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Rozprawy doktorskie na temat „Deoxyribonucleic acid (DNA)”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Pope, Lisa Helen. "X-ray and neutron fibre diffraction studies of deoxyribonucleic acid." Thesis, Keele University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388355.

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Mallinder, Benjamin. "Detection of deoxyribonucleic acid by surface enhanced resonance Raman scattering spectroscopy (SERRS)." Thesis, University of Strathclyde, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248771.

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Bryson, Kevin. "Molecular simulation of DNA and its interaction with polyamines." Thesis, University of York, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297070.

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Walton-Williams, Laura. "An evaluation of the transfer and persistence of deoxyribonucleic acid (DNA) evidence." Thesis, Staffordshire University, 2016. http://eprints.staffs.ac.uk/2786/.

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DNA analysis is now a sufficiently sensitive technique to enable identification of an individual from an extremely small amount of biological material. Exhibits are routinely submitted to forensic laboratories for recovery and analysis of ‘touch DNA’, in order to link an offender to the crime scene. One such exhibit type is spent cartridge cases, where DNA transferred from the handler to the exterior surface of the casing may be the only evidence available for identification of the handler. Alternatively the firearm itself may be recovered, which could also have potential for uncovering the id

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5

Williams, Robert Keith. "Molecular conformational studies of deoxyribonucleic acid by potential energy minimization with normal mode analysis." Thesis, Keele University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292541.

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6

Edirisinghe, Pathirannehelage Neranjan S. "Charge Transfer in Deoxyribonucleic Acid (DNA): Static Disorder, Dynamic Fluctuations and Complex Kinetic." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/phy_astr_diss/45.

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The fact that loosely bonded DNA bases could tolerate large structural fluctuations, form a dissipative environment for a charge traveling through the DNA. Nonlinear stochastic nature of structural fluctuations facilitates rich charge dynamics in DNA. We study the complex charge dynamics by solving a nonlinear, stochastic, coupled system of differential equations. Charge transfer between donor and acceptor in DNA occurs via different mechanisms depending on the distance between donor and acceptor. It changes from tunneling regime to a polaron assisted hopping regime depending on the donor-acc

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7

Sefah, Kwame. "Development of deoxyribonucleic acid (DNA) aptamers as effective molecular probes for cancer study." [Gainesville, Fla.] : University of Florida, 2009. http://purl.fcla.edu/fcla/etd/UFE0041196.

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8

Yu, Zhou. "Optical Properties of Deoxyribonucleic Acid (DNA) and Its Application in Distributed Feedback (DFB) Laser Device Fabrication." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1154706431.

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9

Peters, Dimetrie Leslie. "Evaluation of eukaryotic cultured cells as a model to study extracellular DNA / D.L. Peters." Thesis, North-West University, 2011. http://hdl.handle.net/10394/6929.

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The diagnostic value of extracellular occurring DNA (eoDNA) is limited by our lack of understanding its biological function. eoDNA exists in a number of forms, namely vesicle bound DNA, histone/DNA complexes or nucleosomes and virtosomes. These forms of DNA can also be categorized under the terms circulating DNA, cell free DNA, free DNA and extracellular DNA. The DNA can be released by means of form–specific mechanisms and seem to be governed by cell cycle phases and apoptosis. Active release is supported by evidence of energy dependant release mechanisms and various immunological– and messeng

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10

Fehrman, Cory Emily Marie. "Fabrication of a Deoxyribonucleic Acid Polymer Ridge Waveguide Electro-Optic Modulator by Nanoimprint Lithography." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1398419640.

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Howard, Caroline. "The development of Deoxyribonucleic Acid (DNA) based methods for the identification and authentication of medicinal plant material." Thesis, De Montfort University, 2010. http://hdl.handle.net/2086/3972.

