Gotowe bibliografie tematyczne / Hypoglycaemic potential

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Gotowa bibliografia na temat „Hypoglycaemic potential”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Hypoglycaemic potential"

Fabricius, Therese W., Clementine E. M. Verhulst, Peter L. Kristensen, et al. "Hyperinsulinaemic–hypoglycaemic glucose clamps in human research: a systematic review of the literature." Diabetologia 64, no. 4 (2021): 727–36. http://dx.doi.org/10.1007/s00125-020-05361-8.

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Abstract Aims/hypothesis The hyperinsulinaemic–hypoglycaemic glucose clamp technique has been developed and applied to assess effects of and responses to hypoglycaemia under standardised conditions. However, the degree to which the methodology of clamp studies is standardised is unclear. This systematic review examines how hyperinsulinaemic–hypoglycaemic clamps have been performed and elucidates potential important differences. Methods A literature search in PubMed and EMBASE was conducted. Articles in English published between 1980 and 2018, involving adults with or without diabetes, were inc

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Kern, Werner, Andreas Holstein, Christian Moenninghoff, Joachim Kienhöfer, Matthias Riedl, and Bernhard Kulzer. "Self-reported Hypoglycaemic Events in 2 430 Patients with Insulin-treated Diabetes in the German Sub-population of the HAT Study." Experimental and Clinical Endocrinology & Diabetes 125, no. 09 (2017): 592–97. http://dx.doi.org/10.1055/s-0043-112350.

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AbstractData concerning true hypoglycaemic incidence in insulin-treated patients with diabetes in real-world clinical practice are lacking in Germany. The aim of this analysis was to determine the incidence of hypoglycaemia experienced by the German cohort of patients enrolled in the global Hypoglycaemia Assessment Tool (HAT) study. This was a non-interventional, 6-month retrospective and 4-week prospective study using self-assessment questionnaires and patient diaries assessing patients aged ≥18 years in Germany, with type 1 diabetes (T1D) (n=811) or type 2 diabetes (T2D) (n=1 619) treated wi

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Jin, Fang-Xin, Yan Wang, Min-Ne Li, Ru-Jiang Li, and Jun-Tang Guo. "Intestinal glucagon-like peptide-1: A new player associated with impaired counterregulatory responses to hypoglycaemia in type 1 diabetic mice." World Journal of Diabetes 15, no. 8 (2024): 1764–77. http://dx.doi.org/10.4239/wjd.v15.i8.1764.

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BACKGROUND Impaired hypoglycaemic counterregulation has emerged as a critical concern for diabetic patients who may be hesitant to medically lower their blood glucose levels due to the fear of potential hypoglycaemic reactions. However, the patho-genesis of hypoglycaemic counterregulation is still unclear. Glucagon-like peptide-1 (GLP-1) and its analogues have been used as adjunctive therapies for type 1 diabetes mellitus (T1DM). The role of GLP-1 in counterregulatory dys-function during hypoglycaemia in patients with T1DM has not been reported. AIM To explore the impact of intestinal GLP-1 on

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Yskout, Marie, Joke Vliebergh, Hakan Bor, et al. "Hypoglycaemia after Initiation of CFTR Modulator Therapy in a Cystic Fibrosis Patient without Diabetes." Case Reports in Endocrinology 2023 (December 23, 2023): 1–4. http://dx.doi.org/10.1155/2023/9769119.

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Introduction. Cystic fibrosis transmembrane regulator (CFTR) modulator therapies improve respiratory function and glycaemic control in patients with cystic fibrosis (CF). The direct effect of CFTR modulator therapies on pancreatic function in patients without preexisting diabetes remains unclear. Case Presentation. An 18-year-old female with CF caused by F508del/F508del mutation, who had no diabetes, developed postprandial hypoglycaemias 6 months after initiation of elexacaftor, tezacaftor, and ivacaftor combination therapy (ETI). Symptoms were persisted after brief discontinuation of ETI, but

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Teale, J. D., W. F. Blum, and V. Marks. "Alleviation of Non-Islet Cell Tumour Hypoglycaemia by Growth Hormone Therapy is Associated with Changes in IGF Binding Protein-3." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 29, no. 3 (1992): 314–23. http://dx.doi.org/10.1177/000456329202900312.

