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Rozprawy doktorskie na temat „Dynamic full field optical coherence tomography”

Autor: Grafiati

Data publikacji: 23 listopada 2024

Data aktualizacji: 31 lipca 2025

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1

Fergusson, James. "Full field swept source optical coherence tomography." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/49959/.

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Optical Coherence Tomography (OCT) is a non-invasive volumetric imaging technique that offers micron scale resolution over several millimetres of depth penetration in tissue. The aim of the project was to develop Full Field Swept Source OCT (FFSSOCT), charting the specifications of the system throughout and drawing comparisons with available Fourier domain OCT (FDOCT) systems. A super luminescent diode (SLD) light source was tuned to different optical frequencies using an acousto-optical tunable filter. The successive optical frequencies were distributed across the sample in parallel and the s

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Thouvenin, Olivier. "Optical 3D imaging of subcellular dynamics in biological cultures and tissues : applications to ophthalmology and neuroscience." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCC169/document.

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Cette thèse a pour objectif l’étude d’un lien effectif potentiel entre la motilité cellulaire, la mécanique cellulaire, et l’activité biochimique de ces mêmes cellules. Ce couplage a été étudié dans divers systèmes biologiques, et aussi bien dans des cultures de cellules qu’à l’intérieur de tissus plus complexes. Notamment, nous avons particulièrement cherché à détecter un couplage électromécanique dans des neurones qui pourrait être impliqué dans la propagation du message nerveux.Pour ce faire, nous avons dû développer deux microscopes optiques à la sensibilité extrême. Ces microscopes se com

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Apelian, Clément. "Imagerie Optique Multimodale des tissus par Tomographie Optique Cohérente Plein Champ." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLET009/document.

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La tomographie de cohérence optique plein champ est une technique de microscopie permettant d’imager un plan d’intérêt en profondeur dans un milieu diffusant. Cette technique a été utilisée pour l’examen de pièces opératoires dans un but de diagnostic en cancérologie. L’utilisation de cette technique permettrait en effet de fournir un outil de diagnostic peropératoire rapide et fiable, évitant ainsi de nombreuses procédures de réopération. Ces réopérations peuvent survenir lorsque – lors du diagnostic final par analyse de coupes histologiques – le pathologiste décèle la présence de tissus canc

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Azzollini, Salvatore. "Developing live microscopy for retinal disease modeling." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS239.pdf.

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Mon projet de doctorat a été consacré à la conception et à l'application de techniques de microscopie optique non invasives, tridimensionnelles, sans marquage et en direct pour la modélisation des maladies rétiniennes à haute résolution. Aux frontières de la physique, de l'ingénierie et de la biologie, la principale question qui a motivé mon travail était de caractériser la santé de cellules dans des tissus complexes, avec une perturbation externe minimale. En particulier, j'ai contribué au développement d'une nouvelle modalité d'imagerie appelée tomographie par cohérence optique plein champ d

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Mandache, Diana. "Cancer Detection in Full Field Optical Coherence Tomography Images." Electronic Thesis or Diss., Sorbonne université, 2022. http://www.theses.fr/2022SORUS370.

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Le cancer est une des principales cause de décès dans le monde et donc un problème majeur de santé publique. Plusieurs techniques d'imagerie biomédicale servent à la recherche et aux efforts cliniques pour améliorer le pronostic du patient. Nous étudions l'utilisation d'une nouvelle famille de techniques d'imagerie, la tomographie par cohérence optique plein champ statique et dynamique, qui permet une analyse du tissu plus rapide que la technique de référence en histopathologie. Afin de faciliter l'interprétation de cette nouvelle imagerie, nous développons plusieurs méthodes exploratoires bas

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Li, Chen. "Development of a simple full field optical coherence tomography system and its applications." Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2044939/.

