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1

Okeleye, Benjamin Ifeoluwa. "Studies on the antimicrobial, antioxidant and antiproliferative potential of the ethyl acetate extract and compounds of Peltophorum africanum." Thesis, University of Fort Hare, 2014. http://hdl.handle.net/10353/d1016165.

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Cells are constantly exposed to a variety of oxidizing agents, some of which are necessary for life. Oxidants produced in excess can cause an imbalance, leading to oxidative stress, especially in chronic bacterial, viral, and parasitic infections. This can result to damage of biomolecules such as lipids, proteins, and DNA, hence, an increased risk for cancer. Plants have a long history of use in the treatment of cancer. Plant secondary metabolites have proved to be an excellent reservoir of new medical compounds. Fruits, vegetables, and whole grains contain a wide variety of antioxidant phytoc
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Aragão, Danielle Maria de Oliveira. "Cecropia pachystachya Trécul como adjuvante no tratamento do diabetes melito." Universidade Federal de Juiz de Fora (UFJF), 2015. https://repositorio.ufjf.br/jspui/handle/ufjf/4276.

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Submitted by isabela.moljf@hotmail.com (isabela.moljf@hotmail.com) on 2017-04-27T15:30:59Z No. of bitstreams: 1 daniellemariadeoliveiraaragao.pdf: 4293901 bytes, checksum: 9fe0e48b323213abc9a30b33ba1f90db (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-05-12T15:50:14Z (GMT) No. of bitstreams: 1 daniellemariadeoliveiraaragao.pdf: 4293901 bytes, checksum: 9fe0e48b323213abc9a30b33ba1f90db (MD5)<br>Made available in DSpace on 2017-05-12T15:50:14Z (GMT). No. of bitstreams: 1 daniellemariadeoliveiraaragao.pdf: 4293901 bytes, checksum: 9fe0e48b3
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Makhaba, Masixole. "Phytochemical studies of extracts from Aloe succotrina." University of the Western Cape, 2017. http://hdl.handle.net/11394/6457.

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Magister Scientiae - MSc (Chemistry)<br>Global climate change and geographical differences are two major parameters known to have, either, direct or indirect influence on the production of secondary metabolites in plants, which in-turn may affect the quality and/or quantity of the overall metabolites. The primary purpose of this thesis was to evaluate the phytochemistry of the whole leaf of Aloe succotrina Lam. spp. - a South African native plant - through a chromatographic spectroscopic approach-against available data accumulated for the cultivated population. Preliminary screening of the cru
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Cardoso, Cássia Regina Primila [UNESP]. "Atividade mutagênica e ativadora da resposta imune celular induzidas por Byrsonima crassa Niedenzu e Byrsonima intermedia A.Juss. (Malpighiaceae)." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/86621.

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Made available in DSpace on 2014-06-11T19:22:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-02-21Bitstream added on 2014-06-13T18:08:04Z : No. of bitstreams: 1 cardoso_crp_me_arafcf.pdf: 859101 bytes, checksum: dc8d0d66975b1493a8b7a5a2830d3074 (MD5)<br>Universidade Estadual Paulista (UNESP)<br>Considerando a pesquisa de novas moléculas farmacologicamente ativas, orientada pelo uso tradicional das plantas com finalidade terapêutica, o presente trabalho avaliou os efeitos genotóxicos e de ativação do sistema imunológico em duas espécies de plantas do gênero Byrsonima: Byrsonima cras
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Fang, Yi-Zao, and 方苡藻. "Bioactive Component Analysis of Ethyl Acetate Extract from Grifola frondosa." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/86949089297346398188.

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碩士<br>亞洲大學<br>生物科技學系碩士班<br>99<br>The aim of this study was to analyze bioactivities of components extracted from Grifola frondosa that was grown in environmental controlled cultivation conditions. Ultrasonic extraction was used to extract ground powder from dry fruit body of Grifola frondosa by n-hexane, ethyl acetate and 50% ethanol. The extraction efficiencies of various organic solvents were 1.60 ± 0.36%, 3.10 ± 0.17% and 22.90 ± 0.40% for n-hexane, ethyl acetate and 50% ethanol respectively. DPPH radical scavenging activity, reducing power and ferrous ion chelating activity assays were use
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Chang, Chih-Shiang, and 張智翔. "Study on the hypoglycemic effect of the ethyl acetate extract of Curcubita moschata fruit in animal models." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/43652146121745893153.

