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1

Voropaev, E. V. "MOLECULAR AND GENETIC FACTORS FOR REALIZATION OF THE PATHOGENIC POTENTIAL OF <i>HELICOBACTER PYLORI:</i> PERSONIFIED TECHNIQUES FOR ASSESSMENT OF MANIFESTATIONS, LABORATORY DIAGNOSIS AND PROGNOSIS." Health and Ecology Issues, no. 1 (March 28, 2018): 15–20. http://dx.doi.org/10.51523/2708-6011.2018-15-1-3.

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The work presents an analytical review of features of techniques for assessment of the pathogenetic potential of Helicobacter pylori bacterium, an etiological agent of a number of gastrointestinal diseases. The main emphasis is laid on modern molecular and genetic techniques that make it possible to assess not only the pathogenic potential of the bacterium, but also the characteristics of the stomach microbiota and the infected human host`s genotype.
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Johnsborg, Ola, and Leiv Sigve Håvarstein. "Pneumococcal LytR, a Protein from the LytR-CpsA-Psr Family, Is Essential for Normal Septum Formation in Streptococcus pneumoniae." Journal of Bacteriology 191, no. 18 (2009): 5859–64. http://dx.doi.org/10.1128/jb.00724-09.

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ABSTRACT Proliferation of the human-pathogenic bacterium Streptococcus pneumoniae is fundamentally linked to the bacterial proteins that function in cell division. Here, we show that LytR, a pneumococcal protein from the LytR-CpsA-Psr family, is essential to this process.
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Gerrard, John G., Nicholas R. Waterfield, and Maria Sanchez-Contreeras. "Photorhabdus asymbiotica: Shedding Light on a Human Pathogenic Bioluminescent Bacterium." Clinical Microbiology Newsletter 33, no. 14 (2011): 103–9. http://dx.doi.org/10.1016/j.clinmicnews.2011.06.004.

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Kumar, Rajneesh, and Pooja Singh. "Characterization and Diagnostics of Listeria Monocytogenes: A Human Pathogen." Asian Pacific Journal of Health Sciences 9, no. 2 (2022): 102–8. http://dx.doi.org/10.21276/apjhs.2022.9.2.21.

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Listeria monocytogenes, Gram positive bacteria, rod-shaped, intracellular, opportunistic, invasive food borne bacterium, which is ubiquitous in nature. Soil, vegetation, sewage, water, and fecal materials are its primary source through which it reaches to our food system. It is one of the leading food borne bacteria which is pathogenic, causing Listeriosis in immunodeficient children, adult, pregnant women, central nervous system infection, bacteremia, and other clinical manifestation. Bacterium has arsenal of virulence factors Listeriolysin, phospholipases, internalins and Act A protein which
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Martins, Rodrigo, Cristiana Mateus, Fernanda Domingues, Roland Bücker, Mónica Oleastro, and Susana Ferreira. "Effect of Atmospheric Conditions on Pathogenic Phenotypes of Arcobacter butzleri." Microorganisms 10, no. 12 (2022): 2409. http://dx.doi.org/10.3390/microorganisms10122409.

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Arcobacter butzleri is an emergent gram-negative enteropathogenic bacterium widespread in different environments and hosts. During the colonization of the gastrointestinal tract, bacteria face a variety of environmental conditions to successfully establish infection in a new host. One of these challenges is the fluctuation of oxygen concentrations encountered not only throughout the host gastrointestinal tract and defences but also in the food industry. Oxygen fluctuations can lead to modulations in the virulence of the bacterium and possibly increase its pathogenic potential. In this sense, e
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Oliver, J. D., D. M. Roberts, V. K. White, M. A. Dry, and L. M. Simpson. "Bioluminescence in a strain of the human pathogenic bacterium Vibrio vulnificus." Applied and Environmental Microbiology 52, no. 5 (1986): 1209–11. http://dx.doi.org/10.1128/aem.52.5.1209-1211.1986.

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Pozdeev, О. К., А. О. Pozdeeva, Yu V. Valeeva, and P. E. Gulyaev. "MECHANISMS OF INTERRACTION OF HELICOBACTER PYLORI WITH EPITHELIUM OF GASTRIC MUCOSA. I. PATHOGENIC FACTORS PROMOTING SUCCESSFUL COLONIZATION." Russian Journal of Infection and Immunity 8, no. 3 (2018): 273–83. http://dx.doi.org/10.15789/2220-7619-2018-3-273-283.

