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Rozprawy doktorskie na temat „DNA microarrays”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Stephens, Nathan W. "A comparison of genetic microarray analyses : a mixed models approach versus the significance analysis of microarrays /." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1604.pdf.

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Brunner, Thomas. "Designing oligonucleotides for DNA microarrays /." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, Department of Computer Science, 2003. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=116.

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3

Smith, Kaleigh. "Towards quality control in DNA microarrays." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79129.

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We present a framework for detecting degenerate probes in a DNA microarray that may add to measurement error in hybridization experiments. We consider four types of behaviour: secondary structure formation, self-dimerization, cross-hybridization and dimerization. The framework uses a well-established model of nucleic acid sequence hybridization and a novel method for the detection of patterns in hybridization experiment data. Our primary result is the identification of unique patterns in hybridization experiment data that are correlated with each type of degenerate probe behaviour. The

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4

Arrais, Joel Perdiz. "Sistemas de informação para DNA microarrays." Doctoral thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/2232.

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Doutoramento em Engenharia Informática<br>O projecto de sequenciação do genoma humano veio abrir caminho para o surgimento de novas áreas transdisciplinares de investigação, como a biologia computacional, a bioinformática e a bioestatística. Um dos resultados emergentes desde advento foi a tecnologia de DNA microarrays, que permite o estudo do perfil da expressão de milhares de genes, quando sujeitos a perturbações externas. Apesar de ser uma tecnologia relativamente consolidada, continua a apresentar um conjunto vasto de desafios, nomeadamente do ponto de vista computacional e dos sistemas de

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5

Harness, Denise. "A Comparison of Unsupervised Methods for DNA Microarray Leukemia Data." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/106.

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Advancements in DNA microarray data sequencing have created the need for sophisticated machine learning algorithms and feature selection methods. Probabilistic graphical models, in particular, have been used to identify whether microarrays or genes cluster together in groups of individuals having a similar diagnosis. These clusters of genes are informative, but can be misleading when every gene is used in the calculation. First feature reduction techniques are explored, however the size and nature of the data prevents traditional techniques from working efficiently. Our method is to use the pa

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6

Chow, Brian 1978. "Photoelectromechanical synthesis of low-cost DNA microarrays." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/42405.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2008.<br>Includes bibliographical references.<br>Recent advances in de novo gene synthesis, library construction, and genomic selection for target sequencing using DNA from custom microarrays have demonstrated that microarrays can effectively be used as the world's cheapest sources of complex oligonucleotide pools. Unfortunately, commercial custom microarrays are expensive and not easily accessible to academic researchers, and technical challenges still exist for dea

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7

Horschinek, Andreas. "DNA-Microarrays zur therapiebegleitenden Prognose bei Brustkrebs." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-27654.

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8

Xue, Mei. "Array based integrated DNA identification system for genetic chip application /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?ELEC%202002%20XUE.

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9

Peeters, Justine Kate. "Microarray bioinformatics and applications in oncology." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/12618.

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10

Karanam, Suresh Kumar. "Automation of comparative genomic promoter analysis of DNA microarray datasets." Thesis, Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-04062004-164658/unrestricted/karanam%5Fsuresh%5Fk%5F200312%5Fms.pdf.

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11

Goh, Liang. "Computational methods for microarray gene expression analysis through integration and knowledge discovery a thesis submitted to Auckland University of Technology in partial fulfillment of the degree of Doctor of Philosophy, 2005." Full thesis. Abstract, 2005. http://puka2.aut.ac.nz/ait/theses/GohL.pdf.

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12

Leung, Yuk-yee. "An integrated framework for feature selection and classification in microarray data analysis." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43278632.

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13

Farcomeni, Alessio. "Multiple testing procedures under dependence, with applications." Doctoral thesis, La Sapienza, 2005. http://hdl.handle.net/11573/917424.

