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Rozprawy doktorskie na temat „Diabetes – Complications”

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Data publikacji: 4 czerwca 2021
Data aktualizacji: 25 lipca 2025

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1

Nordwall, Maria. "Long term complications in juvenile diabetes mellitus." Doctoral thesis, Linköping : Univ, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-6377.

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2

Choudhury, Maitrayee. "Complications in cystic fibrosis-related diabetes." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/100648/.

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Cystic fibrosis-related diabetes (CFRD) is a secondary form of diabetes, associated with increasing age in subjects with Cystic Fibrosis (CF). With improved life expectancy, CFRD is anticipated to increase in prevalence in addition to its complications. The aim of this study was to investigate the use of HbA1c as an early predictor of disease, as well as investigate microvascular and macrovascular complications in an adult CF cohort attending the All Wales Cystic Fibrosis Centre. The current method of using the conventional oral glucose tolerance test (OGTT) to diagnose CFRD was compared to us
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3

Wu, Di. "Discovery of glyco-biomarkers for diabetes and complications in diabetes." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/e2eee4c8-c74c-4fc6-8658-ab51ecd793de.

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Diabetes mellitus is a group of metabolic diseases characterized in disordered blood glucose levels with many altered genes, proteins and metabolites. The chronic hyperglycemia in diabetes damages organ systems and makes the diabetic patients vulnerable to one or more complications. The onset of diabetes and complications in diabetes are estimated to occur 5 to 10 years before the clinical diagnosis. The early diagnosis of diabetes prevents the damage and pathological progress of diabetes and complications in diabetes. The central hypothesis of this study was that the protein N-glycosylation p
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4

Okafor, Eugene O. "Decreasing Acute Diabetes Complications Through Self-Management Education." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5922.

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Diabetes mellitus is a chronic disease that affects millions of people in the United States. The purpose of this project was to develop a guideline to help clinical staff provide clear and concise diabetes self-management instructions to patients in a community setting. Orem's self-care deficit theory (SCD) and health belief model (HBM) provided a platform to assess how patients' self-care deficit contributes to illness and the effect of patients' perception of illness. SCD theory and the HBM provided the framework for the development of the guideline to decrease diabetes acute complications t
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5

Yu, Zhen. "Altered drug responses in diabetic and hypertensive-diabetic cardiomyopathy." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29406.

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Diabetes mellitus has been associated with both clinical and experimental cardiac dysfunction. Diabetic cardiomyopathy which is characterized by depressed cardiac contractility is accompanied by a variety of biochemical changes in Ca⁺⁺ metabolism. This cardiomyopathy may occur in the presence of normal coronary arteries and normal blood pressure. However, some studies have shown that hypertension is more prevalent among diabetics and can aggravate the cardiovascular abnormalities associated with diabetes. To understand the mechanisms of diabetic cardiomyopathy and consequences of combined hype
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6

Bunker, Richard David. "Enzymes associated with the complications of diabetes mellitus." Thesis, University of Auckland, 2010. http://hdl.handle.net/2292/7142.

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Diabetes mellitus (DM) is a metabolic disease resulting from failures in the production or response to the hormone insulin. Much of the pathogenesis and mortality attributed to DM are due to the long-term complications of hyperglycaemia, which is characteristic of the disease. This thesis presents structural and functional studies of two previously uncharacterised human enzymes, dihydrodipicolinate synthase-like protein (DHDPSL) and D-xylulokinase (XK). Both enzymes were revealed to have unexplored associations with DM. DHDPSL is distantly related (~25% sequence identity) to a family of Schiff
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7

Morgan, Eileen. "Type 1 diabetes - epidemiology, risk factors and complications." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678213.

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This thesis examined the incidence and temporal trends of Type 1 diabetes diagnosed in Northern Ireland children using data from the Northern Ireland Childhood Diabetes Register (NICDR). Overall, there was evidence of a departure from linearity in incidence with indications that rates are levelling off in recent years. Further analyses also indicated that birth cohort effects were evident in the incidence rates suggesting that exposures in early life may play an aetiological role in this condition. A systematic review and meta-analyses was performed in this thesis to investigate the associatio
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8

Naito, Masaki. "Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice." Kyoto University, 2012. http://hdl.handle.net/2433/157453.

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9

Cross, Deborah F. "Genetic analysis of the microvascular complications of diabetes mellitus." Thesis, University of Plymouth, 2002. http://hdl.handle.net/10026.1/2316.

