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Artykuły w czasopismach na temat „Ear biopsy”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Hurst, David S., and Kjeld Fredens. "Eosinophil cationic protein in mucosal biopsies from patients with allergy and otitis media with effusion." Otolaryngology–Head and Neck Surgery 117, no. 1 (1997): 42–48. http://dx.doi.org/10.1016/s0194-59989770204-3.

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Nine patients with persistent middle ear effusion and allergy confirmed by skin testing were evaluated for eosinophils by histochemical staining of middle ear mucosal biopsy specimens for eosinophil cationic protein. The study was designed to determine whether eosinophils were present in the middle ear mucosa of these patients and whether the elevated levels of eosinophil cationic protein reported in effusion from patients with chronic otitis media with effusion and allergy might originate within the mucosa itself. Seven of nine patients with otitis media with effusion had eosinophil cationic

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2

Burgener, Kate R., Stuart S. Lichtenberg, Aaron Lomax, Daniel J. Storm, Daniel P. Walsh, and Joel A. Pedersen. "Diagnostic testing of chronic wasting disease in white-tailed deer (Odocoileus virginianus) by RT-QuIC using multiple tissues." PLOS ONE 17, no. 11 (2022): e0274531. http://dx.doi.org/10.1371/journal.pone.0274531.

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Chronic wasting disease (CWD) is a fatal prion disease affecting cervids (deer, elk, moose). Current methods to monitor individual disease state include highly invasive antemortem rectal biopsy or postmortem brain biopsy. Efficient, sensitive, and selective antemortem and postmortem testing of populations would increase knowledge of the dynamics of CWD epizootics as well as provide a means to track CWD progression into previously unaffected areas. Here, we analyzed the presence of CWD prions in skin samples from two easily accessed locations (ear and belly) from 30 deceased white-tailed deer (

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3

Kumar, Surender, Uma Garg, Naveen Sharma, Neha Salaria, and Deepak Verma. "Squamous cell carcinoma of tympano-mastoid region: a series of six cases." International Journal of Otorhinolaryngology and Head and Neck Surgery 4, no. 3 (2018): 874. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20181891.

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<p class="abstract">The malignancies of tympanomastoid region are very rare entity. These tumours are more common in elderly persons in 6th and 7th decade. Males are more commonly affected than females. Chronically discharging ears are considered as risk factor which may be due to metaplasia in the middle ear mucosa following prolonged chronic infection. The most common symptoms are long standing blood tinged ear discharge, severe nocturnal pain, rapidly growing polypoidal or granulomatous mass in EAC or middle ear, peripheral facial palsy and painless ulceration over pinna or EAC. CT sc

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4

Sharma, A. K., S. Chatterjee, and V. L. Sharma. "Primary B-cell lymphoma presenting as bilateral ear lobule swelling." Journal of Laryngology & Otology 121, no. 12 (2007): 1207–9. http://dx.doi.org/10.1017/s0022215107000709.

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AbstractWe report a rare case of primary B-cell lymphoma presenting as bilateral ear lobule swelling. A 56-year-old white man presented with a one-year history of painless swelling of both ear lobules. An excision biopsy confirmed B-cell lymphoma. Detailed systemic investigation confirmed the primary nature of the tumour. This tumour is rare in the ear lobule. A review of the English literature revealed no previously reported case of bilateral primary ear lobule involvement. Clinicians should be aware that this tumour can present as a primary in the ear lobules.

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5

Adelola, O. A., R. Fernandez, R. Ahmad, M. Leamy, and B. G. Moriarty. "Sarcoidosis of the external ear – literature review and report of a case." Journal of Laryngology & Otology 121, no. 3 (2006): 289–92. http://dx.doi.org/10.1017/s0022215106003902.

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External ear manifestations of sarcoidosis are rare. We review six cases in the literature and also report a case. The otolaryngologist plays an important role in making the diagnosis because of the ease of biopsy in all cases of sarcoidosis of the external ear.

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6

Lee, W. C., G. M. Weiner, and J. B. Campbell. "Should nasopharyngeal biopsy be mandatory in adult unilateral glue ear?" Journal of Laryngology & Otology 110, no. 1 (1996): 62–64. http://dx.doi.org/10.1017/s0022215100132736.

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AbstractUnilateral secretory otitis media is a recognized presenting feature of nasopharyngeal neoplasia. In the two cases presented, biopsy from the nasopharynx revealed an unsuspected underlying adenocarcinoma. The need to biopsy the normal looking post-nasal space is highlighted.

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7

Peter, Madeleine St, Athanasia Warnecke, and Hinrich Staecker. "A Window of Opportunity: Perilymph Sampling from the Round Window Membrane Can Advance Inner Ear Diagnostics and Therapeutics." Journal of Clinical Medicine 11, no. 2 (2022): 316. http://dx.doi.org/10.3390/jcm11020316.