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H. pylori is a Gram-negative, crimp and motile bacterium that colonizes the hostile microniche of the human stomach roughly one half of the human population. Then persists for the host’s entire life, but only causes overt gastric disease in a subset of infected hosts. To the reasons contributing to the development of diseases, usually include: concomitant infections of the gastrointestinal tract, improper sterilization of medical instruments, usually endoscopes, nonobservance of personal hygiene rules, prolonged contact with infected or carriers, including family members and a number of other
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Spigaglia, Patrizia, Fabrizio Barbanti, and Paola Mastrantonio. "Tetracycline Resistance Gene tet(W) in the Pathogenic Bacterium Clostridium difficile." Antimicrobial Agents and Chemotherapy 52, no. 2 (2007): 770–73. http://dx.doi.org/10.1128/aac.00957-07.

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ABSTRACT In this study, the tet(W) gene region of a human clinical isolate of Clostridium difficile resistant to tetracycline was characterized. This gene was a new allele showing 99% sequence identity to the gene found in the human strain Bifidobacterium longum F8, and it is not transferable by “in vitro” mating experiments.
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Tran, Tran Thi Ai, You Jung Kang, Hyun-Kyoung Kim, Hyung-Ryong Kim, and Hansang Cho. "Oral Pathogenic Bacteria-Inducing Neurodegenerative Microgliosis in Human Neural Cell Platform." International Journal of Molecular Sciences 22, no. 13 (2021): 6925. http://dx.doi.org/10.3390/ijms22136925.

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Porphyromonas gingivalis is a gram-negative bacterium found in the human oral cavity and is responsible for the development of chronic periodontitis as well as neurological diseases, including Alzheimer’s disease (AD). Given the significance of the roles of P. gingivalis in AD pathogenesis, it is critical to understand the underlying mechanisms of P. gingivalis-driven neuroinflammation and their contribution to neurodegeneration. Herein, we hypothesize that P. gingivalis produces secondary metabolites that may cause neurodegeneration through direct or indirect pathways mediated by microglia. T
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10

Kim, Kwang Kyu, Keun Chul Lee, Haeyoung Jeong, David A. Stevens, and Jung-Sook Lee. "Draft Genome Sequence of the Human Pathogen Halomonas stevensii S18214T." Journal of Bacteriology 194, no. 18 (2012): 5143. http://dx.doi.org/10.1128/jb.01071-12.

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ABSTRACTHalomonas stevensiiis a Gram-negative, moderately halophilic bacterium causing environmental contamination and infections in a dialysis center. Here we present the 3.7-Mb draft genome sequence of the type strain (S18214T) ofH. stevensii, which will give insight into the pathogenic potential ofH. stevensii.
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11

Patel, B. H., M. Z. Channiwala, S. B. Chaudhari, and A. A. Mandot. "Biosynthesis of copper nanoparticles; its characterization and efficacy against human pathogenic bacterium." Journal of Environmental Chemical Engineering 4, no. 2 (2016): 2163–69. http://dx.doi.org/10.1016/j.jece.2016.03.046.

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Bleakley, Bruce H., and Xiang Chen. "Survival of insect pathogenic and human clinical isolates ofPhotorhabdus luminescensin previously sterile soil." Canadian Journal of Microbiology 45, no. 3 (1999): 273–78. http://dx.doi.org/10.1139/w98-231.

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Most characterized strains of the bacterium Photorhabdus luminescens are symbionts of entomopathogenic nematodes, whereas other strains have been isolated from human clinical specimens. The ability of P. luminescens strains to survive and grow in soil has received limited attention, with some studies indicating these bacteria have little or no ability to persist in soil. Survival and (or) growth of P. luminescens strains in previously sterilized soil, and examination of different soil amendments on their numbers in soil, have not been previously reported. Entomopathogenic P. luminescens (ATCC
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13

Wan, Shan, Min Xia, Jie Tao, et al. "Metagenomics Analysis Reveals the Microbial Communities, Antimicrobial Resistance Gene Diversity and Potential Pathogen Transmission Risk of Two Different Landfills in China." Diversity 13, no. 6 (2021): 230. http://dx.doi.org/10.3390/d13060230.

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In this study, we used a metagenomic approach to analyze microbial communities, antibiotic resistance gene diversity, and human pathogenic bacterium composition in two typical landfills in China. Results showed that the phyla Proteobacteria, Bacteroidetes, and Actinobacteria were predominant in the two landfills, and archaea and fungi were also detected. The genera Methanoculleus, Lysobacter, and Pseudomonas were predominantly present in all samples. sul2, sul1, tetX, and adeF were the four most abundant antibiotic resistance genes. Sixty-nine bacterial pathogens were identified from the two l
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14

Li, Z., H. Chen, X. Chen, et al. "Genome Sequence of the Human-Pathogenic Bacterium Vibrio vulnificus Type Strain ATCC 27562." Journal of Bacteriology 195, no. 7 (2013): 1622. http://dx.doi.org/10.1128/jb.00067-13.