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The hypoglycaemia caused by non-islet cell tumours is often associated with an increase in plasma insulin-like activity. In many cases there is a relative if not always absolute increase in plasma insulin-like growth factor II (IGF-II). Growth hormone (GH) secretion is almost invariably depressed as is the plasma insulin response to oral glucose. Despite the high concentration of IGFs (i.e. IGF-I and IGF-II) normally found in the plasma of healthy people their potential hypoglycaemic effect is not manifest due to the tightness with which they are bound to specific binding proteins (IGFBPs). Pl

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BJÖRKLUND, Anders O., Ulf K. C. ADAMSON, Per-Eric S. LINS, and L. Magnus R. WESTGREN. "Diminished insulin clearance during late pregnancy in patients with Type I diabetes mellitus." Clinical Science 95, no. 3 (1998): 317–23. http://dx.doi.org/10.1042/cs0950317.

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1.Intensive insulin treatment of patients with Type I diabetes mellitus during pregnancy is associated with a high frequency of serious hypoglycaemic events. A potential change in insulin metabolism during pregnancy may affect both the frequency and the severity of insulin-induced hypoglycaemia. 2.In 10 patients with Type I diabetes, during the third trimester of pregnancy and 5 to 13 months after delivery, hypoglycaemia was induced by the hyperinsulinaemic hypoglycaemic clamp technique. A constant high-dose intravenous insulin infusion was administered for 150 ;min and arterial blood glucose

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Etchie, Laju, Devaka Fernando, Vakkat Muraleedharan, and Ashok Poduval. "A Rare Cause of Severe Hypoglycaemia." Physician 6, no. 3 (2021): 1–5. http://dx.doi.org/10.38192/1.6.3.12.

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A 67-year old woman presented with an unwitnessed fall and decreased oral intake. She had a learning disability, hypertension, epilepsy, asthma, chronic iron deficiency anaemia, mild lymphopenia, osteoporosis and treated uterine cancer. After clinical review, she was treated for Hospital-acquired pneumonia (following a recent hospital admission) with possible aspiration. She was noted to have hyponatraemia secondary to dehydration. She was commenced on intravenous Levofloxacin and Metronidazole along with supportive care, based on antibiotic guidance due to her known allergy to penicillin.On d

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Setiani, Nur A., Rika L. Anggriani, and Anggi Restiasari. "Effect of Fermentation Time of Kombucha Tea on Its Hypoglycaemic Activity in Rats." Pharmacology and Clinical Pharmacy Research 4, no. 1 (2019): 5. http://dx.doi.org/10.15416/pcpr.v4i1.21384.

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia. Functional food, such as kombucha tea, is widely used as complementary treatment for type 2 diabetes mellitus. Kombucha tea is made through fermentation process of green or black tea using a microbial kombucha consortium (Acetobacter xylinum and several types of yeast). The aim of this study was to evaluate the effect of fermentation time of kombucha tea on its hypoglycaemic activity in rats. The green tea (Camellia sinensis) was fermented with kombucha consortium for 8, 14, and 21 days. Evaluation of hypoglycae

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Proskurina, I. A., E. A. Petraneva, and D. V. Goryachev. "Recommendations on the Clinical Trial Programme for Diabetes Medicines." Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 11, no. 2 (2021): 94–103. http://dx.doi.org/10.30895/1991-2919-2021-11-2-94-103.

