Gotowe bibliografie tematyczne / GATOR1 complex

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  1. Artykuły w czasopismach
  2. Rozprawy doktorskie
  3. Książki
  4. Części książek
  5. Streszczenia konferencji

Gotowa bibliografia na temat „GATOR1 complex”

Autor: Grafiati
Data publikacji: 28 września 2024
Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "GATOR1 complex"

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Bettedi, Lucia, Yingbiao Zhang, Shu Yang, and Mary A. Lilly. "Unveiling GATOR2 Function: Novel Insights from Drosophila Research." Cells 13, no. 21 (2024): 1795. http://dx.doi.org/10.3390/cells13211795.

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The multiprotein Target of Rapamycin (TOR) Complex 1 (TORC1) is a serine/threonine kinase that stimulates anabolic metabolism and suppresses catabolism. Deregulation of TORC1 is implicated in various human pathologies, including cancer, epilepsy, and neurodegenerative disorders. The Gap Activity Towards Rags (GATOR) complex contains two subcomplexes: GATOR1, which inhibits TORC1 activity; and GATOR2, which counteracts GATOR1s function. Structural and biochemical studies have elucidated how GATOR1 regulates TORC1 activity by acting as a GTPase activating protein for Rag GTPase. However, while c
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Kurrle, Nina, Frank Schnütgen, Juliana Heidler, et al. "Exploring the Function of Sestrin/Gator As Novel Regulators of Hematopoiesis." Blood 128, no. 22 (2016): 1484. http://dx.doi.org/10.1182/blood.v128.22.1484.1484.

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Abstract The mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase that responds to multiple environmental cues such as reactive oxygen species (ROS) and thereby regulates many fundamental biological processes including cell growth and autophagy. mTOR is found in two distinct multiprotein complexes, mTORC1 and mTORC2, of which mTORC1 has been established to play an important role in the regulation of hematopoiesis. For example, mTORC1 inhibition, combined with activation of canonical Wnt-signaling, was shown to increase long term repopulating (LT)-HSC self-renewal, whereas
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Muller, Maéline, Jasmine Bélanger, Imane Hadj-Aissa, Conghao Zhang, Chantelle F. Sephton, and Paul A. Dutchak. "GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1." International Journal of Molecular Sciences 25, no. 4 (2024): 2068. http://dx.doi.org/10.3390/ijms25042068.

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GATOR1 (GAP Activity TOward Rag 1) is an evolutionarily conserved GTPase-activating protein complex that controls the activity of mTORC1 (mammalian Target Of Rapamycin Complex 1) in response to amino acid availability in cells. Genetic mutations in the GATOR1 subunits, NPRL2 (nitrogen permease regulator-like 2), NPRL3 (nitrogen permease regulator-like 3), and DEPDC5 (DEP domain containing 5), have been associated with epilepsy in humans; however, the specific effects of these mutations on GATOR1 function and mTORC1 regulation are not well understood. Herein, we report that epilepsy-linked muta
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Wei, Youheng, Brad Reveal, Weili Cai, and Mary A. Lilly. "The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster." G3 Genes|Genomes|Genetics 6, no. 12 (2016): 3859–67. http://dx.doi.org/10.1534/g3.116.035337.

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Abstract TORC1 regulates metabolism and growth in response to a large array of upstream inputs. The evolutionarily conserved trimeric GATOR1 complex inhibits TORC1 activity in response to amino acid limitation. In humans, the GATOR1 complex has been implicated in a wide array of pathologies including cancer and hereditary forms of epilepsy. However, the precise role of GATOR1 in animal physiology remains largely undefined. Here, we characterize null mutants of the GATOR1 components nprl2, nprl3, and iml1 in Drosophila melanogaster. We demonstrate that all three mutants have inappropriately hig
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Haidurov, Alexander, and Andrei V. Budanov. "Locked in Structure: Sestrin and GATOR—A Billion-Year Marriage." Cells 13, no. 18 (2024): 1587. http://dx.doi.org/10.3390/cells13181587.

