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Artykuły w czasopismach na temat „Cystic fibrosis in children”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 30 lipca 2024

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1

Staab, D. "Cystic fibrosis -- therapeutic challenge in cystic fibrosis children." European Journal of Endocrinology 151, Suppl_1 (August 1, 2004): S77—S80. http://dx.doi.org/10.1530/eje.0.151s077.

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Cystic fibrosis (CF) is the most common autosomal recessive disease with fatal outcome in Caucasians with a frequency of 1 in 2500 life births. It is caused by mutations in a single gene on the long arm of chromosome 7 encoding a protein called the cystic fibrosis transmembrane regulator (CFTR). The defect in CFTR leads to pathological changes in all organs with mucus-secretory glands, e.g. airways, pancreas, gut, biliary tract, vas deferens and sweat glands. Despite impressive advances in understanding the molecular basis of the disease, life expectancy is still limited in CF and chronic infe
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2

Maffessanti, Mario, Manila Candusso, Franca Brizzi, and Francesco Piovesana. "Cystic Fibrosis in Children." Journal of Thoracic Imaging 11, no. 1 (1996): 27–38. http://dx.doi.org/10.1097/00005382-199601110-00002.

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Slieker, Martyn G., Anne G. M. Schilder, Cuno S. P. M. Uiterwaal, and Cornelis K. van der Ent. "Children With Cystic Fibrosis." Archives of Otolaryngology–Head & Neck Surgery 128, no. 11 (November 1, 2002): 1245. http://dx.doi.org/10.1001/archotol.128.11.1245.

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Littlewood, J. M. "Fibrosing colonopathy in children with cystic fibrosis." Postgraduate Medical Journal 72, no. 845 (March 1, 1996): 129–30. http://dx.doi.org/10.1136/pgmj.72.845.129.

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Reichard, Kirk W., Charles D. Vinocur, Maria Franco, Kristin L. Crisci, Jonathan A. Flick, Deborah F. Billmire, Daniel V. Schidlow, and William H. Weintraub. "Fibrosing colonopathy in children with cystic fibrosis." Journal of Pediatric Surgery 32, no. 2 (February 1997): 237–42. http://dx.doi.org/10.1016/s0022-3468(97)90186-x.

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Klimov, L. Ya, S. V. Dolbnya, E. I. Kondratyeva, A. A. Dyatlova, E. A. Enina, V. A. Kuryaninova, A. N. Kasyanova, et al. "Vitamin d status during winter months among children and adolescents with cystic fibrosis living in southern Russia." Medical Council, no. 2 (February 16, 2019): 240–49. http://dx.doi.org/10.21518/2079-701x-2019-2-240-249.

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The article presents the results of vitamin D tests in children with cystic fibrosis and in healthy children living in the South of Russia. The study showed the high prevalence of vitamin D deficiency and inadequate levels in patients with cystic fibrosis (86.7%). 25(OH) D level characterizing the vitamin D status decreases progressively in patients and healthy children. With regard to the above mentioned, it is significantly lower in patients with cystic fibrosis than in healthy children in all age periods. The correlation between the serum calcidiol level and the age of patients with cystic
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7

Amarri, Sergio, Marilyn Harding, W. Andrew Coward, T. John Evans, and Lawrence T. Weaver. "13C and H2 Breath Tests to Study Extent and Site of Starch Digestion in Children with Cystic Fibrosis." Journal of Pediatric Gastroenterology and Nutrition 29, no. 3 (September 1999): 327–31. http://dx.doi.org/10.1002/j.1536-4801.1999.tb02423.x.

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ABSTRACTBackground:Starch is an important source of energy for children with cystic fibrosis, but little is known about their capacity to digest it.Methods:A 13C breath test was used to measure starch digestion and oxidation in 16 children with cystic fibrosis (median [range] age, 7.9 [4‐15] years; 7 girls, 9 boys) and 5 normal healthy control subjects (median age, 8.3 [7‐13] years; 3 girls, 2 boys). A test meal of 13C flour and lactulose was consumed and breath samples were obtained half‐hourly thereafter for 6 hours to measure 13C enrichment by isotope ratio mass spectrometry and H2 by elect
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8

Burlutskaya, A. V., V. Yu Brisin, A. V. Statova, O. Yu Zenkina, and J. V. Pisotskaya. "Targeted Therapy for Cystic Fibrosis in Children." Innovative Medicine of Kuban, no. 4 (November 17, 2023): 142–47. http://dx.doi.org/10.35401/2541-9897-2023-8-4-142-147.

