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1

Gjøra, Linda, Bjørn Heine Strand, Sverre Bergh, et al. "Prevalence and Determinants of Diagnosed Dementia: A Registry Linkage Study Linking Diagnosis of Dementia in the Population-Based HUNT Study to Registry Diagnosis of Dementia in Primary Care and Hospitals in Norway." Journal of Alzheimer's Disease 99, no. 1 (2024): 363–75. http://dx.doi.org/10.3233/jad-240037.

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Background: A timely diagnosis of dementia can be beneficial for providing good support, treatment, and care, but the diagnostic rate remains unknown and is probably low. Objective: To determine the dementia diagnostic rate and to describe factors associated with diagnosed dementia. Methods: This registry linkage study linked information on research-based study diagnoses of all-cause dementia and subtypes of dementias, Alzheimer’s disease, and related dementias, in 1,525 participants from a cross-sectional population-based study (HUNT4 70+) to dementia registry diagnoses in both primary-care a
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Chahyani, Wiwit Ida, and Murni Sri Hastuti. "Mixed Dementia: Tinjauan Diagnosis dan Tatalaksana." Muhammadiyah Journal of Geriatric 1, no. 2 (2021): 46. http://dx.doi.org/10.24853/mujg.1.2.46-51.

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Latar Belakang: Prevalensi demensia saat ini semakin meningkat, mengenai usia diatas 65 tahun dan risikonya meningkat 2 kali setiap penambahan usia 5 tahun. Salah satu bentuk demensia adalah mixed dementia. Diagnosis mixed dementia sangat sulit dan memberikan tantangan tersendiri bagi para klinisi. Pada artikel ini, penulis ingin membahas mengenai tinjauan diagnosis dan tatalaksana mixed dementia. Hasil: Diagnosis mixed dementia dapat menggunakan beberapa kriteria yaitu International Classification of Diseases and Health Related Problems 10th Revision (ICD-10), the Alzheimer’s Disease Diagnost
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Mahalingam, Sowmya, and Ming-Kai Chen. "Neuroimaging in Dementias." Seminars in Neurology 39, no. 02 (2019): 188–99. http://dx.doi.org/10.1055/s-0039-1678580.

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AbstractDementia is a global health issue, the burden of which will worsen with an increasingly aging population. Alzheimer's disease (AD) is the most common dementia, with 50 to 60% of all dementias attributable to AD alone, while the rest are mostly due to frontotemporal lobar dementia, dementia with Lewy bodies, Parkinson's disease dementia, and vascular dementia. Diagnosis of dementias is made clinically with the aid of other testing modalities including neuroimaging. While the role of imaging has traditionally been to exclude reversible causes of dementia, positron emission tomography (PE
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de Mendonça Lima, C. A. "Diagnosis and differential diagnosis of dementia." European Psychiatry 26, S2 (2011): 2108. http://dx.doi.org/10.1016/s0924-9338(11)73811-1.

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The European prevalence of dementias will increase of 40% during the next 40 years, with serious effects on families, communities and healthcare systems (1).A correct diagnosis of dementia is the first step to plan treatment, care and support. There is no single test to identify the cause of dementia. The diagnostic process involves, medical history, mental status exam, physical exam, laboratory tests, psychiatric and (neuro)psychological tests and assessment of individual's functioning. An image of brain is suitable.There is an idea that this diagnostic process can only be realized by highly
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Maxfield, Molly, Allie Peckham, Dara James, Laura Lathrop, and Amy Fiske. "ANTICIPATED SUICIDAL AND DEATH IDEATION IN RESPONSE TO AN IMAGINED DEMENTIA DIAGNOSIS." Innovation in Aging 6, Supplement_1 (2022): 781. http://dx.doi.org/10.1093/geroni/igac059.2824.

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Abstract Alzheimer’s disease and related dementias are prevalent, incurable, and highly impactful diagnoses. Dementias are therefore feared diagnoses. Dementia-related anxiety (DRA) is anxiety about a current or future diagnosis of dementia and the associated complex symptoms. In a mixed methods study, semi-structured interviews were conducted to identify causes of DRA and revealed that numerous adults anticipated suicidal or death ideation if diagnosed with dementia. Fifty cognitively healthy, community-dwelling adults aged 58 to 89 (M = 70.92, SD = 6.08; 64% female) were recruited from a uni
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Roche-Dean, Maria, Sol Baik, Noah Webster, Heehyul Moon, and Laura Zahodne. "FACTORS INFLUENCING DEMENTIA DIAGNOSIS AWARENESS AMONG RACIALLY/ETHNICALLY DIVERSE OLDER ADULTS." Innovation in Aging 8, Supplement_1 (2024): 15. https://doi.org/10.1093/geroni/igae098.0045.

