Kliknij ten link, aby zobaczyć inne rodzaje publikacji na ten temat: Egar.

Rozprawy doktorskie na temat „Egar”

Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych

Wybierz rodzaj źródła:

Sprawdź 50 najlepszych rozpraw doktorskich naukowych na temat „Egar”.

Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.

Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.

Przeglądaj rozprawy doktorskie z różnych dziedzin i twórz odpowiednie bibliografie.

1

Hernández, Roura Sergio Armando. "La recepción e influencia de Egar Allan Poe en México (1859-1922)." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/384938.

Pełny tekst źródła
Streszczenie:
Hasta hace muy poco la literatura fantástica había sido un género infravalorado en México, cuando no se dudaba de su existencia. La aparición de antologías dedicadas a esta producción, el rescate en los últimos años de la obra de escritores de indiscutible valor para el género, así como la rica y variada producción de obras literarias que se alejan de lo mimético ha jugado un papel importante en el cambio de perspectiva. Sin embargo, el empuje que encontramos en lo que respecta al siglo XX se ha visto frenado cuando se intenta vislumbrar los orígenes de este género debido a que el siglo XIX es
Style APA, Harvard, Vancouver, ISO itp.
2

Torreiro, Gómez Casimiro. "Continuidades y rupturas. Edgar Neville, entre república y primer franquismo (1931-1945)." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/368236.

Pełny tekst źródła
Streszczenie:
El objetivo de esta tesis es situar en qué situación se encontraba el cine español cuando, en 1939, se produjo el trascendental paso que daría lugar a una nueva insitucionalidad, nacida de una cruenta y larga guerra civil y que habría de durar hasta 1975. Qué factores caracterizaban a su industria, cuáles se mantuvieron tras el Rubicón de 1939, y cuáles cambiarían el cine español desde entonces. También, en qué medida, y a pesar de la existencia de una férrea censura de Estado, algunos filmes dejan ver, para una mirada contemporánea, la continuidad de viejas formas del espectáculo popular espa
Style APA, Harvard, Vancouver, ISO itp.
3

Fraguas, Garcia Susanna. "Regulació de la regeneració anterior a través de la via egfr-3/egr-4 en la planària Schmidtea mediterranea." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/277417.

Pełny tekst źródła
Streszczenie:
Les planàries d'aigua dolça s’han convertit en un bon model per estudiar la regeneració a nivell genètic i molecular, gràcies a la seva capacitat de reconstruir qualsevol fragment danyat a conseqüència d’una amputació, des de qualsevol eix corporal i formar un nou organisme adult en un termini de temps molt curt. Al mateix temps, durant l’estadi adult en l’absència d’una ferida, les planàries són capaces de reemplaçar les cèl•lules diferenciades dels teixits vells mitjançant una proliferació i diferenciació constant de les cèl•lules mare o neoblasts. Tenim al nostre abast un ampli coneixeme
Style APA, Harvard, Vancouver, ISO itp.
4

Sjöström, Sara. "Risk and prognostic factors for malignant glioma." Doctoral thesis, Umeå universitet, Onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-61905.

Pełny tekst źródła
Streszczenie:
Background: Glioblastoma is the most common and aggressive type of glioma and associated with poor prognosis. Apart from ionizing radiation and some rare genetic disorders, few aetiological factors have been identified for primary brain tumours. Inverse associations to asthma and low IgG levels for varicella zoster virus have in previous studies indicated that the immune system may play a role in glioma development. Little is known about prognostic factors in glioma. Previous studies have shown an association between age, Karnofsky performance status, O6-methylguanine-DNA methyltransferase (MG
Style APA, Harvard, Vancouver, ISO itp.
5

Kramer, Elizabeth L. "Role of the EGFR Pathway in Lung Remodeling and Disease." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250206890.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
6

Bauer, Philip [Verfasser]. "Der Einfluss der EGFR Expressionsdichte auf die EGFR Antikörper gerichteten Abwehrmechanismen / Philip Bauer." Kiel : Universitätsbibliothek Kiel, 2017. http://d-nb.info/1127044206/34.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
7

Hamilton, S. J. "An investigation of EGFR binding and modulation of EGFR signalling pathways using synthetic peptides." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403480.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
8

Balko, Justin M. "THE PHARMACOGENOMICS OF EGFR-DEPENDENT NSCLC: PREDICTING AND ENHANCING RESPONSE TO TARGETED EGFR THERAPY." Lexington, Ky. : [University of Kentucky Libraries], 2009. http://hdl.handle.net/10225/1062.

