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Rozprawy doktorskie na temat „Heart disease”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Holt, Jim. "Heart Disease." Digital Commons @ East Tennessee State University, 2003. https://dc.etsu.edu/etsu-works/6509.

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Quigley, Gillian Margaret. "Inflammation of the heart in heart disease." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/inflammation-of-the-heart-in-heart-disease(eae19e58-aeb4-4673-924e-1dbd1c831fec).html.

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Heart failure patients have dysfunction of the cardiac conduction system that contributes to a high burden of arrhythmias including atrial fibrillation and sudden cardiac death. Heart failure has been associated with the inflammatory response, but it is unknown if inflammation is playing a role in the remodelling of the cardiac conduction system in heart failure. Inflammation has been shown to be present in the myocardium from failing hearts and it is known to have detrimental effects on cardiac function, inducing fibrosis, remodelling of ion channels and even arrhythmias. However, the effect

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3

Rix, Louise Katharine. "Biochemistry of heart disease." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334889.

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4

Misner, Scottie. "Heart Disease in Women." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 1999. http://hdl.handle.net/10150/146457.

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4 pp.<br>Heart disease, or cardiovascular disease (CVD), includes stroke and coronary heart disease, which are serious disorders of the heart and blood vessel system. Heart disease is the leading cause of illness and death in North American women. This publication addresses what kind of heart diseases affect women and how to live the heart-healthy way.

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Brown, Jessie Ann. "RUNX2 in Embryonic Heart Development and Heart Disease." Thesis, The University of Arizona, 2011. http://hdl.handle.net/10150/144250.

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6

Pratt, Rebekah Janet. "Broken hearts and the heart broken : living with, and dying from, heart failure in Scotland." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/8273.

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Heart failure is a common and serious chronic condition, which can be as ‘malignant’ as most forms of cancer (Stewart, MacIntyre, Hole, Capewell, & McMurray, 2001). Recent estimates are that around 40,000 men and 45,000 women are living with heart failure in Scotland (Stewart, MacIntyre, Capewell, & McMurray, 2003). Heart failure is significantly influenced by socioeconomic factors, with people on lower incomes being more likely to develop, and die faster from, heart failure (McAlister et al, 2004). There is a growing body of research on the experience of living with heart failure, however, no

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7

Zapanta, Laurence (Laurence F. ). "Heart rate variability in mice with coronary heart disease." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/34118.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.<br>Includes bibliographical references (leaves 69-71).<br>Heart rate variability (HRV), the beat-to-beat fluctuation of the heart rate, is a non-invasive test that measures the autonomic regulation of the heart. Assessment of HRV has been shown to predict the risk of mortality in patients after an acute myocardial infarction. Recently, the Krieger lab at MIT developed genetically engineered double knockout (dKO) mice that develop coronary artery disease accompanied by spontaneous m

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8

Field, Mark Leonard. "Biochemical basis of heart disease." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386788.

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9

Rowlinson, Giselle Victoria. "Connexins in congenital heart disease." Thesis, Imperial College London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550483.

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Gap junctions are clusters of transmembrane channels, composed of connexins (Cx), that facilitate electrical and chemical communication between the cytoplasmic compartments of contiguous cells. Three connexins are expressed in cardiac myocytes, Cx40, Cx43 and Cx45. Targeted deletion of these connexin genes in mice results in cardiac malformations and conduction abnormalities. From this background, the question arises as to whether connexins play a role in human congenital heart disease. Atrial and ventricular tissue samples were studied from patients undergoing cardiac surgery. Immunoconfocal

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10

Grech, Victor. "Congenital heart disease in Malta." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286359.

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11

Brouilette, Scott Wayne. "Telomeres and coronary heart disease." Thesis, University of Leicester, 2004. http://hdl.handle.net/2381/29899.

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Using mean telomere length as a marker of biological age, I show that: 1. Subjects with premature myocardial infarction (MI) have significantly shorter telomeres than age-sex matched, healthy, controls. The mean telomere length in MI subjects was similar to controls almost 11 years older. 2. Healthy young adult children of families with a strong history of premature MI have shorter telomeres than age matched children of families without such a history. 3. Shorter telomere lengths are associated with increase risk of subsequent CHD events in a prospective study. This analysis was carried out on

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12

Khetyar, Maher. "Genetics of congenital heart disease." Thesis, St George's, University of London, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.754064.

