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Rozprawy doktorskie na temat „Dynamic membranes”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 25 lipca 2025

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1

Magi, Ross. "Dynamic behavior of biological membranes." Thesis, The University of Utah, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3680576.

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<p> Biological membranes are important structural units in the cell. Composed of a lipid bilayer with embedded proteins, most exploration of membranes has focused on the proteins. While proteins play a vital role in membrane function, the lipids themselves can behave in dynamic ways which affect membrane structure and function. Furthermore, the dynamic behavior of the lipids can affect and be affected by membrane geometry. A novel fluid membrane model is developed in which two different types of lipids flow in a deforming membrane, modelled as a two-dimensional Riemannian manifold that resists
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2

Waheed, Qaiser. "Molecular Dynamic Simulations of Biological Membranes." Doctoral thesis, KTH, Teoretisk biologisk fysik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-102268.

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Biological membranes mainly constituent lipid molecules along with some proteins and steroles. The properties of the pure lipid bilayers as well as in the presence of other constituents (in case of two or three component systems) are very important to be studied carefully to model these systems and compare them with the realistic systems. Molecular dynamic simulations provide a good opportunity to model such systems and to study them at microscopic level where experiments fail to do. In this thesis we study the structural and dynamic properties of the pure phospholipid bilayers and the phase b
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Ip, Anita Wai Ching Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Dynamic membranes: formation and characterisation studies." Awarded by:University of New South Wales, 2005. http://handle.unsw.edu.au/1959.4/37836.

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Dynamic membranes are considered to be an attractive anti-fouling remedy for membrane filtration, because once fouled, they can be removed and reformed in-situ, thereby prolonging the support membrane???s lifetime. However, large-scale application of dynamic membranes has been limited due to the numerous formation parameters that influence their properties. This thesis provides better understanding of the mechanisms of the dynamic membrane formation process through fundamental formation and characterisation studies of dynamically formed titanium dioxide membranes in laboratory scale dead-end
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Turkson, Abraham K. "Electro-ultrafiltration with rotating dynamic membranes." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72036.

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In axial electrofiltration, a DC electric field is imposed between a rotating inner cylinder and a stationary outer cylinder giving rise to four mechanisms which act to minimize solute accumulation at the filter surface: turbulence, centrifugal force, electrophoresis and shear stress which removes solute aggregates.<br>Four dynamic membranes, Zr(IV) oxide, calcium oleate, poly-2-vinylpyridine and cadmium sulfide, were used to filter bovine serum albumin (BSA) in a disodium phosphate solution at pH = 8 and Prussian blue in distilled water. Prussian blue is a particle of 0.01(mu)m diameter with
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5

SOARES, RENATA MACHADO. "DYNAMIC ANALYSIS OF HYPERLASTIC CIRCULAR MEMBRANES." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2009. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=13790@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>FUNDAÇÃO DE APOIO À PESQUISA DO ESTADO DO RIO DE JANEIRO<br>Nesta tese são estudadas as vibrações não-lineares de membranas circulares inicialmente tracionadas sujeitas a deformações finitas. O material da membrana é modelado como um material hiperelástico neo-Hookeano, isotrópico e incompressível. Baseada na teoria de deformações finitas para membranas hiperelásticas, uma formulação variacional é desenvolvida. Pr
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6

McCarthy, Nicola L. C. "Imaging dynamic patterning in lipid membranes." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/44075.

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Lateral inhomogeneity in biological membranes has been linked with many cellular functionalities including protein sorting and signal transduction. Fluid phase coexistence has been extensively studied by modelling membranes as bulk mesophases and as giant unilamellar vesicles (GUVs). However, the basis for microdomain formation in cells remains uncertain, and this is thought to be due to the small domain size and the highly dynamic nature of the cell membrane. The application of high pressure technology offers an ideal biophysical tool for the study of phase behaviour in model membranes both i
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Saleem, Mubbshir. "Application of dynamic membranes in wastewater treatment." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3422308.

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The research highlighted the performance of dynamic membrane (DM) in most challenging conditions where advanced technologies like MBR etc. have been successfully applied. In this regard, treatment of old landfill leachate, production of bio hydrogen and enrichment of Anammox bacteria was mostly focused. The research also presented the strategies to expedite the formation of DM under both aerobic and anaerobic conditions. Pneumatic In situ cleaning mechanism was also proposed and proved to be effective in speedy and effective permeability recovery of excessively fouled DM under anaerobic condit
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8

Nandurkar, Kuldeep Pandurang. "Static and Dynamic Behavior of Stress Coated Membranes." Thesis, Montana State University, 2006. http://etd.lib.montana.edu/etd/2006/nandurkar/NandurkarK0806.pdf.

