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Rozprawy doktorskie na temat „Escherichia coli”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Schnepel, Jörn. "Klonierung, Expression und Charakterisierung kryptischer Fibronektin-Proteinasen." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=969330472.

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2

Rang, Camilla. "Molecular and physiological characteristics of Escherichia coli growth in vitro and in the gastrointestinal tract of mice." Göteborg : [Dept. of General and Marine Microbiology, Göteborg University], 1997. http://catalog.hathitrust.org/api/volumes/oclc/38988157.html.

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3

Rosko, Jerko. "Osmotaxis in Escherichia coli." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28947.

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Bacterial motility, and in particular repulsion or attraction towards specific chemicals, has been a subject of investigation for over 100 years, resulting in detailed understanding of bacterial chemotaxis and the corresponding sensory network in many bacterial species including Escherichia coli. E. Coli swims by rotating a bundle of flagellar filaments, each powered by an individual rotary motor located in the cell membrane. When all motors rotate counter-clockwise (CCW), a stable bundle forms and propels the cell forward. When one or more motors switch to clock-wise (CW) rotation, their resp

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4

Rosser, Tracy. "Pathogenic potential of Escherichia coli O26 and sorbitol-fermenting Escherichia coli O157:NM." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4427.

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Verocytotoxin-producing Escherichia coli (VTEC) are important human pathogens that may cause diarrhoea, haemorrhagic colitis and haemolytic uremic syndrome (HUS). Worldwide, non-sorbitol-fermenting (NSF) VTEC O157:H7 is the most common serogroup associated with HUS but several non-O157:H7 serogroups have emerged as causes of this disease. This research investigated the pathogenic potential of two non-O157:H7 serogroups: O26 and sorbitol-fermenting (SF) O157:NM. While VTEC O26 have emerged as a significant cause of HUS in continental Europe, human infections associated with this pathogen are un

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5

Solecki, Olivia. "Explaining the urban and rural differences of Escherichia coli 0157 human infection in Grampian." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25203.

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6

Wu, Gilbert Kar Po. "Signal transduction responses to enteropathogenic Escherichia coli and Shiga toxin-producing Escherichia coli infections." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0007/MQ46054.pdf.

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7

Hesterberg, Micaela. "Charakterisierung einer unbekannten Redoxgruppe sowie der Konformation der NADH:Ubichinon-Oxidoreduktase (Komplex I) aus Escherichia coli." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964821672.

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8

Grabowski, Gabriele. "Untersuchungen zum Mechanismus der Katalyse und zu In-vivo-Selektionssystemen für die Anreicherung von Mutanten der Restriktionsendonuklease EcoRI mit veränderter DNA-Bindungs- oder Spaltspezifität." [S.l. : s.n.], 1998. http://deposit.ddb.de/cgi-bin/dokserv?idn=954823028.

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9

Uhland, Kerstin. "Biochemische und genetische Charakterisierung der Trehalasen TreA und TreF von Escherichia coli." [S.l. : s.n.], 1997. http://deposit.ddb.de/cgi-bin/dokserv?idn=958497885.

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10

Franke, Sylvia. "Das Kupfer-transportierende CusCFBA-Efflux-System aus Escherichia coli." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=967128110.

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11

Schneider, Frank. "Beta-Alaninaufnahme und Pantothensäureexkretion durch Escherichia coli." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968826105.

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12

Schauer, Stefan. "Die Glutamyl-tRNA-Reduktase aus Escherichia coli rekombinante Produktion, Enzymmechanismus und biochemische Charakterisierung /." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=97070304X.

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13

Niu, Lili. "Escherichia coli proteomics and bioinformatics." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1240.

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14

Kelemen, Peter. "Quantitativer Nachweis chlorungsvorgeschädigter Escherichia coli." Frankfurt a.M, 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964197170.

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15

Zundel, Michael. "Ribosome Degradation in Escherichia coli." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/152.