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Herbal medicines are growing in popularity in the Western world and are becoming more stringently regulated under new EU legislation. Within the arena of herbal medicines, St. John’s Wort (SJW), Hypericum perforatum, is a top ten best seller with clinical evidence to support its use as an anti-depressant. A fundamental requirement of the new legislation is to prove the identity of the plant material in question. This is currently achieved via morphological and chemical methods, neither of which are ideal. A wide range of DNA based methods have been applied to this arena, standardisation is req

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12

Frey, Jeffrey Daniel. "Finding Song Melody Similarities Using a DNA String Matching Algorithm." Kent State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=kent1208961242.

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13

Michelle, Burrows Adria. "A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting." University of the Western Cape, 2018. http://hdl.handle.net/11394/6489.

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Magister Scientiae - MSc (Biotechnology)<br>The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that was designed in a hierarchical manner according to the YSNP tree. This project mainly focused on African ancestry and was used to infer paternal ancestral lineages on the Johannesburg Coloured population. South Africa has a diverse population that has ancestral history from across the globe. The South African Coloured population i

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14

Bosman, Anna-Mari. "Detection of Babesia species in domestic and wild Southern African felids by means of DNA probes." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/23149.

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Feline babesiosis, first described in domestic cats in South Africa in 1937, is regarded to be of great importance in the coastal regions although isolated cases also occur on the eastern highlands of Mpumalanga Province. Babesia felis (described from domestic cats) and B. leo (described from lions) are the two best characterised Babesia species in felids. These two parasites are morphologically similar when examined under a light microscope, but are serologically and genetically distinct. In this study the prevalence of these two Babesia species in various wild and domestic felid species was

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15

Wood, Timothy Paul. "Identification of key mechanism in the cytotoxic effect of two novel anti-cancer compounds on breast cancer cells." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/24532.

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Organometallic chemotherapeutic agents, many of which target DNA, have been shown to be effective in the treatment of cancer. With that said though, these compounds have a number of side affects such as nephrotoxicity. Two novel compounds, Ferrocene [ferrocenoyltrichloroacetone] and Rhodium-ferrocene [(1.5 cyclooctadiene)(1-ferrocenyl- 4,4,4-trichloro-1,3-butanedionate], synthesised by the research group of J Swarts (University of the Free State) were evaluated to determine their mechanism of action and their potential use as novel therapeutic agents. It is hypothesized, by merit of their chem

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16

Brutzer, Hergen. "Mechanics and dynamics of twisted DNA." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-110154.

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Aufgrund einer komplexen Wechselwirkung mit Proteinen ist das Genom in einer Zelle ständig mechanischer Spannung und Torsion ausgesetzt. Daher ist es wichtig die Mechanik und die Dynamik von verdrillter DNA unter Spannung zu verstehen. Diese Situation wurde experimentell mittels einer sog. magnetischen Pinzette nachgestellt, indem sowohl Kraft als auch Drehmoment auf ein einzelnes DNA Molekül ausgeübt und gleichzeitig die mechanische Antwort des Polymers aufgezeichnet wurde. Als erstes Beispiel wurde der Übergang von linearer zu sog. plectonemischer DNA untersucht, d.h. die Absorption eines Te

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17

Akhtar, Mahmood Electrical Engineering &amp Telecommunications Faculty of Engineering UNSW. "Genomic sequence processing: gene finding in eukaryotes." Publisher:University of New South Wales. Electrical Engineering & Telecommunications, 2008. http://handle.unsw.edu.au/1959.4/40912.

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Of the many existing eukaryotic gene finding software programs, none are able to guarantee accurate identification of genomic protein coding regions and other biological signals central to pathway from DNA to the protein. Eukaryotic gene finding is difficult mainly due to noncontiguous and non-continuous nature of genes. Existing approaches are heavily dependent on the compositional statistics of the sequences they learn from and are not equally suitable for all types of sequences. This thesis firstly develops efficient digital signal processing-based methods for the identification of genomic

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SANTOS, Thiago Augusto Dias. "Detecção fotoeletroanalítica de adrenalina baseada em DNA e nanopartículas de TiO2 sensibilizadas com Bis (Etilenoditio) tetratiofulvaleno explorando luz de led." Universidade Federal do Maranhão, 2017. https://tedebc.ufma.br/jspui/handle/tede/tede/1950.