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Diabetes is a serious public health problem and one of the major chronic noncommunicable diseases. A lengthy stepwise treatment, and the need for an individualised approach to antidiabetic therapy, pose serious challenges for medicine developers. For all new hypoglycaemic medicines, there has been a centralised authorisation procedure in the European Union (EU) since 2005, which ensures a unified approach to efficacy and safety assessment. The aim of the study was to analyse current requirements for planning clinical trials of hypoglycaemic medicines containing new active substances (except fo

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Zaccardi, Francesco, Suping Ling, Claire Lawson, Melanie J. Davies, and Kamlesh Khunti. "Severe hypoglycaemia and absolute risk of cause-specific mortality in individuals with type 2 diabetes: a UK primary care observational study." Diabetologia 63, no. 10 (2020): 2129–39. http://dx.doi.org/10.1007/s00125-020-05223-3.

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Abstract Aims/hypothesis Several pathophysiological mechanisms would suggest a causal link between hypoglycaemia and cardiovascular death; conversely, current knowledge would not support a causal relationship with other causes of death. To clarify the nature and the magnitude of the association between hypoglycaemia and death, we investigated the 5 year mortality risks for cardiovascular disease, cancer and other causes in individuals with type 2 diabetes admitted to hospital for a severe hypoglycaemic episode. Methods We defined in the UK Clinical Practice Research Datalink database a prevale

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Rozprawy doktorskie na temat "Hypoglycaemic potential"

Segolela, Jane Choene. "Potential effect of senna italica on glucose transport receptors - translocation go GLUT4 in NIH-3T3-L1 preadipocytes and C2C12 muscle cells." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1558.

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Thesis (M. Sc. (Biochemistry)) -- University of Limpopo, 2015 Diabetes mellitus is one of the major diseases worldwide that is life threatening and is reaching an epidemic proportion. The most important approach in reducing the burden of the disease worldwide is to search for effective, low cost hypoglycaemic drugs with fewer side effects. Past experimental evidence confirmed the hypoglycemic activity of many indigenous African medicinal plants. S. italica (Fabaceae family) is widely used by traditional healers to treat a number of diseases such as sexually transmitted diseases and other fo

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Little, Stuart Alexander. "Design, management and completion of the HypoCOMPaSS RCT evaluating potential for restoration of hypoglycaemia awareness in type 1 diabetes using conventional vs novel technologies : and exploration of potential phenotypes predicting persistent impaired awareness despite study intervention." Thesis, University of Newcastle upon Tyne, 2015. http://hdl.handle.net/10443/2841.

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Aim: To explore the extent to which impaired awareness of hypoglycaemia (IAH) can be improved using currently available treatment regimens in individuals with long-standing type 1 diabetes mellitus (T1DM), and to characterise those individuals whose awareness of hypoglycaemia did not improve. Methods: A multicentre, 2x2 factorial 24-week RCT (HypoCOMPaSS) comparing multiple daily injections (MDI) and continuous subcutaneous insulin infusion therapy (CSII) with or without real-time continuous glucose monitoring (RT) in a population with T1DM and IAH was designed. The study was undertaken in fiv

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Nurlatifah, Annisa Oktafianti, and 安妮莎. "Characterization of The Effect of Bitter Melon Extract on Intestinal Cells for the Exploration of Potential Hypoglycaemic Mechanism thereof." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/a4273n.

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碩士 國立屏東科技大學 生物科技系 106 ABSTRACT Student ID : M10518027 Title of Thesis : Characterization of The Effect of Bitter Melon Extract on Intestinal Cells for the Exploration of Potential Hypoglycaemic Mechanism thereof Total Pages : 66 Name of Institute : National Pingtung University of Science and Technology Name of Department : Biological Science and Technology Date of Graduation : July 2018 Degree Confered : Master Name of Student : Annisa Oktafianti Nurlatifah Advisor : Prof. Hsueh-Ling Cheng, PhD Prof. Dr.

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Książki na temat "Hypoglycaemic potential"

van Hooijdonk, Roosmarijn T. M., and Marcus J. Schultz. Insulin and oral anti-hyperglycaemic agents in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0050.