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Li, Z., H. Chen, X. Chen, et al. "Genome Sequence of the Human-Pathogenic Bacterium Vibrio vulnificus Type Strain ATCC 27562." Journal of Bacteriology 194, no. 24 (2012): 6954–55. http://dx.doi.org/10.1128/jb.01890-12.

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Greenberg, David E., Stephen F. Porcella, Adrian M. Zelazny, et al. "Genome Sequence Analysis of the Emerging Human Pathogenic Acetic Acid Bacterium Granulibacter bethesdensis." Journal of Bacteriology 189, no. 23 (2007): 8727–36. http://dx.doi.org/10.1128/jb.00793-07.

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ABSTRACT Chronic granulomatous disease (CGD) is an inherited immune deficiency characterized by increased susceptibility to infection with Staphylococcus, certain gram-negative bacteria, and fungi. Granulibacter bethesdensis, a newly described genus and species within the family Acetobacteraceae, was recently isolated from four CGD patients residing in geographically distinct locales who presented with fever and lymphadenitis. We sequenced the genome of the reference strain of Granulibacter bethesdensis, which was isolated from lymph nodes of the original patient. The genome contains 2,708,355
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17

Vasse, Marie, Robert J. Noble, Andrei R. Akhmetzhanov, et al. "Antibiotic stress selects against cooperation in the pathogenic bacterium Pseudomonas aeruginosa." Proceedings of the National Academy of Sciences 114, no. 3 (2017): 546–51. http://dx.doi.org/10.1073/pnas.1612522114.

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Cheats are a pervasive threat to public goods production in natural and human communities, as they benefit from the commons without contributing to it. Although ecological antagonisms such as predation, parasitism, competition, and abiotic environmental stress play key roles in shaping population biology, it is unknown how such stresses generally affect the ability of cheats to undermine cooperation. We used theory and experiments to address this question in the pathogenic bacterium, Pseudomonas aeruginosa. Although public goods producers were selected against in all populations, our competiti
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18

Nelson, Karen E., Robert D. Fleischmann, Robert T. DeBoy, et al. "Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83." Journal of Bacteriology 185, no. 18 (2003): 5591–601. http://dx.doi.org/10.1128/jb.185.18.5591-5601.2003.

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ABSTRACT The complete 2,343,479-bp genome sequence of the gram-negative, pathogenic oral bacterium Porphyromonas gingivalis strain W83, a major contributor to periodontal disease, was determined. Whole-genome comparative analysis with other available complete genome sequences confirms the close relationship between the Cytophaga-Flavobacteria-Bacteroides (CFB) phylum and the green-sulfur bacteria. Within the CFB phyla, the genomes most similar to that of P. gingivalis are those of Bacteroides thetaiotaomicron and B. fragilis. Outside of the CFB phyla the most similar genome to P. gingivalis is
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19

Young, J. M., C. Allen, T. Coutinho, et al. "Plant-Pathogenic Bacteria as Biological Weapons – Real Threats?" Phytopathology® 98, no. 10 (2008): 1060–65. http://dx.doi.org/10.1094/phyto-98-10-1060.

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At present, much attention is being given to the potential of plant pathogens, including plant-pathogenic bacteria, as biological weapons/bioterror weapons. These two terms are sometimes used interchangeably and there is need for care in their application. It has been claimed that clandestine introduction of certain plant-pathogenic bacteria could cause such crop losses as to impact so significantly on a national economy and thus constitute a threat to national security. As a separate outcome, it is suggested that they could cause serious public alarm, perhaps constituting a source of terror.
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Mardaneh, Jalal. "Cronobacter Sakazakii: A Foodborne Pathogenic Bacterium in Immunocompromised and Hospitalized Patients." Quarterly of the Horizon of Medical Sciences 27, no. 2 (2021): 264–87. http://dx.doi.org/10.32598/hms.27.2.1402.4.

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Aims: Cronobacter sakazakii (CS) is a member of the Enterobacteriaceae family. It is a genomically heterogeneous, motile, Gram-negative bacillus. It is also an emergent foodborne pathogen associated with the ingestion of infant formula milk that can cause neonatal sepsis, necrotizing enterocolitis, and meningitis. This review is focused on the newest information about the bacterial characteristics of C. sakazakii and human infections causing by this pathogenic bacterium. Methods &amp; Materials: We searched medical databases such as ISI Web of Science, PubMed, Scopus, and other websites. Findi
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Toh, Hidehiro, Kenshiro Oshima, Atsushi Toyoda, et al. "Complete Genome Sequence of the Wild-Type Commensal Escherichia coli Strain SE15, Belonging to Phylogenetic Group B2." Journal of Bacteriology 192, no. 4 (2009): 1165–66. http://dx.doi.org/10.1128/jb.01543-09.

