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Rozprawy doktorskie na temat „Human herpesviruses”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Taylor-Wiedeman, Jean. "Analysis of human cytomegalovirus in the healthy human carrier." Thesis, Open University, 1992. http://oro.open.ac.uk/57400/.

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Much circumstantial evidence has pointed to peripheral blood leukocytes as one site of persistence of Human Cytomegalovirus (HCMV) in healthy carriers. However, the exact population of peripheral blood cells that carry HCMV and to what extent they express HCMV gene products in not known. I have examined the sites of HCMV persistence in the peripheral blood of healthy carriers. Analysis of pure cell populations by the use of the polymerase chain reaction (PCR), sensitive to between 1 and 10 copies of the HCMV genome, showed that the predominant site of persistence was the monocyte. In addition,

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2

Chee, Mark. "Analysis of the human cytomegalovirus genome." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357727.

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Scholes, Andrea Gwendoline Mary. "Effect of human immunodeficiency virus infection on oral shedding of human herpesviruses." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295830.

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Vargas, Cuero Ana Laura. "Study of CD8'+T lymphocyte responses against human herpesviruses." Thesis, Open University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342897.

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5

Baker, Kevin. "Investigations into the ocular involvement of human herpes and papilloma virus infections." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266252.

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6

Enbom, Malin. "Pathogenesis of the recently identified human herpesviruses 6 and 8 /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4405-9/.

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Strand, Kurt B. "Identification of two distinct lineages of macaque gamma-2 herpesviruses /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/9309.

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NICOLI, Francesco. "Interactions between herpesviruses and the human immune system in old age." Doctoral thesis, Università degli studi di Ferrara, 2022. http://hdl.handle.net/11392/2481326.

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Il processo di invecchiamento è accompagnato da un declino delle funzioni immunitarie che può svolgere un ruolo importante nella bassa efficacia delle vaccinazioni nelle persone anziane. Tuttavia, non è chiaro se esista una cooperazione fra meccanismi intrinseci legati all'età e fattori esterni (come le infezioni con virus persistenti) nella progressione dell'immunosenescenza. Lo scopo di questo lavoro è di studiare l'interazione tra il sistema immunitario dell'ospite e 3 principali herpesvirus (HSV-1, CMV ed EBV). Per raggiungere questo scopo, mi sono concentrato prima sull'effetto delle in

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9

Lepper, Mark William. "Immune modulation by human cytomegalovirus following reactivation in immunocompromised patients." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324251.

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Fok, Yuen-kei Vivien. "Expression of human herpesvirus 6 (HHV-6) genes in virus-infected cells /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31385515.

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Fok, Yuen-kei Vivien, and 霍沅琪. "Expression of human herpesvirus 6 (HHV-6) genes in virus-infected cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45010006.

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Li, Ying Ting. "Role of the human β-herpesviruses in organ allograft rejection following transplantation". Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444976/.

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In previous prospective studies conducted in our department, PCR was used to detect the three β-herpesviruses, human cytomegalovirus (HCMV), and human herpesviruses 6 and 7 (HHV-6 and HHV-7) in the blood of solid organ transplant patients. The viruses were commonly detected post-transplantation, and HCMV and HHV-6 were independently associated with graft rejection in liver recipients. HHV-7 was also associated with increased episodes of rejection in renal transplant patients. To better understand the role of these viruses in graft rejection, in situ techniques including in situ hybridisation (

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13

Massaro, Raffaele <1988&gt. "Interaction of Glycoproteins H/L from human α-herpesviruses with αvβ integrins". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7967/1/raffaele_massaro_tesi.pdf.

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Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV) belong to the viral subfamily Alphaherpesvirinae, and are important neurotropic human pathogens. HSV and VZV fuse their envelope with the membrane of the host cell, a process termed cell entry, accomplished by a conserved trio of viral glycoproteins (gB, gH and gL). Host cell receptors mediate viral entry, i.e. nectin1 is recognized by the viral tropism factor gD in HSV, while the host receptor is still elusive in VZV. Integrins are widely distributed adhesion membrane proteins, and give critical contribution to the entry of most huma

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14

Lübke, Maren [Verfasser]. "Mapping of the cytotoxic T cell response against two human herpesviruses / Maren Lübke." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1218073144/34.