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Large space mirrors need to be made of ultra-lightweight materials (membranes) that have very low densities and high flexibility (compliance) for packaging. A coating application necessary for optical reflectivity may also impart to these ultra-lightweight materials a desired shape and to help maintain that shape in the harsh environment of space. When a coating is applied on the membrane substrate, stresses develop in the coating due to atomistic processes. These stresses are fundamental to the final shape of the substrate. Coatings applied to the substrate in order to maintain a particular s
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9

Al-Malack, Muhammad Hassan. "Applications of dynamic membranes to crossflow microfiltration of secondary effluent." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335944.

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10

Thurmond, Robin Leroy. "Average and dynamic properties of membrane lipids studied by deuterium NMR spectroscopy." Diss., The University of Arizona, 1992. http://hdl.handle.net/10150/185835.

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If the function of membrane lipids were only to provide a permeability barrier for cells, than a single lipid species such as phosphatidylcholine would suffice since it would maintain the bilayer structure necessary for a membrane. Cells, however, go out of their way to regulate the components of their membranes and therefore there must be some reason for the vast diversity of lipids found even in a single membrane. Modulation of the phospholipid composition could affect both the average and dynamical properties of the entire system. Average properties such as the hydrocarbon thickness, the ar
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11

Winkler, Pamina M. "Novel planar photonic antennas to address the dynamic nanoarchitecture of biological membranes." Doctoral thesis, Universitat Politècnica de Catalunya, 2020. http://hdl.handle.net/10803/670293.

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The cell membrane is the encompassing protective shield of every cell and it is composed of a multitude of proteins, lipids and other molecules. The organization of the cell membrane is inextricably intertwined with its function, and sensitive to perturbations from the underlying actin cytoskeleton and the extracellular environment at the nano- and the mesoscale. Elucidating the dynamic interplay between lipids and proteins diffusing on the cell membrane, forming transient domains and (re)organizing them according to signals from the juxtaposed inner and outer meshwork, is of paramount interes
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12

Saggiomo, Vittorio [Verfasser]. "Ion transport across membranes mediated by a dynamic combinatorial library / Vittorio Saggiomo." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019984619/34.

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13

Fox, Jason William. "Electromechanical Characterization of the Static and Dynamic Response of Dielectric Elastomer Membranes." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/34909.

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Dielectric elastomers (DEs) are a relatively new electroactive polymer (EAP) transducer technology. They are capable of over 100% strain when actuated, and can be used as sensors to measure large strains. In actuation mode, the DE is subject to an electric field; in sensing mode, the capacitance of the dielectric elastomer is measured. In this work, a dielectric elastomer configured as a circular membrane clamped around its outer edge over a sealed chamber and inflated by a bias pressure is studied in order to characterize its static and dynamic electromechanical behavior. In both cases, t
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14

Roso, Martina. "Multistructured membranes based on electro-dynamic technologies: process optimization and catalytic performances." Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426399.

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Electodynamic technologies represent a challenging task in the nanotechnology field for producing multistructured and multifunctional membranes, based on nanofibers and nanoparticles that have been shown to be a good candidate as photocatalytic membrane on VOCs degradation. Before going toward fabrication of multistructured membranes, it is necessary to optimize the process of fiber formation. At this regard Response Surface Methodology (RSM) represents a versatile tool for exploring the space of the process or independent variables, empirical statistical modeling to develop an appropriate app
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15

Mahon, Eugene. "Dynamic Constitutional Protein-Carbohydrate and Polyoxometalate Systems toward biomimetic sensors and membranes." Montpellier 2, 2009. http://www.theses.fr/2009MON20057.

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Le but de ce travail était d'explorer l'interaction entre les ensembles supramoléculaires constitutionnels et chimie dynamiques biomimétique et les motifs biologiques simples. La recherche a été effectuée dans les domaines d'intérêt suivants : l'interaction protéine-saccharides, les vésicules, les bicouches phospholipidiques, les canaux ioniques et le transport à travers une membrane et ont constituer trois axes de projet. Des nanoparticules ont été employée pour l'amplification de signal de fréquence d'une microbalance à cristal de quartz pour la recherche sur l'interaction de lectin-sacchari
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16

Dietrich, Undine. "Structural and dynamic studies of MARCKS interaction with PIP(2) containing lipid membranes." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-77727.