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In the clinical setting, the pathophysiology of sensorineural hearing loss is poorly defined and there are currently no diagnostic tests available to differentiate between subtypes. This often leaves patients with generalized treatment options such as steroids, hearing aids, or cochlear implantation. The gold standard for localizing disease is direct biopsy or imaging of the affected tissue; however, the inaccessibility and fragility of the cochlea make these techniques difficult. Thus, the establishment of an indirect biopsy, a sampling of inner fluids, is needed to advance inner ear diagnost

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8

Reina, Carlos O'Connor, Maria Teresa Garcia Iriarte, Francisco Javier Barron Reyes, Ernesto Garcia Monge, Rafael Luque Barona, and Diego Gomez Angel. "When is a biopsy justified in a case of relapsing polychondritis?" Journal of Laryngology & Otology 113, no. 7 (1999): 663–65. http://dx.doi.org/10.1017/s0022215100144780.

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AbstractRelapsing polychondritis (RP) is a relatively rare rheumatic condition of unknown aetiology. It is characterized by recurrent episodic inflammation of cartilaginous structures (nose, ear and trachea). The clinical diagnosis of polychondritis can frequently be made with confidence in the absence of histological confirmation. A 61-year-old diabetic man, with bilateral relapsing aural inflammation, left ear deafness with tinnitus and pain at the sternocostal junctions is reported. After clinical diagnosis of relapsing polychondritis steroid therapy was started. An ear cartilage biopsy was

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9

Yong, Doh Jeing, Abd Majid Md Nasir, and Bee See Goh. "Middle Ear Carcinoma Masquerading as an Aural Polyp." Philippine Journal of Otolaryngology-Head and Neck Surgery 27, no. 2 (2012): 17–19. http://dx.doi.org/10.32412/pjohns.v27i2.523.

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Objective: To present a case of middle ear carcinoma masquerading as an aural polyp and describe our experience with the clinical presentation, management and outcome of an elderly patient with this pathology. Methods: Design: Case Report Setting: Tertiary Public Hospital Patients: One Result: A 63-year-old female presented with an aural polyp and preceding symptoms of inner ear disturbances followed by otorrhea and otalgia. CT scans revealed an erosive lesion occupying the entire middle ear cleft, external ear canal and mastoid cavity with involvement of inner st

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10

Thompson, Lester D. R. "Biopsy Interpretation of the Upper Aerodigestive Tract and Ear, 2nd edition (Biopsy Interpretation Series)." American Journal of Surgical Pathology 37, no. 10 (2013): 1632. http://dx.doi.org/10.1097/pas.0b013e3182a021b4.

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11

Perez-Ordonez, B. "Biopsy interpretation of the upper aerodigestive tract and ear." Journal of Clinical Pathology 62, no. 2 (2009): 192. http://dx.doi.org/10.1136/jcp.2008.059006.

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12

Gupta, Nandini, Divyanshu Sharma, and Darshan Parikh. "Tuberculous otomastoiditis: analysis of otological tuberculosis with intact tympanic membrane." International Journal of Otorhinolaryngology and Head and Neck Surgery 10, no. 1 (2024): 100–103. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20240067.

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In recent years extra pulmonary tuberculosis has more frequently been associated with mastoiditis in patients with immunodeficiency state. Although tuberculosis of the mastoid or otomastoiditis is a very rare complication of tuberculosis today, when occurs it may cause significant morbidity. Complications such as facial paralysis and permanent hearing loss may develop. Our purpose was to evaluate the differential findings of tuberculous otomastoiditis and evaluation of outcomes in patients undergoing surgery along with anti-tubercular therapy rather than patients receiving only anti-tubercular

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13

George, M., C. Ikonomidis, M. Pusztaszeri, and P. Monnier. "Primary meningioma of the middle ear: case report." Journal of Laryngology & Otology 124, no. 5 (2009): 572–74. http://dx.doi.org/10.1017/s0022215109991745.

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AbstractObjective:To report a rare case of primary meningioma of the middle ear.Method:We describe the case of a 55-year-old woman who presented with decreased hearing and fullness in the left ear, with a middle-ear mass. We also review the world literature regarding primary extracranial meningioma of the middle ear and its management.Results:Primary middle-ear meningioma, a rare clinical entity, was diagnosed in this patient based on an initial transmastoid biopsy. Magnetic resonance imaging with gadolinium enhancement excluded the presence of an intracranial component. Complete excision of t

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14

Adams, Mark, Catherine Smith, and Susanne Hampton. "Isolated Schneiderian papilloma of the middle ear cleft." BMJ Case Reports 12, no. 1 (2019): e228130. http://dx.doi.org/10.1136/bcr-2018-228130.