Pełny tekst źródła
Streszczenie:
Thesis (Ph. D.)--University of Kentucky, 2009.<br>Title from document title page (viewed on September 17, 2009). Document formatted into pages; contains: viii, 175 p : ill. (some col.). Includes abstract and vita. Includes bibliographical references (p. 103-123).
Style APA, Harvard, Vancouver, ISO itp.
9

Žďárská, Petra. "Vykazování finančního umístění společnosti EGAP." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-9177.

Pełny tekst źródła
Streszczenie:
Diploma thesis focuses on definition of investments both from economic (financial) and accounting point of view. It solves question of all institutional investors at financial market -- which assets to choose in order to have their investments placed in safe, profitable and liquid way. Besides question -- how to place the investments -- specific aspects of financial reporting under Czech accounting standards and International Financial Reporting Standards are discussed. Practical part analyzes actual financial investments of insurance companies operating at czech insurance market.
Style APA, Harvard, Vancouver, ISO itp.
10

Pýcha, Mikuláš. "Existence EGAP pohledem tržních a státních selhání (přínosy a náklady EGAP z pohledu České republiky)." Master's thesis, Vysoká škola ekonomická v Praze, 2017. http://www.nusl.cz/ntk/nusl-360167.

Pełny tekst źródła
Streszczenie:
Diploma thesis focuses on an issue regarding the state interventions into market economy and provides the explanation, how does different economic ideas approach this issue and whether they support or deny the state interventions. It focuses in detail on support that is provided towards exporting companies. Czech Republic has two export credit agencies, firstly Export Guarantee and Insurance Corporation (EGAP) and secondly Czech Export Bank (CEB). This diploma thesis analyses only EGAP´s structure and quantifies the impact of its existence on Czech economy. In a first part we analyze historica
Style APA, Harvard, Vancouver, ISO itp.
11

Liccardi, G. "Nuclear EGFR modulation of DNA repair." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335897/.

Pełny tekst źródła
Streszczenie:
Overexpression of the epidermal growth factor receptor (EGFR) is associated with resistance to chemotherapy and radiotherapy. EGFR involvement, in repair of radiation-induced DNA damage, is mediated by association with the catalytic subunit of DNA protein kinase (DNAPKcs). This study investigated the role of EGFR nuclear import, and its association with DNAPKcs, on DNA repair following treatment either with cisplatin or ionizing radiation (IR). EGFR- null murine NIH3T3 cells were transfected with wild type or with mutated EGFR (mutations found in human cancers L858R, EGFRvIII and mutations in
Style APA, Harvard, Vancouver, ISO itp.
12

Housden, B. "Notch targets and EGFR pathway regulation." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604264.

Pełny tekst źródła
Streszczenie:
Previous work in the lab identified potential Notch targets in a muscle related <i>Drosophila</i> cell line using a combination of genome wide expression array, chromatin immunoprecipitation (ChIP) and bioinformatics approaches. My project was focussed on investigating the regulation of EGFR pathway components by Notch signalling and unravelling mechanisms by which this crosstalk is dependent on context. Previous genetic studies have demonstrated extensive crosstalk between the Notch and EGFR pathways. The unexpected result from the genome wide studies was the overrepresentative of EGFR pathwa
Style APA, Harvard, Vancouver, ISO itp.
13

Lee, Richard William. "MET-EGFR dimerisation in lung adenocarcinoma is dependent on EGFR mutations and altered by MET kinase inhibition." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/metegfr-dimerisation-in-lung-adenocarcinoma-is-dependent-on-egfr-mutations-and-altered-by-met-kinase-inhibition(3a738a35-f82d-4eb6-83a3-150160d12045).html.

