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Rozprawy doktorskie na temat „Foot diseases”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 30 lipca 2024

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1

Du, Toit Leon Lourens. "Form and function of the rheumatoid foot." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/25632.

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Redmond, A. C. (Anthony C. ). "Foot posture in neuromuscular disease : development and evaluation of a novel method for quantifying change in foot posture using Charcot-Marie-Tooth disease as a clinical model." Phd thesis, Department of Paediatrics and Child Health, Faculty of Medicine, 2004. http://hdl.handle.net/2123/8077.

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Chen, Shih-Ping. "Epidemiology, pathogenesis and surveillance of pig adapted strain of foot and mouth disease in Taiwan /." Murdoch University Digital Theses Program, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20080813.104029.

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Hui, Kin-hi Raymond. "Molecular epidemiology of and vaccine development against foot-and-mouth disease virus in Hong Kong." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31548544.

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Sahle, Mesfin. "An epidemiological study on the genetic relationships of foot-and-mouth disease viruses in East Africa." Thesis, University of Pretoria, 2004. http://hdl.handle.net/2263/27222.

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Within East African countries many of the known infectious diseases of animals occur commonly and are poorly controlled. Foot-and-mouth disease (FMD) is one of the contagious viral diseases that has great impact on economic development both in terms of direct and indirect losses. The epidemiology of the disease is complex due to the presence of six of the seven serotypes and the presence of large numbers of both wild and domestic susceptible animals in the region. Decision-making to determine the importance of FMD control relative to the economic consequences and what FMD control strategies sh

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6

Lau, Ming-ho, and 劉明昊. "Risk factors of hand foot mouth diseases outbreaks in kindergartens inHong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42994901.

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7

Halleen, Francois. "Characterisation of Cylindrocarpon spp. associated with black foot disease of grapevine." Thesis, Stellenbosch : Stellenbosch University, 2005. http://hdl.handle.net/10019.1/21454.

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Dissertation (PhD (Agric))--University of Stellenbosch, 2005.<br>ENGLISH ABSTRACT: During the past few years a drastic reduction has been noted in the survival rate of grafted grapevines in nurseries, as well as in young vineyards in the Western Cape Province of South Africa. Circumstantial evidence suggested that Cylindrocarpon spp., which cause black foot disease of grapevine, were associated with this decline. Black foot disease of grapevine is a relatively new, and as yet poorly known disease affecting vines in various countries where grapevines are cultivated. Primary aims of this re

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8

Knight-Jones, Theo. "Field evaluation of foot-and-mouth disease vaccination in Turkey." Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618321.

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Lau, Ming-ho. "Risk factors of hand foot mouth diseases outbreaks in kindergartens in Hong Kong." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42994901.

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Biswal, Jitendra Kumar. "Evaluation of mucosal immunity in FMDV vaccinated and infected cattle." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572448.

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11

Landorf, Karl B., University of Western Sydney, College of Social and Health Sciences, and School of Exercise and Health Sciences. "Effectiveness of foot orthoses in the treatment of plantar fasciitis." THESIS_CSHS_EHS_Landorf_K.xml, 2004. http://handle.uws.edu.au:8081/1959.7/696.

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The aim of this thesis is to evaluate the short and long term effectiveness of foot orthoses in the treatment of plantar fasciitis.Three studies were undertaken, the first two informing the third. The aim of the first study was to establish prescription habits of Australian and New Zealand podiatrists in order to ascertain the most commonly prescribed foot orthoses. The second study was conducted to establish the most appropriate outcome measure to assess the effectiveness of foot orthoses in the treatment of plantar faciitis. The main study, a pragmatic single-blind randomised control trial,

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12

Hui, Lan-fong, and 許蘭芳. "Quality of life in patients with diabetic foot ulcer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45011771.

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Borley, Daryl W. "Epitope dominance studies with serotype O foot-and-mouth disease." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:4adc3373-1d89-41d9-b1ce-7d8cbb0e817a.