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A 60-year-old woman presented with pulsatile tinnitus in the left ear. MRI and CT imaging suggested a soft-tissue mass in the middle ear. Exploratory tympanotomy and biopsy confirmed Schneiderian (inverted) papilloma. Endoscopic and radiological assessment showed no evidence of sinonasal lesions. The patient proceeded to mastoid surgery with removal of the ossicles for disease clearance. The small number of cases published to date of isolated middle ear inverted papilloma suggest a high recurrence and malignant transformation rate and aggressive management is therefore warranted.

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15

Kakkar, Vikas, Chandni Sharma, Surender Bishnoi, Ankit Gulati, and Mohit Pareek. "Tuberculosis of Middle Ear." International Journal of Advanced and Integrated Medical Sciences 2, no. 2 (2017): 104–5. http://dx.doi.org/10.5005/jp-journals-10050-10086.

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ABSTRACT A 32-year-old female presented with a history of otorrhea and hearing loss in her right ear since 2 years. On examination, external auditory canal was found to be filled with polypoidal tissue along with mucopurulent discharge. Audiometry showed mixed hearing loss of 50, 55, and 60 dB with air-bone gap of 30, 35, and 40 dB at frequencies of 0.5, 1, and 2 kHz respectively. She was operated for the same, and biopsy was sent for histopathological examination, which showed granulomatous inflammation. The patient was treated with antituberculous therapy, and she responded fully to the trea

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16

Kabir, Iqbal Murshed, Ahmid Minhas Shumon, Kazi Atikuzzaman, Yeahyea Zaman, and Atiqur Rahman. "Simultaneous involvement of lungs, larynx and middle ear by tuberculosis -a rare case." Journal of Dhaka National Medical College & Hospital 17, no. 1 (2012): 53–55. http://dx.doi.org/10.3329/jdnmch.v17i1.12195.

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Simultaneous involvement of lungs, larynx and middle ear by tuberculosis is very rare. We present a rare case of simultaneous involvement of larynx and ear in a patient with pulmonary tuberculosis. A 17 years old male presented with fever and cough for 8 months, bilateral deafness for 5 months and hoarseness of voice for 3 months. The patient gave history of anorexia and progressive weight loss and history of close contact with tuberculosis patient. There were coarse crepitations on auscultation of both lungs. Indirect laryngoscopy revealed diffuse nodular swelling as well as thickening of the

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17

Żurek, Michał, Anna Rzepakowska, and Kazimierz Niemczyk. "Difficulties in clinical staging of external ear canal carcinoma– a case report." Polski Przegląd Otorynolaryngologiczny 7, no. 1 (2018): 30–35. http://dx.doi.org/10.5604/01.3001.0011.6697.

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Carcinoma of the external auditory canal (EAC) is known to be very rare with a rate of 1-6 per million people. It affects mostly people over the age of 50 regardless of gender. The most common type of carcinoma of EAC is squamous cell carcinoma (SCC). The aim of this paper is to present the case of a 56-year-old woman with carcinoma of EAC. She was admitted to otolaryngology clinic due to ear buzzing lasting for five months, periodic otorrhea and hearing deterioration in her right ear. In otoscopic examination a tumor in the right ear meatus was identified. It filled almost the entire canal. B

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18

Barry, Jonnae Y., Saranya Reghunathan, and Abraham Jacob. "Tympanosclerosis Presenting as Mass: Workup and Differential." Case Reports in Otolaryngology 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/9821493.

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Introduction. Tympanosclerosis is a commonly encountered entity within ENT clinics and primary care settings. Recognizing ear pathology is essential for correct management. Oftentimes the diagnosis is clear; however in certain cases further workup to rule out other more insidious disease processes is warranted.Case Report. We present a case of tympanosclerosis which presented as an ear mass without classic appearance of tympanosclerosis. Through imaging and biopsy the diagnosis of tympanosclerosis was made. The patient was treated surgically with good outcome.Discussion. Various ear pathologie

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19

Bosler, Edward M., Robert D. Evans, and Edward M. Schneider. "Biopsy of canine ear tissue for detection ofBorrelia burgdorferifollowingIxodes damminifeeding." FEMS Microbiology Letters 99, no. 2-3 (1992): 317–20. http://dx.doi.org/10.1111/j.1574-6968.1992.tb05588.x.

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20

Melchor, C., and J. C. Shotton. "Should nasopharyngeal biopsy be mandatory in adult unilateral glue ear?" Journal of Laryngology & Otology 110, no. 10 (1996): 996–97. http://dx.doi.org/10.1017/s0022215100135595.

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21

Fränzer, Jürgen-Theodor, and Holger Sudhoff. "Middle ear cholesteatoma." e-Neuroforum 16, no. 1 (2010): 1–8. http://dx.doi.org/10.1007/s13295-010-0001-2.

