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Artykuły w czasopismach na temat "Glutathione"

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Rubino, Federico Maria. "The Redox Potential of the β-93-Cysteine Thiol Group in Human Hemoglobin Estimated from In Vitro Oxidant Challenge Experiments". Molecules 26, № 9 (2021): 2528. http://dx.doi.org/10.3390/molecules26092528.

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Glutathionyl hemoglobin is a minor form of hemoglobin with intriguing properties. The measurement of the redox potential of its reactive β-93-Cysteine is useful to improve understanding of the response of erythrocytes to transient and chronic conditions of oxidative stress, where the level of glutathionyl hemoglobin is increased. An independent literature experiment describes the recovery of human erythrocytes exposed to an oxidant burst by measuring glutathione, glutathione disulfide and glutathionyl hemoglobin in a two-hour period. This article calculates a value for the redox potential E0 o
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Jones, C. M., A. Lawrence, P. Wardman, and M. J. Burkitt. "Kinetics of superoxide scavenging by glutathione: an evaluation of its role in the removal of mitochondrial superoxide." Biochemical Society Transactions 31, no. 6 (2003): 1337–39. http://dx.doi.org/10.1042/bst0311337.

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Superoxide radicals are produced in trace amounts by the mitochondrial respiratory chain. Most are removed rapidly by superoxide dismutase in the matrix. Superoxide is also known to react with glutathione. Reported values of the rate constant for this reaction range from 102 to in excess of 105 M−1·s−1. The magnitude of this rate constant has important physiological implications because, if it is at the upper end of the reported range, a significant proportion of mitochondrial superoxide will evade removal by superoxide dismutase, and will oxidize glutathione to the potentially harmful glutath
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Smith, K., A. Borges, M. R. Ariyanayagam, and A. H. Fairlamb. "Glutathionylspermidine metabolism in Escherichia coli." Biochemical Journal 312, no. 2 (1995): 465–69. http://dx.doi.org/10.1042/bj3120465.

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Intracellular levels of glutathione and glutathionylspermidine conjugates have been measured throughout the growth phases of Escherichia coli. Glutathionylspermidine was present in mid-log-phase cells, and under stationary and anaerobic growth conditions accounted for 80% of the total glutathione content. N1,N8-bis(glutathionyl)spermidine (trypanothione) was undetectable under all growth conditions. The catalytic constant kcat/Km of recombinant E. coli glutathione reductase for glutathionylspermidine disulphide was approx. 11,000-fold lower than that for glutathione disulphide. The much higher
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Sardari, Veronica, Valeriana Pantea, Aurelian Gulea, et al. "Thiol-disulfide metabolism in kidney tissue at the administration of some copper coordination compounds." Moldovan Medical Journal 63 (2) (May 30, 2020): 12–17. https://doi.org/10.5281/zenodo.3865976.

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<strong>Background: </strong>Thiol-disulfide metabolism is essential for normal function of the organism. Thus the interest of the scientists in this area of research continues to grow. <strong>Material and methods: </strong>Copper coordination compounds (CCC), derivatives of thiosemicarbaside (CMD-4, CMJ-33, CMT-67), action on thiol-disulfide metabolism in the healthy <em>Ratta albicans</em> kidneys were studied. The animals were divided in 6 groups of 7 rats each. The control group included healthy rats which were injected i/m physiological solution 3 times a week, for 30 days. The rats from
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Iskusnykh, Igor Y., Anastasia A. Zakharova, and Dhruba Pathak. "Glutathione in Brain Disorders and Aging." Molecules 27, no. 1 (2022): 324. http://dx.doi.org/10.3390/molecules27010324.

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Glutathione is a remarkably functional molecule with diverse features, which include being an antioxidant, a regulator of DNA synthesis and repair, a protector of thiol groups in proteins, a stabilizer of cell membranes, and a detoxifier of xenobiotics. Glutathione exists in two states—oxidized and reduced. Under normal physiological conditions of cellular homeostasis, glutathione remains primarily in its reduced form. However, many metabolic pathways involve oxidization of glutathione, resulting in an imbalance in cellular homeostasis. Impairment of glutathione function in the brain is linked
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van Hylckama Vlieg, Johan E. T., Hans Leemhuis, Jeffrey H. Lutje Spelberg, and Dick B. Janssen. "Characterization of the Gene Cluster Involved in Isoprene Metabolism in Rhodococcus sp. Strain AD45." Journal of Bacteriology 182, no. 7 (2000): 1956–63. http://dx.doi.org/10.1128/jb.182.7.1956-1963.2000.