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Upon termination of translation, the fate of ribosomes is determined largely by the rate at which cells are growing. During periods of exponential growth, ribosomes are rapidly recycled, translation is re-initiated, and the ribosomes are extremely stable. However, when nutrient sources become limiting, and ribosomes are not actively translating, they may become substrates for degradation. While this phenomenon is well known, details of how the process is initiated and what are the signals for degradation have, until now, remained elusive. Here, I present in vitro and in vivo data showing

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16

Champion, Matthew Maurice. "Functional proteomics in Escherichia coli." Texas A&M University, 2005. http://hdl.handle.net/1969.1/3194.

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Cells respond to their environment with programmed changes in gene expression. Cataloging these changes at the protein level is key towards understanding the physiology of an organism. Multi-subunit and multi-protein complexes are also important and pathogenic and physiologic processes. In order to identify expressed proteins and potential protein complexes, we utilized a combination of non-denaturing chromatography and peptide mass fingerprinting. This approach allows us to identify the components of protein mixtures, as well as information lost in traditional proteomics, such as subunit asso

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17

Skoog, Karl. "Cell division in Escherichia coli." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-62908.

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The Gram-negative bacterium Escherichia coli is a model system to describe the biochemistry and cell biology of cell division in bacteria. This process can be divided into three major steps. The first step involves the replication of the DNA, followed by an elongation step in which the cells become twice as long. In the last step the elongated cell constricts in the middle and the two daughter cells are separated. The cell division process in E. coli has been extensively studied for at least 50 years and a lot is known, however many details are still vague. New proteins involved in the process

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18

Robertson, Fiona E. "Starvation-survival in Escherichia coli." Thesis, University of Warwick, 1996. http://wrap.warwick.ac.uk/63636/.

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The population dynamics of carbon-starved E. coli K12 cultures was investigated. It was found that less cell lysis occurred when cells were previously grown in low glucose concentrations. Exponential-phase cells grown previously in 0.05% (w/v) glucose had survival rates comparable with their stationary-phase counterparts, suggesting that the rate of growth is more important in determining the outcome of starvation than the phase of batch culture growth. Long-termstarved cells (18-24 months) showed very little protein, DNA and RNA synthesis. Methionine was shown to alter the de novo synthesis p

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19

Burton, Claire Louise. "Norepinephrine, iron and Escherichia coli." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342475.

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20

Kershaw, Christopher John. "Copper homeostasis in Escherichia coli." Thesis, University of Birmingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419690.

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21

Storey, A. "Exonuclease V of Escherichia coli." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374741.

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22

Burke, Denis Anthony. "Ulcerative colitis and Escherichia coli." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309075.

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23

McClellan, J. A. "Studies on Escherichia coli-mutabile." Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355195.

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24

Esteves, de Matos Ferrer Raquel Sofia NegraÌƒo Sequeira. "Metabolic quiescence in Escherichia coli." Thesis, University of Warwick, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397740.

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25

MacLean, Morag. "Methylglyoxal detoxification in Escherichia coli." Thesis, University of Aberdeen, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287604.

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Methylglyoxal is a naturally occurring toxic electrophile which, in<I> E. coli</I>, can be detoxified by several routes. This study has focused on the glutathione-dependent glyoxalase system. The genes encoding glyoxalase I (<I>gloA</I>) and glyoxalase II (<I>gloB</I>) were identified in the <I>E. coli</I> genome and cloned into the multi-copy plasmid pHG165. A null mutant in glyoxalase I (Δ<I>glo</I>A::KanR) was also created. Cells overexpressing glyoxalase I exhibit elevated rates of detoxification and enhanced tolerance of methylglyoxal. Analysis of the Δ<I>gloA</I> mutant has revealed that

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26

Rembacken, Björn Joakim. "Escherichia coli and ulcerative colitis." Thesis, University of Leicester, 2003. http://hdl.handle.net/2381/29440.

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27

Blake, Catherine E. "Illegitimate recombination in Escherichia coli." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/15058.