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Abstract Black and Hispanic adults arrive in later life with a greater risk for Alzheimer’s Disease and Related Dementias (ADRD). Untimely dementia diagnoses continue to be a challenge in non-Hispanic Black and Hispanic-identified older individuals, delaying symptom management and access to health services. In this study, we examine whether social factors are associated with awareness of dementia diagnosis among older adults with probable dementia. Data were from the National Health and Aging Trends Study round 1, a nationally representative sample of Medicare beneficiaries aged 65 and older a
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Bourin, Michel. "Vascular Dementia: Definitions, Origins, Symptoms, Diagnosis and Treatments." SAR Journal of Psychiatry and Neuroscience 4, no. 01 (2023): 1–4. http://dx.doi.org/10.36346/sarjpn.2023.v04i01.001.

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Vascular dementia corresponding to intellectual degradation significant enough to disrupt daily life, attributed to cerebral lesions of vascular origin. They are the second cause of dementia after Alzheimer's disease in the defeated countries. Their diagnosis is made difficult, on the one hand by the diversity of lesions potentially responsible for cognitive disorders and on the other hand by their frequent association with Alzheimer's disease. No treatment, other than preventive treatment, has been validated in vascular dementia. Several concepts have attempted or are attempting to characteri
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Salardini, Arash. "Interpretation of Biomarker Data in Diagnosis of Primary Dementias." Seminars in Neurology 39, no. 02 (2019): 200–212. http://dx.doi.org/10.1055/s-0039-1683380.

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AbstractIn the last few years, an improved understanding of dementia biomarkers has significantly increased the diagnostic accuracy for dementias. The National Institutes of Health Biomarkers Definitions Working Group defines a biomarker as “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.” In the field of dementia, a biomarker is a biological measure pointing to a specific dementing pathology. Dementia biomarkers may also serve as surrogates for disease pr
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Tierney, M. C., W. G. Snow, and R. H. Fisher. "Dementia diagnosis." Neurology 39, no. 11 (1989): 1560. http://dx.doi.org/10.1212/wnl.39.11.1560.

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Rai, G. S., and I. Blackman. "Dementia Diagnosis." Clinical Gerontologist 19, no. 4 (1998): 68–70. http://dx.doi.org/10.1300/j018v19n04_07.

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Torian, Lucia, Emily Davidson, George Fulop, Laura Sell, and Howard Fillit. "The Effect of Dementia on Acute Care in a Geriatric Medical Unit." International Psychogeriatrics 4, no. 2 (1992): 231–39. http://dx.doi.org/10.1017/s1041610292001066.

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Treatment of dementia costs billions of dollars in long-term care and community services every year. Dementia also burdens the acute care system and may contribute to financial problems for hospitals serving large numbers of demented elderly. In a specialized geriatric medical unit devoted to acute care of the frail elderly, Alzheimer's disease and vascular and mixed dementias afflicted 63% of inpatients and were associated with excess consumption of nursing resources, complications of treatment, nosocomial infections, lengthy hospitalizations, and financial losses to the hospital. Due in part
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Shih, Ying-Jyun, Jiun-Yi Wang, Su-Yuan Chan, and Yung-Jen Yang. "P203: The temporal relationship between dementia and serious traffic accidents: a cohort study of linked national databases." International Psychogeriatrics 35, S1 (2023): 189–90. http://dx.doi.org/10.1017/s1041610223003344.

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Objective:The traffic issues have been attracting global attention due to increased occurrence and higher mortality rate in the older population. Many countries have employed different kinds of regulations on the elder drivers depending either on their age or whether being demented. These policy differences left a research gap to identify the temporal relationship between serious traffic accidents (STA) and dementias, which can inform the most appropriate time for policymaking. In the present study, we linked two national databases and performed analyses to explore this problem.Methods:With th
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Calvó-Perxas, Laia, María Aguirregomozcorta, Isabel Casas, et al. "Rate of dementia diagnoses according to the degree of aging of the population." International Psychogeriatrics 27, no. 3 (2014): 419–27. http://dx.doi.org/10.1017/s1041610214002130.

