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Artykuły w czasopismach na temat „Dyskeratosis Follicularis”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Wollina, Uwe, Gesina Hansel, Erich Kostler, and Jaqueline Schonlebe. "Glabellar pomade crust mimicking dyskeratosis follicularis." Journal of Cosmetic Dermatology 5, no. 1 (2006): 58–60. http://dx.doi.org/10.1111/j.1473-2165.2006.00224.x.

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Ferizi, Mybera, Antigona Begolli-Gerqari, Bostjan Luzar, Fisnik Kurshumliu, and Mergita Ferizi. "A Rare Clinical Presentation of Darier’s Disease." Case Reports in Dermatological Medicine 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/419797.

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Darier’s disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules, primarily affecting seborrheic areas on the head, neck, and thorax and less frequently on the oral mucosa. When oral manifestations are present, the palatal and alveolar mucosae are primarily affected. They are usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions are presented as suprab

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Nevozinskaya, Z. A., E. V. Denisova, L. R. Sakaniya, A. L. Piruzyan, and I. M. Korsunskaya. "Uncommon dermatological disorders: dyskeratosis follicularis (Darier's disease)." Dermatology Suppl. Consilium Medicum, no. 3 (2019): 22–23. http://dx.doi.org/10.26442/24143537.2019.3.190498.

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Oster-Schmidt, Claus, Markus Stücker, and Peter Altmeyer. "Dyskeratosis follicularis - erfolgreiche Therapie mit lokalem Retinoid." Der Hautarzt 51, no. 3 (2000): 196–99. http://dx.doi.org/10.1007/s001050051104.

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Manoja, K. G. D., B. S. M. S. Siriwardena, P. R. Jayasooriya, D. J. L. Siriwardane, and W. M. Tilakaratne. "A Rare Clinical Presentation of Intraoral Darier's Disease." Case Reports in Pathology 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/181728.

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Darier's disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules primarily affecting seborrheic areas on the head, neck, thorax, and less frequently the oral mucosa. When oral manifestations are present, the palatal and alveolar mucosae are primarily affected. They usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions present as suprabasal clefts in th

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6

Jörg, B., H. Erhard, and A. Rütten. "Eine hämorrhagische akrale Verlaufsformen der Dyskeratosis follicularis Darier." Der Hautarzt 51, no. 11 (2000): 857–61. http://dx.doi.org/10.1007/s001050051230.

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Zeglaoui, F., I. Zaraa, B. Fazaa, et al. "Dyskeratosis follicularis disease: case reports and review of the literature." Journal of the European Academy of Dermatology and Venereology 19, no. 1 (2005): 114–17. http://dx.doi.org/10.1111/j.1468-3083.2004.01096.x.

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Khlebnikova, A. N., A. V. Gurovich, E. V. Zenkevich, G. E. Bagramova, O. V. Dorokhina, and A. V. Molochkov. "Isolated lesion of inguinal folds and scrotum in dyskeratosis follicularis." Russian Journal of Clinical Dermatology and Venereology 23, no. 2 (2024): 129. http://dx.doi.org/10.17116/klinderma202423021129.

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Karagiannidis, Ioannis, Martina Brunner та Christos C. Zouboulis. "Exacerbation of Darier Disease under Interferon-α-2a Therapy with Clinical Signs of Lichen Nitidus". Case Reports in Dermatology 8, № 2 (2016): 218–23. http://dx.doi.org/10.1159/000446693.

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Darier disease/dyskeratosis follicularis is a genodermatosis characterized by brown, oily keratotic papules and plaques in the seborrheic areas of the face and chest. Responsible for the disease are mutations in the ATP2A2 gene, encoding SERCA2, a calcium pump of the sarco-/endoplasmic reticulum. Mechanical trauma, heat, humidity, ultraviolet B radiation, oral corticosteroids and lithium are known trigger factors of the disorder. We report on a 48-year-old German woman with a flare-up of Darier disease under interferon-α-2a (IFNα-2a) therapy with clinical signs of lichen nitidus. Due to the fu

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10

Raj, A. Thirumal, Kamran Habib Awan, Shankargouda Patil, Peter Morgan, and Saman Warnakulasuriya. "Oral Warty Dyskeratoma—A Systematic Review of the Literature." Diagnostics 12, no. 5 (2022): 1273. http://dx.doi.org/10.3390/diagnostics12051273.

