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Rozprawy doktorskie na temat „Haemodynamics”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

O'Brien, Aoife Bernadette. "Pulmonary Haemodynamics." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398251.

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2

Leunissen, Karel Maria Lucas. "Haemodynamics during haemodialysis." Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1988. http://arno.unimaas.nl/show.cgi?fid=5410.

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3

Peacock, J. A. "Heart valve haemodynamics." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371560.

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4

Begbuna, Veronica. "Haemodynamics in chronic venous disease." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401816.

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5

Zabielski, Leszek. "Helical pipe flow in haemodynamics." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338931.

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6

Moorhead, Katherine Tracey. "Autoregulation modelling of cerebral haemodynamics." Thesis, University of Canterbury. Mechanical Engineering, 2005. http://hdl.handle.net/10092/6844.

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The Circle of Willis (CoW) is a ring-like structure of blood vessels found at the base of the brain. Its main function is to distribute a constant flow oxygen-rich arterial blood to the cerebral mass, despite changes in afferent pressures or flows. This objective is achieved by a local mechanism known as autoregulation, whereby the resistance in small vessels branching from the CoW changes by vasodilation or vasoconstriction of the smooth muscle cells surrounding the vessel. A one-dimensional (1D) model of the CoW is developed to simulate a series of possible clinical scenarios such as occlus

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7

Dalton, Matthew W. "Experimental modelling of vascular haemodynamics." Thesis, Nottingham Trent University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273762.

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8

Dury, R. J. "Understanding haemodynamics in neurodegenerative disease." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/50380/.

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In this thesis, the haemodynamic, functional and structural changes in Alzheimer's Disease, Huntington's Disease and Multiple Sclerosis are assessed at 7T. Across all chapters, there is a focus on the use of Arterial Spin Labelling (ASL) to provide haemodynamic measures of perfusion (or cerebral blood flow) and transit time (TT) to provide a useful marker of disease. Arterial Spin Labelling (ASL) has the advantage that it is a non-invasive method to measure perfusion using magnetic resonance imaging (MRI). Clinically, perfusion is assessed using contrast-enhanced techniques which requires the

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9

Williams, Stephen A. "Microvascular haemodynamics in essential hypertension." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47712.

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10

Hall, Emma Louise. "Quantitative methods to assess cerebral haemodynamics." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12673/.

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In this thesis methods for the assessment of cerebral haemodynamics using 7 T Magnetic Resonance Imaging (MRI) are described. The measurement of haemodynamic parameters, such as cerebral blood flow (CBF), is an important clinical tool. Arterial Spin Labelling (ASL) is a non-invasive technique for CBF measurement using MRI. ASL methodology for ultra high field (7 T) MRI was developed, including investigation of the optimal readout strategy. Look-Locker 3D-EPI is demonstrated to give large volume coverage improving on previous studies. Applications of methods developed to monitor functional acti

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11

Hull, James H. K. "Large artery haemodynamics in cystic fibrosis." Thesis, Kingston University, 2010. http://eprints.kingston.ac.uk/20343/.

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Cystic Fibrosis (CF) is the most common lethal autosomal recessive condition and affects approximately 1/2500 Caucasian newborns in the United Kingdom and 70,000 individuals worldwide. The gene defect classically leads to a phenotype comprising significant respiratory I and gastrointestinal manifestations, however is recognised to have multisystem consequences. Over the past 70 years there has been considerable progress in the understanding and treatment of CF such that it has moved from a poorly understood condition, almost universally fatal in infancy, to a complex multisystem disorder now a

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12

Carlisle, K. M. "Hepatic haemodynamics in health and disease." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261289.

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13

Kolachalama, Vijaya B. "Predictive haemodynamics of the human carotid artery." Thesis, University of Southampton, 2006. https://eprints.soton.ac.uk/41804/.

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This thesis employs parametrically defined geometry of the human carotid artery bifurcation to better understand the relationship between a range of parameters and the associated haemodynamics and to devise strategies to provide guidance for clinical interventions and to assist in the design of stents and grafts. Initially, detailed statistical analysis is applied to a three dimensional parametric computer aided design (CAD) model of the human carotid bifurcation. A Bayesian surrogate modelling technique is proposed and discrete locations in the CAD model are taken as random parameters to form

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14

Rowe, Christopher Stuart. "Improving the local haemodynamics of bypass graft anastomoses." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367237.