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Submitted by Rosivalda Pereira (mrs.pereira@ufma.br) on 2017-10-02T20:17:04Z No. of bitstreams: 1 ThiagoSantos.pdf: 1103502 bytes, checksum: 16ad7405a0ab31d83423293c43110ee8 (MD5)<br>Made available in DSpace on 2017-10-02T20:17:04Z (GMT). No. of bitstreams: 1 ThiagoSantos.pdf: 1103502 bytes, checksum: 16ad7405a0ab31d83423293c43110ee8 (MD5) Previous issue date: 2017-09-11<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão<br>Instituto Nacional de Ciência e Tecnologia em Bioanalítica<br>A pho

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19

Gault, Manon. "L’homéostasie des métaux chez la bactérie Escherichia coli : de l’analyse générale d’un stress sur l’expression des gènes, à la compréhension des mécanismes moléculaires." Thesis, Lyon, INSA, 2014. http://www.theses.fr/2014ISAL0130/document.

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Les métaux sont indispensables à la vie cellulaire car ils sont constitutifs des protéines. Les ions Ni, font partie intégrante des hydrogénases, enzymes primordiales pour le métabolisme énergétique. Paradoxalement, en excès, les métaux deviennent toxiques pour la cellule. Les bactéries luttent contre cette toxicité en produisant des systèmes de résistance ou d’adaptation. Les cellules procaryotes peuvent équilibrer les teneurs en métaux en contrôlant leur entrée ou leur efflux grâce à la biogenèse de transporteurs spécifiques. L’objectif de ces travaux de thèse a consisté à comprendre les méc

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20

Boote, Craig. "Structural studies of deoxyribonucleic acids using diffraction and spectroscopic methods." Thesis, Keele University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287969.

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21

Crawford, Margaret. "The regulation of meiotic recombination by DNA damage response proteins." Thesis, University of Sussex, 2017. http://sro.sussex.ac.uk/id/eprint/69964/.

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22

Kan, Yongzhi. "Probing the structural and electronic properties of deoxyribonucleic acids with anthraquinone photonucleases." Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/30475.

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23

Przybylski, Jennifer L., and University of Lethbridge Faculty of Arts and Science. "Computational modeling of the hydrolysis of 2'-deoxyribonucleic acids." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Chemistry and Biochemistry, c2009, 2009. http://hdl.handle.net/10133/1292.

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The mechanism for the hydrolysis of 2′-deoxyribonucleosides is examined using computational chemistry techniques. Initially, a model capable of accurately predicting the mechanism and activation barrier for the uncatalyzed hydrolysis of 2′-deoxyuridine is designed. It is found that the smallest model includes both explicit and implicit solvation during the optimization step. Next, this hybrid solvation model is applied to four natural nucleosides, namely 2′-deoxyadenosine, 2′-deoxycytidine, 2′-deoxyguanosine and thymidine. The hybrid model correctly predicts the trend in activation Gibbs energ

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24

Rutherford, Paul. "Usability of navigation tools in software for browsing genetic sequences." Diss., Lincoln University, 2008. http://hdl.handle.net/10182/948.

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Software to display and analyse DNA sequences is a crucial tool for bioinformatics research. The data of a DNA sequence has a relatively simple format but the length and sheer volume of data can create difficulties in navigation while maintaining overall context. This is one reason that current bioinformatics applications can be difficult to use. This research examines techniques for navigating through large single DNA sequences and their annotations. Navigation in DNA sequences is considered here in terms of the navigational activities: exploration, wayfinding and identifying objects. A proce

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25

Ptasińska, Katarzyna (Katie). "Studying DNA replication dynamics in Schizosaccharomyces pombe using next generation sequencing." Thesis, University of Sussex, 2018. http://sro.sussex.ac.uk/id/eprint/80884/.