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Sestrins are a conserved family of stress-responsive proteins that play a crucial role in cellular metabolism, stress response, and ageing. Vertebrates have three Sestrin genes (SESN1, SESN2, and SESN3), while invertebrates encode only one. Initially identified as antioxidant proteins that regulate cell viability, Sestrins are now recognised as crucial inhibitors of the mechanistic target of rapamycin complex 1 kinase (mTORC1), a central regulator of anabolism, cell growth, and autophagy. Sestrins suppress mTORC1 through an inhibitory interaction with the GATOR2 protein complex, which, in conc
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Gu, Xin, Jose M. Orozco, Robert A. Saxton, et al. "SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway." Science 358, no. 6364 (2017): 813–18. http://dx.doi.org/10.1126/science.aao3265.

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mTOR complex 1 (mTORC1) regulates cell growth and metabolism in response to multiple environmental cues. Nutrients signal via the Rag guanosine triphosphatases (GTPases) to promote the localization of mTORC1 to the lysosomal surface, its site of activation. We identified SAMTOR, a previously uncharacterized protein, which inhibits mTORC1 signaling by interacting with GATOR1, the GTPase activating protein (GAP) for RagA/B. We found that the methyl donor S-adenosylmethionine (SAM) disrupts the SAMTOR-GATOR1 complex by binding directly to SAMTOR with a dissociation constant of approximately 7 μM.
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Padi, Sathish K. R., Neha Singh, Jeremiah J. Bearss, et al. "Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth." Proceedings of the National Academy of Sciences 116, no. 41 (2019): 20505–10. http://dx.doi.org/10.1073/pnas.1904774116.

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The Pim and AKT serine/threonine protein kinases are implicated as drivers of cancer. Their regulation of tumor growth is closely tied to the ability of these enzymes to mainly stimulate protein synthesis by activating mTORC1 (mammalian target of rapamycin complex 1) signaling, although the exact mechanism is not completely understood. mTORC1 activity is normally suppressed by amino acid starvation through a cascade of multiple regulatory protein complexes, e.g., GATOR1, GATOR2, and KICSTOR, that reduce the activity of Rag GTPases. Bioinformatic analysis revealed that DEPDC5 (DEP domain contai
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Solanki, Sumeet, Jun-Hee Lee, and Yatrik Shah. "AMINO ACID SENSING PATHWAYS IN INFLAMMATORY BOWEL DISEASE." Inflammatory Bowel Diseases 28, Supplement_1 (2022): S23—S24. http://dx.doi.org/10.1093/ibd/izac015.036.

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Abstract IBD is a chronic inflammatory disease of the gastrointestinal tract affecting millions of people worldwide. The last few decades have seen rapid increase of IBD cases in the US contributing to exorbitant health-care costs and morbidity rates. IBD comprises of two major subtypes: ulcerative colitis and Crohn’s disease. Although the etiology of IBD is not completely understood, a complex interaction of environmental, genetic, immune, and gut microbial factors contributes to its pathogenesis. These factors ultimately converge to disrupt intestinal epithelial cell homeostasis, compromisin
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Van ’t Hof, Femke, and Eva Brilstra. "Focale epilepsie en de GATOR1 complex genen." Epilepsie, periodiek voor professionals 19, no. 2 (2021): 11–13. http://dx.doi.org/10.54160/epilepsie.11027.

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Een monogene oorzaak bij focale epilepsie is minder zeldzaam dan vroeger werd gedacht. De meest voorkomende groep erfelijke, focale epilepsieën worden veroorzaakt door varianten in de GATOR1 complex genen (DEPDC5, NPRL2 en NPRL3), ook wel de ‘GATORopathieën’ genoemd. Er is steeds meer bekend over de verschillende ziekte-uitingen van deze aandoeningen, en zelfs over de consequenties voor behandeling. Dit maakt genetische diagnostiek belangrijk.
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Kovačević, Maša, Nikola Vojvodić, and Ivana Novaković. "GATOR1 gene variants in focal epilepsy." Medicinski podmladak 75, no. 3 (2024): 21–27. http://dx.doi.org/10.5937/mp75-45140.

