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1

Buchkovich, K. J., and E. B. Ziff. "Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells." Molecular Biology of the Cell 5, no. 11 (1994): 1225–41. http://dx.doi.org/10.1091/mbc.5.11.1225.

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In the absence of serum, nerve growth factor (NGF) promotes the survival and differentiation of the PC12 pheochromocytoma cell line. In the presence of serum, NGF acts primarily as a differentiation factor and negative regulator of cell cycling. To investigate NGF control of cell cycling, we have analyzed the regulation of cyclin dependent kinases during PC12 cell differentiation. NGF treatment leads to a reduction in the steady-state protein levels of p33cdk2 and p34cdc2, two key regulators of cell cycle progression. The decrease in p33cdk2 and p34cdc2 coincides with a decrease in the enzymat
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2

Traganos, Frank. "Cycling without Cyclins." Cell Cycle 3, no. 1 (2004): 31–33. http://dx.doi.org/10.4161/cc.3.1.608.

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Holding, Cathy. "Cycling without cyclins." Genome Biology 5 (2004): spotlight—20040824–01. http://dx.doi.org/10.1186/gb-spotlight-20040824-01.

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Diehl, J. Alan. "Cycling to Cancer with Cyclin D1." Cancer Biology & Therapy 1, no. 3 (2002): 226–31. http://dx.doi.org/10.4161/cbt.72.

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Resnitzky, D., M. Gossen, H. Bujard, and S. I. Reed. "Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system." Molecular and Cellular Biology 14, no. 3 (1994): 1669–79. http://dx.doi.org/10.1128/mcb.14.3.1669-1679.1994.

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Conditional overexpression of human cyclins B1, D1, and E was accomplished by using a synthetic cDNA expression system based on the Escherichia coli tetracycline repressor. After induction of these cyclins in asynchronous Rat-1 fibroblasts, a decrease in the length of the G1 interval was observed for cyclins D1 and E, consistent with an acceleration of the G1/S phase transition. We observed, in addition, a compensatory lengthening of S phase and G2 so that the mean cell cycle length in populations constitutively expressing these cyclins was unchanged relative to those of their uninduced counte
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Resnitzky, D., M. Gossen, H. Bujard, and S. I. Reed. "Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system." Molecular and Cellular Biology 14, no. 3 (1994): 1669–79. http://dx.doi.org/10.1128/mcb.14.3.1669.

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Conditional overexpression of human cyclins B1, D1, and E was accomplished by using a synthetic cDNA expression system based on the Escherichia coli tetracycline repressor. After induction of these cyclins in asynchronous Rat-1 fibroblasts, a decrease in the length of the G1 interval was observed for cyclins D1 and E, consistent with an acceleration of the G1/S phase transition. We observed, in addition, a compensatory lengthening of S phase and G2 so that the mean cell cycle length in populations constitutively expressing these cyclins was unchanged relative to those of their uninduced counte
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7

Ježek, Jan, Daniel G. J. Smethurst, David C. Stieg, et al. "Cyclin C: The Story of a Non-Cycling Cyclin." Biology 8, no. 1 (2019): 3. http://dx.doi.org/10.3390/biology8010003.

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The class I cyclin family is a well-studied group of structurally conserved proteins that interact with their associated cyclin-dependent kinases (Cdks) to regulate different stages of cell cycle progression depending on their oscillating expression levels. However, the role of class II cyclins, which primarily act as transcription factors and whose expression remains constant throughout the cell cycle, is less well understood. As a classic example of a transcriptional cyclin, cyclin C forms a regulatory sub-complex with its partner kinase Cdk8 and two accessory subunits Med12 and Med13 called
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8

Yi, Xie, and Li Bing. "The Transcription Express Characteristics of Several Genes in the Process of Bombyx mori Ovarian Carcinoma." Advanced Materials Research 796 (September 2013): 39–42. http://dx.doi.org/10.4028/www.scientific.net/amr.796.39.