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ABSTRACT The genes involved in isoprene (2-methyl-1,3-butadiene) utilization in Rhodococcus sp. strain AD45 were cloned and characterized. Sequence analysis of an 8.5-kb DNA fragment showed the presence of 10 genes of which 2 encoded enzymes which were previously found to be involved in isoprene degradation: a glutathioneS-transferase with activity towards 1,2-epoxy-2-methyl-3-butene (isoI) and a 1-hydroxy-2-glutathionyl-2-methyl-3-butene dehydrogenase (isoH). Furthermore, a gene encoding a second glutathioneS-transferase was identified (isoJ). TheisoJ gene was overexpressed in Escherichia col
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Miteva, L. P.-E., S. V. Ivanov, V. S. Alexieva, and E. N. Karanov. "Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants." Plant Protection Science 40, No. 1 (2010): 160–20. http://dx.doi.org/10.17221/1352-pps.

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Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it. The activities of two enzymes related to glutathione metabolism (glutathione reductase and glutathione S-transferase) were also determined. The application of the herbicide on leaf increased the levels of total and oxidised glutathione in pea and wheat plants. Increased activity glutathione S-transferase in wheat plants was found.
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Gutyj, B. V., D. F. Gufriy, V. Y. Binkevych, et al. "Influence of cadmium loading on glutathione system of antioxidant protection of the bullocks’bodies." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 92 (2018): 34–40. http://dx.doi.org/10.32718/nvlvet9207.

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It was presented the results of studies of the cadmium effect loading on the activity of the glutathione system of antioxidant protection in young cattle, namely on the activity of glutathione peroxidase, glutathione reductase, glucose-6-phosphate dehydrogenase, the level of reduced glutathion. It was established that feeding of cadmium chloride to bullocks at a dose of 0.03 and 0.05 mg/kg body weight contributed to a decrease in both the enzyme and non-enzyme link of the glutathione antioxidant defense system. The toxic effect of cadmium contributes to a change in stationary concentrations of
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Kulinsky, V. I., and L. S. Kolesnichenko. "The glutathione system. I. Synthesis, transport, glutathione transferases, glutathione peroxidases." Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 3, no. 2 (2009): 129–44. http://dx.doi.org/10.1134/s1990750809020036.

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Gaullier, J. M., P. Lafontant, A. Valla, M. Bazin, M. Giraud, and R. Santus. "Glutathione Peroxidase and Glutathione Reductase Activities toward Glutathione-Derived Antioxidants." Biochemical and Biophysical Research Communications 203, no. 3 (1994): 1668–74. http://dx.doi.org/10.1006/bbrc.1994.2378.

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Rozprawy doktorskie na temat "Glutathione"

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Petit, Elise. "Etude des Glutathion Transférases : caractérisation de la classe Kappa et rôle de ces enzymes dans l'hépatotoxicité des Thiopurines." Rennes 1, 2007. http://www.theses.fr/2007REN1B072.

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Les Glutathion Tranférases (GST) constituent un système multienzymatique de détoxication. Elles sont impliquées dans la prévention , le développement des tumeurs et dans la réponse aux anticancéreux. Pendant ma thèse , je me suis intéressée à la GST de classe Kappa. Sa caractérisation nous a permis de mettre en évidence sa présence dans les mitochondries et les peroxysomes. Cette localisation particulière suggère que le GST Kappa pourrait avoir un rôle lié aux fonctions cellulaires de ces deux organites. Les GST étant en outre impliquées dans des phénomènes de résistance à des anticancéreux, j
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Van, Eldik Annamaria Johanna. "Synthesis of glutathione conjugates as selective inhibitors for parasitic glutathione S transferases." Thesis, De Montfort University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246521.

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Halfwassen, Kathrin. "Untersuchungen zu Glutathion-sensitiven Farbstoffen in der Meerschweinchen-Retina." Doctoral thesis, Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-89656.