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Significant genetic contributions to focal epilepsy have only recently been recognized, despite the well-established hereditary nature of other epilepsy syndromes. In 2013, the significant role of the DEPDC5 gene in a rare familial focal epilepsy syndrome was described, followed by the discovery of variants in NPRL2 and NPRL3 genes in patients with similar clinical features three years later. The genes listed above code the three subunits that comprise the GTPase-activating protein (GAP) activity towards Rags 1 (GATOR1) complex, a negative regulator of the mechanistic target of rapamycin (mTOR
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Rozprawy doktorskie na temat "GATOR1 complex"

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Pan, Zhenrui. "Functional characterization of the GATOR1 complex in cisplatin resistance." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL053.

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L'administration de cisplatine constitue la principale approche de chimiothérapie pour de nombreux cancers épithéliaux. Cependant, la résistance à ce médicament pose un défi considérable à un traitement efficace. Malgré l'identification de nombreux facteurs associés à la résistance aux médicaments, des biomarqueurs fiables permettant de prédire la réponse au traitement restent insaisissables. Auparavant, une faible expression du suppresseur de tumeur NPRL2 était liée à la résistance au cisplatine. NPRL2, ainsi que NPRL3 et DEPDC5, forment le complexe GATOR1, un régulateur en amont du complexe
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Zhang, Hanxiao. "The role of the GATOR1 complex in mitochondrial function and quality control." Electronic Thesis or Diss., université Paris-Saclay, 2025. http://www.theses.fr/2025UPASL033.

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La voie mTORC1 joue un rôle clé dans l'homéostasie cellulaire en intégrant des signaux provenant de diverses stimuli intracellulaires et extracellulaires. Parmi ses nombreuses fonctions, la régulation de l'homéostasie mitochondriale est l'une des plus complexes. mTORC1 est essentiel pour la biogenèse mitochondriale, la phosphorylation des protéines mitochondriales et la régulation de la mitophagie. La régulation de mTORC1 elle-même constitue un processus hautement complexe, influencé par de multiples modulateurs en amont et effecteurs en aval. Le complexe GATOR1, composé de NPRL2, NPRL3 et DEP
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Ma, Yinxing. "Functional characterization of tumor suppressors from the SEA / GATOR complex." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS275.

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La plupart des voies de signalisation qui régule la croissance cellulaire et le métabolisme sont sous le contrôle du mécanisme du complexe I de la rapamycine (mTORC1). L'un des régulateurs en amont de mTORC1, impliqués dans la détection des acides aminés et l'autophagie, est complexe SEA, chez la levure, et le complexe GATOR, chez les mammifères. Plusieurs composants de GATOR sont dérégulés dans de nombreux cancers et maladies neurodégénératives. Malgré l'intérêt scientifique vis à vis du complexe SEA / GATOR, de nombreux détails concernant sa fonction et son implication dans différents troubl
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Gonzalez, Alba. "On the edge between cell division and differentiation : role of Seh1 in mouse embryonic stem cells." Thesis, Université de Paris (2019-....), 2019. http://www.theses.fr/2019UNIP7039.

