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Artykuły w czasopismach na temat „Human reproductive technology. Fertilization in vitro, Human”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 2 lutego 2022

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Deep, JP. "Assisted Reproductive Technology." Journal of Chitwan Medical College 4, no. 1 (2014): 1–10. http://dx.doi.org/10.3126/jcmc.v4i1.10840.

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All the treatment or procedure that includes the handling of both human sperm and oocytes or embryos in vitro for the purpose of establishing a pregnancy in order to bypass some pathological obstacles in human reproduction is known as Assisted Reproductive Technology (ART). Now we must be approaching 1.5 million Assisted Reproductive Technology birth since the birth of the world’s first in vitro fertilization baby, Louise Brown, in the United Kingdom. The infertility is caused by various reason and factors from either or both partners. Infertility affects worldwide by 8-15 percent of couples i

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Sherwin, Susan. "Feminist Ethics and In Vitro Fertilization." Canadian Journal of Philosophy Supplementary Volume 13 (1987): 264–84. http://dx.doi.org/10.1080/00455091.1987.10715938.

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New technology in human reproduction has provoked wide ranging arguments about the desirability and moral justifiability of many of these efforts. Authors of biomedical ethics have ventured into the field to offer the insight of moral theory to these complex moral problems of contemporary life. I believe, however, that the moral theories most widely endorsed today are problematic and that a new approach to ethics is necessary if we are to address the concerns and perspectives identified by feminist theorists in our considerations of such topics. Hence, I propose to look at one particular techn

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Lam, Carla. "Thinking Through Post-constructionism: Reflections on (Reproductive) Disembodiment and Misfits." Studies in Social Justice 10, no. 2 (2016): 289–307. http://dx.doi.org/10.26522/ssj.v10i2.1352.

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In this article, I draw together feminist research on the distinct areas of assisted human reproduction (or new reproductive technology) and post-constructionist theory to examine some common methodological and epistemological issues fundamental for reproductive justice. I revisit the notion of technologically-assisted (reproductive) disembodiment (e.g., in vitro fertilization, surrogacy and egg donation) in light of theoretical developments in feminism, in particular post-constructionism. Specifically, I ask what light is shed on the paradox of reproduction (in particular disembodied reproduc

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Menezo, Yves, Patrice Clément, and Brian Dale. "DNA Methylation Patterns in the Early Human Embryo and the Epigenetic/Imprinting Problems: A Plea for a More Careful Approach to Human Assisted Reproductive Technology (ART)." International Journal of Molecular Sciences 20, no. 6 (2019): 1342. http://dx.doi.org/10.3390/ijms20061342.

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An increasing number of publications indicate that babies born after IVF (in vitro fertilization) procedures have higher rates of anomalies related to imprinting/epigenetic changes, which may be attributed to suboptimal culture conditions. Appropriate maintenance of DNA methylation during the first few days of an in vitro culture requires a supply of methyl donors, which are lacking in current in vitro culture systems. The absence of protection against oxidative stress in the culture increases the risks for errors in methylation. A decrease in the methylation processes is sometimes observed im

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Rajinikanthan, DB Usha, and Thankam Varma. "Comparison of in vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Patients receiving Recombinant Human Luteinizing Hormone vs Human Menopausal Gonadotropin Supplementation." International Journal of Infertility & Fetal Medicine 7, no. 3 (2016): 77–81. http://dx.doi.org/10.5005/jp-journals-10016-1133.

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ABSTRACT Objectives To compare the outcome of recombinant human luteinizing hormone (rh-LH) and human menopausal gonadotropin (hMG) supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with recombinant follicle stimulating hormone (FSH) in the long gonadotropinreleasing hormone (GnRH) agonist stimulation protocol. Materials and methods It was a retrospective analysis of the case records of 90 consecutive women who underwent nondonor IVF/ICSI cycle with long GnRH agonist. All women received recombinant FSH on day 2/3 of the programming cycle. W

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Manzoor, Asma, and Saba Imran Ali. "Horrors Of Baby Making (Consequences Of Reproductive Technology On Humanity)." Pakistan Journal of Gender Studies 1, no. 1 (2008): 1–9. http://dx.doi.org/10.46568/pjgs.v1i1.251.

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The recent advances in the field of medical sciences have allowed the scientists to control the processes of life and death. These processes not only can prolong the human life by machines but doctors and scientists can also initiate the process of human life: artificial insemination, cloning, in vitro fertilization (IVF), cyropreservation of sperm, oocytes, embryos, embryo transfer (ET), hormone treatment, surrogacy, testicular sperm extraction (TESE) and gamete intra fallopian transfer (GIFT) are well known examples. By far the most common of these is IVF. As a result of these scientific inn

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Wilcox, Allen J., Quaker Harmon, Kevin Doody, Don P. Wolf, and Eli Y. Adashi. "Preimplantation loss of fertilized human ova: estimating the unobservable." Human Reproduction 35, no. 4 (2020): 743–50. http://dx.doi.org/10.1093/humrep/deaa048.