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15

Arbuckle, Jesse Herbert. "Identification and Characterization of the Human Herpesviruses 6A and 6B Genome Integration into Telomeres of Human Chromosomes during Latency." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/2989.

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While the latent genome of most Herpesviruses persists as a nuclear circular episome, previous research has suggested that Human Herpesvirus 6 (HHV-6) may integrate into host cell chromosomes, and be vertically transmitted in the germ-line. Because the HHV-6 genome encodes a perfect TTAGGG telomere repeat array at the right end direct repeat (DRR) and an imperfect TTAGGG repeat at the end of the left end direct repeat (DRL), we established a hypothesis that during latency, the HHV-6A and HHV-6B genome integrates into the telomeres of human chromosomes through homologous recombination with the

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16

Gwela, Agnes A. "Analysis of the immune evasion mechanisms of varicella zoster virus." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:79814bbd-ed0a-47b4-9894-96710892eefa.

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Varicella zoster virus (VZV) is an alpha herpes virus that causes primary infection with varicella (chicken pox), establishes latency in ganglia and may later reactivate as herpes zoster (shingles). Innate immune effectors are thought to control initial viral replication, but it is the adaptive immune system, involving T cells that mediates eventual control of viraemia and the associated clinical disease. Although both CD4<sup>+</sup> and CD8<sup>+</sup> T cells mediate viral clearance during acute illness, memory responses are dominated by CD4<sup>+</sup> T cells. We tested the hypothesis tha

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17

Eleuterio, Junior Jose. "Marcadores biomoleculares de lesões epiteliais escamosas genitais pre-invasivas." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309413.

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Orientador: Paulo Cesar Giraldo<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-08T21:42:54Z (GMT). No. of bitstreams: 1 EleuterioJunior_Jose_D.pdf: 17867889 bytes, checksum: 0d9e1c3f2399c5be86d6fbf719dc98c4 (MD5) Previous issue date: 2007<br>Resumo: Objetivos: Estudar a importância de determinados marcadores de diagnóstico e prognóstico de lesões escamosas genitais, com ênfase nos estudos de p16INK4a e HPV de alto risco. Material e Métodos: Marcadores tumorais foram revisados em 21 estudos publicados entre 1994 e

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18

Kidd, Ian Michael. "Human cytomegalovirus, human herpesvirus 6 and human herpesvirus 7 infection of the immunocompromised host." Thesis, University College London (University of London), 1997. http://discovery.ucl.ac.uk/1453654/.

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19

Costa, Victor Bernardes Barroso. "Investigação da presença e da influência do Epstein-Barr vírus na severidade da papilomatose laríngea /." São José dos Campos, 2019. http://hdl.handle.net/11449/180669.

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Orientador: Estela Kaminagakura<br>Coorientadora: Patrícia Pimentel de Barros<br>Banca: Ana Sueli Rodrigues Cavalcant<br>Banca: Luana Marotta Reis de Vasconcellos<br>Banca: Lia Mizobe Ono<br>Banca: Luciana Yamamoto de Almeida<br>Resumo: A papilomatose laríngea é uma neoplasia benigna causada pelo papilomavírus humano (HPV), sendo os tipos 6 e 11 os mais comuns, e que ocorre em dois grupos etários, juvenil e adulto. A possível coinfecção viral tem sido sugerida em lesões de cabeça e pescoço; nesse sentido, o Epstein Barr vírus (EBV), que também apresenta tropismo por células epiteliais vem send

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20

Elzinger, Bianca Ariane. "Studies on a new human herpesvirus, Kaposi's sarcoma-associated herpesvirus." Thesis, University College London (University of London), 2000. http://discovery.ucl.ac.uk/1318064/.