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Dysglycaemia is frequently seen in the intensive care unit (ICU). Hyperglycaemia, hypoglycaemia and glycaemic variability are all independently associated with mortality and morbidity in critically-ill patients. It is common practice to treat hypergycaemia in these patients, while at the same time preventing hypoglycaemia and glycaemic variability. Insulin infusion is preferred over oral anti–hyperglycaemic agents for glucose control in the ICU because of the highly unpredictable biological availability of oral anti-hyperglycaemic agents during critical illness. Many oral anti–hyperglycaemic a

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Mesotten, Dieter, and Sophie Van Cromphaut. Management of diabetic emergencies in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0260.

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The three major diabetic emergencies comprise diabetic ketoacidosis (DKA), hyperglycaemic hyperosmolar state (HHS), and prolonged hypoglycaemia. These complications are preventable, treatable, and rather infrequently lead to prolonged intensive care (ICU) admission. Hyperglycaemic crises, whether DKA in type 1 diabetics, or HHS in type 2 diabetics, are characterized by moderate to severe hypovolaemia, electrolyte disturbances and a potentially life-threatening trigger. Hence, airway–breathing–circulation securement, diagnosis, and treatment of the underlying condition, as well as fluid resusci

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Debaveye, Yves, Dieter Mesotten, and Greet Van den Berghe. Hyperglycaemia, diabetes, and other endocrine emergencies. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0069.

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Although endocrine pathology is usually treated in outpatient clinic, intensive care may be required when endocrinopathies are associated with other medical illnesses or reach a state of decompensation. Although endocrine emergencies are quite rare, they are potentially life-threatening, if not recognized promptly and managed effectively. Therefore, every clinician should always be attentive to a possible diagnosis of these complex disorders. The three major diabetic emergencies comprise diabetic ketoacidosis, hyperglycaemic hyperosmolar state, and prolonged hypoglycaemia. Hyperglycaemic crise

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Finfer, Simon. Glycaemic control in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0259.

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Hyperglycaemia is a near universal occurrence in critically-ill patients. In the last 10 years, control of blood glucose has been one of the most intensively studied areas of critical care medicine. It has become clear that control of blood glucose has the potential to affect both morbidity and mortality, and considerable uncertainty remains over many aspects of blood glucose management. Both hyperglycaemia and hypoglycaemia are associated with increased mortality and should be avoided wherever possible. Wide fluctuations in blood glucose concentration (referred to as increased glucose variabi

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Bleck, Thomas P. Pathophysiology and causes of seizures. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0231.

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Seizures result from imbalances between excitation and inhibition, and between neuronal synchrony and dyssynchrony. Current models implicate the cerebral cortex in the genesis of seizures, although thalamic mechanisms (particularly the thalamic reticular formation) are involved in the synchronization of cortical neurons. Often, the precipitants of a seizure in the critical care setting are pharmacological. Several mechanisms linked to critical illness can lead to seizures. Failure to remove glutamate and potassium from the extracellular space, functions performed predominantly by astrocytes, o

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Wilton, Niall, Brian J. Anderson, and Bruno Marciniak. Anatomy, physiology, and pharmacology in paediatric anaesthesia. Edited by Jonathan G. Hardman and Neil S. Morton. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0069.

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Anaesthesia for children is tempered by changes that occur during both growth and development. Drug dose is affected by size and clearance maturation processes as well as the changing body composition that occurs with age. All organ systems undergo these maturation changes and most are complete within the first few years of life. Normal physiological variables in infancy and childhood are quite different from adults. The central nervous, cardiovascular, and respiratory systems are particularly important. Cerebral immaturity and plasticity impacts sensitivity to drugs, pain responses, and behav

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Subhas, Kamalakkannan, and Martin Smith. Intensive care management after neurosurgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0369.