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There is increasing evidence to suggest that genetic factors are involved in the pathogenesis of microvascular complications in diabetes mellitus. Recent studies have suggested that genetic variations in the aldose reductase (ALR2) gene may contribute to the genetic susceptibility to microvascular complications. Aldose reductase is the first and rate-limiting enzyme of the polyol pathway and is implicated in the pathogenesis of diabetic microvascular disease (nephropathy, retinopathy and neuropathy). It has recently been shown that the three polymorphisms of the ALR2 gene are associated with s
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10

Cho, Chi Shing. "Proteomic and medicinal approaches to diabetes and its complications." HKBU Institutional Repository, 2006. http://repository.hkbu.edu.hk/etd_ra/663.

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11

Ochieng, Judith Muhonja. "Risk Perception of Developing Diabetes Complications among African American Women with Type 2 Diabetes." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/577503.

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Background: African American (AA) women have a disproportionately higher prevalence of Type 2 Diabetes Mellitus (T2DM) and its related complications than Hispanics and non-Hispanic white women. Cultural practices, stigmatization, discrimination, socio-economic status, historical experiences and geographical locations have all been proposed as factors that influence the prevalence of T2DM in AA women. However, no study has explored how AA women with T2DM perceive their risk of developing diabetes complications, and how their risk perceptions impact their diabetes self -management. Purpose: The
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12

Lian, Jinxiao, and 連金曉. "A review of cost-effectiveness analysis of screening for diabetic complication." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42997240.

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13

Vindedzis, Sally Ann. "The relationship between low blood thiamin levels in diabetes to thiamin intake and diabetic control." Thesis, Curtin University, 2008. http://hdl.handle.net/20.500.11937/248.

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Mild thiamin deficiency is prevalent in diabetes, and high dose thiamin ameliorates some diabetic complications, but there are no definitive studies addressing thiamin intake, diabetes control and thiamin status in diabetes. Subjects were 113 people with diabetes (58 type 1, 55 type 2), 43 with and 70 without thiamin supplementation. Dietary thiamin was estimated by 24-hour recall, diabetes control by HbA1c. Age, BMI, albumin excretion, activity level and smoking status did not correlate with red cell thiamin (RCT) in either group. RCT correlated with serum thiamin (ST) (p < 0.01). In those un
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14

Moffett, Henley Jasmine. "A Descriptive Analysis of Diabetic Complications and Antihypertensive Use Among Pima Indians." The University of Arizona, 2007. http://hdl.handle.net/10150/624406.

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Class of 2007 Abstract<br>Objectives: To determine the effect of antihypertensive use on renal function and other diabetic complications in adults over the age of 18 with type 2 diabetes mellitus (DM). Methods: A retrospective secondary analysis of the NIH Pima epidemiologic data included 1,828 individuals with type 2 DM were evaluated for antihypertensive use and DM complications. Statistical analysis was done using general linear model regression (GLM) or logistic regression models controlling for age, sex and DM duration. Three groups were established to evaluate antihypertensive use Group
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15

McLaine, Catherine Clare. "Diabetes and oral health complications: Australian diabetes health care professionals' knowledge and scope of practice." Thesis, Curtin University, 2013. http://hdl.handle.net/20.500.11937/2373.

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The research investigated Australian diabetes health professionals’ (DHPs’) knowledge and their intervention, health promotion, and care management of oral health issues which impact upon the person with diabetes. Results identified the need for enhanced provision of diabetes-specific oral health education, clinical resource tools, and the delivery of oral health services. The findings were discussed within the context of the current health system policies and their impact upon DHPs’ management of diabetes related oral health complications.
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16

Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy." Thesis, The University of Sydney, 2005. http://hdl.handle.net/2123/1421.

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OBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complications in 2000 (cases), to
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17

Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy." University of Sydney, 2005. http://hdl.handle.net/2123/1421.

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Master of Public Health<br>OBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complic
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18

Caracciolo, Dana Andriana. "Children's Literature and Diabetes." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/31824.

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My studies consider the genre of children's literature, specifically picture books, and their treatment of the topic of diabetes. I frame my argument with an examination of diabetes, the psychological effects of diabetes on the child, the need of thorough education about diabetes. I argue for the use of the picture book as an effect tool in educating and socializing the diabetic child. I first explore the implications of diabetes and the long term complications caused by one's poor control of the disease. I then explore the psychological ramifications of a chronic illness on the young child
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19

Östlund, Ingrid. "Aspects of Gestational Diabetes : Screening System, Maternal and Fetal Complications." Doctoral thesis, Uppsala University, Department of Women's and Children's Health, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3267.