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Les complexes des pores nucléaires (NPCs) sont des larges structures macromoléculaires ancrées dans l'enveloppe nucléaire, et composées d'environ 30 protéines différentes appelées nucléoporines ou Nups. Au-delà de leur rôle critique dans le transport des molécules, les NPCs participent à une grande variété de processus biologiques, tels que la division cellulaire, l'organisation de la chromatine et la régulation de l'expression des gènes. Le principal sous-complexe structural des NPCs est le complexe Y-complexe, qui est composé de 9 nucléoporines distinctes. Le Y-complexe est aussi localisé au
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Bazzi, Talissa. "CARACTERÍSTICAS CLÍNICO-EPIDEMIOLÓGICAS, HISTOMORFOLÓGICAS E HISTOQUÍMICAS DA ESPOROTRICOSE FELINA." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/10218.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Sporotricosis is an acute or subacute mycotic infection caused by the Sporothrix complex species. The disease was already described in humans and in several animal species, mostly in cats, horses and dogs. Based on several outbreak reports in the literature, the species more predominant in cats of the Southeast and South regions of Brazil is S. brasiliensis. The transmission to humans include the occupational and the zoonotic forms. The presentation form more often seen in cats is multiple skin and mucosal lesions. The diagnostic m
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Oikonomopoulos, Spyridon. "Inferring structural properties of protein-DNA binding using high-throughput sequencing : the paradigm of GATA1, KLF1 and their complexes GATA1/FOG1 and GATA1/KLF1 : insights into the transcriptional regulation of the erythroid cell lineage." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:72b92906-4ef6-4c1d-9155-484521027e2e.

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GATA1 and KLF1 are transcription factors that regulate genes which are important for the development of erythroid cells. The GATA1 transcriptional co-factor FOG1 has been shown to be essential in a wide range of GATA1 dependent cellular functions. Here we tried to understand the diverse mechanisms by which GATA1 and KLF1 recognize their binding sites, how the GATA1 recognition mechanisms are affected by complexation with either FOG1 or KLF1 and how the GATA1 recognition mechanisms affect the transcriptional regulation of the erythroid differentiation. We profiled the DNA binding specificities/
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Vargas, Zúñiga Juan Alberto. "Reporte de un caso de epidermitis supurativa necrótica por Acinetobacter calcoaceticus - Acinetobacter baumannii (Acb-) complex en gato (Felis catus) en el Perú." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2017. https://hdl.handle.net/20.500.12672/11379.

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Manifiesta que el Acinetobacter baumannii es una bacteria responsable de infecciones nosocomiales con alta mortalidad en humanos, elevada tasa de resistencia a los antibióticos y con presentaciones reportadas en animales cada vez más frecuentes. Un gato doméstico pelo corto de 7 meses de edad y 4,4 kgs es llevado a la veterinaria por vómitos y decaimiento, al día siguiente regresa con temperatura de 40.1 °C, Posteriormente presenta linfadenomegalia únicamente de lado izquierdo (pre escapular, axilar, inguinal), además se hace evidente lesión cutánea alopécica en miembro anterior izquierdo, la
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Seki, Meire Christina [UNESP]. "Chlamydophila felis em gatos (Felis catus): detecção de antígeno e pesquisa de anticorpos." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/95975.

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Made available in DSpace on 2014-06-11T19:27:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-21Bitstream added on 2014-06-13T19:57:07Z : No. of bitstreams: 1 seki_mc_me_jabo.pdf: 576519 bytes, checksum: d22961f6b04eb42b3628b080392fb7c3 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O presente trabalho, primeiro estudo sobre clamidiose felina no Brasil, teve o objetivo de pesquisar a presença direta e indireta de Chlamydophila (elis em gatos domésticos provenientes de cinco municípios da região nordeste do estado de São Paulo. Adicionalmente, correlacio
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Abreu, Daniel Paiva Barros de. "Caracteriza??o fenot?pica, genot?pica e perfil de sensibilidade a antif?ngicos de isolados cl?nicos de c?es e gatos pertencentes ao Complexo Sporothrix schenckii oriundos do estado do Rio de Janeiro." Universidade Federal Rural do Rio de Janeiro, 2017. https://tede.ufrrj.br/jspui/handle/jspui/2031.