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MARCKS-Protein ist in den Signalübertragungsweg der Zelle involviert. Durch einen Adsorptions-/Desorptionszyklus mit der Zellmembran reguliert es die Konzentration bestimmter Botenmoleküle. Im Rahmen dieser Arbeit wurde untersucht, inwieweit strukturelle Änderungen der Membran, verursacht durch die Membran-Protein-Wechselwirkung, mit einem Reaktions-Diffusions-System korrelieren. Die elektrostatische Wechselwirkung von MARCKS-Protein mit negativ geladenen Membranlipiden geschieht an der inneren Seite der Zellmembran. Als Modellsystem lässt sich dies mit einer monomolekularen Lipidschicht an de
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17

Kapoor, Hitesh. "Nonlinear Dynamic Response of Flexible Membrane Structures to Blast Loads." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/41238.

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The present work describes the finite element (FE) modeling and dynamic response of lightweight, deployable shelters (tent) to large external blast loads. Flexible shelters have been used as temporary storage places for housing equipments, vehicles etc. TEMPER Tents, Small Shelter System have been widely used by Air Force and Army, for various field applications. These shelters have pressurized Collective Protection System (CPS), liner, fitted to the frame structure, which can provide protection against explosives and other harmful agents. Presently, these shelter systems are being tested for
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18

Longun, Jimmy. "Processing and Evaluation of Multifunctional Polyimide Composite Coatings and Membranes." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1367938249.

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19

Comer, Anthony C. "DYNAMIC RELAXATION PROPERTIES OF AROMATIC POLYIMIDES AND POLYMER NANOCOMPOSITES." UKnowledge, 2011. http://uknowledge.uky.edu/cme_etds/1.

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The dynamic relaxation characteristics of Matrimid® (BTDA-DAPI) polyimide and several functionalized aromatic polyimides have been investigated using dynamic mechanical and dielectric methods. The functionalized polyimides were thermally rearranged to generate polybenzoxazole membranes with controlled free volume characteristics. All polyimides have application in membrane separations and exhibit three motional processes with increasing temperature: two sub-glass relaxations (ƴ and β transitions), and the glass-rubber (α) transition. For Matrimid, the low-temperature ƴ transition is purely non
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20

Zarragoitia, Gonzalez Alain. "Développement de modèles dynamiques pour la simulation et l'optimisation de bioréacteurs à membranes immergées pour le traitement d'eaux usées." Thesis, Toulouse, INPT, 2009. http://www.theses.fr/2009INPT016G/document.

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Le traitement des effluents et eaux usées par bioréacteurs à membranes immergées (BAMI) permet d'obtenir une haute qualité de perméat par une dégradation biologique et une séparation physique. Néanmoins, le procédé de filtration est limité par l'influence de facteurs très complexes, en particulier le colmatage de la membrane. Le but du travail est de développer des modèles dynamiques et de simuler le procédé de filtration dans les BAMI. Le développement et la simulation des modèles ont été ciblés sur la description des rapports existants entre les variables les plus importantes du système, com
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21

Corre, Thomas. "Rupture dynamique de membranes élastomères : étude expérimentale par mesure de champs." Thesis, Ecole centrale de Nantes, 2018. http://www.theses.fr/2018ECDN0043/document.

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Cette thèse s’intéresse à la propagation dynamique de fissure dans les membranes élastomères du point de vue expérimental. Elle a pour but d’identifier les paramètres qui gouvernent la cinématique de ces fissures se propageant à grande vitesse, afin d’en prédire la trajectoire. Fondé sur l’utilisation conjointe d’une caméra à haute résolution et d’une caméra rapide, le dispositif expérimental permet de mesurer des champs à partir de la corrélation d’images au cours de la propagation de la fissure. Mis en pratique sur un polyuréthane, ce dispositif permet de retrouver la configuration de référe
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22

Günther, Jan. "Caractérisation et optimisation des phénomènes de transfert dans un double bioréacteur à membranes." Thesis, Toulouse, INPT, 2009. http://www.theses.fr/2009INPT047G/document.