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Abstract STUDY QUESTION What proportion of fertilized human ova are lost before implantation? SUMMARY ANSWER An estimated 40 to 50% of fertilized ova fail to implant. WHAT IS KNOWN ALREADY Preimplantation loss is not detectable with current technology. Published estimates of preimplantation loss range from 10 to 70%. STUDY DESIGN, SIZE, DURATION We combine data from epidemiologic, demographic, laboratory and in vitro fertilization studies to construct an empirical framework for the estimation of preimplantation loss. This framework is summarized in a user-friendly Excel file included in supple

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Robertson, John A., and Theodore J. Schneyer. "Professional Self-Regulation and Shared-Risk Programs for In Vitro Fertilization." Journal of Law, Medicine & Ethics 25, no. 4 (1997): 283–91. http://dx.doi.org/10.1111/j.1748-720x.1997.tb01410.x.

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In vitro fertilization (IVF) is now a well-established practice in the field of assisted reproduction. In 1995, over 41,000 IVF cycles were done in the United States, at a cost of more than $300 million. The overall success rate has risen to 22.8 deliveries per 100 egg-retrieval procedures (19.6 deliveries per initiated cycle). As the field has matured, the attention of policy-makers has shifted from questions about the ethical and legal status of human embryos to concerns about providing access and protecting consumers.Three such concerns have emerged. One is the danger that IVF programs will

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Tamura, Hiroshi, Mai Jozaki, Manabu Tanabe, et al. "Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging." International Journal of Molecular Sciences 21, no. 3 (2020): 1135. http://dx.doi.org/10.3390/ijms21031135.

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Melatonin is probably produced in all cells but is only secreted by the pineal gland. The pineal secretion of melatonin is determined by the light–dark cycle, and it is only released at night. Melatonin regulates biological rhythms via its receptors located in the suprachiasmatic nuclei of the hypothalamus. Melatonin also has strong antioxidant activities to scavenge free radicals such as reactive oxygen species (ROS). The direct free radical scavenging actions are receptor independent. ROS play an important role in reproductive function including in the ovulatory process. However, excessive R

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Tilly, Jonathan L., and Dori C. Woods. "The obligate need for accuracy in reporting preclinical studies relevant to clinical trials: autologous germline mitochondrial supplementation for assisted human reproduction as a case study." Therapeutic Advances in Reproductive Health 14 (January 2020): 263349412091735. http://dx.doi.org/10.1177/2633494120917350.

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A now large body of work has solidified the central role that mitochondria play in oocyte development, fertilization, and embryogenesis. From these studies, a new technology termed autologous germline mitochondrial energy transfer was developed for improving pregnancy success rates in assisted reproduction. Unlike prior clinical studies that relied on the use of donor, or nonautologous, mitochondria for microinjection into eggs of women with a history of repeated in vitro fertilization failure to enhance pregnancy success, autologous germline mitochondrial energy transfer uses autologous mitoc

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Jones-Nosacek, Cynthia. "Fertility Technology Research and the Use of Human Beings as Property." Linacre Quarterly 87, no. 4 (2020): 376–80. http://dx.doi.org/10.1177/0024363920947263.

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In January 2020, an article in the Journal of Human Reproduction exploring whether human embryos could be obtained via uterine lavage and to compare their quality to embryos created via in vitro fertilization. Any embryo that was not removed via lavage was either prevented from implanting by giving the women injections of gonadotropin releasing hormone antagonists or aborted with either methotrexate or uterine curettage. This research was done using women in Mexico, who were paid the equivalent of over two months’ wages and who signed away their rights to their embryos, including agreeing to h

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Polotsky, Alex, and Jasmine Aly. "Paternal Diet and Obesity: Effects on Reproduction." Seminars in Reproductive Medicine 35, no. 04 (2017): 313–17. http://dx.doi.org/10.1055/s-0037-1602593.

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AbstractAlthough most research has focused on maternal obesity, there is growing data to indicate that obesity in the father can affect reproduction. Supporting data come from both mouse and human studies. Murine studies found that obese male mice exhibited decreased motility and reduced hyperactivated progression versus lean mice. Obese mice also exhibited sperm with increased levels of intracellular and mitochondrial levels of reactive oxygen species, increased sperm damage, and lower levels of capacitation, which has been shown to be associated with poor fertilization rates following in vit

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Crockin, Susan L., Delia Ribas, Gerardo Escalante, Lauren Nussbaum, and Howard W. Jones. "Costa Rica's absolute ban on in vitro fertilization deemed a human rights violation: implications for U.S. assisted reproductive technology policy and “personhood” initiatives." Fertility and Sterility 100, no. 2 (2013): 330–33. http://dx.doi.org/10.1016/j.fertnstert.2013.04.025.

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Tanaka, Atsushi, Motoi Nagayoshi, Youichi Takemoto, et al. "Fourteen babies born after round spermatid injection into human oocytes." Proceedings of the National Academy of Sciences 112, no. 47 (2015): 14629–34. http://dx.doi.org/10.1073/pnas.1517466112.