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Optical coherence tomography (OCT) is a versatile and powerful imaging technique widely used in biomedical applications. It employs non-destructive radiation and performs non-contact micrometre-scale cross-sectional imaging of the sample structure. However, classic OCT systems generally apply a single-point detection scheme, which creates inefficiencies in terms of the experimental alignment of system, the point-by-point signal acquisition process and the measurement speed. One of its variants, full-field optical coherence tomography (FF-OCT) employs parallel illumination and directly acquires

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Zhang, Jinke. "Development of time-domain full-field optical coherence tomography as a non-destructive testing method." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3015759/.

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Optical coherence tomography (OCT) serves as a non-destructive and non-invasive technique that is capable of imaging the inner structure of optical scattering samples with a high spatial resolution and deep penetration depth. Full-field time-domain OCT (FF-TD-OCT) is an extension of time-domain OCT (TD-OCT) which uses a two-dimensional (2D) detector to capture a series of en-face images to reconstruct the inner structure of samples in three-dimension (3D). In pharmaceutical industry, the pellet or tablet coating performs an important role in the release of active pharmaceutical ingredients (AP

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Cai, Yao. "Design and implementation of Adaptive Optics Full-Field Optical Coherence Tomography for in-vivo retinal imaging." Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS685.

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La rétine, en tant que fenêtre sur le cerveau, est directement connectée au système nerveux central. L'imagerie rétinienne in vivo est prometteuse pour fournir des signes de maladies neurodégénératives à un stade précoce avec une imagerie cellulaire de haute résolution. Cependant, la présence de mouvements oculaires en 3D et d'aberrations oculaires dégrade le rapport signal/bruit et la résolution de l'image. La technique de tomographie par cohérence optique plein champ dans le domaine temporel (TDFFOCT) a démontré une résolution 3D élevée et une faible complexité du système pour l'imagerie rét

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Perrin, Stephane. "Development and characterization of an optical coherence tomography micro-system : Application to dermatology." Thesis, Besançon, 2016. http://www.theses.fr/2016BESA2002/document.

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Ce manuscrit de thèse de doctorat présente la conception et la réalisation d’un système d’imageriepour le diagnostic précoce des pathologies de la peau. Un diagnostic précoce permet de réduire lesactes chirurgicaux inutiles. Il est important de mettre en avant que seulement 20% des pathologiesfaisant office d’une opération chirurgicale, sont malignes. De plus, les pronostics de l’année 2015avançaient trois millions de nouveaux cas de cancer de la peau diagnostiqués aux ´ Etats-Unis. Basésur la tomographie par cohérence optique à balayage en longueur d’onde et une configuration pleinchamp et mu

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Lullin, Justine. "Design, simulation and fabrication of a vertical microscanner for phase modulation interferometry - Application to optical coherence tomography system for skin imaging." Thesis, Besançon, 2015. http://www.theses.fr/2015BESA2010/document.

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Cette thèse décrit le design, la simulation et la fabrication d’une matrice 4x4 de micro-miroirs actionnée verticalement et munie d’un capteur de position. Le micro-scanneur vertical a pour vocation à être intégré au sein d’un micro-interféromètre de Mirau de type matriciel, réalisé àbase de composants micro-optiques fabriqués grâce à des méthodes collectives. Le mouvement du micro-scanneur, développé dans cette thèse, génère un signal de référence utilisé pour l’implémentation de l’interférométrie à modulation de phase dans un système de tomographie par cohérence optique (OCT). Dans un premie

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Molnar, Anna. "Structure and Function of the Retina in Children Born Extremely Preterm and in Children Born At Term." Doctoral thesis, Uppsala universitet, Oftalmiatrik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-317550.

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Background: Optical coherence tomography (OCT), multifocal electroretinography (mfERG) and full-field electroretinography (ffERG) give important information about retinal structure and function. Purpose: To collect normative data of macular Cirrus Spectral domain (SD)-OCT assessments and of mfERG measurements of healthy children (papers I and II). To assess the macular thickness with Cirrus SD-OCT and the retinal function with ffERG in 6.5-year-old children born extremely preterm and in children born at term (papers III and IV). Methods: Study participants aged 5-15 years and living in Uppsala

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Nahas, Amir. "Imagerie multimodale optique, élastique et photo-thermique des tissus biologiques par OCT plein champ." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066680/document.