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Objective: To systematically review the clinicopathological features of oral warty keratoma based on published literature. Materials and Methods: PubMed and Scopus databases were searched for reports of oral warty dyskeratoma. Of the 52 identified articles, only 25 articles (43 cases) satisfied the selection criteria (case report/series in the English language reporting clinicopathologically diagnosed oral warty dyskeratoma/oral focal acantholytic keratosis/oral isolated dyskeratosis follicularis in humans). Risk of bias was assessed using the Joanna Briggs institute critical appraisal checkli

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11

Rijzewijk, J. J., H. Groenendal, P. Van Erp, F. W. Bauer, and W. A. Van Vloten. "Cell kinetics in skin disorders with disturbed keratinization." Acta Dermato-Venereologica 72, no. 4 (1992): 256–58. http://dx.doi.org/10.2340/0001555572256258.

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A relatively simple immunohistochemical method was developed and used on cryostat sections. The monoclonal antibody Ki67 was used as marker for actively cycling cells and Pab601 for germinative cells. Counts were expressed as Ki67- or Pab601-positive cells/mm. In order to improve our understanding of the pathogenetic mechanisms in skin disorders with disturbed keratinization we have measured cell kinetic values in dyskeratosis follicularis, pemphigus benigna familiaris chronica, autosomal dominant ichthyosis vulgaris, X-linked recessive ichthyosis, atopic dermatitis and psoriasis and compared

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12

Adaskevich, Uladzimir P. "Darier's follicular dyskeratosis." Consilium Medicum 24, no. 8 (2022): 497–503. http://dx.doi.org/10.26442/20751753.2022.8.201830.

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Darier's follicular dyskeratosis (synonym: Dariers disease, DarierWhites disease) is a rare genetic disease with an autosomal dominant type of inheritance, which belongs to the group of acantholytic dermatoses and is characterized by a violation of keratinization processes with lesions of the skin, nails, mucous membranes of the oral cavity and genitals. Dariers disease is caused by a mutation in the ATP2A2 gene. This disrupts the operation of the SERCA2 pump and leads to a violation of calcium homeostasis in keratinocytes and a decrease in intercellular adhesion. Dariers disease is manifested

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13

Sgarbossa, Rayane Sol Amaral Silva, Gisele Vieira Sechi, Bruna Duarte Pacheco, et al. "The epidemiological and clinical aspects of Demodex injai demodicosis in dogs: a report of eight cases." Semina: Ciências Agrárias 38, no. 5 (2017): 3387. http://dx.doi.org/10.5433/1679-0359.2017v38n5p3387.

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The mite Demodex injai causes demodicosis, an uncommon, chronic, and recurrent parasitic dermatopathy in dogs. Demodicosis is characterized by an excessive proliferation of the Demodex injai mite in the pilosebaceous unit. Typically, demodicosis occurs in adults, and is associated with an underlying disease or a specific host immunodeficiency. Here, we describe the epidemiological, clinical, dermatological, and therapeutic aspects of Demodex injai demodicosis in dogs (n=8) at the Hospital Unit for Companion Animals of the Pontifical Catholic University of Paraná in Brazil. The affected dogs we

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14

Tkach, V. Ye, M. S. Voloshynovych, S. M. Romanchuk, G. Ye Girnyk, N. R. Matkovska, and N. V. Kozak. "Clinical cases of Darier-White follicular dyskeratosis." Medicni perspektivi 27, no. 3 (2022): 190–96. http://dx.doi.org/10.26641/2307-0404.2022.3.266006.

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Follicular dyskeratosis (Darier-White disease) is a hereditary skin disease that is extremely rare in medical practice, so errors in its diagnosis can occur. It was first described in 1889 by two scientists (independently of each other), Ferdinand-Jean Darier and James White. The disease is inherited in an autosomal dominant pattern with variable gene penetrance. The main cause of this pathological process is a mutation of the ATP2A2 gene, located in the long arm of chromosome 12. Both men and women are affected with the same probability, but clinical manifestations are more severe in males. I

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15

Tkach, V.Ye., M.S. Voloshynovych, S.M. Romanchuk, G.Ye. Girnyk, N.R. Matkovska, and N.V. Kozak. "Clinical cases of Darier-White follicular dyskeratosis." Medicni perspektivi 27, no. 3 (2022): 190–96. https://doi.org/10.26641/2307-0404.2022.3.266006.