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During the human in vitro fertilization procedure in the assisted reproductive technology, intracytoplasmic sperm injection is routinely used to inject a spermatozoon or a less mature elongating spermatid into the oocyte. In some infertile men, round spermatids (haploid male germ cells that have completed meiosis) are the most mature cells visible during testicular biopsy. The microsurgical injection of a round spermatid into an oocyte as a substitute is commonly referred to as round spermatid injection (ROSI). Currently, human ROSI is considered a very inefficient procedure and of no clinical

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Heinzmann, J., T. Hansmann, C. Wrenzycki, U. Zechner, T. Haaf, and H. Niemann. "261 INFLUENCE OF IN VITRO MATURATION ON EPIGENETIC MARKS AND GENE EXPRESSION IN BOVINE OOCYTES." Reproduction, Fertility and Development 23, no. 1 (2011): 228. http://dx.doi.org/10.1071/rdv23n1ab261.

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In cattle, in vitro maturation (IVM) of oocytes is an integral part of assisted reproduction technology. However, only 30% of in vitro matured bovine oocytes develop to the blastocyst stage after fertilization (compared with 60% for in vivo matured oocytes), indicating critical involvement of maturation conditions in the developmental competence of oocytes. Oocytes for IVF and intracytoplasmic sperm injection in humans are typically allowed to mature in vivo after superovulation because IVM is not considered to be a safe medical procedure. Several studies have shown that assisted reproduction

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Vukosavljevic, Jelena, Aleksandra Trninic-Pjevic, Artur Bjelica, Ivana Jagodic, Vesna Kopitovic, and Stevan Milatovic. "Detection of human embryo aneuploidy in the procedure of in vitro fertilization after preimplantation genetic screening using array comparative genomic hybridization." Medical review 70, no. 9-10 (2017): 325–31. http://dx.doi.org/10.2298/mpns1710325v.

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Introduction. Numerical aberrations (whole chromosomal aneuploidy) have been considered one of the most important factors leading to implantation failure and early miscarriages in patients undergoing assisted reproductive procedures. Embryo selection is mainly based on morphological assessment; however, embryos produced from aneuploid gametes cannot be distinguished from euploid based on morphological characteristics. Detection of aneuploidy in human embryos. Thanks to the introduction of molecular-genetic screening of embryos, it is possible to identify aneuploid embryos via preimplantation g

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Drux, Rudolf. "Vom Leben aus der Retorte." Rhetorik 37, no. 1 (2018): 52–67. http://dx.doi.org/10.1515/rhet.2018.004.

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Abstract Since 1987, the year of birth of the first child conceived outside the womb, experiments with human life have been leading to an intense public debate about the benefits, chances and risks of research in reproductive medicine. For what had formerly existed in fictional worlds only, be it the alchemical mind game, the homunculus- recipe of Paracelsus or the breeding centre of Aldous Huxley’s Brave New World, was now happening in reality. With in vitro fertilization becoming a feasible alternative to creating offspring, the literary forms of representation for those technologies changed

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Goldstein, Lawrence. "Why Scientific Details are Important When Novel Technologies Encounter Law, Politics, and Ethics." Journal of Law, Medicine & Ethics 38, no. 2 (2010): 204–11. http://dx.doi.org/10.1111/j.1748-720x.2010.00480.x.

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Lost at times in the heat of debate about stem cell research, or any controversial advanced technology, is the need for precision in debate and discussion. The details matter a great deal, ranging from the need to use words that have precise definitions, to accurately quote colleagues and adversaries, and to cite scientific and medical results in a way that reflects the quality, rigor, and reliability of the work at issue. Regrettably, considerable inaccuracy has found its way into the debates about stem cells, on all sides, with consequent fogging of the issues.A key detail that is often over

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Tadepalli, Satya Kiranmai, and P. V. Lakshmi. "Application of Machine Learning and Artificial Intelligence Techniques for IVF Analysis and Prediction." International Journal of Big Data and Analytics in Healthcare 4, no. 2 (2019): 21–33. http://dx.doi.org/10.4018/ijbdah.2019070102.

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Infertility is the combination of factors that prevent pregnancy. It involves a lot of care and expertise while selecting the best embryo to lead to a successful pregnancy. Assistive reproductive technology (ART) helps to solve this issue. In vitro fertilization (IVF) is one of the methods of ART which is very popular. Artificial intelligence will have digital revolution and manifold advances in the field of reproductive medicine and will eventually provide immense benefits to infertile patients. The main aim of this article is to focus on the methods that can predict the accuracy of pregnancy

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Bongso, Ariff. "Oviductal cells and early conception." Reproductive Medicine Review 4, no. 1 (1995): 31–41. http://dx.doi.org/10.1017/s0962279900001046.

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The ability to bypass the oviduct by fertilizing human oocytes in vitro and then transferring the ensuing embryos into the uterine environment to produce pregnancies that can be carried to term (assisted reproductive technology, ART) has made the real functional significance of the fallopian tube come under debate. The question has been raised as to whether the oviduct is a simple conduit, providing for the transport of gametes and embryos, or whether it has any functional relevance to early conception. In the field of ART, some reports claim that transfer of embryos either to the uterus or to

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Lou, Hangying, Fang Le, Minhao Hu, et al. "Aberrant DNA Methylation of IGF2-H19 Locus in Human Fetus and in Spermatozoa From Assisted Reproductive Technologies." Reproductive Sciences 26, no. 7 (2018): 997–1004. http://dx.doi.org/10.1177/1933719118802052.