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The factors affecting deletion of long DNA palindromes from high copy number cloning vectors are investigated with particular reference to the mode of deletion and it is shown that the deletion of a 571 bp palindrome deleted from pMS7 using 3 bp repeats. A shorter 109 bp palindrome deleted from a related plasmid using 7 bp direct repeats and the mode of deletion is unaffected by the genotype of the host strain. There also appears to be a bias for the deletion of palindromic sequences on the lagging strand of a replication fork. It is also shown that in a wild-type <I>E. coli</I> strain there i

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28

Davis, Elaine Olive. "Xylose transport in Escherichia coli." Thesis, University of Cambridge, 1986. https://www.repository.cam.ac.uk/handle/1810/270399.

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29

Saragosti, Jonathan. "Chimiotactisme collectif de Escherichia coli." Paris 6, 2010. http://www.theses.fr/2010PA066329.

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La bactérie Escherichia coli nage dans les liquides au moyen de ses flagelles en suivant une trajectoire qui est une marche aléatoire ˆ trois dimensions. Celle-ci est biaisée en réponse ˆ des gradients chimiques. Ce microorganisme chimiotactique peut ainsi s'orienter vers les sources de nourriture et établir une communication avec ses congénères lorsqu'il sécrète des molécules attractives. Dans des géométries confinées, où les gradients chimiques peuvent persister, les bactéries s'attirent ainsi mutuellement alors que la population dans son ensemble migre la recherche de nutriments. On observe

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30

Broadhead, Richard Ian. "Metabolic flexibility in Escherichia coli." Thesis, University of Aberdeen, 1998. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU104201.

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This study of the relationship between heterologous protein production and bacterial growth has shown that foreign protein can account for as much as 30% of the total cell protein without the specific growth rate being affected. Higher levels of foreign protein production are achieved at lower growth rates. Foreign protein is synthesised without any increase in ribosome number or ribosome activity occurring in the recombinant cells relative to their parent strain, i.e. the capacity of parental and recombinant cells to synthesise protein is the same. These observations are explained in terms of

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31

Slade, Kristin M. Pielak Gary J. "Protein diffusion in Escherichia coli." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2508.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Oct. 5, 2009). " ... in partial fulfillment of the requirements for the degree of Doctorate of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.

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32

Fox, Sian L. "Verocytotoxin expression in Escherichia coli." Thesis, University of Warwick, 1992. http://wrap.warwick.ac.uk/110785/.

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In order to examine the physiology of verotoxin (VT) production in vitro, it was necessary to develop an assay to enable specific measurement of VTl and VT2 expression. Initial efforts focussed on quantifying VTl and VT2 messenger RNA synthesis. RNA extraction and electrophoresis was consistently achieved, however, subsequent probing of Northern filters was not successful. A gene fusion between the slt-ll operon and the transposon vector TnphoA, such that expression of the phoA gene was brought under the control of the 5/MI promoter, was then developed. The presence and site of insertion of Tn

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33

McAuliffe, Laura. "Stress responses of Escherichia coli." Thesis, University of Bath, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248098.

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34

Harding, Amanda. "Mechanisms of acid protection mediated by periplasmic chaperones in Escherichia coli." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25744.

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35

Ozyamak, Ertan. "The analysis of methylglyoxal detoxification and stress responses in Escherichia coli." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources. Restricted: no access until Nov. 20, 2011, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=59008.

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36

Silva, Mídana Felismino da. "Escherichia coli e a resistência antibiótica: uma análise do padrão de evolução da resistência da Escherichia coli aos antibióticos no distrito de Castelo Branco, de 2006 a 2008." Master's thesis, Universidade da Beira Interior, 2009. http://hdl.handle.net/10400.6/1048.

