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Rozprawy doktorskie na temat „Flagella (Microbiology)”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 3 marca 2023

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1

Wan, Yixin. "Modulation and synchronization of eukaryotic flagella." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708434.

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2

Moura, Cláudia de. "Identificação de novos antígenos flagelares e variação de fase em amostras de Escherichia coli isoladas de animais e alimentos." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317446.

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Orientador: Domingos da Silva Leite<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-17T10:33:43Z (GMT). No. of bitstreams: 1 Moura_Claudiade_D.pdf: 2791356 bytes, checksum: 7830cb1ece9ec9ac3c34c2794b264c93 (MD5) Previous issue date: 2010<br>Resumo: Escherichia coli é um membro comensal da microbiota de animais, porém podem causar doenças desde diarréias até sepses. A caracterização dos seus antígenos de superfície O (somático) e H (flagelar) auxilia na determinação de linhagens patogênicas dentro da espécie. Contudo, algum

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3

Pacheco, Sophia A. "Identification of Campylobacter jejuni secreted proteins." Pullman, Wash. : Washington State University, 2010. http://www.dissertations.wsu.edu/Thesis/Spring2010/s_pacheco_021610.pdf.

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4

Wang, Xiaoling. "Mechanical analysis and free energy construction of phase transition in bacterial flagellar filaments /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?MECH%202006%20WANGX.

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5

Steager, Edward Brian Kim MinJun. "Actuation and control of microfabricated structures using flagellated bacteria /." Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3132.

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6

Tiba, Monique Ribeiro. "Identificação de novos antigenos flagelares de Escherichia coli de origem humana." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316681.

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Orientador: Domingos da Silva Leite<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-14T15:47:58Z (GMT). No. of bitstreams: 1 Tiba_MoniqueRibeiro_D.pdf: 3934673 bytes, checksum: 211302f7129afd8376ba9096064a21c4 (MD5) Previous issue date: 2009<br>Resumo: Escherichia coli tem sido isolada, com certa freqüência, apresentando antígenos flagelares (H) que não são reconhecidos por nenhum dos anti-soros disponibilizado pelo mais importante centro de referência de E. coli, The International Escherichia and Klebsiella Centre (WHO) d

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7

Boateng, Lindsy R. "Determining the binding partners of PKA in the axoneme of Chlamydomonas reinhardtii flagella." Connect to online version, 2009. http://minds.wisconsin.edu/handle/1793/37450.

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8

Schreiber, Maria Fernanda. "Studying the host transcriptome and the role of flagella in infections mediated by Salmonella and other pathogens." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610270.

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9

Marshall, Joanna M. "The O-Antigen Capsule of Salmonella Typhimurium in Acute and Chronic Infection." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1385998769.

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10

Azevedo, Fátima da Piedade de Melo. "Inserção de epitopo heterólogo em diferentes regiões de flagelina bacteriana: influência na função flagelar e imunogenicidade." Universidade de São Paulo, 1997. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-09112015-150421/.

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Uma das estratégias mais promissoras para a biotecnologia de vacinas é o desenvolvimento de linhagens precisamente atenuadas, e que possam ser usadas como carregadoras de antígenos heterólogos. Mutantes de <i}>Salmonella Typhimurium têm sido extensivamente utilizados com essa fmalidade. A flagelina, monômero constituinte do filamento flagelar, vem sendo empregada como carregadora de antígenos heterólogos, inseridos na região central, hipervariável (região IV). Inserções nessa região são freqüentemente funcionais, e levam à exposição do epitopo na superfície do filamento. O presente trabalho ex

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11

Cerqueira, Otto Luiz Dutra. "Avaliação de diferentes sistemas de imunização que empregam a oncoproteína E7 do vírus papiloma humano tipo 16 (HPV 16) geneticamente fusionada à flagelina FliCd de Salmonella enterica sv. Muenchen." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-16072009-151128/.

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O câncer cervical é o segundo maior responsável por mortes atribuídas a câncer em mulheres e dados epidemiológicos tem demonstrado a associação entre a infecção do HPV e o desenvolvimento da neoplasia. Sabe-se que num dado momento da infecção pelo HPV, ocorre integração do genoma viral ao genoma da célula hospedeira e consequente hiperexpressão de dois oncogenes virais, E6 e E7, o que contribui fortemente para a transformação celular. O presente trabalho propõe o uso de vacinas terapêuticas expressando a oncoproteína E7 do HPV-16 geneticamente fusionada à porção amino terminal da flagelina Fli

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12

Santos, Paula Gomes dos. "Papel dos flagelos polar e lateral em cepas de Aeromonas caviae na formação de biofilme e aderência celular." Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=861.

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Aeromonas spp. são bactérias Gram negativas capazes de causar doenças intestinais e extra-intestinais. A virulência de algumas espécies do gênero já foi associada a diversos fatores, como a expressão de flagelos e conseqüente mobilidade bacteriana. Aeromonas caviae apresenta dois distintos sistemas flagelares, um deles responsável pela natação em meio líquido (swimming) onde está envolvido o flagelo polar, e outro associado ao deslizamento em superfícies sólidas ou viscosas (swarming), o qual participam flagelos laterais. A fim de avaliar a contribuição de ambos os flagelos no contexto da form

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13

Stoakes, Emily Anne. "Campylobacter jejuni : deciphering the role of F1hF in flagellar biogenesis." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/106465/.