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ABSTRACTBackground:There is a lack of information regarding geographical differences in the incidence and prevalence of dementia diagnosis according to the degree of aging of the population. The objectives of this study were to analyze the rate of dementia diagnoses, and to compare the dementia subtypes and the clinical characteristics of the patients depending on the degree of aging of their municipalities.Methods:We used data from the Registry of Dementias of Girona (ReDeGi), containing the cases of dementia diagnosed in the memory clinics of the Health Region of Girona, in Catalonia (Spain)
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Chertkow, H., H. Bergman, H. M. Schipper, et al. "Assessment of Suspected Dementia." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 28, S1 (2001): S28—S41. http://dx.doi.org/10.1017/s0317167100001189.

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At the Second Canadian Consensus Conference on Dementia (CCCD) (February, 1998), a group of neurologists, geriatricians, and psychiatrists met to consider guidelines for evaluation of dementia in Canada. This review paper formed a background paper for their discussion of dementia diagnosis. These experts from across the country concluded that diagnosis of suspected dementia cases continued to rest on skilled clinical assessment. Mental status exam, preferably in some quantifiable form, has become an essential part of the assessment. Selected laboratory tests are advisable in all cases (CBC, TS
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Davis, Laura, and Tom Dening. "Diagnostic, management and nursing challenges of less common dementias: Parkinsonian dementias and Huntington's disease." British Journal of Neuroscience Nursing 17, no. 2 (2021): 68–76. http://dx.doi.org/10.12968/bjnn.2021.17.2.68.

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Background: Although most cases of dementia are caused by Alzheimer's disease or vascular dementia, around 10-15% of cases are due to other disorders, including dementias with Parkinsonian features, Huntington's disease, frontotemporal dementia, human immunodeficiency virus (HIV), and alcohol. Aims: These less common dementias are important as they may have differing clinical features and require different approaches to diagnosis and management. This paper seeks to provide relevant information for nurses about symptoms, diagnosis and management of some of the less common dementias. Methods: Th
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Swanson, Keith A., and Ryan M. Carnahan. "Dementia and Comorbidities: An Overview of Diagnosis and Management." Journal of Pharmacy Practice 20, no. 4 (2007): 296–317. http://dx.doi.org/10.1177/0897190007308594.

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The term “dementia” describes various neurodegenerative disorders that effect cognition, including Alzheimer disease, vascular dementia, and others. This article reviews the diagnosis and management of common types of dementia and comorbidities. Dementias are differentiated clinically by history, symptom presentation, and exclusion of other causes through laboratory and imaging studies. Cholinesterase inhibitors are useful but may not be effective for all types of dementia and provide only modest benefits. Certain medical comorbidities may increase the risk of dementia, although genetics are a
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Sianturi, Aditya Gloria Monalisa. "Stadium, Diagnosis, dan Tatalaksana Penyakit Alzheimer." Majalah Kesehatan Indonesia 2, no. 2 (2021): 39–44. http://dx.doi.org/10.47679/makein.202132.

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Dementia is a general term for loss of memory that can occur along with behavioral or psychological symptoms in patients. The first cause of dementia patients is Alzheimer's disease. Alzheimer’s disease is a brain degenerative disease and the most common cause of dementia. In Alzheimer’s disease, there are three development stages, which is stage 1, stage 2, and stage 3 with different clinical symptoms at each stage. There are several clinical criteria for establishing a definitive diagnosis of Alzheimer’s disease and also support examinations have to be carried out. Until now, Alzheimer’s tre
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Morgan, Debra, Melanie Funk, Margaret Crossley, Jenny Basran, Andrew Kirk, and Vanina Dal Bello-Haas. "The Potential of Gait Analysis to Contribute to Differential Diagnosis of Early Stage Dementia: Current Research and Future Directions." Canadian Journal on Aging / La Revue canadienne du vieillissement 26, no. 1 (2007): 19–32. http://dx.doi.org/10.3138/1457-2411-v402-62l1.