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碩士<br>國立屏東科技大學<br>生物科技系所<br>104<br>The fruit of Cucurbita moschata has been confirmed to contain hypoglycemic components, and which can be further concentrated by partitioning between ethyl acetate (EA) and water to distribute them to the EA layer. The purpose of this study is to investigate the hypoglycaemic effect of the EA extract in diabetic animal models. To establish type 2 diabetic models, mice were fed with high-fat diet to induce insulin resistance, followed by injection of streptozotocin (stz) to destroy the pancreatic cell. The mice were then fed with the EA extract of pumpkin for
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Lee, Chung-Ching, та 李重慶. "Investigation of α-glucosidase inhibitory compounds in ethyl acetate fraction of methanol extract from water extract residues of Chinese olive (Canarium album L.)". Thesis, 2019. http://ndltd.ncl.edu.tw/handle/7h9j99.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>107<br>α-glucosidase inhibitor, one of the interference used for diabetes treatment, can inhibit the activity of α-glucosidase to decompose starch, oligosaccharide or disaccharide into monosaccharides, thereby delaying the absorption of sugar and stabilizing postprandial blood glucose. Various α-glucosidase inhibitors in nature exhibit the ability for modulating blood sugar. Our previous studies display that ethyl acetate fraction of methanol extract from water extract residues of Chinese olive (Canarium album (Lour.) Raeusch.) (COE) has anti-inflammatory effect on m
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Hsu, Chih-Ying, and 徐志穎. "Effects of ethyl acetate fraction from adlay bran ethanolic extract on the growth of human breast cancer cell." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/41741742962927111035.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>98<br>In Taiwan, breast cancer is one of the most common malignancies in women. Epidemiological studies pointed out that female exposed to estrogen abnormally increased the incidence of breast cancer. However, phytoestrogen, a plant chemical with known estrogenic effects, can lower breast cancer risk. Phytosterols, a kind of phytoestrogens, including β-sitosterol and campesterol have anticancer and regulate the ability for estrogen expression. Adlay, an annual crop, has been reported with many health effect including anticancer. Previous researches indicated that man
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Huang, Chieh-Yu, and 黃潔妤. "Ethyl Acetate Fraction of Longan (Dimocarpus longan Lour.) Flower Water Extract Attenuates Metabolic Syndrome in Fructose-Fed Rats." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/45768511139497881745.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>97<br>Metabolic syndrome becomes an important issue recently. It has strong correlation with several chronic disease, for instance, diabetes and cardiovascular disease. The risk factors of metabolic syndrome contain abdominal obesity, hyperglycemia, dyslipidemia and hypertension. Previous study in our laboratory has shown that Longan (Dimocarpus Longan Lour.) flower had strong antioxidant activity in vitro. Furthermore, we also have demonstrated that Longan flower water extract (LFWE) can improve the symptoms of the metabolic syndrome in animal model. Therefore, the
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Kuo, Tse-Wei, and 郭澤瑋. "Preliminary study on the expression of peroxisome proliferator response element by ethyl acetate extract of algae and Echinodermata Crinoidea." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/42823815998055449385.

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碩士<br>國立中山大學<br>海洋生物研究所<br>97<br>PPAR (peroxisome proliferator activated receptors) is a transcription factor that regulates activity and transcription of enzymes of lipid metabolism and thought PPAR-PPRE (peroxisome proliferator activated receptors – peroxisome prolierator response element) interaction. Cell toxicity was also tested by (3-(4,5-dimethylthiaz ol-2-yl)-2,5-diphenyltetrazolium bromide (MTT assay)). The effects of ethyl acetate (EA) extracts of algae and Echinodermata sp. on PPRE-luciferase activity in Huh-7 cell and cell cytotoxicity were conducted. EA extracts of Gracilaria coro
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11

Chung, Cheng-Pei, and 鍾成沛. "Screening of Physiological Activities on Adlay Bran Ethanolic Extract and Investigation on Chemical Composition of Its Ethyl Acetate Fraction." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/88892966084185824824.