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14

Dickman, Rebekah. "Thermodynamic Effects of 5' and 3' Single Strand Dangling Ends on Short Duplex DNA." PDXScholar, 2010. https://pdxscholar.library.pdx.edu/open_access_etds/94.

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Differential scanning calorimetry (DSC) melting analysis was performed on 27 short double stranded DNA duplexes containing 15 to 25 base pairs and short single stranded overhangs from one to 10 bases, on both ends. Molecules have two 5' dangling ends or one 5' and one 3' dangling end. For these molecules the duplex region was incrementally reduced from 25 to 15 base pairs with increased length of the dangling ends from one to 10 bases. A third set of molecules contained 21 base pair duplexes with a four base dangling end on either the 5' or 3' end. Blunt ended duplexes from 15 to 25 base pairs

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15

Pascault, Jean-Roland Eric. "A finite element study of the DNA hybridization kinetics on the surface of microfluidic devices." Link to electronic thesis, 2007. http://www.wpi.edu/Pubs/ETD/Available/etd-043007-170242/.

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16

Tate, Catriona Mary. "Effect of probe-target sequence mismatches on the results of microarray hybridisations : position-dependence, modelling and impact of evolutionary distance." Thesis, University of Manchester, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529202.

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17

Guo, Ruijuan. "Sample comparisons using microarrays: - Application of False Discovery Rate and quadratic logistic regression." Digital WPI, 2008. https://digitalcommons.wpi.edu/etd-theses/28.

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In microarray analysis, people are interested in those features that have different characters in diseased samples compared to normal samples. The usual p-value method of selecting significant genes either gives too many false positives or cannot detect all the significant features. The False Discovery Rate (FDR) method controls false positives and at the same time selects significant features. We introduced Benjamini's method and Storey's method to control FDR, applied the two methods to human Meningioma data. We found that Benjamini's method is more conservative and that, after the number of

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18

Loo, Lit-Hsin Kam Moshe. "Identifying differentially expressed genes in DNA microarray data /." Philadelphia, Pa. : Drexel University, 2004. http://dspace.library.drexel.edu/handle/1860/375.

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19

Tjaden, Brian C. "Computational methods for transcription anlysis using oligonucleotide microarrays /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6907.

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20

Au, Siu Kie. "Gene expression profiling of non-small cell lung cancer using cDNA microarrays /." access full-text access abstract and table of contents, 2009. http://libweb.cityu.edu.hk/cgi-bin/ezdb/thesis.pl?phd-bch-b23749490f.pdf.

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Thesis (Ph.D.)--City University of Hong Kong, 2009.<br>"Submitted to Department of Biology and Chemistry in partial fulfillment of the requirements for the degree of Doctor of Philosophy." Includes bibliographical references (leaves 133-147)

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21

Wang, Tao. "Statistical design and analysis of microarray experiments." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1117201363.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains ix, 146 p.; also includes graphics (some col.) Includes bibliographical references (p. 145-146). Available online via OhioLINK's ETD Center

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22

Engelmann, Julia Cathérine. "DNA microarrays: applications and novel approaches for analysis and interpretation." kostenfrei, 2008. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2008/2974/.

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23

Lemuth, Karin. "Transkriptomanalyse von Escherichia coli unter Kohlenhydrat-Limitierung mittels DNA-Microarrays." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-28479.

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24

Consolandi, C. "Development of DNA microarrays for human single nucleotide polymorphisms detection." Doctoral thesis, Università degli Studi di Milano, 2004. http://hdl.handle.net/2434/62035.

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One major goal of genetic research is to understand the role of genetic variation. By far the most common type of such variation in humans involves single DNA bases, and is termed single nucleotide polymorphism (SNP). In order that DNA chip technology continue to emerge as an alterative to conventional DNA diagnostic methods, questions about the conformation and activity of DNA on surfaces must be addressed. We developed three robust chemical methods for the covalent attachment of amino-modified oligonucleotides on glass surfaces based on polymeric coatings, providing robust platforms to prepa

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25

Fujita, André. "Análise de dados de expressão gênica: normalização de microarrays e modelagem de redes regulatórias." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/95/95131/tde-14092007-173758/.

