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1

Hart, Sawyer(Sawyer H. ). "Re-strengthening demineralized bone via tannin-iron crosslinking." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/124588.

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Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2019<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages [30]-[31]).<br>As the world population continues to age, the social and economic impacts resulting from osteoporosis will continue to rise. New treatments for the disease are needed now more than ever. Using tannin iron complexes we show that thin film deposition of the complexes are not only possible but effective at strengthening demineralized bone. Furthermore we show that by taking advantage of newl
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黃美娟 and May-kuen Alice Wong. "Bone induction of demineralized intramembranous and endochondral bone matrices." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3197305X.

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Wong, May-kuen Alice. "Bone induction of demineralized intramembranous and endochondral bone matrices." View the Table of Contents & Abstract, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21872752.

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Klopper, Lucinda. "The behaviour of potassium and sodium species during the thermal treatment of a demineralized Highveld coal / Lucinda Klopper." Thesis, North-West University, 2011. http://hdl.handle.net/10394/8411.

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A series of experiments was conducted to investigate the potential influence of pre- and post adding of catalysts to a demineralized coal char. The catalysts were chosen according to yield better catalytic activity and be inexpensive. CO2 gasification was conducted on the samples in a temperature range of 500 °C to 900 °C. The coal chosen was a high-inertinite, high-ash, Highveld bituminous coal. The catalysts chosen were sodium carbonate, potassium carbonate, and a mixture of the two catalysts. Different methods were used to investigate the factors influencing the reactivity of the deminerali
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The, Patricia Maria Soares Lima. "Effectiveness of different excavation methods on removal of artificially demineralized dentin." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=8882.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>The aim of this study was to evaluate the effectiveness of three mechanical methods for removal of demineralized dentin. A total of thirty sound human third molars indicated for extraction. After extraction, the teeth were cleaned and stored properly. The occlusal enamel was removed with a diamond wheel to expose a flat dentin surface, and each tooth was sectioned longitudinally in the buccal-lingual direction. One half of each tooth was entirely covered with an acid-resistant varnish, except for an occlusal area of 16 mm2, and was
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Willmot, Derrick Robert. "Measurement of demineralised white enamel associated with orthodontic treatment." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340219.

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Elnikety, S. "A new application of demineralised bone as a tendon graft." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1473214/.

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Tendon injuries present a challenging situation for orthopaedic surgeons. In severe injuries, a tendon transfer or a tendon graft is usually used. The aim is to find a biocompatible substance with mechanical and structural properties that replicate those of normal tendon. Because of its structural and mechanical properties, we propose that Demineralised Cortical Bone (DCB) can be used in the repair of tendon and ligament, as well as for the regeneration of the enthesis. I hypothesise that DCB grafted in a tendon environment will result in remodelling of the DCB into tendon and produce a fibroc
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IWATA, HISASHI, MINORU UEDA, KAZUHIKO MERA, and HIDEKI MIZUTANI. "A STUDY OF THE BONE MORPHOGENETIC PROTEIN DERIVED FROM BOVINE DEMINERALIZED DENTIN MATRIX." Nagoya University School of Medicine, 1996. http://hdl.handle.net/2237/16100.

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Chay, Siew Han. "Vascular endothelial growth pattern during demineralized bone matrix (intramembranous bone origin) induced osteogenesis." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628417.

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Wong, Wing-kit Ricky, and 黃永傑. "The effect of demineralized intramembranous bone matrix on the healingof autogenous bone grafts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31973061.

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謝秀嫻 and Siew Han Chay. "Vascular endothelial growth pattern during demineralized bone matrix (intramembranous bone origin) induced osteogenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B38628417.

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Wong, Wing-kit Ricky. "The effect of demineralized intramembranous bone matrix on the healing of autogenous bone grafts." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B31973061.

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Peng, Jingyuan, and 彭靖园. "Morphological and quantitative analysis of silver compounds on demineralised dentine in saliva substitutes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/197082.