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Die Glutathionverhältnisse und -verschiebungen zwischen Gliazellen und Ganglienzellen vor und nach oxidativem Stress wurden erstmals im lebenden Zellverband, ex vivo, untersucht. Die Untersuchungen erfolgten an akut isoliertem Retinagewebe vom Meerschweinchen, von welchem Bilder am Laser scanning microscope (LSM) erstellt wurden. Über die Anwendung des in vivo-Fluoreszenzfarbstoffes CellTracker Green wurde dabei dessen Spezifität für Glutathion überprüft und bestätigt.
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Yang, Bo. "Biliary glutathione transport pathways." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0019/MQ52967.pdf.

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Lyon, Robert Patrick. "Enzymology at the dimer interface of cytosolic glutathione S-transferases /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/8165.

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Kearns, Pamela Renate. "The role of glutathione and mu class glutathione s-transferases in childhood acute leukaemia." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311134.

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Fläring, Urban. "Glutathione during stress in man /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-799-5/.

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Patzewitz, Eva-Maria. "Glutathione metabolism of Plasmodium falciparum." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/913/.

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Apicomplexan parasites of the genus Plasmodium are the causative agent of malaria, one of the most prevalent infectious diseases worldwide. Five different Plasmodium species can cause malaria in humans, leading to a total of approximately 500 million cases each year and of these, P. falciparum causes the most deadly form of the disease and is responsible for more than 1 million deaths annually. A major problem in the global fight against malaria is the widespread resistance of the parasites against the currently available drugs. It is of great importance to identify new drug target as well as
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Evans, D. C. "Renal processing of glutathione conjugates." Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383757.

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Di, Ilio C. "Studies on bacterial glutathione transferase." Thesis, Cranfield University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333472.

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Książki na temat "Glutathione"

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1940-, Dolphin David, Avramović Olga, and Poulson Rozanne, eds. Glutathione. Wiley, 1989.

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1940-, Dolphin David, Avramović Olga, and Poulson Rozanne, eds. Glutathione. Wiley, 1989.

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1942-, Sies H., and Ketterer Brian, eds. Glutathione conjugation: Mechanisms and biological significance. Academic Press, 1988.

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C, Awasthi Yogesh, ed. Toxicology of glutathione transferases. CRC\Taylor & Francis, 2007.

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Eldik, Annamaria Johanna van. Synthesis of glutathione conjugates as selective inhibitors for parasitic glutathione s-transferases. De Montfort University, 2002.

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1953-, Viña José, ed. Glutathione: Metabolism and physiological functions. CRC Press, 1990.

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1953-, Viña José, ed. Glutathione: Metabolism and physiological functions. CRC Press, 1990.

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A, Shaw Christopher, ed. Glutathione in the nervous system. Taylor & Francis, 1998.

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J, Mantle T., Pickett C. B, Hayes J. D, and Cancer Research Campaign (Great Britain), eds. Glutathione S-transferases and carcinogenesis. Taylor & Francis, 1987.

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D, Tew Kenneth, ed. Structure and function of glutathione transferases. CRC Press, 1993.

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Części książek na temat "Glutathione"

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Rosado, Leonardo Astolfi, Brandán Pedre, and Joris Messens. "Mycothiol, a Low-Molecular-Weight Thiol Drafted for Oxidative Stress Defense Duty." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-24.

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Comini, Marcelo A. "Biosynthesis of Polyamine–Glutathione Derivatives in Enterobacteria and Kinetoplastida." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-22.

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Hugo, Martin, Madia Trujillo, Lucía Piacenza, and Rafael Radi. "Trypanothione Functions in Kinetoplastida." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-23.

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Tung, Quach Ngoc, Nico Linzner, Vu Van Loi, and Haike Antelmann. "Biosynthesis and Functions of Bacillithiol in Firmicutes." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-25.

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Forman, Henry J., Hongqiao Zhang, and Terrance J. Kavanagh. "Biosynthesis of Glutathione and Its Regulation." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-1.

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Schomburg, Lutz. "Glutathione Peroxidases and the Thyroid Gland." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-10.

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Mannervik, Bengt, and Birgitta Sjödin. "Glutathione Transferases." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-11.

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Tew, Kenneth D. "Protein S-Glutathionylation and Glutathione S-Transferase P." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-12.

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Morgenstern, Ralf, Jesper Z. Haeggström, Per-Johan Jakobsson, and Leopold Flohé. "The Role of Glutathione in Biosynthetic Pathways and Regulation of the Eicosanoid Metabolism." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-13.

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Buxton, Iain L. O., and Scott D. Barnett. "Nitric Oxide and S-Nitrosoglutathione." In Glutathione. CRC Press, 2018. http://dx.doi.org/10.1201/9781351261760-14.