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Foot-and-mouth disease virus (FMDV) is an economically devastating and highly contagious livestock pathogen. It exists as seven serotypes, comprising numerous antigenically distinct subtypes. The large amount of antigenic heterogeneity has confounded attempts at developing broadly reactive vaccines. In order to overcome this issue the fundamentals of the interactions between the virus and the host humoral immune response must first be understood. Previous work in this area using monoclonal antibody (mAb) escape mutants has identified five antigenic sites for the O serotype and efforts have bee

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14

Slager-Bastos, Armanda Duarte. "Molecular epidemiology and diagnosis of SAT-type foot-and-mouth disease in southern Africa." Thesis, University of Pretoria, 2001. http://hdl.handle.net/2263/22866.

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Foot-and-mouth disease (FMD) is an economically devastating picornaviral disease affecting over 40 species of cloven-hoofed animals. The virus occurs as seven immunologically distinct serotypes which are characterized by high levels of intra- and intertypic variation. The three South African Territories (SAT) serotypes 1-3 are endemic to sub-Saharan Africa, a region where the epidemiology of the disease is particularly complex due to the presence of six of the seven serotypes, the role of wildlife in virus maintenance and the apparently higher levels of variation in the endemic serotypes. Thes

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15

Waters, Ryan Andrew. "Investigating novel aspects of FMDV pathogenesis in pregnant ovines, foetuses and neonatal lambs." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572483.

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16

Howard, Sally Claire. "Statistical estimation of epidemiological parameters relating to infectious disease." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365804.

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17

Mielke, Sarah Rebecca. "Environmental Persistence of Foot and Mouth Disease Virus and the Impact on Transmission Cycles in Endemic Regions." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1574079284530142.

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18

Hui, Kin-hi Raymond, and 許建熙. "Molecular epidemiology of and vaccine development against foot-and-mouth disease virus in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31548544.

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Kim, Hyeyoung. "The Role of Pastoralist Mobility in Foot-and-Mouth Disease Transmission in The Far North Region of Cameroon." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1469174270.

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20

Svedberg, Lena. "Cold feet in children with neurological disorders /." Gothenburg : Institute of Neuroscience and Physiology, Clinical Neuroscience and Rehabilitation, Sahlgrenska Academy, University of Gothenburg, 2009. http://hdl.handle.net/2077/21042.

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21

Agustí, Brisach Carlos. "Studies on the epidemiology of black-foot disease of grapevine in Spain." Doctoral thesis, Universitat Politècnica de València, 2013. http://hdl.handle.net/10251/27598.

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Las enfermedades de la madera se encuentran entre las patologías más dañinas que afectan al cultivo de la vid. El pie negro es una de las más destacadas, afectando a las plantas en vivero y en plantaciones jóvenes. Los agentes causales están incluidos dentro de los géneros Campylocarpon, ¿Cylindrocarpon¿, Cylindrocladiella e Ilyonectria. Éstos se caracterizan por ser habitantes del suelo y, se ha demostrado que permanecen en él, infectando al material de propagación cultivado en campos de vivero. La presencia de hongos asociados al pie negro en vivero, así como sus fuentes potenciales de inócu

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22

Landorf, Karl B. "Effectiveness of foot orthoses in the treatment of plantar fasciitis." Thesis, View thesis, 2004. http://handle.uws.edu.au:8081/1959.7/696.

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The aim of this thesis is to evaluate the short and long term effectiveness of foot orthoses in the treatment of plantar fasciitis.Three studies were undertaken, the first two informing the third. The aim of the first study was to establish prescription habits of Australian and New Zealand podiatrists in order to ascertain the most commonly prescribed foot orthoses. The second study was conducted to establish the most appropriate outcome measure to assess the effectiveness of foot orthoses in the treatment of plantar faciitis. The main study, a pragmatic single-blind randomised control trial,

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23

Zanoti, Márcia Diana Umebayashi. "Membranas de Celulose Bacteriana com anti-inflamatório Ibuprofeno para o tratamento de feridas crônicas /." Araraquara, 2017. http://hdl.handle.net/11449/148880.