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Follicular dyskeratosis (Darier-White disease) is a hereditary skin disease that is extremely rare in medical practice, so errors in its diagnosis can occur. It was first described in 1889 by two scientists (independently of each other), Ferdinand-Jean Darier and James White. The disease is inherited in an autosomal dominant pattern with variable gene penetrance. The main cause of this pathological process is a mutation of the ATP2A2 gene, located in the long arm of chromosome 12. Both men and women are affected with the same probability, but clinical manifestations are more severe in males. I

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16

Martynov, A. A., Yu I. Matushevskaya, O. R. Katunina, et al. "Follicular vegetative dyskeratosis complicated with a secondary infection." Vestnik dermatologii i venerologii 87, no. 4 (2011): 64–69. http://dx.doi.org/10.25208/vdv1043.

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A patient with a rare form of dermatosis, follicular vegetative dyskeratosis (Darier-White disease), was under observation. Particular features of the case under examination are described: prevalent skin eruptions with affected mucous coats of the oral cavity; pathologic process complicated with a secondary infection. The efficacy of neotigason, a drug belonging to the group of synthetic retinoids, was demonstrated.

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17

Yakovlev, Alexey B., and Ivan S. Maximov. "Chronicles of A.I. Pospelov Moscow Society of Dermatovenereologists and Cosmetologists (MSDC was founded on October 4, 1891). Bulletin of the MSDC № 1149." Russian Journal of Skin and Venereal Diseases 25, no. 5 (2023): 419–26. http://dx.doi.org/10.17816/dv112481.

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On October 18, 2022, the 1149th meeting of the A.I. Pospelov Moscow Society of Dermatovenerologists and Cosmetologists (MSDC) took place. The meeting was held in a face-to-face format. There were 128 participants in total. Accepted as a member of the MSDC 53 people. Two clinical cases are presented for discussion: trichoadenoma ― a rare benign follicular tumor consisting of strands of epithelial cells and keratinizing cysts embedded in the sclerotic stroma, and Dariers follicular dyskeratosis ― hereditary dermatosis characterized by the formation of follicular hyperkeratotic vegetative p

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18

Стрелкович, T. Strelkovich, Портнов, et al. "Puva Therapy and Isotretinoin in the Treatment of Patients with Follicular Dyskeratosis Darier." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 1–3. http://dx.doi.org/10.12737/5810.

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The paper presents data on the use of retinoid isotretinoin in the dose of 10mg in combination with PUVA therapy in treatment of patients with Darier&#180;s diseas. This combined method has a high therapeutic efficacy and this confirms the dynamics of the index of dermatological status and quality of life. This method has a preventive value and is accompanied by an increase of the remission. High safety of combined pharmacological and physiotherapeutic method is demonstrated.

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19

Torres, KaraMelissa Tiangco, and JacquelineM Junkins-Hopkins. "Cystic acantholytic dyskeratosis of the vulva: An unusual presentation of a follicular adnexal neoplasm." Indian Dermatology Online Journal 7, no. 4 (2016): 272. http://dx.doi.org/10.4103/2229-5178.185482.

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20

Silva, Luiz Augusto, and Luiza Conti. "Warty Dyskeratoma with involvement of multiple hair follicles in a dog." Brazilian Journal of Veterinary Pathology 16, no. 1 (2023): 60–63. http://dx.doi.org/10.24070/bjvp.1983-0246.v16i1p60-63.

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The warty dyskeratoma is a neoplasm of follicular origin, with uncommon incidence in veterinary medicine, and benign biological behavior. An excisional biopsy sample was received from a dog, female, Shih Tzu, 12 years old, from the left axillary region. Grossly, after section, green and friable multifocal areas were identified, streaked by solid white areas. Microscopically, the analysis revealed multifocal cystic structures, lined by stratified epithelium, with basal area including villous epithelial projections, toward the dermis, and the luminal region featured acantholysis and dyskeratosis

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21

Newman, M., P. Gerami, J. Guitart, et al. "Histological differentiation of skin toxicity between cetuximab, erlotinib and panitumumab (single ErbB1) and lapatinib (dual ErbB1/2) epidermal growth factor receptor inhibitors." Journal of Clinical Oncology 27, no. 15_suppl (2009): e20617-e20617. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e20617.