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Given the higher risk of developing imprinting disorders in assisted reproductive technology (ART)-conceived children, we hypothesized that ART may affect DNA methylation of the insulin-like growth factor 2 (IGF2), H19, small nuclear ribonucleoprotein polypeptide N (SNRPN) differentially methylated regions (DMRs) at the fetal stage, which in turn may be associated with sperm abnormalities. A total of 4 patient groups were recruited, namely, multifetal reduction following in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI; n = 56), multifetal reduction following controlled ova

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Ahemmed, Baiju, Vani Sundarapandian, Rohit Gutgutia, et al. "Outcomes and Recommendations of an Indian Expert Panel for Improved Practice in Controlled Ovarian Stimulation for Assisted Reproductive Technology." International Journal of Reproductive Medicine 2017 (2017): 1–14. http://dx.doi.org/10.1155/2017/9451235.

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Purpose.To improve success of in vitro fertilization (IVF), assisted reproductive technology (ART) experts addressed four questions. What is optimum oocytes number leading to highest live birth rate (LBR)? Are cohort size and embryo quality correlated? Does gonadotropin type affect oocyte yield? Should “freeze-all” policy be adopted in cycles with progesterone >1.5 ng/mL on day of human chorionic gonadotropin (hCG) administration?Methods.Electronic database search included ten studies on which panel gave opinions for improving current practice in controlled ovarian stimulation for ART.Resul

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Singh, Preksha T., Shreyans D. Singhvi, Utkarsh Kachhia, Trishala Punjabi, Shital Punjabi, and Rajesh Punjabi. "Retrospective study of multiple factors imparting effect on pregnancy outcomes in an in-vitro-fertilization centre." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 6 (2020): 2516. http://dx.doi.org/10.18203/2320-1770.ijrcog20202340.

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Background: Assisted reproductive technology (ART) cycles include in vitro fertilization of the sperm and ovum and transferring the embryo formed into the uterus of the patients. In ART cycles, there is still a shroud of doubt regarding the pregnancy outcomes of embryo transfer on day 3 versus the embryo transfers on day 5 as well the better pregnancy outcome with fresh versus frozen embryo transfer and the number of embryos transferred. This study is aimed to evaluate these factors and study the way to optimize methods to obtain highest pregnancy outcomes.Methods: A retrospective study was pe

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Singh, Pooja, Aradhana Kalra, Purnima K. Nadkarni, and Akshay K. Nadkarni. "Successful Live Births after Laparoscopic Management of Heterotypic Pregnancies in Assisted Reproductive Technology Cycles: A Tertiary Fertility Center Experience." International Journal of Infertility & Fetal Medicine 8, no. 3 (2017): 125–27. http://dx.doi.org/10.5005/jp-journals-10016-1161.

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ABSTRACT Background To review and analyze the incidence of heterotypic pregnancies after intracytoplasmic sperm injection (ICSI) and embryo transfer and to report pregnancy outcome after successful management of heterotypic pregnancies. Setting Nadkarni's 21st Century Hospitals and Test Tube Baby Center, Surat, Gujarat, India. Design Retrospective study. Materials and methods Retrospective data were taken from hospital records from January 2013 to December 2015. A total of 2,771 patients underwent in vitro fertilization IVF/ICSI, out of which 1,455 patients were pregnant (52.5%). Out of the pr

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Sabirova, V. L., and N. A. Ilizarova. "New approach in screening and treatment of chronic endometritis in patients with repeated failures of in vitro fertilization." Meditsinskiy sovet = Medical Council, no. 11 (August 8, 2020): 178–85. http://dx.doi.org/10.21518/2079-701x-2020-11-178-185.

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Introduction. The article presents the results of the study of preparation for assisted reproductive technology (ART) programs in patients with infertility combined with repeated failures of in vitro fertilization (IVF) programs against the background of chronic endometritis. New information about the pathogenesis of chronic endometritis in patients with failures of IVF programs was obtained in the study. The new integrated approach to treatment includes aspiration of endometrial cavity to remove pathological endometrium, intrauterine administration of highly purified hyaluronic acid sodium sa

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Avdotina, Jekaterina, Aleksandra Mezecka-Oleinika, Vija Silina, and Zane Vitina. "Pregnancy and live birth rates in women with endometriosis related infertility in Latvia." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 3 (2019): 808. http://dx.doi.org/10.18203/2320-1770.ijrcog20190495.