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26

Avenas, Quentin. "Intégration d’une méthode d’actuation électrocinétique sur biocapteur plasmonique." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEI122/document.

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Cette thèse porte sur le développement d’un capteur plasmonique intégrant une fonction d’actuation des objets visés. L’objectif est de passer outre la limite de diffusion rencontrée à basse concentration en piégeant les particules sur la surface de détection. La stratégie adoptée est de structurer le film d’or servant à la détection de manière à pouvoir l’utiliser pour mettre en mouvement le fluide et les molécules par le biais de champs électriques. Le transfert de masse est réalisé par diélectrophorèse et électroosmose, deux effets électrocinétiques mis en oeuvre par des électrodes servant à

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27

Valle, Orero Jessica. "Dynamics and thermal behaviour of films of oriented DNA fibres investigated using neutron scattering and calorimetry techniques." Phd thesis, Ecole normale supérieure de lyon - ENS LYON, 2012. http://tel.archives-ouvertes.fr/tel-00734670.

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The majority of structural studies on DNA have been carried out using fibre diffraction, while studies of its dynamics and thermal behaviour have been mainly performed in solution. When the DNA double helix is heated, it exhibits local separation of the two strands that grow in size with temperature and lead to their complete separation. This work has investigated various aspects of this phenomenon. The experiments reported in this thesis were carried out on films of oriented fibres of DNA prepared with the Wet Spinning Apparatus. Thus, sample preparation and characterisation are essential par

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28

"Theoretical investigation of cisplatin-deoxyribonucleic acid crosslink products." 2004. http://library.cuhk.edu.hk/record=b5892233.

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Fu Annie Yuen Yee.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 97-108).<br>Abstracts in English and Chinese.<br>ABSTRACT (ENGLISH) --- p.iii<br>ABSTRACT (CHINESE) --- p.iv<br>ACKNOWLEDGMENTS --- p.v<br>TABLE OF CONTENTS --- p.vi<br>LIST OF FIGURES --- p.ix<br>LIST OF TABLES --- p.xi<br>Chapter CHAPTER ONE: --- BACKGROUND INFORMATION --- p.1<br>Chapter 1.1 --- Introduction --- p.1<br>Chapter 1.2 --- Deoxyribonucleic Acid --- p.1<br>Chapter 1.2.1 --- Nomenclature and Symbols --- p.1<br>Chapter 1.2.2 --- Torsion Angles ---

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Basu, Ruma. "Empirical Bayes, Bayes factors and deoxyribonucleic acid fingerprinting." Thesis, 2017. https://doi.org/10.7916/D8J67VGB.

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The central theme in this thesis is Empirical Bayes. It starts off with application of Bayes and Empirical Bayes methods to deoxyribonucleic acid fingerprinting. Different Bayes factors are obtained and an alternative Bayes factor using the method of Savage is studied both for normal and non- normal priors. It then moves on to deeper methodological aspects of Empirical Bayes theory. A 1983 conjecture by Carl Morris on the parametric empirical Bayes prediction intervals for the normal regression model is studied and an improvement suggested. Carlin and Louis’ (1996) parametric empirical Bayes p

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30

Wang, Jason James, and 王薪崴. "Influence of Proton Therapy on Brain Tumor Deoxyribonucleic Acid (DNA) and Dose Distribution Analysis." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/9we9u2.

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碩士<br>國立清華大學<br>動力機械工程學系<br>105<br>Brain cancer is a lethal disease which is quite difficult to cure by traditional therapy such as surgery since human brain consists of very complicated nervous system. It is very likely to make undesirable mistakes during an operation. Proton therapy is a very effective method to destroy brain cancer cells because it has a special characteristic: the Bragg Peak. This special feature allows the dose deposit in the premier part of the incident path to remain at a very low value and then suddenly soar to the climax. With this magnificent phenomenon, it is possib

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Harry, Lionel David. "A legal analysis of the study of the scientific evidence of Deoxyribonucleic Acid (DNA)." Diss., 2020. http://hdl.handle.net/10500/27883.

