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1

Beer, Tomasz M. Cancer clinical trials: A commonsense guide to experimental cancer therapies and clinical trials. DiaMedica Pub., 2012.

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2

Finn, Robert. Cancer clinical trials: Experimental treatments & how they can help you. O'Reilly, 1999.

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3

Patel, Shilpesh S. Handbook of cardiovascular clinical trials. Churchill Livingstone, 1997.

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4

Rothmann, Mark D. Design and analysis of non-inferiority trials. Chapman & Hall/CRC, 2011.

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5

P, Schuster Daniel, and Powers William J. MD, eds. Translational and experimental clinical research. Lippincott Williams & Wilkins, 2005.

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6

P, Griffin J., and O'Grady John Professor, eds. The textbook of pharmaceutical medicine. 5th ed. Blackwell, 2005.

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7

P, Griffin J., O'Grady John Professor, and D'Arcy P. F, eds. The textbook of pharmaceutical medicine. 3rd ed. Queen's University of Belfast, 1998.

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8

Mark, Chang, ed. Adaptive design methods in clinical trials. 2nd ed. Taylor & Francis, 2012.

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9

Griffin, J. P. The textbook of pharmaceutical medicine. 6th ed. Wiley-Blackwell, 2009.

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10

P, Griffin J., ed. The textbook of pharmaceutical medicine. 6th ed. Wiley-Blackwell, 2009.

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11

Williams, E. R. Experimental design and analysis for use in tree improvement. CSIRO, 1994.

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12

P, Griffin J., ed. The textbook of pharmaceutical medicine. 6th ed. Wiley-Blackwell, 2009.

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13

P, Griffin J., ed. The textbook of pharmaceutical medicine. 6th ed. Wiley-Blackwell, 2009.

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14

J, Davis R., ed. Design and analysis of an international experimental network: Legume inoculation trials in the NifTAL Project : the Inlit experience. Hawaii Institute of Tropical Agriculture and Human Resources, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, 1985.

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15

1928-, Mann Ronald D., Rawlins Michael D, and Auty R. M. 1947-, eds. A Textbook of pharmaceutical medicine: Current practice. Parthenon Pub. Group, 1993.

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16

1941-, Peace Karl E., ed. Biopharmaceutical statistics for drug development. M. Dekker, 1988.

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17

Mazoni, Lisa, and Giuseppe Scutellà. SceKspir al BeKKa: Romeo Montecchi dietro le sbarre dell'Istituto Penale Minorile Beccaria. Edizioni Clichy, 2020.

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18

1923-, Shepherd Michael, and Sartorius N, eds. Non-specific aspects of treatment. Published on behalf of the World Health Organization by H. Huber, 1989.

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19

Mark, Chang, ed. Adaptive design methods in clinical trails. Chapman & Hall/CRC, 2007.

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20

Schechter, Martin T. Open arms and alternative clinical trial designs : report =: Essais à option libre et autres plans d'essais cliniques : rapport. Health and Welfare Canada = Santé et bien-être social Canada, 1990.

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21

Hill, David E. Specialty melon trials. Connecticut Agricultural Experiment Station, 1995.

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22

G, Gauch Hugh. Statistical analysis of regional yield trials: AMMI analysis of factorial designs. Elsevier, 1992.

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23

Youngen, John A. Jerusalem artichoke trials in Southern Oregon. Agricultural Experiment Station, Oregon State University, 1992.

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24

Moxon, P. R. A. Gundogs: Training and field trials. Popular Dogs, 1986.

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25

Rosselló, J. M. Elena. Technical guidelines for field variety trials. Food and Agriculture Organization of the United Nations, 1993.

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26

Briscoe, C. Buford. Field trials manual for multipurpose tree species. 2nd ed. Winrock International Institute for Agricultural Development, 1990.

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27

Briscoe, C. B. Field trials manual for multipurpose tree species. Edited by Adams Norma 1953-. Winrock International Institute for Agricultural Development, 1989.

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28

United, States Congress House Committee on Small Business Subcommittee on Regulation Business Opportunities and Technology. Problems in securing informed consent of subjects in experimental trials of unapproved drugs and devices: Hearing before the Subcommittee on Regulation, Business Opportunities, and Technology of the Committee on Small Business, House of Representatives, One Hundred Third Congress, second session, Washington, DC, May 23, 1994. U.S. G.P.O., 1994.