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L'idée de base est de permettre à deux microorganismes de partager le même environnement tout en les maintenant séparées à l'aide d'une membrane perméable les retenant sélectivement. La principale contrainte résulte du transfert des composées d'intérêts limité par l'écoulement dans et autour des fibres ainsi que dans module et par le colmatage. Le double bioréacteur a membrane étudié dans cette thèse, de par son fonctionnement, alterne les cycles de filtration et rétrofiltration (ou rétrolavage), limitant ainsi en partie le colmatage. Ce travail de thèse s'est donc attaché à approfondir la con
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23

Sarrouj, Hiba. "DNP/solid state NMR probehead for the investigation of oriented membranes." Phd thesis, Université de Strasbourg, 2014. http://tel.archives-ouvertes.fr/tel-01038015.

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Helical membrane proteins comprise one third of the expressed proteins encoded in a typical genome. Other membrane proteins are typically beta sheets. Their function varies from pore formation, signaling to antimicrobial activity. They are also capable of transporting large cargo such as proteins or nucleic acids across the cell membrane. Recently, peptides have emerged as promising tools in drug delivery. Membrane proteins can be synthesized chemically or expressed and isotopically labeled in bacteria, isolated, purified and reconstituted into fully hydrated lipid bilayers. The bilayer orient
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24

Saad, Ahmad. "Les tannins du vins et les lipides de la bouche et du bol alimentaire : vers une modification des marqueurs du goût. Une approche moléculaire et sensorielle." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0879/document.

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Les tannins sont des polymères de polyphénols présents en quantité significative dans le vin rouge, et responsables de l’astringence et de l’amertume. L’astringence est une sensation de sècheresse et de rugosité en bouche résultant d’une forte interaction entre les tannins et les protéines de la salive impliquées dans la lubrification de la cavité buccale. L’amertume, quant à elle, est un goût stricto sensu résultant de l’interaction spécifique des tannins avec les récepteurs du goût situés dans les papilles linguales. Des études récentes ont montré que les tannins sont susceptibles d’interagi
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Wheeler, Sophia. "Physical properties of mixed membranes explored using atomistic and coarse grained molecular dynamic simulations with enhanced sampling techniques." Thesis, University of Southampton, 2018. https://eprints.soton.ac.uk/425867/.

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Studies of three different, but interlinked, aspects of membrane properties are presented here. First an analysis of both the lyotropic and thermotropic phase transitions of a phospholipid bilayer using the ELBA1.0 forcefield. This is believed to be the first time such transitions (including the rippled gel phase) have been observed using a coarse grained (CG) forcefield not specifically parameterised to do so. Further, analysis via enhanced sampling methods of the relative free energies of the phases is presented. These analyses confirm the enormous effects comparatively small changes to a fo
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26

Ghasemalizadeh, Farid [Verfasser], Philippe [Akademischer Betreuer] Bastiaens, and Leif [Gutachter] Dehmelt. "Recursive interaction between encapsulated dynamic microtubule asters and deformable membranes / Farid Ghasemalizadeh ; Gutachter: Leif Dehmelt ; Betreuer: Philippe Bastiaens." Dortmund : Universitätsbibliothek Dortmund, 2019. http://d-nb.info/1213975972/34.

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Whitehead, L. "Computer simulation of biological membranes and membrane bound proteins." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297412.

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Zhang, Wenxiang. "Optimization of protein concentration from alfalfa juice by high shear rate dynamic filtration." Thesis, Compiègne, 2016. http://www.theses.fr/2016COMP2281/document.

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Les protéines extraites des feuilles de luzerne sont une source importante de protéines. La filtration membranaire, technologie de séparation respectueuse de l’environnement avec une productivité élevée et de faible coût a été utilisée pour séparer et concentrer les protéines des feuilles de luzerne à partir de leur jus. Cependant le phénomène du colmatage de la membrane qui réduit sérieusement le flux et la séparation des protéines est un facteur limitant important dans l'application de la filtration membranaire. Pour améliorer la récupération des protéines et amenuiser le phénomène du colmat
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Martin, Marving. "Robustesse de la dynamique moléculaire pour reproduire les interactions moléculaires dans les membranes biologiques." Electronic Thesis or Diss., Limoges, 2024. http://www.theses.fr/2024LIMO0119.