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Kaposi's sarcoma (KS)-associated herpesvirus (KSHV), also called human herpesvirus 8 (HHV8), has been been identified in all epidemiological forms of KS as well as in tissue obtained from primary effusion lymphoma (PEL) and Multicentric Castleman's disease (MCD). The KSHV genome contains several putative oncogenes, suggesting that viral infection may induce cellular transformation and tumorgenesis. Herpesviruses encode a number of different surface glycoproteins, which are involved in virus-host interactions. Studies have shown that the viral glycoproteins H and L form a complex that plays an

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21

Thomasini, Ronaldo Luís 1978. "Citomegalovírus, herpesvírus humano 6, herpesvírus humano 7 e perfil imunofenotípico do infiltrado inflamatório na periodontite crônica marginal." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311940.

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Orientador: Sandra Cecília Botelho Costa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-19T10:22:52Z (GMT). No. of bitstreams: 1 Thomasini_RonaldoLuis_D.pdf: 2991233 bytes, checksum: 570abfb75508069faffb192f2c6c5dcd (MD5) Previous issue date: 2011<br>Resumo: Periodontite humana crônica é um processo inflamatório caracterizado por denso acúmulo de células imunes no tecido periodontal. A periodontite pode levar a perda do dente no paciente e a patogênese desta doença não é completamente conhecida. Este estudo testou

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22

Polstra, Abeltje Mette. "Human herpesvirus 8: virology and disease." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/74171.

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23

Silva, Ana Carolina Guardia da 1980. "Avaliação da cinética viral do Herpesvirus Humano 6 e Citomegalovirus por PCR em tempo real e das complicações clínicas relacionadas ocorridas após o transplante de fígado." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309659.

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Orientadores: Ilka de Fatima Santana Ferreira Boin, Raquel Silveira Bello Stucchi<br>Tese (doutorador) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-24T02:50:29Z (GMT). No. of bitstreams: 1 Silva_AnaCarolinaGuardiada_D.pdf: 4973684 bytes, checksum: b2c754b94b99a119ae7e84ac207a9555 (MD5) Previous issue date: 2013<br>Resumo: Introdução: As infecções oportunistas constituem um dos principais problemas para os transplantados de fígado. O Citomegalovírus (CMV) e o Herpesvirus humano 6 (HHV- 6) são patógenos oportunistas freqüentes nesses

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24

Yoshikawa, Tetsushi. "Human herpesvirus 6 iInfection in transplantation." Nagoya University School of Medicine, 2001. http://hdl.handle.net/2237/5363.

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Parola, Daniela Corte. "Herpesvirus humano 5,6 e 7 (HHV-5, HHV-6 e HHV-7) em receptores de transplantes de medula ossea." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311928.

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Orientador: Sandra Cecilia Botelho Costa<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-09T12:05:48Z (GMT). No. of bitstreams: 1 Parola_DanielaCorte_M.pdf: 2987280 bytes, checksum: 06dcaf150379c56fac854a42d4bc3453 (MD5) Previous issue date: 2007<br>Resumo: O membro protótipo da subfamília dos betaherpesvírus, o citomegalovírus humano (HCMV), é o patógeno mais importante em pacientes transplantados, incluindo aqueles que receberam células de medula óssea ou enxerto de células tronco. Testes diagnósticos para

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26

Chagas, Cristiano Aparecido. "Pesquisa do herpesvirus tipo 8 (HHV8) em adenoides e tonsilas de crianças : um estudo imunoistoquimico e por hibridização "in situ"." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310138.

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Orientador: Jose Vassallo<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-06T13:44:11Z (GMT). No. of bitstreams: 1 Chagas_CristianoAparecido_D.pdf: 2698514 bytes, checksum: 839362fd3abba979b5a2b1472c7865a6 (MD5) Previous issue date: 2006<br>Resumo: Contexto: o herpesvírus humano tipo 8 (HHV8) foi recentemente associado a neoplasias humanas, como o sarcoma de Kaposi e o linfoma não Hodgkin de células B das cavidades serosas em pacientes infectados pelo vírus da imunodeficiência humana (HIV), além da doença de Castle

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Kaye, Jane Frances. "Studies of human cytomegalovirus glycoproteins." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259731.

