Gotowe bibliografie tematyczne / Fenofibric Acid

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Gotowa bibliografia na temat „Fenofibric Acid”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Fenofibric Acid"

Hoàng, Việt Dũng, Quang Anh Lương, Hòa Bình Nguyễn та ін. "NGHIÊN CỨU THIẾT LẬP CHUẨN ACID FENOFIBRIC". Tạp chí Y Dược học Cần Thơ, № 83 (25 січня 2025): 60–67. https://doi.org/10.58490/ctump.2025i83.3327.

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Đặt vấn đề: Chuẩn acid fenofibric là yêu cầu bắt buộc trong một số phương pháp phân tích (như HPLC, GC, LC_MS/MS) để kiểm tra chất lượng nguyên liệu và thành phẩm chứa acid fenofibric, do vậy thiết lập chất chuẩn acid fenofibric là yêu cầu cấp thiết ở Việt Nam. Mục tiêu nghiên cứu: Xây dựng tiêu chuẩn cơ sở và thiết lập chuẩn thứ cấp của acid fenofibric được tổng hợp tại Việt Nam. Đối tượng và phương pháp nghiên cứu: Acid fenofibric được tổng hợp bằng cách thủy phân ester fenofibrat trong môi trường base (NaOH) và tinh chế bằng phương pháp thông dụng. Cấu trúc sản phẩm được xác định bằng: IR,

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Suhery, Wira Noviana, Nofriyanti, and Annisa Permatasari. "PENGARUH TEKNIK LIQUISOLID MENGGUNAKAN TRANSCUTOL® HP TERHADAP DISOLUSI ASAM FENOFIBRAT." Jurnal Penelitian Farmasi Indonesia 12, no. 2 (2023): 104–10. http://dx.doi.org/10.51887/jpfi.v12i2.1905.

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Kelarutan merupakan salah satu parameter yang dapat mempengaruhi ketersediaan hayati obat. Obat-obatan dengan kelarutan yang rendah membutuhkan dosis tinggi untuk mencapai konsentrasi oral terapeutik. Asam fenofibrat adalah obat yang memiliki kelarutan dalam air yang rendah dan permeabilitas yang tinggi. Salah satu cara untuk mengatasi masalah kelarutan adalah dengan teknik liquisolid. Penelitian ini bertujuan untuk mengetahui pengaruh teknik liquisolid asam fenofibrat terhadap disolusinya. Formulasi dengan teknik liquisolid dibuat dengan jenis dan jumlah yang bervariasi menggunakan pelarut Tr

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Yang, Lily P. H., and Gillian M. Keating. "Fenofibric Acid." American Journal Cardiovascular Drugs 9, no. 6 (2009): 401–9. http://dx.doi.org/10.2165/11203920-000000000-00000.

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Rath, Nigam P., Wahajul Haq, and Ganesaratnam K. Balendiran. "Fenofibric acid." Acta Crystallographica Section C Crystal Structure Communications 61, no. 2 (2005): o81—o84. http://dx.doi.org/10.1107/s0108270104032573.

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Anggraini, Deni, Gressy Novita, and Intan Wulandari. "IMPROVED SOLUBILITY NOVEL MULTICOMPONENT CRYSTALS OF FENOFIBRIC ACID-ACETYLSALISYLIC ACID." Medical Sains : Jurnal Ilmiah Kefarmasian 10, no. 1 (2025): 89–98. https://doi.org/10.37874/ms.v10i1.1690.

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Solubility is an important physicochemical property of active pharmaceutical ingredients. Poor water solubility of active pharmaceutical ingredients leads to low bioavailability; therefore, efforts are needed to improve the solubility of active pharmaceutical ingredients. The goal of this study was to prepare and characterize novel multicomponent crystals of fenofibric acid (FA) using acid acetylsalicylic (ACE) as a coformer and to evaluate the solubility enhancement when prepared for multicomponent crystal formation. Solid characterization of the novel multicomponent crystals was performed us

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Dubey, Sunil K., Manoj S. Tomar, Anil Kumar Patni, Arshad Khuroo, Simrit Reyar, and Tausif Monif. "Rapid, Sensitive and Validated Ultra-Performance Liquid Chromatography/Mass Spectrometric Method for the Determination of Fenofibric Acid and its Application to Human Pharmacokinetic Study." E-Journal of Chemistry 7, no. 1 (2010): 25–36. http://dx.doi.org/10.1155/2010/726124.

