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Rozprawy doktorskie na temat „Forensic genetics”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Tillmar, Andreas. "Populations and Statistics in Forensic Genetics." Doctoral thesis, Linköpings universitet, Institutionen för klinisk och experimentell medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-54742.

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DNA has become a powerful forensic tool for solving cases such as linking a suspect to a crime scene, resolving biological relationship issues and identifying disaster victims. Traditionally, DNA investigations mainly involve two steps; the establishment of DNA profiles from biological samples and the interpreta-tion of the evidential weight given by theses DNA profiles. This thesis deals with the latter, with focus on models for assessing the weight of evidence and the study of parameters affecting these probability figures. In order to calculate the correct representative weight of DNA evide

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2

Santos, Leonardo Soriano de Mello 1976. "Viabilidade da utilização de amostras biologicas obtidas de dentes humanos para obtenção de perfis geneticos de DNA." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290762.

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Orientadores: Eduardo Daruge Junior, Darcy de Oliveira Tosello<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-12T19:58:07Z (GMT). No. of bitstreams: 1 Santos_LeonardoSorianodeMello_M.pdf: 882529 bytes, checksum: a98503a69a38c35d2491b2e9cd210308 (MD5) Previous issue date: 2009<br>Resumo: Alguns fatores relacionados ao estado e lugares que dentes humanos se encontram, nos que diz respeito a estes enquanto amostras com finalidade forense, ainda constituem desafio ao que tange o uso dos mesmos como mate

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3

Gettings, Katherine Butler. "Forensic Ancestry and Phenotype SNP Analysis and Integration with Established Forensic Markers." Thesis, The George Washington University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3590467.

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<p> When an evidential DNA profile does not match identified suspects or profiles from available databases, further DNA analyses targeted at inferring the possible ancestral origin and phenotypic characteristics of the perpetrator could yield valuable information. Single Nucleotide Polymorphisms (SNPs), the most common form of genetic polymorphisms, have alleles associated with specific populations and/or correlated to physical characteristics. With this research, single base primer extension (SBE) technology was used to develop a 50 SNP assay designed to predict ancestry among the primary U.S

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Nilsson, Martina. "Mitochondrial DNA in Sensitive Forensic Analysis." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7458.

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Andréasson, Hanna. "Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification." Doctoral thesis, Uppsala University, Department of Genetics and Pathology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5775.

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<p>The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented.</p><p>In order to maximise the use of valuable limited DNA samples, a fast and user-friendly Real-time PCR quantification assay, of nuclear and mitochondrial DNA copies, was developed. The system is based on the 5’ exonuclease detection assa

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6

Divne, Anna-Maria. "Evaluation of New Technologies for Forensic DNA Analysis." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5744.

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Reid, Kate Megan. "Forensic human identification: Generating Y-STR data for the South African population." Master's thesis, Faculty of Health Sciences, 2018. http://hdl.handle.net/11427/30060.

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Salt River Mortuary (SRM), Cape Town, investigates ~3500 cases of unnatural death annually, with an apparent burden of unclaimed bodies. A retrospective review was first undertaken to assess the number of these individuals who remained unidentified. Medicolegal records were examined (2010-2017), and ~9% of cases remained unidentified each year. DNA analysis was performed in 23.5% of cases. At the time of this study, unidentified bodies were in storage for up to two years, pending pauper burial. DNA profiling assists forensic human identification, and the analysis of markers on the Y-chromosome

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8

Tully, Gillian. "DNA profiling for forensic identification : evaluation of polymerase chain reaction methods." Thesis, Cardiff University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264882.

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Bashir, Majid. "Application of autosomal INDELs as a forensic tool in Qatar." Thesis, University of Central Lancashire, 2016. http://clok.uclan.ac.uk/15480/.

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Short tandem Repeats (STRs) are the most commonly genetic markers used in forensic human identification. However, in some cases they are not able to yield complete profiles because of DNA degradation and/or inhibition. The STR profiling of the degraded/inhibited DNA samples can result in allelic drop-outs and even no profile at all. Alternatively, single nucleotide polymorphisms (SNPs) can be used to address the issues of DNA degradation and inhibition due to their smaller amplicons. But their use in regular forensic case work is limited due to additional steps (sequencing based) and time cons

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10

Tau, Tiroyamodimo. "A forensic analysis of genetic variation in the Botswana population." University of the Western cape, 2016. http://hdl.handle.net/11394/5657.