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e20617 Background: Epidermal growth factor receptor inhibition by monoclonal antibodies and tyrosine kinase inhibitors has demonstrated activity in solid tumors. However, blockade of EGFR in skin results in disabling skin toxicity that may lead to therapeutic dose modification or interruption. This study compares cutaneous histological alterations among four EGFR inhibitors (EGFRIs): cetuximab (C), erlotinib (E), lapatinib (L) and panitumumab (P). Methods: Punch skin biopsies from patients with papulopustular rash were collected from 8 patients per each EGFRI (n=32). Two dermatopathologists pe

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22

Chernysheva, Olga V., Olga V. Dorokhina, Albina N. Khlebnikova, and Elena V. Selezneva. "Adult-onset of Langerhans cell histiocytosis: a clinical case." Almanac of Clinical Medicine 49, no. 8 (2021): 558–63. http://dx.doi.org/10.18786/2072-0505-2021-49-064.

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Langerhans cell histiocytosis is mainly diagnosed in children, and its manifestation in adult age is quite uncommon. Skin rashes may be non-specific and mimic a number of dermatoses. Therefore, the clinical diagnosis is challenging and as a rule, such patients are misinterpreted and managed for other disorders by a dermatologist for some years. We present a clinical case of Langerhans cell histiocytosis with skin involvement in a 35-year female patient, who had been treated by a dermatologist for 2 years for pyoderma, seborrheic dermatitis, and skin fold candidiasis. Taking into account

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Gambichler, Thilo, Yi-Pei Lee, Ilske Oschlies, et al. "Antibody-Negative Paraneoplastic Autoimmune Multiorgan Syndrome (PAMS) in a Patient with Follicular Lymphoma Accompanied by an Excess of Peripheral Blood CD8+ Lymphocytes." Current Oncology 29, no. 4 (2022): 2395–405. http://dx.doi.org/10.3390/curroncol29040194.

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Paraneoplastic autoimmune multiorgan syndrome (PAMS) is a life-threatening autoimmune disease associated with malignancies. Here, we present a patient initially misdiagnosed with “chronic” Stevens–Johnson syndrome. Over a year later, the patient was diagnosed with stage IV follicular lymphoma and treated with an anti-CD20 antibody. At this time, his skin condition had significantly worsened, with erythroderma and massive mucosal involvement, including in the mouth, nose, eyes, and genital region. Histopathology revealed lichenoid infiltrates with interface dermatitis, dyskeratoses, necrotic ke

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Orpin, Sid, and Bhavnisha Patel. "BI30 An extensive follicular eruption in a transplant recipient." British Journal of Dermatology 191, Supplement_1 (2024): i152. http://dx.doi.org/10.1093/bjd/ljae090.318.

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Abstract A 46-year-old woman, who had been a patient with poorly controlled type 1 diabetes since age 18 years, received a combined pancreas and renal transplant in 2020. She was taking tacrolimus and mycophenolate as an immunosuppression regimen and presented with a 6-month history of an extensive rash. On examination, there was a widespread, symmetrical eruption affecting face, trunk and limbs consisting of folliculocentric pigmented keratinous papules. On the face and trunk in particular, these demonstrated a spiny appearance. Clinically, this was considered to be trichodysplasia spinulosa

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Shatokhina, E. A., A. G. Turkina, E. Yu Chelysheva, et al. "Specificity of dermatological adverse events of BCR-ABL tyrosine kinase inhibitors and their effect on quality of life of patients with chronic myeloid leukemia." Medical alphabet, no. 6 (June 16, 2020): 72–76. http://dx.doi.org/10.33667/2078-5631-2020-6-72-76.

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Introduction. BCR-ABL tyrosine kinase inhibitors are currently used to successfully treat chronic myeloid leukemia (CML). Drug therapy is carried out in a continuous daily mode throughout the patient’s life. Treatment with this group of drugs is associated with specific dermatological adverse events (dAE), which can lead to a change in the regimen of effective, vital therapy for CML patients.Purpose. To study the characteristics of dermatological adverse events, the severity and influence on the quality of life of BCR-ABL tyrosine kinase inhibitors.Patients and methods. The observational study

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Han, Chieun, Shakir Karim, and Stephen Orpin. "Poster presentationsDP11 Bright, eosinophilic intracytoplasmic inclusion bodies: a rare presentation of acquired epidermodysplasia verruciformis with widespread human papillomavirus infection in a transplant recipient." British Journal of Dermatology 191, Supplement_1 (2024): i111—i112. http://dx.doi.org/10.1093/bjd/ljae090.233.