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A mutation in the CFTR gene causes the malfunctioning of the CFTR protein that is located on the apical membrane of epithelial cells and functions as a chloride channel. The discovery of CFTR modulators is an advance in cystic fibrosis treatment.Objective: To analyze modern Russian and foreign literature on targeted therapy for cystic fibrosis in children. We also describe the history of cystic fibrosis, evolution in its diagnosis and treatment, and mechanisms behind targeted therapy for cystic fibrosis.
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9

Daftari, Tahereh, Naser Havaei, Mandana Rezaei, and Babak Ghalibaf. "Occupational performance status and reliability of the Canadian Occupational Performance Measure in children with cystic fibrosis." International Journal of Therapy and Rehabilitation 27, no. 6 (June 2, 2020): 1–9. http://dx.doi.org/10.12968/ijtr.2019.0088.

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Background/Aims Cystic fibrosis affects the respiratory system and may interfere with an individual's occupational performance. This study intended to evaluate the reliability of the Canadian Occupational Performance Measure in children with cystic fibrosis and to compare the occupational performance of children with cystic fibrosis to that of healthy participants. Methods A total of 21 children with cystic fibrosis were included in the reliability and comparison phases of this study and 30 healthy children were recruited for the comparison phase. The Canadian Occupational Performance Measure
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10

Stapleton, Denise, Deborah Kerr, Lyle Gurrin, Jill Sherriff, and Peter Sly. "Height and Weight Fail to Detect Early Signs of Malnutrition in Children With Cystic Fibrosis." Journal of Pediatric Gastroenterology and Nutrition 33, no. 3 (September 2001): 319–25. http://dx.doi.org/10.1002/j.1536-4801.2001.tb07464.x.

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ABSTRACTBackgroundMany children with cystic fibrosis grow poorly and are malnourished. This study was undertaken to determine whether extensive anthropometry could detect early signs of malnutrition in prepubertal children with cystic fibrosis to prevent deficits in height and weight.MethodsHeight, weight, six skin folds (triceps, subscapular, supraspinale, abdominal, front thigh, and medial calf) and five girths (arm relaxed, forearm, chest, thigh, and calf) were measured in a cross‐sectional study of children aged 6 to 11 years with cystic fibrosis.ResultsThe children with cystic fibrosis we
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11

Ritivoiu, Mirela-Elena, Cristina Manuela Drăgoi, Dumitru Matei, Iustina Violeta Stan, Alina Crenguţa Nicolae, Mihai Craiu, Ion-Bogdan Dumitrescu, and Alina Angelica Ciolpan. "Current and Future Therapeutic Approaches of Exocrine Pancreatic Insufficiency in Children with Cystic Fibrosis in the Era of Personalized Medicine." Pharmaceutics 15, no. 1 (January 3, 2023): 162. http://dx.doi.org/10.3390/pharmaceutics15010162.

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This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of new therapies, such as cystic fibrosis transmembrane conductance regulator modulator therapies. Few articles evaluate the efficacy of pancreatic enzyme replacement therapy in the pediatric population, and most studies also included children and adults with cystic fibrosis. Approximately 85% of cystic fibrosis patients have exocrine pancreatic i
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12

Bulatov, V. P., and N. V. Rylova. "COMPLEX ULTRASOUND CHARACTERISTICS OF THE PANCREAS IN CHILDREN WITH CYSTIC FIBROSIS." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 63, no. 5 (November 20, 2018): 155–61. http://dx.doi.org/10.21508/1027-4065-2018-63-5-155-161.

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Objective:to evaluate the condition of the pancreas in children with cystic fibrosis using complex ultrasound.We examined 80 children from 3 to 18 years: 50 children with mixed cystic fibrosis and 30 conditionally healthy children. The complex ultrasound consisted of gray scale US, color dopplerography, energy dopplerography and pulse-wave dopplerography.Results.A complex study of such parameters as splenic vein diameter, volume and linear blood flow with postprandial response help to obtain more complete picture of pancreatic damage in children with cystic fibrosis. This highly sensitive and
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13

Bellini, Sarah Gunnell, Perry Chapman, Kayla Szendre, Catherine McDonald, Nicole Williams, Lauren Hopkin, Dennis Eggett, and April Dean. "Changes in handgrip strength in children with cystic fibrosis compared to children without cystic fibrosis." Clinical Nutrition ESPEN 42 (April 2021): 206–11. http://dx.doi.org/10.1016/j.clnesp.2021.01.038.