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ABSTRACTEarly differential diagnosis of dementia is becoming increasingly important as new pharmacologic therapies are developed, as these treatments are not equally effective for all types of dementia. Early detection and differential diagnosis also facilitates informed family decision making and timely access to appropriate services. Information about gait characteristics is informative in the diagnostic process and may have important implications for discriminating among dementia subtypes. The aim of this review paper is to summarize existing research examining the relationships between gai
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Livingston, Gill, Karen Sax, Jo Willison, Bob Blizard, and Anthony Mann. "The Gospel Oak Study stage II: the diagnosis of dementia in the community." Psychological Medicine 20, no. 4 (1990): 881–91. http://dx.doi.org/10.1017/s0033291700036588.

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SynopsisAn attempt was made to assess in detail subjects screened as suffering from dementia among a North London community sample of elderly people. Forty-eight (80 %) subjects were interviewed, 7 (12%) were found to have died and 5 (8%) either refused interview or were lost to follow-up. By clinicians' diagnosis of the 48 interviewed, 22 subjects (46%) had probable Alzheimer's disease, one had multi-infarct dementia, five had mixed dementia, five had secondary dementia, 10 had a dementia which could not be further classified and 5 were not demented. No subject had a reversible condition. The
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Benke, Thomas, and Elfriede Karner. "The Neuropsychological Assessment of Dementia." CNS Spectrums 7, no. 5 (2002): 371–75. http://dx.doi.org/10.1017/s109285290001782x.

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ABSTRACTIt has become standard practice to base the diagnosis of dementia on the combination of neuropsychological and non-behavioral findings. The present article provides a short, clinically oriented synopsis of the targets, investigational procedures, and difficulties of the modern neuropsychological approach to the diagnosis of dementia. Over the years, neuropsychology has developed assessment tools to evaluate the cognitive and behavioral abnormalities of many dementias. Validated tests of memory, language, executive, and other cognitive functions are used to screen for dementia and ident
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Feldman, H., and A. Kertesz. "Diagnosis, Classification and Natural History of Degenerative Dementias." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 28, S1 (2001): S17—S27. http://dx.doi.org/10.1017/s0317167100001177.

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The release of the first approved medications for the treatment of Alzheimer’s disease in Canada has highlighted the renewed need and importance of diagnostic accuracy and understanding of the spectrum of the dementias. The epidemiological scope of the problem of dementia in Canada including risk factors, caregiving patterns and costs of care have been well-characterized through the Canadian Study of Health and Aging (CSHA 1991-1996) with some of the key findings reviewed here. Beyond Alzheimer’s disease the phenotypes and genotypes of the other degenerative dementias have been emerging with p
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Li, Xia, Qi Qiu, Yinghua Yang, et al. "BUILDING A CONTINUOUS DEMENTIA MANAGEMENT MODEL IN COMMUNITIES OF SHANGHAI." Innovation in Aging 3, Supplement_1 (2019): S444. http://dx.doi.org/10.1093/geroni/igz038.1665.

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Abstract Over 10 million people with Alzheimer’s disease or related dementias (ADRD) live in China. In Shanghai, the prevalence of ADRD is about 3-4% among aged 60 or older, and approximately 70-85% have never been diagnosed. This study reported the pilot testing results of a dementia management model launched by Shanghai Mental Health Center to build dementia friendly communities. The dementia management model links screening, diagnosis, care planning, treatment, and services, to improve dementia literacy and standard diagnosis rate. About 3,786 senior residents were screened using the AD 8 a
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Sandilyan, Malarvizhi Babu, and Tom Dening. "Diagnosis of dementia." Nursing Standard 29, no. 43 (2015): 36–41. http://dx.doi.org/10.7748/ns.29.43.36.e9441.

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Grossberg, George T. "DIAGNOSIS OF DEMENTIA." American Journal of Geriatric Psychiatry 7 (September 1999): 15. http://dx.doi.org/10.1097/00019442-199911001-00048.

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Nicholl, C. "Diagnosis of dementia." BMJ 338, jun08 3 (2009): b1176. http://dx.doi.org/10.1136/bmj.b1176.

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DiSantostefano, Jan. "Dementia Diagnosis Coding." Journal for Nurse Practitioners 14, no. 3 (2018): 148–52. http://dx.doi.org/10.1016/j.nurpra.2017.09.019.

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Byszewski, Anna M., Frank J. Molnar, Faranak Aminzadeh, Marg Eisner, Fauzia Gardezi, and Raewyn Bassett. "Dementia Diagnosis Disclosure." Alzheimer Disease & Associated Disorders 21, no. 2 (2007): 107–14. http://dx.doi.org/10.1097/wad.0b013e318065c481.

