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Artykuły w czasopismach na temat „DEC Alpha”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Comerford, R. "How DEC developed Alpha." IEEE Spectrum 29, no. 7 (1992): 26–31. http://dx.doi.org/10.1109/6.144508.

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Hayakawa, J., T. Shiohara, N. Moriya, et al. "Identification of a novel population of CD8 alpha+ beta- bone marrow-derived dendritic epidermal cells. This unique population is subsequently outnumbered by thymus-independent expansion of the CD8 alpha+ beta+ dendritic epidermal cells." Journal of Immunology 151, no. 11 (1993): 5984–92. http://dx.doi.org/10.4049/jimmunol.151.11.5984.

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Abstract Maturation of some T cell populations has been suggested to occur in epithelial tissues. The CD8 molecule, which is expressed as heterodimers made of alpha/beta-chains on virtually all peripheral T cells, is preferentially expressed as homodimers made only of alpha-chains on a subset of CD8+ mouse gut intraepithelial lymphocytes, which arise from bone marrow (BM) precursors in a thymus-independent mechanism. This unique population of CD8 alpha+ beta- T cells, however, has not been identified in other lymphoid tissues in normal adult mice. Because our previous study demonstrated that r

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Shiohara, T., N. Moriya, J. Hayakawa, S. Itohara, and H. Ishikawa. "Resistance to cutaneous graft-vs.-host disease is not induced in T cell receptor delta gene-mutant mice." Journal of Experimental Medicine 183, no. 4 (1996): 1483–89. http://dx.doi.org/10.1084/jem.183.4.1483.

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The function of murine dendritic epidermal cells (dEC) remains largely speculative, probably because of the lack of a suitable in vivo model, although previous studies suggest that gamma/delta+ dEC may have originally evolved to serve as a self-protection mechanism(s). Our previous study demonstrated that the epidermis of mice that had spontaneously recovered from cutaneous graft-vs-host disease (GVHD) induced by local injection of CD4+ autoreactive T cells contained unexpectedly large numbers of dEC and became resistant to subsequent attempts to induce GVHD in a site-restricted manner, sugges

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Zadoff, A. D., T. Kobayashi, K. L. Brigham, and J. H. Newman. "Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep." Journal of Applied Physiology 60, no. 4 (1986): 1380–85. http://dx.doi.org/10.1152/jappl.1986.60.4.1380.

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Diethylcarbamazine (DEC) is an inhibitor of lipoxygenase, with protective effects in several experimental models of anaphylaxis and lung dysfunction. The hypothesis of this study was that DEC would alter the pulmonary response to endotoxin infusion, especially the prolonged pulmonary hypertension, leukopenia, hypoxemia, and high flow of protein-rich lung lymph. We prepared sheep for chronic measurements of hemodynamics and collection of lung lymph. In paired studies we gave six sheep endotoxin (0.5 micrograms/kg iv) either with or without DEC. DEC was given (80–100 mg/kg iv) over 30 min follow

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5

Havran, W. L., M. Poenie, R. E. Tigelaar, R. Y. Tsien, and J. P. Allison. "Phenotypic and functional analysis of gamma delta T cell receptor-positive murine dendritic epidermal clones." Journal of Immunology 142, no. 5 (1989): 1422–28. http://dx.doi.org/10.4049/jimmunol.142.5.1422.

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Abstract Thy-1+ dendritic cells isolated from the epidermis of normal mice (dEC)3 bear the gamma delta TCR associated with the CD3 complex. We have analyzed the effects of antibodies directed against the TCR complex, Ly-6C, and Thy-1, as well as pharmacologic agents which have been shown to activate T cells without engagement of the TCR complex, on levels of intracellular free calcium, activation of protein kinase C, cytolysis, IL-2R expression, and secretion of lymphokines by dEC clones. We have found that the dEC cells express a fully functional TCR complex which can function to transmit sig

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Iwu, Chidozie Declan, Nolonwabo Nontongana, Chinwe Juliana Iwu-Jaja, et al. "Spatial diarrheal disease risks and antibiogram diversity of diarrheagenic Escherichia coli in selected access points of the Buffalo River, South Africa." PLOS ONE 18, no. 8 (2023): e0288809. http://dx.doi.org/10.1371/journal.pone.0288809.

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Freshwater sources, often used for domestic and agricultural purposes in low- and middle-income countries are repositories of clinically significant bacterial pathogens. These pathogens are usually diversified in their antibiogram profiles posing public health threats. This study evaluated the spatial diarrhoeal disease risk and antibiogram diversity of diarrheagenic Escherichia coli (DEC) in four access points of the Buffalo River, Eastern Cape Province, South Africa using standard epidemiological, culture, and molecular methods. The diarrhoeal disease risk was characterised using the Monte C

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7

Soledad, Ortiz, M. Robles García Nelly, G. de Lucio Oscar, et al. "Hornos de cal de Monte Albán, México: estudio combinado de espectrometría de infrarrojo ATR-FTIR y arqueomagnetismo." Arqueologia Iberoamericana 48 (September 4, 2021): 30–43. https://doi.org/10.5281/zenodo.5418981.