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This study analyses how DNA evidence can be distorted by the behaviour of criminal investigators and role-players within the Criminal Justice System (CJS). This has a negative impact on justice resulting in further criminality. The study has resulted in revelatory weaknesses owing to constitutional violations which cause sound evidence to become futile as it will not be admissible in court. Justice is aborted. The researcher has further explained the properties of the pertinent terms, such as: mental illness, psycho-social functioning, DNA, forensic investigator, forensic psychology, and court

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"Theoretical investigation of cisplatin-deoxyribonucleic acid crosslink products using hybrid molecular dynamics + quantum mechanics method." 2009. http://library.cuhk.edu.hk/record=b5893997.

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Yan, Changqing.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2009.<br>Includes bibliographical references (leaves 92-97).<br>Abstracts in English and Chinese.<br>ABSTRACT (ENGLISH) --- p.iii<br>ABSTRACT (CHINESE) --- p.iv<br>ACKNOWLEDGMENTS --- p.v<br>LIST OF ABBREVIATIONS --- p.vi<br>TABLE OF CONTENTS --- p.vii<br>LIST OF FIGURES --- p.ix<br>LIST OF TABLES --- p.x<br>Chapter CHAPTER ONE: --- BACKGROUND INFORMATION --- p.1<br>Chapter 1.1 --- Introduction --- p.1<br>Chapter 1.2 --- Deoxyribonucleic Acid --- p.2<br>Chapter 1.3 --- DNA Studies --- p.9<br>Chapter 1.4 --- Cispla

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33

Khan, Zainub. "Studies on the coupling of DNA to low density lipoproteins (LDL) and the interaction of these complexes with eukaryotic cells." Thesis, 1987. http://hdl.handle.net/10413/9700.

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The application of Molecular Biochemistry for transfection studies in eukaryotic systems is well documented. Of the numerous methods employed for the introduction of foreign DNA into eukaryotic cells, the use of low density lipoproteins (LDL) as carriers of DNA into cells has not been reported. LDL was isolated, characterized with respect to its protein and lipid components, and then variously modified in an attempt to enhance its affinity for DNA. It was found that both unmodified and modified LDL could interact with DNA, at physiological pH. The carbodiimide modified LDL (ECDI - LDL) showed

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Schriek, Cornelis Arnold. "Analysis and standardization of marker genotype data for DNA fingerprinting applications." Diss., 2011. http://hdl.handle.net/2263/28908.

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Genetic polymorphisms can be seen as the occurrence of more than one form of a DNA- or protein sequence at a single locus in a group of organisms, where these different forms occur more frequently than can be attributed to mutation alone. The combination of genetic polymorphisms present in the genome of a particular individual is referred to as its genotype. A wide range of genotyping techniques have been developed to detect and visualize genetic polymorphisms. One such technique examines highly polymorphic repetitive DNA regions called microsatellites, also called “short tandem repeats” (STRs

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35

Hawtrey, Richard William. "Studies on the preparation and interaction of modified transferrin-DNA complexes with HeLa cells." Thesis, 1986. http://hdl.handle.net/10413/10143.

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The correction of human genetic disorders by transfer of genetic material to cells is under intensive investigation in a number of 1aboratories. One possible way of trying to achieve the transfer of nucleic acid is by attaching DNA to a protein which has specific receptors on cells and which undergoes receptor-mediated endocytosis. In order to make use of the ligand protein-receptor approach for DNA transfer, iron-loaded human serum transferrin has been modified with the water soluble carbodiimides N-ethy1-N I -(3-dilllethy1aminopropyl) carbodiimide (CDI) and its quaterary analogue (ECDI) to g

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Krishnamurthy, Vinita. "Cofactor And DNA Interactions In The EcoPI DNA Methyltransferase." Thesis, 1996. https://etd.iisc.ac.in/handle/2005/1683.

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Krishnamurthy, Vinita. "Cofactor And DNA Interactions In The EcoPI DNA Methyltransferase." Thesis, 1996. http://etd.iisc.ernet.in/handle/2005/1683.