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Abstract Acquired epidermodysplasia verruciformis (EV) is an uncommon dermatological condition exclusively observed in immunosuppressed individuals. Clinically, it is characterized by hyperpigmented papules resembling flat warts, brown–orange pityriasis versicolor-like macules and patches, or, in some instances, lesions mimicking seborrhoeic keratoses. Historically, it has been linked to patients infected with HIV, with only a few cases reported in association with organ transplantation worldwide. We present the case of a 46-year-old Afro-Caribbean woman with a history of poorly controlled typ

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O'Toole, Donal, and Merl F. Raisbeck. "Pathology of Experimentally Induced Chronic Selenosis (Alkali Disease) in Yearling Cattle." Journal of Veterinary Diagnostic Investigation 7, no. 3 (1995): 364–73. http://dx.doi.org/10.1177/104063879500700312.

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Prolonged oral exposure of cattle to elevated dietary selenium (Se) in forage and seleniferous plants in seleniferous areas of the western United States is associated historically with 2 clinical syndromes: alkali disease and “blind staggers.” The potential for Se-induced disease in cattle and other species is considerable in areas with seleniferous shales, Se-accumulating plants, arid climates, and alkaline soils. These 2 Se-associated conditions were defined in the 1930s and 1940s, and the nosology of blind staggers is questionable. Seventeen yearling steers fed 0.15, 0.28, and 0.8 mg Se/kg

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Holsen, Dag Sollesnes, and Anne Christine Johannessen. "Sykdommer som affiserer hud og munnslimhinne." Den norske tannlegeforenings Tidende 116, no. 6 (2006). http://dx.doi.org/10.56373/2006-6-5.

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Epidermolysis bullosa-sykdommene Pseudoxanthoma elasticum Acrodermatitis enteropatica Ektodermal dysplasi-sykdommer Dyskeratosis follicularis Dyskeratosis congenita Ehlers-Danlos’ syndrom Incontinentia pigmenti Pachyonychia congenita

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Jalil, A. A., R. B. Zain, and der Waal I. van. "Darier disease: a case report." Elsevier, January 1, 2005. https://doi.org/10.5281/zenodo.811199.

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Darier disease, also known as keratosis follicularis, dyskeratosis follicularis, and benign dyskeratosis, is a rare disorder of keratinisation that primarily affects the skin and, to a lesser extent, the oral mucosa. It was described independently by both Darier and White in 1889. It has a prevalence of 1:100,000 of the population and is inherited as an autosomal dominant trait.1 The age of onset is childhood or adolescence. Patients usually present with multiple small firm reddish-brown papules on the forehead, scalp, neck, shoulders, chest, and limbs. Other cutaneous signs include punctate k

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Wulf, H. C., and S. R. Wiegell. "Dyskeratosis follicularis cured by superficial radiotherapy: long‐term follow‐up of 10 patients." Journal of the European Academy of Dermatology and Venereology, November 12, 2020. http://dx.doi.org/10.1111/jdv.16957.

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Hanna, N., M. Lam, P. Fleming, and C. Lynde. "Therapeutic Options for the Treatment of Darier’s Disease: A Comprehensive Review of the Literature." Journal of Cutaneous Medicine and Surgery, November 28, 2021, 120347542110584. http://dx.doi.org/10.1177/12034754211058405.

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Darier’s disease (also known as keratosis follicularis or dyskeratosis follicularis) is an autosomal dominant inherited disorder which manifests as hyperkeratotic greasy papules in the first or second decade of life. Aside from symptom management and behavioral modifications to avoid triggers, there are currently no validated treatments for Darier’s disease (DD). However, a variety of treatments have been proposed in the literature including retinoids, steroids, vitamin D analogs, photodynamic therapy, and surgical excision. The purpose of this review article is to identify therapeutic options

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Dr, Muhammad Omer Dr Izhar Rashid Dr Shariq Mehmood. "HISTOPATHOLOGICAL STUDY AND CLINICAL PRESENTATION OF DARIER'S DISEASE." April 22, 2020. https://doi.org/10.5281/zenodo.3762269.