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15

Patel, Priya. "Investigation of vasomotion oscillations in spontaneous cortical haemodynamics." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/16457/.

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16

Daly, Jonathan. "Video camera monitoring to detect changes in haemodynamics." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:e84f2acf-f35c-4257-a4c3-209c5da9cbee.

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Patients in hospital can be prone to sudden, life-threatening changes in their cardiovascular state. Haemodynamic parameters such as blood pressure, pulse transit time (PTT) and perfusion can be monitored in clinical situations to identify these changes as early as possible. Continuous blood pressure is usually monitored using a catheter placed into a major artery, but this is invasive and involves risk to the patient. In the last decade, the field of non-contact vital sign monitoring has emerged, with growing evidence that the remote photoplethysmogram (rPPG) signal can be used to estimate vi

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17

Imray, Christopher H. E. "Cerebral haemodynamics in man : clinical and applied observations." Thesis, University of South Wales, 2005. https://pure.southwales.ac.uk/en/studentthesis/cerebral-haemodynamics-in-man-clinical-and-applied-observations(d355a956-a4e5-4fc3-b5ec-35e843c63402).html.

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This overview reviews seventeen publications between 1995 and 2005. CHE Imray was the first author of eleven of the papers, the senior author of four and a major contributor to two of the publications. The overview should be read in conjunction with the full copies of the seventeen publications (Appendix 2). The brain is exquisitely sensitive to oxygen requiring a constant supply of adequately oxygenated blood to function normally. Cerebral oxygen delivery is dynamic, and alters rapidly in response to changes in physiological and pathological stimuli. Interference with cerebral oxygen delivery

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18

Davies, Justin Edgar Rees. "Coronary haemodynamics in hypertension and left ventricular hypertrophy." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/7793.

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The coronary blood flow waveform is unique, being determined by simultaneous changes in pressure originating at either end of the coronary artery. However, by measuring the coronary pressure waveform alone, it is not possible to separate the pressure contributions originating from the coronary microcirculation from those originating in the aorta. In this thesis wave intensity analysis was applied to unobstructed human coronary arteries to separate the contributions originating in the coronary microcirculation from those originating in the aorta, in subjects with and without left ventricular hy

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19

Giles, Courtney. "The effects of exercise during pregnancy on haemodynamics." Phd thesis, Australian Catholic University, 2025. https://acuresearchbank.acu.edu.au/download/e5dcc5ede4572821fbb37c06a855fca2ac7c86942568f58c4f793a0579ccfc19/9449255/Giles_2025_The_effects_of_exercise_during_pregnancy.pdf.

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During pregnancy the maternal body undergoes significant physiological changes, with some of the most profound changes occurring within the cardiovascular system. Many of the cardiovascular changes occur within the first month or two of pregnancy including an increase in blood volume, cardiac output, heart rate and stroke volume, which are all associated with a decrease in vascular resistance and systemic vascular tone. Maladaptive changes to these maternal haemodynamic processes can occur during gestation, increasing the risk of gestational hypertensive conditions. Regular exercise performed

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20

Insall, R. L. "Pulse waveforms and transit time from photoelectric plethysmography in the diagnosis of peripheral vascular disease." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309069.

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21

Piechnik, Stefan K. "A mathematical and biophysical modelling of cerebral blood flow and cerebrospinal fluid dynamics." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269226.

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22

De, Villiers Anna Magdalena. "A patient-specific FSI model for vascular access in haemodialysis." Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24441.

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This research forms part of an interdisciplinary project that aims to improve the understanding of haemodynamics and vascular mechanics in arteriovenous shunting. To achieve the high flow rates that enable patients with renal disease to receive haemodialysis, a fistula is created between an artery and a vein. The patency rate of fistulas, especially those located in the upper arm, is low. The approach adopted here makes use of new magnetic resonance image (MRI) technology and computational modelling of blood flow, with a view to improving therapeutic strategies of disease requiring vascular in

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23

Frazer, Katherine H. "Computational estimation of haemodynamics and tissue stresses in abdominal." Thesis, University of Edinburgh, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491581.

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24

Whinnett, Zachary Ian. "Optimisation of cardiac resynchronisation therapy using non-invasive haemodynamics." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542962.

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25

Daub, Anna Christina [Verfasser]. "Numerical Haemodynamics in the Human Heart / Anna Christina Daub." Karlsruhe : KIT Scientific Publishing, 2018. http://www.ksp.kit.edu.