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Ramesh, V. "DNA Binding Studies With The Transcriptional Activator Protein C Of Bacteriophage MU." Thesis, 1995. https://etd.iisc.ac.in/handle/2005/1752.

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Ramesh, V. "DNA Binding Studies With The Transcriptional Activator Protein C Of Bacteriophage MU." Thesis, 1995. http://etd.iisc.ernet.in/handle/2005/1752.

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Weiler, Solly. "Synthesis of DNA - protein conjugates and a preliminary study of their interaction with eukaryotic cell receptors." Thesis, 1986. http://hdl.handle.net/10413/9973.

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Thymidine oligomers were chemically synthesised and linked to available amino functions of transferrin in alternative orientations: (a) A CMP residue attached to the 3' end of (pT)₁₀ with terminal deoxynucleotidyl transferase was oxidised with NaI0 and linked to transferrin via a Schiff base formation. (b) The 5' terminal phosphate group of (pT)₅ was activated with imidazole and reacted with transferrin to form a phosphoramide bond. The (pT)₅ thus attached to the protein was elongated to (pT)₃₀₀ using terminal deoxnucleotidyl transferase and TTP. The latter conjugate was capable of hybridising

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41

"Hepatitis B virus Deoxyribonucleic acid (HBV-DNA) in peripheral blood leukocytes of patients with different HBV-associated liver diseases." Chinese University of Hong Kong, 1991. http://library.cuhk.edu.hk/record=b5887061.

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by Lau Tze Chin, Gene.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1991.<br>Includes bibliographical references (Leaves 170-195).<br>Abstract --- p.1<br>Acknowledgement --- p.3<br>List of tables --- p.4<br>List of figures --- p.6<br>List of abbreviations --- p.7<br>Chapter Chapter One - --- Introduction --- p.9<br>Chapter 1.1. --- Historical Aspects --- p.9<br>Chapter 1.2. --- Classification of hepatitis B virus --- p.12<br>Chapter 1.2.1. --- Hepadnaviruses --- p.12<br>Chapter 1.2.2. --- Comparative properties of hepadnaviruses --- p.13<br>Chapter 1.2.2.1. --- Physical prop

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42

Jones, David Robert 1954. "Adenosine triphosphate (ATP) and deoxyribonucleic acid (DNA) content of marine microalgae and bacteria with applications for measuring marine microbial growth rates and production." Thesis, 1989. http://hdl.handle.net/10125/10023.

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Dywaba, Zukiswa Morencia. "An evaluation of the management of deoxyrinucleic acid (DNA) evidence." Diss., 2018. http://hdl.handle.net/10500/25210.

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DNA is identified as a powerful tool in the solving of rape cases, but it is often destroyed either by members of the public or the police officials who attend to the scene. The aim of the study was to evaluate the management of DNA evidence in rape cases in the Bishop Lavis Policing Area. To address the research topic under investigation, research questions, a legal framework and policies were used. The outcome of the study indicated poor performance in securing the crime scene and ensuring that physical evidence is preserved and not tampered with. On this basis, it was recommended that dev

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Brutzer, Hergen. "Mechanics and dynamics of twisted DNA." Doctoral thesis, 2012. https://tud.qucosa.de/id/qucosa%3A26816.

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Aufgrund einer komplexen Wechselwirkung mit Proteinen ist das Genom in einer Zelle ständig mechanischer Spannung und Torsion ausgesetzt. Daher ist es wichtig die Mechanik und die Dynamik von verdrillter DNA unter Spannung zu verstehen. Diese Situation wurde experimentell mittels einer sog. magnetischen Pinzette nachgestellt, indem sowohl Kraft als auch Drehmoment auf ein einzelnes DNA Molekül ausgeübt und gleichzeitig die mechanische Antwort des Polymers aufgezeichnet wurde. Als erstes Beispiel wurde der Übergang von linearer zu sog. plectonemischer DNA untersucht, d.h. die Absorption eines T

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Radko, Aleksandra. "Właściwości fizyczne i samoorganizacja kompleksów DNA-surfaktant kationowy : wpływ rodzaju DNA oraz struktury surfaktantu." Praca doktorska, 2022. https://ruj.uj.edu.pl/xmlui/handle/item/289765.