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Bombyx mori cell line (BmN) comes fromBombyx moriovary cell subculture. In order to study the change of several genes transcription in the process ofBombyx moriovary cells primary culture and subculture, we usedBombyx moriovary organizations and BmN cell lines as research materials, used Real Time fluorescent quantitative RT-PCR to detect cyclin gene family (CyclinA, CyclinB, CyclinB3, CyclinE, CyclinL1), p53 and Telomerase genes transcription level in the ovary and BmN cell lines, and took Actin3 gene as reference to dispose the results. The results showed that in theBombyx moriBmN cell lines
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9

Ehrhardt, Harald, Catarina Castro Alves, Franziska Wachter, and Irmela Jeremias. "TRAIL Preferentially Affects Cell Cycle-Arrested Tumor Cells Including Stem- and Progenitor Cells From Patients with Acute Lymphoblastic Leukemia." Blood 120, no. 21 (2012): 1879. http://dx.doi.org/10.1182/blood.v120.21.1879.1879.

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Abstract Abstract 1879 Leukemic stem- and progenitor cells exhibit low cycling activity which might represent a major cause for their increased treatment resistance. TRAIL (TNF-related apoptosis inducing ligand) is a novel putative anticancer drug currently in phase I and II clinical testing. We recently showed that TRAIL is able to address stem- and progenitor cells from patients with acute lymphoblastic leukemia (ALL) in xenotransplantation assays (Alves et al., Blood 2012,119,4224). As stem- and progenitor cells are often non-cycling, we asked here, whether TRAIL is able to address resting
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10

Cogswell, J. P., M. M. Godlevski, M. Bonham, J. Bisi, and L. Babiss. "Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoter." Molecular and Cellular Biology 15, no. 5 (1995): 2782–90. http://dx.doi.org/10.1128/mcb.15.5.2782.

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Progression through the somatic cell cycle requires the temporal regulation of cyclin gene expression and cyclin protein turnover. One of the best-characterized examples of this regulation is seen for the B-type cyclins. These cyclins and their catalytic component, cdc2, have been shown to mediate both the entry into and maintenance of mitosis. The cyclin B1 gene has been shown to be expressed between the late S and G2 phases of the cell cycle, while the protein is degraded specifically at interphase via ubiquitination. To understand the molecular basis for transcriptional regulation of the cy
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11

Wang, Jia-Hao, Yan Li, Shou-Long Deng, Yi-Xun Liu, Zheng-Xing Lian, and Kun Yu. "Recent Research Advances in Mitosis during Mammalian Gametogenesis." Cells 8, no. 6 (2019): 567. http://dx.doi.org/10.3390/cells8060567.

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Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has been made by showing that cyclins/cyclin-dependent kinase (CDK) have roles in the regulation of meiosis. In addition, more functional signaling molecules have been discovered in mitosis. Growing evidence has also indicated that miRNAs influence cell cycling. In this review, we focus on specific genes,
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12

Cox, Peter. "Cycling." Transfers 2, no. 1 (2012): 159–64. http://dx.doi.org/10.3167/trans.2012.020113.

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The mechanized mobility practices that came to dominate road use in the twentieth century—using cars, motorbikes, and bicycles—have been notable for the concurrent development of accompanying print literatures in the form of magazines and newspapers. The developmental history of each mode can be told through a number of distinct lenses, each revealing a part of the story of the mobility technology in use. In the context of a renaissance in cycling, there is an emergence of a new style of bicycle magazine that breaks the mould of previous journals.
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13

Cortez, Angela N., and Dana H. Kotler. "Cycling." Physical Medicine and Rehabilitation Clinics of North America 33, no. 1 (2022): i. http://dx.doi.org/10.1016/s1047-9651(21)00092-9.

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14

Reiser, Raoul, Jon Watt, and Michael Peterson. "Cycling." Sports Biomechanics 2, no. 2 (2003): 237–49. http://dx.doi.org/10.1080/14763140308522821.

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15

Soniat, Katherine. "Cycling." Women's Review of Books 21, no. 2 (2003): 16. http://dx.doi.org/10.2307/4024300.