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Ng, Hoi-yee Iris, and 吳凱怡. "Human herpesvirus 6 (HHV-6) mRNA in peripheral blood leukocytes differentiates active infection from latency." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31226589.

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Ng, Hoi-yee Iris. "Human herpesvirus 6 (HHV-6) mRNA in peripheral blood leukocytes differentiates active infection from latency /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B24520895.

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Pasquotto, Juliana. "Detecção e quantificação do virus Epstein-Barr pela reação em cadeia da polimerase em tempo real (real time PCR) em pacientes transplantados de celulas hematopoeticas e coinfecção com o citomegalovirus." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311920.

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Orientador: Sandra Cecilia Botelho Costa<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-11T03:22:40Z (GMT). No. of bitstreams: 1 Pasquotto_Juliana_M.pdf: 2465167 bytes, checksum: dcd2cc122494bab62d8ab495927b1f0e (MD5) Previous issue date: 2008<br>Resumo: O Vírus Epstein-Barr (EBV) e o Citomegalovírus (HCMV) são membros da família Herpesvírus. São encontrados em aproximadamente 90% dos indivíduos em idade adulta. A infecção ocorre, geralmente, na infância e é assintomática na maioria dos casos, persistindo de

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Bianchi, Bianca Real 1987. "Estudo da atividade anti-herpética de isolados de organismos marinhos." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308719.

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Orientadores: Clarice Weis Arns, Luciana Konecny Kohn<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T23:34:00Z (GMT). No. of bitstreams: 1 Bianchi_BiancaReal_M.pdf: 1619930 bytes, checksum: 92df5dc0e4cba5e4314f506e39ff0be1 (MD5) Previous issue date: 2012<br>Resumo: O vírus herpes simples do tipo 1 (HSV-1), agente etiológico do herpes labial em humanos, é facilmente transmitido e têm o grande problema de causar infecções latentes, sendo que uma vez infectado, o indivíduo passa a ser o portador do vírus por

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Milan, Arlete 1972. "Correlação do citomegalovírus e do Herpesvírus Humano 8 nas infecções bacterianas em pacientes submetidos a transplante de fígado." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311662.

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Orientadores: Raquel Silveira Bello Stucchi, Sandra Cecília Botelho Costa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-23T21:51:59Z (GMT). No. of bitstreams: 1 Milan_Arlete_D.pdf: 3275520 bytes, checksum: 25bbae8b034967286ca090efbc210090 (MD5) Previous issue date: 2013<br>Resumo: O transplante de fígado tornou-se a terapia mais eficaz para o tratamento dos pacientes com doença hepática terminal, sendo que o sucesso pode ser limitado por complicações infecciosas no primeiro ano pós-transplante. O citomegalovírus

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Di, Alberti Luca. "Human herpesvirus 8 and new pathological associations." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300031.

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34

Tweedy, Joshua. "Genomic characterisation of chromosomally integrated human herpesvirus." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2016. http://researchonline.lshtm.ac.uk/2544332/.

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Distinctions in the biological features of human herpesvirus-6A (HHV-6A) and -6B (HHV-6B) have recently led to their reclassification from variants to distinct viral species. Unique for human herpesviruses, these viruses also exist in an endogenous form in ~1% of the human population, resulting from germ-line chromosomal integration. Chromosomally integrated human herpesvirus-6A (CI-HHV-6A) and -6B (CI-HHV-6B) genomes are inherited in a Mendelian manner, leading to the potential for viral gene expression and/or reactivation in every cell of the body. As yet, the effects of these integrated vir

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35

Minton, Elizabeth Jane. "Infection of the monocytic cell lineage by human cytomegalovirus." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315286.