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Orientador: Ana Maria Minarelli Gaspar<br>Coorientador: Sidney Jose Lima Ribeiro<br>Coorientador: Helena Megumi Sonobe<br>Banca: Marlus Chorilli<br>Banca: Rondinelli Donizetti Herculano<br>Banca: Carlos Alberto Fortulan<br>Banca: Eliana Cristina da Silva Rigo<br>Resumo: Feridas crônicas são multifatoriais e resultantes do processo de cicatrização inadequada, no qual não ocorre reparação tecidual ordenada e temporal, ou ainda, há ausência de restauração anatômica e funcional completa, comprometendo a vida cotidiana dos indivíduos. Para a melhoria da assistência à saúde destas pessoas, buscou-se

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Duffin, Anthony C. "Structural and functional changes in the feet of young people with Type I Diabetes Mellitus /." View thesis, 2002. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030724.100739/index.html.

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De, Souza Hebe Winifred. "Behaviour change through education in adult people with diabetes with regards to their footcare." Thesis, Queensland University of Technology, 1998. https://eprints.qut.edu.au/36592/1/36592_De%20Souza_1998.pdf.

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Diabetes mellitus is a complex metabolic disorder that lasts a life time and can damage a person's feet. Poorly controlled diabetes can lead to the chronic complications of macrovascular disease and peripheral neuropathy in the feet. Neglect of feet that have these complications can result in the serious consequences of ulceration, infection, gangrene and amputation. The medical, rehabilitation and direct hospital costs due to diabetes are considered to be high. Current literature documents evidence that a significant number of lower limb amputations caused by diabetes can be prevented.

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Česnulevičienė, Rūta. "Harmfulness of field pea (Pisum sativum L.) fungal diseases, their prevention and control." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20121123_125900-41231.

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Research objective and experimental tasks. The study was designed to explore the incidence and severity of root and foot rots and ascochyta blight in field pea crops and to identify the measures and practices for the prevention and control of the diseases caused by the pathogens of Ascochyta complex. Experimental tasks: - To identify the susceptibility of various field pea varieties to root and foot rots and ascochyta blight under different agro-ecological conditions. - To establish the effect of meteorological factors on the severity of root and foot rots and ascochyta blight in field pea cro

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27

Fleming, Peter J. S., and n/a. "Relationships between feral goats (Capra hircus) and domestic sheep (Ovis aries) with reference to exotic disease transmission." University of Canberra. Resource, Environmental & Heritage Sciences, 2004. http://erl.canberra.edu.au./public/adt-AUC20050714.142151.

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Merino sheep are the most numerous domestic livestock in Australia and feral goats are wide-spread and locally abundant in many of the regions where sheep are grazed. Foot and mouth disease (FMD) is a disease of ungulates that causes severe economic hardship to countries where outbreaks occur or where it has become endemic. In India, Africa, Greece and recently the United Kingdom and Eire, sheep and goats have been implicated in the spread and maintenance of FMD. In Australia, there are contingency plans (AUSVETPLANS) for dealing with an outbreak of FMD. Included in those plans are strategies

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Nguyen, Huong Xuan. "Factors influencing Hand-Foot-Mouth disease in the Mekong Delta Region in the Context of Climate Change and Potential Strategies to Improve Prevention and Control." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/391524.

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Climate-sensitive infectious diseases such as hand-foot-mouth disease (HFMD) are expected to increase with the changing climate, leading to a greater burden on population health. The extent to which the changes in climate can or will affect population health varies across regions, depending on specific climate characteristics and variability, and on the specific socio-economic and health infrastructure of each region. Hence, local regional-specific climate change adaptation measures needed to be based on an understanding of the health impacts at the regional level. This is particularly relevan

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Duffin, Anthony C., University of Western Sydney, of Science Technology and Environment College, and of Science Food and Horticulture School. "Structural and functional changes in the feet of young people with Type 1 diabetes mellitus." THESIS_CSTE_SFH_Duffin_A.xml, 2002. http://handle.uws.edu.au:8081/1959.7/408.