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Streszczenia konferencji na temat "Glutathione"

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Demopoulos, Harry B., Myron L. Seligman, Brent L. Summers, Jeremy Ollerenshaw, and John P. Richie,Jr. "Rapid, Safe, Substantial Repletion Of Intracellular Glutathione In Patients With Aquired Glutathione Insufficiency, Employing Orally Bioavailable, Pharmaceutical Glutathione." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1382.

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Kulikova, D. B., V. O. Nosova, and A. A. Tishchenko. "FEATURES OF THE GLUTATHIONE REDOX SYSTEM IN PATIENTS AFTER CORONAVIRUS INFECTION." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-342.

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COVID-19 includes a wide range of clinical signs and symptoms ranging from asymptomatic infections to acute respiratory distress. The glutathione redox system, represented in the human body by the enzymes glutathione-S-transferase (GST), glutathione peroxidase (GPO), and glutathione reductase (GR), provides antioxidant protection for cells. Oxidative stress plays a significant role in the course of coronavirus infection, therefore, an assessment of the state of the glutathione redox system allows us to draw conclusions about the presence and severity of oxidative stress in sick patients. In ad
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Bastiaens, Philippe I., Arie van Hoek, Jean-Claude Brochon, and Antonie J. W. G. Visser. "Conformational dynamics in glutathione reductase." In OE/LASE '92, edited by Joseph R. Lakowicz. SPIE, 1992. http://dx.doi.org/10.1117/12.58216.

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Pokidova, Olesya Viktorovna, Nina Sergeevna Emel’yanova, Alexander Vasilievich Kulikov, Alexander Ivanovich Kotelnikov, and Natalia Alekseevna Sanina. "STUDY OF THE TRANSFORMATION OF NITROSYL IRON COMPLEX WITH N-ETHYLTHIOUREA LIGANDS IN MODEL BIOLOGICAL SYSTEMS." In NEW TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2021. http://dx.doi.org/10.47501/978-5-6044060-1-4.52.

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The process of transformation of a mononuclear cationic complex with N-ethylthiourea ligands in Tris-HCl buffer, as well as in a reaction mixture with reduced glutathione and bovine serum albumin, has been studied. It was found that in the presence of glutathione, the complex dimer-izes, while its initial ligands are replaced by glutathione. In the presence of albumin, the decay product of the complex is coordinated with amino acid residues (Cys34 and His39) to form a protein-bound complex.
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Chomoucka, Jana, Jana Drbohlavova, Vojtech Adam, Rene Kizek, and Jaromir Hubalek. "Synthesis of glutathione-coated quantum dots." In 2009 32nd International Spring Seminar on Electronics Technology (ISSE). IEEE, 2009. http://dx.doi.org/10.1109/isse.2009.5206958.

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Paulíková, Helena, Dušan Podhradský, Marian Sabol, and Andrea Tóthová. "Glutathione levels in K562 leukemia line." In VIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199903044.

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Chang-Cheng Gao, Xian-Feng Zou, Qiong Wu, Xing Chen, Li-Hong Zhang, and Li-Na Chen. "A novel micromolecule glutathione peroxidase mimic." In 2011 International Symposium on Information Technology in Medicine and Education (ITME 2011). IEEE, 2011. http://dx.doi.org/10.1109/itime.2011.6132096.

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Voskresenska, Natalja, Julija Voicehovska, Sergejs Babikovs, et al. "Glutathione level in community-acquired pneumonia patients." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa988.

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ARDUINI, F., F. RICCI, G. PALLESCHI, D. MOSCONE, and A. AMINE. "MODIFIED SCREEN PRINTED ELECTRODES FOR GLUTATHIONE DETECTION." In Proceedings of the 9th Italian Conference. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812701770_0011.

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Yan, Haitao, and Weining Wang. "Terhertz time-domain spectroscopy of L-Glutathione." In Fourth International Conference on Photonics and Imaging in Biology and Medicine, edited by Kexin Xu, Qingming Luo, Da Xing, Alexander V. Priezzhev, and Valery V. Tuchin. SPIE, 2006. http://dx.doi.org/10.1117/12.710679.