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Cette thèse soutient le programme de recherche et développement d'InSiliBio, une start-up de chimie théorique. Elle a pour but d’étudier les interactions entre les xénobiotiques et les membranes biologiques, avec un accent particulier sur le stratum corneum de la peau. Cette couche externe de la peau offre une matrice lipidique essentielle à la régulation de la perméabilité et à la protection des tissus sous-jacents. Pour ce faire, des simulations de dynamique moléculaire (DM) ont été menées pour quantifier les interactions non covalentes associées au synergisme entre antioxydants, au sein des
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30

De, Vecchis Dario. "Gaining insights into mitochondrial membrane fusion through a structural and dynamic atomistic model of the mitofusin Fzo1p." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCC001.

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Les mitochondries sont des organites dynamiques dont la morphologie dépend de l’équilibre fusion/fission de leurs membranes. Ce processus essentiel à la survie cellulaire est nommé dynamique mitochondriale et sa dérégulation est associée à des troubles neurologiques. Cependant les mécanismes précis régissant la dynamique mitochondriale ne sont pas élucidés. Cette thèse porte sur la protéine Fzo1p, une grande GTPase de la superfamille des Dynamin-related-Protein. C’est un élément clé impliqué dans la fusion mitochondriale de la membrane externe de la levure. Sa structure et sa dynamique ont été
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Sadler, Emma Elizabeth. "Single-molecule fluorescence studies of KirBac1.1." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:214fcd74-7384-4ade-ac17-7cac5c44a05c.

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Inwardly rectifying potassium (Kir) channels are essential for controlling the excitability of eukaryotic cells, forming a key part of the inter-cellular signalling system in multi-cellular organisms. However, as prokaryotic (KirBac) channels are less technically challenging to study in vitro and have been shown to be directly homologous to eukaryotic channels, they are often studied in lieu of their mammalian counterparts. A vital feature of Kir and KirBac channels is their mechanism for opening and closing, or their gating: this study predominantly features observations of open and/or closed
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Dietrich, Undine [Verfasser], Josef Alfons [Akademischer Betreuer] Käs, Josef Alfons [Gutachter] Käs, and Helmuth [Gutachter] Möhwald. "Structural and dynamic studies of MARCKS interaction with PIP(2) containing lipid membranes / Undine Dietrich ; Gutachter: Josef Alfons Käs, Helmuth Möhwald ; Betreuer: Josef Alfons Käs." Leipzig : Universitätsbibliothek Leipzig, 2011. http://d-nb.info/1237895707/34.

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33

Nigam, Poonam. "Interaction of water-soluble surfactants with self-assembled lipid monolayers at the vapor-liquid interface equilibrium and dynamic phenomena /." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1157987838.

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34

Duncan, Anna Louise. "Coarse-grained molecular dynamics simulations of mitochondrial membrane proteins." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648455.

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35

Berrod, Quentin. "Relation structure - transport dans des membranes et matériaux modèles pour pile à combustible." Phd thesis, Université de Grenoble, 2013. http://tel.archives-ouvertes.fr/tel-00981913.

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L'optimisation des performances d'une pile à combustible (PEMFC) requiert la compréhension microscopique des mécanismes de transport de l'eau et du proton confinés au sein de la membrane électrolyte polymère. La membrane est un matériau nanostructuré chargé, caractérisé par une dynamique de l'eau et du proton complexe et multi-échelle étroitement corrélée à la morphologie confinante. Nous nous sommes intéressés à la relation structure - transport dans i) L'Aquivion, un ionomère perfluorosulfonique récent présentant de bonnes performances en pile, ii) des systèmes " modèles " auto-assemblés de
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36

Costello, Michael John School of Chemical Engineering &amp Industrial Chemistry UNSW. "SHELL-SIDE FLUID DYNAMICS AND MASS TRANSFER THROUGH HOLLOW FIBRE MEMBRANE MODULES." Awarded by:University of New South Wales. School of Chemical Engineering and Industrial Chemistry, 1995. http://handle.unsw.edu.au/1959.4/17042.