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Meiran, Nachshon. "Diagnosis of Dementia." Archives of Neurology 53, no. 10 (1996): 1043. http://dx.doi.org/10.1001/archneur.1996.00550100129022.

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Davis, Laura, Zarina Karim, and Tom Dening. "Diagnostic, management and nursing challenges of less common dementias: Frontotemporal dementia, alcohol-related dementia, HIV dementia and prion diseases." British Journal of Neuroscience Nursing 18, no. 1 (2022): 26–37. http://dx.doi.org/10.12968/bjnn.2022.18.1.26.

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Background: Most cases of dementia are due to Alzheimer's disease or vascular dementia, but attention on these disorders means that other important causes of dementia may be relatively neglected. About 10–15% of people with dementia have other diagnoses, and there are numerous causes of the less common types of dementia. Aims: This paper provides information about the causes, symptoms, diagnosis and nursing management of some of the different types of less common dementias, with the aim of helping nurses to provide better care to patients and families affected. Methods: This is one of two conn
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Gottfries, C. G. "Classifying Organic Mental Disorders and Dementia—A Review of Historical Perspectives." International Psychogeriatrics 3, S1 (1991): 9–17. http://dx.doi.org/10.1017/s1041610205001092.

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The concept of dementia should not be used synonymously with the concept of organic mental disorders. By definition, according to DSM-III and ICD-10, dementia is a syndrome which includes memory impairment. The severity of the disorder is disabling and the course is chronic. Differential diagnosis includes age-associated memory impairment (AAMI), delirium, and depressive disorders. The dementias may be subdivided into four groups: idiopathic (primary degenerative dementias), vascular, secondary, and others. The idiopathic dementias are those in which etiology is assumed to be found within the
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Chiong, Winston, Amy Y. Tsou, Zachary Simmons, Richard J. Bonnie, and James A. Russell. "Ethical Considerations in Dementia Diagnosis and Care." Neurology 97, no. 2 (2021): 80–89. http://dx.doi.org/10.1212/wnl.0000000000012079.

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Alzheimer disease and other dementias present unique practical challenges for patients, their families, clinicians, and health systems. These challenges reflect not only the growing public health effect of dementia in an aging global population, but also more specific ethical complexities including early loss of patients' capacity to make decisions regarding their own care, the stigma often associated with a dementia diagnosis, the difficulty of balancing concern for patients' welfare with respect for patients' remaining independence, and the effect on the physical, emotional, and financial we
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Bradley, Danielle, Joanna Harrison, Mark Goodall, and Richard Dobrashian. "Are advanced clinical practitioners perfectly placed to re-report neuroimages to support the clinical diagnosis of dementia?" International Journal for Advancing Practice 1, no. 3 (2023): 146–50. http://dx.doi.org/10.12968/ijap.2023.1.3.146.

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As the global population continues to age, the prevalence of dementia is increasing worldwide. While there is an emphasis on early, timely diagnosis and treatment options for people with a dementia, wait times from referral to diagnosis have increased. Neuroimaging performed by radiologists can be utilised to support dementia diagnoses. The purpose of this commentary is to consider whether advanced clinical practitioners, who specialise in dementia, are well placed to re-report on pre-existing neuroimages to support a clinical diagnosis of dementia.
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Enache, D., S. M. Fereshtehnejad, P. Cermakova, et al. "Antidepressants and mortality risk in a dementia cohort – data from SveDem, the Swedish Dementia Registry." European Psychiatry 33, S1 (2016): S85. http://dx.doi.org/10.1016/j.eurpsy.2016.01.039.

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BackgroundThe association between mortality risk and use of antidepressants in people with dementia is unknown.ObjectiveTo describe the use of antidepressants in people with different dementia diagnoses and to explore mortality risk associated with use of antidepressants 3 years before a dementia diagnosis.MethodsStudy population included 20,050 memory clinic patients from Swedish Dementia Registry diagnosed with incident dementia. Data on antidepressants dispensed at the time of dementia diagnosis and during three-year period before dementia diagnosis was obtained from the Swedish Prescribed
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Salihovic, Denisa, Dzevdet Smajlovic, Zikrija Dostovic, and Adnan Dostovic. "Mini Mental Status Examination vs. Montreal Cognitive Assessment For Early Diagnosis Of Vascular Dementia." Journal of Psychological Medicine 11, no. 1 (2025): 1–5. https://doi.org/10.52338/jopm.2025.4819.

