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1

Schubert, Clara-Lynn, Barbara Ryckewaert, Carlos Pereira, and Tetsuro Matsuzawa. "Garrano Horses Perceive Letters of the Alphabet on A Touchscreen System: A Pilot Study." Animals 12, no. 24 (2022): 3514. http://dx.doi.org/10.3390/ani12243514.

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This study aimed to use a computer-controlled touchscreen system to examine visual discrimination in Garrano horses (Equus caballus), an endangered breed of pony belonging to the Iberian horse family. This pilot study focused on the perceptual similarity among letters of the alphabet. We tested five horses in a one-male unit (OMU) living permanently in a semi-free enclosure near their natural habitat in Serra d’Arga, northern Portugal. Horses were trained to nose-touch black circles that appeared on the screen. Then, they were tested for discrimination of five letters of the Latin alphabet in
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Pere, M. Parés-Casanova. "Does Caballine Fold Define Caballines?" Journal of Applied Life Sciences International 12, no. 1 (2017): 1–4. https://doi.org/10.9734/JALSI/2017/33685.

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A sample of 35 upper cheek series belonging to <em>Garrano</em> (n=30) and <em>Galego</em> (n=5) specimens were studied in order to describe pli caballin (caballine fold). Occlusal aspects presented much cement and they were moderately complex, and pli was absent in more than half of studied M<sup>1</sup> and M<sup>2</sup> (56.5% and 57.9% respectively). Moreover, most, but not all premolars presented pli (80.8%, 77.8% and 67.9% for pM<sup>1</sup>, pM<sup>2</sup>, pM<sup>3</sup> respectively). So, the presence of pli caballin is not an absolute descriptor of <em>Equus caballus</em> for isolate
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Yang, Sheng-lin, Ai-Ping Li, Long-xing Xu, and Haibing Yang. "Short Communication: Mitochondrial DNA D-loop sequence diversity and origin of Chinese pony breeds (Equus caballus)." Canadian Journal of Animal Science 93, no. 3 (2013): 313–19. http://dx.doi.org/10.4141/cjas2012-160.

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Yang, S.-l., Li, A.-P., Xu, L.-x. and Yang, H. 2013. Short Communication: Mitochondrial DNA D-loop sequence diversity and origin of Chinese pony breeds ( Equus caballus ). Can. J. Anim. Sci. 93: 313–319. Previous studies based on mitochondrial DNA (mtDNA) data have shown that Chinese horses have high genetic diversity. However, little is known about the genetic diversity of mtDNA D-loop sequences and maternal origin of five Chinese pony breeds. In the present study, genetic diversity of 343-bp D-loop sequences for136 individuals representing five Chinese pony breeds was analyzed. To address th
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Emilio Katsoulakou, Myrina, Nikolaos Kostaras, H. Josefina Kjöllerström, et al. "Indigenous Greek Horse Breeds: Genetic Structure and the Influence of Foreign Breeds." Agriculture 15, no. 5 (2025): 540. https://doi.org/10.3390/agriculture15050540.

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This study aims to examine the genetic structure and diversity levels of seven indigenous Greek horse breeds: Andravida, Pindos, Thessaly, Skyros, Penia, Messara and Rodos, using 15 microsatellites. Phenotypic traits were combined with factorial correspondence analyses to create two datasets: one “Baseline” containing typical samples, and one “Unknown” with non-typical or of disputed origin samples. In the Greek “Baseline” horses, 142 alleles were found. The mean observed and effective number of alleles, the polymorphism information content and the allelic richness were 6.75, 4.14, 0.63 and 5.
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Garrido, Susana, Alberto G. Murta, Ana Moreira, Maria João Ferreira, and Maria Manuel Angélico. "Horse mackerel (Trachurus trachurus) stomach fullness off Portugal: index calibration and spatio-temporal variations in feeding intensity." ICES Journal of Marine Science 65, no. 9 (2008): 1662–69. http://dx.doi.org/10.1093/icesjms/fsn169.