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ABSTRACT Escherichia coli SE15 (O150:H5) is a human commensal bacterium recently isolated from feces of a healthy adult and classified into E. coli phylogenetic group B2, which includes the majority of extraintestinal pathogenic E. coli. Here, we report the finished and annotated genome sequence of this organism.
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Saran, Anshu, Nuwani Weerasinghe, Christopher J. Thibodeaux, and Natalie Zeytuni. "Purification, crystallization and crystallographic analysis of the PorX response regulator associated with the type IX secretion system." Acta Crystallographica Section F Structural Biology Communications 78, no. 10 (2022): 354–62. http://dx.doi.org/10.1107/s2053230x22008500.

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Pathogenic bacteria utilize specialized macromolecular secretion systems to transport virulence factors across membrane(s) and manipulate their infected host. To date, 11 secretion systems have been identified, including the type IX secretion system (T9SS) associated with human, avian and farmed-fish diseases. As a bacterial secretion system, the T9SS also facilitates gliding motility and the degradation of different macromolecules by the secretion of metabolic enzymes in nonpathogenic bacteria. PorX is a highly conserved protein that regulates the transcription of essential T9SS components an
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Adams, Felise G. "A key regulatory mechanism of antimicrobial resistance in pathogenic Acinetobacter baumannii." Microbiology Australia 38, no. 3 (2017): 122. http://dx.doi.org/10.1071/ma17046.

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Acinetobacter baumannii is a Gram-negative bacterial pathogen that has become a pressing global health issue in recent decades. Although virulence factors for this pathogen have been identified, details of how they are regulated are largely unknown. One widely employed regulatory mechanism that bacteria, such as A. baumannii, have adopted is through two component signal transduction systems (TCS). TCS consist of two proteins; a histidine kinase and response regulator. The histidine kinase allows the bacterium to sense alterations in the extracellular milieu, transmitting the information to the
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Rahmati Holasoo, Hooman, Iradj Ashrafi Tamai, Wolfram Manuel Brück, Babak Pakbin, Alireza Nasiri, and Amirparsa Azizi. "Morganella Morganii Infection in Hirudo Medicinalis (Iran): A Case Report." Veterinary Sciences 9, no. 10 (2022): 562. http://dx.doi.org/10.3390/vetsci9100562.

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Medicinal leeches (Hirudo medicinalis) are used in surgical and non-surgical manners. Morganella morganii is an opportunistic and zoonotic pathogenic bacterium causing serious clinical complications. In this study, we isolated, discovered and characterized M. morganii-infected H. medicinalis. We detected and identified M. morganii in all inflamed and swollen Hirudo medicinalis samples. The 16S rRNA sequence of the isolates confirmed all strains of M. morganii. All strains were sensitive to Ceftriaxone, Ceftiofur, Danofloxacin, Ciprofloxacin, Enrofloxacin, Oxytetracycline, and Meropenem and wer
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Petrzik, Karel, Sára Brázdová, and Krzysztof Krawczyk. "Novel Viruses That Lyse Plant and Human Strains of Kosakonia cowanii." Viruses 13, no. 8 (2021): 1418. http://dx.doi.org/10.3390/v13081418.

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Kosakonia cowanii (syn. Enterobacter cowanii) is a highly competitive bacterium that lives with plant, insect, fish, bird, and human organisms. It is pathogenic on some plants and an opportunistic pathogen of human. Nine novel viruses that lyse plant pathogenic strains and/or human strains of K. cowanii were isolated, sequenced, and characterized. Kc166A is a novel kayfunavirus, Kc261 is a novel bonnellvirus, and Kc318 is a new cronosvirus (all Autographiviridae). Kc237 is a new sortsnevirus, but Kc166B and Kc283 are members of new genera within Podoviridae. Kc304 is a new winklervirus, and Kc
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Swolana, Denis, and Robert D. Wojtyczka. "Activity of Silver Nanoparticles against Staphylococcus spp." International Journal of Molecular Sciences 23, no. 8 (2022): 4298. http://dx.doi.org/10.3390/ijms23084298.

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Staphylococcus epidermidis is a bacterium that is part of the human microbiota. It is most abundant on the skin, in the respiratory system and in the human digestive tract. Also, Staphylococcus aureus contributes to human infections and has a high mortality rate. Both of these bacterial species produce biofilm, a pathogenic factor increasing their resistance to antibiotics. For this reason, we are looking for new substances that can neutralize bacterial cells. One of the best-known substances with such effects are silver nanoparticles. They exhibited antibacterial and antibiofilm formation act
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Kohli, Vandita, Ramasubramanian Vaidhyanathan, Amjad K. Balange, Binaya Bhusan Nayak, and Sanath H. Kumar. "Distribution of Vibrio parahaemolyticus in Farmed Shrimp Penaeus vannamei, Farm Water and Sediment." Journal of Pure and Applied Microbiology 15, no. 3 (2021): 1608–16. http://dx.doi.org/10.22207/jpam.15.3.57.