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Background: The Mini Mental Status Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are the most commonly used scales to detect mild cognitive impairment in population-based epidemiologic studies. The aim of this study was to define which test is more reliable for early diagnosis of vascular dementia – MoCA or MMSE. Material and methodes: This prospective study included 274 patients with acute stroke, both sexes and all age groups. Patients were divided into groups: demented (DP) and non-demented (NDP). Each patient was underwent to a clinical examination and scoring with appropriat
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Rañola, Madelaine B. "Lewy body Dementia: What are the challenges of early and accurate diagnosis?" Australasian Journal of Neuroscience 32, no. 1 (2022): 40–51. https://doi.org/10.21307/ajon-2022-005.

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Abstract Collectively, Lewy Body Dementia (LBD) including Parkinson’s Disease Dementia (PDD) and dementia with Lewy Bodies (DLB) account for the second leading type of dementia following Alzheimer’s disease (AD) (Lee et al., 2019). Despite revised consensus criteria, detection rates in routine clinical practice remain poor (Vann Jones & O’Brien, 2013) with cases commonly misdiagnosed as AD (McKeith et al., 2017). Diagnosis can be challenging due to the presentation of an extensive range of autonomic, motor, sleep, cognitive and neuropsychiatric symptoms which can vary within a person and b
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Ludin. "Diagnosis and differential diagnosis of dementia." Therapeutische Umschau 56, no. 2 (1999): 74–78. http://dx.doi.org/10.1024/0040-5930.56.2.74.

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Die Kriterien und Probleme bei der Diagnostik dementieller Syndrome werden geschildert. Aus neurologischer Sicht werden die wichtigsten Differentialdiagnosen dargestellt, wobei besonderes Gewicht auf potentiell behandelbare Krankheiten und Syndrome gelegt wird.
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Amjad, Halima, Marcela Blinka, Jennifer Aufill, and Quincy Samus. "Dementia Diagnosis and Challenges in Minority Populations." Innovation in Aging 4, Supplement_1 (2020): 161–62. http://dx.doi.org/10.1093/geroni/igaa057.525.

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Abstract Alzheimer’s disease and related dementias are underdiagnosed in the United States, with potentially higher rates of underdiagnosis among minority groups. Our objective was to examine perceptions of dementia, the utility and timeliness of diagnosis, and experiences obtaining diagnosis and care in minorities. We recruited 17 family caregivers of African American (n=11), Latino (n=3), and Asian (n=3) persons with dementia (PWD) to complete surveys and semi-structured interviews. Caregivers were mostly female (n=14), children of PWD (n=14), and had greater than high school education (n=16
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Bello, Valeska Maria Eboli, and Rodrigo Rizek Schultz. "Prevalence of treatable and reversible dementias: A study in a dementia outpatient clinic." Dementia & Neuropsychologia 5, no. 1 (2011): 44–47. http://dx.doi.org/10.1590/s1980-57642011dn05010008.

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Abstract Dementia is a syndrome characterized by the development of multiple cognitive deficits and behavioral changes that leads to impairment of functional activities. There are primary degenerative, progressive and irreversible dementias, and other dementias resulting from a progressive but potentially reversible dementia of secondary origin. Objective: To assess the prevalence of cases with a diagnosis of potentially reversible dementia at a Behavioral Neurology Outpatient Unit. Methods: A retrospective study based on a review of 340 medical records of patients seen from 1999 to 2009 was c
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Lazarević, Marija. "Dementia: Etiology and clinical presentation." Galenika Medical Journal 3, no. 12 (2024): 75–85. https://doi.org/10.5937/galmed2412066l.

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Dementia means persistent deterioration of intellectual and cognitive functions with little or no impairment of consciousness/awareness or perception. There are several types of dementia, but the most common in everyday practice are: Alzheimer's disease, dementia with Lewy bodies (DLT), frontotemporal dementia (FTD), vascular dementia, and dementia due to hydrocephalus. In 10-15% of cases, dementias are reversible because they arose as a clinical manifestation of some other disease that can be treated and cured. This is particularly important for doctors in primary health care, who should reco
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Antunes Pereira, Daniel, Shara Aline Bueno Dantas, Marco Antônio Orsini Neves, Everton Gonçalves Pinto, Gilberto Canedo Martins Jr, and Antonio Marcos da Silva Catharino. "Frontotemporal dementia: From the clinic to the differential diagnosis." International Journal of Case Reports and Images 14, no. 1 (2023): 28–32. http://dx.doi.org/10.5348/101377z01dp2023cr.

