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Rozprawy doktorskie na temat „Gastrointestinal”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

White, J. S. "Models of intestinal barrier function and their application in the study of biliary obstruction." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368529.

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2

Vianna, Karina Costa Maia. "Tumor estomal gastrointestinal (GIST)." reponame:Repositório Institucional da UFPR, 2012. http://hdl.handle.net/1884/26630.

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Resumo: Introdução: Os tumores estromais gastrointestinais (GIST) são neoplasias raras que se originam das células intersticiais de Cajal .A última década foi de grande avanço com o esclarecimento dos mecanismos moleculares, seguido da terapia molecular, que propiciaram um grande aumento na sobrevida. Objetivo: Avaliar a experiência do Hospital de Clínicas de Curitiba no tratamento do GIST localizado e avançado, com análise das características clínicas e anatomo-patológicas e uso do imatinibe. Metodologia: Estudo retrospectivo de 32 pacientes com diagnóstico de GIST por imunohistoquímica, c-Ki

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3

Thoree, Cheetranjan Vinay. "Characterisation of gastrointestinal microparticles." Thesis, King's College London (University of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555927.

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Intestinal Peyer's patches, through their specialized M cell-rich epithelium, can act as a portal of entry for bacteria, viruses, macromolecules and particles. Particles can be further classified as exogenous particles such as those derived from the diet in the form of food additives or endogenous particles which result from calcium and phosphate precipitation in the mid-distal intestinal lumen. Although exogenous dietary particles have been found to accumulate in "pigment cells" at the base of the human Peyer's patch, little is known about calcium phosphate particles. This thesis aimed (i) to

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4

Ullah, Sana. "Factors governing gastrointestinal motility." Thesis, University of Hull, 2012. http://hydra.hull.ac.uk/resources/hull:7166.

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Introduction: The reasons for the rapid resolution of diabetes (DM) following bariatric surgery in a significant proportion of patients with morbid obesity remain unclear. This thesis investigates the putative role of changes in gastrointestinal (GI) motility and GI hormones as well as the possible significance of alterations in energy expenditure that occur as a consequence of weight loss. Methodology: My preliminary studies involved a systematic review of GI motility in obesity, and retrospective studies measuring GI motility with alternative methods including capsule endoscopy and hydrogen

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5

Silva, Vera Lisa Generosa da. "Estase gastrointestinal no coelho." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2012. http://hdl.handle.net/10400.5/4935.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Actualmente, como o coelho é um animal de estimação frequente, é importante que o Médico Veterinário esteja bem informado sobre este paciente "exótico", para que assim o consiga acompanhar devidamente. Uma das urgências mais comum neste animal, é a estase gastrointestinal (GI), que é uma doença adquirida, em que ocorre uma diminuição ou interrupção da motilidade do tracto GI. É dos problemas mais desafiantes com que o veterinário poderá ser confrontado, sendo o seu tratamento complexo e a resposta terapêutica do paciente, lenta

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6

Шевченко, Володимир Порфирович, Владимир Порфирьевич Шевченко, Volodymyr Porfyrovych Shevchenko, Z. Jawad, and O. Amazu. "Nsaid - related gastrointestinal bleeding." Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/4899.

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7

Kabke, Geórgia Brum. "Escore prognostico de avaliação nutricional em pacientes com tumores do trato gastrointestinal superior." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/110236.

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8

Tekkis, Paris Procopiou. "Risk-adjustment in gastrointestinal surgery." Thesis, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406906.

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9

Stevenson, Diane J. "P2X7, inflammation and gastrointestinal disease." Thesis, University of Nottingham, 2008. http://eprints.nottingham.ac.uk/28897/.

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The inflammatory bowel diseases, ulcerative colitis and Crohn's disease are characterised by spontaneously relapsing and remitting inflammation, associated with increased mucosal levels of the inflammatory cytokine, interleukin-1 (IL-1)β. IL-1β processing and release is mediated by ATP stimulation of the purine receptor, P2X7. P2X7 is a membrane ion channel highly expressed in immune cells. Signal transduction occurs via rapid cation exchange, plasma membrane depolarisation and increased intracellular calcium. Additionally, prolonged or repeated P2X7 stimulation leads to formation of a non-sel

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10

Khosla, Rajiv. "Gastrointestinal transit of dosage forms." Thesis, University of Nottingham, 1987. http://eprints.nottingham.ac.uk/12741/.