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The post-operative management of neurosurgical patients is directed towards the prevention, prompt detection, and management of surgical complications, and other factors that put the brain or spinal cord at risk. Close monitoring is required in the first 6–12 post-operative hours as deterioration in clinical status is usually the first sign of a potentially fatal complication. The majority of patients do not require complex monitoring or management beyond the first 12 hours after elective surgery, although prolonged intensive care unit management may be required for those who develop complicat

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Części książek na temat "Hypoglycaemic potential"

Rodriguez, Jhordany, Daniel Padilla, Lenert Bruce, Ben Thow, and Malcolm Pradhan. "Equitable Machine Learning for Hypoglycaemia Risk Management." In Studies in Health Technology and Informatics. IOS Press, 2024. http://dx.doi.org/10.3233/shti231089.

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We developed a machine learning (ML) model for the detection of patients with high risk of hypoglycaemic events during their hospital stay to improve the detection and management of hypoglycaemia. Our model was trained on data from a regional local health care district in Australia. The model was found to have good predictive performance in the general case (AUC 0.837). We conducted subgroup analysis to ensure that the model performed in a way that did not disadvantage population subgroups, in this case based on gender or indigenous status. We found that our specific problem domain assisted us

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Pandey, Nikhil, Priyanka Mishra, and Yamini B. Tripathi. "Antidiabetic Role of Swertia chirayita: Phytochemical and Pharmacological Perspective of a Himalayan Botanical." In Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123289123010007.

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As the Himalayan mountains and valleys keep on the continuous progression of their expansion during evolution, so does their cradle of medicinal plants. Humans started to find answers to various ailments by studying these medicinal plants. One such valuable medicinal plant from the Himalayas is called Swertia chirayita (Chiraito, SC), which shows a variety of therapeutic properties. SC has been shown to be effective in a wide therapeutic spectrum and acts as an anti-oxidant, anti-inflammatory, hypoglycaemic, anti-diabetic, anti-obesity, anti-tumor, anti-microbial, and chemoprotective agent. Du

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Paluru, Rajesh, and Devendra Singh Negi. "Brainstem Auditory Evoked Potentials in Type 2 Diabetes Mellitus." In Hearing Loss - From Multidisciplinary Teamwork to Public Health. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97469.

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Diabetes mellitus is a group of metabolic diseases characterized by hyperglycaemia resulting from defects in insulin secretion, insulin action or both. Diabetes affects many systems and produces complications in the human body, in those complications one is diabetic central neuropathy. The pathological mechanisms involved in the central neuropathy include chronic hyperglycaemia, hypoglycaemic episodes, angiopathy and blood–brain barrier dysfunction. Diabetic central neuropathy is detected by using of brainstem auditory evoked response (BAER), Visual evoked potential (VEP), somatosensory evoked

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Mande, Annie, Narender Malothu, and Tata Prasanna Kumari. "Evaluation of Neuroprotective Activity of Sida Cordifolia Against β-AMYLOID Protein Induced Loss of Cognitive Functions in Swiss Albino Mice." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00673.

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Neurodegenerative disorders are most prevalent in older patients. The plant, Sida Cordifolia is a perennial shrub which belongs to the family Malvaceae. S. Cordifolia was proved to possess analgesic, hypoglycaemic, hepatoprotective, and antioxidant activities. The main objective of the present work was to screen the neuroprotective potential of the whole plant S. Cordifolia. The preliminary phytochemical and the acute toxicity evaluation of the extract were done. The neuroprotective potential of the extract was evaluated with the help of Y- maze, water maze and step-down inhibitory avoidance t

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Moummou, Hanane, Jamal Karoumi, Mounir Tilaoui, et al. "Exploring the Therapeutic Potential from Moringa oleifera and Urtica dioica Bioactive Compounds in Managing Diabetes and Insulin Resistance." In The Global Burden of Disease and Risk Factors - Understanding and Management [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1004618.