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博士<br>國立臺灣大學<br>食品科技研究所<br>99<br>Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) is recorded as diuric, antitumor, anti-diabetes and stomachic agent. Edible parts of adlay seeds, dehulled adlay (DA), are composed of adlay bran (AB) and endosperm, and are regarded as food and medicine in Eastern world. DA was reported to possess anti-proliferative, anti-allergic, and anti-inflammatory activities, but it is still insufficient of its chemical composition. In the present study, DA ethanolic extract (DAE), AB ethanolic extract (ABE), and polished adlay ethanolic extract (PAE) were prepared, and sc
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12

Chang, En-Tzu, and 張恩慈. "Ethyl Acetate Extract of Sterculia nobilis Induces Apoptosis of Triple Negative Breast Cancer Cells Through the Overexpression of Apoptosis Inducing Factor." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/79589626957427488929.

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碩士<br>國立中興大學<br>生物化學研究所<br>101<br>In previous studies at our laboratory, we found that the Ethyl acetate extract, isolated from shell of pod of Sterculia nobililis (EPSN), can induce the apoptosis of human triple-negative breast cancer cell line BT-20 through the regulation of apoptosis-inducing factor (AIF) in caspase-independent pathway. In this study, we used EPSN to treat BT-20 cells for cytotoxicity test (48 Hr IC50:40-50 μg/mL) and to investigate how does AIF regulate the mechanism of apoptosis in cancer cells. The results of Western blotting analysis revealed that, in both BT-20 an
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13

Hsu, Hsing-Hua, and 許倖華. "Preventive effects of ethyl acetate fraction of adlay bran ethanolic extract on DMH-induced preneoplastic lesions of colon in F344 rats." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/07620761844150663718.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>96<br>Malignant neoplasm is the first cause of ten leading causes of death in 2007 in Taiwan and colorectal cancer is the third cause of cancer death in Taiwan. Epidemiological studies have indicated that colorectal cancer is strongly associated with diet, and thus the occurrence of colorectal cancer may be prevented by dietary modification. Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) is a grass crop used in traditional Chinese medicine and as a nutritious food. It has been reported that adlay pocesses anti-inflammatory and anti-tumor activity. In animal model,
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Hong, Yong-Han, and 洪永瀚. "Study on ameliorative effects of the ethyl acetate extract of alfalfa sprouts on disease course of MRL-lpr/lpr autoimmune-prone mice." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/57971933872300451298.

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博士<br>國立臺灣大學<br>微生物與生化學研究所<br>96<br>The purpose of this study was to investigate the effect of plant food components sample possessing the abilities of anti-inflammation, Th1/Th2 immune regulation, and selective estrogen receptor modulator (SERM) on the autoimmune-prone disease in MRL-lpr/lpr female mice. First, in primary cell culture test, potential plant food components which could inhibit LPS-stimulated pro-inflammatory cytokines, IL-1β, IL-6 and TNF-α, secretion from peritoneal macrophages of BALB/c mice were screened out. These potential food components were subsequently tested (per oral
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Tsai, You-Lun, and 蔡侑倫. "Effect of Momordica charantia L. and it’s ethyl acetate extract on serum and liver inflammatory markers in LPS induced acute inflammation model." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/65866331702516139705.