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Background: Women with endometriosis experience painful symptoms and/or infertility, others have no symptoms at all. According to European Society of Human Reproduction and Embryology guidelines, surgery and assisted reproductive technologies (ART) are an appropriate treatment in cases of endometriosis-associated infertility. There are controversial data on the results of surgery and ART in patients with endometriosis.Methods: Retrospective analysis including 99 infertile patients aged between 25 and 48 years old. All of them had laparoscopic surgery as the primary option. 51 of them undergoin

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Javed, Murid, Navid Esfandiari, Jason Swain, and Essam Michael. "Human Oocyte Cryopreservation - An Emerging ART Technique: Are We Heading in the Right Direction?" Journal of Reproductive and Stem Cell Biotechnology 2, no. 2 (2011): 109–20. http://dx.doi.org/10.1177/205891581100200205.

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Oocyte cryopreservation is a promising adjunct to human assisted reproductive technology. Slow rate freezing has been the cryopreservation standard for storage of sperm, embryos and, subsequently, oocytes. However, earlier concerns regarding damage to the meiotic spindle, loss of cortical granules and the low success rates as compared to the relative success of embryo cryopreservation caused little interest until the 1990s. Interest increased when many studies indicated that acceptable oocyte survival, in vitro fertilization, normal embryos and adequate blastocyst development can be achieved w

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Shurygina, Oksana V., Ol'ga Yu Vasilenko, Sergey N. Yukhimets, and Nikita A. Shipulin. "THE HISTORY, OPPORTUNITIES AND PROSPECTS OF TIME-LAPSE TECHNOLOGIES IN THE STUDY OF EARLY HUMAN EMBRYONIC DEVELOPMENT." Morphological newsletter 29, no. 1 (2021): 9–19. http://dx.doi.org/10.20340/mv-mn.2021.29(1).9-19.

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Despite advances in assisted reproductive technologies, the high failure rate of existing stimulation protocols remains a key industry challenge. One of the leading reasons for this is the limited ability to assess the biological potential of the embryo and its chances of implantation. Over the past ten years, the focus of attention in reproductive technologies has significantly shifted from the patient to the embryo, since the need to improve their effectiveness stimulates the need to understand the deep processes of early development of the embryo. In order to increase the effectiveness of i

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Sirard, Marc-André. "40 years of bovine IVF in the new genomic selection context." Reproduction 156, no. 1 (2018): R1—R7. http://dx.doi.org/10.1530/rep-18-0008.

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The development of a complex technology such as in vitro fertilization (IVF) requires years of experimentation, sometimes comparing several species to learn how to create the right in vitro environment for oocytes, spermatozoa and early embryos. At the same time, individual species characteristics such as gamete physiology and gamete interaction are recently evolved traits and must be analysed within the context of each species. In the last 40 years since the birth of Louise Brown, IVF techniques progressed and are now used in multiple domestic and non-domestic animal species around the world.

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Ferré, L. B., C. Fresno, M. E. Kjelland, and P. J. Ross. "29 Development and survival of bovine vitrified sexed IVF-derived embryos in vitro matured with pituitary or human recombinant follicle-stimulating hormone." Reproduction, Fertility and Development 31, no. 1 (2019): 140. http://dx.doi.org/10.1071/rdv31n1ab29.

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Improving in vitro production efficiency involves the development of effective oocyte in vitro maturation conditions. Although &gt;80% of cumulus-oocyte complexes (COC) undergo nuclear maturation, only approximately 30 to 35% of immature bovine COC develop to the blastocyst stage. Also, animal-sourced FSH is typically used in IVF, so an effective alternative using recombinant DNA technology is desirable. The aim of this study was to compare the effect of porcine (p) and recombinant human (rh)FSH concentrations on in vitro performance and post-thaw survival. Ovaries were collected from an a

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Жигалина, Д. И., Н. А. Скрябин, О. Р. Канбекова, А. Н. Марошкина, Е. О. Чуркин, and И. Н. Лебедев. "Structure of chromosomal abnormalities in the cycles of IVF-PGS." Nauchno-prakticheskii zhurnal «Medicinskaia genetika», no. 3() (March 29, 2019): 47–54. http://dx.doi.org/10.25557/2073-7998.2019.03.47-54.

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Актуальность: Ограниченный репродуктивный потенциал у человека и прогрессирующее ухудшение репродуктивного здоровья населения стали причиной развития вспомогательных репродуктивных технологий в последние десятилетия. С целью повышения вероятности имплантации бластоцисты, снижения частоты спонтанных абортов у семейных пар, которые имеют проблемы репродукции, в клиническую практику был введен преимплантационный генетический скрининг (ПГС). Культивирование эмбрионов человека in vitro в циклах экстракорпорального оплодотворении (ЭКО), а также возможность получения генетического материала при прове

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Li, Jingjie, Yue Gao, Lihuan Guan, et al. "Lipid Profiling of Peri-implantation Endometrium in Patients With Premature Progesterone Rise in the Late Follicular Phase." Journal of Clinical Endocrinology & Metabolism 104, no. 11 (2019): 5555–65. http://dx.doi.org/10.1210/jc.2019-00793.