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Abstract Garrido, S., Murta, A. G., Moreira, A., Ferreira, M. J., and Angélico, M. M. 2008. Horse mackerel (Trachurus trachurus) stomach fullness off Portugal: index calibration and spatio-temporal variations in feeding intensity. – ICES Journal of Marine Science, 65: 1662–1669. An index for stomach fullness used in the routine biological sampling of horse mackerel from Portuguese waters was calibrated about the correspondent stomach mass. The fullness scale comprises four levels (1, empty; 2, &lt;50% filled; 3, &gt;50% filled; 4, bursting) that are easily attributed to whole stomachs during t
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Barradas, Patrícia F., João Marques, Catarina Tavares, Nuno Vieira Brito, and João R. Mesquita. "Detection of tick-borne pathogens in Rhipicephalus bursa ticks collected from the autochthonous Garrano breed of horses in Portugal." Veterinary Parasitology: Regional Studies and Reports 51 (June 2024): 101033. http://dx.doi.org/10.1016/j.vprsr.2024.101033.

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Al-Jamrah, Khaled Mohammed, Abdulkareem Nassar, Ibrahim Mohathab, and Mohammed Al Amad. "Dengue Fever Outbreak in Al-Garrahi District, Al-Hudaydah Governorate, Yemen, 2019." Iproceedings 8, no. 1 (2022): e36466. http://dx.doi.org/10.2196/36466.

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Background Dengue fever (DF) has re-emerged in Yemen with a higher frequency during the last years. On November 6, 2019, an increased number of suspected DF cases in Al-Garrahi district was reported. On November 7, 2019, a team was sent to investigate. Objective This study aims to confirm the existence of an outbreak, describe the outbreak characteristics, and recommend suitable intervention for control. Methods A descriptive study was conducted. The World Health Organization case definition was used to identify patients. An active search from house to house, along with entomological investiga
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Garrido, Javiera, Evelin González, Alejandro Blanco, et al. "Abstract 1005: Germline-somatic interactions in non-small cell lung cancer (NSCLC) patients from Latin America." Cancer Research 85, no. 8_Supplement_1 (2025): 1005. https://doi.org/10.1158/1538-7445.am2025-1005.

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Abstract Motivation: Tumors of non-small cell lung cancer (NSCLC) patients are heterogeneous entities. Genomic landscapes are influenced by genetic constitution, environmental exposures and the complex interaction between the two. In particular, it has been reported that germline variability specific to Latin American (LA) populations play an important role modulating the presence of acquired somatic alterations in EGFR and KRAS, two of the most clinically relevant actionable genes for lung cancer (LC). The influence of these specific genetic differences appears to be independent of smoking st
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Singh, Rajesh K., Rameshwari Rayaji, Bindi Patel, et al. "Abstract 1367: HPK1 inhibition enhances T cell activation and relieves the immunosuppressive phenotype of inhibitory signals found in the tumor microenvironment." Cancer Research 82, no. 12_Supplement (2022): 1367. http://dx.doi.org/10.1158/1538-7445.am2022-1367.

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Abstract Introduction: T cell activation is critical in the initiation and potentiation of anti-tumor immune responses. Hematopoietic Progenitor Kinase 1 (HPK1/MAP4K1) is a member of the MAP4K family whose activity has been demonstrated to restrain T cell activation through phosphorylation of SLP-76 at Serine 376 leading to TCR disassembly. Mediators generated in the tumor microenvironment (TME) such as adenosine, PGE2 and TGFβ can dampen T cell activity and present a significant barrier to cancer therapy. HPK1 inhibition may allow for enhanced T cell activation under such suppressive conditio
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10

Rahman, P., M. Garrido-Cumbrera, S. Rohekar, et al. "SAT0638-HPR CHARACTERIZING THE IMPACT OF AXIAL SPONDYLOARTHRITIS ON DAILY LIFE: GENDER AND PATIENT-REPORTED OUTCOMES ASSOCIATED WITH FUNCTIONAL LIMITATION IN CANADA. RESULTS FROM THE IMAS SURVEY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1278.2–1279. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4574.