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16

&NA;. "Cycling." Back Letter 5, no. 3 (1991): 4. http://dx.doi.org/10.1097/00130561-199105030-00005.

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17

Dixon, Warren, and Matthew Bellman. "Cycling." Mechanical Engineering 138, no. 09 (2016): S3—S7. http://dx.doi.org/10.1115/1.2016-sep-4.

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This article presents an overview of a control systems perspective. An electric field when applied to yield functional tasks is called as functional electrical stimulation (FES). FES is commonly prescribed as a treatment for various neurological disorders. Given the existence of regions in the crank cycle where it is inefficient to produce torque, a motor can be included as another torque source. FES control of the muscles yields cadence tracking in torque efficient regions, while the motor yields cadence tracking when it is efficient for the limbs to produce torque. The inclusion of a motor e
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18

Welberg, Leonie. "Cycling vesicles for a cycling SCN." Nature Reviews Neuroscience 11, no. 1 (2009): 5. http://dx.doi.org/10.1038/nrn2799.

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19

Bouftas, Nora, and Katja Wassmann. "Cycling through mammalian meiosis: B-type cyclins in oocytes." Cell Cycle 18, no. 14 (2019): 1537–48. http://dx.doi.org/10.1080/15384101.2019.1632139.

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20

Abrieu, A., T. Brassac, S. Galas, D. Fisher, J. C. Labbe, and M. Doree. "The Polo-like kinase Plx1 is a component of the MPF amplification loop at the G2/M-phase transition of the cell cycle in Xenopus eggs." Journal of Cell Science 111, no. 12 (1998): 1751–57. http://dx.doi.org/10.1242/jcs.111.12.1751.

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We have investigated whether Plx1, a kinase recently shown to phosphorylate cdc25c in vitro, is required for activation of cdc25c at the G2/M-phase transition of the cell cycle in Xenopus. Using immunodepletion or the mere addition of an antibody against the C terminus of Plx1, which suppressed its activation (not its activity) at G2/M, we show that Plx1 activity is required for activation of cyclin B-cdc2 kinase in both interphase egg extracts receiving recombinant cyclin B, and cycling extracts that spontaneously oscillate between interphase and mitosis. Furthermore, a positive feedback loop
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21

Vogetseder, Alexander, Thomas Palan, Desa Bacic, Brigitte Kaissling, and Michel Le Hir. "Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney." American Journal of Physiology-Cell Physiology 292, no. 2 (2007): C807—C813. http://dx.doi.org/10.1152/ajpcell.00301.2006.

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We searched for evidence for a contribution of stem cells in growth of the proximal S3 segments of healthy rats. According to the stem cell model, stem cells are undifferentiated and slow cycling; the bulk of cycling cells are transit amplifying, rapidly cycling cells. We show the following. 1) By continuous application of a thymidine analog (ThA) for 7 days, S3 proximal epithelial cells in healthy kidneys display a high-cycling rate. 2) Slow-cycling cells, identified by lack of ThA uptake during 14 days of continuous ThA application up to death and by expression of the cell cycle protein Ki67
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22

Arkesteijn, Marco, Simon Jobson, James Hopker, and Louis Passfield. "The Effect of Cycling Intensity on Cycling Economy During Seated and Standing Cycling." International Journal of Sports Physiology and Performance 11, no. 7 (2016): 907–12. http://dx.doi.org/10.1123/ijspp.2015-0441.

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Background:Previous research has shown that cycling in a standing position reduces cycling economy compared with seated cycling. It is unknown whether the cycling intensity moderates the reduction in cycling economy while standing.Purpose:The aim was to determine whether the negative effect of standing on cycling economy would be decreased at a higher intensity.Methods:Ten cyclists cycled in 8 different conditions. Each condition was either at an intensity of 50% or 70% of maximal aerobic power at a gradient of 4% or 8% and in the seated or standing cycling position. Cycling economy and muscle
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23

Che, Hui, Gang Li, Hai-Ying Sun, Guo-Sheng Xiao, Yan Wang, and Gui-Rong Li. "Roles of store-operated Ca2+ channels in regulating cell cycling and migration of human cardiac c-kit+ progenitor cells." American Journal of Physiology-Heart and Circulatory Physiology 309, no. 10 (2015): H1772—H1781. http://dx.doi.org/10.1152/ajpheart.00260.2015.