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Los hornos de cal pueden proporcionar una importante información arqueológica sobre la producción de cal y su papel en la sociedad. Si bien se llevaron a cabo numerosas investigaciones arqueométricas en el área maya, aún no se dispone de tales estudios para el valle de Oaxaca. En este trabajo presentamos un análisis combinado de arqueomagnetismo y espectrometría infrarroja de dos hornos de cal recientemente descubiertos en Monte Albán. Se utilizó el método ATR-FTIR para estimar las temperaturas de calcinación.

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8

Gangadhar, Kiran, D. Santhosh, and I. Maurya. "The Role of Radiopathological Evaluation in Diagnosis of Beckwith-Wiedemann Syndrome." Nepalese Journal of Radiology 2, no. 2 (2013): 86–91. http://dx.doi.org/10.3126/njr.v2i2.7693.

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Beckwith-Wiedemann Syndrome (BWS), an overgrowth syndrome is associated with early development of embryonal tumours usually in the first four years of life. Hepatoblastoma is observed in 1% to 3% of persons with Beckwith-Wiedemann Syndrome or isolated hemihypertrophy(HH). We report a case of hepatoblastoma associated with both BWS and HH with raised serum alpha-feto protein levels and hypoglycaemia. Nepalese Journal of Radiology; Vol. 2; Issue 2; July-Dec. 2012; 86-91 DOI: http://dx.doi.org/10.3126/njr.v2i2.7693

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9

Owusu Sarfo, Jacob, Edward Wilson Ansah, Daniel Apaak, and Rafael Valdece Sousa Bastos. "Psychometric Properties of a Safety Culture Index among Mental Health Workers in Ghana." Archives of Psychiatry Research 59, no. 2 (2023): 277–84. http://dx.doi.org/10.20471/dec.2023.59.02.11.

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Safety culture among mental health workers is essential, especially in developing countries where workplace safety seems neglected. However, few studies have provided detailed psychometric analyses of convenient safety instruments with practical relevance for the healthcare industry in the Sub-Saharan African context. We sampled 574 (54.4 % females, 45.6 % males) mental health workers from three Specialist Psychiatric Teaching Hospitals in Ghana. Initially, we collected data using adapted items from Edkins and Coakes’ 25-item Airline Safety Culture Index (ASCI). Consequently, we conducted a Co

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Nadeem, Aamer, Noreen Anwar, Naveed Ahmed, Yasser Saeed Khan, Irum Rashid, and Mujahid Zulfiqar Ali. "ROLE OF ALPHA BLOCKER IN URETERORENOSCOPY." PAFMJ 71, no. 6 (2021): 2033–36. http://dx.doi.org/10.51253/pafmj.v6i6.5647.

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Objective: To determine the efficacy of alpha blockers in successful management of lower and mid ureteral stones by ureterorenoscopy. Study Design: Comparative prospective study. Place and Duration of Study: Department of Urology, Combined Military Hospital Quetta Pakistan, from Jul 2018 to Dec 2019. Methodology: Total of 150 patients having mid and lower ureteric calculi requiring ureterorenoscopy were divided into two groups. Group A included patients without pre-treatment with alpha blocker was administered before they were subjected to ureterorenoscopy. Study group B incl

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11

Sururin, Fahma Wardah, and Nida An Khafiyya. "Prediction Prediction of the Insecticidal Potency of Biduri Plants (Calotropis gigantea) using the PASS online web resource." Life Science and Biotechnology 2, no. 1 (2024): 13. http://dx.doi.org/10.19184/lsb.v2i1.47444.

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Calotropis gigantea, a wild plant thriving in arid environments, has been traditionally used for medicinal purposes by communities near Baluran National Park (BNP). The latex of C. gigantea is used as a crab poison due to its ability to cause fatal damage and separation of body parts, possibly related to chitin disruption in insects. This study explores the potential insecticidal properties of secondary metabolites in C. gigantea using Prediction of Activity Spectra for Substance (PASS) Online. Out of 68 identified secondary metabolites, six show significant insecticidal potential, namely Prof

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12

Heil, K. M., A. M. Wood, J. Penn-Barwell, A. C. M. Keenan, and S. McKie. "Femoral Acetabular Impingement: the sex- and agelinked distribution of alpha angles in 146 patients of service age without pre-existing osteoarthritic or other hip pathology." Journal of The Royal Naval Medical Service 99, no. 3 (2013): 111–14. http://dx.doi.org/10.1136/jrnms-99-111.

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AbstractThe use of the alpha angle to help the diagnosis of Femoral Acetabular Impingement (FAI) is common. However, there is currently no standard value available across an asymptomatic pre-arthritic population. We present the first large cohort of Computerised Tomography (CT) based alpha angles in patients with no history of hip pathology, including intra– and interobserver validation. We carried out a retrospective analysis of 73 consecutive individuals (146 hip joints) with ages ranging from 18 to 39 years. The age range 18–39 represents 82.4% of those currently serving in the UK Armed For

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13

PIET, Dennis Patrick, Romano Vincenzo Antonio ORRU, Louis Henri Dieudonne JENNISKENS, et al. "Synthesis of (1.ALPHA.,7.ALPHA.,8.BETA.-(.+-.)-8-Methyl-2-methylenebicyclo(5.3.0)dec-5-en-8-ol. Structure Revision of Natural Dictamnol." CHEMICAL & PHARMACEUTICAL BULLETIN 44, no. 7 (1996): 1400–1403. http://dx.doi.org/10.1248/cpb.44.1400.