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Diabetes can affect the structure and function of the foot, resulting in severe limitation of mobility and reduction of life expectancy. Early warning signs include limited joint mobility (LJM), soft tissue changes, high plantar pressure (HPP), high pressure time integrals (P/TI) and plantar callus. These abnormalities were examined in 216 young people with diabetes and 57 controls. The fingers, toes, ankle subtalar and first metatarsophalangeal joints shows reduced motion and the plantar aponeurosis was thicker in diabetic subjects. Skin thickness was the same for diabetic and control subject

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陳鎮英. "跟痛症手法治療規律的文獻研究". HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/1036.

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Schmidt-Burbach, Jan. "Thermografische Ermittlung physiologischer Wärmeprofile und pedografische Untersuchungen an den Extremitäten sowie Haltungsanalysen beim Asiatischen Elefanten (Elephas maximus) in menschlicher Obhut." Doctoral thesis, Universitätsbibliothek Leipzig, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:15-20090626-071443-0.

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Im Zuge systematisch durchgeführter thermografischer Untersuchungen an 95 Asiatischen Elefanten in europäischen Zoos konnten physiologische Wärmeprofile aller nicht von Fußkrankheiten betroffener Elefanten erstellt werden. Um eine objektivere Befundung zu ermöglichen, wurden dafür definierte Messbereiche an den Füßen festgelegt und deren Temperaturdaten als Wärmekurven für jeden Zeh dargestellt. Es zeigte sich, dass die Bandbreite von Temperaturen gleicher Messbereiche starken individuellen Schwankungen unterliegt, weshalb eine Befundung nicht anhand absoluter Temperaturwerte erfolgen sollte.

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Sposeto, Rafael Barban. "Estudo radiográfico axial do antepé para a avaliação do alinhamento da cabeça dos metatarsais no plano coronal." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-05062018-134557/.

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INTRODUÇÃO: As alterações do comprimento relativo dos metatarsais no plano axial são consideradas por muitos autores uma causa de distribuição inadequada da carga durante a marcha, sobrecarregando as estruturas plantares do antepé, culminando com a metatarsalgia. A meta do tratamento cirúrgico dessa síndrome é estabelecer o alinhamento da fórmula metatarsal. Porém, muitos estudos evidenciam uma taxa de 15% de recidiva da metatarsalgia após a reconstrução do formato preconizado no plano axial, conduzindo a um questionamento sobre a importância do alinhamento das cabeças dos metatarsais no plano

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Walters, David Paul. "The prevalence of diabetic foot disease." Thesis, University of London, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320402.

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During a surveillance programme all the known diabetics (1150) were identified from a general population of 97,034 representing all patients registered with 10 general practices. A control group of 751 non-diabetic subjects were also drawn from the same general population. A single observer reviewed 1077 (93.6%) of the diabetics and 480 (69%) of the controls. Peripheral vascular disease was detected using doppler ankle/brachial pressure index in 20.6% (95% CI 18.2-23.0) of diabetics and 9.6% (95% CI 7.0-11.2) of controls. There was no significant difference between the prevalence in non-insuli

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Nayak, Arabinda. "Foot and mouth disease virus RNA replication." Thesis, University of Surrey, 2005. http://epubs.surrey.ac.uk/842873/.

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Infection of susceptible cells with foot and mouth disease virus (FMDV) results in multiplication of the RNA genome and assembly of mature virions. The entire process of genome replication is completed in a few hours and encompasses many intracellular events. Like other picornaviruses, FMDV uses a peptide primed RNA replication mechanism. The factors that are required to uridylylate each of the three FMDV VPg peptides and the role of the FMDV cis-acting replication element (cre) or 3B Uridylylation Site (bus) in VPg uridylylation have been determined. The native N-terminus of the FMDV 3Dpol en

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Foster-Cuevas, Mildred. "Immunodeterminants of foot-and-mouth disease virus." Thesis, University of Hertfordshire, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338562.