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Submitted by Celso Magalhaes (celsomagalhaes@ufrrj.br) on 2017-09-13T12:31:48Z No. of bitstreams: 1 2017 - Daniel Paiva Barros de Abreu.pdf: 1307092 bytes, checksum: b384d4db2cb316d3f640b111bc8efba4 (MD5)<br>Made available in DSpace on 2017-09-13T12:31:48Z (GMT). No. of bitstreams: 1 2017 - Daniel Paiva Barros de Abreu.pdf: 1307092 bytes, checksum: b384d4db2cb316d3f640b111bc8efba4 (MD5) Previous issue date: 2017-02-20<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico - CNPq<br>Dimorphic fungi belonging to Sporothrix schenckii complex are responsible for sporotrichosis, importa
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Dawson, Ruby Emily. "Investigation of the GATOR1 complex genes in focal cortical dysplasia and focal epilepsy." Thesis, 2019. http://hdl.handle.net/2440/121340.

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Epilepsy is a complex disease characterised by seizures due to abnormal neuronal activity. Both hereditable and non-hereditable epilepsy forms of epilepsy exist, and understanding their underlying mechanisms leads to more effective and targeted treatments. Following advances in DNA sequencing technologies, more cases of epilepsy caused by genetic mutations have been identified. Therefore, the investigation into how these mutations result in seizures is a worthwhile avenue of research, and will improve diagnosis and treatment of affected individuals. DEPDC5, NPRL2 and NPRL3 encode the GATOR1 co
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Książki na temat "GATOR1 complex"

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Pinto, Analía Verónica. Orozquianas. Editorial de la Universidad Nacional de La Plata (EDULP), 2017. http://dx.doi.org/10.35537/10915/59418.

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&lt;i&gt;Orozquianas&lt;/i&gt; apela a las nociones de reescritura y homenaje en forma explícita, algo que en la poesía suele hacerse de modo menos contundente. Aquí se ponen de relieve dichos recursos, como una forma de homenajear y agradecer tanta felicidad deparada por la lectura de la &lt;i&gt;Poesía completa&lt;/i&gt; de Olga Orozco, de donde fueron extraídos todos los versos utilizados como disparadores. El mundo de Orozco, así, es revelado a través de la admiración y la apropiación poética de algunos de sus íconos (como el otoño o los gatos), conformando un nuevo caleidoscopio, que tamb
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Części książek na temat "GATOR1 complex"

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Ivanova, Ilina, and Kuang Shen. "Structures and Functions of the Human GATOR1 Complex." In Subcellular Biochemistry. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-58843-3_12.

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Tariq, Hasan, Farid Touati, Mohammed Abdulla E. Al-Hitmi, Damiano Crescini, and Adel Ben Mnaouer. "A Multi-Agent Infrastructure Monitoring IoT System for Urban Geo-Resilience Framework." In Multi-agent Systems - From Basic Concepts to Cutting-Edge Technologies [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1009973.

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Multi-agent systems (MAS) have emerged as a cornerstone technology in developing agile and effective resilience frameworks for geo-distributed ecosystems. These systems play a pivotal role in addressing real-time challenges in Structural Health Monitoring (SHM), where millions of distributed data-processing tasks must be executed swiftly/parrallel to ensure system resilience. Core functionalities in this context include resolving complex sustainability conflicts, detecting and characterizing anomalies in chaotic datasets, and formulating adaptive and unique resilience strategies. This work pre
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Brito, Giovana Fernandes Medeiros de, Leticia Mariana Leontsinis Andrade, Reginaldo Pereira de Sousa Filho, and Paulo Ricardo Monteiro Araújo. "DOENÇA PERIODONTAL E COMPLEXO GENGIVITE ESTOMATITE FELINA EM GATO DOMÉSTICO: RELATO DE CASO." In V CAFÉ COM CLÍNICA: Indo Além do Atendimento de Rotina. Editora In Vivo, 2025. https://doi.org/10.47242/978-65-87959-57-3-9.

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Galvão, André Luiz Baptista, Ernesto Calle Colina, André Ivan Minatel Ramos da Silva, and Yarima Garcia de Andrade. "CUIDADOS DESDE A OBTENÇÃO DA AMOSTRA DE SANGUE ATÉ O SEU PROCESSAMENTO LABORATORIAL PARA FINS DE AVALIAÇÃO DO PERFIL HEMATOLÓGICO DE CÃES E GATOS." In Biologia Geral: Uma Visão Integrada dos Sistemas da Vida. Editora Impacto Científico, 2025. https://doi.org/10.56238/edimpacto2024.003-001.