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This thesis describes the results from a series of studies designed to evaluate the gastrointestinal transit of oral dosage forms. The transit of placebo pellet and tablet formulations was monitored using the technique of gamma scintigraphy. The formulations were radiolabelled with either technetium-99m or indium-lil. Four parameters, two physiological and two pharmaceutical, were selected for investigation. All the studies were conducted in healthy male volunteers. The first study examined the influence of the supine position on the gastric emptying of pellets in fasted and fed subjects. Ther

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11

Daly, R. "Gastrointestinal bacteria : attachment and interactions." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398156.

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12

Pye, G. "Gastrointestinal pH and colorectal neoplasia." Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381466.

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13

Porter, Timothy Robin. "Molecular genetics of gastrointestinal cancer." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273741.

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14

Yates, Catherine Ann. "Gastrointestinal development and riboflavin deficiency." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312293.

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15

Woloshynowych, Maria. "Psychological preparation for gastrointestinal endoscopy." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287454.

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16

Poxon, Valerie Anne. "Gastrointestinal inflammation and mucus biosynthesis." Thesis, Birmingham City University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334499.

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17

Losson, B. J. "Immunological unresponsiveness to gastrointestinal nematodes." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372886.

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18

Mrowicki, Anna. "Disordered eating in gastrointestinal disorders." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/88064/.

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This thesis consists of three chapters, a literature review, an empirical paper, and a reflective paper. Chapter one is a critical review of case study research on Disordered Eating (DE) in Gastrointestinal disorders (GId). Following both database and manual searches, twelve case study reports, describing 29 cases, were included and reviewed. The case study data shows there be a relationship between DE and GId, though the nature and direction of this relationship remains unclear. Possible risk factors for the onset of DE behaviours in the GId population are identified and discussed, as are sug

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19

LePard, Kathy Jean. "Serotonergic control of gastrointestinal function /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487859879938908.

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20

Partridge, Stephen. "The gastrointestinal absorption of lead." Thesis, Aston University, 1986. http://publications.aston.ac.uk/14504/.

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21

Bennett, Ethelle. "Functional gastrointestinal disorders relations between psychosocial factors, symptoms and sensorimotor disturbance /." Connect to full text, 1999. http://hdl.handle.net/2123/410.

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Thesis (Ph. D.)-- University of Sydney, 1999.<br>Title from title screen (viewed Apr. 21, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Depts. of Psychological Medicine and Medicine. Includes tables. Includes bibliography. Also available in print form.

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22

Filho, Dilson da Silva Pereira. "Desinfecção de endoscópios através da utilização de água ácida eletrolítica (pesquisa prospectiva e in vitro)." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-09102014-093609/.

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O Glutarldeído é usado como desinfetante de endoscópios, mas por ser irritante, deve ser substituído por outro produto alternativo. A água ácida eletrolisada (AAE) possui efeito bactericida, tecnologia essa desenvolvida no Japão para lavadoras de endoscópios. No nosso estudo, a contaminação endoscópica após o seu uso clínico foi examinada através de cultura para bactérias, micobactérias e fungos, tanto antes quanto após a desinfecção com glutaraldeído por 20 minutos ou água ácida eletrolizada por 7 minutos. As colônias de bactérias foram identificadas e contadas após 48 horas de incubação a 37

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23

Carvallo, Michelena Alvaro, and Domínguez Jorge Luis Rojas. "Factores asociados a mal pronóstico en pacientes con sangrado digestivo bajo en un hospital público." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2016. http://hdl.handle.net/10757/621792.

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Introducción: El sangrado digestivo bajo (SDB) es una entidad cuyas tasas de complicaciones y mortalidad se han incrementado en las últimas décadas. Si bien se han identificado algunos factores relacionados a mal pronóstico, aún quedan variables por evaluar. Objetivo: Identificar factores de mal pronóstico en pacientes que presentaron SDB en el Hospital Nacional Edgardo Rebagliati Martins de Lima, Perú. Materiales y métodos: Se realizó un estudio observacional analítico de tipo cohorte retrospectivo. Se realizó un censo de todos los pacientes que presentaron SDB agudo entre Enero 2010 y Dicie

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24

Dadgar, Anoushiravan. "Studies on rat gastrointestinal neuropeptide Y." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/27410.