Pełny tekst źródła
Streszczenie:
Prognosis in advanced stage lung cancer is extremely poor with few effective therapies. EGFR tyrosine kinase inhibitors (TKIs) have high response rates in patients with activating EGFR mutations and are now an established part of therapy in selected patients. Such advances herald a previously unprecedented enthusiasm for the possibilities of targeted therapy. Acquired resistance however is widespread - the EGFR T790M mutation in particular represents approximately 50% of these. MET amplification is also an important route of resistance and preclinical data suggests synergy between therapies ta
Style APA, Harvard, Vancouver, ISO itp.
14

Reifarth, Simon. "Efficiency and Mixing Analysis of EGR-Systems for Diesel Engines." Doctoral thesis, KTH, Förbränningsmotorteknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-140850.

Pełny tekst źródła
Streszczenie:
The reduction of fuel consumption and the reduction of toxic emissions are the main goals of research and development in the area of internal combustion engines. The use of exhaust gas recirculation (EGR) to come further in that direction is today an established method for diesel engines. EGR reduces the emissions of nitrogen oxides with a low penalty in fuel consumption. The increasingly hard regulations on emissions put high pressure on the manufacturers to improve these systems. The present work aims at increasing the knowledge in the area of EGR. Two of the main challenges when applying EG
Style APA, Harvard, Vancouver, ISO itp.
15

Andersson, Lena. "Singeltubvärmeväxlare för EGR-applikationer." Thesis, KTH, Energiteknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-170914.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
16

Pritchett, Kathleen S. "The Career and Legacy of Hornist Joseph Eger: His Solo Career, Recordings, and Arrangements." Thesis, connect to online resource, 2008. http://digital.library.unt.edu/permalink/meta-dc-6060.

Pełny tekst źródła
Streszczenie:
Thesis (D.M.A.)--University of North Texas, 2008.<br>System requirements: Adobe Acrobat Reader. Accompanied by 4 recitals, recorded Nov. 26, 2001, Nov. 18, 2002, Apr. 7, 2003, and Feb. 25, 2008. Includes bibliographical references (p. 40-43).
Style APA, Harvard, Vancouver, ISO itp.
17

Snowdon, David. "Pierce Egan, and pugilistic writing 1812-45." Thesis, University of Newcastle Upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445573.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
18

Vanlandingham, Phillip Allen. "Rab7 regulation of EGFR trafficking and signaling." Oklahoma City : [s.n.], 2009.

Znajdź pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
19

Liffers, Katrin [Verfasser], and Katrin [Akademischer Betreuer] Lamszus. "Identifikation von Resistenzmechanismen gegenüber EGFR-Tyrosinkinase Inhibitoren in EGFR-amplifizierten und EGFRvIII-positiven Glioblastomen / Katrin Liffers. Betreuer: Katrin Lamszus." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2015. http://d-nb.info/107464249X/34.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
20

Wallentin, Mathias. "Undersökning av EGR-system i singelcylinder-provcell – med fokus på ökad tillgänglig EGR-mängd." Thesis, Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-67840.

Pełny tekst źródła
Streszczenie:
Dagens förbränningsmotorer ställs inför allt högre krav på att minimera de miljöfarliga restprodukter som förbränningen av luft och bränsle ger upphov till. Efterbehandlingssystem har utvecklats i olika former för detta ändamål, där en utav dessa är EGR: Exhaust gas recirculation som bygger på att en del av motorns avgaser överförs tillbaka in i motorn och minskar bildningen av termiska kvävoxider. I detta examensarbete undersöktes ett EGR-system i AVL:s singelcylinder-provcell, där målsättningen var att kartlägga komponenternas inverkan på EGRflödet samt undersöka EGR-systemets begränsningar
Style APA, Harvard, Vancouver, ISO itp.
21

Bu, Yubai. "New synthetic routes to nitrogen heterocycles : natural products and novel drug scaffolds." Thesis, Loughborough University, 2017. https://dspace.lboro.ac.uk/2134/27482.