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L’OCT plein champ est une technique d’imagerie permettant de faire de la microscopie des milieux diffusants à une profondeur donné à l’aide d’un système interférométrique. L’un des principaux objectifs qui ont motivé le développement de l’OCT plein champ ces dernières années a été de pouvoir fournir au chirurgien, durant les opérations des images similaires aux coupes histologiques mais en temps réel. Actuellement, les diagnostiques effectué à partir des images d’OCT plein champs donne de bon résultats, notamment dans le cas de certaine pathologie mammaire. Cependant, la différence majeure ent

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Xiao, Peng. "Optique adaptative et interférométrie spatialement incohérente plein champ pour l’imagerie de la rétine." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLET015/document.

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Cette thèse traite de l’étude et du développement d’un système d’optique adaptative pour la tomographie par cohérence optique plein champ (AO-FFOCT en anglais) appliquée à l’imagerie haute résolution de la rétine. L’analyse de l’effet des aberrations géométriques sur les performances en FFOCT a montré que pour une illumination spatialement incohérente, la résolution transverse est insensible aux aberrations et ne fait que diminuer le niveau du signal. Comme ce sont des aberrations de bas ordres comme la myopie et l’astigmatisme qui prédominent pour l’œil humain, une méthode d’optique adaptativ

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Leong-Hoï, Audrey. "Etude des techniques de super-résolution latérale en nanoscopie et développement d'un système interférométrique nano-3D." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAD048/document.

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Ce manuscrit de thèse présente l’étude des techniques de super-résolution latérale en nanoscopie optique, qui est une des nouvelles techniques d'imagerie haute résolution, aujourd'hui largement utilisée en biophysique et en imagerie médicale, pour imager et caractériser des nanostructures, tout en conservant les avantages de l'imagerie optique en champ lointain comme un vaste champ, la visualisation et l’analyse en temps réel…Un des défis futurs de la microscopie 3D super-résolue est d’éviter l’utilisation des marqueurs fluorescents. La microscopie interférométrique fait partie des techniques

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Lin, Yen-Hung, and 林彥宏. "Skin Measurements and Analysis on Dynamic Properties Using Mirau-based Full-field Optical Coherence Tomography." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/92152339515271626594.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>104<br>In this thesis, Mirau-based full-field optical coherence tomography system using homemade Ti:sapphire crystal fiber amplified spontaneous emission (ASE) as light source was demonstrated. The lateral and axial resolution of the system are 1.25 μm and 1.3 μm in tissue, respectively. High-resolution in-vivo human skin images acquired from various locations such as dorsal forearm, palm, finger and wrist were demonstrated. Besides the morphology, dermal-epidermal junction, sweat gland, pore and vessel could be found out. The stratum corneum thickness was compared

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Lin, Yao-Sheng, and 林耀聖. "Study of full-field optical coherence tomography." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/63214147970510298732.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>102<br>Optical coherence tomography (OCT) has become one of the most important techniques in biomedical imaging realm. Its axial resolution is determined by central wavelength and bandwidth of the light source. Due to this reason, we made the Ce3+:YAG single-cladding crystal fiber, which generate amplified spontaneous emission centered at 560 nm with bandwidth of 95 nm. And we use it as the light source to demonstrate a full-field OCT with axial resolution of 1.468 μm and lateral resolution of 1.28 μm. In this thesis, we discuss about axial-first and lateral-first i

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Chen, Yu-Tung, and 陳昱彤. "Animal Eye Models Using Full-field Optical Coherence Tomography." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/fnak48.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>106<br>Accurate diagnosis of corneal pathology and morphological identification of different corneal layers require clear delineation of corneal three-dimensional structures and en face or cross-sectional imaging of palisade of Vogt (POV), neovascularization or corneal nerves. Here we report a prototype of full-field optical coherent tomography (FF-OCT) system with isotropic sub-micron spatial resolution in the en face and cross-sectional views. It can also provide three-dimensional reconstructed images and a large field of view by stitching tomograms side by side.