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AbstractCholesteatomas can originate at various sites on the temporal bone, which houses the middle ear among other structures. Distinction is made between three types of cholesteatoma: auditory canal, middle ear, and petrous apex. The most frequent type, middle ear cholesteatoma, can be subdivided into a congenital and an acquired form. A number of theories on the aetiology of this aggressive form of middle ear inflammation have been put forward and, in some cases, dismissed again.We investigated the role of bacterial infection as a trigger in the development of cholesteatomas. For this

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22

Beagles, Emma, and Allen Shih. "New tender, bleeding papule on the left ear." BMJ Case Reports 17, no. 1 (2024): e258101. http://dx.doi.org/10.1136/bcr-2023-258101.

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Chondrodermatitis nodularis helicis (CNH) is a painful, inflammatory condition that impacts the skin of the ear. It is commonly associated with pressure on the pinna causing a nodule that may have erythema, bleeding and exudate. We present a case of a woman in her 60s with a history of basal cell carcinoma who presented with a new tender spot on the antihelix of her left ear. The tenderness of the new spot forced her to switch from holding her phone to her left ear to using her right ear. A shave biopsy confirmed CNH and ruled out non-melanoma skin cancer. Although most prior cases report asso

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23

Boudinar, H., I. Horrane, Z. El hafi, et al. "Ceruminous Adenocarcinoma of the External Auditory Canal: A Case Report and Review of the Literature." SAS Journal of Medicine 11, no. 07 (2025): 719–22. https://doi.org/10.36347/sasjm.2025.v11i07.014.

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Background: Ceruminous gland adenocarcinoma of the external auditory canal (EAC) is an uncommon malignant tumor with nonspecific clinical features and often delayed diagnosis. Case Presentation: A 72-year-old woman had purulent otorrhoea of the right ear and ipsilateral facial paralysis. Otoscopy revealed a mass occupying the right EAC. CT scan result was cholesteatoma. Histopathology showed adenocarcinoma of ceruminous gland. The patient underwent wide surgical excision with adjuvant radiotherapy and has been in complete remission at 3 years. Conclusion: Early biopsy is emphasized in this cas

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24

Eryilmaz, A., M. Dagli, M. Cayonu, E. Dursun, and C. Gocer. "An aberrant internal carotid artery in the temporal bone presenting as a middle-ear mass: a case report." Journal of Laryngology & Otology 122, no. 9 (2007): 983–85. http://dx.doi.org/10.1017/s0022215107000199.

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AbstractObjective:To draw attention to the possibility of an aberrant internal carotid artery behind an intact tympanic membrane presenting as a middle-ear mass.Case:A 48-year-old female patient presented with a hearing impairment in her right ear that had started 10 years ago. Otoscopic examination revealed a retro-tympanic mass. A high resolution computed tomography scan of the temporal bone was performed that showed protrusion of the internal carotid artery into the middle ear. Magnetic resonance angiography provided excellent visualisation of the internal carotid artery. Finally, a diagnos

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25

Bhat, Manali, H. Vijayendra, Vinay Kumar Vijayendra, and Nilesh Mahajan. "Middle ear neuroendocrine tumour-case report of a rare tumour of the temporal bone." International Journal of Otorhinolaryngology and Head and Neck Surgery 9, no. 12 (2023): 981–83. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20233589.

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Several conditions are known to present as masses in the middle ear medial to an intact tympanic membrane. Reddish masses that blanch on seigelization are usually paragangliomas. Sometimes, a high rising jugular bulb or an aberrant carotid artery can also be seen. Whitish masses are usually congenital cholesteatomas, tympanosclerosis, cartilage grafts that have been surgically placed, and rarely middle ear adenomas (MEA). An elderly male presented with decreased hearing, which was revealed to be secondary to a pale mass in the middle ear, displacing the intact tympanic membrane laterally. He u

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26

Belhaj, N., R. Bencheikh, M. A. Benbouzid, L. Houssayni, and Essakalli Essakalli. "A dragging Externotitis Hiding Tuberculosis of the External Ear." Saudi Journal of Medical and Pharmaceutical Sciences 9, no. 10 (2023): 713–16. http://dx.doi.org/10.36348/sjmps.2023.v09i10.003.

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Tuberculosis of the ear is rare; we report the case of an 86-year-old patient, followed for a dragging otitis resistant to local and general treatment whose clinical picture mimicked malignant extern otitis but during the biopsy of the polyp of the external auditory canal revived the diagnosis.

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27

Rau, Akash, Anne Opalikhin, Kaitlin Kreuser, Richard Ashack, and Kurt Ashack. "Unusual Presentation of Marginal Zone Lymphoma." SKIN The Journal of Cutaneous Medicine 8, no. 3 (2024): 1532–36. http://dx.doi.org/10.25251/skin.8.3.9.