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A análise da expressão gênica através de dados gerados em experimentos de microarrays de DNA vem possibilitando uma melhor compreensão da dinâmica e dos mecanismos envolvidos nos processos celulares ao nível molecular. O aprimoramento desta análise é crucial para o avanço do conhecimento sobre as bases moleculares das neoplasias e para a identificação de marcadores moleculares para uso em diagnóstico, desenho de novos medicamentos em terapias anti-tumorais. Este trabalho tem como objetivos o desenvolvimento de modelos de análise desses dados, propondo uma nova forma de normalização de dados pr

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26

Li, Shuzhao. "A genomic screen for Zic1 target genes in neural development." Thesis, Montana State University, 2006. http://etd.lib.montana.edu/etd/2006/li/LiS0806.pdf.

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27

Srivastava, Gyan Prakash Xu Dong. "Genome scale meta analysis of microarrays for biological inferences." Diss., Columbia, Mo. : University of Missouri--Columbia, 2009. http://hdl.handle.net/10355/6841.

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Title from PDF of title page (University of Missouri--Columbia, viewed on April 5, 2010). The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Dissertation advisor: Dr. Dong Xu. Vita. Includes bibliographical references.

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28

Szeto, Lap Keung. "Clustering analysis of microarray gene expression data /." access full-text access abstract and table of contents, 2005. http://libweb.cityu.edu.hk/cgi-bin/ezdb/thesis.pl?mphil-it-b19885817a.pdf.

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Thesis (M.Phil.)--City University of Hong Kong, 2005.<br>"Submitted to Department of Computer Engineering and Information Technology in partial fulfillment of the requirements for the degree of Master of Philosophy" Includes bibliographical references (leaves 70-79)

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29

Thompson, Liz. "A label free DNA hybridization sensor." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/26968.

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30

Wong, Tsz-yeung. "Molecular characterization of IBDV-induced apoptosis in vitro using cDNA microarrays." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B36375998.

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31

Alleyne, Renikko. "Tool for the identification of differentially expressed genes using a user-defined threshold /." Link to online version, 2006. https://ritdml.rit.edu/dspace/handle/1850/2363.

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32

Gelmi, Claudio A. "A novel probabilistic framework for microarray data analysis from fundamental probability models to experimental validation /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 177 p, 2007. http://proquest.umi.com/pqdweb?did=1257806411&sid=6&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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33

Leung, Yuk-yee, and 梁玉儀. "An integrated framework for feature selection and classification in microarray data analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43278632.

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34

Pendleton, Carly R. "A simulation-based approach for evaluating gene expression analyses /." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1753.pdf.

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35

Chen, Ilene Y. "Microarray bioinformatics and its applications to clinical research." Phd thesis, Faculty of Engineering and Information Technologies, 2009. http://hdl.handle.net/2123/9327.

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36

Lönnstedt, Ingrid. "Empirical Bayes methods for DNA microarray data /." Uppsala : Matematiska institutionen, Univ. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5865.

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37

Castells, Domingo Xavier. "Towards Objective Human Brain Tumours Classiﬁcation using DNA microarrays." Doctoral thesis, Universitat Autònoma de Barcelona, 2009. http://hdl.handle.net/10803/3624.

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Els tumors de cervell humans (HBTs) són uns dels càncers més agressius i intractables. El sistema actual de diagnosi i prognosi dels HBTs es basa en l'examinació histològica d'un tall de biòpsia, el qual es considera el sistema de referència ("gold¬standard"). A més de ser invasiva, aquesta tècnica no és prou acurada per a diferenciar els graus de malignitat de determinats HBTs i la correlació amb la resposta del pacient a la teràpia sol ser variable. En aquest context, les signatures gèniques obtingudes a partir de microarrays de DNA poden millorar els resultats del "gold-standard". <br/>En a

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38

Kurz, Sebastian Gerhard. "Analyse des Transkriptoms von Neisseria meningitidis Serogruppe B mit DNA-Microarrays." Doctoral thesis, [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=975613944.