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Wang, Chien-yell, and 王健燁. "Full-Field Optical Coherence Tomography by Using QHQ Phase Shifter." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/36555197648411509161.

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碩士<br>逢甲大學<br>光電研究所<br>98<br>This study provides a full-field optical coherence tomography (OCT) by using a QHQ phase shifter. The image quality of the proposed OCT is less affected by the phase shift error. The OCT system is composed of a superluminescent diode, polarization Linnik interferometer, QHQ phase shifter, and CCD. Four interferometric images corresponding to phase shifts of 0°, 90°, 180° and 270° are recorded. The phase shift is introduced between the measurement and reference beams by rotating the half-wave plate in the OHQ phase shifter. A two-dimensional cross-sectional image of

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Wang, Yu-Yen, and 王友延. "Full-field optical coherence tomography for three-dimensional dermal tissue imaging." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/g952pb.

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碩士<br>元智大學<br>光電工程學系<br>104<br>Conventional handheld skin cameras are suitable for two-dimensional (2D) inspection of shallow skin. With noninvasiveness and high resolution, optical coherence tomography (OCT) has become a popular medical imaging technology. Among OCT schemes, full-field optical coherence tomography (FF-OCT) is suitable for rapid three-dimensional (3D) imaging, as it uses a 2D imaging device for pixel processing of a sample plane. Conventionally, the use of low-coherent infrared light sources in OCT resulted in monochromatic images. As light emitting diode (LED) has advantages

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Hsieh, Cho-Yen, and 謝卓諺. "Planar Liquid Crystal Phase Shifter for Full-Field Optical Coherence Tomography." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/95545748958992414540.

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碩士<br>逢甲大學<br>光電研究所<br>99<br>This research presents a planar liquid-crystal (PLC) phase shifter for full-field optical coherence tomography (FF-OCT). The proposed device consists of three PLC half-wave plates sandwiched between two quarter-wave plates. Compared with traditional achromatic phase shifters with a rotating wave plate or polarizer, the PLC device can quickly generate phase shifts without mechanical vibrations. Three different drive methods are applied to the PLC cells, and three different phase shifts, -120°, 0°, and 120°, are introduced between the measurement and reference beams

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Chang, Chia-Kai, and 張家凱. "Quantitative analyses of human skin using full-field optical coherence tomography." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/2fg97j.

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博士<br>國立臺灣大學<br>光電工程學研究所<br>106<br>In the past, the quantitative analysis of biological cell is to establish information via two-dimensional (2D) images. Now, raw volumetric images were acquired through a full-field optical coherence tomography (FF-OCT) system with submicron resolution—i.e. 0.8 µm in lateral and 0.9 µm in axial direction. With the tomographic volumetric image data, more comprehensive information could be acquired. A random rayburst sampling (RRBS) framework was developed to detect the nucleus and cell membrane boundaries in three-dimensional (3D) space for determining the volu

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Shih, Cheng-Hung, and 施承宏. "Analysis of Corneal Nerve Image by Using Full-field Optical Coherence Tomography." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/n77wem.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>107<br>Construct clear delineation of corneal three-dimensional, en-face and cross sectional imaging provide more complete information to accurate diagnosis of corneal pathology and morphological identification of different corneal layers. Changes in corneal neuromorphic parameters are associated with ocular diseases. Thus, more precise technologies for analyzing innervation architecture of the cornea will be required. Here we develop Ce3+:YAG and Ti:sapphire light source full-field optical coherence tomography (FF-OCT) systems with isotropic micron spatial reso

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Chiu, Yu-Kuang, and 邱宇光. "Study of Full-field Optical Coherence Tomography for In-vivo Rat Eye Characterization." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/774v9j.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>105<br>Early stage diagnosis has been shown to be an efficient way to prevent the deterioration of eye diseases. In recent years, optical coherence tomography (OCT), as an important clinical imaging modality, has been widely used in clinical diagnosis in ophthalmology, helping follow the diseases progression and monitor response to therapy. Full-field optical coherence tomography (FF-OCT), a branch of OCT, has a simple setup, and its scanning speed is comparable to other fast-scanning OCT configuration, like sweep source OCT. In this work, two FF-OCT systems which b

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Lai, Yen-Lian, and 賴彥良. "The improvement of Mirau interferometer for the Mirau0based full-field optical coherence tomography." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/bks97q.