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O perfil hematológico, possui como meios de sua composição o perfil eritrocitário, o perfil leucocitário e o perfil plaquetário, constituindo em uma avalição básica de avaliação do paciente, mas de grande importância. O denominado “Hemograma” constitui no perfil hematológico completo, por meio dele podemos ter a identificação de achados laboratoriais importantes. Como nos casos dos diferentes graus de anemia, a identificação da eritrocitose, leucocitose, trombocitopenia e trombocitose. Os achados encontrado no perfil hematológico podem possuir várias etiologias, merecendo atenção as condições
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Moreira, Jefferson Santos Gomes, Nicolas Vieira Guerra Castilho, Tania Sueli Andrade, and Lumena Pereira Machado Siqueira. "RECARACTERIZAÇÃO DE LINHAGENS DO COMPLEXO SPOROTHRIX SCHENCKII DO NÚCLEO DE COLEÇÕES DE MICRO-ORGANISMOS POR MEIO DA METODOLOGIA MALDITOF COM CONSTRUÇÃO DE BANCO IN-HOUSE." In Saúde pública em foco: Pesquisas e inovações. AGRONFY, 2025. https://doi.org/10.53934/agronfy-2025-02-17.

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Resumo: A esporotricose é uma doença zoonótica causada pelo fungo termodimórfico Sporothrix schenckii, que afeta principalmente humanos e gatos, mas, pode acometer também outros animais de sangue quente. A transmissão ocorre por contato traumático com fontes contaminadas, como mordeduras ou arranhaduras de animais infectados e vegetação contaminada. O aumento progressivo dos casos levou à sua classificação como notificação compulsória no estado de São Paulo, especialmente devido à emergência do agente etiológico Sporothrix brasiliensis, que se mostrou mais patogênico que o Sporothrix schenckii
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Leal, Janaina de Fatima Rodrigues, and Fabiane Schneider. "Parceria da gestão pública e do terceiro setor nas políticas públicas de proteção animal." In Administração Contemporânea Vol 4, 4th ed. Editora ZH4, 2021. http://dx.doi.org/10.51360/zh4.20218-8-p19-31.

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Esta pesquisa tem como objetivo a análise das vantagens de se aliar a gestão pública ao trabalho do terceiro setor, e mais especificamente sobre a contribuição da AMAHTEB (Associação dos Amigos do Melhor Amigo do Homem para o Bem-Estar Animal de Telêmaco Borba) em políticas públicas de proteção animal e controle ético da população de cães e gatos, conforme dispõe a Lei 17422 de 18 de dezembro de 2012 no município de Telêmaco Borba/PR. Desta forma, se direcionando a ampliar a visão a respeito do aumento da população de animais de rua no município, e em decorrência disso a proliferação de zoonos
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Queiroz, Bruna Barros de, Laís Macêdo Maciel, Gabriel Lúcio Guimarães dos Santos, Caio Victor Barros Gonçalves da Silva, Maria Júlia Brito Couto, and Beatriz Santana Rocha. "Os avanços no tratamento da doença falciforme através da terapia gênica com CRISPR/CAS9." In Avanços em Genética Humana um panorama do 1° simpósio da LAGH. Instituto Internacional Despertando Vocações, 2024. http://dx.doi.org/10.31692/978-65-88970-44-7.26-28.