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14

Kirk, J. M., and A. Westwood. "Interpretation of Sweat Sodium Results—The Effect of Patient Age." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 26, no. 1 (January 1989): 38–43. http://dx.doi.org/10.1177/000456328902600105.

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In a retrospective study of sweat tests performed on 650 patients, sweat sodium was shown to increase with age in children without cystic fibrosis. The clearest separation of children with and without cystic fibrosis was in the youngest infants, while the highest proportion of repeatedly equivocal results was in the older children. Applying age-related reference ranges did not resolve the equivocal cases without also missing some cases of cystic fibrosis.
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15

Walker, Lynn S., Melissa B. Ford, and William D. Donald. "Cystic Fibrosis and Family Stress: Effects of Age and Severity of Illness." Pediatrics 79, no. 2 (February 1, 1987): 239–46. http://dx.doi.org/10.1542/peds.79.2.239.

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Stress and adjustment in mothers of children with cystic fibrosis was compared with that in a control group of mothers of healthy children. Mothers of children in four age groups were included: preschool, middle childhood, early adolescence, and late adolescence. Mothers of children with cystic fibrosis did not report significantly higher levels of stress than did the control group mothers; nor did they report greater feelings of inadequacy as parents. However, mothers of children with cystic fibrosis in two age groups, preschool and early adolescence, scored higher on a measure of depression
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16

Panova, L. V., E. S. Ovsyankina, E. I. Kondratyeva, and E. D. Nikolaeva. "Tailored approach to the treatment of pulmonary mycobacteriosis in patients with cystic fibrosis." Voprosy praktičeskoj pediatrii 17, no. 3 (2022): 141–46. http://dx.doi.org/10.20953/1817-7646-2022-3-141-146.

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Diagnosis, treatment, and follow-up of children with cystic fibrosis and pulmonary mycobacteriosis pose a challenge due to lack of scientifically justified clinical recommendations on patient management. The article provides two clinical observations, illustrating a personalized approach to administration of antibacterial therapy to children with cystic fibrosis and bronchopulmonary comorbidity caused by nontuberculous mycobacteria. Clinical, microbiological, and radiological study results were interpreted to define treatment tactics. Key words: children, cystic fibrosis, pulmonary mycobacteri
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17

Dolbnya, S. V., A. A. Dyatlova, L. Ya Klimov, E. I. Kondratyeva, I. N. Zakharova та E. A. Enina. "Relationship between vitamin D sufficiency and interferon-γ levels in children with chronic lung diseases". Meditsinskiy sovet = Medical Council, № 12 (27 липня 2023): 231–39. http://dx.doi.org/10.21518/ms2023-221.

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Introduction. The role and mechanism of the effect of vitamin D on the course of chronic lung diseases in children are not yet fully understood. In particular, there are not enough studies on the effect of vitamin D status on the production of interferon-γ (IFN-γ) in children with cystic fibrosis and bronchial asthma.Aim. To analyse the changes in IFN-γ levels in children with cystic fibrosis and bronchial asthma according to the serum 25(OH)D level before and during cholecalciferol supplementation.Materials and methods. A total of 114 children (aged from 3 months to 18 years old) were examine
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18

Tsyunchyk, Y. G. "The early diagnosis of hepatobiliary lesions in children with cystic fibrosis." CHILD`S HEALTH 18, no. 4 (July 14, 2023): 277–82. http://dx.doi.org/10.22141/2224-0551.18.4.2023.1600.

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Background. An increase in life expectancy of patients with cystic fibrosis contributes to the formation of severe patho­logy of the hepatobiliary system, leading to the development of fatal biliary cirrhosis. The purpose was to prospectively assess the predictive value of a combination of serum liver enzymes, ultrasound liver parameters and transient elastography for diagnosis of clinically significant liver fibrosis. Materials and methods. We enrolled 108 children aged 0–17 years with cystic fibrosis. The fibrosis stage was determined using transient elastography on FibroScan® 502 (Echosens,
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19

Gardner, Lisa. "Teaching young children about cystic fibrosis." Paediatric Nursing 16, no. 4 (May 2004): 34–36. http://dx.doi.org/10.7748/paed.16.4.34.s26.