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Silver compounds have become popular for the treatment of arresting dental caries and dentine hypersensitivity. This study investigated the interaction of silver compounds in demineralised dentine under different conditions. Scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), ion chromatography (IC) and inductively coupled plasma-mass spectroscopy (ICP-MS) were used to analyse these interactions. A systematically-approached literature review was conducted on silver compounds in dentistry. They have been
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Blice, Rebecca L. "EFFICACY OF DEMINERALIZED BONE MATRIX AS AN OSTEOINDUCTIVE AGENT WHEN USING A BETA-TRICALCIUM PHOSPHATE CARRIER." University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1162918440.

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Stoianovici, Charles. "Directing Mesenchymal Stem Cells for Periodontal Regeneration." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5335.

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Background: Directing autogenous Mesenchymal Stem Cell (MSC) to defect sites has a great promise in bone regeneration. We designed a MSC specific, bone affinity peptide (E7HA7) by conjugating E7 with a polyglutamate hydroxyapatite (HA) binding motif. We sought to characterize the in-vivo releasing pattern and bioactivity of E7HA7. Methods: HA discs were coated with fluorescent labeled peptides E7HA7, E7HA2 or E7 were subcutaneously implanted in Sprague Dawley rats. In an ectopic bone formation model was used to test the in-vivo bioactivity of E7HA7 conjugated to DBM. Results: E7HA7 showed slow
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Thangarajah, T. "Augmentation of rotator cuff tendon-bone healing using demineralised bone matrix and mesenchymal stem cells." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10027670/.

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BACKGROUND: The results of surgery for tears of the rotator cuff are variable, with failure occurring in up to 94% of cases. Demineralised bone matrix (DBM) consists of a collagen scaffold containing multiple growth factors and has been used successfully to improve tendon-bone healing. By combining DBM with stem cells its effects may be enhanced given that many of the growth factors it contains are able to direct stem cell differentiation down tenogenic, chondrogenic, and osteogenic lineages. These cell lines produce elements essential to the formation of a naturally graded enthesis. AIM: To i
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Shahbazi, Shirin. "Biological augmentation of the tendon-bone enthesis using demineralised bone matrix and mesenchymal stem cells." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10060766/.

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Rotator cuff (RC) injuries are among the most common upper limb injuries, causing impaired function and pain for patients, as well as resulting in a significant financial burden for health care providers. Chronic RC tears are associated with tendon retraction from the bone surface making their surgical repairs challenging. In order to enhance the outcome of these surgeries, different grafts have been investigated however, these do not restore the biological and functional properties of the native enthesis. This study aims to investigate the use of demineralised bone matrix (DBM) with cells as
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周明忠 and Ming-chung Chow. "The healing of endochondral bone grafts in the presence of the demineralized intramembranous bone matrix: :a qualitative andquantitative analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B38628429.

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Avery, Steven. "Assessment of the bioactive potential of demineralised dentine matrix on bone marrow-derived, mesenchymal stem cells." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/97262/.

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At present, the prime candidate for augmentation of bone defects are autologous bone grafts (ABGs), owing to their ability to emulate the physiological signalling environment to induce bone marrow-derived, mesenchymal stem cells (BMMSCs) to differentiate into functional osteoblasts. However, the uses of ABGs are negated due to patient complications. Dentine matrix has recently become increasingly recognised as possessing bioactive nature and has demonstrated the ability to augment bone repair in vivo. However, the constituents of dentine that confer efficacy for bone formation are poorly under
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Aden, Abdirahman. "Developing optical coherence tomography for the quantitative study of erosive and carious lesions in dental enamel in vitro." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/31707.

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Optical Coherence Tomography (OCT) is an imaging technique that uses near infra-red light to non-invasively form cross-sectional images of specimens, in a similar way to ultrasound and RADAR. A number of research groups have used OCT to study natural and artificial carious lesions and to some extent erosive lesions. For this, a variety of in vitro models have been used. However, the exact mechanism by which these demineralised enamel lesions affect the OCT measurements is not fully understood. This remains a barrier to its adoption as both an analytical laboratory tool and a widespread techniq
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Bourke, Jared. "Preparation and Properties of Natural, Demineralized, Pure, and Doped Carbons from Biomass; Model of the Chemical Structure of Carbonized Charcoal." The University of Waikato, 2007. http://hdl.handle.net/10289/2330.