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There is a considerable volume of work available in literature which suggests that the performance of axial-flow hollow fibre membrane modules is limited by poorly distributed flow through the shell-side. This study was commissioned to examine the distribution of shell-side flow and its effect on mass transfer and to compare the performance measured by the axial-flow configuration to that obtained by a commonly used alternative known as the helically-wound module design. Laminar flow and mass transfer models have been developed to examine performance through axial-flow hollow fibre modules.
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Trochmann, Jose Luiz Lino. "Simulação atomistica como ferramenta para investigação dos mecanismos de difusão : coeficientes de autodifusão de gases simples em matriz polimerica." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266175.

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Orientador: Sergio Persio Ravagnani<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-07T03:49:14Z (GMT). No. of bitstreams: 1 Trochmann_JoseLuizLino_D.pdf: 1070584 bytes, checksum: 3407aee7ad6d88d9de0a1326aaf3d29d (MD5) Previous issue date: 2006<br>Resumo: Neste trabalho de tese foi realizado um estudo do potencial de predição de propriedades de transporte em matrizes poliméricas de poli - imidas, utilizando a simulação dinâmica molecular de gases simples como Oxigênio, Nitrogênio e Dióxido de Carbono. A proprieda
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Luna, Escalante Juan Camilo. "Spatio-temporal dynamics of intercellular Notch signaling: a modeling approach." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/400610.

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Intercellular signalling is a mechanism by which cells communicate and mediate coordinated responses. In this Thesis we perform theoretical and computational analyses to evaluate spatio-temporal organizations that can arise in developing embryos through juxtacrine signalling mediated by Notch receptor. Juxtacrine signalling is a type of intercellular communication in which adjacent cells mutually interact through membrane-attached proteins (receptors and ligands). In the case of Notch signalling, the ligands are regulated by the signalling, establishing a feedback loop on the activation of the
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Woo, Sahng Hyuck. "Membranes composites acide perfluorosulfonique (PFSA)/argile pour un fonctionnement à faible humidité relative et haute température des piles à combustible à membrane échangeuse de protons (PEMFC)." Thesis, Paris Sciences et Lettres (ComUE), 2019. http://www.theses.fr/2019PSLEM033.

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Cette thèse introduit de nouvelles membranes électrolytiques pouvant fonctionner à faible humidité relative (inférieure à 50%) et à une température intermédiaire, c'est-à-dire 90°C voire au-delà. Plus spécifiquement, la thèse tire profit de l'hygroscopicité de la morphologie d’argiles naturelles, lasépiolite microfibreuse et l’halloysite tubulaire . Ces nanoargiles ont été intégrées à des suspensions de Nafion® ou Aquivion pour préparer des membranes composites. Elles ont été fonctionnalisées et prétraitées pour les rendre conductrices protoniques et améliorer leur compatibilité avec les matri
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Al-Izzi, Sami. "Dynamics of lipid membrane tubes." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS674.

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Les tubes membranaires sont des structures omniprésentes dans les cellules, et la compréhension de leur dynamique et de leur morphologie est d'une importance cruciale pour la biophysique cellulaire. Cette thèse aborde plusieurs aspects de la dynamique des tubes membranaires dans des situations où ils sont déséquilibrés par divers processus inspirés par des phénomènes biologiques. Nous analysons le gonflement de tubes due à des pompes ioniques entraînant une différence de pression osmotique, ainsi que les instabilités qui en résultent. Ceci est inspiré par la structure d'un organelle appelé le
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Tarazaga, Pablo Alberto. "Dynamics and Control of a Pressurized Optical Membranes." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/28727.

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Optical membranes are currently pursued for their ability to replace the conventional mirrors that are used to correct wave front aberration and space-based telescopes. Among some of the many benefits of using optical membranes, is their ability to considerably reduce the weight of the structure. As a secondary effect, the cost of transportation, which is of great interest in space applications, is reduced as well. Given the low density of these thin-film membranes, the lower end dynamics play a greater significant role than their rigid plate-like counterparts in achieving functional mirrors
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Kiselev, Vladimir. "Computational study of electrostatic contribution to membrane dynamics." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5751.

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Electrostatics plays a crucial role in the membrane biology. Negatively charged lipids (such as PS, PA and PIP2) are subject to redistribution under the action of electrostatic forces during various signalling events. Membrane recruitment of multiple signalling proteins (such as MARCKS or Src kinase) is often maintained by positively charged polybasic domains (PD). Even though adsorption of these proteins to the cellular membrane has been extensively investigated, very little is known about how electrostatic interactions contribute to their membrane lateral dynamics. This thesis presents an in
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Witkowski, Thomas, Rainer Backofen, and Axel Voigt. "The influence of membrane bound proteins on phase separation and coarsening in cell membranes." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-139226.