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<p>The appropriateness of universal screening for gestational diabetes mellitus (GDM) has been strongly questioned, since it does not satisfy ethical principles for screening. </p><p> The aims of these studies were to determine the prevalence of GDM, expressed in terms of impaired glucose tolerance (IGT) and diabetes mellitus (DM), to evaluate different screening models using traditional anamnestic risk factors and repeated random B-glucose, to determine whether GDM increases risks for maternal complications such as preeclampsia, and to determine whether IGT during pregnancy, if left untrea
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20

Tossavainen, née Riihimaa P. (Päivi). "Markers of microvascular complications in adolescents with type 1 diabetes." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:951426892X.

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Abstract The markers of microvascular complications of type 1 diabetes were evaluated in adolescents in a cross sectional survey of 100 out of 138 eligible patients aged 9-19 years with a duration of diabetes over two years who visited the Paediatric Outpatient Clinic at Oulu University Hospital in 1997-1999, and one hundred healthy controls. Two patients in early or mid-puberty had non-proliferative diabetic retinopathy, but no other signs of microvascular complications. The five patients with persistent microalbuminuria were all girls; one prepubertal, one late pubertal and three postpube
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21

Lyons, Paul Anthony. "The erythrocyte polyol pathway, diabetes and its long term complications." Thesis, Imperial College London, 1990. http://hdl.handle.net/10044/1/46419.

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22

Ajudua, Emmanuel Enuagwuna. "Profile of diabetic complications amongst diabetics attending internal medicine outpatient department and family medicine outpatient department in Dora Nginza Hospital, PE hospital complex." Thesis, Stellenbosch : University of Stellenbosch, 2015. http://hdl.handle.net/10019.1/97196.

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Thesis (MFamMed)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Introduction: Diabetes is the most prevalent endocrinology problem encountered in primary care practice. If recent trends showing a dramatic increase in prevalence (believed to be a consequence of a decline in physical activity and excessive caloric intake) continue, then the condition will soon affect nearly 20 million people in the U.S a reflection of the global trend. Effective management requires care that is thoughtful and meticulous, incorporating intensive patient education. Euglycemic control, with the level of glyco
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23

Ikombele, Botomwito. "Knowledge, attitudes and practices regarding lifestyle modifications among type 2 diabetic patients attending Mamelodi Hospital, Pretoria, South Africa." Thesis, University of Limpopo (Medunsa Campus), 2011. http://hdl.handle.net/10386/699.

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Thesis (M Med (Family Medicine) -- University of Limpopo, 2011.<br>Introduction The burden of type 2 diabetes mellitus continues to rise and constitutes a real threat especially in the developing world. As for most non-communicable diseases, change of behavior and adoption of healthy lifestyle habits help to prevent and slow down the increase of type 2 diabetes mellitus. Aim of the Study To establish the knowledge, attitudes and practices regarding lifestyle modifications among type 2 diabetic patients attending the diabetic clinic at Mamelodi hospital.
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24

Rodrigues, Brian Baltzar. "Hypertension and diabetic cardiomyopathy." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24906.

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The isolated perfused working heart was used to study hypertensive- diabetes induced alterations in cardiac function at 6 and 12 weeks after the induction of diabetes. There was no difference in cardiac function between normotensive Wistar and spontaneously hypertensive (SHR) diabetic rats at 6 weeks after diabetes induction. Wistar-Kyoto (WKY) rats were also included as normotensive controls in our 12-week study. Successful induction of diabetes was confirmed by the presence of hyperglycemia, hypoinsulinemia, glycosuria and increased haemoglobin glycosylation in all three diabetic groups. Ho
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25

Trifoglio, Emanuele. "Multi-level modeling and computational approaches to investigate long-term diabetes complications." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3424554.

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Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Worldwide prevalence figures estimate that there are 250 million diabetic patients today and that this number will increase by 50% by 2025. The disease is associated with devastating chronic complications including coronary heart disease, stroke and peripheral vascular disease (macrovascular disease) as well as microvascular disorders, leading to damage of kidneys (nephropathy) and eyes (retinopathy). These complications impose an immense burden on the quality of life of the patients and account for more than 10
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26

Leksell, Janeth. "Diabetes-related blindness : studies of self-management, power, empowerment and health /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6262.