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碩士<br>國立臺灣大學<br>生化科技學系<br>100<br>Effect of sample on cytokines secretion of macrophage in vitro and LPS-induced acute inflammatory mice model are often used to screen sample with inflammatory modulation effect. Many researchs has revealed that wild bitter gourd (Momordica charantia Linn. var. abbreviata ser) has anti-inflammatory potential. The main purpose of this study is to analyze the effect of wild bitter gourd (Hualian NO.4 and NO.4, H3- and H4- respectively) on inflammation. Analyzing the effect of H3- and H4- bitter gourd extracts on LPS-stimulated Raw 264.7 cells, etanol extract(-EtOH
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Chien-Cheng and 江建成. "Rubus idaeus L. Ethyl Acetate Extract Reverses Epithelial-to-Mesenchymal Transition and Suppresses Cell Invasion and Protease Activities in Human Lung Cancer Cells." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/47958521739167421592.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>100<br>The epithelial-to-mesenchymal transition (EMT) in lung cancer cells is considered pre-requisite for acquiring invasive/migratory phenotype, and subsequent metastasis. In the present study, we extracted raspberry Rubus idaeus L. with methanol (RIME), chloroform (RICE), ethyl acetate (RIEE), n-butanol (RIBE), and water (RIWE). Our results showed that RIEE, which contained polyphenols including gallic acid, protocatechuic acid, epigallocatechin, methyl gallate, epicathchin, epigallocatechin gallate, rutin, epicatechin-3-gallate, and naringin, treatment signifi
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I-Hsien and 陳宜嫺. "The phenolics stability in cranberry juice and the repairment of the ethyl acetate extract and its separated fractions on damaged ARPE-19 cells irradiated by blue light." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/86047468219631770590.

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碩士<br>中山醫學大學<br>營養學研究所<br>96<br>Cranberry shows high antioxidation and biological activities, including anticancer, prevention of cardiovascular disease, prevention of urinary tract infection, prevention of gastric ulcer and so on. Cranberry contains abundant phenolics. Thus this study was focused on the storage stability of phenolics in cranberry and its effect on age-related macular degeneration(AMD). The results showed that the phenolics in cranberry would reduced. The free quercetin showed the best stability. And the flavonoids and proanthocyanidins were the second. The total phenolics sho
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Yu-Ju and 楊玉如. "Effects of Taiwanese yam (Dioscorea alata L. cv. Tainung No. 2) and its ethyl-acetate extract on the morphology of intestinal mucosa cells in ovariectomized female Balb/c mice." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/43986197604669221198.

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碩士<br>中山醫學大學<br>營養學研究所<br>96<br>The main purpose of this study was to investigate the effects of Dioscorea alata L. cv. Tainung No. 2 and its ethyl-acetate extract on the morphology of villi and proliferation of intestinal mucosa cells in ovariectomized female Balb/c mice. Mice were sham-operated or ovariectomized (OVX) at age of 8 weeks and were fed experimental diets after 3 days. Sham-operated mice (sham) were fed control diet (AIN-93G with corn oil) while OVX mice were randomly allocated into OVX (control diet), yam (63 g yam powder/100 g diet), yam extract (2 mg/g diet), genistein (200 mg
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Liu, Chia-Yu, and 劉家余. "Anti-inflammatory effects of ethyl acetate fractions from adlay bran extracts." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/36661597515831721671.

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碩士<br>臺灣大學<br>食品科技研究所<br>98<br>Adlay (Coix lachryma-jobi L.var. ma-yuen Stapf.) bran has been reported that possesses many physiological activities such as immune modulation, anti-inflammation, and antitumor. Our laboratory desires to develope a product that possesses the effects of anti-inflammation, antitumor, and attenuating the side effects of radiotherapy. The aim of this study is to compare the adlay bran ethanolic extract (ABE) and adlay bran ethyl acetate extract (ABEa) that were respectively partitioned into n-hexane, ethyl acetate, n-butanol, and water fractions for the anti-inflammt
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Kuo, Po-Tsun, and 郭柏村. "Studies on Antioxidative Components and Hypoglycemic Regulation of Ethyl Acetate Extracts from Alpinia officinarum Rhizome." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/51235747003652071824.