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The halophilic marine bacterium Vibrio parahaemolyticus is a zoonotic pathogen associated with wild-caught and farmed shrimp. The bacterium is an important cause of gastroenteritis associated with the consumption of raw or undercooked seafood. In the present study, the prevalence and human pathogenic potential of Vibrio parahaemolyticus in Penaeus vannamei (tissue and hepatopancreas) and the farm environment (water and sediment) was investigated by conventional culture and molecular techniques. The total Vibrio counts of P. vannamei ranged from &lt;1 CFU/mL in hemolymph to 7.61 log CFU/g in th
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Vale, Filipa F., António P. A. Matos, Patrícia Carvalho, and Jorge M. B. Vítor. "Helicobacter pylori Phage Screening." Microscopy and Microanalysis 14, S3 (2008): 150–51. http://dx.doi.org/10.1017/s1431927608089721.

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Helicobacter pylori is a helical shaped Gram-negative bacterium that colonizes the human stomach. It is associated with several human pathologies, such as gastritis, peptic ulcer, and gastric cancer. The standard first-line treatment is a one week triple therapy: the association of two antibiotics, most frequently amoxicillin and clarithromycin, and a proton pump inhibior. Despite the evolution of the treatment strategy, quadruple therapy, there is an increasing percentage of failure of the antibiotic therapy, due to antibiotics resistance. Phage therapy is the therapeutic use of lytic bacteri
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Maier, R. J. "Use of molecular hydrogen as an energy substrate by human pathogenic bacteria." Biochemical Society Transactions 33, no. 1 (2005): 83–85. http://dx.doi.org/10.1042/bst0330083.

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Molecular hydrogen is produced as a fermentation by-product in the large intestine of animals and its production can be correlated with the digestibility of the carbohydrates consumed. Pathogenic Helicobacter species (Helicobacter pylori and H. hepaticus) have the ability to use H2 through a respiratory hydrogenase, and it was demonstrated that the gas is present in the tissues colonized by these pathogens (the stomach and the liver respectively of live animals). Mutant strains of H. pylori unable to use H2 are deficient in colonizing mice compared with the parent strain. On the basis of avail
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Cong, Xiaomei, Shuang Zhao, Qing Zhang, Shuo Liu, Youming Zhang, and Fu Yan. "Isolation, Characterization, and Genome Engineering of a Lytic Pseudomonas aeruginosa Phage." Microorganisms 12, no. 11 (2024): 2346. http://dx.doi.org/10.3390/microorganisms12112346.

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Antibiotic-resistant bacterial infections have become one of the leading causes of human mortality. Bacteriophages presented great potential for combating antibiotic-resistant infections in the post-antibiotic era due to their high host specificity and safety profile. Pseudomonas aeruginosa, an opportunistic pathogenic bacterium, has shown a surge in multidrug-resistant strains, severely impacting both human health and livestock. In this study, we successfully isolated and purified a P. aeruginosa-specific phage, PpY1, from feces collected from a breeding farm. This phage harbors a short tail
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Singh, Balvindra, Neelam Singh, and Raghuvendra Singh. "Isolated of Staphylococcus and gram-negative bacteria from the hospitalized area and screening bacteria against various plant extract." International Journal Of Medical Science And Clinical Invention 5, no. 3 (2018): 3619–24. http://dx.doi.org/10.18535/ijmsci/v5i3.12.

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Staphylococcus aureus is a bacterium that is a member of the Firmicutes and is frequently found in the human respiratory tract and on the skin. Although S. aureus is not always pathogenic, it is a common cause of skin infections (e.g. boils), respiratory disease (e.g. sinusitis), and food poisoning. Disease-associated strains often promote infections by producing potent protein toxins and expressing cell-surface proteins that bind and inactivate antibodies. The emergence of antibiotic-resistant forms of pathogenic S. aureus (e.g. MRSA) is a worldwide problem in clinical medicine.
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Charoenlap, Nisanart, Zeli Shen, Megan E. McBee, et al. "Alkyl Hydroperoxide Reductase Is Required for Helicobacter cinaedi Intestinal Colonization and Survival under Oxidative Stress in BALB/c and BALB/c Interleukin-10−/−Mice." Infection and Immunity 80, no. 3 (2011): 921–28. http://dx.doi.org/10.1128/iai.05477-11.