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Philosophiae Doctor - PhD<br>This thesis has been placed under a long term embargo. Forensic and population genetic parameters were investigated in the Botswana population using autosomal and Y-chromosome short tandem repeat markers. AmpFlSTR Profiler plus markers were used to investigate the genetic diversity and forensic parameters in 773 individuals from Botswana from the reference database of the Botswana Police. The levels of polymorphism found using the AmpFlSTR Profiler Plus markers showed that the nine loci that make up the AmpFlSTR Profiler Plus can differentiate individuals for foren

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11

Palmour, Nicole. "Forensic applications of molecular genetics: ethics and law to inform policy issues." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66662.

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Molecular analysis of DNA variation has usurped the place of all earlier technologies in forensic identification of victims and suspects alike. Although the field of ethics has made attempts to cope with the plethora of available genetic information, especially in clinical application, there has been little scrutiny of emerging ethical issues in the forensic domain. Legal scholarship highlights some aspects of the emerging issues, with particular relevance to the challenges faced in court and those regarding individual liberties. The overall objective of this thesis was to ev

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12

Ambrosio, Isabela Brunelli [UNESP]. "Análise de SNPs do DNA mitocondrial em indivíduos residentes no estado do Espírito Santo para aplicação na Identificação Humana." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/124408.

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Made available in DSpace on 2015-07-13T12:10:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-23. Added 1 bitstream(s) on 2015-07-13T12:25:39Z : No. of bitstreams: 1 000825088_20160130.pdf: 143158 bytes, checksum: 1209a3e2f1bc3903da54429dc938e213 (MD5) Bitstreams deleted on 2016-02-01T10:15:52Z: 000825088_20160130.pdf,. Added 1 bitstream(s) on 2016-02-01T10:16:43Z : No. of bitstreams: 1 000825088.pdf: 567086 bytes, checksum: 73ca882633cceb536b683b63c338096b (MD5)<br>A identificação humana por meio do DNA constitui um dos produtos mais revolucionários da Genética Moderna, tornand

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Choy, Yan-tsun. "Statistical evaluation of mixed DNA stains." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42664287.

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14

Van, Winkle Carolyn. "Forensic DNA Extraction Strategies for PCR Analysis." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc278269/.

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There is a transition nationwide on the analysis of forensic evidentiary stains containing biological material from traditional serology to Polymerase Chain Reaction (PCR) methodologies. The increased sensitivity of PCR, the limited number of alleles at each locus, and the necessity of producing unambiguous data for entry into the FBI's Combined DNA Index System make this study of extraction procedures of utmost importance. A "single tube" extraction procedure for blood stains collected onto FTA™ paper and a modified differential nonorganic extraction method from spermatozoa containing mixed

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15

Edlund, Hanna. "Sensitive Identification Tools in Forensic DNA Analysis." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131904.

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DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. In Paper I and II, two novel systems for analysis of STRs, based on the Pyrosequencing technology, are presented. In Paper I, Y chromosomal STRs are analysed. Markers on the male specific Y chromosome are especially useful in analysis of DNA mixtures. In Paper II, ten autosomal STRs are genotyped. T

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16

Hu, Yueqing. "Some topics in the statistical analysis of forensic DNA and genetic family data." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38831491.

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Wheate, Rhonda Marie Physical Environmental &amp Mathematical Sciences Australian Defence Force Academy UNSW. "Jury comprehension and use of forensic science." Awarded by:University of New South Wales - Australian Defence Force Academy. School of Physical, Environmental and Mathematical Sciences, 2007. http://handle.unsw.edu.au/1959.4/38644.

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The ability of jurors and juries to comprehend and utilise scientific evidence in Australian criminal trials has been examined. From mock jury surveys relating to DNA profiling evidence, it was determined that most respondents were able to comprehend some basic and applied statistics, although their ability was in part related to their knowledge of English and their level of education. The point at which mock jurors were prepared to convict an accused solely on the basis of DNA profiling evidence was examined and found to be low compared with the strength of DNA profiling evidence commonly pre

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18

Smith, Tiffany Lynn. "Investigating the potential of RNA to be used in forensic casework analysis." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/11018.

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Thesis (M.S.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains vi, 60 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 58-60).