Pełny tekst źródła
Streszczenie:
This thesis is divided into three main sections. The first chapter contains a brief review of nitrogen heterocyclic chemistry. The second chapter reports the results and their discussion of new heterocyclic chemistry, and the experimental details are provided in the fourth chapter.
Style APA, Harvard, Vancouver, ISO itp.
22

Menezes, Sharleen Valerie. "Understanding the molecular mechanisms that underlie the anti-cancer activity of the metastasis suppressor, NDRG1 in the treatment of cancer." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20193.

Pełny tekst źródła
Streszczenie:
Pancreatic cancer is an aggressive disease that continues to be associated with low survival rates, therefore there is a need for more targeted therapies. This thesis sought to elucidate the mechanism of action of a well-known metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1). In addition, this thesis proposed a promising therapeutic strategy, exploring the use of a potent new class of di-2-pyridylketone thiosemicarbazone anti-cancer agents that up-regulate NDRG1. NDRG1 can suppress the epithelial mesenchymal transition, a key step in metastasis. We demonstrated that NDRG1 inhi
Style APA, Harvard, Vancouver, ISO itp.
23

Kvarnbrink, Samuel. "The importance og LRIG1 in lung cancer." Thesis, Umeå universitet, Onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57834.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
24

Roetzer, Silvia. "Fraktionierte lokoregionale Radioimmuntherapie mit 213Bi-anti-EGFR-MAk." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-160591.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
25

Pfäffle, Heike. "Defective DNA repair in EGFR-mutant lung cancer." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-162407.

Pełny tekst źródła
Streszczenie:
In patients with lung cancer whose tumors harbor activating mutations in the EGF receptor (EGFR), increased responses to platinum-based chemotherapies are seen compared with wild-type cancers. However, the mechanisms underlying this association have remained elusive. Here, we describe a cellular phenotype of crosslinker sensitivity in a subset of EGFR-mutant lung cancer cell lines that is reminiscent of the defects seen in cells impaired in the Fanconi anemia pathway, including a pronounced G2–M cell-cycle arrest and chromosomal radial formation. We identified a defect downstream of FANCD2 at
Style APA, Harvard, Vancouver, ISO itp.
26

Willems, Sofie Henriëtte. "ADAMs as EGFR ligand sheddases in prostate cancer." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609342.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
27

Alves, Alice Manuela Santos. ""EGFR, e Lesões Displásticas do Colo do Útero"." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/57198.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
28

White, Audrey Lucille, and Audrey Lucille White. "Signaling Crosstalks: EGFR and TAZ in Breast Cancer." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/625241.

Pełny tekst źródła
Streszczenie:
Breast cancer is driven by multiple molecular aberrations, transforming benign epithelial cells into metastatic cancer. Identification of key signaling nodes underlying metastasis and resistance to treatment is crucial to improving targeted therapies. This review examines two oncogenes driving epithelial to mesenchymal transition (EMT) and the acquisition of cancer stem cell properties. The epidermal growth factor receptor (EGFR), a well-established oncogene driving migration, survival, and proliferation, activates several downstream signaling cascades including the AKT and MAPK pathway
Style APA, Harvard, Vancouver, ISO itp.
29

Lee, Tang-Cheng Threadgill David W. "Functional analysis of EGFR using a conditional allele." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1730.

Pełny tekst źródła
Streszczenie:
Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum of Genetics & Molecular Biology." Discipline: Genetics and Molecular Biology; Department/School: Medicine.
Style APA, Harvard, Vancouver, ISO itp.
30

Alves, Alice Manuela Santos. ""EGFR, e Lesões Displásticas do Colo do Útero"." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/57198.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
31

GIORDANO, FEDERICA. "Investigating the role of p65BTK as an emerging therapeutic target in NSCLC." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2019. http://hdl.handle.net/10281/241339.