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Gardner, Lisa. "Teaching young children about cystic fibrosis." Paediatric Care 16, no. 4 (May 2004): 34–36. http://dx.doi.org/10.7748/paed2004.05.16.4.34.c917.

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21

David, Tj. "Cystic fibrosis in children and adults." Journal of the Royal Society of Medicine 104, no. 1_suppl (July 2011): 1. http://dx.doi.org/10.1258/jrsm.2011.s11110.

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David, T. J. "Cystic fibrosis in children and adults." Journal of the Royal Society of Medicine 105, no. 2_suppl (June 2012): 1. http://dx.doi.org/10.1258/jrsm.2012.12s011.

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23

Kovell, Lara C., Jiangxia Wang, Stacey L. Ishman, Pamela L. Zeitlin, and Emily F. Boss. "Cystic Fibrosis and Sinusitis in Children." Otolaryngology–Head and Neck Surgery 145, no. 1 (March 10, 2011): 146–53. http://dx.doi.org/10.1177/0194599811400816.

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Gerdes, Jeffrey S., and Shirley Murphy. "Cystic Fibrosis in Pueblo Indian Children." Clinical Pediatrics 24, no. 2 (February 1985): 104–6. http://dx.doi.org/10.1177/000992288502400209.

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MACDONALD, NONI E., ROBERT F. MORRIS, and PIERRE H. BEAUDRY. "Varicella in children with cystic fibrosis." Pediatric Infectious Disease Journal 6, no. 4 (April 1987): 414–16. http://dx.doi.org/10.1097/00006454-198704000-00014.

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Aktay, Atiye N., Steven L. Werlin, and Heidi E. Hoeppner. "Electrogastrography in children with cystic fibrosis." Gastroenterology 118, no. 4 (April 2000): A1158—A1159. http://dx.doi.org/10.1016/s0016-5085(00)80454-0.

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David, T. J. "Cystic Fibrosis in Children and Adults." Paediatric Respiratory Reviews 14 (May 2013): 1. http://dx.doi.org/10.1016/j.prrv.2013.01.004.

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David, T. J. "Cystic Fibrosis in Children and Adults." Paediatric Respiratory Reviews 15 (June 2014): 1. http://dx.doi.org/10.1016/j.prrv.2014.04.001.

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Kumru, B., N. Emiralioğlu, and H. Gökmen Ozel. "Malnutrition in children with cystic fibrosis." Clinical Nutrition 37 (September 2018): S90—S91. http://dx.doi.org/10.1016/j.clnu.2018.06.1353.

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Singh, Meenu, Rajendra Prasad, and Lata Kumar. "Cystic fibrosis in north Indian children." Indian Journal of Pediatrics 69, no. 7 (July 2002): 627–29. http://dx.doi.org/10.1007/bf02722693.

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David, T. J. "Cystic fibrosis in children and adults." Paediatric Respiratory Reviews 16 (October 2015): 1. http://dx.doi.org/10.1016/j.prrv.2015.07.005.

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David, T. J. "Cystic Fibrosis in Children and Adults." Paediatric Respiratory Reviews 20 (August 2016): 1. http://dx.doi.org/10.1016/j.prrv.2016.06.002.

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33

Sermet-Gaudelus, Isabelle, Muriel Le Bourgeois, Catherine Pierre-Audigier, Catherine Offredo, Didier Guillemot, Sophie Halley, Chantal Akoua-Koffi, et al. "Mycobacterium abscessusand Children with Cystic Fibrosis." Emerging Infectious Diseases 9, no. 12 (December 2003): 1587–91. http://dx.doi.org/10.3201/eid0912.020774.

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34

Natochin, Yury V., Alla A. Kuznetsova, Anastasia V. Prokopenko, Gregorio P. Milani, Sebastiano A. G. Lava, and Anna S. Marina. "Osmoregulation in children with cystic fibrosis." European Journal of Pediatrics 179, no. 5 (January 2, 2020): 835–38. http://dx.doi.org/10.1007/s00431-019-03550-1.