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Puig, Arturo. "Lipopeptide vaccines against foot and mouth disease." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428103.

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Kristjánsson, Guðjón. "Food antigen sensitivity in coeliac disease assessed by the mucosal patch technique /." Uppsala : Acta Universitatis Upsaliensis, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6020.

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Crutchley, Bushell Tamara. "A survey assessment of veterinarians to determine the level of preparedness for an infectious disease outbreak." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. http://www.mhsl.uab.edu/dt/2006p/bushell.pdf.

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Al-Azri, Masoud. "Modelling crop diseases for food security." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/44777/.

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Global crop production is affected by seasonal and climatic variations in temperature, rainfall patterns or intensity and the occurrence of abiotic and biotic stresses. Climate change can alter pest and pathogen populations as well as pathogen complexes that pose an enormous risk to crop yields and future food security. Crop simulation models have been validated as an important tool for the development of more resilient agricultural systems and improved decision making for growers. The Agricultural Production Systems Simulator (APSIM) is a software tool that enables sub-models to be incorporat

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Romberg, Megan Kara. "Research into two diseases of solanaceous crops in California : 1) characterization of potato early dying in Kern County, California. 2) phylogeny, host range and molecular detection of Fusarium solani f.sp. eumartii, causal agent of Eumartii wilt in potato, foot rot of tomato and stem rot of pepper /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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Cottam, Eleanor Myfanwy. "Micro-evolution of foot-and-mouth disease virus." Thesis, Connect to e-thesis. Move to record for print version, 2008. http://theses.gla.ac.uk/92/.

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Thesis (Ph.D.) - University of Glasgow, 2008.<br>Ph.D. thesis submitted to the Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, 2008. Includes bibliographical references. Print version also available.

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Lea, Susan Mary. "Structural studies on foot-and-mouth disease virus." Thesis, University of Oxford, 1993. http://ora.ox.ac.uk/objects/uuid:438dc0ae-b899-40fd-84dc-03d3fc1a537f.

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Foot-and-mouth disease viruses (FMDVs) constitute the aphthovirus genus of the Picornaviridae. The structures of Oi subtype viruses OiK and G67 have been solved and comparisons reveal the structural basis of monoclonal antibody escape mutations in G67. Escape mutations are seen to occur at surface-exposed residues and to provoke structural changes limited to the altered side chains. Comparisons of the structures of O<sub>1</sub> and O<sub>1</sub>BFS (Acharya et al., Nature 337, 709-716 (1989)) suggest that changes occurring 'in-the-field' in response to polyclonal antibody pressure may be subt

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Lazzarini, Peter A. "The burden of foot disease in inpatient populations." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/101526/1/Peter_Lazzarini_Thesis.pdf.

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This thesis examined the prevalence and factors associated with foot disease (ulcers, infections and ischaemia) in a representative Australian inpatient population. This research is the first to reveal the full extent of the foot (disease) print on our hospitals. It found firstly, that foot disease caused the hospitalisation of one in every 20 inpatients which would make it a top 10 cause of hospitalization in Australia. Secondly, it identified similar factors were associated with foot disease in both diabetes and non-diabetes inpatient populations. Finally, it recommended practical strategies

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Edacheril, Mathew. "Assessment of herd immunity to foot-and-mouth disease." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314315.

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Mahdi, Ali Jafar. "Foot and mouth disease in Iraq: strategy and control." Kansas State University, 2010. http://hdl.handle.net/2097/4620.