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Pioneering work performed by Rosalind Franklin over half a century ago provided the first structural models of two distinct carbon types: those that become graphitic during carbonization at high temperatures, and those that do not. Moreover it is known that certain properties of carbonaceous materials including combustion, surface area, electrical resistivity, and catalytic properties are influenced by mineral impurities. The nature of this division in biocarbon structure and the known effects of minerals on carbon properties have led to this work; three principal topics were addressed; (1) t
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Chow, Ming-chung. "The healing of endochondral bone grafts in the presence of the demineralized intramembranous bone matrix :a qualitative and quantitative analysis." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628429.

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Bezerra, Maria Denise Rodrigues de Moraes. "Analysis of the action of catechins derived from green tea in erosively demineralized human dentine: in vitro and in situ studies." Universidade Federal do CearÃ, 2016. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=18736.

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CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior<br>O presente estudo avaliou a aÃÃo de catequinas do chà verde em dentina humana sob situaÃÃo de desafio erosivo e originou trÃs capÃtulos. Nos dois primeiros, blocos de dentina humana (n=10) coronÃria ou radicular (4x4x2mm) foram imersos em saliva (2h) para formaÃÃo de pelÃcula adquirida. Foram submetidos de forma cÃclica (3x/dia-3 dias) ao desafio erosivo pela imersÃo em Ãcido cÃtrico (60s), seguido pelos tratamentos: G1-Ãgua destilada (AD), G2-SoluÃÃo de gluconato de clorexidina 0,12% (CLX), G3-InfusÃo de chà verde (CV). Os espÃcime
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Jackson, Michael T. 1969. "Assessment of the closure of critical sized defects in the rabbit calvarium utilizing demineralized bone matrix putty as an allogenic graft material." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=78389.

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Closure of bone defects that do not heal spontaneously require some form of bone inducing agent in order to ensure complete repair. Autogenous bone is the clinical gold standard for the management of these types of defects. Present research is aimed at finding acceptable alternatives to harvesting autogenous bone grafts in patients for obvious reasons. Recent literature supports that demineralized bone matrix (DBM) is osteoinductive, although this is not the case for all commercially available forms of DBM.<br>An in vivo study was conducted which attempted to evaluate the healing of cri
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Ruiz, Guillen Antonio. "Respuesta del disco invertebralde de la rata a la introducción en su interior de substratos orgánicos inductores de la osificación." Doctoral thesis, Universitat Rovira i Virgili, 1993. http://hdl.handle.net/10803/8867.

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Poirier, Christel. "L'eau à l'hôpital." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2P093.

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Lima, Carlos Eugenio Villaboim de Castro. "Influência da associação da sinvastatina à matriz de osso desmineralizado bovino na reparação de defeitos ósseos em calvária de ratos." Universidade de Taubaté, 2008. http://www.bdtd.unitau.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=457.

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A reparação de defeitos ósseos é uma preocupação constante em diversas áreas da odontologia. Vários materiais são usados com a finalidade de ajudar e acelerar esta reparação, tais como enxertos autógenos, xenógenos, membranas e alguns medicamentos, assim como a associação de alguns destes métodos. A sinvastatina, medicamento utilizado para redução de colesterol, em alguns estudos, tem demonstrado ação na estimulação de formação óssea. O objetivo do presente estudo foi avaliar a influência da associação da sinvastatina à matriz desmineralizada de osso bovino na reparação de defeitos ósseos em c
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Holland, Andrew D. "Examining the taphonomic challenges to the 3D digitisation of fragmented bone." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/15180.

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The utilisation of 3D digitisation and visualisation has grown considerably since 2008 and is becoming an increasingly useful tool for the digital documentation and metric analysis of archaeological artefacts and skeletal remains. It provides public access to rare and fragile specimens of palaeontological and palaeopathological importance whilst reducing the physical impact on these remains. Research in engineering and computer vision provides some insight into the impact of surface properties such as colour, specularity, reflectance and shape on the quality of the recorded 3D image, but withi
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Olivier, Johannes Petrus Jacobus. "Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial." Diss., University of Pretoria, 2020. http://hdl.handle.net/2263/75860.