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Congenital Heart Disease (CHD) is the leading non-infectious cause of death among children less than one year. CHD is genetically heterogeneous, but analysis of large multi-generational families has led to the identification of a number of genes for CHD. In this project I investigated the molecular genetic basis of CHD in a large Kuwaiti family with clinically diagnosed truncus arteriosus. Using a homozygosity mapping approach I identified a region of interest on chromosome 8p21. I proceeded to sequence candidate genes in this region. One of the novel genes identified was predicted to be the h

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13

Mohamed, Kotit Susy Natalia. "Rheumatic heart disease in Egypt." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9752.

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Rheumatic Heart Disease remains one of the most neglected cardiac conditions in children and young adults around the world. The pathogenesis is complex and remains elusive, and the clinical characteristics vary around the world. This thesis concentrates on different aspects of the disease in Egypt, where it is known to have a high incidence. The methodology included epidemiological studies in school children in Aswan and investigation of RHD in a population with history of RF, using newly developed echocardiographic criteria. Concomitantly, the pattern of immune response in RF and RHD was dete

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14

Claesson, Maria. "Women's hearts : ischaemic heart disease and stress management in women." Doctoral thesis, Umeå : Department of Public Health and Clinical Medicine, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-725.

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15

Rose, Edward Leslie. "Coronary heart disease in patients with peripheral vascular disease." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305544.

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16

Heiser, Claire Anne. "Personality predictors of coronary heart disease." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/50027.

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Fifty percent of the diagnosed cases of coronary heart disease in the United States are of unknown etiology. This study proposed that five personality traits— achievement, dominance, aggression, succorance and Critical Parent—differentiate individuals with coronary heart disease manifestations. The ultimate goal of this research was to formulate a predictive profile of at-risk individuals of developing coronary heart disease. Cardiac rehabilitation units' participants from across the United States were recruited as subjects. Randomly selected cardiac rehabilitation units were sent an initial

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17

Zdravkovic, Slobodan. "Coronary heart disease in Swedish twins : quantitative genetic studies /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-771-5/.

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18

Engelman, Zoar Jacob. "Arrhythmic substrates in structural heart disease." Thesis, University of Auckland, 2011. http://hdl.handle.net/2292/9508.

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Mortality due to structural heart disease (SHD) remains high despite advances in clinical therapies. The aim of this thesis is to elucidate how structural remodeling in heart disease may lead to the development of potentially life threatening arrhythmias. This objective was advanced by the combined use of mathematical modelling and an experimental model of myocardial infarction (MI). The computer model was used to investigate possible electrical effects of tissue remodelling associated with SHD. Heterogeneous discontinuities resembling patchy fibrosis were incorporated into a 2D array o

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19

O'Sullivan, Christine Ann. "Electromechanical changes in ischaemic heart disease." Thesis, Imperial College London, 2006. http://hdl.handle.net/10044/1/8251.

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In coronary artery disease,. resting electrical and mechanical function of the left ventricle may vary according to different presentations. Stress or exercise in these patients results in electrical disturbances, which may havc mechanical consequences. The objectives ofthis thesis were: I) to assess the effect of the presence and location of Q wave myocardial infarction on left ventricular segmental mechanical function and identify patterns ofdisturbances. 2) to study the acute implications of induction of localised myocardial infarction at the proximal ventricular septum on ventricular perfo

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20

Danesh, John. "Chronic infection and coronary heart disease." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326020.

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21

Kounali, Daphne. "Early growth and coronary heart disease." Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436926.

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22

Sharma, Vishal. "Natriuretic peptides in valvular heart disease." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/23463.

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Plasma natriuretic peptide concentrations rise in response to either atrial or ventricular wall stretch and have been found to be useful in the diagnosis and assessment of patients with congestive cardiac failure. Although previous studies have suggested that plasma natriuretic peptides may offer some prognostic information in patients with valvular heart disease, it is unclear whether concentrations reflect disease severity and how plasma concentrations vary across different valve lesions. The aim of this research was to identify the factors that affect natriuretic peptide releases in valvula

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23

Taylor, Carolyn W. "Breast cancer radiotherapy and heart disease." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:c9dda3ca-8cb3-4a38-938d-0b75b4f6471d.

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Introduction: Some past breast cancer radiotherapy regimens led to an increased risk of death from heart disease. Although heart dose from breast cancer radiotherapy has generally reduced over the past few decades, there may still be some cardiac risk. Estimation of future risk for women irradiated today requires both measurement of their cardiac dose and dose-response relationships, which depend on cardiac dosimetry of past regimens, in conjunction with long-term follow-up data. Methods: Virtual simulation and computed tomography 3-dimensional treatment planning on a representative patient we

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24

Jones, David Gareth. "Interventional electrophysiology in advanced heart disease atrial fibrillation and heart failure." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/10946.