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19

Choy, Yan-tsun, and 蔡恩浚. "Statistical evaluation of mixed DNA stains." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42664287.

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20

Stefaniw-Alvarez, Michelle. "Physical characteristics of an individual the identification of biomarkers for biological age determination /." Orlando, Fla. : University of Central Florida, 2007. http://purl.fcla.edu/fcla/etd/CFE0001737.

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21

Jackson, Carrie Beth. "A more sensitive sex determination assay." Diss., Connect to online resource - MSU authorized users, 2006.

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22

Derksen, Linda Anne. "Agency and structure in the history of DNA profiling : the stabilization and standardization of a new technology /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 2003. http://wwwlib.umi.com/cr/ucsd/fullcit?p3083460.

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23

Gregonis, Daniel John. "The analysis of twelve forensic DNA genetic markers for Hardy-Weinberg and gametic phase disequilibrium for a Caucasian data base." CSUSB ScholarWorks, 1997. https://scholarworks.lib.csusb.edu/etd-project/1549.

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Jeffery, Kathryn. "Application to forensic genetics to the population biology of western lowland gorillas at LopeÌ, Gabon." Thesis, Cardiff University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408771.

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25

Counsil, Tyler I. "Real-time RNA-based amplification allows for sensitive forensic blood evidence analysis." Virtual Press, 2008. http://liblink.bsu.edu/uhtbin/catkey/1391475.

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The purpose of this experiment was to determine if nucleic acid sequence based amplification (NASBA) is a suitable application for the differentiation of body fluids that might comprise a forensic evidence sample. NASBA is a sensitive RNA transcription based amplification system. NASBA could theorhetically be used for bodily fluid identification based upon amplification of tissue-specific mRNA transcripts present in a given forensic sample.Amplification of both Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and Matrix Metalloproteinase 1 1 (MMPmRNA transcripts were used to determine that NAS

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Hu, Yueqing, and 胡躍清. "Some topics in the statistical analysis of forensic DNA and genetic family data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38831491.

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Kemp, Philip M. (Philip Marcus). "A Forensic Marker for a Genetic Disease Often Misdiagnosed as Sudden Infant Death Syndrome (SIDS)." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc500567/.

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Sudden Infant Death (SIDS) has been associated with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid oxidation. Blood and tissue samples from a large cohort of SIDS victims were analyzed for the presence of dodecanoic acid (C₁₂) by gas chromatography. A subgroup of these cases had a significantly higher blood concentration than age-matched controls, suggesting MCAD deficiency. An animal study using Sprague-Dawley rats was done to mimic the effects of MCAD deficiency. Significantly increased blood concentrations of dodecanoic acid were observed. Decreased val

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28

OLIVEIRA, Tatiana Costa de. "DNA humano extraído a partir de larvas de dípteros coletadas em cadáveres no instituto médico legal de Pernambuco." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/17461.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-07-19T13:40:55Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) tese final.pdf: 4052323 bytes, checksum: 74297c119131b87a26908be1d213027a (MD5)<br>Made available in DSpace on 2016-07-19T13:40:55Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) tese final.pdf: 4052323 bytes, checksum: 74297c119131b87a26908be1d213027a (MD5) Previous issue date: 2015-12-01<br>CAPEs<br>O uso de insetos visando responder aos quesitos leva

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Duz, Lana Maximiliano. "Evolução tecnologica dos exames de paternidade e sua validade juridica." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290723.

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Orientador: Eduardo Daruge<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-08T13:00:49Z (GMT). No. of bitstreams: 1 Duz_LanaMaximiliano_M.pdf: 1631832 bytes, checksum: 21f1803209411391e4eeb5b87478e6ae (MD5) Previous issue date: 2007<br>Resumo: A ciência e a tecnologia vêm se sobrepujando constantemente e seus avanços repercutem nas deliberações do Poder Judiciário. Decisões sobre paternidade baseadas em técnicas, atualmente suplantadas pelo avanço da ciência, têm sido questionadas judicialmente, colo

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Ambrosio, Isabela Brunelli. "Análise de SNPs do DNA mitocondrial em indivíduos residentes no estado do Espírito Santo para aplicação na Identificação Humana /." Araraquara, 2015. http://hdl.handle.net/11449/124408.