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Zablocki, Fabien Bernard Roman. "Multiple sequence alignment using particle swarm optimization." Diss., 2008. http://hdl.handle.net/2263/23406.

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The recent advent of bioinformatics has given rise to the central and recurrent problem of optimally aligning biological sequences. Many techniques have been proposed in an attempt to solve this complex problem with varying degrees of success. This thesis investigates the application of a computational intelligence technique known as particle swarm optimization (PSO) to the multiple sequence alignment (MSA) problem. Firstly, the performance of the standard PSO (S-PSO) and its characteristics are fully analyzed. Secondly, a scalability study is conducted that aims at expanding the S-PSO’s appli

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(9787022), Choudhury Wahid. "Microarray gene selection for cancer classification using support vector machine." Thesis, 2011. https://figshare.com/articles/thesis/Microarray_gene_selection_for_cancer_classification_using_support_vector_machine/13457105.

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Genes comprised of DNA (Deoxyribonucleic Acid) molecules contain the blueprint of any living organism. Expression levels of genes are the measures of genes activity under certain biochemical conditions. DNA microarray technology is widely used to measure gene expression levels and study gene interactions. This technology provides access to thousands of genes at once by recording expression levels simultaneously. The data generated by microarray technology is important because it has been shown that from gene expression changes we are able to extract different types of cancer information. Suppo

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Krejčová, Zuzana. "Voltametrické studium interakce genotoxického 2-nitrofluorenu s DNA na visící rtuťové kapkové elektrodě." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-297579.

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In this Diploma Thesis, an interaction of genotoxic environmental pollutant 2-nitrofluorene with a double-stranded calf thymus DNA has been studied using a hanging mercury drop electrode (HMDE) as an electrochemical sensor. Two types of DNA damage were investigated and electrochemically detected (using cyclic voltammetry and differential pulse voltammetry): (i) The DNA damage caused by the direct interaction with 2-nitrofluorene and (ii) the DNA damage caused by short-lived radicals generated by the electrochemical reduction of the nitro group in 2-nitrofluorene. For the study of direct intera

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"Random coil phosphorus chemical shift of deoxyribonucleic acids." 2004. http://library.cuhk.edu.hk/record=b5896196.

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Ho Cheuk-nang.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 89-94).<br>Abstracts in English and Chinese.<br>Acknowledge --- p.ii<br>Table of Contents --- p.iii<br>Lists of Tables --- p.vi<br>Lists of Figures --- p.vii<br>Abstract (English Version) --- p.x<br>Abstract (Chinese Version) --- p.xii<br>Chapter 1. --- Literature Survey of Phosphorus Chemical Shift Studies of DNA --- p.1<br>Chapter 1.1 --- Introduction --- p.1<br>Chapter 1.2 --- General Review of DNA Structures --- p.2<br>Chapter 1.2.1 --- "Nomenclature, Symbols a

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"Effect of 3-methylthymine on solution structures and thermodynamic stabilities of double-helical deoxyribonucleic acids." 2011. http://library.cuhk.edu.hk/record=b5894763.

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Zhong, Yangliu.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 50-57).<br>Abstracts in English and Chinese.<br>Title Page --- p.i<br>Thesis Committee --- p.ii<br>Abstract (English Version) --- p.iv<br>Abstract (Chinese Version) --- p.V<br>Acknowledgement --- p.vi<br>Table of Contents --- p.viii<br>List of Tables --- p.X<br>List of Figures --- p.xii<br>List of Abbreviations and Symbols --- p.xiii<br>Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- DNA methylation --- p.1<br>Chapter 1.2 --- Repair of m3T --- p.2<br>Chap

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