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27

Lee, Kwanming. "Investigation on the correlation between methylglyoxal and diabetic complications : neurodegeneration and Osteoporosis." HKBU Institutional Repository, 2018. https://repository.hkbu.edu.hk/etd_oa/589.

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Diabetes Mellitus is a chronic disease characterized by uncontrollable chronic high blood glucose (hyperglycemia) and complications, leading to serious damage to different tissues. In clinical studies, diabetic patients are found to have a higher risk of developing neurodegeneration and osteoporosis, and hyperglycemia-induced formation of advanced glycation endproducts (AGEs) may contribute towards the pathogenesis of diabetes-induced neurodegeneration and osteoporosis. Therefore the aim of this project is to investigate the role of hyperglycemia-induced methylglyoxal (MG) on neurodegeneration
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28

Lo, Che Sam, and mikewood@deakin edu au. "Relationship of nutritional and metabolic factors to non-invasive, indices of macrovascular disease in diabetes." Deakin University. School of Sciences, 1986. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051208.122550.

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Factors which may account for the high frequency of macrovascular disease in diabetics are age, sex, cigarette smoking, hypertension, obesity, lack of exercise, diet, hyperglycaemia, hyperinsulinaeroia, hypercholesterolaemia, hypertriglyceridaemia, low HDL-cholesterol concentration, elevated free fatty acid concentration and enhanced platelet aggregation. Twenty seven (13 men and 14 women) non-insulin-dependent diabetics and thirty eight age, height and weight matched healthy subjects (10 men and 28 women) were studied. None of the subjects were smokers, or hypertensive. No subject had any cli
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29

Schenk, Johannes. "Examination of cardiovascular function in conscious hypertensive diabetic rats." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30318.

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This investigation was concerned with measuring aspects of cardiac function in conscious control, diabetic, hypertensive control, and hypertensive diabetic rats. Preliminary studies were conducted to determine catheter suitability and acute responses to atropine and angiotensin II in conscious animals. The catheter-manometer was tested using a square wave impact and was shown to accurately reproduce a left ventricular pressure pulse. Intravenous atropine caused both heart rate and left ventricular +dP/dt to rise. Intravenously administered angiotensin II caused systolic blood pressure to incr
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30

Gin, Teck Ong Leslie. "The attenuation of chronic complications in experimental diabetes by l-arginine /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17871.pdf.

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31

Чернацька, Ольга Миколаївна, Ольга Николаевна Чернацкая, Olha Mykolaivna Chernatska, et al. "Cardiovascular complications markers in hypertensive patients with type 2 diabetes mellitus." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/55026.

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The increase of blood pressure (BP) is the main risk factor of cardiovascular complications (CVC) for patients with type 2 diabetes mellitus (DM). There are also other markers of these complications such as glycated hemoglobin (HbA1с), dyslipidemia, characterized by atherogenic index (AI). The aim of our study was the determination of connection between markers of cardiovascular complications (CVC) for patients with type 2 DM and AH.
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32

Cleary, Liam. "HbA1c Test’s Accuracy as a Predictor for Diabetes with Complications Diagnosis: Further Analysis of the HbA1c Diabetes Mellitus Test." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:108925.

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Thesis advisor: Samuel Richardson<br>HbA1c levels are the most frequently used test for diagnosis and prognosis of diabetes mellitus. Recent studies have shown the biases this test has in particular cohorts, that was not noted when it was originally accepted by the American Diabetes Association in 2008. This study examined how these biases affect HbA1c’s ability as a predictor for complications that arise due to diabetes in specific cohorts, those of ethnicity, age, weight, and other patient attributes, compared to other established diabetes prognosis tests. We discovered that both glucose and
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33

Wong, Ching-keung, and 黃靜強. "The effects of streptozotocin-diabetes on adrenomedullin gene expression and peptide levels in the gastrointestinal system of therat." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45011503.

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34

Adegbola, Saheed Adekunle. "Assessment of the level of adherence to treatment among type 2 diabetic patients in Matlala District Hospital." Thesis, University of Limpopo ( Medunsa Campus ), 2010. http://hdl.handle.net/10386/414.