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Master of Science<br>Department of Diagnostic Medicine/Pathobiology<br>Gary A. Anderson<br>Foot-and-mouth disease (FMD) is a highly infectious viral disease of cattle, pigs, sheep, goats, buffalo, and artiodactyl wildlife species. Foot-and-mouth disease virus is endemic and periodic devastating epidemics have occurred and caused heavy economic losses in Iraq for a long time. The first official cases of FMD were recorded in 1937, while the first record of a specific FMD serotype in Iraq was serotype A in 1952. Other serotypes have been reported since then; serotypes O, SAT-1 and Asia1 were

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Cabral, Ana Cristina Garcia Pereira. "New insights in Ilyonectria black foot disease of grapevine." Doctoral thesis, ISA/UTL, 2012. http://hdl.handle.net/10400.5/5192.

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Doutoramento em Engenharia Agronómica - Instituto Superior de Agronomia<br>Considering the growing importance of black foot disease of grapevine, this study was aimed to deeply understand details on taxonomy, genetics, biology and pathological behaviour of its main causal agents, previously attributed mostly to Ilyonectria liriodendri and I. macrodidyma. A multi-gene analysis of a collection of Ilyonectria isolates, along with morphological characterisation, enabled the description of 12 species from I. radicicola and four from I. macrodidyma complexes. Among these, pathogenicity experiments r

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Будаєва, І. В., та Г. О. Ревенко. "Hand-foot-and-mouth disease (HFMD) у Дніпропетровському регіоні". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/64722.

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Ентеровірусний везикулярний стоматит з екзантемою (Hand-Foot-and-Mouth Disease (HFMD)) - захворювання, що перебігає з ураженням шкіри кистей і стоп, слизової оболонки порожнини рота. Ентеровіруси мають тропність до нервової та серцево-судинної системи.<br>Clinical and epidemiological particularities of HFMD in children are presented. Considering cardiotropic features enteroviruses ECG and CFK-MB are evaluated in 14 children. Signs of myocarditis are revealed.

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Ramanoon, Siti. "The epidemiology of foot and mouth disease in Malaysia." Thesis, Ramanoon, Siti (2016) The epidemiology of foot and mouth disease in Malaysia. PhD thesis, Murdoch University, 2016. https://researchrepository.murdoch.edu.au/id/eprint/32386/.

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The objectives of the present study were to determine the prevalence of foot and mouth disease (FMD) and the serotypes of foot and mouth disease virus (FMDV) in Malaysia; to describe the temporal and spatial distribution of FMD in Malaysia; to evaluate the risk of the introduction of FMD to Malaysia; to evaluate the effectiveness of mitigation strategies adopted in Malaysia during outbreaks of FMD; and ultimately to give recommendations on FMD control to the Malaysia-Thailand-Myanmar (MTM) Tri-state Commission and Zoning Working Groups. The first documented outbreak of FMD in Peninsular Ma

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Howes, Emma Louise. "Investigating the foot-and-mouth disease virus 3A protein." Thesis, University of St Andrews, 2018. http://hdl.handle.net/10023/15521.

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Foot-and-Mouth Disease Virus (FMDV) is a globally important pathogen responsible for causing Foot-and-Mouth Disease (FMD) in wildlife and domestic livestock species and has significant economic impacts. FMD is difficult to control due to its highly infectious nature, wide diversity of host species and the existence of multiple serotypes; therefore, understanding the processes of FMDV infection and viral RNA replication are key to the development of improved diagnostics and vaccines. This thesis investigates the potential roles of the FMDV 3A non-structural protein using a combination of sub-ge

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O'Connor, Steven Patrick. "The production of foot-and-mouth disease virus-like particles in the plant Nicotiana benthamiana: a potential candidate vaccine for foot-and-mouth disease." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29378.

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Foot and mouth disease virus (FMDV) infects cloven-hoofed animals causing the highly contagious foot and mouth disease. It is spread by contact or through aerosol. The disease is often debilitating for infected animals and can be fatal. Severe measures are taken to contain outbreaks; quarantine and trade restrictions are imposed and herds with infected individuals are culled to prevent the spread of the disease. Consequently, outbreaks of the disease have drastic implications for agriculture and social economies which can be devastating for affected countries. There are seven serotypes of the

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