Gotowe bibliografie tematyczne / Drepanoalpha®

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  1. Artykuły w czasopismach

Gotowa bibliografia na temat „Drepanoalpha®”

Autor: Grafiati
Data publikacji: 3 czerwca 2025
Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Drepanoalpha®"

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Benjamin, Z. Gbolo, S. T. Tshibangu Damien, Memvanga Patrick, et al. "Assessment of the Efficacy and Tolerance of Drepanoalpha® in the Management of Sickle Cell Disease in Kinshasa (DR Congo): About Ten Cases." International Journal of Medical and Pharmaceutical Case Reports 9, no. 2 (2017): 1–10. https://doi.org/10.9734/IJMPCR/2017/33658.

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<strong>Aims: </strong>The aim of this study is to assess the efficacy and safety of Drepanoalpha®, a nutraceutical used in the management of sickle cell disease in DR Congo. <strong>Study Design:</strong> Drepanoalpha® to ten sickle patients, evaluation of parameters before and after treatment. <strong>Place and Duration of Study:</strong> Department of Biology, Science faculty, university of Kinshasa, between Sept 2015 and July 2016. <strong>Methodology:</strong> The ten selected cases were submitted to Drepanoalpha® for two months and the following parameters were observed before, during an
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Gbolo, Benjamin, Damien Tshibangu, Lionel Asamboa, et al. "Sickle Cell Anemia Therapeutic Approach Based on Drepanoalpha®: About 34 Cases." Journal of Complementary and Alternative Medical Research 4, no. 2 (2017): 1–8. http://dx.doi.org/10.9734/jocamr/2017/37350.

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Gbolo Zoawe, Benjamin, Amandine Nachtergael, Damien S. T. Tshibangu, et al. "In Vitro Biological Activities of Drepanoalpha® Ethanolic Extract, A Justicia Secunda and Moringa Oleifera-Based Phytomedicine Proposed for The Symptomatic Treatment of Sickle Cell Disease." Journal of Fundamental and Applied Pharmaceutical Science 3, no. 2 (2023): 64–82. http://dx.doi.org/10.18196/jfaps.v3i2.16000.

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Sickle cell disease (SCD) is an autosomal recessive blood disorder characterized by red blood cells that assume an abnormal, rigid sickle shape under low-oxygen conditions. These sickle-shaped erythrocytes tend to lyse, aggregate, and obstruct small blood vessels, leading to major complications. The present study aims to investigate properties that may underlie the activity of Drepanoalphaâ, an antisickling herbal formulation developed in the Democratic Republic of Congo (DRC) for the prevention and symptomatic treatment of sickle cell disease crises. The Drepanoalpha® Ethanolic Extract (DEE)
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Gbolo, Benjamin Zoawe, Bobette Nkongolo Ciala, Jean-Paul Koto-Te-Nyiwa Ngbolua, et al. "Profilage phytochimique par chromatographie sur couche mince haute performance d’extraits de flavonoïdes totaux du Drepanoalpha® et évaluation de leur activité anti-drépanocytaire in vitro." Annales Africaines de Medecine 16, no. 1 (2022): 4882–98. http://dx.doi.org/10.4314/aamed.v16i1.3.

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Contexte et objectif. Le défi le plus important dans la drépanocytose consiste à améliorer l’état de santé des patients dans les pays en développement. L'une des meilleures solutions est donc le développement de la phytomédecine basée sur la connaissance de la pharmacopée traditionnelle. L’objectif de la présente étude était d’évaluer les activités anti-drépanocytaires des flavonoïdes totaux extraits du phytomédicament Drépanoalpha® d’une part et déterminer leur profilage chimique par chromatographie sur couche mince haute performance d’autre part. Méthodes. Les flavonoïdes totaux ont été obte
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Gbolo, Benjamin, Damien Tshibangu, Patrick Memvanga, et al. "Assessment of the Efficacy and Tolerance of Drepanoalpha® in the Management of Sickle Cell Disease in Kinshasa (DR Congo): About Ten Cases." International Journal of Medical and Pharmaceutical Case Reports 9, no. 2 (2017): 1–10. http://dx.doi.org/10.9734/ijmpcr/2017/33658.

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Ngbolua, K., P. Mpiana, D. Tshibangu, et al. "In vitro Antisickling and Radical Scavenging Activities of a Poly-herbal Formula (Drepanoalpha®) in Sickle Cell Erythrocyteand Acute Toxicity Study in Wistar Albino Rats." European Journal of Medicinal Plants 4, no. 10 (2014): 1251–67. http://dx.doi.org/10.9734/ejmp/2014/11861.

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Mpiana, P., F. Kasali, F. Bwirhonde, et al. "Acute and Sub-acute Oral Toxicity Study of Drepanoalpha® (A Poly-Herbal Formula Used in the Management of Sickle Cell Disease) in Guinea-pigs." British Journal of Pharmaceutical Research 10, no. 5 (2016): 1–8. http://dx.doi.org/10.9734/bjpr/2016/24200.

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Koto-te-Nyiwa, Ngbolua. "The Possible Role of a Congolese polyherbal formula (Drepanoalpha) as source of Epigenetic Modulators in Sickle Cell Disease: A Hypothesis." J. of Advancement in Medical and Life Sciences Volume 2, Issue 1 (2014). https://doi.org/10.5281/zenodo.999159.

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The core message of the present paper is to show how we did to transform indigenous data (Traditional Medicine) into knowledge (Science), and then translate knowledge into innovation. The anti-sickle cell anemia activity of Drepanoalpha® could be due to its epigenetic modulator effect as revealed by the testimony’s of all patients received the product. Drepanoalpha® reduces the frequency of their crises and improves their general state and their hemoglobin level. All the treated patients have normal phenotype if compared them to normal individuals and have not made any more crises for more tha
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Koto-te-Nyiwa, Ngbolua. "Drepanoalpha: An Overview on the Quality Control Process and Standardization Feature of an Antisickling Herbal Drug from Democratic Republic of the Congo." J. of Modern Drug Discovery And Drug Delivery Research Volume 4, Issue 1 (2016). https://doi.org/10.5281/zenodo.891500.

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Sickle cell disease (SCD) is an autosomal recessive type of hemoglobin disorder. Nowadays, the main challenge is how to improve the clinical aspects of life quality of the patients with low toxicity and safer therapy from indigenous knowledge. Democratic Republic of the Congo is one of the biodiversity rich countries in the world and can play the lead role in production and commercialization of standardized antisickling formulations like Drepanoalpha® worldwide. In this research paper, various methods of phytochemical standardization, such as TLC, HPTLC, HPLC, UV-Vis, IR, MS and their hyphenat
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