Pełny tekst źródła
Streszczenie:
Il tumore al polmone è la principale causa di morte per tumore al mondo sia negli uomini che nelle donne. Il tumore polmonare non a piccole cellule (NSCLC) è il più frequente ed è relativamente insensibile a chemioterapia e radioterapia. Nonostante lo sviluppo di terapie molecolari personalizzate contro specifiche “mutazioni driver” e la combinazione di chemioterapia e terapie a bersaglio molecolare, la mortalità per tumore al polmone rimane molto alta a causa dello sviluppo di resistenza alle diverse terapie. Pertanto, rimane particolarmente urgente ricercare nuove terapie per NSCLC. Recentem
Style APA, Harvard, Vancouver, ISO itp.
32

Reifarth, Simon. "EGR-Systems for Diesel Engines." Licentiate thesis, KTH, Machine Design (Div.), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12205.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
33

Ståhl, Daniel, and Freddie Tydal. "Direct-EGR tillämpat på HCCI." Thesis, KTH, Maskinkonstruktion (Inst.), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-101174.

Pełny tekst źródła
Streszczenie:
The Homogeneous Charge Compression Ignition (HCCI) engine is promising in terms of low NO x, low particulates and high efficiency. Due to its homogeneous charge, where the combustion starts almost simultaneously from a number of points in the combustion chamber, only lean mixtures are possible to burn because of the resulting rapid combustion, which is much faster than the combustion in an SI-engine or a diesel engine. When richer mixtures are used the combustion will start earlier and also be more violent. To phase the combustion later and lower the combustion speed, external cooled EGR can b
Style APA, Harvard, Vancouver, ISO itp.
34

Al-Akhrass, Hussein. "Un rôle inédit de la sortiline dans le contrôle du transport rétrograde de l'EGFR pour limiter la croissance tumorale." Thesis, Limoges, 2017. http://www.theses.fr/2017LIMO0035/document.

Pełny tekst źródła
Streszczenie:
Le cancer du poumon est le troisième cancer le plus fréquent chez les femmes et le deuxième chez les hommes, il est la cause principale de décès par cancer dans le monde, avec une mortalité annuelle supérieure à 1 million. Malgré des progrès remarquables dans la thérapie ciblée, la majorité des patients atteints de cancer du poumon sont diagnostiqués dans un stade avancé où ils ne connaissent pas d'amélioration significative de leur survie globale. Les récepteurs à domaine tyrosine kinase, tels que le récepteur du facteur de croissance épidermique (EGFR), traduisent les informations du microen
Style APA, Harvard, Vancouver, ISO itp.
35

Das, Gupta Paromita Clinical School Prince of Wales Hospital Faculty of Medicine UNSW. "Gene profiling in soft tissue sarcoma: predictive value of EGFR in sarcoma tumour progression and survival." Publisher:University of New South Wales. Clinical School - Prince of Wales Hospital, 2007. http://handle.unsw.edu.au/1959.4/43259.

Pełny tekst źródła
Streszczenie:
Despite improvements in the clinical management of soft tissue sarcomas (STS), 50% of patients will die of metastatic disease that is largely unresponsive to conventional chemotherapeutic agents. The aims of this study were to identify genes and pathways that are dysregulated in progressive and metastatic STS. In addition to this, cell lines from fresh tumours were initiated and established, thus increasing the repository of cell lines available for functional studies. Recent advances in the understanding of the molecular biology of STS have thus far not resulted in the use of molecular marker
Style APA, Harvard, Vancouver, ISO itp.
36

Su, Hsin-Yuan. "Therapeutic Potential of EGFR Derived Peptides in Breast Cancer." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/293486.

Pełny tekst źródła
Streszczenie:
The epidermal growth factor receptor (EGFR) belongs to the erbB family of receptor tyrosine kinases which consists of four members (EGFR, ErbB2, ErbB3 and ErbB4). Upon ligand binding, the EGFR is capable of dimerization with other erbB receptors and propagates signals regulating a diverse array of cellular physiologies, including cell growth, migration and survival. Dysregulation of the EGFR is important for development and progression of different types of cancers, including breast cancer. Breast cancer is the second leading cause of cancer death in women. EGFR overexpression has been observ
Style APA, Harvard, Vancouver, ISO itp.
37

Dayde, Delphine. "Liens fonctionnels entre l'EGFR et P14ARF : contribution à la carcinogenèse pulmonaire." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENV071/document.