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A theoretical explanation of the existence of lipid rafts in cell membranes remains a topic of lively debate. Large, micrometer sized rafts are readily observed in artificial membranes and can be explained using thermodynamic models for phase separation and coarsening. In live cells such domains are not observed and various models are proposed to describe why the systems do not coarsen. We review these attempts critically and show within a phase field approach that membrane bound proteins have the potential to explain the different behaviour observed in vitro and in vivo. Large scale simulatio
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Zheng, Yu Zi. "Dynamic composition of membrane microdomains." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42789.

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Lipid rafts are cholesterol enriched membrane microdomains involved in many cellular functions. Caveolae are a sub-type of lipid rafts that are smooth invaginations of the plasma membrane (PM) whose formation requires caveolin-1 (Cav1). Here, we determined the lipid rafts and caveolae proteome from various cells in an unbiased manner and examined the dynamic raft proteome change during Salmonella infection using quantitative proteomics. In chapter 2, we approach the status of mitochondrial proteins in detergent-resistant membrane (DRM) preparations by employing Stable Isotope Labeling by Amino
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Roengpithya, Chayaporn. "Membrane enhanced dynamic kinetic resolution." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438187.

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Parrett, Mark. "Membrane enhanced dynamic kinetic resolution." Thesis, University of Warwick, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441625.

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Witkowski, Thomas, Rainer Backofen, and Axel Voigt. "The influence of membrane bound proteins on phase separation and coarsening in cell membranes." Royal Society of Chemistry, 2012. https://tud.qucosa.de/id/qucosa%3A27814.

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A theoretical explanation of the existence of lipid rafts in cell membranes remains a topic of lively debate. Large, micrometer sized rafts are readily observed in artificial membranes and can be explained using thermodynamic models for phase separation and coarsening. In live cells such domains are not observed and various models are proposed to describe why the systems do not coarsen. We review these attempts critically and show within a phase field approach that membrane bound proteins have the potential to explain the different behaviour observed in vitro and in vivo. Large scale simulatio
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Bertot, Laëtitia. "Le rôle des protéines courbant les membranes dans l’endocytose indépendante de la clathrine suivie par le récepteur de l’interleukine 2." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS570/document.

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L’endocytose permet l’internalisation d’éléments présents dans le milieu extracellulaire tels que les nutriments. Ce processus prend place dans la membrane plasmique. Les courbures de la membrane jouent un rôle essentiel dans l’endocytose pour générer une invagination initiale, un puits, puis une vésicule qui se sépare ensuite de la membrane plasmique pour fusionner avec les compartiments intracellulaires. Il existe plusieurs voies d’endocytose qui peuvent être classées selon des critères tels que la taille des vésicules produites, la médiation par un récepteur ou la présence d’un manteau reco
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Gudejko, Heather F. M. "Membrane Dynamics During Cytokinesis." Thesis, Boston College, 2013. http://hdl.handle.net/2345/3781.

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Thesis advisor: David R. Burgess<br>Cytokinesis is the final step in cell division, culminating in the formation of two daughter cells from a single mother cell. Previous studies from our lab have shown that lipid rafts are dynamic during cytokinesis in sea urchin embryos, migrating into the ingressing cleavage furrow then moving back outwards towards the poles prior to abscission. Here, I quantitated the mobility of GM1, a ganglioside enriched in lipid rafts, using cholera toxin subunit B (CTB). Despite previous observations of raft movement during cell division, I have found lipid rafts to b
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Morlot, Sandrine. "Dynamin-Mediated Membrane Fission." Paris 7, 2012. http://www.theses.fr/2012PA077136.

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La cellule eukaryote est organisée en plusieurs compartiments, appelés organelles, délimités par des membranes; La fission des membranes est nécessaire pour le transport intracellulaire entre organelles. L'endocytose est un mécanisme de transport depuis la membrane plasmique vers les autres organelles. La Dynamine est une guanosine triphosphatase (GTPase) impliquée dans la fission des vésicules pendant l'endocytose médiée par la Clathrine. Elle polymerise en hélice au coup des bourgeons endocytiques. Après hydrolyse du GTP, la structure de l'hélice est modifiée : le rayon interne diminue de 10
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