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Helicobacter cinaedi, a common human intestinal bacterium, has been implicated in various enteric and systemic diseases in normal and immunocompromised patients. Protection against oxidative stress is a crucial component of bacterium-host interactions. Alkyl hydroperoxide reductase C (AhpC) is an enzyme responsible for detoxification of peroxides and is important in protection from peroxide-induced stress.H. cinaedipossesses a singleahpC, which was investigated with respect to its role in bacterial survival during oxidative stress. TheH. cinaedi ahpCmutant had diminished resistance to organic
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Hao, Mingyue, Minghui Wang, Ting Tang, et al. "Regulation of the Gene for Alanine Racemase Modulates Amino Acid Metabolism with Consequent Alterations in Cell Wall Properties and Adhesive Capability in Brucella spp." International Journal of Molecular Sciences 24, no. 22 (2023): 16145. http://dx.doi.org/10.3390/ijms242216145.

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Brucella, a zoonotic facultative intracellular pathogenic bacterium, poses a significant threat both to human health and to the development of the livestock industry. Alanine racemase (Alr), the enzyme responsible for alanine racemization, plays a pivotal role in regulating virulence in this bacterium. Moreover, Brucella mutants with alr gene deletions (Δalr) exhibit potential as vaccine candidates. However, the mechanisms that underlie the detrimental effects of alr knockouts on Brucella pathogenicity remain elusive. Here, initially, we conducted a bioinformatics analysis of Alr, which demons
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Kawakita, Yoshito, Miki Kinoshita, Yukio Furukawa, et al. "Structural Study of MPN387, an Essential Protein for Gliding Motility of a Human-Pathogenic Bacterium, Mycoplasma pneumoniae." Journal of Bacteriology 198, no. 17 (2016): 2352–59. http://dx.doi.org/10.1128/jb.00160-16.

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ABSTRACTMycoplasma pneumoniaeis a human pathogen that glides on host cell surfaces with repeated catch and release of sialylated oligosaccharides. At a pole, this organism forms a protrusion called the attachment organelle, which is composed of surface structures, including P1 adhesin and the internal core structure. The core structure can be divided into three parts, the terminal button, paired plates, and bowl complex, aligned in that order from the front end of the protrusion. To elucidate the gliding mechanism, we focused on MPN387, a component protein of the bowl complex which is essentia
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AUDISIO, M. CARINA, GUILLERMO OLIVER, and MARÍA C. APELLA. "Antagonistic Effect of Enterococcus faecium J96 against Human and Poultry Pathogenic Salmonella spp." Journal of Food Protection 62, no. 7 (1999): 751–55. http://dx.doi.org/10.4315/0362-028x-62.7.751.

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Production of antagonistic compounds was studied in a strain of Enterococcus faecium isolated from the intestinal tract of a free-ranging chicken. Production of lactic acid and a bacteriocin was observed in cultures of this bacterium, alone and in mixed culture fermentations with pathogenic Salmonella serotypes (i.e., Gallinarum, Pullorum, Enteritidis, and Typhimurium). Growth inhibition of these avian and human pathogens was observed after 4 h of incubation at 37°C in CAm broth, a medium developed according to the nutrients present in chicken food. The antibacterial action was due to the comb
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Pereira, Raquel M. M., Hugo V. C. Oliveira, Suanni L. Andrade, Elliot W. Kitajima, and Rudi E. L. Procopio. "Isolation of a Mycobacteriophage against Mycobacterium smegmatis." European Journal of Biology and Biotechnology 2, no. 1 (2021): 34–37. http://dx.doi.org/10.24018/ejbio.2021.2.1.147.

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The Mycobacterium genus has important pathogenic species, such as M. leprae and M. tuberculosis, with high incidence in the human population. The number of bacterial strains resistant to antibiotics is steadily increasing, and in particular no new antibiotics have been developed for Mycobacterium. Mycobacteriophages have been shown to be viable alternatives, mainly to counteract antibiotic-resistant bacteria. A new mycobacteriophage (Myms-1) was isolated from sewage in Manaus, Amazonas state, Brazil, with lytic activity against M. smegmatis. Morphological analysis of the Mysm-1 phage shows tha
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., K. U. Desai, and B. H. Patel . "Bio-Burden Test: New Approach to Evaluate Efficacy of Corporate Uniform against Human Pathogenic Bacterium." Journal of Current Pharma Research 5, no. 4 (2015): 1647–53. http://dx.doi.org/10.33786/jcpr.2015.v05i04.008.

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Del Prete, Sonia, Viviana De Luca, Andrea Scozzafava, Vincenzo Carginale, Claudiu T. Supuran та Clemente Capasso. "Biochemical properties of a new α-carbonic anhydrase from the human pathogenic bacterium, Vibrio cholerae". Journal of Enzyme Inhibition and Medicinal Chemistry 29, № 1 (2013): 23–27. http://dx.doi.org/10.3109/14756366.2012.747197.