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Orientador: Regina Maria Barretto Cicarelli<br>Banca: Joyce Aparecida Martins Lopes Ferraz<br>Banca: Rogério Nogueira de Oliveira<br>Resumo: A identificação humana por meio do DNA constitui um dos produtos mais revolucionários da Genética Moderna, tornando-se uma ferramenta indispensável na investigação criminal. Essa identificação é baseada no perfil genético do indivíduo, pela combinação de diversos marcadores herdados de seus progenitores. Os marcadores são, geralmente,e diferenças nas sequências de DNA nuclear entre os indivíduos (polimorfismos). Em alguns casos, em que a análise do DNA nu

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31

Barlow, Vicki. "The development of enhanced experimental strategies for the DNA analysis of low-template or compromised forensic sample types." Thesis, Northumbria University, 2015. http://nrl.northumbria.ac.uk/30231/.

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Single-cell DNA analysis is not routinely carried out in a forensic setting as it is considered unreliable due to challenges associated with DNA amplification, contamination and profile interpretation. In light of the development of increasingly sensitive techniques, the question of the reliability of single-cell DNA analysis in terms of both processing and interpretation is addressed in the first part of this thesis. Optimising all stages of the DNA analysis process has provided a sensitive method which facilitates the successful outcome of a useable profile from single-cells. Although no con

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Graversen, Therese. "Statistical and computational methodology for the analysis of forensic DNA mixtures with artefacts." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:4c3bfc88-25e7-4c5b-968f-10a35f5b82b0.

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This thesis proposes and discusses a statistical model for interpreting forensic DNA mixtures. We develop methods for estimation of model parameters and assessing the uncertainty of the estimated quantities. Further, we discuss how to interpret the mixture in terms of predicting the set of contributors. We emphasise the importance of challenging any interpretation of a particular mixture, and for this purpose we develop a set of diagnostic tools that can be used in assessing the adequacy of the model to the data at hand as well as in a systematic validation of the model on experimental data. A

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33

Ara, Andleeb. "Development of NASBA-primer search software for designing forensic saliva tandem repeat markers for mucin and amylase." Muncie, Ind. : Ball State University, 2009. http://cardinalscholar.bsu.edu/635.

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Valenzuela, Robert Keams. "Predictive Modeling for Complex Traits: Normal Human Pigmentation Variation." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/145309.

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Melanin pigmentation is a complex trait governed by many genes. Variation in melanin pigmentation within, and between, populations makes it an important trait for assisting in physical identification of an individual in forensic investigations. Utilizing a training sample (n=789) comprised of various ethnicities and SNPs (75) in 24 genes previously implicated in human or animal pigmentation studies, I determined three-SNP multiple linear regression models that accounted for large proportions of pigmentation variation in skin (45.7%), eye color (76.4%), and hair [eumelanin-to-pheomelanin (43.

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Schlaphoff, Theresa Elizabeth-Anne. "A study to evaluate variable number of tandem repeat DNA polymorphisms in disputed paternity testing." Thesis, Cape Technikon, 1993. http://hdl.handle.net/20.500.11838/1465.

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Thesis (MDip (Medical Technology))--Cape Technikon, 1993<br>The use of genetic marker testing to resolve cases of disputed paternity, is well established. The number and range of systems used depends on the expertise of the laboratory, and for this reason various laboratories offer different systems. Standard testing includes tests in the following genetic marker systems: human leukocyte antigen (tissue) typing; red cell blood groups; and red cell enzyme and serum protein testing. The Provincial Laboratory for Tissue Immunology currently offers a range of 16 genetic marker systems cap

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Chung, Denise T. "The development of novel STR miniplex primer sets for the analysis of degraded and compromised DNA samples." Ohio : Ohio University, 2004. http://www.ohiolink.edu/etd/view.cgi?ohiou1097609199.

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Jacobs, Gwynneth. "Evaluation of insertion-deletion polymorphisms with the kit Qiagen Investigator® DIPplex for forensic application in South Africa." University of the Western Cape, 2015. http://hdl.handle.net/11394/4690.

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>Magister Scientiae - MSc<br>Insertion-deletion polymorphisms (indels) have been underutilized in forensic identification of individuals in comparison with single nucleotide polymorphisms (SNPs) and short tandem repeat (STRs) systems. The use of indels for the purpose of human identification is more advantageous than previously used methods as it combines desirable characteristics of both the SNPs and STRs i.e. low costs and simplistic typing methods as well as indels having small amplicons size, making them suitable for genotyping highly degraded DNA. Currently there is only one commer

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Warren, Joseph E. "Mutation Rate Analysis of the Human Mitochondrial D-loop and its Implications for Forensic Identity Testing." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2492/.