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Background:Understanding the most limiting daily activities reported by patients is important for a holistic healthcare approach.Objectives:To evaluate the degree of functional limitation on daily activities and its association with PROs in Canada.Methods:The International Map of Axial Spondyloarthritis (IMAS) is a cross-sectional online survey of non-selected patients with self-reported axSpA conducted in 22 countries and endorsed by the Axial Spondyloarthritis International Federation. IMAS captures the patients’ perspective of the burden of axSpA. The Canadian adaptation included a review o
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11

KAWAI-KAWACHI, Asuka, Madison LENORMAND, Clémence HENON, et al. "Abstract 6277: Identification of ATR inhibitors as therapeutic opportunities in Desmoplastic small round cell tumors." Cancer Research 82, no. 12_Supplement (2022): 6277. http://dx.doi.org/10.1158/1538-7445.am2022-6277.

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Abstract Introduction: Desmoplastic small round cell tumor (DSRCT) is a rare and very aggressive subtype of sarcoma, affecting predominantly young males. DSRCT is molecularly characterized by the t(11;22)(q24;q12) chromosomal translocation, which fuses EWSR1 to WT1 and encodes an aberrant chimeric transcription factor. A few additional secondary mutations have been reported, notably in genes encoding proteins involved in chromatin remodeling and DNA repair. No therapeutic advance have been done in the past 20 years, and the five-year overall survival is still below 15% in metastatic cases, des
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12

Henon, Clémence, Julien Vibert, Thomas Eychenne, et al. "Abstract 6932: Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in desmoplastic small round cell tumors." Cancer Research 84, no. 6_Supplement (2024): 6932. http://dx.doi.org/10.1158/1538-7445.am2024-6932.

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Abstract Background: Desmoplastic Small Round Cell Tumor (DSRCT) is a rare, aggressive sarcoma primarily affecting young males. Despite being driven by the unique oncogenic transcription factor (TF) EWSR1-WT1, and a monotonous morphology, DSRCT cells display a polyphenotypic differentiation of unknown etiology. Methods: To explore DSRCT heterogeneity, we characterized a series of patient samples by single-cell, spatial, and bulk multi-omics. We integrated patients’ data with bulk RNA-sequencing, ChIP-sequencing, and ATAC-sequencing data generated in a DSRCT cell line model upon EWSR1-WT1 trans
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13

Gruber, Andrea, Sven Christian, Carsten Schmeck, et al. "Abstract 4348: A translational pharmacokinetic-pharmacodynamic (PKPD) modeling framework of novel, highly selective, next-generation allosteric cyclin-dependent kinase 2 (CDK2) inhibitors." Cancer Research 85, no. 8_Supplement_1 (2025): 4348. https://doi.org/10.1158/1538-7445.am2025-4348.

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Abstract Background: CDK2 plays a crucial role in regulating multiple oncogenic signaling pathways, and its activity is essential for the loss of growth control during cancer development. The amplification and overexpression of the CDK2 binding partner Cyclin E1 (CCNE1) is a key mechanism in various cancers. Selective CDK2/CCNE1 inhibition therefore offers a promising treatment for patients with CCNE1 overexpressing tumors. CDK2/CCNE1 inhibition has been shown to reduce phosphorylation of the retinoblastoma protein (pRB), a direct downstream target, which is associated with decreased tumor gro
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14

Garrido-Cumbrera, M., V. Navarro-Compán, C. Bundy, et al. "SAT0374 ONSET OF AXIAL SPONDYLOARTHRITIS REPERCUSSIONS ON PATIENTS’ SOCIAL AND FAMILY LIFE: RESULTS FROM THE EUROPEAN MAP OF AXIAL SPONDYLOARTHRITIS (EMAS)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1134.2–1135. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4293.

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Background:Axial Spondyloarthritis (axSpA) is associated with a high degree of functional limitation in daily life activities. However, few studies have evaluated the social and family burden from the patient’s perspective.Objectives:To describe the impact of axSpA on social and family life since disease onset, and the associated PROs.Methods:Data from 2,846 unselected patients of the European Map of Axial Spondyloarthritis (EMAS) study through an online survey (2017-2018) across 13 European countries were analysed. The impact of axSpA on social and family life were assessed through four PROs:
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Povoli, A., S. Grubissa, L. Molino, M. Marino, and D. Berretti. "N43 the "help-line telephone" form: a new telemedical support for managing patients with ibd." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i2507. https://doi.org/10.1093/ecco-jcc/jjae190.1575.