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Konarev, Petr V., Maxim V. Petoukhov, Vladimir V. Volkov, and Dmitri I. Svergun. "ATSAS2.1, a program package for small-angle scattering data analysis." Journal of Applied Crystallography 39, no. 2 (2006): 277–86. http://dx.doi.org/10.1107/s0021889806004699.

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The program packageATSAS2.1 for small-angle X-ray and neutron scattering data analysis is presented. The programs included in the package cover the major processing and interpretation steps from primary data reduction to three-dimensional modelling. This system is primarily oriented towards the analysis of biological macromolecules, but could also be used for non-biological isotropic and partially ordered objects (nanoparticle systems, colloidal solutions, polymers in solution and bulk). Recent developments in the programs included inATSAS2.1 are highlighted. The main programs run on multiple

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15

Urooj, Uzma, Sumaira Khan, Shakeela Parveen, and Sajid Ali Shah. "Effectiveness of 17-Alpha-Hydroxyprogesterone in the Prevention of Preterm Labour." Pakistan Armed Forces Medical Journal 73, no. 1 (2023): 256–59. http://dx.doi.org/10.51253/pafmj.v73i1.5314.

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Objective: To compare the effectiveness of 17-Alpha- Hydroxyprogesterone in preventing preterm labour. Study Design: Prospective longitudinal study. Place and Duration of Study: Department of Obstetrics and Gynecology, Combined Military Hospital, Sakardu Pakistan, from Jun to Dec 2019. Methodology: A total of 208 patients (104 in each group) were recruited in this study. Group-A 17-alpha-hydroxyprogesterone (250mg) intramuscular injection was given weekly from 20-36 weeks of gestation or delivery, whichever occurred first. GroupB (Control Group) received no treatment except r

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Mazloum, Syeda Fouzia, Amina Nadeem, Sidra Shauqat, and Nadia Latif. "Association of Serum Apelin levels with Peripheral Neuropathy in Type-2 Diabetes Mellitus." Pakistan Armed Forces Medical Journal 72, no. 5 (2022): 1808–11. http://dx.doi.org/10.51253/pafmj.v72i5.8433.

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Objectives: To determine serum levels of Apelin in healthy individuals, type-2 diabetic patients and diabetic peripheral neuropathy patients (DPN) and to find the correlation with serum Apelin levels and serum fasting blood glucose, glycosylated hemoglobin. Study Design: Cross-sectional analytical study. Place and Duration of Study: Physiology Department and Centre for Research in Experimental and Analytical Medicine (CREAM) lab of the Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan, from Jan to Dec 2021. Methodology: A total of 90 indi

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Yamatani, Kotoko, Kaori Saito, Abhishek Maiti, et al. "Decitabine-Venetoclax Treatment Reactivates Endogenous Retrovirus RNA Signaling in AML Cells and Induces T Cell Activation." Blood 144, Supplement 1 (2024): 1389. https://doi.org/10.1182/blood-2024-202722.

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The combination of hypomethylating agents such as decitabine (DEC) with venetoclax (VEN) has become the standard of care for AML patients who are not suitable for intensive chemotherapy. In this study, we investigated the reactivation of endogenous retroviruses (ERVs) in AML patients treated with DEC-VEN, activation of interferon (IFN) responses and cytotoxic T cells in the bone marrow (BM) microenvironment. Bulk and single-cell (sc) RNA-seq analyses of primary samples from AML patients participating in the prospective DEC-VEN clinical trial (NCT03404193) were performed to assess the effect of

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18

Liu, Qi Mei, та Wan Xi Peng. "80°С-Based TD-GC/MS Analysis of Chemical Components from Branches of Cinnamomum camphora". Key Engineering Materials 480-481 (червень 2011): 466–71. http://dx.doi.org/10.4028/www.scientific.net/kem.480-481.466.

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The analytical result by 80°С-based TD-GC/MS showed that 65 peaks were obtained from the helium volatiles from the fresh branches of Cinnamomum camphora and 60 chemical compounds were identified. The results showed that the main components were as: 1,3-Benzodioxole, 5-(2-propenyl)- (12.629%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (10.302%), 3-Cyclohexene-1-methanol, .alpha.,.alpha.4-trimethyl- (9.084%), Bicyclo[2.2.1] heptan-2-one, 1,7,7-trimethyl-, (1R)- (7.406%), Nerolidol (6.695%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3-pentenyl)-, (1S

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19

Guo, Yuyang, Xiao Wu, Hidekazu Ikezaki, and Kiyoshi Toko. "Development of a Bitterness Sensor Using Partially Dissociated Amine Compounds." Sensors 24, no. 17 (2024): 5553. http://dx.doi.org/10.3390/s24175553.