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Primary cutaneous B-cell lymphomas (pcBCLs) are non-Hodgkin lymphomas that present with exclusive cutaneous disease at the time of diagnosis. The lesions may be indolent, subtle, or waxing and waning, making the diagnosis challenging. The ear is an uncommon location, and its frequency of involvement remains unknown. A retrospective analysis of a single patient with primary cutaneous marginal zone lymphoma of the ear. The patient was a 44-year-old male who presented with erythematous tender nodules on the left superior posterior helix. Shave biopsy revealed mixed dermal lymphoid infiltrate with

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Saliba, Walid R., Lee H. Goldstein, George S. Habib, and Mazen S. Elias. "Sweet’s syndrome affecting the external auditory canal and tympanic membrane." Journal of Laryngology & Otology 118, no. 1 (2004): 48–49. http://dx.doi.org/10.1258/002221504322731637.

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We report a patient who developed left ear pain, dry cough, and fever. The external auditory canal was tender, swollen, erythematous and full of debris. Later the patient developed widespread tender and red skin nodules and pustules that subsequently coalesced to form plaques. Identical lesions developed also in the external auditory canal and the tympanic membrane of the affected ear. Skin biopsy showed dermal neutrophilia, compatible with the diagnosis of Sweet’s syndrome. Rapid improvement was achieved with prednisone after the failure of antibiotics.

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Agarwal, Mallika, Shirish Sahebrao Chandanwale, Devisha Agarwal, and Padmakar Rajabhau Bardapurkar. "Primary Temporal Bone Meningioma Extending into the Middle and External Ear – A Rare Case Report with Review of Literature." Indian Journal of Otology 30, no. 2 (2024): 131–33. http://dx.doi.org/10.4103/indianjotol.indianjotol_118_23.

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Primary temporal bone meningioma of the middle ear is relatively rare in clinical practice. It is difficult to distinguish it from otitis media with effusion or chronic otitis media owing to its similar clinical presentation. We report the case of a 73-year-old temporal bone meningioma extending to the middle ear as well as involving the external auditory canal. High-resolution computed tomography revealed the possibility of left chronic otomastoiditis. After debulking and biopsy, it turned out to be an extracranial meningioma.

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Kilgue, Alexander, Rayoung Kim, Lars-Uwe Scholtz, et al. "Window Coverage and Liquid Biopsy in the First-Line Therapy of Severe Sudden Sensorineural Hearing Loss." Brain Sciences 14, no. 11 (2024): 1154. http://dx.doi.org/10.3390/brainsci14111154.

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Introduction: Based on clinical practice guidelines, the application of corticosteroids as a first-line therapy is common. Although sudden sensorineural hearing loss (SSHL) etiology is primarily idiopathic, hearing loss can result from a perilymphatic fistula (PLF). Recent findings show evidence of a specific rate of PLF based on a cochlin-tomoprotein (CTP) detection test. Based on this rate of PLF treatment, the concepts of SSNHL need to be re-evaluated. The present study aimed to evaluate CTP in SSNHL patients and compare pre-surgical and post-surgical pure tone hearing thresholds after roun

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Bajpai, Sanchit, Sweekritha Bhat, Vijendra Shenoy S, and Praneetha Puvvula. "Intratemporal mucormycosis: a rare COVID-19 sequelae." BMJ Case Reports 16, no. 4 (2023): e250533. http://dx.doi.org/10.1136/bcr-2022-250533.

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A man in his 50s presented with a 2-month history of left ear discharge associated with hearing loss and weakness of left half of face since 15 days. The patient had no comorbidities, but he gave history of being treated for COVID-19 pneumonia 2 months ago post which he started experiencing left-sided aural symptoms. Clinical examination of ear revealed a subtotal perforation with multiple granulations in middle ear. Facial nerve examination revealed grade 3 lower motor neuron palsy. The biopsy of the granulations was sent to aid in diagnosis which later confirmed left ear mucormycosis. Otolog

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Bass, John Augustus, Tanya Gupta, Nick Saunders, and Philippe Bowles. "A cutaneous sensory nerve schwannoma occluding the external auditory canal." BMJ Case Reports 17, no. 11 (2024): e257007. http://dx.doi.org/10.1136/bcr-2023-257007.

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Schwannomas are benign tumours derived from Schwann cells of the peripheral nerve sheaths. A schwannoma arising in the external auditory canal (EAC) is rare, with few cases reported in the literature. These tumours present a unique challenge and should be considered when patients present with persistent ear symptoms in the absence of common otological pathology. We present a case of a man in his late 60s, referred to the otolaryngology team with unilateral conductive hearing loss and a right-sided EAC mass found on otoscopy. CT and MRI of the head and neck revealed a mass occluding the right E

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Khan, Hamad Dad, Sahil Kakar, Lisha McClelland, and Hayder Hussein. "Blastic plasmacytoid dendritic cell neoplasm: a rare external ear lesion presenting with leukaemia." BMJ Case Reports 17, no. 9 (2024): e260059. http://dx.doi.org/10.1136/bcr-2024-260059.