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The optimal therapy for atrial fibrillation (AF) associated with heart failure (HF) is unclear. Drug-based rhythm control has not proved clinically beneficial. Catheter ablation-based rhythm control improves cardiac function in HF patients, but impact on physiological performance has not been formally evaluated in a randomised trial. A randomised trial was designed and conducted, comparing catheter ablation with rate control in adults with symptomatic heart failure, radionuclide left ventricular ejection fraction (EF) ≤35%, and persistent AF. The primary outcome was change in peak oxygen consu

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25

Tinati, Mohammad Ali. "Time-frequency and time-scale analysis of phonocardiograms with coronary artery disease before and after angioplasty /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09pht587.pdf.

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26

Wrigley, Martha J. "Engaging families with a premature family history of heart disease : a primary prevention study for coronary heart disease." Thesis, University of Southampton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485524.

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This thesis focuses upon a preventative approach for people with a familial history of premature coronary heart disease. The research study had two aims; firstIy to understand the experience of individuals when their parent or sibling had been diagnosed with heart disease; secondly to develop and evaluate a primary prevention health promotion programme for these people. The thesis provides unique insight into their personal experiences of living with tIris familial diagnosis and gives details of how this population can be identified and involved successfully in a health promotion programme. Th

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27

Bissessor, Naylin. "Complex Heart Valve Disease: Functional Capacity and Natriuretic Peptides Predict Outcomes in mixed and Multiple Heart Valve Disease." Thesis, Griffith University, 2013. http://hdl.handle.net/10072/367217.

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Chronic mixed and multiple heart valve disease constitutes a complex group of cardiac pathologies that are prevalent world wide causing significant mortality and morbidity. The American Heart Association and the European Society of Cardiology concede in their guidelines that little data exists in the international literature on this important subject. Patients tend to adopt a sedentary lifestyle in order to cope with this illness and avoid symptoms causing a steady decline in functional capacity. A physically active lifestyle is imperative for a good quality of life and cardiovascular wellness

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28

McCafferty, Kieran. "Novel cardioprotective strategies for the uraemic heart." Thesis, Queen Mary, University of London, 2011. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8725.

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Cardiovascular disease is the leading cause of death in patients with underlying chronic kidney disease (CKD). Up to one third of patients presenting with an acute coronary syndrome have CKD stage 3-5. Outcomes following acute myocardial infarction in patients with underlying CKD remain poor. CKD patients are routinely excluded from clinical trials in novel cardioprotective strategies resulting in a paucity of prospective data on which to base guidelines for clinical practice. The aims of this work were to: • Establish and characterise two models of chronic uraemia in rodents: the subtotal nep

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29

Toren, Enoch Wolter van den. "Dihydropyridines in heart disease studies with isradipine /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 1991. http://irs.ub.rug.nl/ppn/293021511.

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30

Bagés, Nuri. "Psychosocial risk factors and coronary heart disease." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 2000. http://arno.unimaas.nl/show.cgi?fid=6899.

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31

Sartipy, Ulrik. "Left ventricular reconstruction in ischemic heart disease /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-028-2/.

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Henareh, Loghman. "Impaired glucose tolerance in ischemic heart disease /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-445-7/.

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Rydell, Karlsson Monica. "Knowledge acquisition in patients with heart disease /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-257-6/.

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34

Chandola, Tarani. "Social inequality in coronary heart disease outcomes." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285007.

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35

Abozguia, Khalid. "Metabolic alterations in patients with heart disease." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/690/.

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Despite major advances in therapies, chronic heart failure (CHF) and hypertrophic cardiomyopathy (HCM) are still associated with significant morbidity and mortality. These patients often have a significant limitation in their exercise capacity. We showed that there are widespread abnormalities of both systolic and diastolic function in HCM patients. These abnormalities contribute significantly to exercise limitation observed in these patients. Furthermore, we showed that HCM manifest a myocardial energy defieciency which was accompanied by a slowing of the energy-dependent early diastolic LV a

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36

Freitag, Daniel Franz. "Inflammatory pathways and coronary heart disease risk." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648461.

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37

Dobson, Rebecca. "Carcinoid heart disease : biochemical and echocardiographic assessment." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3003352/.

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Introduction: Carcinoid heart disease is a para-neoplastic complication of neuroendocrine tumours, occurring in patients with carcinoid syndrome. Due perhaps to its rarity, there is conflicting evidence in the literature with regard to the optimum method of diagnosis and assessment of the condition. The aim of this thesis is to quantify the variation in clinical practice with regard to carcinoid heart disease and to identify the optimum biochemical and echocardiographic methods for the screening, diagnosis and assessment of progression of the condition. Methods: Patients were prospectively rec

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38

Гордіна, Марина Андріївна, Марина Андреевна Гордина, and Maryna Andriivna Hordina. "Vitamin D deficiency and coronary heart disease." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/33551.