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Balfour-Lynn, I. M., K. Malbon, J. F. Burman, and S. J. Davidson. "Thrombophilia in children with cystic fibrosis." Pediatric Pulmonology 39, no. 4 (2005): 306–10. http://dx.doi.org/10.1002/ppul.20181.

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Liabina, N. V., O. I. Simonova, I. V. Shirokova, E. L. Semikina, E. F. Mavrikidi, I. I. Kondrakhina, Yu V. Gorinova, and V. A. Kerimova. "Significance of fructosamine in the diagnosis of carbohydrate metabolism disorders in children with cystic fibrosis." Meditsinskiy sovet = Medical Council, no. 1 (March 3, 2022): 226–34. http://dx.doi.org/10.21518/2079-701x-2022-16-1-226-234.

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Introduction. Cystic fibrosis associated (related) diabetes mellitus (CFDM) is one of the most common severe complications of cystic fibrosis. Today, the issue of the goodness of a single measurement of fasting blood glucose, glycated hemoglobin and fructosamine to assess the degree of carbohydrate metabolism disorders in children with cystic fibrosis is a subject of debate. The gold standard for diagnosing carbohydrate metabolism disorders (impaired fasting glycemia, various pre-diabetic conditions, diabetes mellitus) is the oral glucose tolerance test. Data about the diagnostic value of fruc
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Diaconu, Ramona, Laura Bozomitu, Emil Anton, Paula Popovici, Carmen Anton, Daniel Timofte, Ciobica Alin, and Evelina Moraru. "Infectious and nutritional mechanisms in children with cystic fibrosis." Archives of Biological Sciences 67, no. 3 (2015): 1063–66. http://dx.doi.org/10.2298/abs140228070d.

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Cystic fibrosis is a polymorphic disease characterized by severe genetic dysfunctions. Besides the complex genetic background, most patients with cystic fibrosis also have increased susceptibility to infections and and their nutritional status is affected. Chronic pulmonary infection and gastrointestinal or nutritional abnormalities are characteristics of this disorder. Of our selected 56 subjects, 21.28% presented a pulmonary condition, and 28.57% digestive deregulation. We also observed that the infectious status in cystic fibrosis was dominated by respiratory infections (71.42%), and the ma
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Weber, Ronja, Nathan Perkins, Tobias Bruderer, Srdjan Micic, and Alexander Moeller. "Identification of Exhaled Metabolites in Children with Cystic Fibrosis." Metabolites 12, no. 10 (October 17, 2022): 980. http://dx.doi.org/10.3390/metabo12100980.

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The early detection of inflammation and infection is important to prevent irreversible lung damage in cystic fibrosis. Novel and non-invasive monitoring tools would be of high benefit for the quality of life of patients. Our group previously detected over 100 exhaled mass-to-charge (m/z) features, using on-line secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS), which distinguish children with cystic fibrosis from healthy controls. The aim of this study was to annotate as many m/z features as possible with putative chemical structures. Compound identification was p
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39

Werkhaven, Jay, and Lauren D. Holinger. "Bronchial Casts in Children." Annals of Otology, Rhinology & Laryngology 96, no. 1 (January 1987): 86–92. http://dx.doi.org/10.1177/000348948709600121.

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Bronchial casts were found in four children during a 2-year period at the Children's Memorial Hospital. These four children represent 0.2% of the 1,943 endoscopic cases during that time. Thirty other cases of bronchial casts have been reported previously in children 9 years of age or younger, only 12 of which were not associated with cystic fibrosis. Casts may be a complication of many diseases; cystic fibrosis, asthma, bronchitis, allergic bronchopulmonary aspergillosis, and bronchocentric granulomatosis are the most common. With the exception of cystic fibrosis, these diseases may all have a
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40

Strawhacker, MaryAnn Tapper, and Joyce Wellendorf. "Caring for Children With Cystic Fibrosis: A Collaborative Clinical and School Approach." Journal of School Nursing 20, no. 1 (February 2004): 5–15. http://dx.doi.org/10.1177/10598405040200010301.