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This study focused on developing an advanced bitterness sensor designed to minimize interference from common anions such as nitrate (NO3−) and iodide (I−) by incorporating partially dissociated amine compounds into the sensor membrane. The conventional bitter sensor (C00) uses fully dissociated quaternary ammonium salt tetradecyl ammonium bromide (TDAB), which typically exhibits high responses to these anions, leading to inaccurate bitterness assessments. To address this issue, we explored the use of three partially dissociated amines—oleylamine (OAm), dioctadecylamine (DODA), and tridodecylam

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Javed, Ambreen, Gulshan Ara Trali, Hassan Burair Abbas, and Alia Sadiq. "IN SILICO CHARACTERIZATION OF HUMAN INTERFERON ALPHA/BETA RECEPTOR 2 (ISOFORM A, B AND C) PROTEIN." PAFMJ 71, no. 6 (2021): 2091–94. http://dx.doi.org/10.51253/pafmj.v71i6.6571.

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Objective: To predict the tertiary structure of human interferon alpha/beta receptor 2 protein. Study Design: Structure prediction by using bio informatics tools. Place and Duration of Study: Department of Biochemistry, Swat Medical College (STMC), Saidu Shareef, Swat, Pakistan, from Aug 2019 to Dec 2019. Methodology: All protein sequences of human interferon alpha/beta receptor 2 (isoforma, b and c) (IFNAR-2) were retrieved through the BLAST search (The Basic Local Alignment Search Tool) from available databases ‘NCBI’ (National Centre for Biotechnology Information) and ‘Uni

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Chumakova, S. P., O. I. Urazova, V. M. Shipulin, et al. "Production of angiogenesis mediators and the structure of the vascular wall in the heart in ischemic cardiomyopathy." Acta Biomedica Scientifica 8, no. 6 (2024): 81–90. http://dx.doi.org/10.29413/abs.2023-8.6.7.

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Background. In the pathogenesis of ischemic cardiomyopathy (ICMP), angiopoiesis remains unexplored.The aim. To describe the vasculature of the heart and the imbalance of angiogenesis mediators in the coronary circulation in association with the number of endothelial progenitor cells (EPC) and desquamated endothelial cells (DEC) in the blood of patients with coronary heart disease (CHD), suffering and not suffering from ICMP.Methods. Fifty-two patients with CHD (30 patients with ICMP, 22 patients without ICMP), 15 healthy donors were examined. The content of EPC (CD14+CD34+VEGFR2+) in the blood

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Raj, Yashaswi, and Rajat Sharma. "Snake Game Using Hand Recognition System." International Journal for Research in Applied Science and Engineering Technology 10, no. 5 (2022): 1289–92. http://dx.doi.org/10.22214/ijraset.2022.42523.

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Abstract: This paper presents engineering and execution nuances of a hand's movement furthermore motion acknowledgment framework which has been created at Meerut Institute of Engineering and Technology. The framework utilizes live 15-piece shading video from an arranged camera, runs in genuine time (On a DEC Alpha, 25 edges per second), and adapts well to foundation mess. Following is accomplished utilizing the 2D deformable Active Shape Models (savvy snakes), what's more a genetic calculation is utilized to play out an underlying worldwide picture search. The Point Distribution Model, which w

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Yıldız, Yıldız Mutlu. "High School Students’ Music Listening Habits and Attitudes towards Intangible Cultural Heritage Elements." Shanlax International Journal of Education 11, S1-Dec (2022): 137–49. http://dx.doi.org/10.34293/education.v11is1-dec.5926.

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In this study, it was aimed to reveal the relationship between high school students’ music listening habits and their attitudes towards intangible cultural heritage elements. The research sample consists of 353 students studying at Isparta Süleyman Demirel Science High School. Research data were collected with a structured questionnaire. In the first part of the structured questionnaire consisting of three parts, there are questions to determine gender and grade, in the second part there are questions to determine the music listening habits of the students, and in the last part there is the In

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Lübbert, Michael, Claudia Schmoor, Olga Grishina, et al. "Decider-2: Prospective Randomized Multicenter Phase III Trial of Decitabine and Venetoclax Administered in Combination with All- Trans Retinoic Acid (ATRA) or Placebo in Patients with Acute Myeloid Leukemia Who Are Ineligible for Induction Chemotherapy." Blood 142, Supplement 1 (2023): 1495. http://dx.doi.org/10.1182/blood-2023-181871.

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Background and Significance DNA-hypomethylating agent (HMA) based therapy is the treatment backbone for older, medically non-fit AML/MDS pts, and studies have been performed with multiple combination partners over the last years (reviewed by Stomper et al., Leukemia 2021). Recently, the combination of azacitidine or decitabine (DEC) with venetoclax (VEN) has become the novel standard for many of these pts. Based on preclinical evidence of priming of AML cells to all- trans retinoic acid (ATRA) by DEC, we have conducted a randomized phase II trial in 200 elderly and medically non-fit AML pts on

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Umar, Saba, Sohail Sabir, Ashfaq Altaf, et al. "Efficacy of Alpha Keto-Analogues in The Management of Chronic Kidney Disease." Pakistan Armed Forces Medical Journal 72, no. 1 (2022): 292–95. http://dx.doi.org/10.51253/pafmj.v72i1.6154.