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碩士<br>國立臺灣科技大學<br>電子工程系<br>106<br>In this thesis, Cr:forsterite crystal fiber amplified spontaneous emission(ASE) light source was used to build a Mirau-based full-field optical coherence tomography system using two 520-nm laser diode to pump the different axis Cr:forsterite crystal fiber. The C-axis fiber can generate 3-mW ASE light centered at 900 nm with a bandwidth of 250 nm was generated. The B-axis fiber generated ASE light centered at 900nm with a bandwidth of 200um. The mirau-based full-firld OCT has an axial resolution of 1.2um and a lateral resolution of 0.98um. Skin biopsy is the go

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Wu, Jheng-Yu, and 吳政育. "Full-field Optical Coherence Tomography Combined with Raman Spectroscopy for Biological Sample Characterization." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/u7fjwr.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>106<br>Complete characterization of biological tissue requires probing the morphological and biochemical information. Optical coherence tomography (OCT) excels at presenting three-dimensional (3-D) images of tissue microstructure but lacks biomolecular information, while Raman spectroscopy is capable of providing tissue biochemical composition with superb specificity, but cannot gather 3-D microstructure. In order to obtain the complete biological sample information, in this work, we develop an integrated full-field OCT (FF-OCT) and Raman spectroscopy system capable

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Wu, Dong-Yi, and 吳東憶. "In-Vivo Skin Measurement Using High Definition Mirau-based Full Field Optical Coherence Tomography." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/23357323912978273342.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>103<br>Skin biopsy is the gold standard for doctors to diagnosis skin cancers. There are several ways to do a skin biopsy such as punch biopsy, shave biopsy, incisional biopsy. These methods are all invasive that make the patient bleed and leave scar. Optical coherence tomography (OCT) is one of the most important techniques in biomedical imaging realm. It is a noninvasive, label-free, and 3D imaging method. In this thesis, a homemade Ti:sapphire crystal fiber amplified spontaneous emission (ASE) light source was used to build a Mirau-based full-field optical coher

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Chang, Ting-Wei, and 張庭瑋. "Performance of white light LED as a light source in Full Field Optical Coherence Tomography." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/42537440483747844502.

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碩士<br>國立陽明大學<br>生醫光電研究所<br>103<br>Optical coherence tomography (OCT) is an imaging technique that permits non-invasive and non-contact cross-sectional imaging of an object. Full-field (FF) OCT differs from time-domain and frequency-domain OCT by producing tomographic images in the en-face orientation without scanning a light beam. The entire field of the image is illuminated with a low coherence source, such as a tungsten-halogen lamp or super luminescent diode (SLD). An image sensor, such as a charge-coupled device (CCD) camera, is used for parallel acquiring of the interferometric signals. M

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Chiang, Shu-Chi, and 姜舒綺. "Study of Corneal Regeneration on Acellular Porcine Cornea Matrix by Full-field Optical Coherence Tomography." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/d44ee6.