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To further facilitate mitochondrial DNA (mtDNA) sequence analysis for human identity testing, a better understanding of its mutation rate is needed. Prior to the middle 1990's the mutation rate applied to a forensic or evolutionary analysis was determined by phylogenetic means, This method involved calculating genetic distances as determined by amino acid or DNA sequence variability within or between species. The mutation rate as determined by this method ranged from 0.025-0.26 nucleotide substitutions/ site/ myr (million years). With the recent advent of mtDNA analysis as a tool in human iden

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39

Ehrenreich, Liezle Suzette. "The evaluation of Y-STR loci for use in forensics." Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9766_1228396041.

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<p>The aim of this study was to investigate the forensic usefulness of various Y-chromosome short tandem repeat loci among South African sub-populations. Three different sets of Y-chromosome short tandem repeat loci were chosen for investigation.</p>

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Groß, Theresa Elisa [Verfasser]. "Development of novel SNP panels for the application of massively parallel sequencing to forensic genetics / Theresa Elisa Groß." Köln : Deutsche Zentralbibliothek für Medizin, 2017. http://d-nb.info/1144184878/34.

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Candido, Ian Marques. "COMPARAÇÃO ENTRE AS TÉCNICAS DE EXTRAÇÃO DE DNA EM OSSO HUMANO POR PARTÍCULAS MAGNÉTICAS E COLUNA DE SÍLICA." Pontifícia Universidade Católica de Goiás, 2013. http://localhost:8080/tede/handle/tede/2359.

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Made available in DSpace on 2016-08-10T10:38:39Z (GMT). No. of bitstreams: 1 Ian Marques Candido.pdf: 1079357 bytes, checksum: dac0a34c413d6875a597e0f2ba2a41f6 (MD5) Previous issue date: 2013-02-08<br>The identification of human remains in decomposition, charred, skeletal remains and mass disasters can be performed by Forensic Genetics and, in most cases, bones and teeth are the only viable source for DNA typing .Thus, considering the large number of bones used in human identification and the need for standardization of DNA extraction in this kind of sample, the aim of this study is to compa

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42

Wagner, Sarah Jean. "Efficiency of DNA Recovery from Different Swab Types by qPCR." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1616962034143618.

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SIMÔES, DUTRA CORREA HEITOR. "ASSESSING THE USEFULNESS OF RAMAN SPECTROSCOPY AND LIPID ANALYSIS OF DECOMPOSED HUMAN BONES IN FORENSIC GENETICS AND MOLECULAR TAPHONOMY STUDIES." Doctoral thesis, Università degli studi di Brescia, 2022. http://hdl.handle.net/11379/559020.

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Forensic DNA testing is the application of genetic analyses to help elucidate legal disputes. DNA analyses can be performed not only on biological samples from living persons, but also from deceased individuals or their decomposed remains. Such analyses have been extremely valuable to society, allowing the formal identification of countless missing persons and unidentified human remains. In practice, mineralized organs, such as bones, are among the structures most likely to be recovered after death. Decomposition is a complex process that leads to transformation and degradation of all molecule

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SIMÔES, DUTRA CORREA HEITOR. "ASSESSING THE USEFULNESS OF RAMAN SPECTROSCOPY AND LIPID ANALYSIS OF DECOMPOSED HUMAN BONES IN FORENSIC GENETICS AND MOLECULAR TAPHONOMY STUDIES." Doctoral thesis, Università degli studi di Brescia, 2022. http://hdl.handle.net/11379/559017.

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Forensic DNA testing is the application of genetic analyses to help elucidate legal disputes. DNA analyses can be performed not only on biological samples from living persons, but also from deceased individuals or their decomposed remains. Such analyses have been extremely valuable to society, allowing the formal identification of countless missing persons and unidentified human remains. In practice, mineralized organs, such as bones, are among the structures most likely to be recovered after death. Decomposition is a complex process that leads to transformation and degradation of all molecule

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SIMÔES, DUTRA CORREA HEITOR. "ASSESSING THE USEFULNESS OF RAMAN SPECTROSCOPY AND LIPID ANALYSIS OF DECOMPOSED HUMAN BONES IN FORENSIC GENETICS AND MOLECULAR TAPHONOMY STUDIES." Doctoral thesis, Università degli studi di Brescia, 2022. http://hdl.handle.net/11379/559015.