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Raporty organizacyjne na temat "Glutathione"

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บัวบูชา, ธีรพงษ์, ศุภอรรจ ศิริกันทรมาศ та นุชนาถ วุฒิประดิษฐกุล. การค้นหายีนที่ควบคุมโดยโปรตีนคัลมอดุลินในการตอบสนองต่อสภาวะความเครียดจากสิ่งแวดล้อมของข้าว Oryza sativa L. : รายงานวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2015. https://doi.org/10.58837/chula.res.2015.58.

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การวิเคราะห์โปรติโอมิกส์เชิงเปรียบเทียบของข้าว (Oryza sativa L.) ทรานส์เจนิกสายพันธุ์ขาวดอกมะลิ 105 ที่มีการแสดงออกของยีน OsCam1-1 เกินปกติซึ่งแสดงลักษณะทนเค็ม สามารถระบุโปรตีนที่แสดงออกแตกต่างกับข้าว wild-type จำนวน 77 ชนิด ผลการวิเคราะห์ระดับการแสดงออกทรานสคริปของยีน LOC_Os02g11820 ที่สร้าง GTPase-activating protein ซึ่งเป็นหนึ่งในโปรตีนที่แสดงออกแตกต่างกันด้วยวิธี real-time RT-PCR พบว่าข้าวทรานส์เจนิกมีระดับทรานสคริปสูงกว่าข้าว wild-type การวิเคราะห์การแสดงออกร่วมชี้ให้เห็นว่ายีน LOC_Os02g11820 มีการแสดงออกร่วมเชิงบวกกับยีนสร้างเอนไซม์ peroxidase หลายยีน และมีการแสดงออกร่วมเชิงลบกับยีนสร้าง
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Woldegiorgis, S., R. C. Ahmed, Y. Zhen, C. A. Erdmann, M. L. Russell, and R. Goth-Goldstein. Genetic polymorphism in three glutathione s-transferase genes and breast cancer risk. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/799602.

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Shaw, Collin. Increased Glutathione Metabolic Defense Capabilities in Cultured Alzheimer's Diseased Lymphoblast Cell Lines. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.1702.

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Cesarini, Lucia, Flavia Grignaffini, Anna Alisi, and Anna Pastore. Alterations in glutathione redox homeostasis in metabolic dysfunction–associated fatty liver disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.10.0096.

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Zilinskas, Barbara A., Doron Holland, Yuval Eshdat, and Gozal Ben-Hayyim. Production of Stress Tolerant Plants by Overproduction of Enzymatic Oxyradical Scavengers. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568751.bard.

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Most of the objectives that were outlined in the original proposal have been met with two exceptions. Briefly, our goals were to: (1) constract transgenic tobacco plants which overproduce one or more of the enzymatic oxyradical scavengers and associated ancillary enzymes, including superoxide dismutase, ascorbate peroxidase, glutathione peroxidase, glutathione reductase, and monodehydrascorbate reductase; (2) evaluate the tolerance of these transgenic plants to oxidative stress; and (3) extend these studies to an agronomically important crop such as citrus. As can be seen i the following pages
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Diamond, A. M., J. L. Murray, P. Dale, R. Tritz, and D. J. Grdina. The effects of selenium on glutathione peroxidase activity and radioprotection in mammalian cells. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/510356.

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Mauzy, Camilla A., Nathan H. Johnson, Jason J. Jacobsen, et al. Correlation Between Iron and alpha and pi Glutathione-S-Transferase Levels in Humans. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada580919.

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Anders, M. W. Biosynthesis, Physiological Disposition, and Biochemical Effects of Nephrotoxic Glutathione and Cysteine S-Conjugates. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada221522.

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Amir, Rachel, David J. Oliver, Gad Galili, and Jacline V. Shanks. The Role of Cysteine Partitioning into Glutathione and Methionine Synthesis During Normal and Stress Conditions. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699850.bard.

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The objective of this research is to study the nature of the competition for cysteine (Cys), the first organic sulfur-containing compound, between its two main metabolites, glutathione (GSH) and methionine (Met). GSH plays a central role in protecting plants during various stresses, while Met, an essential amino acid, regulates essential processes and metabolites in plant cells through its metabolite S-adenosyl-Met. Our results, which are based on flux analysis and measurements of Met- metabolites, show that the flux towards Met synthesis is high during non-stress conditions, however the flux
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Ross, Jeffrey S. Development of an Assay for Prostate Cancer Based on Methylation Status of Glutathione S-Transferase (p). Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada395450.

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