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26

Boldock, Luke. "The influence of stent geometry on haemodynamics and endothelialisation." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/19272/.

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Every year, millions of people worldwide undergo stent implantation to widen narrowed arteries or to redirect blood away from aneurysms. The rapid post-operative regrowth of a healthy endothelial layer, a key factor in stented artery repair, would reduce complications and improve quality of life for many patients. While this has long been a clinical or pharmaceutical issue, this project considers the role of local haemodynamics, specifically the effects of stent-modified wall shear stress on the endothelium. Endothelial cells have a strong mechanobiological response to wall shear stress magnit

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27

Quail, M. A. "Comprehensive assessment of vascular haemodynamics by magnetic resonance imaging." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1482118/.

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Haemodynamics is concerned with the physiological and mechanical factors that determine pressure and flow in the circulation. Currently no diagnostic modality in clinical practice provides simultaneous pressure and flow data, and therefore our analysis of fundamental haemodynamic problems is limited. Cardiac catheterisation with conventional technology can measure pressure as a function of time but can only provide estimates of mean flow. In contrast cardiac magnetic resonance imaging (CMR) can measure flow as a function of time, but cannot directly measure pressure. It is desirable that both

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28

Kirkham, Fenella Jane. "Cerebral haemodynamics in normal subjects and children in coma." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611486.

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29

Broyd, Christopher. "Coronary haemodynamics and wave intensity analysis in aortic stenosis." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/23961.

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Introduction: Coronary Wave Intensity Analysis (WIA) provides an invasive measure of energy transfer within the coronary circulation. I set out to derive a non-invasive measure of the backward expansion wave (BEW) responsible for coronary flow and assess it during exercise and in aortic stenosis (AS). Methods: 17 patients (mean age 60, 11 male) with normal cardiac function underwent invasive LAD WIA calculation using a pressure- and flow-tipped wire. Non-invasive WIA was calculated immediately after angiography from simultaneous PW Doppler of the LAD and a suprasystolic-cuff derived measure of

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30

Zhang, Kai. "Regional tissue oxygenation and haemodynamics interrogation using NIR light." Thesis, Keele University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261529.

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31

Cremona, George Ian. "Nitric oxide and pulmonary vascular resistance in health and disease." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360748.

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32

Wilson, Paul. "Computational fluid dynamic investigation of blood flow through heart valve prostheses." Thesis, Nottingham Trent University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360773.

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33

Waller, John. "Cardiovascular regulatory mechanisms in endotoxaemia." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307806.

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34

Mackin, Paul. "The effects of angiotensin-converting enzyme inhibition on glomerular morphology in acute experimental diabetes." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262885.

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35

Wesołowski, Roman. "Development of arterial spin labelling methods for monitoring cerebral haemodynamics." Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/13854/.

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The work described in this thesis was carried out at the Sir Peter Mansfield Magnetic Resonance Centre at the University of Nottingham between March 2006 and December 2009. All work described in this thesis was performed by the author, except where indicated. This thesis aims to develop and implement ASL techniques to measure haemodynamic responses to neural activity. The development of a new technique Double Acquisition Background Suppression (DABS) is presented as a remedy for a newly discovered artefact affecting Philips Achieva 7 T scanners and other sources of variation in baseline signal

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36

Hadjiloizou, Nearchos. "The effect of regional ventricular dysfunction on coronary artery haemodynamics." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516134.

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37

Ariff, Ben B. "Computational modelling of carotid artery haemodynamics in relation to atherosclerosis." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520969.

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38

Yang, Wenxuan. "A pharmacological study of hepatic haemodynamics during secondary biliary cirrhosis." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405249.

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39

McElroy, Michael. "Boundary condition assessment and geometrical accuracy enhancement for computational haemodynamics." Thesis, Manchester Metropolitan University, 2017. http://e-space.mmu.ac.uk/619019/.

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Cardiovascular diseases cause over 47 % of all deaths in Europe each year. Computational fluid dynamics provides the research community with a unique opportunity to investigate cardiovascular diseases with the intent of enabling optimised, patient-specific medical therapies. Incorporating physiologically accurate geometries and boundary conditions into computational fluid dynamics simulations can be difficult tasks and are a concern for researchers. This thesis analyses the impact various inlet and outlet boundary conditions can have on the outcome of a simulation. It also presents a novel, se

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40

Sivanesan, Sharmila. "Correlating geometry, haemodynamics and intimal hyperplasia in radiocephalic arteriovenous fistulae." Thesis, University of Liverpool, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337127.