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A sensitive and specific radioimmunoassay (RIA) for Neuropeptide Y (NPY) was developed and quantitation, characterization and release studies were performed. The development of the RIA required the purification of the NPY tracer due to both multiple iodinated products resulting from the five tyrosine residues in its amino acid sequence, and the presence of unlabelled NPY. Ion-exchange and reverse phase high performance chromatography (HPLC) purification of ¹²⁵I-NPY were performed. Optimal purification of ¹²⁵I-NPY was achieved using a HPLC with a μBondapak C₈ column and a 45-50% acetonitrile c

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25

Brink, Gijs Robert van den. "Morphostasis of the adult gastrointestinal tract." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/85925.

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26

Georges, Jane Marie. "Distressing gastrointestinal symptoms in postmenopausal women /." Thesis, Connect to this title online; UW restricted, 1991. http://hdl.handle.net/1773/7275.

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27

Crooks, Colin J. "The epidemiology of upper gastrointestinal bleeding." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13394/.

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Background There have been many conflicting changes in the prevalence of the risk factors for upper gastrointestinal bleeding and therefore it is not clear what the current trends in mortality or incidence are, nor which factors are important in driving these trends. As populations in many countries are ageing with an increasing burden of co-morbidity, this thesis investigates whether the relationship between non gastrointestinal co-morbidity and upper gastrointestinal bleeding might be an explanation for current trends. I hypothesised that non gastrointestinal co-morbidity was responsible for

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28

Wixner, Jonas. "Gastrointestinal disturbances in hereditary transthyretin amyloidosis." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88745.

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Background Transthyretin amyloid (ATTR) amyloidosis is a systemic disorder caused by amyloid deposits formed by misfolded transthyretin (TTR) monomers. Two main forms exist – wild-type and hereditary ATTR amyloidosis, the latter associated with TTR gene mutations. Wild-type ATTR amyloidosis has a late onset and primarily cardiac manifestations, whereas hereditary ATTR amyloidosis is a rare autosomal dominant condition with a considerable phenotypic diversity. Both disorders are present all over the world, but endemic areas of the hereditary form are found in Sweden, Portugal, Brazil and Japan.

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29

Riddoch, C. J. "Exercise-induced gastrointestinal symptoms : hormonal involvement." Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335621.

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30

Henry, Brian T. "The barrier function of gastrointestinal mucus." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334550.

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31

Young, Catriona Jean. "Modulated enzyme expression in gastrointestinal nematodes." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318123.

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32

Macadam, Anglea Brenda. "Drug targeting in the gastrointestinal tract." Thesis, University of Brighton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306400.

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33

Reid, Keith. "Gastrointestinal motility in vection induced nausea." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299548.

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34

Patterson, David Mark. "Caprine responsiveness towards gastrointestinal nematode infection." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/15600.

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Studies were conducted using Scottish cashmere goats which were segregated into responsive and non-responsive individuals on the basis of ranked faecal egg count following artificial and natural gastrointestinal nematode infection. These studies demonstrate that caprine responsiveness is a relatively stable and heritable characteristic, largely unaffected by season and mode or site of infection. Initial comparative studies showed does to be considerably more susceptible to mixed artificial <I>teladorsagia circumcincta</I> and <I>Trichostrongylus vitrinus</I> infection than were ewes or worm-na

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35

Karpathakis, A. "Molecular profiling of gastrointestinal neuroendocrine tumours." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1461038/.

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Small intestinal neuroendocrine tumours (SI NETs) are the most common malignancy of the small intestine, however they remain poorly characterised and the underlying pathogenic mechanisms driving disease development have yet to be elucidated. Whole genome and exome sequencing has suggested SI NETs to be mutationally quiet, with the most frequent mutation in Cyclin Dependent Kinase 1B occurring in only 8% of tumours, suggesting mechanisms other than genetic mutations may be responsible for driving SI NET tumourigenesis. Using integrated genomic and epigenomic analysis three distinct somatic copy

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36

Moreira, Ricardo Filipe Silva. "Imunonutrição em doentes com cancro gastrointestinal." Bachelor's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4272.