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29

United States. Congress. House. Committee on Small Business. Subcommittee on Regulation, Business Opportunities, and Technology. Problems in securing informed consent of subjects in experimental trials of unapproved drugs and devices: Hearing before the Subcommittee on Regulation, Business Opportunities, and Technology of the Committee on Small Business, House of Representatives, One Hundred Third Congress, second session, Washington, DC, May 23, 1994. U.S. G.P.O., 1994.

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30

Susan, Tonascia, ed. Clinical trials: Design, conduct, and analysis. Oxford University Press, 1986.

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31

Borowsky, Beth, and Cristina Sampaio. Experimental Therapeutics. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0017.

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Bringing safe and effective treatments to patients with Huntington’s disease (HD) will require evaluation in properly designed and conducted clinical trials. Such clinical trials will require appropriate tools and practices, including therapeutics, patient registries, biomarkers, endpoints, trial design, and analysis tools. This chapter provides insight into the advances being made in each of these areas and highlights the challenges remaining. Lessons learned from prior HD trials as well as from trials in other neurodegenerative diseases affect our view of future HD clinical development. With
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32

Experimental conversations: Perspectives on randomized trials in development economics. The MIT Press, 2016.

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33

Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2024.

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34

Banerjee, Abhijit V. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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35

Banerjee, Abhijit V. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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36

Ogden, Timothy N. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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37

Brooke, Mike. Trials and Errors: Experimental UK Test Flying in The 1970s. History Press Limited, The, 2015.

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38

Cancer clinical trials: Experimental treatments & how they can help you. O'Reilly, 1999.

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39

Chang, Mark, and Shein-Chung Chow. Adaptive Design Methods in Clinical Trials (Biostatistics). Chapman & Hall/CRC, 2006.

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40

Shannon, William, Daniel P. Schuster, William J. Powers, Mario Castro, and Jeffrey E. Saffitz. Translational and Experimental Clinical Research. Lippincott Williams & Wilkins, 2005.

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41

Hallberg, Kelly, Coady Wing, Vivian Wong, and Thomas D. Cook. Experimental Design for Causal Inference: Clinical Trials and Regression Discontinuity Designs. Oxford University Press, 2013. http://dx.doi.org/10.1093/oxfordhb/9780199934874.013.0012.

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42

Finn, Robert, and Linda Lamb. Cancer Clinical Trials: Experimental Treatments and How They Can Help You. O'Reilly Media, Incorporated, 1999.

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43

Rothmann, Mark D., Brian L. Wiens, and Ivan S. F. Chan. Design and Analysis of Non-Inferiority Trials. Taylor & Francis Group, 2016.

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44

Hershberger, Scott L. Multivariate Clinical Trials For Randomized Experiments In The Behavioral Sciences. Psychology Press, 2011.

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45

Robb, Sheri L., and Debra S. Burns. Randomized Controlled Trials in Music Therapy. Edited by Jane Edwards. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199639755.013.14.

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Randomized controlled trials (RCTs) are experiments that compare two or more groups of participants, and participants are assigned to groups based on chance. Groups include an experimental intervention group that is being compared to a treatment as usual, a low dose or attention control condition, and/or a comparative treatment group. The purpose of randomization is to equalize groups on both known and unknown characteristics that may influence the outcome and the effectiveness of the intervention. This chapter describes how music therapists have used RCTs to demonstrate the effectiveness of m
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46

Clinical trials in oncology. 3rd ed. CRC Press, 2012.

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47

Miksza, Peter, and Kenneth Elpus. Design and Analysis of Experimental Research I. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199391905.003.0008.

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This chapter builds on the previous chapter by elaborating from theories of causal knowledge presented earlier to practical considerations for the design, execution, and analysis of randomized experiments and randomized controlled trials in music education research. The straightforward statistical analysis of the two-group experimental designs is explained through the t test. The analysis of variance technique is explained for the analysis of experimental and quasi-experimental data involving more than two groups. The chapter closes with a discussion of the analysis of data arising from experi
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48

Vanderschueren, S. Thrombolytic Properties of Recombinant Staphylokinase in Experimental Animal Models in Clinical Trials. Leuven University Press, 1996.

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49

Chernick, Michael R., and Kenneth N. Anderson. Introduction to Adaptive Designs with Applications to Clinical Trials Using R. Wiley & Sons, Incorporated, John, 2019.

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Chernick, Michael R., and Kenneth N. Anderson. Introduction to Adaptive Designs with Applications to Clinical Trials Using R. Wiley & Sons, Incorporated, John, 2019.

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