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41

Fryer, Simon. "Physiological and psychological contributions to on-sight rock climbing, and the haemodynamic responses to sustained and intermittent contractions." Thesis, University of Canterbury. School of Sport and Physical Education, 2013. http://hdl.handle.net/10092/8704.

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Rock climbing is a multi-dimensional sport encompassing physiological, psychological, bio-mechanical and skill components. Interpretation of data in current investigations is limited by the lack of knowledge regarding the extent of the potential interaction of pre-climb anxieties with the physiological responses during an ascent. This thesis attempts to delineate the psychological and physiological contributions of on-sight top rope and lead climbing in multiple ability groups of rock climbers. Furthermore, the thesis goes on to gain an understanding of the de-oxygenation and re-oxygenation pr

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42

Cole, Jonathan Samuel. "Pulsatile, non-Newtonian blood flows through typical arterial bypass graft models." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326405.

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43

Thomas, Nicholas. "On the application of the Doppler effect in pulsed Doppler flowmeters and the effect of certain propagation and scattering artifacts." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297092.

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44

Yu, Wai-yin Alex. "Haemodynamics in dialysis hypotension and the possible role of splanchnic circulation." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36364162.

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45

Jackson, Mark John Clinical School St Vincent's Hospital Faculty of Medicine UNSW. "A study of vein graft haemodynamics using computational fluid dynamics techniques." Awarded by:University of New South Wales, 2007. http://handle.unsw.edu.au/1959.4/38575.

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Atherosclerosis, the leading cause of mortality in Western societies, affects large elastic arteries, causing focal deposition of proliferative inflammatory and lipid-laden cells within the artery. Several risk factors have been causally implicated in the ???reaction to injury??? hypothesis first described by Ross in 1969. The ???injury??? sustained by endothelial cells may be either mechanical or chemical. Environmental factors have a role in the production of chemical agents that are injurious to the endothelium. Mechanical stresses such as wall tensile stress are proportional to systemic bl

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46

Beattie, David Keith. "The influence of altered haemodynamics on human smooth muscle cell behaviour." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369122.

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47

Ngoepe, Malebogo N. "Computational modelling of thrombotic processes and complex haemodynamics in cerebral aneurysms." Thesis, University of Oxford, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639454.

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A clot in a cerebral aneurysm can either accelerate the road to rupture, through inflammatory processes and furthering vascular wall degradation, or stabilise the situation by occluding the aneurysm, and thus prevent rupture. A three-dimensional computational model of clotting in patient-derived cerebral aneurysm geometries is presented. The model accounts for the biochemical reactions that make up the clotting process, for realistic three-dimensional haemodynamics in image-derived vasculature representations and for the growing clot's interaction with and impact on the flow field. The flow is

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48

Yu, Wai-yin Alex, and 余惠賢. "Haemodynamics in dialysis hypotension and the possible role of splanchnic circulation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36364162.

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49

Fraser, Katharine H. "Computational estimation of haemodynamics and tissue stresses in abdominal aortic aneurysms." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/24588.

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Abdominal aortic aneurysm is a vascular disease involving a focal dilation of the aorta. The exact cause is unknown but possibilities include infection and weakening of the connective tissue. Risk factors include a history of atherosclerosis, current smoking and a close relative with the disease. Although abdominal aortic aneurysm can affect anyone, it is most often seen in older men, and may be present in up to 5.9% of the population aged 80 years. Biomechanical factors such as tissue stresses and shear stresses have been shown to play a part in aneurysm progression, although the specific mec

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50

Pang, Kar Lai. "The role of abnormal haemodynamics and cardiac troponin T in cardiogenesis." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39193/.

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The heart is the first functioning organ to develop during embryogenesis to maintain the growing embryo with oxygen and nutrients. However, cardiogenesis is a complex and highly coordinated biological process, and any perturbation to this process can result in detrimental defects to the heart. Haemodynamics is known to play an important role in cardiac growth and vasculature remodelling. Congenital heart defects (CHDs) accounts for 0.4-1.3% of all live birth, whereas cardiomyopathy accounts for 8-11% of cardiovascular disease diagnoses detected in utero. Although the heart defects and cardiomy

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