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39

Effati, Pedram. "Survey Of Genes Of Escherichia Coli Causing Bovine Mastitis With DNA Microarrays." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-154988.

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Background: Mastitis in dairy cattle is a common ailment worldwide. A cause of mastitis can be bacteria such as Escherichia coli. Mastitis is not a deadly ailment and sometimes the dairy cows show no symptoms but if certain virulence genes are present in the bacteria that cause the mastitis, the bacteria can be transmitted to humans and cause severe diseases. The potential presence of enterohemorrhagic Escherichia coli (EHEC) in particular would be a major concern for human health. Aim: The aim for this study was to analyze the presence of virulence genes known to be present in E.coli strains

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40

Gurrala, Rajesh. "DNA microarrays as a toll in the investigation of animal viral diseases." Thesis, University of Surrey, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549464.

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41

McGinley, Susan. "DNA Chips Boost Dairy Research: Gene Microarrays Target Heat Stress in Cows." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2001. http://hdl.handle.net/10150/622262.

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42

Dawany, Noor Tozeren Aydin. "Large-scale integration of microarray data : investigating the pathologies of cancer and infectious diseases /." Philadelphia, Pa. : Drexel University, 2010. http://hdl.handle.net/1860/3251.

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43

Kirk, Michael School of Biotechnology &amp Biomolecular Science UNSW. "Bioinformatic analyses of microarray experiments on genetic control of gene expression level." Awarded by:University of New South Wales. School of Biotechnology and Biomolecular Science, 2006. http://handle.unsw.edu.au/1959.4/25986.

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The advent of microarray technology, allowing measurement of gene expression levels for thousands of genes in parallel, has made possible experiments designed to investigate the genetic control of variation in gene expression level (described in the literature as ???genetical genomics??? or ???eQTL??? experiments). Published results from these studies, in yeast and in mice, show that genetic variation is an important factor in gene regulation, and furthermore that individual polymorphisms modify the expression level of many genes. The concern of this thesis is the bioinformatic analyses of the

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44

Maughan, Michele Nancy. "Molecular detection and identification of avian influenza viruses by cDNA microarray." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 141 p, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:1440635.

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45

Guo, Ruijuan. "Sample comparisons using microarrays -- application of false discovery rate and quadratic logistic regression." Worcester, Mass. : Worcester Polytechnic Institute, 2007. http://www.wpi.edu/Pubs/ETD/Available/etd-010808-173747/.

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46

Ghanekar, Ruchi. "Cross chip probe matching tool a tool for linking probes from microarrays within and across species /." Birmingham, Ala. : University of Alabama at Birmingham, 2006. https://www.mhsl.uab.edu/dt/2008r/ghanekar.pdf.

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47

Jiang, Ying, and 蔣穎. "Studies of gene regulation using microarray data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B29976388.

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48

Cheung, Kin Lok. "Investigation of (3-mercaptopropyl) trimethoxysilane (MPTS)-modified surface and DNA microarray for genotyping of traditional Chinese medicinal plants /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202003%20CHEUNGK.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 103-111). Also available in electronic version. Access restricted to campus users.

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49

Wong, Tsz-yeung, and 王子揚. "Molecular characterization of IBDV-induced apoptosis in vitro using cDNA microarrays." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B36375998.

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50

Ferguson, Jane A. "Fiber optic chemical sensors : the evolution of high-density fiber-optic DNA microarrays /." Thesis, Connect to Dissertations & Theses @ Tufts University, 2001.

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Thesis (Ph.D.)--Tufts University, 2001.<br>Adviser: David R. Walt. Submitted to the Dept. of Chemistry, Includes bibliographical references (leaves 197-208). Access restricted to members of the Tufts University community. Also available via the World Wide Web;

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