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Abstract Context Late follicular phase elevation in serum progesterone (P) during controlled ovarian hyperstimulation negatively affects the outcome of assisted reproductive technology by contributing to endometrial-embryo asynchrony. There are still no data on lipid metabolite alterations during this process. Objectives To investigate alterations in the lipid profile during the window of implantation in patients with premature P rise. Design Lipidomic variations in the endometrium were evaluated by ultrahigh-performance liquid chromatography coupled with electrospray ionization high-resolutio

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Wakayama, S., S. Kishigami, V. T. Nguyen, et al. "380 FULL-TERM DEVELOPMENT OF MOUSE EMBRYOS PRODUCED FROM RECONSTRUCTED GIANT OOCYTES BY INTRACYTOPLASMIC SPERM HEAD INJECTION." Reproduction, Fertility and Development 19, no. 1 (2007): 305. http://dx.doi.org/10.1071/rdv19n1ab380.

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In mammals, unusually large diploid giant oocytes are ovulated occasionally, but as any fertilized embryos would be triploid, the potential of the cytoplasm to support normal development is unknown. However, if such giant oocytes possess normal cytoplasm, the oocytes or their excessive cytoplasm would have potential applications in the treatment of human infertility and would enhance the study of basic biology, such as the influence of cytoplasmic factors on genomic reprogramming. We reconstructed oocytes 2 to 9 times normal volume by electrofusion or mechanical fusion between intact and enucl

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Đorđević, Biljana. "Assisted reproductive technologies in centers for biomedical assisted fertilization within and outside the network plans in the Republic of Serbia and their financing." Timocki medicinski glasnik 46, no. 1 (2021): 5–10. http://dx.doi.org/10.5937/tmg2101005q.

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INTRODUCTION: Assisted reproduction technologies (ART) are technologies that are used today, in the treatment of infertility, on human germ cells (oocytes and sperm) and embryos. Currently in the Republic of Serbia, there are various procedures of assisted reproduction technologies that are used to treat infertility in patients depending on medical indications. The availability of assisted reproduction technologies has been evolving over the years, and their application differs in biomedically assisted fertilization centers that are in the Network Plan (state institutions) and outside the Netw

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Zmuidinaite, Raminta, Fady I. Sharara, and Ray K. Iles. "Current Advancements in Noninvasive Profiling of the Embryo Culture Media Secretome." International Journal of Molecular Sciences 22, no. 5 (2021): 2513. http://dx.doi.org/10.3390/ijms22052513.

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There have been over 8 million babies born through in vitro fertilization (IVF) and this number continues to grow. There is a global trend to perform elective single embryo transfers, avoiding risks associated with multiple pregnancies. It is therefore important to understand where current research of noninvasive testing for embryos stands, and what are the most promising techniques currently used. Furthermore, it is important to identify the potential to translate research and development into clinically applicable methods that ultimately improve live birth and reduce time to pregnancy. The c

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Sano, H., K. Matsuura, K. Naruse, and H. Funahashi. "215 APPLICATION OFA MICROFLUIDIC SPERM SORTER TO THE IN VITRO FERTILIZATION OF PORCINE OOCYTES." Reproduction, Fertility and Development 20, no. 1 (2008): 187. http://dx.doi.org/10.1071/rdv20n1ab215.

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In porcine IVF, polyspermy is a persistent obstacle to the efficient production of normal embryos in vitro. A microfluidic sperm sorter (MFSS; Strex Inc., Osaka, Japan) has been developed to isolate motile human spermatozoa (from diluted semen by 2 laminar flows in the microchannel). The motile spermatozoa can gradually accumulate in a chamber of the MFSS. In addition, we have succeeded in reducing the incidence of polyspermic penetration by a transient coincubation of oocytes with spermatozoa in the presence of caffeine, followed by culture of the oocytes in the absence of caffeine (2004 Repr

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Johnson, LA. "Sex preselection by flow cytometric separation of X and Y chromosome-bearing sperm based on DNA difference: a review." Reproduction, Fertility and Development 7, no. 4 (1995): 893. http://dx.doi.org/10.1071/rd9950893.

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Recent research on the flow cytometry of sperm for the purpose of predetermining gender of offspring has led to a validated method to separate X from Y chromosome-bearing sperm for use with in vitro fertilization and embryo transfer, intratubal insemination or intracytoplasmic sperm injection. The basis for the method is the sex chromosome-specific marker, DNA, which is present in greater amounts in X-bearing sperm than in Y-bearing sperm of mammals. Sperm are exposed to the vital dye Hoechst 33342 which binds to the minor groove of the DNA helix. Flow cytometric sorting of the sperm using a l

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Xu, Huiyu, Guoshuang Feng, Yuan Wei, et al. "Predicting Ectopic Pregnancy Using Human Chorionic Gonadotropin (hCG) Levels and Main Cause of Infertility in Women Undergoing Assisted Reproductive Treatment: Retrospective Observational Cohort Study." JMIR Medical Informatics 8, no. 4 (2020): e17366. http://dx.doi.org/10.2196/17366.