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Earlier diagnosis and more effective treatments have improved both morbidity and mortality associated with cystic fibrosis, making regular school attendance a reality. School nurses have a unique opportunity to assist students with cystic fibrosis successfully manage their disease. Medical treatment for cystic fibrosis can be complex, leaving students and families in need of health consultation and support. The clinic and school nurse each brings a unique perspective to cystic fibrosis care management. Working to understanding perspectives across settings and looking for ways to collaborate th
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41

Leclercq‐Foucart, Jacqueline, Philippe Forget, FrançLoise Sodoyez‐Goffaux, and Ada Zappitelli. "Intestinal Permeability to [51Cr]EDTA in Children with Cystic Fibrosis." Journal of Pediatric Gastroenterology and Nutrition 5, no. 3 (May 1986): 384–87. http://dx.doi.org/10.1002/j.1536-4801.1986.tb09091.x.

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Summary: Intestinal permeability was investigated in 14 children with cystic fibrosis making use of [51Cr]EDTA as probe molecule. Ten normal young adults and 11 children served as controls. After oral administration of [51Cr]‐EDTA, 24 h urine was collected. Urinary radioactivity was calculated and results expressed as percentage of oral dose excreted in 24 h urine. Mean and SEM were as follows: 2.51 ± 0.21, 2.35 ± 0.24, and 13.19 ± 1.72 for control children, normal adults, and cystic fibrosis patients, respectively. The permeability differences between cystic fibrosis patients and either contr
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Mbonda, E., P. Forget, Z. Saye та J. Leclercq‐Foucart. "Usefulness of Random Fecal α1‐Antitrypsin and Chymotrypsin Determinations in Children". Journal of Pediatric Gastroenterology and Nutrition 8, № 1 (січень 1989): 85–88. http://dx.doi.org/10.1002/j.1536-4801.1989.tb09706.x.

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Random fecal chymotrypsin activity and fecal α1‐antitrypsin (FA‐1‐AT) concentrations were determined in 11 children with cystic fibrosis, 5 children with Crohn's disease, 9 children with chronic aspecific diarrhea, 85 children with acute gastroenteritis, and 54 control children. Cystic fibrosis patients showed only very low fecal chymotrypsin values that did not overlap with values obtained in patients with either acute or chronic diarrhea. When compared with our control group, a significant increase of FA‐1‐AT concentrations was found only in children with Crohn's disease. Normal values were
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Kondratyeva, E. I., A. I. Tlif, A. Yu Voronkova, E. L. Amelina, N. Yu Kashirskaya, S. A. Krasovsky, M. A. Starinova, and T. L. Kuraeva. "Characteristics of patients with cystic fibrosis-dependent diabetes mellitus in childhood according to the register of patients with cystic fibrosis of the Russian Federation in 2021." Diabetes mellitus 26, no. 5 (October 23, 2023): 418–26. http://dx.doi.org/10.14341/dm13064.

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BACKGROUND: In recent decades, the life expectancy of patients with CF has increased, which leads to an increase in the frequency of conditions associated with impaired carbohydrate metabolism.AIM: to analyze the impact of cystic fibrosis-associated diabetes mellitus (CFDM) in children and adolescents on the course of cystic fibrosis according to the 2021 register of patients with cystic fibrosis of the Russian Federation (RF).MATERIALS AND METHODS: the data of the register of patients with cystic fibrosis of the Russian Federation for 2021 were analyzed. The study included 122 patients with d
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Chaudhry, Sunil. "Cystic Fibrosis: Improving quality of life." Journal of Community Health Management 8, no. 2 (July 15, 2021): 91–96. http://dx.doi.org/10.18231/j.jchm.2021.021.

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Cystic Fibrosis (CF) or Mucoviscidosis is an inherited condition. In cystic fibrosis transmembrane conductance regulator (CFTR) protein does not functions properly i.e regulation of fluids and salts outside the cells. Cystic fibrosis affects exocrine glands eg., the mucus-secreting and sweat glands in the respiratory and digestive systems. The frequency of common mutation F508del (deletion of phenylalanine residue at position 508) in children is between 19% and 34%. The estimate frequency of CF as 1:10,000 to 1:40,000 in children. There is no cure for cystic fibrosis, but treatment can reduce
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Pizzignacco, Tainá Maues Peluci, Débora Falleiros de Mello, and Regina Aparecida Garcia de Lima. "Stigma and cystic fibrosis." Revista Latino-Americana de Enfermagem 18, no. 1 (February 2010): 139–42. http://dx.doi.org/10.1590/s0104-11692010000100021.