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A doença falciforme (DF) é uma hemoglobinopatia causada por uma mutação estrutural hereditária na formação das cadeias globínicas1 . Essa alteração ocorre por uma mutação pontual A/T na posição 6 do gene da β globina, causando a troca do aminoácido ácido glutâmico pela valina, resultando na síntese da cadeia variante bS globina, que compõe a Hemoglobina S (HbS)2 . A baixa tensão de oxigênio leva à polimerização da HbS, mudando a estrutura da hemácia, inicialmente bicôncava, para falciforme, facilitando a agregação, resultando em oclusão vascular, hipóxia, risco de AVC, esplenomegalia, úlceras
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Streszczenia konferencji na temat "GATOR1 complex"

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Pereira, Thainá da Silva, Maria Eduarda Monteiro Silva, Fernando Luíz Fernandes Mendes, Rafael Rempto Pereira, Mayara de Souza Teixeira da Costa, and Gabriel Bobany de Queiroz. ""ACHADOS HEMATOLÓGICOS EM GATOS TESTADOS POSITIVOS PARA FELV - ESTUDO RETROSPECTIVO"." In XXXIII Jornada Científica da Medicina Veterinária. Even3, 2025. https://doi.org/10.29327/1505793.33-3.

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"O Vírus da Leucemia Felina é um vírus disseminado mundialmente, onde se trata de um Retrovírus. A FeLV pode evoluir para quatro tipos de infecções, sendo elas a infecção progressiva, regressiva, abortiva e atípica ou focal, e sua evolução vai depender do sistema imunológico do felino e do subgrupo que esteja acometendo esse paciente. Seus sinais clínicos são inespecíficos e o diagnóstico pode ser feito através de ELISA, Imunocromatofragia, Imunofluorescência Indireta e PCR, juntamente do hemograma completo e associado ao exame clínico. Neoplasias como linfomas e leucemias podem surgir, pois o
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Pedrete, Anna Clara Gomes, Bethânia Ferreira Bastos, Fernando Luíz Fernandes Mendes, Tatiana Didonet Lemos, Michele Vieira de Azeredo, and Rafael Rempto Pereira. ""DOENÇA INFLAMATÓRIA INTESTINAL EM FELINO DOMÉSTICO DA RAÇA PERSA: RELATO DE CASO"." In XXXIII Jornada Científica da Medicina Veterinária. Even3, 2025. https://doi.org/10.29327/1505793.33-19.

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A doença inflamatória intestinal é uma das patologias mais frequentes na rotina médica felina, sendo um conjunto de distúrbios gastrintestinais idiopáticos e de caráter crônico. A etiopatogenia da doença é diversa, envolvendo complexas interações entre fatores genéticos, ambientais, dietéticos e resposta imune. As manifestações clínicas são variadas e inespecíficas, como episódios de vômito, diarreia, perda de peso e dor abdominal. O diagnóstico diferencial e definitivo consiste em exclusão de outras etiologias com sintomatologia e achados clínicos similares, como o linfoma alimentar. Utiliza-
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Sabnis, Amit J., David V. Allegakoen, and Trever G. Bivona. "Abstract 3656: The mTOR-activating GATOR2 complex is essential inPAX3-FOXO1-positive rhabdomyosarcoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3656.

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Sabnis, Amit J., David V. Allegakoen, and Trever G. Bivona. "Abstract 3656: The mTOR-activating GATOR2 complex is essential inPAX3-FOXO1-positive rhabdomyosarcoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3656.

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Young, Sarah, Michael McClure, and Ursula Emery McClure. "GATOR House: A Typology of Resilience." In 108th Annual Meeting Proceedings. ACSA Press, 2020. http://dx.doi.org/10.35483/acsa.am.108.43.

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In the modern era, most buildings in southern Louisiana’s wet, hot, humid, and often volatile climate seek to resist the extreme conditions by creating a presumed impenetrable barrier. Since the advent of HVAC, levees, dams, and surge barriers, a construction culture of resistance has permeated the built environment. This has proven less than resilient and has resulted in billions of dollars in remediation and billions more tons of construction debris. Historically, buildings in this subtropical area were forced to employ every manner of passive systems to mediate their physical environment to
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Karla Alves da Silva, Jéssica, Rebeca Santana Malheiros, and Mary'Anne Rodrigues de Souza. "ESPOROTRICOSE CONJUNTIVAL EM UM FELINO DOMÉSTICO." In Congresso Online Acadêmico de Medicina Veterinária. Congresse.me, 2022. http://dx.doi.org/10.54265/folq8411.