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碩士<br>國立臺灣大學<br>醫學工程學研究所<br>106<br>The cornea is a transparent film in the front of the eye. Diseases of the cornea may lead to corneal opacification, visual impairment and even blindness. Corneal transplant surgery is a common corneal surgery, but also the high rate of success in all organ transplantations. However, there is a severe shortage of suitable cornea donors in many countries with an increased use of the old-aged population and corrective laser surgery. Therefore, the aim of this study was to construct a corneal replacement using acellular porcine corneal matrix (APCM) as a scaffold

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Lin, Jheng-Ting, and 林政廷. "In Vivo Skin and Cornea Using High-speed Mirau-based Full-field Optical Coherence Tomography." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/67qvpb.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>107<br>For precise diagnosis skin and cornea pathology, en face and cross-section images are required to determine the exact pathological position, structure and cell morphology at the same time. Full-field optical coherence tomography (FF-OCT) is a kind of time-domain OCT, that scans different depth of tissues by moving PZT linear stage and collects 2-D images by camera to construct 3-D tomogram in real time. The scanning speed is depended on the frame rate of camera. Nowadays, the scanning speed of most FF-OCT are too slow, so scanning tissue will spend too much t

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Chou, Ting-Ching, and 周庭慶. "Utilizing Mirau-Based Full-Field Optical Coherence Tomography Combined with Fluorescence Microscope on Skin Melanoma Diagnosis." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/00088905431872439536.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>104<br>Mirau-based full-field optical coherent tomography (Mirau FF-OCT) is a three-dimensional (3D) optical imaging system that has characteristics of non-invasive, no specific demand in preparing the sample and high spatial resolution. It has been tried to be used in clinically dermatology research lately, but part of cases are hard to distinguish lesion correctly. Fluorescence microscopy (FM) uses fluorescence dye to label biological molecule of interest, so it can only present image of specific target. We use immunofluorescence techniques to aid OCT in melanoma

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Fan, Jiun-Yu, and 范君宇. "Assessment of Full-Field Optical Coherence Tomography for Imaging the Moving Scatter in Onion Epidermal Cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/32267145135731981279.

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碩士<br>國立陽明大學<br>生醫光電研究所<br>102<br>Full-field optical coherence tomography (FFOCT) is based on low coherence interferometry to extract the three-dimension backscattering images of the sample. OCT with single-point scanning required many B-scan images from scanning to reconstruct an en-face image. Thus, in order to save the time for obtaining en-face images, we used FFOCT setup in this study. In this research, a novel application is proposed that is FFOCT combines the angiographic algorithm to assess the moving backscatter in cells. In the experiment, we used the onion cells as a test sampl

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Anna, Tulsi. "Full-field frequency domain optical coherence microscopy for simultaneous topography and tomography of engineering ann biological materials." Thesis, 2012. http://localhost:8080/xmlui/handle/12345678/4560.

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Cheng, Chia-Yi, and 鄭家宜. "The feasibility of dynamic imaging using high resolution full-field optical coherence microscopy(FF-OCM)." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/4m93dk.

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Chen, Chih-Ying, and 陳致穎. "New light source for Mirau-based full-field optical coherence tomography by using Cr:forsterite crystal fiber light source." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/09014433743107212863.

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碩士<br>國立臺灣科技大學<br>光電工程研究所<br>104<br>skin biopsy is the gold standard for doctor to diagnosis skin cancers. There are several ways to do the skin biopsy such as punch biopsy, shave biopsy, incisional biopsy, incisional biopsy. These methods are all invasive that make the patient bleed and leave scar. Optical coherence tomography is one of the techniques in the biomedical imaging system. It is a noninvasive, label-free and 3D imaging method. In this thesis, Cr:forsterite crystal fiber amplified spontaneous emission(ASE) light source was used to build a Miura-based full-field Optical coherence t

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You, Cian, and 游鈐. "Analysis of Image and Spectrum Properties on Skin Cells by Mirau-based Full-field Optical Coherence Tomography Combined with Near-infrared Raman Spectroscopy." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/wpqjq6.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>107<br>Mirau-based full-field optical coherence tomography (FF-OCT) has many advantages such as high resolution, low vibration noise, and good dispersion compensation. Thus it can observe the morphology and intensity distribution of the sample but not its chemical component. Near-infrared (NIR) Raman spectroscopy can recognize the chemical institution of the sample with the advantages of low fluorescent effect and deep penetration, but not its microstructure. Therefore, measuring the five skin in vitro cell lines, including Keratinocyte cell lines, Basal cell carcin

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