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Nowak, Monika. "Human herpesvirus-6-induced cytokines and lymphocyte anergy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0009/NQ28364.pdf.

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Lawrence, Glenda L. "Sequence analysis of the human herpesvirus-6 genome." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386182.

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Beyari, Mohammed Mustafa. "Multiple infection by human herpesvirus-8 and cytomegalovirus." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444349/.

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To substantiate the hypothesis that multiple infection by human herpesvirus 8 (HHV-8) and by cytomegalovirus (CMV) commonly occurs, intraperson nucleotide variation in DNA amplified from hypervariable subgenomic domains of HHV-8 and CMV was evaluated in a group of people living in Malawi, where both viruses circulate hyperendemically. Mouth rinses, throat gargles, palatal exfoliates and blood were sampled from 89 people (age range: 4 m to 45 y). In 24 people (27%), HHV-8 DNA could be amplified in >1 sample 9 (38%) were seropositive for human immunodeficiency virus-1 and 7 (29%) exhibited Kapos

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Whitby, Denise. "Human herpesvirus 8 (HHV-8) and Kaposi's sarcoma." Thesis, Institute of Cancer Research (University Of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368195.

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Thomasini, Ronaldo Luís 1978. "Detecção e monitorização do Herpesvirus humano 7 (HHV-7) em transplantados hepaticos : impacto clinico e associação com Citomegalovirus e Herpesvirus humano 6." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311931.

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Orientador: Sandra Cecilia Botelho Costa<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-08T20:07:57Z (GMT). No. of bitstreams: 1 Thomasini_RonaldoLuis_M.pdf: 1552471 bytes, checksum: 69e020e777011a1dab1c773d2466694a (MD5) Previous issue date: 2007<br>Resumo: Neste estudo, 29 pacientes adultos, transplantados de fígado foram monitorados (até 180 dias pós-transplante) para infecções ativas por HCMV, HHV-6 e HHV-7 usando Nested-PCR (N-PCR). O protocolo de imunossupressão foi baseado na combinação de esteróides

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Wang, Fu-Zhang. "Human herpesvirus 6 infection after allogeneic stem cell transplantation /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3589-0/.

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Kubo, Toru. "Human immune responses against Kaposi's Sarcoma-associated Herpesvirus (KSHV)." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429041.

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Hughes, R. "Herpesvirus and HIV-1 co-infection of human macrophages." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1563691/.

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HSV-1 and HIV-1 co-infection of human macrophages represents a clinically relevant model with which to investigate the host-pathogen interactions between macrophages and viruses. In this thesis, I demonstrate that HSV-1 productively infects human monocyte derived macrophages, with associated cell death and type I IFN responses, and additionally, that a proportion of macrophages support latent HSV-1 infection. I de ne latency as the absence of lytic gene transcription, virion production and cell death, in the presence of persistent expression of the HSV-1 latency associated transcript (LAT). I

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Bell, Adam Joseph. "Inherited chromosomally integrated human herpesvirus 6 : demographics and disease." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7073/.

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Human herpesvirus (HHV) –6A and HHV-6B are unique among herpesviruses in their ability to integrate into the telomeres of human chromosomes and be inherited in a Mendelian fashion. Based on current data, inherited chromosomally integrated HHV-6 (iciHHV-6) is present in 0.5-2% of the UK population. There is increasing evidence to suggest that iciHHV-6 is not a dead-end for the virus, and that HHV-6 can be excised from the genomes of iciHHV-6-positive individuals. It is hypothesised that this excision occurs from the formation of T-loops between the end of the telomere and the viral telomere lik

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Mendonça, Regina Maria Holanda de. "Associação entre a presença de microoganismos da microbiota oral e a intensidade da mucosite oral, em pacientes pediatricos com leucemia linfoide aguda, submetidos ao tratamento antineoplasico." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312074.