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Han, Cong, Qi Wang, Lei Dong, et al. "Molecular cloning and characterization of a new peptide deformylase from human pathogenic bacterium Helicobacter pylori." Biochemical and Biophysical Research Communications 319, no. 4 (2004): 1292–98. http://dx.doi.org/10.1016/j.bbrc.2004.05.120.

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Nadarasah, Geetanchaly, and John Stavrinides. "Quantitative evaluation of the host-colonizing capabilities of the enteric bacterium Pantoea using plant and insect hosts." Microbiology 160, no. 3 (2014): 602–15. http://dx.doi.org/10.1099/mic.0.073452-0.

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The genus Pantoea is a highly diverse group comprising free-living, and both pathogenic and non-pathogenic host-associating species. Pathogenic isolates have been found to infect insects, plants and humans, yet it is unclear whether these isolates have similar pathogenic potential to the free-living environmental populations. Using MLSA of six housekeeping genes, we evaluated the phylogenetic relationships among 115 environmental and clinical (human) isolates representing 11 Pantoea species. An overlay of the location of isolation onto the resulting tree revealed that clinical and environmenta
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Naidoo, Natalie, and Oliver T. Zishiri. "Presence, Pathogenicity, Antibiotic Resistance, and Virulence Factors of Escherichia coli: A Review." Bacteria 4, no. 1 (2025): 16. https://doi.org/10.3390/bacteria4010016.

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Escherichia coli (E. coli) is a Gram-negative, commensal/pathogenic bacteria found in human intestines and the natural environment. Pathogenic E. coli is known as extra-intestinal pathogenic E. coli (ExPEC) or intestinal pathogenic E. coli (InPEC). InPEC E. coli strains are separated into six pathogenic groups, known as enteropathogenic (EPEC), enterotoxigenic (ETEC), enteroinvasive (EIEC), enteroaggregative (EAEC), enterohaemorrhagic (EHEC), and diffusely adherent (DAEC), that have various virulence factors that cause infection. Virulence factors refer to a combination of distinctive accessor
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Nikolic, Philip, and Poonam Mudgil. "The Cell Wall, Cell Membrane and Virulence Factors of Staphylococcus aureus and Their Role in Antibiotic Resistance." Microorganisms 11, no. 2 (2023): 259. http://dx.doi.org/10.3390/microorganisms11020259.

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Antibiotic resistant strains of bacteria are a serious threat to human health. With increasing antibiotic resistance in common human pathogens, fewer antibiotics remain effective against infectious diseases. Staphylococcus aureus is a pathogenic bacterium of particular concern to human health as it has developed resistance to many of the currently used antibiotics leaving very few remaining as effective treatment. Alternatives to conventional antibiotics are needed for treating resistant bacterial infections. A deeper understanding of the cellular characteristics of resistant bacteria beyond w
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Kraaijvanger, Raisa, and Marcel Veltkamp. "The Role of Cutibacterium acnes in Sarcoidosis: From Antigen to Treatable Trait?" Microorganisms 10, no. 8 (2022): 1649. http://dx.doi.org/10.3390/microorganisms10081649.

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Cutibacterium acnes (C. acnes, formerly Propionibacterium acnes) is considered to be a non-pathogenic resident of the human skin, as well as mucosal surfaces. However, it also has been demonstrated that C. acnes plays a pathogenic role in diseases such as acne vulgaris or implant infections after orthopedic surgery. Besides a role in infectious disease, this bacterium also seems to harbor immunomodulatory effects demonstrated by studies using C. acnes to enhance anti-tumor activity in various cancers or vaccination response. Sarcoidosis is a systemic inflammatory disorder of unknown causes. Cu
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Purohit, Ritu, and Shouriehebal Soni. "Isolation and Identification of Vibrio sp. from Marine Fishes of Mumbai, Maharashtra, India." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 15 (2024): 179–87. http://dx.doi.org/10.56557/upjoz/2024/v45i154233.

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Vibrio is a common bacterium found in marine fishes. Vibrio species are pathogenic to humans and cause various gastrointestinal diseases. Fish markets, fish harvesting areas, vectors like flies, seawater and sometimes fresh water bodies are the source of spread of this bacterium. Improper handling or pathogen contamination during transit has an impact not only on human health but also on the population of marine fish. Vibrio is known to be a human pathogen, the onset and spread of this bacterium causes severe diarrhoea. In this study, the presence of Vibrio species in marine water fishes was d
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Hu, Yuanyuan, Ge Liu, Chaomin Sun, and Shimei Wu. "Volatile Organic Compounds Produced by a Deep-Sea Bacterium Efficiently Inhibit the Growth of Pseudomonas aeruginosa PAO1." Marine Drugs 22, no. 5 (2024): 233. http://dx.doi.org/10.3390/md22050233.