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Background Ectopic pregnancy (EP) is a serious complication of assisted reproductive technology (ART). However, there is no acknowledged mathematical model for predicting EP in the ART population. Objective The goal of the research was to establish a model to tailor treatment for women with a higher risk of EP. Methods From December 2015 to July 2016, we retrospectively included 1703 women whose serum human chorionic gonadotropin (hCG) levels were positive on day 21 (hCG21) after fresh embryo transfer. Multivariable multinomial logistic regression was used to predict EP, intrauterine pregnancy

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Gracias, Rochelle Heroina, Louis Fessy Thalakottoor, Parasuram Gopinath, and Gopinathan Kannoly Karunakaran. "Fertility Scoring Index: Cimar's Novel System to Predict assisted Reproductive Technology Success." International Journal of Infertility & Fetal Medicine 5, no. 2 (2014): 44–57. http://dx.doi.org/10.5005/jp-journals-10016-1081.

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ABSTRACT Background About 15% of all couples are infertile and require fertility treatment. With constantly improving clinical and laboratory procedures, pregnancy rates of about 30% per transfer are routinely reported. In non-donor-oocyte cycles, the percentage of in vitro fertilization/intracytoplasmic sperm injection (IVF/ ICSI) cycles that result in pregnancy ranges from 18 to 45%, depending on several factors (Society for Assisted Reproductive Technology 2009). But a patients concern is about the success rate—‘What is my chance of getting pregnant’? For the success in IVF/ICSI—embryo tran

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Ahmadi, Firoozeh, Farnaz Akhbari, SH Irani, M. Shiva, and A. Maghari. "A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Three-dimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran." Donald School Journal of Ultrasound in Obstetrics and Gynecology 10, no. 4 (2016): 398–402. http://dx.doi.org/10.5005/jp-journals-10009-1491.

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ABSTRACT Introduction To evaluate the role of endometrial thickness and volume using three-dimensional transvaginal ultrasound (3-D TVUS) in order to predict pregnancy outcome in assisted reproductive technology (ART) cycle on the day of human chorionic gonadotropin (hCG) administration. Materials and methods In this prospective study, the long protocol of controlled ovarian hyperstimulation was prescribed for women. Endometrial thickness and volume were measured using the 3-D TVUS, for 166 women undergoing ART cycle, on the day of hCG administration at Royan Institute, Tehran, Iran, between 2

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Das, Sankar Kumar, Priyanka Roy, and Krishna Kalita. "Elevated progesterone level and its consequences on IVF." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 2 (2019): 672. http://dx.doi.org/10.18203/2320-1770.ijrcog20190303.

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Background: Understanding of the embryo-endometrium dialogue is still far from being understood. During conventional in vitro fertilization cycles, progesterone elevation on the day of human chorionic gonadotropin administration refers to rising progesterone levels in the absence of either premature or a luteinizing hormone surge. Most research have reported that elevated progesterone had an adverse impact on the endometrial environment of fresh cycles, leading to a decrease in pregnancy rates.Methods: The current study was undertaken at Swagat hospital and research Centre, Bongaigaon, Assam (

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Chang, Peter, Susan Kenley, Tammy Burns, et al. "Recombinant human chorionic gonadotropin (rhCG) in assisted reproductive technology: results of a clinical trial comparing two doses of rhCG (OvidrelR) to urinary hCG (ProfasiR) for induction of final follicular maturation in in vitro fertilization–embryo transfer." Fertility and Sterility 76, no. 1 (2001): 67–74. http://dx.doi.org/10.1016/s0015-0282(01)01851-9.

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Timofeeva, Angelika, Yulia Drapkina, Ivan Fedorov, et al. "Small Noncoding RNA Signatures for Determining the Developmental Potential of an Embryo at the Morula Stage." International Journal of Molecular Sciences 21, no. 24 (2020): 9399. http://dx.doi.org/10.3390/ijms21249399.

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As part of the optimization of assisted reproductive technology programs, the aim of the study was to identify key small noncoding RNA (sncRNA) molecules that participate in maternal-to-zygotic transition and determine development potential and competence to form a healthy fetus. Small RNA deep sequencing followed by quantitative real-time RT-PCR was used to profile sncRNAs in 50 samples of spent culture medium from morula with different development potentials (no potential (degradation/developmental arrest), low potential (poor-quality blastocyst), and high potential (good/excellent quality b

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Kordowitzki, P., S. Klein, K. G. Hadeler, et al. "3 SIRT1—A POSSIBLE MARKER FOR REPRODUCTIVE AGING OF IN VIVO-DERIVED BOVINE OOCYTES?" Reproduction, Fertility and Development 29, no. 1 (2017): 109. http://dx.doi.org/10.1071/rdv29n1ab3.

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Maternal aging-associated reduction of oocyte viability is a common feature in mammals. Effective measures to counteract this process have not yet been developed. Cows are commonly used as a model of early human development, including maternal aging, because both species share a very high degree of similarity, including follicle selection, cleavage and blastocyst formation and a long reproductive lifespan. SIRT1, a member of the Sirtuin family, deacetylates transcriptional regulators localised in the nucleus and cytoplasm by a NAD+-dependent mechanism. Resveratrol (3,4′,5-trihydroxystilbene) i

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Kõks, S., A. Velthut, A. Sarapik, et al. "166 THE DIFFERENTIAL TRANSCRIPTOME AND ONTOLOGY PROFILES OF MURAL AND CUMULUS GRANULOSA CELLS IN STIMULATED HUMAN ANTRAL FOLLICLES." Reproduction, Fertility and Development 23, no. 1 (2011): 185. http://dx.doi.org/10.1071/rdv23n1ab166.