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Orientador: Silvia Regina Brandalise<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-11T14:31:49Z (GMT). No. of bitstreams: 1 Mendonca_ReginaMariaHolandade_D.pdf: 3329753 bytes, checksum: 332276846d50abe7bcfd9a72c1a6bb9c (MD5) Previous issue date: 2008<br>Resumo: Introdução: Dentre os efeitos secundários à quimioterapia, a mucosite oral é um dos mais freqüentes. Entre os fatores que contribuem para esta susceptibilidade estão a alta taxa de renovação celular e a presença dos microorganismos, que encontram na cavida

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Faro, Eduardo Salustino. "Epidemiologia molecular do herpesvírus humano tipo 6 (HHV-6) em crianças recém-nascidas e suas respectivas mães." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-06012009-162645/.

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A infecção primária com o herpesvirus humano tipo 6 (HHV-6) pode resultar no exantema súbito, encefalite e recorrentes complicações. Pesquisas demonstram que crianças obtêm os anticorpos contra o HHV-6 antes dos dois anos de idade. Após a infecção primária, o DNA do HHV-6 permanece latente em linfócitos, saliva ou líquor. A rota de transmissão permanece controversa. A liberação do HHV-6 em saliva parece ser a maior rota de transmissão. A transmissão intra-uterina, integrada no cromossomo é outra sugestão de transmissão. Foram colhidas 172 amostras, 86 de secreção cervical (mãe) e 86 de aspirad

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Palmieri, Michelle. "Detecção dos herpesvirus humanos na mucosa oral de pacientes irradiados para tratamento de carcinoma epidermoide em região de cabeça e pescoço." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/23/23141/tde-24052016-173046/.

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A radioterapia para tratamento das neoplasias malignas em região de cabeça e pescoço é acompanhada de diversas complicações, decorrentes do comprometimento dos tecidos radiossensíveis localizados próximos ao tumor. Entre essas complicações a mucosite é a que merece maior destaque. A mucosite é uma reação tóxica inflamatória da mucosa oral causada pelo tratamento citorredutivo induzido pela radioterapia (RT) ou pela quimioterapia (QT). Ela manifesta-se com sinais de edema, eritema, úlcera e formação pseudomembrana, resultando em sintomas de ardência, que pode progredir para dor intensa e conseq

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Iglesias, J. Gerardo. "Studies on the vertical transmission of Suid herpesvirus-1 in pigs." Thesis, University of Surrey, 1985. http://epubs.surrey.ac.uk/847553/.

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Vertical transmission of Aujeszky's Disease virus (ADV) was studied in pigs with two British strains. The strains used were both isolated from an outbreak of disease in Yorkshire. In vivo experiments involving intranasal infection of 10-week old pigs revealed that one strain was highly virulent (Leeds-1) while the other was of low virulence (Leeds-2). Both experimental and natural infections were evaluated by the clinical response and by the detection of specific immune responses. The techniques used included class-specific ELISA tests, lymphocyte transformation and antibody-dependent cellular

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Wallaschek, Nina [Verfasser]. "Role of the herpesvirus telomeric repeats and the protein U94 in human herpesvirus 6 integration / Nina Wallaschek." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/110293318X/34.

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Yazbek, Michel Alexandre 1978. "Associação do Epstein-Barr vírus com os anticorpos anti-CCP, os alelos do epítopo compartilhado e o tabagismo em pacientes brasileiros com artrite reumatoide." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310635.

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Orientadores: Manoel Barros Bértolo, Lilian Tereza Lavras Costallat<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-26T07:51:21Z (GMT). No. of bitstreams: 1 Yazbek_MichelAlexandre_D.pdf: 3193834 bytes, checksum: 4155cea9577385c29405700add4864ef (MD5) Previous issue date: 2014<br>Resumo: A etiopatogenia da Artrite Reumatoide (AR) envolve fatores genéticos, imunológicos e ambientais que interagem entre si. Os principais fatores de risco estudados são a presença dos alelos do epítopo compartilhado (shared epitope- SE)

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