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Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive haematological malignancy, typically characterised by cutaneous lesions and bone marrow involvement. We present a unique case of a woman in her 70s, initially seen for a spontaneous swelling on her left external ear resembling a haematoma, which recurred after initial treatment, triggering further evaluation.Diagnostic challenges arose as the patient displayed positive markers for Myeloperoxidase (MPO) (p-ANCA), suggesting vasculitis. Dermatology considered various differential diagnoses, but imaging and tests ruled

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Carson, Henry J., Jeffrey S. Krivit, and Stanley G. Eilers. "Metastasis of Colonic Adenocarcinoma to the External Ear Canal: An Unusual Case with a Complex Pattern of Disease Progression." Ear, Nose & Throat Journal 84, no. 1 (2005): 36–38. http://dx.doi.org/10.1177/014556130508400113.

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We report on a patient who developed far-ranging metastases of adenocarcinoma of the colon that followed a gradual cephalad progression, including the right external ear canal, and led to hearing loss. The patient was a 63-year-old white male with stage III adenocarcinoma of the colon. After 2 years with metastases elsewhere, he developed hearing loss on the right side. Physical examination of the head and neck showed a mass in the external ear canal, and biopsy confirmed adenocarcinoma. After removal, the patient's hearing improved. This case is interesting not only because of the unusual met

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Söderman, M., M. Moersdorf, M. Lysdahl, and L. Mendel. "Otorrhagia from the “Aberrant Internal Carotid” Artery in the Middle Ear." Interventional Neuroradiology 3, no. 3 (1997): 231–38. http://dx.doi.org/10.1177/159101999700300305.

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Agenesis of the cervical portion of the internal carotid artery (ICA) may result in blood supply to the ipsilateral cerebral hemisphere being provided by an enlarged inferior tympanic branch of the ascending pharyngeal artery. This enlarged vessel, passing through Jacobson's canal and anastomosing with the likewise enlarged caroticotympanic branch of the ICA in front of the promontorium, may simulate a middle ear mass. We present five patients with this unusual anatomical variant, three of which underwent biopsy of what was believed to be a middle ear tumour. One patient experienced rupture of

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Berrocal, Jose Ramon Garcia, and Rafael Ramirez-Camacho. "Immune response and immunopathology of the inner ear: an update." Journal of Laryngology & Otology 114, no. 2 (2000): 101–7. http://dx.doi.org/10.1258/0022215001905021.

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Immune-mediated inner-ear disease includes clinical conditions associated with unilateral or bilateral rapidly progressive forms of sensorineural hearing loss. A systemic autoimmune disorder can be present in less than one-third of cases. Because of the lack of well defined detection methods to identify immune-mediated processes within the inner ear, and the fact that the human inner ear is not amenable to diagnostic biopsy, there has been great interest in developing animal models. Experimental models of sterile and virus-induced labyrinthitis support the participation of the immune system in

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Yu, Kwi Ju, Hye Bin Kim, and Beom Cho Jun. "A case of schwannoma in the middle ear cavity misdiagnosed as cholesteatoma." Journal of Korean Skull base society 18, no. 1 (2023): 63–67. http://dx.doi.org/10.55911/jksbs.23.0002.

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Schwannoma is slow-growing, benign neurogenic tumor arising from schwann cells and rarely occurs in the middle ear cavity. The origins of primary schwannoma in the middle ear are the facial nerve, chorda tympanic nerve, and Jacobson’s nerve. Only a few cases have been reported of sympa-thetic plexus of the internal carotid nerve as the origin of primary schwannoma. We present a case of a 62-year-old male patient who have had recurrent otitis media for 20 years and accompanied by pus like discharge, otalgia, and hearing loss. On otologic examination, we found whitish mass in the middle ear cavi

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Devita, Arleen, Fera Ibrahim, Sri Linuwih Susetyo Wardhani Menaldi, Angky Budianti, and Andi Yasmon. "Detection of Mycobacterium leprae using real-time PCR in paucibacillary leprosy patients with negative acid-fast bacilli smears." Medical Journal of Indonesia 28, no. 4 (2019): 351–7. http://dx.doi.org/10.13181/mji.v28i4.2643.

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BACKGROUND Leprosy is an infectious disease that is still a health problem worldwide, including in Indonesia. The clinical symptoms are similar to other skin diseases and it is difficult to establish a diagnosis for paucibacillary (PB) leprosy. Current serological and histopathological tests have limitations, especially in patients with negative acid-fast bacilli (AFB). Serological tests often give false-negative results, while histopathological results often consist of non-specific inflammation. Probe-based real-time polymerase chain reaction (RT-PCR) assays is an alternative test that may be

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Nicolay, Simon, Bert De Foer, Anja Bernaerts, Joost Van Dinther, and Paul M. Parizel. "Aberrant internal carotid artery presenting as a retrotympanic vascular mass." Acta Radiologica Short Reports 3, no. 10 (2014): 204798161455369. http://dx.doi.org/10.1177/2047981614553695.