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The first, rapid and sensitive ultra performance liquid chromatography mass spectrometric method for the determination of fenofibric acid, the active metabolite of fenofibrate, a lipid regulating agent, in human EDTA plasma has been developed and validated using fenofibric d6 acid as internal standard and Waters LC-MS/MS. Negative ions of fenofibric acid and fenofibric d6 acid were detected in multiple reaction-monitoring (MRM) mode. The method was validated over a concentration range of 0.176 μg/mL to 19.837 μg/mL (r ≥ 0.99). It took only 1.5 minute to analyse a sample. Intra- and inter-run p

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Saurav, Alok, Manu Kaushik, and Syed M. Mohiuddin. "Fenofibric acid for hyperlipidemia." Expert Opinion on Pharmacotherapy 13, no. 5 (2012): 717–22. http://dx.doi.org/10.1517/14656566.2012.658774.

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Kim, Tae. "Determination of Fenofibric Acid in Rat Plasma and its Application to a Comparative Pharmacokinetic Study of JW322 and Fenofibrate." Drug Research 67, no. 09 (2017): 534–38. http://dx.doi.org/10.1055/s-0043-109243.

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AbstractIn this study, a sensitive and reliable method for the quantitation of fenofibric acid in rat plasma was developed and validated using high performance liquid chromatography (HPLC). The plasma samples were prepared by deproteinization, and sildenafil was used as an internal standard. Chromatographic separation was achieved using a reversed-phase (C18) column. The mobile phase, 0.02 M ammonium acetate buffer:acetonitrile (35:65, v/v), was run at a flow rate of 1.0 mL/min, and the column eluent was monitored using an ultraviolet detector at 280 nm at room temperature. The retention times

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Bala, Vishnu Priya Mukkala *. Gopala Krishna Murthy Talasila and Prameela Rani Avula. "DEVELOPMENT OF FENOFIBRIC ACID DELAYED RELEASE PELLETS: OPTIMIZATION OF PROCESS VARIABLES IN FLUID BED PROCESS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 02 (2018): 1207–18. https://doi.org/10.5281/zenodo.1188922.

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The objective of the present study was to optimize the process of Fenofibric acid delayed release (DR) pellets. Wurster (Bottom spray fluid bed coating) process was employed to develop the Fenofibric acid DR pellets. This study assesses the impact of various process variables on drug layering by using statistical interpretation such as ANOVA. A face centered central composite design (CCD) was employed to study the effect of independent variables (product temperature, atomization air pressure, fluidization air volume and spray rate) on dependent variables (Fines, agglomerates, coating efficienc

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SUSHMA, P., and DR A. K. M. PAWAR. "Development of a New Validated Stability Indicating Method for Quantification of Fenofibric acid and Pitavastatin by Ultra Performance Liquid Chromatography." YMER Digital 21, no. 03 (2022): 287–99. http://dx.doi.org/10.37896/ymer21.03/32.

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The main objective of the present work is to develop an efficient, unique, reliable Ultra performance liquid chromatographic method for the simultaneous quantificaiton of Fenofibric acid and Pitavastatin in bulk and Pharmaceutical formulations. The Chromatographic separation of the selected combination of drugs was performed on a Kinetex C8 column (150mm x4.6mm, 2.6 µ) using an isocratic elution with a buffer containing 0.1% formic acid and acetonitrile at a ratio of 80:20 as a mobile phase with a flow rate of 0.5 mL/min at ambient temperature and wavelength at 266nm.The method produced reliab

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Rozprawy doktorskie na temat "Fenofibric Acid"

Kanavi, Matthildi. "In vitro biotransformation study of fenofibric acid." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-339501.

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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Student: Matthildi Kanavi Supervisor: PharmDr. Petra Malátková Title of diploma thesis: In vitro biotransformation study of fenofibric acid Fenofibric acid is a hypolipidemic agent that acts through PPARα and contributes to treatment of many types of dyslipidemias. It is the active metabolite of fenofibrate, but can be also administrated by itself. Concerning its metabolism, the majority of fenofibric acid is conjugated with glucuronic acid, while a minor amount yields a reduced metabolite. Re

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Jíchová, Šárka. "Úloha metabolitů kyseliny arachidonové v regulaci krevního tlaku u experimentálních modelů ANGII-dependentní formy hypertenze." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-436095.

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Introduction: Two major product groups originate from the arachidonic acid metabolic pathway of cytochromes P450: epoxyeicosatrienoic acid (EETs) and 19 and 20-hydroxyeicosatetraenoic acid (19- and 20-HETE). These metabolites play an important role in the regulation of blood pressure, inflammatory responses, regulation of sodium excretion and other crucial physiological processes. Hypothesis: Our studies were based on the hypothesis that abnormalities in the production and function of these cytochrome P450 metabolites significantly contribute to the pathophysiology of hypertension development,

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Streszczenia konferencji na temat "Fenofibric Acid"

Umar, Salman, Nedita Putri Bandaro, Deni Anggraini, and Erizal Zaini. "Multicomponent Crystal of Fenofibric Acid- Saccharin: Characterization and Antihyperlipidemic Effectiveness." In 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021). Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.211105.015.

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