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<em>Darier's disease is infrequent, inherited autosomal dominant disease of the skin categorised by intense brownish keratotic papules in the palmar fossa, nail dystrophy and seborrheic parts of the body. The disease is usually aggravated by the exposure to sunlight, heat and sweating.</em> <strong><em>Aim: </em></strong><em>The purpose of this analysis was to determine the clinical profile, epidemiology and Darier’s disease histopathological characteristics.</em> <strong><em>Study Design: </em></strong><em>An Observational Study.</em> <strong><em>Place and Duration: </em></strong><e

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Lastre, Melba Gonzalez, Jojansy Rojo González, Isis Esther Martin Alonso, et al. "Darier's Disease: Case Report." Journal of Clinical Research and Clinical Trials 2, no. 2 (2023). http://dx.doi.org/10.59657/2837-7184.brs.23.009.

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Darier’s disease, or Darier-withe disease, also known as follicular dyskeratosis is an acantholytic and dyskeratotic Geno dermatosis. associated with intrinsic lesions of the inter keratinocyte adhesion systems; Usually begins between the first and second decade of life not affecting seborrheic areas with keratotic papule, very pruritic. There is no curative treatment. The psychosocial consequences caused by the appearance of the lesions and their chronic condition constitute the greatest concern. A 58-year-old female patient with a diagnosis of Darier’s disease based on clinical and family hi

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Drozhdina, Marianna, Varvara Bobro, and Elena Derpalyuk. "DARIER`S FOLLICULAR DYSKERATOSIS. EXPERIENCE OF SUCCESSFUL THERAPY." Vestnik dermatologii i venerologii, April 24, 2024. http://dx.doi.org/10.25208/vdv9840.

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Darier-White's follicular dyskeratosis is an autosomal dominant hereditary dermatosis, which is based on pathological keratinization due to impaired adhesion between keratinocytes, manifested mainly in the form of hyperkeratotic follicular papules on seborrheic areas of the skin. Therapy of rare genodermatosis still presents difficulties in the tactics of choosing a treatment method for each individual patient. Currently, there are no regulated methods of treating this disease. The article presents a clinical case of Darier-White's follicular dyskeratosis and demonstrates a successful experien

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Cardoso, Caroline Passos, Herbert Ives Barretto Almeida, Nilma Antas Neves, Fabiola Leal, and Daniel Abensur Athanazio. "Darier disease, hypertrophic / vegetating type." Surgical and Experimental Pathology 5, no. 1 (2022). http://dx.doi.org/10.1186/s42047-022-00124-8.

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Abstract Background A hypertrophic / vegetating variant of Darier disease causing massive verruciform genital tumors is exceedingly rare. Case presentation A woman in her late 50s underwent wide resection of vulva and inguinal skin due to massive verruciform lesion. She had crusted / keratotic plaques with appearance of follicular keratosis keratosis (with a greasy, warty texture) in the back, neck, face, and extremities for 27 years. Previous biopsies from lesions elsewhere 27 years ago and along the years showed the same verruciform, pseudoepitheliomatous pattern, with no atypia. The diagnos

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Huang, Chelsea, Mason Runge, Steven M. Hrycaj, Paul W. Harms, Douglas R. Fullen, and May P. Chan. "Proliferating inverted follicular keratosis of genital skin: Case series of a challenging variant." Journal of Cutaneous Pathology, May 12, 2024. http://dx.doi.org/10.1111/cup.14644.

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AbstractBackgroundInverted follicular keratosis (IFK) is a benign cutaneous epithelial tumor typically presenting as a small papule on the head and neck. We have encountered deep endophytic tumors on genital skin with some characteristics of IFK but also atypical features, raising concern for squamous cell carcinoma (SCC).MethodsFour such tumors were identified in our database. Histopathologic analysis and ancillary studies were performed.ResultsAll patients were young women who presented with a solitary 0.5–1.0 cm lesion on the vulva, perineum, or inner buttock. Each showed a squamous prolife

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Manohar, Archana, Meryl Antony, Rajalakshmi Tirumalae, and Inchara Yeliur Kalegowda. "Darier disease: Histopathology revisited." Indian Journal of Pathology and Microbiology, March 25, 2024. http://dx.doi.org/10.4103/ijpm.ijpm_610_23.

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ABSTRACT Darier disease (DD) is a rare genodermatosis. Literature on this topic is overwhelmingly dominated by case reports with rare clinical presentations, which have mentioned the histopathologic features briefly. The aim of this study was to document the histopathology of DD. Skin biopsies diagnosed as Darier disease based on clinicopathologic correlation over 12 years were reviewed for various epidermal and dermal features. There were 16 patients included, who most commonly presented in the third decade, with slight female predilection. The most common clinical presentation was hyperpigme

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