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Aim: With dental implant treatment having evolved into a very regularly applied treatment modality, post-extraction grafting of extraction sockets with DFDBA in an effort to anticipate and pre-empt post-extraction bone loss has become common practice – clinically known as ridge preservation procedures. The aim of this study was however to histologically determine the quality of bone available for implant placement using DFDBA as grafting material in combination with a resorbable collagen membrane, compared to bone in extraction sockets that were left to heal naturally. Method: Twenty sites
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Antebi, Uri. "Efeitos da radiação ionizante nas proteínas presentes em ossos humanos desmineralizados, liofilizados ou congelados." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-06102015-102027/.

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Os tecidos ósseos alógenos são utilizados nas cirurgias de reconstrução ortopédicas e odontológicas. O número crescente de transplantes de ossos na última década beneficia diversos pacientes. Os profissionais dos Bancos de Tecidos utilizam protocolos que reduzem os riscos de transmissão de doenças infectocontagiosas, entretanto, não eliminam esta possibilidade. Portanto, é importante que tecidos sejam esterilizados por um método eficaz, sendo usualmente aplicada a radiação ionizante. Porém, a radiação ionizante pode acarretar alterações estruturais e biológicas nos ossos em relação à dose. O o
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Öberg, Sven. "Bone Healing after implantation of bone substitute materials. Experimental studies in estrogen deficiency." Doctoral thesis, Umeå University, Odontology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-138.

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<p>Bone formation and bone healing were studied in the mandible, tibia and skull bones in adult, healthy and estrogen deficient rabbits implanted with different bone substitutes. </p><p>In the first study an evaluation of the differences in bone regeneration in and around solid (Alveograf *) and porous hydroxyapatite (Interpore 200*) was undertaken. The implant material was placed into experimentally made bone defects and in half of the defects hydroxyapatite was mixed with a fibrin sealant (Tisseel *). The material alone or mixed with Tisseel was also placed subperiostally in the mandible. Th
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Xie, Shuqiao. "Characterisation of time-dependent mechanical behaviour of trabecular bone and its constituents." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31389.

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Trabecular bone is a porous composite material which consists of a mineral phase (mainly hydroxyapatite), organic phase (mostly type I collagen) and water assembled into a complex, hierarchical structure. In biomechanical modelling, its mechanical response to loads is generally assumed to be instantaneous, i.e. it is treated as a time-independent material. It is, however, recognised that the response of trabecular bone to loads is time-dependent. Study of this time-dependent behaviour is important in several contexts such as: to understand energy dissipation ability of bone; to understand the
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Shih-YunLin and 林詩韻. "Biomechanical Investigation of Demineralized and Remineralized Dentin." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/31648507243667507381.

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Lam, Stephanie. "Bone growth following demineralized bone matrix implantation requires angiogenesis." Thesis, 2014. https://hdl.handle.net/2144/14320.

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Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear. In this study, we utilize an in vivo model of endochondral ossification in mice by implanting demineralized bone matrix (DBM) proximal to the femur to induce ectopic bone formation. TNP-470, a drug known to be anti-angiogenic, was used to inhibit vascularization during the time course of de novo bone formation in order to define the role of angiogenesis during the chondrogenic phase of endochondral bone
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Ngo, Hien. "Ionic exchanges between glass ionomers and demineralised dentine." Thesis, 2005. http://hdl.handle.net/2440/37737.

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Glass-ionomer cement has been used in the Atraumatic Restorative Technique (ART) for stabilisation of carious lesions. The infected layer or fully demineralised dentine is removed by dental hand instruments only and glass-ionomer cement is placed to restore the lesion leaving the affected layer or partly demineralised dentine underneath. There are many anecdotal and some published reports of the ability of these materials to remineralise partly demineralised dentine. The major objectives of this investigation are: 1. To scientifically demonstrate the ability of glass-ionomers to remineralise p
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Ngo, Hien. "Ionic exchanges between glass ionomers and demineralised dentine." 2005. http://hdl.handle.net/2440/37737.