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Thesis (M Med (Family Medicine))--University of Limpopo, 2010.<br>The number of diabetic patients will continue to rise even in rural settings and the burden of this disease will continue to take its effect on the limited resources of these communities. The effect of such burden will be more pronounced if we are to add the various complications associated with substandard management of diabetes mellitus. The first step in assessing the level of care we give to this category of patients is to measure their level of adherence, in an effort to expose the pitfalls on both the side of the patients
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35

Vindedzis, Sally Ann. "The relationship between low blood thiamin levels in diabetes to thiamin intake and diabetic control." Curtin University of Technology, School of Public Health, 2008. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=118316.

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Mild thiamin deficiency is prevalent in diabetes, and high dose thiamin ameliorates some diabetic complications, but there are no definitive studies addressing thiamin intake, diabetes control and thiamin status in diabetes. Subjects were 113 people with diabetes (58 type 1, 55 type 2), 43 with and 70 without thiamin supplementation. Dietary thiamin was estimated by 24-hour recall, diabetes control by HbA1c. Age, BMI, albumin excretion, activity level and smoking status did not correlate with red cell thiamin (RCT) in either group. RCT correlated with serum thiamin (ST) (p < 0.01). In those un
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36

Alabi, Toyin Dorcas. "Effect of anchomanes difformis extract on biochemical and histological parameters in streptozotocin-induced diabetes and diabetic complications." Thesis, Cape Peninsula University of Technology, 2019. http://hdl.handle.net/20.500.11838/3074.

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Thesis (DPhil (Biomedical Sciences))--Cape Peninsula University of Technology, 2019<br>Diabetes mellitus is one of the major health challenges facing the world today and it is not restricted by age, gender, education or urbanisation. Increased oxidative stress, inflammation and apoptosis are implicated in the pathogenesis of diabetes mellitus. The progression of diabetes mellitus leads to pathological events and alterations in many tissues of the body, thereby causing damage to these tissues and organs. Anchomanes difformis is has a strong ethnopharmacological relevance and it is known for its
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37

Yan, Yu North Kari E. "Diabetes susceptibility polymorphisms and risk of prediabetes and diabetes complications in the Atherosclerosis Risk in Communities ARIC study." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2456.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Sep. 3, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the School of Public Health Epidemiology." Discipline: Epidemiology; Department/School: Public Health.
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38

Berhan, Yonas. "Epidemiological studies of childhood diabetes and important health complications to the disease." Doctoral thesis, Umeå universitet, Pediatrik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-85248.

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Background and aims: The overall aim of this thesis was to increase knowledge regarding the occurrence of childhood onset T1D and T2D in Sweden and in relation to that describe and elucidate important aspects on two grave complications to diabetes; end-stage renal disease (ESRD) and mortality. The two first studies included in this thesis aimed to describe and analyze the cumulative incidence of childhood onset T1D in Sweden and to assess the occurrence of undetected T2D in Swedish children. The aim with the third study was to describe the cumulative incidence of ESRD, and to analyze how ESRD
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39

Ingberg, Claes-Mårten. "Type 1 diabetes mellitus: Aspects of long-term complications and body composition." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3287.

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<p>Studies concerning social consequences, gastrointestinal and urinary tract symptoms were conducted in a population-based cohort comprising patients with long-standing type 1 diabetes and matched control persons. Three different questionnaires were sent by mail to diabetic patients and control persons. After a mean duration of 28.7±2.6 years, compared to the controls the diabetic patients showed an almost 10 times higher mortality, a lower employment rate and greater need for welfare benefits. These differences were mainly due to diabetic late complications. Education, housing conditions, li
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40

Ahmed, Ijaz. "Effects of Momordica charantia fruit juice on experimental diabetes and its complications." Thesis, University of Central Lancashire, 1999. http://clok.uclan.ac.uk/20106/.

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Momordica charantia fruit is traditionally used as a vegetable in the Indian subcontinent and is claimed to have hypoglycaemic effects in human and experimental diabetes. The oral administration of M. charantia fruit juice was investigated for its effects in streptozotocin (STZ)-induced diabetes in rats. The results of this study have revealed that the fruit juice administration reduced the blood glucose levels, improved glucose tolerance and increased blood insulin levels and body weights in STZ-induced diabetes in rats. However, the treatment of fruit juice did not completely normalize these
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41

Robertson, Douglas Paul. "Oral complications of Type 1 diabetes mellitus in a non-smoking population." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/3009/.