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Cardiac c-kit+ progenitor cells are important for maintaining cardiac homeostasis and can potentially contribute to myocardial repair. However, cellular physiology of human cardiac c-kit+ progenitor cells is not well understood. The present study investigates the functional store-operated Ca2+ entry (SOCE) channels and the potential role in regulating cell cycling and migration using confocal microscopy, RT-PCR, Western blot, coimmunoprecipitation, cell proliferation, and migration assays. We found that SOCE channels mediated Ca2+ influx, and TRPC1, STIM1, and Orai1 were involved in the format
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24

Derks, Wouter, and Olaf Bergmann. "Cycling Cardiomyocytes." Circulation Research 128, no. 2 (2021): 169–71. http://dx.doi.org/10.1161/circresaha.120.318574.

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Stoffers, Manuel. "Cycling Cultures." Transfers 1, no. 1 (2011): 147–54. http://dx.doi.org/10.3167/trans.2011.010111.

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Dave Horton, Paul Rosen, and Peter Cox (ed.), Cycling and Society (Aldershot: Ashgate, 2007), xvi + 205 pp., €77.00.A.A. Albert de la Bruhèze and F.C.A. Veraart, Fietsverkeer in praktijk en beleid in de twintigste eeuw: overeenkomsten en verschillen in fietsgebruik in Amsterdam, Eindhoven, Enschede, Zuidoost-Limburg, Antwerpen, Manchester, Kopenhagen, Hannover en Basel (Den Haag: Ministerie van Verkeer en Waterstaat/Stichting Historie der Techniek, 1999), 240 pp.Anne-Katrin Ebert, Radelnde Nationen: Die Geschichte des Fahrrads in Deutschland und den Niederlanden bis 1940 (Frankfurt a.M.: Campu
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26

Glover, David M. "…still cycling." Journal of Cell Science 114, no. 22 (2001): 3953–54. http://dx.doi.org/10.1242/jcs.114.22.3953.

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Burn, Bob. "Cycling Digits." Mathematical Gazette 75, no. 472 (1991): 154. http://dx.doi.org/10.2307/3620242.

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Goodlin, Gabrielle T., Lindsey Steinbeck, Deborah Bergfeld, and Alexandria Haselhorst. "Adaptive Cycling." Physical Medicine and Rehabilitation Clinics of North America 33, no. 1 (2022): 31–43. http://dx.doi.org/10.1016/j.pmr.2021.08.003.

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Goodlin, Gabrielle T., Lindsey Steinbeck, Deborah Bergfeld, and Alexandria Haselhorst. "Adaptive Cycling." Physical Medicine and Rehabilitation Clinics of North America 33, no. 1 (2022): 45–60. http://dx.doi.org/10.1016/j.pmr.2021.08.004.

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Cortez, Angela N., and Dana H. Kotler. "Cycling Medicine." Physical Medicine and Rehabilitation Clinics of North America 33, no. 1 (2022): xv—xvi. http://dx.doi.org/10.1016/j.pmr.2021.09.001.

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31

Gann, Joshua J., Grant M. Tinsley, and Paul M. La Bounty. "Weight Cycling." Strength and Conditioning Journal 37, no. 5 (2015): 105–11. http://dx.doi.org/10.1519/ssc.0000000000000168.

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32

Burns, C. Conner. "Serious Cycling." Medicine &amp Science in Sports &amp Exercise 28, no. 4 (1996): 537. http://dx.doi.org/10.1097/00005768-199604000-00023.

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Carmichael, Chris, Edmund R. Burke, and Michele Hobson. "Fitness Cycling." Medicine & Science in Sports & Exercise 27, no. 8 (1995): 1229. http://dx.doi.org/10.1249/00005768-199508000-00023.