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We report a case of a young woman with an aberrant right internal carotid artery (ICA) presenting as a retrotympanic reddish mass. This variant of the ICA represents the collateral pathway that is formed as a result of an embryological agenesis of the cervical segment of the ICA. The embryonic inferior tympanic artery is recruited to bypass the absent carotid segment. This hypertrophied vessel may be seen otoscopically and wrongfully considered to be a vascular middle ear tumor. Informing the otorhinolaryngologist of this important vascular variant not only obviates biopsy but also helps in ca

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Yamasaki, Alisa, Michael P. Wu, and Kevin S. Emerick. "Outcomes of Cartilage-Sparing Wide Local Excision for Primary Melanoma of the External Ear." OTO Open 4, no. 1 (2020): 2473974X2090312. http://dx.doi.org/10.1177/2473974x20903124.

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Objective To describe outcomes after cartilage-sparing wide local excision for primary melanoma of the external ear. Study Design Retrospective analysis of patients undergoing external ear melanoma excision using a cartilage-sparing approach at a university-based tertiary care center between 2010 and 2018. Setting University-based tertiary care center. Subject and Methods Chart review was performed for all patients over age 18 who were treated for melanoma of the external ear at Massachusetts Eye and Ear between 2010 and 2018. Patients with melanoma in situ or with melanomas in noncartilaginou

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Bruschini, Luca, Rachele Canelli, Christina Cambi, Giacomo Fiacchini, Stefano Berrettini, and Francesca Forli. "Middle Ear Neuroendocrine Adenoma: A Case Report and Literature Review." Case Reports in Otolaryngology 2020 (December 21, 2020): 1–5. http://dx.doi.org/10.1155/2020/8863188.

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Neuroendocrine adenomas of the middle ear are rare tumors that represent less than 2% of primary tumors of the ear. In this paper, we describe a case of a 40-year-old woman who developed neuroendocrine adenoma of the middle ear. The specific management strategy for this rare tumor is unclear; information in the available literature on the management of this tumor is varied. However, an extensive demolition seems to be the gold standard treatment for this tumor to avoid recurrence and regional metastases in the lymph node or distant metastases. For the present case, we performed an incisional b

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Rainsbury, P., A. Mitchell-Innes, H. Wilson, and M. Prior. "Aspergilloma of the middle ear mimicking necrotising otitis externa: case report." Journal of Laryngology & Otology 124, no. 11 (2010): 1209–11. http://dx.doi.org/10.1017/s0022215110001490.

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AbstractObjective:We report a case of a patient who presented with otalgia and facial nerve palsy secondary to an aspergilloma of the middle ear.Case report:A 72-year-old, diabetic man presented to the ENT department with a history of worsening right-sided otalgia, aural discharge and hearing loss, associated with a right-sided facial weakness. This was assumed to be secondary to malignant otitis externa, and treatment was commenced. Imaging showed soft tissue within the middle ear and no bony erosion. Surgical exploration and biopsy revealed an aspergilloma of the middle ear. The pre- and pos

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Huellner, M. W., M. Cousin, T. Linder, et al. "Melanoma of the middle ear: initial presentation, Fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography imaging and follow up." Journal of Laryngology & Otology 125, no. 5 (2011): 536–39. http://dx.doi.org/10.1017/s0022215110002872.

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AbstractBackground:We present a rare case of primary mucosal melanoma of the middle ear imaged with 18F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT).Method:Clinical, radiological, intra-operative and histological findings are discussed.Results:An 88-year-old woman presented with intermittent otorrhoea of the left ear for several months. Otoscopy revealed a livid protrusion of the tympanic membrane. Melanoma was not suspected initially, but was established on transmembranous biopsy. Pre-operative 18F-fluoro-2-deoxy-d-glucose positron emission tomography

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Morshed, AKM Amirul, Shahnoor Islam, Zakia Rahman, Helena Begum, and Syed Ahsan Ali. "A Case Report of Nasopharngeal Carcinoma in Children presented with rt. Neck Mass." Journal of Paediatric Surgeons of Bangladesh 4, no. 1 (2015): 32–35. http://dx.doi.org/10.3329/jpsb.v4i1.23934.

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Nasopharyngeal carcinoma is a rare disease in children. It present with mass in the nasopharynx or neck swelling. Recently a six year old boy was diagnosed as a case of NPC and treated with standard chemotherapy. The boy was presented with neck swelling, palatal palsy and ear discharge. The patient was diagnosed by lymph node biopsy and immunohistochemistry. The diagnosis was delayed for 4 months which usually occur in our country. He was diagnosed by lymph node biopsy and immunohistochemistry. He was treated with standard protocol based chemotherapy.J. Paediatr. Surg. Bangladesh 4(1): 32-35,

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Yousefian, Faraz, Liliana Espinoza, Sarah Berger, Sandra Osswald, and Frank Petr. "Tophaceous Gout on Ear Imitating Squamous Cell Carcinoma." SKIN The Journal of Cutaneous Medicine 6, no. 4 (2022): 321–23. http://dx.doi.org/10.25251/skin.6.4.9.