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Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciado em Ciências da Nutrição<br>Objetivo: Fazer uma breve revisão da literatura sobre a importância da nutrição artificial, nomeadamente a imunonutrição, por via entérica, em doentes com cancro gastrointestinal, sujeitos ou não a cirurgia. Metodologia: Foi realizada uma pesquisa na base de dados da National Library of Medicine PUBMed-Medline e B-on, entre Abril e Outubro de 2013, utilizando-se os termos de pesquisa: “immunonutrition in gastrointestinal cancer surgery”, “e

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37

Eden, Kristin Beth. "Noncanonical NF-KB in Gastrointestinal Disease." Diss., Virginia Tech, 2011. http://hdl.handle.net/10919/86127.

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Noncanonical NF-KB is an alternative NF-KB pathway that is critically involved in the development and maturation of the adaptive immune system. As such, it has typically been studied in B and T cell biology without application to complex organ systems such as the gut. The following work explores the contribution of noncanonical NF-KB to inflammatory and neoplastic disease in the gastrointestinal (GI) system, as well as the effects of its loss on GI health. Chapter 1 opens with an overview of gastrointestinal homeostasis and inflammation, with emphasis on the particular diseases studied in this

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38

Eden, Kristin. "Noncanonical NF-KB in Gastrointestinal Disease." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/86127.

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Noncanonical NF-KB is an alternative NF-KB pathway that is critically involved in the development and maturation of the adaptive immune system. As such, it has typically been studied in B and T cell biology without application to complex organ systems such as the gut. The following work explores the contribution of noncanonical NF-KB to inflammatory and neoplastic disease in the gastrointestinal (GI) system, as well as the effects of its loss on GI health. Chapter 1 opens with an overview of gastrointestinal homeostasis and inflammation, with emphasis on the particular diseases studied in this

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39

Madden, Lisa J. "Pica and peptides : assessing gastrointestinal malaise /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/10637.

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40

Spear, Estelle Trego. "Altered Gastrointestinal Motility in Multiple Sclerosis." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/837.

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Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that causes motor, visual, and sensory symptoms. Patients also experience constipation, which is not yet understood, but could involve dysfunction of the enteric nervous system (ENS). Autoimmune targeting of the ENS occurs in other autoimmune diseases that exhibit gastrointestinal (GI) symptoms, and similar mechanisms could lead to GI dysfunction in MS. Here, we characterize GI dysmotility in the experimental autoimmune encephalomyelitis (EAE) model of MS and test whether autoantibodies targeting the ENS are present

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41

Andrews, Jane Mary. "Relationships between motor and sensory function in the proximal gut, appetite, & nutrients in healthy human subjects." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09pha567.pdf.

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Bibliography: leaves 206-251. The motor and sensory interactions between nutrients and proximal gut in humans are not well understood, despite the pivotal importance of these interactions on appetite, absorption and thus, nutrition. In part, this lack of knowledge results from technical difficulties in studying motor function in the human gut. In particular, the inability to continuously measure intraluminal flow with any degree of temporal resolution, has impeded progress in this field. The studies described in this thesis focus on nutrient-gut interactions, and also on the development of nov

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42

Dinis, João Vitor Barrau Mendes Ferreira. "Estratégias nutricionais na prevenção de doenças digestivas dos suínos." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2010. http://hdl.handle.net/10400.5/2573.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Depois da proibição do uso de promotores de crescimento em produção animal pela União Europeia em 2003, a suinicultura deparou-se com uma série de doenças que anteriormente estavam suprimidas, nomeadamente a nível do tracto gastrointestinal, devido à incorporação consecutiva de promotores de crescimento, ou seja, antibióticos nos alimentos compostos. Os actuais sistemas de produção de suínos têm um impacto importante nas funções, na integridade e na saúde do seu tubo digestivo, havendo uma diversidade de factores que a podem prejudic

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43

Martínez, Perea Vicente. "Función de CCK y de los lípidos en la regulación de la motilidad gastrointestinal en el pollo." Doctoral thesis, Universitat Autònoma de Barcelona, 1993. http://hdl.handle.net/10803/3827.