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Type 1 diabetes mellitus (T1DM) is a complex metabolic condition that results in hyperglycemia due to insulin deficiency (Daneman, 2006). Diabetes has a range of effects on almost every system in the body including the kidneys, the eyes, the cardiovascular system, the genito-urinary system, the gastro-intestinal system and the nervous system (Daneman, 2006). The effects of this ondition are widespread and have a significant impact both on life expectancy and the quality of life of individuals suffering from diabetes (Scottish Diabetes Survey Monitoring Group, 2011). The impact of diabetes on o
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42

Inyang, Cornelia E. "Patients' Perceptions of Diet-Only Therapy in the Prevention of Diabetes Complications." Thesis, Walden University, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13807269.

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<p> Type 2 diabetes is a chronic metabolic disorder and the seventh leading cause of death in the United States. Type 2 diabetes is linked to many chronic diseases, including cardiovascular disease, stroke, and chronic kidney failure. African American adults have a high prevalence of Type 2 diabetes with early onset of diabetes complications. Poor dietary behavior is the primary cause of Type 2 diabetes and its complications, changing dietary behaviors can prevent the onset of diabetes complications or impede existing ones. The purpose of this phenomenological study was to explore patients&rsq
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Inyang, Cornelia Emmanuel. "Patients' Perceptions of Diet-Only Therapy in the Prevention of Diabetes Complications." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6588.

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Type 2 diabetes is a chronic metabolic disorder and the seventh leading cause of death in the United States. Type 2 diabetes is linked to many chronic diseases, including cardiovascular disease, stroke, and chronic kidney failure. African American adults have a high prevalence of Type 2 diabetes with early onset of diabetes complications. Poor dietary behavior is the primary cause of Type 2 diabetes and its complications, changing dietary behaviors can prevent the onset of diabetes complications or impede existing ones. The purpose of this phenomenological study was to explore patients' percep
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Vulesevic, Branka. "Endothelium and Cardiovascular Complications of Diabetes Mellitus: the Role of the Glyoxalase System." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/33159.

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In patients with diabetes, hyperglycemia leads to functional impairment of endothelial cells (ECs) and microangiopathy. Inflammation and endothelial dysfunction (ED) have been associated with the development of several cardiovascular complications. Concentration of methylglyoxal (MG) - a highly reactive aldehyde is increased in diabetes. In a non-pathological state, MG is detoxified by the enzymes glyoxalase-1 (GLO1) and glyoxalase 2 in presence of glutathione. This thesis examines the role of MG accumulation in ECs and bone marrow cells (BMCs), with the consequences it has for their functio
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Duffy, Seamus. "Investigating genetic, epigenetic and biological ageing mechanisms in complications of type 1 diabetes." Thesis, Queen's University Belfast, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725835.

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This PhD project aimed to investigate the underlying genetic component of complications secondary to diabetes. This was accomplished by the combination of novel and emerging genetic technologies as well as bioinformatic approaches to probe the genome of multiple populations to determine the role of genetics in diabetic complications, specifically diabetic kidney disease and coronary artery disease. Additionally, I have had a long-standing interest in the functions of telomeres in human biology. I was fortunate to have the opportunity to incorporate this interest into this PhD thesis. Chapter 3
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Giardina, Marisol. "Knowledge-based supervised learning models for the assessment of type 2 diabetes complications." Thesis, University of Ulster, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446252.

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Rahman, Mushtaqur. "Evaluation of the effects of screening on the development of complications of diabetes." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613270.

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Rice, Ellen. "The impact of treatment and screening for diabetes complications on emergency department use." CONNECT TO ELECTRONIC THESIS, 2008. http://hdl.handle.net/1961/6863.

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Savu, Octavian. "Mechanisms of chronic complications of diabetes with focus on mitochondria and oxygen sensing." Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-764-1/.

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Constantino, Maria Ines. "The Utility of Electronic Health Records: A Study of diabetes and its complications." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21211.

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Type 2 diabetes is a heterogeneous condition, but evidence gaps exist with respect to risks and outcomes for sub-populations. The tenet of this thesis is that routinely collected clinical data captured within the eHR can be utilised for diabetes research; the eHR can provide new information with specific regard to further characterising diabetes sub-populations, which can meaningfully inform patient care. Clinical data captured in the course of usual patient care for over 20,000 patients held within the longstanding RPAH Diabetes Centre eMR was studied. Data linkage was undertaken with the Nat
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