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DELLNITZ, MICHAEL, MICHAEL FIELD, MARTIN GOLUBITSKY, JUN MA, and ANDREAS HOHMANN. "CYCLING CHAOS." International Journal of Bifurcation and Chaos 05, no. 04 (1995): 1243–47. http://dx.doi.org/10.1142/s0218127495000909.

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Dileep Sai, T., Dr N.Venkatram, and A. Veda. "Free Cycling." International Journal of Engineering & Technology 7, no. 2.7 (2018): 913. http://dx.doi.org/10.14419/ijet.v7i2.7.11095.

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The essential objective of our venture is to collect an in general open handedness site which diminishes misuse (squander), spares fabricated products, at the same time empowers our individuals to be get profited from the control of a bigger zone for no income. For specific made merchandise there can be various selectors, so based on the fundamental concern or by the prerequisite of the buyer they made products are advertised. Our approach is to put forward a present day innovation that will permit people to reuse the fabricated merchandise in a simple way. It’s totally non-profitable and base
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36

Hauglid, Christopher, Jace Morganstein, and Amie Kim. "Cardiovascular-Cycling." Medicine & Science in Sports & Exercise 54, no. 9S (2022): 87. http://dx.doi.org/10.1249/01.mss.0000876124.47666.cb.

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Monsen, Rita Black. "Children cycling." Journal of Pediatric Nursing 17, no. 6 (2002): 439–40. http://dx.doi.org/10.1053/jpdn.2002.128952.

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38

Alderton, Gemma K. "Fractal cycling." Nature Reviews Molecular Cell Biology 8, no. 11 (2007): 851. http://dx.doi.org/10.1038/nrm2284.

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39

Locke, S. "Road cycling." British Journal of Sports Medicine 40, no. 11 (2006): 950. http://dx.doi.org/10.1136/bjsm.2006.028688.

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40

Adamo, Gregory. "City Cycling." Journal of Urban Technology 21, no. 3 (2014): 103–5. http://dx.doi.org/10.1080/10630732.2014.954410.

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Burgess, Darren J. "Lethal cycling." Nature Reviews Drug Discovery 9, no. 9 (2010): 682. http://dx.doi.org/10.1038/nrd3260.

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42

Dellnitz, M., M. Field, M. Golubitsky, A. Hohmann, and Jun Ma. "Cycling chaos." IEEE Transactions on Circuits and Systems I: Fundamental Theory and Applications 42, no. 10 (1995): 821–23. http://dx.doi.org/10.1109/81.473592.

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Brownell, Kelly D. "Weight cycling." American Journal of Clinical Nutrition 49, no. 5 (1989): 937. http://dx.doi.org/10.1093/ajcn/49.5.937.

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Marks, Julian M. "Theoretical cycling." Physics World 20, no. 1 (2007): 16. http://dx.doi.org/10.1088/2058-7058/20/1/26.

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45

Ringrose, Leonie, and Renato Paro. "Cycling silence." Nature 412, no. 6846 (2001): 493–94. http://dx.doi.org/10.1038/35087692.

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46

Rybicki, Edward. "Cycling essays." Nature 337, no. 6205 (1989): 316. http://dx.doi.org/10.1038/337316b0.

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Whitfield, Mike. "Elementary cycling." Nature 386, no. 6620 (1997): 35–36. http://dx.doi.org/10.1038/386035a0.

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48

Vuori, Ilkka. "Promoting Cycling." Clinical Journal of Sport Medicine 21, no. 6 (2011): 542–44. http://dx.doi.org/10.1097/01.jsm.0000407931.13102.0b.

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49

Venables, M. "SportsTech: Cycling." Engineering & Technology 8, no. 6 (2013): 84–85. http://dx.doi.org/10.1049/et.2013.0615.

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Ramsay, Maurice. "Cycling record." Physics World 18, no. 11 (2005): 22. http://dx.doi.org/10.1088/2058-7058/18/11/30.

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