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We report a case of tophaceous gout occurring in a Hispanic 69-year-old immunocompetent man. The patient presented with a 0.8 cm pink, purple, and brown dome-shaped papule on the right superior helix of the ear. The lesion was tender to palpitation. A deep shave biopsy was performed and the histological findings demonstrated pseudoepitheliomatous hyperplasia overlying large dermal deposits of pink, hyalinized feathery material surrounded by mild granulomatous inflammation. This finding supported the diagnosis of tophaceous gout rather than the clinical findings imitating squamous cell carcinom

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Jakovljevic, Sasa, Nenad Arsovic, Novica Boricic, Darko Laketic, and Zoran Dudvarski. "Syringocystadenoma Papilliferum in the External Ear Canal." Archives of Iranian Medicine 25, no. 9 (2022): 658–60. http://dx.doi.org/10.34172/aim.2022.101.

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Out of all benign tumors of the ceruminous glands, syringocystadenoma papilliferum is the rarest and represents only 2% of cases. It is an extremely rare benign tumor that originates from modified apocrine sweat glands. The aim of this paper was to present, according to our findings, the 18th case of syringocystadenoma papilliferum in the external auditory canal, with a detailed review of its clinical, radiological and histomorphological characteristics. A 59-year-old man reported to our clinic due to a 5×5 mm papillomatous growth at the entrance to the right external auditory canal. Histopath

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Bittencourt, Achiléa L., Silene Rothers, Paulo Boente, and Roberto Santos. "Primary Cutaneous Eosinophil-Rich Anaplastic Large Cell Lymphoma: Report of an Unusual Case and Literature Review." Journal of Cutaneous Medicine and Surgery 12, no. 2 (2008): 88–92. http://dx.doi.org/10.2310/7750.2007.00035.

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Background: Cutaneous, neutrophil-rich anaplastic large cell lymphoma (ALCL) is an uncommon variant of ALCL that may be confused with inflammatory dermatoses. Objective and methods: We describe an eosinophil-rich variant of ALCL occurring on the left ear without systemic involvement. The lesion had inflammatory characteristics, which led initially to a histological diagnosis of an inflammatory process. Two months later, a second biopsy diagnosed eosinophil-rich variant of ALCL. The patient underwent radiation therapy, but due to the extensive deformation and mutilation of the ear, the patient

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Supiyaphun, Pakpoom, Kornkiat Snidvongs, and Shanob Shuangshoti. "Salivary gland choristoma of the middle ear: case treated with KTP laser." Journal of Laryngology & Otology 114, no. 7 (2000): 528–32. http://dx.doi.org/10.1258/0022215001906066.

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Salivary gland choristoma of the middle ear is rare. It consists of non-malignant, non-growing, normal salivary gland tissue in the middle ear. It is a developmental abnormality that occurs around the proximal part of the second branchial arch before the fourth month of intrauterine life.The authors found the 25th recorded case in our centre and another 24 reported cases from a review of the literature between 1961 and 1999. Intratympanic salivary gland choristoma frequently occurs during the first and second decades of life and with a female preponderance (56 per cent). Nearly all the patient

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B. Cruz-Ordinario, Mel Valerie, Edgar Christian S. Cuaresma, Margarita D. Guevarra, Elsie L. Lim, and Marcelo Severino B. Imasa. "External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma." Asian Pacific Journal of Cancer Care 8, no. 1 (2023): 201–6. http://dx.doi.org/10.31557/apjcc.2023.8.1.201-206.

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Introduction: Squamous cell carcinoma of the temporal bone is extremely rare comprising 0.2% of all tumors of head and neck. Symptoms are nonspecific and may be mistaken for other more benign conditions as otitis, cholesteatoma and polyp. Hence, this condition may present as a diagnostic challenge. Case Discussion: We describe a case series of three patients who presented with external auditory canal (EAC) mass. The most common signs and symptoms are pruritus, decreased hearing and yellowish discharge. They were initially treated with otic antibiotics which afforded no relief. The first case i

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MacFadyen, D. J., R. J. Schneider, and I. A. Chisholm. "A Syndrome of Brain, Inner Ear and Retinal Microangiopathy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 14, no. 3 (1987): 315–18. http://dx.doi.org/10.1017/s0317167100026706.

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ABSTRACT:We report the seventh case of a self-limiting syndrome of brain, inner ear and retinal microangiopathy which affects adult women producing mild to moderate mental status and personality changes, mild pyramidal and cerebellar dysfunction, patchy and asymmetrical visual loss secondary to non-inflammatory retinal infarctions, and asymmetrical neurosensory hearing loss. There is no clinical or laboratory evidence of involvement beyond the brain, the eyes and the ears. Magnetic resonance imaging or brain biopsy in previously reported cases best outline the brain pathology: multiple microin

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