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Objective: To determine the efficacy of alpha keto-analogues in the management of chronic kidney disease at a tertiary care hospital. Study Design: Quasi-experimental study. Place and Duration of Study: Nephrology Department, Armed Forces Institute of Urology, Rawalpindi from Jul to Dec 2020. Methodology: A total of 300 patients of chronic kidney disease stage 3 and 4, not dependent on hemodialysis were included in the study. They were divided into two groups with matched age, gender and duration of chronic kidney disease. Group-I received the routine treatment of chronic kid

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Ravandi, Farhad, Ellen K. Ritchie, Hamid Sayar, et al. "VALOR, an adaptive design, pivotal phase III trial of vosaroxin or placebo in combination with cytarabine in first relapsed or refractory acute myeloid leukemia." Journal of Clinical Oncology 30, no. 15_suppl (2012): TPS6637. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.tps6637.

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TPS6637 Background: The promising phase 2 activity/tolerability profile of vosaroxin with cytarabine in first relapsed or refractory AML (N=69) with median overall survival (OS) 7.1 mo, combined CR 28% (CR 25%), median LFS 25 mo and 30-day all‑cause mortality 3%, supported phase 3 trial. VALOR (NCT01191801), a phase 3, randomized, controlled, double-blind trial, evaluates vosaroxin and cytarabine versus placebo and cytarabine in patients with first relapsed or refractory AML and incorporates an adaptive design. Primary objective is OS; secondary/tertiary objectives include CR rates, safety, EF

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Bohren, Meghan A., Charbel Abi Saad, Charles Kabore, et al. "Women’s experiences of and satisfaction with childbirth: Development and validation of a measurement scale for low- and middle-income countries." PLOS One 20, no. 5 (2025): e0322132. https://doi.org/10.1371/journal.pone.0322132.

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Background Measuring person-centered maternity care outcomes typically consists of two types of measures: experiences of care and satisfaction with care. There are limited validated measurement tools for these measures, particularly in low- and middle-income countries (LMICs). The QUALI-DEC study aims to improve decision-making around caesarean section. We describe development of the QUALI-DEC Study Birth Experience and Satisfaction (QD-BES) scale, and scale validation in Argentina, Burkina Faso, Thailand, and Viet Nam. Methods We used a three-phase scale development and validation approach: 1

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Olbryś, Joanna. "Obciążenie estymatora współczynnika alfa Jensena a interpretacje parametrów klasycznych modeli market-timing." Przegląd Statystyczny. Statistical Review 2011, no. 1-2 (2011): 42–59. http://dx.doi.org/10.59139/ps.2011.01-02.3.

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Jensen’s alpha coefficient was introduced in 1968 as a measure of the manager’s ability to forecast future security prices (M.C. Jensen, The performance of mutual funds in the period 1945 – 1964, „The Journal of Finance”). The paper concluded that the performance measure ? may be positive for two reasons: 1) extra returns earned on the portfolio due to the manager’s ability and/or 2) a positive â estimator bias. In 1977, D.Grant (Portfolio performance and the „cost” of timing decisions, „The Journal of Finance”) stated that Jensen’s original work contained a mathematical error and a conceptual

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Carlos, TM, BR Schwartz, NL Kovach, et al. "Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells [published erratum appears in Blood 1990 Dec 1;76(11):2420]." Blood 76, no. 5 (1990): 965–70. http://dx.doi.org/10.1182/blood.v76.5.965.965.

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Abstract The expression and function of a new cytokine-induced endothelial cell adhesion protein, vascular cell adhesion molecule-1 (VCAM-1), was characterized in vitro by using a monoclonal antibody, MoAb 4B9, which recognizes a functional epitope on this protein. As determined by enzyme-linked immunosorbent assay and radioimmunoprecipitation of metabolically labeled cells, VCAM-1 was minimally expressed on unstimulated human umbilical vein endothelium (HUVE), but was rapidly induced by recombinant human tumor necrosis factor-alpha (rhTNF-alpha), rh interleukin-1, and lipopolysaccharide. In c

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Carlos, TM, BR Schwartz, NL Kovach, et al. "Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells [published erratum appears in Blood 1990 Dec 1;76(11):2420]." Blood 76, no. 5 (1990): 965–70. http://dx.doi.org/10.1182/blood.v76.5.965.bloodjournal765965.

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The expression and function of a new cytokine-induced endothelial cell adhesion protein, vascular cell adhesion molecule-1 (VCAM-1), was characterized in vitro by using a monoclonal antibody, MoAb 4B9, which recognizes a functional epitope on this protein. As determined by enzyme-linked immunosorbent assay and radioimmunoprecipitation of metabolically labeled cells, VCAM-1 was minimally expressed on unstimulated human umbilical vein endothelium (HUVE), but was rapidly induced by recombinant human tumor necrosis factor-alpha (rhTNF-alpha), rh interleukin-1, and lipopolysaccharide. In contrast t

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Klemeyer, Horst Jan, and Leo A. Paquette. "Consequences of .alpha.-Bromo Substitution on the Course of Allylmetal Additions to 1-Oxaspiro[4.5]dec-7-en-6-one." Journal of Organic Chemistry 59, no. 25 (1994): 7924–27. http://dx.doi.org/10.1021/jo00104a062.