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Campylobacter jejuni is one the leading causes of food poisoning in the UK. Motility in C. jejuni is key to its survival within the gut and other environments. Without the two flagella, one at either end of the cell, it is highly attenuated to cause disease. As the flagellar structure is imperative to Campylobacters lifestyle, studying the regulation of flagella synthesis is important. Unlike other bacteria, Campylobacter lacks a master regulator atop the flagella synthesis pathway. It does however, have an FlhF protein with a signal recognition particle (SRP) domain and GTPase activity whose

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14

Ayala, Claudia de Oliveira. "Sorologia de antígenos flagelares de amostras de Escherichia coli Enteropatogênicas (EPEC) e E. coli produtoras da Toxina de Shiga (STEC) isoladas de diferentes animais e análise comparativa do gene fliC por PCR-RFLP." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-02022010-100052/.

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A espécie Escherichia coli constitui um grupo de bactérias tipicamente não patogênicas e que fazem parte do trato intestinal de humanos e animais. As amostras são sorotipadas com base em seus antígenos de superfície O (somático), H (flagelar) e K (capsular). O antígeno flagelar correspondente ao filamento é formado pela polimerização da flagelina, codificada pelo gene fliC. O presente trabalho empregou a técnica de PCR-RFLP para analisar os padrões de antígenos flagelares de 112 amostras de EPEC e STEC. Quatorze amostras não amplificaram o gene fliC, 17 tiveram seu antígeno flagelar determinad

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15

Davis, Nicole J. "Investigating the Involvement of C. crescentus TipF in Flagellar Biogenesis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301697521.

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16

Benedikz, Elizabeth Kristin. "The effect of bacterial flagellin on virus infection." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7327/.

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Coinfection with bacteria and viruses is an understudied area of microbiology, despite its potential to modulate pathogen abundance and host survival. We investigated the effect of bacteria on virus infection and developed an in vitro system to study the first step: viral internalization. Our studies show that multiple bacterial species promote the entry of a diverse panel of viruses into lung and gut epithelial cells. Bacteria expressing the toll-like receptor (TLR)5 agonist, flagellin, are most efficient at inducing viral uptake and studies using recombinant flagellin or aflagellate bacteria

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17

Molero, Andrades Raquel Ángeles. "Implicación de la glicosilación en el ensamblaje del flagelo y las fimbrias de Aeromonas hydrophila AH-1." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/146253.

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El género Aeromonas está constituido por bacilos gram negativos y comprende patógenos de animales poiquilotermos y oportunistas en humanos. La virulencia de Aeromonas hydrophila AH-1 es multifactorial, siendo el lipopolisacárido (LPS), el flagelo (polar y lateral) y la lámina S importantes factores de patogenicidad. La mutación del gen wbpL, implicado en la biosíntesis del antígeno O del LPS, da lugar a la pérdida de antígeno O, una bajada en el peso molecular de las flagelinas polares y la aparición de fimbrias en la superficie bacteriana. Se procedió a estudiar si las flagelinas polares y la

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18

Cicirelli, Elisha M. "Bacterial quorum-sensing in the marine sponge environment implications on motility and flagellar biosynthesis /." [Bloomington, Ind.] : Indiana University, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3297116.

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Thesis (Ph.D.)--Indiana University, Dept. of Biology, 2007.<br>Title from dissertation home page (viewed Sept. 29, 2008). Source: Dissertation Abstracts International, Volume: 69-02, Section: B, page: 0818. Adviser: Clay Fuqua.

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19

Lim, Ren Chong. "Application of magnetic torque on the bacterial flagellar motor." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:2f18fdff-e876-4be6-8ac2-c8281a4a905a.

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There is a strong need to develop a mechanical method to apply external torque to the bacterial flagellar motor. Such a method will allow us to probe the behaviour of the motor at a range of different speeds under different external conditions. In this thesis, I explored various methods to deliver torque at the single-molecule level, in particular the use of angular optical trapping and magnetic tweezers. I have identified rutile particles as suitable handles for use in angular optical trapping due to their high birefringence. Further progress was not achieved using angular optical trapping du

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20

Blackwell, Gemma. "Regulation of flagellin glycosylation genes in Campylobacter jejuni : influence of NssR, the nitrosative stress response regulator." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/639/.

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Campylobacter jejuni is one of the leading causes of food borne illness worldwide; the main cause of infection is the consumption of undercooked, contaminated poultry. Motility, mediated by single polar flagella, is necessary for Campylobacter virulence. The flagellin proteins are extensively glycosylated in C. jejuni with pseudaminic acid and related derivatives; glycosylation is required for flagella filament formation. The flagellin glycosylation locus in C. jejuni NCTC11168 comprises 50 genes, 50% are potentially involved in glycan biosynthesis and others are hypothetical; the regulatory m

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21

Malandrin, Laurence. "Les protéines de surface de pseudomonas syringae (sensu lato) : description, variabilité et application taxonomique." Angers, 1995. http://www.theses.fr/1995ANGE0015.