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Forensic DNA testing is the application of genetic analyses to help elucidate legal disputes. DNA analyses can be performed not only on biological samples from living persons, but also from deceased individuals or their decomposed remains. Such analyses have been extremely valuable to society, allowing the formal identification of countless missing persons and unidentified human remains. In practice, mineralized organs, such as bones, are among the structures most likely to be recovered after death. Decomposition is a complex process that leads to transformation and degradation of all molecule

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Khoory, Haifa. "The feasibility of transferring cells from archived buccal swabs to FTA card for long term and simple storage of forensic samples." University of Western Australia. Centre for Forensic Science, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0088.

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[Truncated abstract] The collection of buccal cells is common practise in the epidemiological and forensic science. Unlike venipuncture collection of blood; it is a safer, non-invasive method for collection of biological material. The methods by which these cells are collected from the inner cheek of an individual and stored are the key elements in preserving DNA. Typically, forensic samples require long term storage. Samples are commonly collected on cotton swabs and stored moist at low to ultra-low temperatures (less than -20oC). Although this is the method of choice in most forensic facilit

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Pitt, Alison Patricia. "Comparison of Middle Eastern Bedouin genotypes with previously studies populations using polymorphic Alu insertions." University of Western Australia. Centre for Forensic Science, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0119.

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[Truncated abstract] Polymorphic Alu insertions (POALINs) are known to contribute to the variation and genetic diversity of the human genome. In this report specific POALINs of the Major Histocompatibility Complex (MHC) were studied. Previous population studies on the MHC POALINs have focused on individuals of African, European and Asian descent. In this study, we expand the research by studying a new and previously uncharacterised population, focusing on the Bedouin from the Middle East. Specifically we report on the individual insertion frequencies of four POALINs within the MHC class I regi

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Sánchez-Molero, Núñez Olallo-Efrén. "Muerte súbita natural inexplicada: valor de la investigación genética post mortem." Doctoral thesis, Universitat de Girona, 2017. http://hdl.handle.net/10803/666973.

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Natural death defines the death primarily attributed to an illness or an internal malfunction of the body, and not directly influenced by external forces. Most causes can be identified directly with macroscopic forensic analysis. However, when a macroscopic cause is not evident, the final identification of causality can become tedious and complicated. This study therefore demonstrates that identification of such genetic alterations may help to identify the etiology and also the underlying cause in such deaths Finally identification of genetic variations enables genetic counselling and undertak

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Dušan, Vapa. "Varijabilnost mikrosatelitskih lokusa X hromozoma u populaciji Vojvodine." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2016. https://www.cris.uns.ac.rs/record.jsf?recordId=95598&source=NDLTD&language=en.

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Kratki uzastopni ponovci predstavljaju klasu mikrosatelitskih segmenata DNK, rasprostranjenih &scaron;irom genoma čoveka. Građeni su od uzastopno ponavljajućih sekvenci dužine 2-6 parova nukleotida. Zahvaljujući različitom broju ponavljanja repetitivne jedinice, većina mikrosatelitskih markera pokazuje visok stepen polimorfizma dužine, koji je moguće ispitati primenom tehnike lančane reakcije polimeraze. Pored utvrđivanja spornih srodničkih odnosa, analiza X hromozom mikrosatelitskih markera može se uspe&scaron;no koristiti i u oblastima kriminalistike, humane identifikacije, populaciono-genet

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Kasu, Mohaimin. "Validation and application of a highly discriminating and rapid 10-locus Y-STR DNA profiling system." University of the Western Cape, 2019. http://hdl.handle.net/11394/6760.

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Philosophiae Doctor - PhD<br>DNA profiling the male specific region on the Y-chromosome is fundamental to forensic practise. Its recognised as a powerful analytical tool for investigation of sexual assault when the DNA evidence is highly admixed. Standard practises for processing sexual assault evidence include physically separate the sperm cell from the female fraction using differential extraction followed by autosomal DNA profiling. However, under specific scenarios of assault physical separation may not be possible due to the nature of the evidence. The research presented in this thesis w

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