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Akbar Waheed, Malik Sikandar Mehmood, Shabana Ali, Arooj Shahid, and Uzma Naeem. "Evaluation and Comparison of the Preventive Role of Nebivolol and Alpha- Tocopherol in Testosterone-Induced Benign Prostatic Hyperplasia in Rats." Pakistan Armed Forces Medical Journal 74, no. 2 (2024): 535–39. http://dx.doi.org/10.51253/pafmj.v74i2.11039.

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Objective: To evaluate and compare the preventive role of Nebivolol and Alpha Tocopherol on testosterone-induced benign prostatic hyperplasia in rats. Study Design: Laboratory-based experimental study Place and Duration of Study: Department of Pharmacology and Pathology, Army Medical College, Rawalpindi, in collaboration with National Institute of Health (NIH), Islamabad Pakistan, from Dec 2021 to Jun 2022. Methodology: One hundred fifty healthy male Sprague-Dawley rats were procured from the NIH, Islamabad. They were placed into five groups, each with 30 rats. Results: Out of a total 150 samp

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Abaid, Mehwish, Khadija Qamar, Zubia Iftikhar, Sumyyia Bashir, Farhan Akhtar, and Maria Aslam. "Amelioration of Carboplatin-Induced Changes in Rat Renal Cortical Tubulesby Alpha-Tocopherol." Pakistan Armed Forces Medical Journal 72, no. 4 (2022): 1359–63. http://dx.doi.org/10.51253/pafmj.v72i4.8867.

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Objective: To determine the effects of carboplatin and alpha-tocopherol co-administration on gross kidney features and renal cortical tubules of carboplatin-treated rats. Study Design: Laboratory-based experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College/National University of Medical Sciences Rawalpindi Pakistan, in collaboration with the National Institute of Health (NIH) and Pathology Lab Pak Emirates Rawalpindi Pakistan, from Jan to Dec, 2021. Methodology: Thirty adults "Sprague-Dawley rats" of both genders were used and were divide

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Amardeep, Gupta*. "COMPARISON OF IPIC WITH CURRENT TRENDS OF SERVERS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 7 (2017): 427–29. https://doi.org/10.5281/zenodo.828799.

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Today we can fit the extensive software needed to drive a World Wide Web server into a computer the size of a box of matches. A Stanford University professor has created what is believed to be the world's smallest Web server, the size of matchbox, which was designed to ultimately be worn by a use

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Bird, D. M. "Quantitative CBED: an overview." Proceedings, annual meeting, Electron Microscopy Society of America 53 (August 13, 1995): 130–31. http://dx.doi.org/10.1017/s0424820100137021.

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In this abstract I will focus on one particular topic which has widespread relevance in the quantitative analysis of CBED; namely the role of computer simulations of CBED patterns. The basic point is that with modern, high-powered workstations we can perform highly accurate and detailed simulations of all types of CBED patterns from crystals in a relatively short amount of time. Most CBED simulations are based on diagonalisation of the many-beam equations, and, for example, on a DEC Alpha workstation one can perform this calculation on a 150 × 150 matrix (sufficient for a highly accurate simul

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Zhang, Zhaoxue, Xinye Liu, Mengfei Tao, et al. "Taxonomy, Phylogeny, Divergence Time Estimation, and Biogeography of the Family Pseudoplagiostomataceae (Ascomycota, Diaporthales)." Journal of Fungi 9, no. 1 (2023): 82. http://dx.doi.org/10.3390/jof9010082.

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Species of Pseudoplagiostomataceae were mainly introduced as endophytes, plant pathogens, or saprobes from various hosts. Based on multi-locus phylogenies from the internal transcribed spacers (ITS), the large subunit of nuclear ribosomal RNA gene (LSU), partial DNA-directed RNA polymerase II subunit two gene (rpb2), the partial translation elongation factor 1-alpha gene (tef1α), and the partial beta-tubulin gene (tub2), in conjunction with morphological characteristics, we describe three new species, viz. Pseudoplagiostoma alsophilae sp. nov., P. bambusae sp. nov., and P. machili sp. nov. Mol

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McQueen, Sarah, Adam Ware, Heather Cunliffe, and Fiona McDonald. "Abstract P2-16-07: Overexpression of the alpha subunit of the epithelial sodium channel in MDAMB231 breast cancer cells reduces cell migration and proliferation." Cancer Research 83, no. 5_Supplement (2023): P2–16–07—P2–16–07. http://dx.doi.org/10.1158/1538-7445.sabcs22-p2-16-07.

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Abstract Breast cancer is the most common cancer diagnosed in women worldwide and leads to 600,000+ deaths annually. The vast majority of breast cancer-related deaths are attributed to metastasis from the primary site in the breast to visceral organs or the brain. Therefore, understanding how these cells achieve metastasis is vital. Ion channels, such as the epithelial sodium channel (ENaC), are emerging as new targets for cancer research due to their role in regulating cell functions such as the process that allows cancer cells to undergo phenotypic changes necessary for metastasis. Ion chann

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Kogo, Hideki, and Hidemi Takahashi. "Sa1662 - Suppression of Murine Tumor Growing Through Cd8 + Ctls via Activated Dec-205 + Dendritic Cells by Sequential Administration of Alpha-Galactosylceramide in Vivo." Gastroenterology 154, no. 6 (2018): S—345. http://dx.doi.org/10.1016/s0016-5085(18)31486-0.