Pełny tekst źródła
Streszczenie:
L'EGFR est un récepteur transmembranaire à activité tyrosine kinase (TK) qui transduit des signaux de prolifération et de survie cellulaire. Dans les cancers du poumon, son activité est fréquemment dérégulée par surexpression et/ou par mutation au niveau de son domaine TK. Ces mutations sont principalement de deux types (EGFR-L858R et EGFR-Del19) et sont dites activatrices car elles induisent une activation constitutive des signalisations oncogéniques de l'EGFR. Elles sont aussi un facteur prédictif de réponse aux EGFR-TKIs qui inhibent spécifiquement ce récepteur. P14ARF est un suppresseur de
Style APA, Harvard, Vancouver, ISO itp.
38

Raimbourg, Judith. "Effets du cisplatine sur la sensibilité des cancers bronchiques non à petites cellules EGFR sauvage aux inhibiteurs de tyrosine kinase anti EGFR." Thesis, Nantes, 2018. http://www.theses.fr/2018NANT1028/document.

Pełny tekst źródła
Streszczenie:
Les inhibiteurs de tyrosine kinase (ITK) anti EGFR ont très nettement amélioré la survie des patients atteints de cancers bronchiques non à petites cellules (CBNPC) métastatiques porteurs d’une mutation activatrice d’EGFR. En l’absence de mutation activatrice, le bénéfice de ces traitements est marginal et semble conditionné par l’utilisation préalable de la chimiothérapie. Dans cette étude, l’exposition préalable de cellules de CBNPC EGFR sauvage à des doses sub-léthales de cisplatine induit une augmentation de la phosphorylation d’EGFR augmentant la sensibilité de ces cellules à l’erlotinib,
Style APA, Harvard, Vancouver, ISO itp.
39

Ganzetti, Giulia. "Tossicità cutanea da inibitori dell’Epidermal Growth Factor Receptor (EGFR): valutazione clinico-istologica ed approccio terapeutico." Doctoral thesis, Università Politecnica delle Marche, 2014. http://hdl.handle.net/11566/242853.

Pełny tekst źródła
Streszczenie:
L'inibizione del recettore del fattore di crescita epidermico (EGFR) rappresenta un importante traguardo raggiunto nella ricerca e nello sviluppo della terapia dei tumori solidi epiteliali. Si tratta di una classe di farmaci biologici che trovano attualmente ampio utilizzo nel trattamento di tumori del colon-retto, del pancreas, del polmone (NSCLC), della testa-collo e della mammella, metastatici e non responsivi alle chemioterapie convenzionali. L'EGFR, oltre ad essere sovraespresso in numerose neoplasie epiteliali, è costituzionalmente presente nei cheratinociti dello strato basale del
Style APA, Harvard, Vancouver, ISO itp.
40

Albuschat, Rica. "Neue EGFR-Tyrosinkinase-Inhibitoren mit Salicyloyl- oder Chinazolin-Teilstrukturen." [S.l.] : [s.n.], 2003. http://www.diss.fu-berlin.de/2003/189/index.html.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
41

Dippel, Carsten. "Die Kompetenzabgrenzung in der Rechtsprechung von EGMR und EuGH." Doctoral thesis, [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=97305056X.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
42

Schäfer, Beatrix. "Transactivation of the EGFR Signal in Human Cancer Cells." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-23041.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
43

Brown, K. E. "EGFR signalling and ommatidial orientation in the Drosophila eye." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596973.