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Diabetes is one of the ubiquitous metabolic disorders, indicating increasing chronic blood levels (chronic hyperglycaemia). Its three types are mostly caused by different pathogenic conditions (disorders in the secretion and/or regulation blood sugar insulin levels), often resulting from defects in insulin secretion and abnormal glucose tolerance. In addition, most people with diabetes have type 2 diabetes, which is characterised by insulin resistance and progressive beta-cell failure. Recently, there has been a growing demand for medicinal plants traditionally used to manage diabetes and its

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Choudhary, Pratik, and Stephanie A. Amiel. "Hypoglycaemia in the treatment of diabetes mellitus." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1435.

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Hypoglycaemia (low blood glucose concentration) is the most important acute complication of the pharmacological treatment of diabetes mellitus. Low blood glucose impairs brain (and, potentially, cardiac) function. The brain has minimal endogenous stores of energy, with small amounts of glycogen in astroglial cells. The brain is therefore largely dependent on circulating glucose as the substrate to fuel cerebral metabolism and support cognitive performance. If blood glucose levels fall sufficiently, cognitive dysfunction is inevitable. In health, efficient glucose sensing and counterregulatory

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Rasheed Fetian, Issa. "Unveiling the Significance of the ‘Bathtub’ Shape in Blood Glucose Curve Analysis." In Hypoglycemia - New Insights [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1003746.

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Despite extensive research on insulin usage in diabetes, an effective method for regulating insulin dosage and timing has not emerged. Self-monitoring of blood glucose (SMBG) is crucial for diabetes self-care, but its utility is limited in intense insulin treatments. Moreover, persistent nighttime hypoglycaemia anxiety and neuropathic gastric issues pose significant challenges for patients with elevated nocturnal blood sugar and frequent post-meal hypoglycaemia. The “bathtub” curve outlines a daily glucose profile where levels spike after dinner, normalizing only after morning correction. This

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Waclawski, Eugene R., and Geoff Gill. "Diabetes mellitus and other endocrine disorders." In Fitness for Work. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199643240.003.0015.

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A few studies of employment and diabetes in the UK indicate some increase in sickness absence. Recent research on the impact of hypoglycaemia at work indicated that severe hypoglycaemia was uncommon. Serious morbidity including accidents or injuries associated with hypoglycaemia at work was very uncommon. Information is still needed on the impact of particular work activities on diabetic control, especially shift work and vocational driving. Because of the paucity of definitive information, the advice given to diabetic workers is often arbitrary and employment decisions are taken with little s

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Gunst, Jan, Yves Debaveye, and Greet Van den Berghe. "Stress hyperglycaemia and endocrine emergencies." In The ESC Textbook of Intensive and Acute Cardiovascular Care, edited by Marco Tubaro, Pascal Vranckx, Eric Bonnefoy-Cudraz, Susanna Price, and Christiaan Vrints. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198849346.003.0068.

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Although endocrine pathology is usually treated in an outpatient clinic, intensive care may be required when endocrinopathies are associated with other medical illnesses or reach a state of decompensation. Although endocrine emergencies are quite rare, they are potentially life-threatening if not recognised promptly and managed effectively. Therefore, every clinician should always be attentive to a possible diagnosis of these complex disorders. The three major diabetic emergencies comprise diabetic ketoacidosis, hyperglycaemic hyperosmolar state, and prolonged hypoglycaemia. Hyperglycaemic cri

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Illingworth, Karen A., Karen H. Simpson, and Sue Swales. "Sedation." In Anaesthesia and Analgesia in Emergency Medicine, Second Edition. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780192629098.003.0010.

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Abstract The combination of sedation and analgesic drugs is potentially hazardous and should only be used by doctors trained in the management of unconscious patients. Monitoring and resuscitation equipment must be available when sedation is given. Patients who have received sedation should recover in a properly staffed and equipped area. It is unusual for severe agitation to respond to sedation alone. Before using drugs to calm such a patient a diagnosis should be made. Consider hypoxaemia, hypoglycaemia, urinary retention, or cerebral problems such as a head injury.

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