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Abstract Background In the current healthcare economy, the implementation of telemedicine is rapidly evolving.The rationale for development and advancement in this area seems to be dual: first, to improve speed and efficiency in the supply of health counseling and decision making, and second, to provide access to patients in rural areas.IBD has a significant medical, social and financial impact considering the constant increasing worldwide in its incidence and prevalence.Our study aims to determine how much the "Help-line telephone" form that supports phone call could become a useful tool to t
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Mendonça, Renata S., Pandora Pinto, Tamao Maeda, et al. "Population Characteristics of Feral Horses Impacted by Anthropogenic Factors and Their Management Implications." Frontiers in Ecology and Evolution 10 (June 22, 2022). http://dx.doi.org/10.3389/fevo.2022.848741.

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Feral horses form relatively stable harems over time that are characterized by long-lasting bonds among their members, a characteristic that makes them an exceptional case of a social system among terrestrial ungulates. Their social system has been described as uniform despite the wide differences in their environment and demography. Horse populations subjected to human interference often show higher levels of population instability that can ultimately compromise their reproductive success. In this article, we describe demographic and dynamic changes of a Portuguese population of Garranos in S
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Abedini, W. I., G. R. Ciocchini, and R. M. Marlats. "Results in the clonation of Melia Azederach L. and M. toosendan Sieb. et Zucc. resistant to the cold." Forest Systems, December 1, 1991, 143–49. http://dx.doi.org/10.5424/1301.

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The variability observed in the results of the descendants of the selected specimens by resistance to the cold of Melia azederach and Melia toosendan may surpass through the vegetative propagations of the selected trees. In the Experimental Farmland of the Faculty of Agronomy of the National University of La Plata situated to the 34º55' LS; 57º57' LW 15 m s.n.m. Province of Buenos Aires - Argentine Republic, selections of Melia azederach and Melia toosendan cultures selections were made which survived to low temperatures. The used method for the vegetative propagation consisted on the immersio
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18

Ruiz, Jiménez Juan. "Miserere en el Campo Santo de los Mártires de Córdoba (1633)." Paisajes sonoros históricos (c.1200-c.1800), December 16, 2023. https://doi.org/10.5281/zenodo.10394865.

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El 3 de marzo de 1633, el cabildo de la catedral de Córdoba prohíbe el <em>Miserere</em> que se cantaba por las noches en el Campo Santo de los Mártires de esta ciudad, sin que sepamos si este decreto llegó a hacerse efectivo. On 3 March 1633, the Chapter of Cordoba Cathedral banned the <em>Miserere</em> that was sung at night in the Campo Santo de los Mártires in Cordoba, although we do not know if this decree was ever enforced.
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Lucero-Orillaza, Hanna E. "Teledermatology: The New Normal?" Acta Medica Philippina 55, no. 5 (2021). http://dx.doi.org/10.47895/amp.v55i5.4024.

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Modern-day telemedicine could find its roots in the handwritten letters sent back and forth from patient to physician in the eighteenth and nineteenth centuries.1 In the recent decades, growth in the practice of telemedicine has been fueled by rapid advances in the field of information and communication technology.2 The arrival of the COVID-19 pandemic only served to accelerate its development and utilization. With social distancing guidelines in place and community quarantine being strictly implemented, people found themselves with limited access to hospitals and clinics. Thus, many physician
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Starrs, Bruno. "Writing Indigenous Vampires: Aboriginal Gothic or Aboriginal Fantastic?" M/C Journal 17, no. 4 (2014). http://dx.doi.org/10.5204/mcj.834.

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The usual postmodern suspicions about diligently deciphering authorial intent or stridently seeking fixed meaning/s and/or binary distinctions in an artistic work aside, this self-indulgent essay pushes the boundaries regarding normative academic research, for it focusses on my own (minimally celebrated) published creative writing’s status as a literary innovation. Dedicated to illuminating some of the less common denominators at play in Australian horror, my paper recalls the creative writing process involved when I set upon the (arrogant?) goal of creating a new genre of creative writing: th
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