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Pseudomonas syringae est une bactérie phytopathogène qui provoque des dégâts de gravité variable sur une large gamme d'hôtes. Les 57 pathovars qui la subdivisent viennent d'être redistribués en cinq espèces génomiques qu'aucun critère phénotypique ne permet de caractériser. Nous avons étudié les protéines de surface présentes chez ces bactéries et tente d'évaluer leur potentiel taxonomique. Deux sérotypes flagellaires, h1 et h2, identifiables en immunofluorescence et en immunotransfert, sont distingués pour les souches de p. Syringae. H1 et h2 montrent une distribution remarquablement homogène

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22

Karayanni, Héra. "Rôle des nanoflagellés hétérotrophes et des ciliés dans la régulation du pico- et nanoplancton photosynthétique et des bactéries en Atlantique NE et le recyclage de la matière organique." Aix-Marseille 2, 2004. http://www.theses.fr/2004AIX22063.

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23

Mazet, Muriel. "Culture in vitro et caractérisation d'enzymes hydrogénosomales chez Histomonas meleagridis, protozoaire flagellé parasite de gallinacés." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2007. http://tel.archives-ouvertes.fr/tel-00718217.

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Le protozoaire flagellé Histomonas meleagridis est responsable d'une maladie chez les oiseaux galliformes, nommée histomonose. La culture in vitro de ce parasite anaérobie est qualifiée d'agnobiotique car il y a présence d'une flore bactérienne non déterminée. L'identification des bactéries dans cette flore montre l'existence d'une flore très diversifiée. Des essais de culture axénique et monoxénique suggèrent que les bactéries sont essentielles au développement in vitro du parasite. Par des stratégies de PCR, RT-PCR et RACE-PCR, nous avons les gènes complets codant trois protéines intervenant

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24

Houry, Ali. "Rôle des flagelles et de la mobilité dans la formation de biofilms par Bacillus cereus." Paris 11, 2009. http://www.theses.fr/2009PA112369.

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Bacillus cereus est fréquemment associé à des toxi-infections alimentaires et peut être responsable de pathologies opportunistes sévères. La présence de B. Cereus dans les industries agro-alimentaires compromet la qualité et surtout la sécurité des produits finis. La capacité de B. Cereus à former des biofilms sur différentes surfaces, renforce sa persistance sur les équipements de production industrielle. Les travaux présentés dans cette thèse ont permis d'une part de caractériser la dynamique de formation du biofilm par B. Cereus et d'autre part, de mettre en évidence et de clarifier le rôle

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25

Vucica, Yvonne. "Insertional mutants of Chlamydomonas affecting the central pair apparatus of the flagellum." Thesis, 2002. https://eprints.utas.edu.au/22090/1/whole_VucicaYvonne2002_thesis.pdf.

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26

"Molecular interaction of flagellar export chaperone FliS and its interacting partner HP1076 in Helicobacter pylori." Thesis, 2010. http://library.cuhk.edu.hk/record=b6075073.

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A HP1076 null mutant has been constructed to provide a better understanding of the biological significance of HP1076 in H. pylori . The DeltaHP1076 mutant displays impaired motility and resistance to the antibiotic drug metronidazole. Using a proteomic study, an overall of 40 differentially expressing proteins involved in metabolism and pH homeostasis for bacterial survival, adhesion for colonization, virulence factor to gastric epithelial cells and antigenic proteins have been identified. The virulence factor, Cag pathogenicity island protein (Cag 26) and urease UreA and UreB are confirmed to

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27

Aagesen, Alisha M. "Investigating Vibrio parahaemolyticus interactions with the Pacific oyster, Crassostrea gigas." Thesis, 2012. http://hdl.handle.net/1957/35769.

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Vibrio parahaemolyticus is a Gram-negative, halophilic, human pathogenic bacterium ubiquitous in the marine environment. Like many Vibrio species, V. parahaemolyticus commonly associates with shellfish, particularly oysters. Ingestion of a raw or under cooked oysters contaminated with V. parahaemolyticus can cause gastroenteritis, which is typically self-limiting and rarely causes death. Globally, oyster production is highly lucrative, especially on the West Coast of the United States where approximately 60% of oyster production occurs each year. Outbreaks of V. parahaemolyticus can result

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28

Perera, Kalyani. "Characterisation of a secreted immunogenic protein, phase-1 flagellin (FliC) of Salmonella enterica subspecies enterica Brandenburg : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Microbiology at Massey University, Palmerston North, New Zealand." 2007. http://hdl.handle.net/10179/1450.

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Cell-envelope associated and secreted proteins of Salmonella are integral for host-pathogen interactions, and for the induction of protective immune responses. An array of exported proteins of S. Brandenburg was identified through constructing an expression library using alkaline phosphatase gene technology. A partial digest of S. Brandenburg strain S59 was cloned into the vector pJEM11, and expressed in E. coli. The DNA inserts from randomly selected alkaline phosphatase positive clones were sequenced, and the sequences were analysed using public databases to find the ones that may play a rol

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