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44

Cassana, Abad Carla Alessandra, Silvia Scialom, Eddy R. Segura, and Alfonso Chacaltana. "Estudio de validación diagnóstica de la escala de Glasgow-Blatchford para la predicción de mortalidad en pacientes con hemorragia digestiva alta en un hospital de Lima, Perú (junio 2012-diciembre 2013)." Sociedad Española de Patología Digestiva, 2015. http://hdl.handle.net/10757/608517.

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Antecedentes y propósito del estudio: la hemorragia digestiva alta es una causa importante de ingreso hospitalario y constituye la principal emergencia gastroenterológica, con una tasa de mortalidad de hasta el 14%. En el Perú no existen estudios sobre el uso de la escala de Glasgow-Blatchford para predecir mortalidad por hemorragia digestiva alta. El objetivo de este estudio es realizar la validación externa de la escala de Glasgow-Blatchford y establecer su mejor punto de corte para predecir mortalidad por hemorragia digestiva alta en un hospital de Lima, Perú. Métodos: estudio de validació

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45

Njuguna, Peter. "Studies on the manipulation of gastrointestinal tract bacteria." Access electronically, 2005. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20060719.125402/index.html.

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46

Brauns, Seth Clint Aron. "Physiological and non-physiological induction of gastrointestinal differentiation." Thesis, University of Port Elizabeth, 1999. http://hdl.handle.net/10948/d1015521.

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The human colonic carcinoma cell lines HT-29 and Caco-2 both exhibit structural and functional differentiation under appropriate culture conditions. HT-29 can be induced to differentiate by treatment with short-chain fatty acids or acetoacetate. Caco-2 cells differentiate spontaneously upon contact inhibition. In this study HT-29 cells were treated with 5 mM acetate, propionate, butyrate and acetoacetate (physiological inducers) to assess their effects on the expression of carbonic anhydrase 1, sucrase-isomaltase and alkaline phosphatase which are reported to be markers of gastrointestinal dif

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47

Lopes, Marco A. F. "Hydration of Colonic Ingesta and Feces in Horses Fed Large Grain Meals or Treated with Enteral Fluid Therapy, Saline Cathartics and Intravenous Fluid Therapy." Diss., Virginia Tech, 2002. http://hdl.handle.net/10919/29338.

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Systemic hydration, plasma electrolytes, ingesta and fecal hydration and gastrointestinal passage of cobalt (after CoEDTA administration via nasogastric tube) in horses fed large grain meals or treated with enteral fluid therapy, IV fluid therapy and enteral laxatives were investigated. In the first study, 0.9% NaCl (10 L/h/8h) was administered slowly via a small-bore nasogastric tube or as 10 L boluses via a large-bore nasogastric tube to four normal horses. In the other studies, horses with a right dorsal colon fistula were used. To create the right dorsal colon fistula, a cannula with 5 cm

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48

Dahlhoff, Maik. "Actions of betacellulin in the gastrointestinal tract." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-98465.

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49

Karling, Pontus. "The emotional motor system and gastrointestinal symptoms." Doctoral thesis, Umeå universitet, Folkhälsa och klinisk medicin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1802.

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There is a significant comorbidity between anxiety/depression and functional gastrointestinal syndromes, such as irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. A model of an emotional motor system (EMS) which reacts to interoceptive and exteroceptive stress has been proposed. EMS consists of specific brain structures including anterior cingulate cortex (ACC), amygdala, hippocampus and hypothalamus and mediates their communication to the rest of the body (including the gastrointestinal tract) through the hypothalam

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Hedberg, Jakob. "Gastrointestinal Physiology and Results following Bariatric Surgery." Doctoral thesis, Uppsala universitet, Gastrointestinalkirurgi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131889.

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The number of operations for morbid obesity is rising fast. We have examined aspects of postoperative physiology and results after bariatric surgery. The pH in the proximal pouch after Roux-en-Y gastric bypass (RYGBP) was investigated with catheter-based and wire-less technique. Gastric emptying, PYY-levels in the fasting state and after a standardized meal was evaluated after biliopancreatic diversion with duodenal switch (DS). A clinical trial was undertaken, comparing DS to RYGBP in patients with BMI>48. Main outcome variables were safety and long-term weight results as well as abdominal

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