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Bevilacqua, A., D. Bollini, R. Campanini, N. Lanconelli, and M. Galli. "A New Approach to Image Reconstruction in Positron Emission Tomography Using Artificial Neural Networks." International Journal of Modern Physics C 09, no. 01 (1998): 71–85. http://dx.doi.org/10.1142/s0129183198000078.

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This study investigates the possibility of using an Artificial Neural Network (ANN) for reconstructing Positron Emission Tomography (PET) images. The network is trained with simulated data which include physical effects such as attenuation and scattering. Once the training ends, the weights of the network are held constant. The network is able to reconstruct every type of source distribution contained inside the area mapped during the learning. The reconstruction of a simulated brain phantom in a noiseless case shows an improvement if compared with Filtered Back-Projection reconstruction (FBP)

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Shafiq Ur Rahman, Rahman Syed, Ameer Afzal Khan, Maria Qadri, Muhammad ibrahim, and Bilal Iqbal. "Cryptogenic Decompensated Chronic Liver Disease Complicated By Hepatocellular Carcinoma: A Challenging Case Report And Comprehensive Literature Review." Journal of Bacha Khan Medical College 6, no. 01 (2025): 87–91. https://doi.org/10.69830/jbkmc.v6i1.199.

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Introduction We present a case of a 70-year-old non-alcoholic non-circumcised patient with a past history of chronic liver disease CLD, complicated by portal vein thrombosis. He reported gradual abdominal distension and pain in right hypochondrium with inappetence. He had no history of hematemesis, temperature, and pale bowel movement or drug abuse. Physically, the patient was icteric, had bilateral pitting edema, hepatomegaly as well as splenomegaly. Laboratory examinations showed increased levels of serum bilirubin, transaminases, creatinine, and urea, hypoalbuminemia, and extended prothromb

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Shafiq, Sameera, Faiza Kiran, and Maryam Batool. "Development and Validation of Body Dysmorphic Disorder Scale for Screening General Population." Pakistan Armed Forces Medical Journal 73, no. 3 (2023): 771–75. http://dx.doi.org/10.51253/pafmj.v73i3.8521.

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Objective: To develop a reliable and valid Urdu indigenous Body Dysmorphic Disorder Scale (BDDS) for the Pakistani community. Study Design: Cross-sectional study Place and Duration of Study: Department of Psychology, University of Gujrat, Gujrat Pakistan, from Jun to Dec 2020. Methodology: Based on the literature review, DSM-V criteria and semi-structured interviews conducted with psychologists clinical psychologists, and psychiatrists, an item pool of 78 items was generated for BDDS. A panel of five experts evaluated these items for content and revised them based on judgemen

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Bongers, Quinn, Ken Kunisaki, and Muna Irfan. "0546 An Informatics Approach to Assessing Quality of Care Metrics for Restless Legs Syndrome/Willis-Ekbom Disease." Sleep 45, Supplement_1 (2022): A241. http://dx.doi.org/10.1093/sleep/zsac079.543.

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Abstract Introduction Management of restless legs syndrome (RLS, aka Willis-Ekbom Disease) with dopaminergic agents is often complicated by development of augmentation. Clinical practice guidelines and stepwise algorithms suggest that prior to prescribing dopaminergic agents, clinicians should assess iron stores and consider alpha-2-delta agents (e.g. gabapentin). We developed an informatics approach to assess quality of care metrics for RLS management. Methods We used Veterans Affairs (VA) electronic health record data to identify a cohort of patients at a single tertiary care academic VA fac

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Cushman, Kent E., Muhammad Maqbool, Hemant Lata, Ebru Bedir, Ikhlas A. Khan, and Rita M. Moraes. "Podophyllotoxin Content and Yield of American Mayapple Leaves in Sun and Shade." HortScience 40, no. 1 (2005): 60–63. http://dx.doi.org/10.21273/hortsci.40.1.60.

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Four levels of shade (0%, 30%, 55%, and 80%) were used to determine their effect on growth and lignan content of american mayapple (Podophyllum peltatum L.). Mayapple rhizomes were harvested from the wild and transplanted into plant beds on 20 Dec. 2001 using a randomized complete block design with four blocks. Growth and lignan content were recorded during spring of 2002 and 2003. Leaf samples were analyzed for the following lignans: podophyllotoxin, alpha-peltatin, and beta-peltatin. Increasing levels of shade increased shoot longevity, leaf area per plant (cm2/plant), and shoot height. Shad

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Kato, Tomoyuki, Masatsugu Iwamura, Tetsuo Fujita, et al. "Phase II clinical trial of low-dose interleukin-2, interferon-alpha, and low-dose tegafur uracil therapy for advanced renal cell cancer." Journal of Clinical Oncology 33, no. 7_suppl (2015): 508. http://dx.doi.org/10.1200/jco.2015.33.7_suppl.508.