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O aumento inabalável da resistência da E. coli aos antibióticos e as diferenças geográficas na sua prevalência levam com que seja imprescindíveis os estudos locais de prevalências e das tendências evolutivas das resistências. Objectivo: Analisar a prevalência e as tendências evolutivas da resistência da E. coli no distrito de Castelo Branco de Janeiro de 2006 a Dezembro de 2008 Método: Trata-se de um estudo descritivo com uma abordagem quantitativa. Foram analisadas todos os resultados dos testes de sensibilidade aos antibióticos efectuados nos laboratórios de microbiologia do Centro Hospitala

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37

Nemec, Michelle D. Drummond Massengale Andrea Rene. "Analysis of Escherichia coli populations in a large watershed." Waco, Tex. : Baylor University, 2008. http://hdl.handle.net/2104/5174.

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38

Hook-Barnard, India G. "Molecular analysis of regulatory elements within the escherichia coli fepB leader mRNA." free to MU Campus, others may purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091932.

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39

Robelek, Rudolf. "Untersuchungen zur Transkriptionsantitermination in Escherichia coli." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965257223.

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40

Landgraf, Frank Thomas. "Expression von Holophytochrom in Escherichia coli." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968412157.

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41

Dadgar, Ashraf. "Detection of enterohemorrhagic Escherichia coli (EHEC)." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6011.

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<p>Escherichia coli is a natural inhabitant of the intestines of both humans and animals, but there are also several pathogenic types of E. coli which cause disease in humans.</p><p>Strains of enterohemorrhagic E. coli (EHEC) have been associated with outbreaks of diarrhea, hemorrhagic colitis and hemolytic uremic syndrome in humans. Most clinical signs of disease arise as a consequence of the production of shigatoxin 1 and 2 or combination of these toxins. Other major virulence factors include EHEC hemolysin and intimin, the product of the eae gene that is involved in attaching and effacing a

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42

Ibwala, Nsatam-Yamumi. "Escherichia coli :hémagglutination, hémolyse et adhésion." Doctoral thesis, Universite Libre de Bruxelles, 1989. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213209.

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43

Martin, Mathew Paul. "Mechanistic studies of Escherichia coli transketolase." Thesis, University of Exeter, 2008. http://hdl.handle.net/10036/88813.

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The enzyme transketolase is found in nature as part of the Pentose Phosphate Pathway to rearrange large sugar phosphates. It also is an important enzyme for carboncarbon bond formation for industrial biocatalysis. The work presented in this thesis describes the purification, crystallisation, characterisation and structural determination of the recombinant Escherichia coli transketolase complexed with the substrate hydroxypyruvate and potential inhibitor fluoropyruvate. The native transketolase and the transketolase-hydroxypyruvate structures were solved to a 1.18 and 1.05 Å resolution respecti

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44

Baptist, Guillaume. "Réseaux de régulation chez Escherichia coli." Phd thesis, Université de Grenoble, 2012. http://tel.archives-ouvertes.fr/tel-00772446.

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L'adaptation d'une bactérie aux changements de son environnement est contrôlée par un réseau de régulation large et complexe, faisant intervenir de nombreux acteurs et modules différents. Dans ce travail, nous avons étudiés un module de régulation spécifique, contrôlant l'adaptation de la bactérie Escherichia coli à un changement de sources de carbone. Dans un milieu contenant du glucose et de l'acétate, la croissance est divisée en deux phases : les bactéries utilisent préférentiellement le glucose et commencent à métaboliser l'acétate qu'après l'épuisement du glucose. En effet, la présence d

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45

Baaghil, Suzanne. "Mechanistic studies of Escherichia coli bacterioferritin." Thesis, University of East Anglia, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398799.

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46

Moore, Tim. "The RdgC protein of Escherichia coli." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250574.

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47

Ince, J. E. "Formation of ethylene by Escherichia coli." Thesis, University of Kent, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355189.

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48

McHugh, Jonathan. "The fur modulon of Escherichia coli." Thesis, University of Reading, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288684.

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49

Timms, Andrew Robert. "Spontaneous mutagenesis in stressed Escherichia coli." Thesis, Open University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244410.

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50

Orchard, Lisa Marguerite Denise. "The 1-phosphofructokinase of Escherichia coli." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259621.

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