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Glass-ionomer cement has been used in the Atraumatic Restorative Technique (ART) for stabilisation of carious lesions. The infected layer or fully demineralised dentine is removed by dental hand instruments only and glass-ionomer cement is placed to restore the lesion leaving the affected layer or partly demineralised dentine underneath. There are many anecdotal and some published reports of the ability of these materials to remineralise partly demineralised dentine. The major objectives of this investigation are: 1. To scientifically demonstrate the ability of glass-ionomers to remineralise p
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Cenicante, João Pedro Alves Valadas de Lima. "The use of autogenous teeth for alveolar ridge preservation : a literature review." Master's thesis, 2021. http://hdl.handle.net/10400.26/38444.

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Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz<br>Following a tooth extraction, a cascade of biological events will lead inevitably to a decrease in the height and width of the alveolar ridge, mostly on the buccal side and horizontally. In this sense, given how often this procedure is performed in dental practice, it is pivotal that every clinician is acquainted with these dimensional changes and its possible impact on future oral rehabilitation. Consequently, several treatment modalities, commonly known as Alveolar Ridge Preservation (ARP) are described in
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Els, Frederick Andries. "Osteoinductivity of human demineralised bone matrix fortified with human donor-derived bone morphogenetic protein fraction." 2012. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001210.

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M. Tech. Biomedical Technology.<br>Aims to gain more insights into the effect of a specific human derived BMP-complex, standardised according to the human BMP-2 content, by loading it at concentrations higher than the concentration of the morphogen found in human (hDBM), in order to determine changes in the osteogenic response.
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Femia, Alexandra Lynn. "The comparative role of demineralized bone matrix placement on the periosteum versus in the muscle with and without bone morphogenetic protein 2." Thesis, 2015. https://hdl.handle.net/2144/16185.

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Demineralized bone matrix (DBM) is an allograft material used in orthopedics that promotes endochondral bone formation. While the placement of DBM on either the periosteal surface of a bone or within a skeletal muscle promotes the recruitment of stem cells that can form skeletal tissues through the temporal progression of endochondral bone development, it remains unclear to what degree these processes are different between the two sites. In this study, we utilize a comparative in vivo model of endochondral ossification by implanting the DBM on the periosteum and in the muscle. Within the muscl
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Tseng, Yueh Chin, and 曾樂琴. "Effects of Cyclosporine and Demineralized Bone Matrix Grafting on trabecular Bone Morphology at Maxillo-facial Bony Defects in Rats." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/39863507767121412808.

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碩士<br>國防醫學院<br>牙醫科學研究所<br>87<br>Demineralized freeze dried bone (DFDB) has been widely used for repairing the various osseous defects since bone induction potential from DFDB was first reported by Urist and his coworkers in 1965. Although factors affecting the success or failure of allo- or xeno-genic bone grafting have still not been fully understood, immune reactions obviously plays a certain important role. Cyclosporin A (CsA), an immunosuppressant, acts primarily on the inhibition of T cell activation. However, CsA can also modulate bone turnover. Documents investigating whether CsA ca
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Dodge, John R. "Improved bone regeneration and root coverage using Guidor resorbable membranes with physically assisted cell migration and demineralized bone allograft." 1998. http://catalog.hathitrust.org/api/volumes/oclc/48225556.html.

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Korsnes, Jeffrey N. "Effects of a demineralized bone matrix material on alveolar ridge preservation [a dissertation submitted in partial fulfillment for the degree of Master of Science in Periodontics] /." 2005. http://catalog.hathitrust.org/api/volumes/oclc/67878297.html.

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Verhagen, Connie May. "I̲n̲ v̲i̲v̲o̲ remineralization of demineralized bovine enamel a comparison study of 1000 ppm MFP and 1500 ppm MFP fluoride dentifrices : a thesis submitted in partial fulfillment ... pediatric dentistry /." 1988. http://catalog.hathitrust.org/api/volumes/oclc/68790442.html.

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MARINI, ROBERTA. "COMPARATIVE EVALUATION OF DEMINERALIZED BONE MATRIX AND HYDROXYAPATITE TRICALCIUM PHOSPHATE AS SCAFFOLDS FOR BONE REGENERATION WITH OR WITHOUT HUMAN MESENCHYMAL STEM CELLS:in vitro and in vivo preliminary results." Doctoral thesis, 2016. http://hdl.handle.net/11573/866147.

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