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碩士<br>東海大學<br>食品科學系<br>100<br>Diabetes is associated with deficiencies in insulin secretion or action. Excess reactive oxygen species are built up with chronic hyperglycemia, and are subsequently contributing to oxidative stress and complications. Antioxidants have important roles in disorders involving oxidative stress. Rhizome of Alpinia officinarum, an herbaceous plant of Zingiberaceae family, has long been used in traditional Chinese medicine. Previous studies have demonstrated that A. officinarum have antioxidant, anticancer, anti-nociceptive, anti-inflammatory and antiemetic activities.
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Lin, Nien-Ying, and 林念穎. "Studies on Antioxidative Components from n-Hexane and Ethyl Acetate Extracts of Rubia cordifolia L. Root." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/80389700537027765967.

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碩士<br>東海大學<br>食品科學系<br>97<br>The proximate composition and active components in extract of root of Rubia cordifolia were investigated in this study. Compositional analysis of dry root showed that the root contains carbohydrate 70.47%, ash 12.44%, crude protein 7.19%, crude fat 1.09% and moisture 8.81%. The antioxidative activities of n-hexane, ethyl acetate and methanol extract from six species of Chinese crude drugs were measured with ferricthiocyanate assay and compared to those of α-tocopherol and BHA. The results indicated the presence of remarkable antioxidative substance in n-hexane and
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Ma, Hao-Ting, and 馬浩庭. "Studies on the Antioxidant, Acetylcholinesterase Inhibitory Activities and Neuroprotective Effect of Glechoma hederacea Ethyl Acetate Extracts." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/18671424291820649696.

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碩士<br>靜宜大學<br>食品營養學系<br>104<br>Alzheimer’s disease is the most common neurodegenerative disease. Many studies have indicated that Alzheimer’s disease was related to neurotransmitter acetylcholine content. Recently, there is an increasing interest in the study how to protect nerve cells and improve the neurodegenerative disease. Glechoma hederacea belongs to the Lamiaceae family, is used for medication purpose widely and possesses several health benefits. This study was aimed to evaluate the effects of the crude extract (HWG, GH50, GH95) and partitioned fractional extract (EA, n-butanol, H2O) o
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Wu, Po-Kuan, and 吳柏寬. "Momordica charantia Extracts after Ethyl Acetate andEthyl Alcohol Extractions Inhibit Proliferation andMigration of Lung Cancer Cell Lines." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/34436384880911322094.

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碩士<br>國立臺灣大學<br>解剖學暨細胞生物學研究所<br>100<br>The fatality rate of lung cancer is the highest among all kinds of cancer in Taiwan. It has been demonstrated that bitter melon (Momordica charantia) extracts (BMEs) can inhibit the proliferation of breast cancer and prostate cancer cell line. We use four different “ethyl acetate-ethyl alcohol (Et-EA)” BMEs to treat human lung carcinoma cell lines CL1-0 and CL1-5 and investigate the effects of BMEs on these cell lines. The four down-streamed Et-EA BMEs used are pure water extract [BME-A], 50% methanol extract [BME-B], 100% acetone extract [BME-C] and acid
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Chen, Chi-Hsien, and 陳季賢. "Rubus idaeus L. Ethyl Acetate Extracts Promote E-cadherin via Downregulation of Snail-1 in Human Lung Adenocarcinoma Cells and Suppress Tumor Growth in Vivo." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/96816868103548740392.

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碩士<br>中山醫學大學<br>生化微生物免疫研究所<br>104<br>Lung cancer is the leading cause of cancer mortality in Taiwan and worldwide. At least 80% of lung cancer is non-small cell lung cancer (NSCLC) which is further divided histologically into adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Adenocarcinoma is the most common type of lung cancer. Metastases are the main cause of death from lung cancer. Carcinoma cells undergo epithelial-mesenchymal transition (EMT) to invade and disseminate from the primary tumor, leading to poor prognosis in lung cancer patients. Rubus idaeus L. is a woody pla
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Chen, Hsin-Ying, and 陳心瀅. "Studies of the polyphenol compounds in adlay hull and ethyl acetate and n-butanol subfraction of adlay bran methanol extracts on the inhibitory effect of tyrosinase activity and on scavenging effect of free radical." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/51282657013298844699.

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