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Communication between various cell types in the ovary is a prerequisite for successful folliculogenesis and ovulation. In human antral follicles, granulosa cells divide into 2 distinct cell populations: mural (enveloping the antrum, MGC) and cumulus granulosa cells (surrounding the oocyte, CGC). During infertility treatment using in vitro fertilization (IVF), granulosa cells can be retrieved during puncture of stimulated follicles offering an excellent opportunity for analysing their functional properties. The aim of this study was to compare the transcriptomes of MGC and CGC. Twenty infertile

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Gonzalez, R., and E. Carnevale. "219 SORTING OF EQUINE SPERM USING A MICROFLUIDIC DEVICE AS A METHOD OF SPERM SELECTION FOR IN VITRO FERTILIZATION AND INTRACYTOPLASMIC SPERM INJECTION." Reproduction, Fertility and Development 28, no. 2 (2016): 241. http://dx.doi.org/10.1071/rdv28n2ab219.

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Microfluidic technology can be used for sperm separation. Microfluidic devices generate a fluid flow to sort sperm from a media reservoir into a collection chamber. In the human and mouse, the use of microfluidic devices resulted in the selection of sperm with improved sperm motility, normal morphology, and DNA integrity for in vitro fertilization (IVF), intrauterine insemination (IUI), and intracytoplasmic sperm injection (ICSI). With the use of microfluidic sperm separation, centrifugation can be eliminated, diminishing the risk of reactive oxygen species exposure and DNA damage. We hypothes

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Glavota, Sabrina. "Mitochondrial Replacement Therapy: Let the Science Decide." Michigan Technology Law Review, no. 27.2 (2021): 345. http://dx.doi.org/10.36645/mtlr.27.2.mitochondrial.

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Mitochondrial replacement therapy (MRT) is an in vitro fertilization technique designed to prevent women who are carriers of mitochondrial diseases from passing on these heritable genetic diseases to their children. It is an innovative assisted reproductive technology that is only legal in a small number of countries. The United States has essentially stagnated all opportunities for research and clinical trials on MRT through a rider in H.R.2029 – Consolidated Appropriations Act, 2016. The rider bans clinical trials on all therapies in which a human embryo is intentionally altered to include a

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Norrman, E., M. Petzold, T. D. Clausen, et al. "Type 1 diabetes in children born after assisted reproductive technology: a register-based national cohort study." Human Reproduction 35, no. 1 (2020): 221–31. http://dx.doi.org/10.1093/humrep/dez227.

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References STUDY QUESTION Do children born after assisted reproductive technology (ART) have an increased risk of developing type 1 diabetes? SUMMARY ANSWER Children born after ART were found to have an increased risk of type 1 diabetes in the unadjusted analysis, while after adjustment this association was only significant in children born after frozen embryo transfer. WHAT IS KNOWN ALREADY? Some studies raise concerns as to whether fertility treatments may influence long-term morbidity in children born after ART. Elevated blood pressure and altered glucose metabolism have been found after AR

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Priya, Dev, and Monika Saini. "Psychological impact of fertility treatment during the coronavirus pandemic and its legal aspect." Journal of Reproductive Healthcare and Medicine 2 (February 22, 2021): 119–25. http://dx.doi.org/10.25259/jrhm_6_2021.

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The emergence of severe acute respiratory syndrome coronavirus, a novel coronavirus in December 2019 was first identified in Wuhan, the capital city of China, Hubei Province that rapidly spread as worldwide pandemic, a global health emergency condition. The coronavirus disease 2019 (COVID-19) outbreak was declared as Public Health Emergency of International Concern on January 30, 2020, by the World Health Organization and later a world pandemic on March 11, 2020. In India, the first COVID-19 case was reported on January 30, 2020, and with increasing number of cases later nationwide lockdown wa

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Maziero, R. R. D., D. M. Paschoal, M. D. Guastali, et al. "162 EFFECT OF MEIOTIC ARREST USING BUTYROLACTONE I AND ROSCOVITINE IN RESISTANCE TO EMBRYO CRYOPRESERVATION." Reproduction, Fertility and Development 26, no. 1 (2014): 195. http://dx.doi.org/10.1071/rdv26n1ab162.

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In vitro embryo production by maturation, fertilization, and culture has become a valuable assisted reproductive technology in cattle breeding systems. However, even with the notable innovations in this system, the greatest obstacles for the complete success of this biotechnology are the low pregnancy rates after transfer and the greater sensitivity to cryopreservation. Thus, this study evaluated the effect of the addition of a meiotic arrest using butyrolactone I and roscovitine on in vitro production of bovine embryos. Nelore oocytes were matured in TCM-199 with Earle's salt + 10% FCS, FSH,

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