Pełny tekst źródła
Streszczenie:
I have investigated the role of Epidermal Growth Factor Receptor (EGFR) signalling in the control of ommatidial orientation. Both over- and under-activation of the pathway lead to significant defects in ommatidial orientation, while leaving the polarity of ommatidial unaffected. This previously unrecognised function of EGFR signalling further adds to the multiple functions of the pathway in <i>Drosophila</i> eye development. I have shown that the initial rotational event proceeds normally in EGFR pathway mutants, but that orientation becomes disrupted later in development, leading to the sever
Style APA, Harvard, Vancouver, ISO itp.
44

Klinghammer, Konrad [Verfasser]. "Primäre und sekundäre Resistenzmechanismen der EGFR Blockade / Konrad Klinghammer." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1200409442/34.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
45

Mao, Yanlan. "Adhesion molecules in Drosophila EGFR signalling and retinal development." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612274.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
46

Albukhari, Ashwag. "Targeting EGFR signalling pathway in triple negative breast cancer." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:85d4bb10-385e-4187-8576-cf04f15f2871.

Pełny tekst źródła
Streszczenie:
Epidermal growth factor receptor (EGFR) is frequently overexpressed in the majority of triple negative breast cancer patients (TNBC). However, the molecular determinants behind their limited response to EGFR-targeted therapies are poorly understood. Here, both the acute and chronic responses of TNBC to the EGFR-targeted therapy, cetuximab (CTX), have been investigated. The expression of EGFR has been analyzed in a cohort of 2000 breast cancer tumours from the public dataset as well as in a panel of breast cancer cell lines. Furthermore, the response of TNBC cell lines to CTX has been investiga
Style APA, Harvard, Vancouver, ISO itp.
47

Mariuzzo, Junior Osvaldo. "Retrato e auto-retrato na obra de Egas Francisco." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/284929.

Pełny tekst źródła
Streszczenie:
Orientador: Maria de Fátima Morethy Couto<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Artes<br>Made available in DSpace on 2018-08-17T08:02:11Z (GMT). No. of bitstreams: 1 MariuzzoJunior_Osvaldo_M.pdf: 32441693 bytes, checksum: b23ed459f366d99a2b24d80e27dc321c (MD5) Previous issue date: 2010<br>Resumo: Egas Francisco pinta telas há mais de cinqüenta anos, sustentou-se durante todos esses anos com o dinheiro que recebe pela venda de suas obras e pelo ensino de artes, que por vezes o ajudou a sobreviver. Não é objetivo desse trabalho encaixar todas as peças do e
Style APA, Harvard, Vancouver, ISO itp.
48

Strieder, Luciana Rocha [UNESP]. "Análise da proteína EGFR em carcinoma espinocelular de lábio." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/132902.

Pełny tekst źródła
Streszczenie:
Submitted by LUCIANA ROCHA STRIEDER null (lucianastrieder@hotmail.com) on 2016-01-19T21:12:07Z No. of bitstreams: 2 dissertação 19.01.16 .pdf: 19074519 bytes, checksum: 646181ed6e1659fe081a91e6503d357f (MD5) dissertação 19.01.16 .pdf: 19074519 bytes, checksum: 646181ed6e1659fe081a91e6503d357f (MD5)<br>Approved for entry into archive by Sandra Manzano de Almeida (smanzano@marilia.unesp.br) on 2016-01-20T12:44:41Z (GMT) No. of bitstreams: 1 strieder_lr_me_sjc.pdf: 19074519 bytes, checksum: 646181ed6e1659fe081a91e6503d357f (MD5)<br>Made available in DSpace on 2016-01-20T12:44:41Z (GMT). N
Style APA, Harvard, Vancouver, ISO itp.
49

Pretto, Guilherme Gonçalves. "EGFR na sequência DRGE, BARRETT e adenocarcinoma de esôfago." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/39671.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
50

Sharif, Ariane. "Contrôle du phénotype astrocytaire par le couple TGFα-EGFR". Paris 6, 2005. http://www.theses.fr/2005PA066636.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
Oferujemy zniżki na wszystkie plany premium dla autorów, których prace zostały uwzględnione w tematycznych zestawieniach literatury. Skontaktuj się z nami, aby uzyskać unikalny kod promocyjny!