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The deep-sea bacterium Spongiibacter nanhainus CSC3.9 has significant inhibitory effects on agricultural pathogenic fungi and human pathogenic bacteria, especially Pseudomonas aeruginosa, the notorious multidrug-resistant pathogen affecting human public health. We demonstrate that the corresponding antibacterial agents against P. aeruginosa PAO1 are volatile organic compounds (VOCs, namely VOC-3.9). Our findings show that VOC-3.9 leads to the abnormal cell division of P. aeruginosa PAO1 by disordering the expression of several essential division proteins associated with septal peptidoglycan sy
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Huq, Mohsina, Syeda Umme Habiba Wahid, and Taghrid Istivan. "Biofilm Formation in Campylobacter concisus: The Role of the luxS Gene." Microorganisms 12, no. 1 (2023): 46. http://dx.doi.org/10.3390/microorganisms12010046.

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Campylobacter concisus is a bacterium that inhabits human oral cavities and is an emerging intestinal tract pathogen known to be a biofilm producer and one of the bacterial species found in dental plaque. In this study, biofilms of oral and intestinal C. concisus isolates were phenotypically characterized. The role of the luxS gene, which is linked to the regulation of biofilm formation in other pathogens, was assessed in relation to the pathogenic potential of this bacterium. Biofilm formation capacity was assessed using phenotypic assays. Oral strains were shown to be the highest producers.
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Novinscak, A., M. Filion, C. Surette, and C. Allain. "Application of molecular technologies to monitor the microbial content of biosolids and composted biosolids." Water Science and Technology 57, no. 4 (2008): 471–77. http://dx.doi.org/10.2166/wst.2008.019.

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Disposal of human biosolids is a source of concern for public health and the environment. Composting appears to be an interesting alternative to traditional disposal methods as it can decrease the load of human pathogenic microorganisms often present in biosolids and yield an end-product rich in nutrients for use as a soil supplement. Assessing the exact microbial content of biosolids, both for biosafety and operational reasons, has traditionally relied on the use of standard microbiological methods. Recent developments in molecular-based technologies now offer more rapid and specific monitori
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Wang, Rongzhi, Sui Fang, Dinglong Wu, et al. "Screening for a Single-Chain Variable-Fragment Antibody That Can Effectively Neutralize the Cytotoxicity of the Vibrio parahaemolyticus Thermolabile Hemolysin." Applied and Environmental Microbiology 78, no. 14 (2012): 4967–75. http://dx.doi.org/10.1128/aem.00435-12.

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ABSTRACTVibrio parahaemolyticusis a halophilic bacterium that is widely distributed in water resources. The bacterium causes lethal food-borne diseases and poses a serious threat to human and animal health all over the world. The major pathogenic factor ofV. parahaemolyticusis thermolabile hemolysin (TLH), encoded by thetlhgene, but its toxicity mechanisms are unknown. A high-affinity antibody that can neutralize TLH activity effectively is not available. In this study, we successfully expressed and purified the TLH antigen and discovered a high-affinity antibody to TLH, named scFv-LA3, by pha
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Young, Vincent B. "Old and new models for studying host-microbe interactions in health and disease:C. difficileas an example." American Journal of Physiology-Gastrointestinal and Liver Physiology 312, no. 6 (2017): G623—G627. http://dx.doi.org/10.1152/ajpgi.00341.2016.

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There has been an explosion of interest in studying the indigenous microbiota, which plays an important role in human health and disease. Traditionally, the study of microbes in relationship to human health involved consideration of individual microbial species that caused classical infectious diseases. With the interest in the human microbiome, an appreciation of the influence that complex communities of microbes can have on their environment has developed. When considering either individual pathogenic microbes or a symbiotic microbial community, researchers have employed a variety of model s
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Schouler, Catherine, Ahmed Taki, Iman Chouikha, Maryvonne Moulin-Schouleur, and Philippe Gilot. "A Genomic Island of an Extraintestinal Pathogenic Escherichia coli Strain Enables the Metabolism of Fructooligosaccharides, Which Improves Intestinal Colonization." Journal of Bacteriology 191, no. 1 (2008): 388–93. http://dx.doi.org/10.1128/jb.01052-08.

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ABSTRACT Prebiotics such as fructooligosaccharides (FOS) are increasingly being used in some countries for improving human and animal health and as an alternative to antibiotic growth promoters in animals, with various degrees of success. It has been observed that FOS stimulate the proliferation of probiotic bacteria and, at the same time, decrease the population of bacteria associated with disease. This observation assumes that pathogenic bacteria do not metabolize FOS and, therefore, lose their competitive advantage over beneficial bacteria. Here we present evidence that some pathogenic Esch
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