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Coronary heart disease (CHD) is the result of the accumulation of atheromatous plaques within the walls of the arteries that supply the myocardium with oxygen and nutrients. The WHO estimated that in 2002, 12.6% of deaths worldwide were from CHD. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/33551

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39

Springer, David Brian. "Mobile phone-based rheumatic heart disease detection." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:5ec8c818-dafb-4571-8198-97607f8d0451.

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Rheumatic heart disease (RHD), the permanent damage of the heart valves caused by an untreated 'strep throat' infection, is the leading cause of cardiovascular mortality and morbidity in children and young adults worldwide. Simple penicillin treatment after the early diagnosis of RHD can stop recurring bouts of the condition, which lead to the most severe valvulopathy, and ultimately, heart failure. However, RHD is an under-diagnosed condition in the developing world, as such a diagnosis requires, at a minimum, a trained clinician to perform auscultation to detect pathological heart sounds. Tr

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40

Kunutsor, Setor Kwadzo. "Markers of liver dysfunction and risk of coronary heart disease." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708216.

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41

Du, Ying. "Ischemic and pharmacological preconditioning of rat myocardium : effects on ischemia-reperfusion injury /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20DU.

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42

Ho, Lai-yi Ada. "Does social support influence coronary heart disease prognosis? : a meta-analysis /." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/b39724116.

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Huang, Xiao Hui. "Protective effects of sodium tanshinone II A sulfonate against sunitinib induced cardiotoxicity in H9c2 cell and zebrafish." Thesis, University of Macau, 2014. http://umaclib3.umac.mo/record=b3132193.

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44

Dorn, Karen LaVonne Toft. "Circulatory, hormonal, and metabolic effects of arbutamine compared to exercise in persons with known or suspected coronary artery disease /." This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-06062008-164634/.

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45

Liu, Jing. "Roles of heat shock protein 70 and testosterone in delayed cardioprotection of preconditioning." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37190660.

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46

Shuper, V. A. "Clinical features of chronic obstructive pulmonary disease combined with ischemic heart disease." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/17112.

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47

Savatteri, Giuseppe. "Enviromental factors influencing heart diseases." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020.

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È importante individuare strategie e meccanismi per sfruttare le opportunità offerte dalla digitalizzazione in ambito sanitario delle attività e dalla gestione dei Big Data per migliorare efficienza, monitoraggio, prevenzione e cura delle patologie. possibilità di applicazione della medicina di precisione, refertazione in anatomia patologica e automazione della raccolta dati. Il lavoro di tesi è incentrato sulle problematiche legate alle malattie cardio-cerebrovascolari e la loro correlazione con il territorio con cui i soggetti interagiscono. È stato realizzato un nuovo sistema di monitor

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48

MONTEIRO, MAYLA COSMO. "A HEART FOR TWO: THE CONGENITAL HEART DISEASE IN THE MOTHER-BABY RELATIONSHIP." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2003. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=4350@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>O presente estudo tem por objetivo a compreensão do papel da mãe na relação com o bebê cardiopata. Baseado na teoria winnicottiana, mostra ser o meio-ambiente facilitador elemento fundamental para uma relação boa o bastante ou deficitária. Para a realização da pesquisa, utilizou-se entrevistas semi-estruturadas e aplicação de desenho sobre a relação mãe-bebê. Entrevistou-se 4 mães de bebês cardiopatas, com idades de 0 a 12 meses. Os resultados revelaram temas relacionados à forma como as mães se adaptam à situação de te

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49

Cao, Fei. "Chlamydia pneumoniae, toll-like receptors and pathogenesis of atherosclerotic heart disease." View the abstract Download the full-text PDF version (on campus access only), 2007. http://etd.utmem.edu/ABSTRACTS/2007-022-Cao-index.html.

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Thesis (Ph.D. )--University of Tennessee Health Science Center, 2007.<br>Title from title page screen (viewed on May 16, 2008 ). Research advisor: Gerald I. Byrne, Ph.D. Document formatted into pages (xi, 114 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 65-107).

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Lawley, Claire Margaret. "Outcomes in structural heart disease in New South Wales, Australia: From paediatrics to pregnancy." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20465.

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Aim To characterise and explore the contemporary outcomes at key points in the life of individuals in New South Wales (NSW), Australia, who have undergone a procedure for structural heart disease. Methods The population with structural heart disease was identified and outcomes at key points in life were evaluated using different methodologies; record linkage, retrospective cohort study and systematic review. Health and education outcomes of children with structural heart disease were evaluated via population-based record-linkage cohort studies. The role of advanced imaging methods in manag

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