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Introdução Esporotricose é uma micose causada por fungos pertencentes ao complexo Sporothrix schenckii. A infecção pode acontecer pela Inoculação do fungo na pele ou inalação de conídios (menos frequente). Os sinais clínicos variam desde lesão única ou lesões múltiplas até a forma sistêmica. A forma mais frequente é apresentada por múltiplas lesões cutâneas com envolvimento da mucosa nasal, as mucosas conjuntival, oral e genital também podem ser afetadas. Achados oftalmológicos como uveíte granulomatosa, retinite granulomatosa, coroidite e endoftalmite foram relatados em pacientes humanos. Obj
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Medrano, L., J. R. Spinelli, and A. R. Bertuccelli. "Sustainability and the megacities: the Gato Park Housing Complex in São Paulo, Brazil." In SUSTAINABLE DEVELOPMENT 2009. WIT Press, 2009. http://dx.doi.org/10.2495/sdp090071.

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Watanabe, Paola Tieko Chiozzi, Gabriel de Amorim Marques, Izabella Machado Casado, Gabrieli Junqueira Gonçalves, Danielli Aparecida Lavelli, and Leonardo Martins Leal. "Fratura completa de tíbia em canino filhote tratado com tala: relato de caso." In II Congresso Internacional Interdisciplinar da Uningá. Editora Uningá, 2023. http://dx.doi.org/10.46311/ed.un.20221018198.

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As fraturas são comuns na rotina de cães e de gatos. Seu diagnóstico se baseia na anamnese e exame físico ortopédico. Sua confirmação é feita pelo exame radiográfico. A osteossíntese é o tratamento de eleição na maioria dos casos, porém, em situações específicas, pode-se realizar o manejo das fraturas de tíbia com o uso de tala. Objetivou-se relatar o caso de um cão jovem com fratura completa de tíbia direita, que obteve rápida consolidação óssea somente com o uso de tala. Tal fato foi possível pois a fíbula direita não fraturou, o que possibilitou a manutenção do alinhamento interno do membro
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Reis, Ronan Pereira dos, Amanda Raiane de Castro Costa, and Mireille Ângela Bernardes Sousa. "Infecção dos seios da face causada por Sporothrix schenckii complex em paciente imunocompetente." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.10509.

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Objetivo: A esporotricose é uma micose subcutânea de distribuição global causada por algumas espécies do gênero Sporothrix spp. A forma extracutânea é rara, podendo ser causada por inalação de conídios ou disseminação hematogênica em decorrência de inoculação profunda na pele. Método: Estudo descritivo, relatando o caso de um paciente cujo material biológico foi enviado para análise, havendo crescimento de Sporothrix schenckii complex. Conclusão: Paciente imunocompetente, 18 anos, morador do Rio de Janeiro, repositor em supermercado localizado em região na qual residem vários gatos. Procurou a
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Marinho, Bruna Sthephany dos Santos. "COMPARAÇÃO CLÍNICA DE AMOSTRAS MICÓTICAS DE GATOS DOMÉSTICOS (FELIS CATUS): ESPOROTRICOSE E CRIPITOCOCOSE." In I Congresso Brasileiro On-line Multiprofissional de Análises Clínicas e Laboratoriais. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conalab/7839.

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Introdução: A esporotricose (complexo Sporothrix sp.) e a criptococose (Cryptococcus sp.) são doenças fúngicas induzidas por leveduras. Elas causam lesões de forma aguda ou crônica nos tecidos dos mamíferos como principal meio de manifestação clínica. Ambas de carater zoonótico, sendo o gato a espécie mais suceptível a elas. São dermatologicamente idênticas e, portanto, de diagnóstico macroscópico impreciso. Elas clinicamente possuem morfologias microscópicas semelhantes, e por isso são a maior causa de confusão no diagnóstico durate a fase analítica. Embora isto, elas apresentam particularida
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