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Introduction: Frontotemporal dementia (FTD) is a disease that encompasses several syndromes that differ in their cognitive, behavioral, language signs, and motor phenomena. Only Alzheimer’s disease causes more early-onset dementia cases than FTD. According to World Health Organization (WHO) projections, dementia rates will double every 20 years and reach 115.4 million people in 2050, ranging from 3% to 26%. The FTD spectrum encompasses three variant syndromes, namely the behavioral variant, the semantic variant, and the non-fluent/agrammatical variant. Frontotemporal lobar degeneration is neur
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Crowley, S., and E. Dunne. "Prevalence of Dementia, associated Co-morbidities, and Multidisciplinary Team Involvement in a Psychiatry of Old Age Service." European Psychiatry 67, S1 (2024): S637. http://dx.doi.org/10.1192/j.eurpsy.2024.1320.

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IntroductionDementia is a common diagnosis in service users seen by Psychiatry of Old Age (POA) Services. This clinical audit was conducted prior to the services engagement with a focus group, which aimed to explore the implementation of the “Appropriate prescribing of psychotropic medication for non-cognitive symptoms in people with dementia” (National Clinical Guideline No. 21) and identify additional resource requirements to be submitted for consideration by the HSE’s estimate process for 2023.ObjectivesIts aims were to evaluate:•The prevalence of service users with a dementia diagnosis amo
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Schröder, Sebastian, Johannes Heck, Adrian Groh, et al. "White Blood Cell and Platelet Counts Are Not Suitable as Biomarkers in the Differential Diagnostics of Dementia." Brain Sciences 12, no. 11 (2022): 1424. http://dx.doi.org/10.3390/brainsci12111424.

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Abstract: Apart from Alzheimer’s disease (AD), no biomarkers for the differential diagnosis of dementia have been established to date. Inflammatory processes contribute to the pathogenesis of dementia subtypes, e.g., AD or frontotemporal dementia (FTD). In the context of cancer or cardiovascular diseases, white blood cell (WBC) populations and platelet counts, as well as C-reactive protein (CRP), have emerged as biomarkers. Their clinical relevance in dementia, however, is currently only insufficiently investigated. In the present study, hematological and inflammatory parameters were measured
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Quinn, Terence J., and Jenny McCleery. "Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’." Clinical Science 131, no. 8 (2017): 729–32. http://dx.doi.org/10.1042/cs20170025.

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In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline. The authors conclude that diagnostic neuroimaging in dementia should shift from whole-brain evaluation to focused quantitative analysis of strategic brain areas. This commentary uses the review of lesion location mapping to discuss broader issues around studies of dementia test strategies. We draw upon work completed by the Cochrane Dementia and Cognitive Improvement Group designed to improve design, cond
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Velakoulis, Dennis, and John H. Lloyd. "The Role of SPECT Scanning in a Neuropsychiatry Unit." Australian & New Zealand Journal of Psychiatry 32, no. 4 (1998): 511–22. http://dx.doi.org/10.3109/00048679809068325.

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Objectives: Single photon emission computerised tomography (SPECT) studies allow the assessment of cerebral blood flow and have been increasingly used as a clinical tool in neurology and neuropsychiatry. This paper examines the contribution of SPECT to the clinical management of patients with neuropsychiatric disorders, in particular patients with atypical or early onset dementia. Method: All patients admitted to an eight-bed neuropsychiatry unit in a general hospital setting who had undergone SPECT scanning over a 15–month period were reviewed. Information was collected on clinical diagnosis,
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Oh, Chorong, and Leonard LaPointe. "“Where is Dementia?” A Systematic Literature Review Exploring Neuroanatomical Aspects of Dementia." Perspectives of the ASHA Special Interest Groups 2, no. 15 (2017): 9–23. http://dx.doi.org/10.1044/persp2.sig15.9.

