms of an infinite ser
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44

Stutz, Hans Henning, Peter Norlyk, Kenneth Sørensen, Lars Vabbersgaard Andersen, Kenny Kataoka Sørensen, and Johan Clausen. "Finite element modelling of an energy-geomembrane underground pumped hydroelectric energy storage system." E3S Web of Conferences 205 (2020): 07001. http://dx.doi.org/10.1051/e3sconf/202020507001.

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The increasing need for energy storage technology has led to a massive interest in novel energy storage methods. The energy geomembrane system is such a novel energy storage method. The concept of the system is briefly introduced, and a holistic numerical model of the system is presented. The model uses advanced finite-element techniques to model the energy storage system using fluid cavity elements. The developed geomembrane energy system is modelled with different constitutive models to represent the soil behaviour: a linear elastic model, a nonlinear Mohr-Coulomb model, and a hypoplastic co
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Liu, Xinyu, and Pengling Li. "Utilization of Constitutive Elements in Unjust Legal Actions." Pacific International Journal 7, no. 1 (2024): 179–89. http://dx.doi.org/10.55014/pij.v7i1.537.

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The system that deals with unfairness in civil transactions in China has been continuously improved as a result of the dynamic nature of the market economy. The objective is to deter inequitable conditions and transactions in civil exchanges, guaranteeing that contractual parties participate in commerce founded on principles of equity and free will. This paper examines the fundamental components of unjust legal actions as outlined in the Chinese Civil Code. It investigates how these elements are applied and evolved in legal practice, and draws comparisons with similar legal systems worldwide,
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Iglesias Neves, Henrique, Tuanny Fernanda Pereira, Ezra Yagil, and Beny Spira. "Ugp and PitA Participate in the Selection of PHO-Constitutive Mutants." Journal of Bacteriology 197, no. 8 (2015): 1378–85. http://dx.doi.org/10.1128/jb.02566-14.

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ABSTRACTMutations that cause the constitutive expression of the PHO regulon ofEscherichia colioccur either in thepstoperon or in thephoRgene, which encode, respectively, a high-affinity Pitransport system and a histidine kinase sensor protein. These mutations are normally selected on glycerol-2-phosphate (G2P) as the carbon source in the presence of excess Pi. The emergence of early PHO-constitutive mutants, which appear after growth for up to 48 h on selective medium, depends on the presence ofphoA, which codes for a periplasmic alkaline phosphatase, while late mutants, which appear after 48
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Chen, Xiao An, Shun Cheng Song, and Ting Hui Wang. "Measurements of Shearing Property of High N Alloy Steel at Super High Strain Rates." Advanced Materials Research 413 (December 2011): 42–45. http://dx.doi.org/10.4028/www.scientific.net/amr.413.42.

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In order to obtain the dynamic shearing property of high N alloy steel, the plugging test was performed by using the improved Hopkinson pressure bar system. As dynamic shearing strengths, the dynamic shearing energies during plugging process of two type high N alloy steels were determined from the shearing constitutive relationship at different super high strain rates. According to the theory of dislocation dynamics in Seeger equation, a dynamic shearing damage constitutive relationship was established and the different parameters of this material were determined by using the curve fitting met
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Zhang, Yong Kang, Yu Long Li, and Hong Bing Zhang. "A Method to Identify Bird Constitutive Model and its Parameters." Applied Mechanics and Materials 302 (February 2013): 686–93. http://dx.doi.org/10.4028/www.scientific.net/amm.302.686.

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Identification of a bird constitutive model and its parameters is a very difficult work in bird-impact coupling solution. In order to identify the constitutive model and the parameters simultaneously, an inversion analytic model for the bird material parameters is given based on penalty function method and nonlinear optimization principle, and then combining the model preferential criterion proposed in this paper, the identification system of the bird constitutive model is established with ANSYS Parametric Design Language (APDL). Finally, the feasibility and practicability of this identificati
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Zylberman, Ariel. "The Public Form of Law: Kant on the Second-Personal Constitution of Freedom." Kantian Review 21, no. 1 (2016): 101–26. http://dx.doi.org/10.1017/s1369415415000321.

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AbstractThe two standard interpretations of Kant’s view of the relationship between external freedom and public law make one of the terms a means for the production of the other: either public law is justified as a means to external freedom, or external freedom is justified as a means for producing a system of public law. This article defends an alternative, constitutive interpretation: public law is justified because it is partly constitutive of external freedom. The constitutive view requires conceiving of external freedom in a novel, second-personal way, that is, as an irreducibly relationa
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Furuta, T., K. Katou, S. Itoh, K. Tachibana, S. Ishikawa, and H. Katsuragi. "Geometry-dependent constitutive law for granular slow frictional drag." International Journal of Modern Physics B 31, no. 10 (2017): 1742006. http://dx.doi.org/10.1142/s0217979217420061.

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Frictional constitutive law for very slow vertical withdrawing of a thin rod from a granular bed is experimentally studied. Using a very precise creep meter, geometry-dependent granular frictional constitutive law is particularly examined. In some previous works, a dimensionless number [Formula: see text] has been used to characterize granular frictional constitutive laws, where [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] are the shear strain rate, grain diameter, confining pressure, and bulk density of granular bed, respectively. It has been consider
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