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Cystic Fibrosis (CF), also known as Mucoviscidosis, is a chronic disease of autosomal recessive origin and so far incurable. This analysis considers some characteristics of patients and family members that indicate it is a stigmatizing disease. The CF stigma’s impact on the lives of children and adolescents can affect treatment adherence, socialization, family relationships and the formation of their life histories, with direct consequences on their quality of life.
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Laskowska-Klita, T., and M. Chełchowska. "Antioxidant status in erythrocytes of cystic fibrosis children." Acta Biochimica Polonica 48, no. 1 (March 31, 2001): 283–85. http://dx.doi.org/10.18388/abp.2001_5137.

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Activities of superoxide dismutase, catalase and glutathione peroxidase in erythrocytes of cystic fibrosis children were studied in order to estimate the severity of their deficiency. Our results point to increased susceptibility of erythrocytes of cystic fibrosis subjects to oxidative injury and indicate that the antioxidant status of patients should be carefully monitored.
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King, Paul T., Lovisa Dousha, Nadeene Clarke, Jennifer Schaefer, Rosemary Carzino, Roleen Sharma, Ken L. Wan, et al. "Phagocyte extracellular traps in children with neutrophilic airway inflammation." ERJ Open Research 7, no. 2 (March 11, 2021): 00883–2020. http://dx.doi.org/10.1183/23120541.00883-2020.

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Childhood lung infection is often associated with prominent neutrophilic airway inflammation and excess production of proteases such as neutrophil elastase (NE). The mechanisms responsible for this inflammation are not well understood. One potentially relevant pathway is the production of extracellular traps by neutrophils (NETs) and macrophages (METs). The aim of this study was to measure NET and MET expression in children and the effect of deoxyribonculease (DNase) 1 and α1-antitrypsin (AAT) on this process.We studied 76 children (median age of 4.0 years) with cystic fibrosis or chronic coug
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Machura, Edyta, Katarzyna Ziora, Maria Szczepańska, Elżbieta Świętochowska, Franciszek Halkiewicz, Małgorzata Barć-Czarnecka, and Dariusz Ziora. "Serum levels of chemerin, omentin and vaspin in children with cystic fibrosis." Pediatric Endocrinology 16, no. 4 (2017): 255–62. http://dx.doi.org/10.18544/ep-01.16.04.1679.

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Huang, Ting, Caihong Li, and Daishun Liu. "Recurrent Cough and Expectoration for 10 Years: A Case Report." Global Pediatric Health 6 (January 2019): 2333794X1983372. http://dx.doi.org/10.1177/2333794x19833725.

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Rationale. Most cases of cystic fibrosis occur in Europe, with only a few occurring in Asia. Pulmonary cystic fibrosis is not a rare disease, but in children it is a potentially life-threatening condition. Children suffering from pulmonary cystic fibrosis rarely survive to adulthood, and responses to treatment are generally poor. The most common cause of cystic fibrosis is a genetic mutation on chromosome 7. Patient concerns. A 15-year-old boy with healthy parents suffered from a recurrent cough and expectoration for nearly 10 years. Six years previously, a definitive diagnosis of pulmonary cy
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Skachkova, T. S., E. V. Kniazeva, E. N. Goloveshkina, T. V. Tronza, E. I. Kondratyeva, A. Y. Voronkova, and V. G. Akimkin. "The Prevalence of Genetic Determinants of Antibiotic Resistance, which are of Particular Epidemiological Consequences, in the Microbiota of the Oropharyngeal Swabs in Patients with Cystic Fibrosis." Epidemiology and Vaccinal Prevention 22, no. 4 (September 20, 2023): 44–48. http://dx.doi.org/10.31631/2073-3046-2023-22-4-44-48.

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Relevance. Antibiotic resistance of microorganisms can contribute to the chronicity of the inflammatory process, lead to an increase in the cost of treating patients and make it difficult to eradicate the pathogen. Patients with cystic fibrosis constantly require medical supervision, regular visits to medical institutions, and therefore there is a high risk of infection with nosocomial antibiotic- resistant strains. In addition, the necessary intake of antibacterial drugs provides an advantage for the reproduction of resistant microorganisms.Aim. Comparison of the frequency of detection of ant
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