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Dementia is a condition caused by and associated with separate physical changes in the brain. The signs and symptoms of dementia are very similar across the diverse types, and it is difficult to diagnose the category by behavioral symptoms alone. Diagnostic criteria have relied on a constellation of signs and symptoms, but it is critical to understand the neuroanatomical differences among the dementias for a more precise diagnosis and subsequent management. With this regard, this review aims to explore the neuroanatomical aspects of dementia to better understand the nature of distinctive subty
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Wollney, Easton N., Carma L. Bylund, Noheli Bedenfield, et al. "Clinician approaches to communicating a dementia diagnosis: An interview study." PLOS ONE 17, no. 4 (2022): e0267161. http://dx.doi.org/10.1371/journal.pone.0267161.

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Background Individuals with cognitive impairment and their families place a high value on receiving a dementia diagnosis, but clinician approaches vary. There is a need for research investigating experiences of giving and receiving dementia diagnoses. The current study aimed to investigate clinician approaches to giving dementia diagnoses as part of a larger study investigating patient, caregiver, and clinician experiences during the diagnosis encounter. Method Investigators conducted telephone interviews with Florida-based clinicians who give dementia diagnoses either rarely or commonly. Inte
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Martins, Leonardo Tafarello, Ivan Abdalla Teixeira, Jerson Laks, and Valeska Marinho. "Recognizing Late Onset Frontotemporal Dementia with the DAPHNE scale: A case report." Dementia & Neuropsychologia 12, no. 1 (2018): 75–79. http://dx.doi.org/10.1590/1980-57642018dn12-010011.

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ABSTRACT Frontotemporal dementias are classically described as early onset dementias with personality and behavioral changes, however, late onset forms can also be found. Considering the paucity of information about late onset behavioral variant frontotemporal dementia and its challenging diagnosis, we present a case report of an 85-year-old woman with behavioral changes and slow progression to dementia who was first diagnosed as having bipolar disorder and then Alzheimer's disease. The Daphne scale provided a structured means to improve clinical diagnosis, also supported by characteristic fea
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Chen, Yingjia, Thomas John Semrad, Rosemary Donaldson Cress, and Laurel A. Beckett. "Effect of dementia diagnosis on receipt of postoperative colon cancer chemotherapy." Journal of Clinical Oncology 33, no. 3_suppl (2015): 769. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.769.

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769 Background: Colon cancer and dementia have a high risk of co-occurrence. Prior studies found that patients with dementia have higher mortality than non-demented counterparts, mostly from non-cancer causes. We hypothesized that a dementia diagnosis using an improved algorithm would be associated with reduced use of postoperative therapy. Methods: In addition to the claims-based algorithm for dementia published by Centers for Medicare and Medicaid Services that uses SEER-Medicare Medicare Provider Analysis and Review, Carrier Claims, Home Health Agencies, and Outpatient files, we developed a
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Nakaoku, Yuriko, Yoshimitsu Takahashi, Shinjiro Tominari, and Takeo Nakayama. "Predictors of New Dementia Diagnoses in Elderly Individuals: A Retrospective Cohort Study Based on Prefecture-Wide Claims Data in Japan." International Journal of Environmental Research and Public Health 18, no. 2 (2021): 629. http://dx.doi.org/10.3390/ijerph18020629.

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Preventing dementia in elderly individuals is an important public health challenge. While early identification and modification of predictors are crucial, predictors of dementia based on routinely collected healthcare data are not fully understood. We aimed to examine potential predictors of dementia diagnosis using routinely collected claims data. In this retrospective cohort study, claims data from fiscal years 2012 (baseline) and 2016 (follow-up), recorded in an administrative claims database of the medical care system for the elderly (75 years or older) in Niigata prefecture, Japan, were u
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Roberts, Jennifer, and Gill Windle. "P84: This has been far from easy: How do people affected by dementia in Wales experience their diagnosis, and how can it be improved?" International Psychogeriatrics 35, S1 (2023): 246–47. http://dx.doi.org/10.1017/s104161022300409x.

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Background:The Dementia Action Plan for Wales (UK), published in 2018, includes aims for improving assessment and diagnosis, as well as suggestions for what might characterise services that provide optimal support. Wales is a largely rural country, a factor shown previously to impede access to services. Suitable support for people living with rarer dementias is also limited, which may be further exacerbated by living in a rural area. This a relatively unexplored area of research.Objectives:This study explored diagnosis and post-diagnostic support experiences of people affected by dementia acro
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