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508 Background: The objective of this trial was to evaluate the efficacy and safety of immunochemotherapy with very low-dose interleukin-2, interferon-alpha and tegafur uracil (IAT therapy) in treatment naïve metastatic renal cell carcinoma (RCC) patients with pulmonary metastasis only. Methods: Previously untreated metastatic renal cell cancer patients only with pulmonary metastasis were enrolled in this multicenter, open-label, single arm, phase II trial. Eligibility criteria included ECOG performance status (PS) 0-2, low or intermediate risk per MSKCC score, and adequate organ function. The

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Pratiwi, Rina Hidayati, Endang Sulistyaniningsih, and Jumadi Jepri. "In Silico Studies of Bioactive Compounds from Pseudomonas azotoformans UICC B-91 in Inhibiting Candida albicans." Jurnal Biodjati 9, no. 1 (2024): 26–40. http://dx.doi.org/10.15575/biodjati.v9i1.32147.

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Futoamide, Gentialutine, Gentiabetine, 1-[(2E,4E)-2,4-dec- adienoyl] pyrrolidine, Lycopodine, Dihydro-lycopodine are bioactive compounds that can be obtained Pseudomonas azotoformans UICC B-91. Previous research results indicate that P. azotoformans extract- ed with dichloromethane, chloroform, and ethyl acetate have antican- didal activity against Candida albicans ATCC 10231. C. albicans is considered to become an opportunistic pathogen and well-known as the main cause of candidiasis. This study aims to determine the mech- anism of inhibition of bioactive compounds from P. azotoformans UICC B

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Chun, Brie, Shaun Goodyear, Travis Rice-Stitt, et al. "Abstract P1-04-02: Gut microbiome diversity correlates with tumor PD-L1 status in metastatic triple negative breast cancer (mTNBC): correlative analysis of gut microbiome and tumoral biomarkers." Cancer Research 83, no. 5_Supplement (2023): P1–04–02—P1–04–02. http://dx.doi.org/10.1158/1538-7445.sabcs22-p1-04-02.

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Abstract Background: Greater gut microbiome diversity is observed in patients with a clinical response to immune checkpoint inhibitor (ICI) therapy in solid tumors and in preclinical models targeting the gut microbiome is a promising strategy to improve ICI efficacy. The investigation of the immunomodulatory effects of the gut microbiome and tumor biology is in its infancy and whether interindividual microbiome variations correlate with tumor biology in breast cancer is unknown. Here we report a correlative analysis of gut microbiome diversity with tumor biomarkers: PD-L1, tumor immune cell de

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Roy, S., S. Russo, G. Black, et al. "Upregulation of thymidine phosphorylase (TP) by radiation (XRT): Phase II study of capecitabine (CAP) with XRT in pts with locally advanced (LA) pancreatic cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 14001. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.14001.

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14001 Background: Preliminary studies have shown that XRT unregulates TP, the main enzyme responsible for activity of CAP. The objectives of this phase II study were to further evaluate effect of XRT on TP, DPD, and TNF-alpha as well as response and efficacy of CAP with concurrent XRT in pts with LA pancreatic cancer. Methods: Pts received 50.4 Gy XRT with CAP at 1600 mg/m2 M-F × 6 wks determined from our phase I study (JCO, Dec 2005). Following CAP-XRT, stable and responding pts on CT scan were treated with CAP 2000mg/m2 × 14 days q 3 wks till progression. Restaging was performed every 9 wks.

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Chopra, Karishma A., and Ajaz Banka. "Management of Pheochromocytoma in a Patient With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement." Journal of the Endocrine Society 5, Supplement_1 (2021): A141—A142. http://dx.doi.org/10.1210/jendso/bvab048.286.

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Abstract Background: There are few guidelines for the management of patients with both significant cardiac valvular disease and pheochromocytoma. Resection of pheochromocytoma is challenging for surgeons and anesthesiologists due to the potential for sudden releases of catecholamines causing significant hemodynamic effects. The cornerstone of perioperative management of pheochromocytoma involves alpha blockade to prevent the potential for hypertensive crisis from unopposed alpha-adrenergic vasoconstriction. Achieving adequate adrenergic blockade is challenging in patients with aortic stenosis

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Tu, Cheng, and Glenn A. Berchtold. "Total synthesis of (.+-.)-(1.beta.,6.alpha.,9.beta.,10.alpha.)-9-chloro-10-hydroxy-8-(methoxycarbonyl)-4-methylene-2,5-dioxabicyclo[4.4.0]dec-7-en-3-one, the first chloride-containing chorismate metabolite from fungi." Journal of Organic Chemistry 58, no. 24 (1993): 6915–16. http://dx.doi.org/10.1021/jo00076a069.

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Yoifoi, Ponlawat, and Wichean Kriwattanawong. "Galaxy evolution in different environments along redshift within the local universe z < 0.8." Journal of Physics: Conference Series 2145, no. 1 (2021): 012002. http://dx.doi.org/10.1088/1742-6596/2145/1/012002.

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Abstract This study presents the evolution of the galaxies in different matter density along redshift within the local universe. A sample of 702,352 galaxies was collected from the Sloan Digital Sky Survey (SDSS). Under the limitation of the spectroscopic data, the appropriate photometric redshift was used to represent the spectroscopic redshift in the range of 0.0 ≤ z ≤ 0.8. Number density of galaxies, galaxy’s colors, and star formation activities are considered to describe the evolution of galaxies. In summary, the number density is not clearly different although the Dec and RA of the sky a

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