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Artykuły w czasopismach na temat „Hypoglycemia – Epidemiology”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 1 lutego 2022

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1

Kim, Hae Jin. "Epidemiology of Hypoglycemia in Diabetes." Korean Clinical Diabetes 9, no. 2 (2008): 91. http://dx.doi.org/10.4093/kcd.2008.9.2.91.

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2

Klimontov, Vadim V. "Impaired hypoglycemia awareness in diabetes: epidemiology, mechanisms and therapeutic approaches." Diabetes mellitus 21, no. 6 (February 18, 2019): 513–23. http://dx.doi.org/10.14341/dm9597.

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Impaired awareness of hypoglycemia (IAH) is a frequent complication of insulin therapy. Up to half insulin-treated individuals with type 1 and type 2 diabetes report the problems with hypoglycemia awareness, and 1525% of patients have a permanent IAH. A recurrent hypoglycemia is a cornerstone in IAH formation. The repeated episodes of hypoglycemia impair neurohumoral response to hypoglycemia, reduce its symptoms and induce inadequate brain adaptation to low glucose levels. In this regard, the IAH phenomenon can be considered as an example of "metabolic memory" in diabetes. The IAH

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3

Ahmad, Iram, Leila R. Zelnick, Zona Batacchi, Nicole Robinson, Ashveena Dighe, Jo-Anne E. Manski-Nankervis, John Furler, et al. "Hypoglycemia in People with Type 2 Diabetes and CKD." Clinical Journal of the American Society of Nephrology 14, no. 6 (April 17, 2019): 844–53. http://dx.doi.org/10.2215/cjn.11650918.

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Background and objectivesAmong people with diabetes mellitus, CKD may promote hypoglycemia through altered clearance of glucose-lowering medications, decreased kidney gluconeogenesis, and blunted counter-regulatory response. We conducted a prospective observational study of hypoglycemia among 105 individuals with type 2 diabetes treated with insulin or a sulfonylurea using continuous glucose monitors.Design, setting, participants & measurementsWe enrolled 81 participants with CKD, defined as eGFR<60 ml/min per 1.73 m2, and 24 control participants with eGFR≥60 ml/min per 1.73 m2 frequenc

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4

Van Staa, Tjeerd, Lucien Abenhaim, and Johanne Monette. "Rates of hypoglycemia in users of sulfonylureas." Journal of Clinical Epidemiology 50, no. 6 (June 1997): 735–41. http://dx.doi.org/10.1016/s0895-4356(97)00024-3.

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5

Kumar, JuvvaGowtham, KPP Abhilash, RamaPrakasha Saya, Neeha Tadipaneni, and JMaheedhar Bose. "A retrospective study on epidemiology of hypoglycemia in Emergency Department." Indian Journal of Endocrinology and Metabolism 21, no. 1 (2017): 119. http://dx.doi.org/10.4103/2230-8210.195993.

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6

Awoniyi, Omodele, Rabia Rehman, and Samuel Dagogo-Jack. "Hypoglycemia in Patients with Type 1 Diabetes: Epidemiology, Pathogenesis, and Prevention." Current Diabetes Reports 13, no. 5 (August 4, 2013): 669–78. http://dx.doi.org/10.1007/s11892-013-0411-y.

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7

Ginde, A. A., R. M. Lieberman, D. J. Pallin, and C. A. Camargo. "169: Emergency Department Visits for Hypoglycemia: Epidemiology, Patient Education and Outcomes." Annals of Emergency Medicine 50, no. 3 (September 2007): S54. http://dx.doi.org/10.1016/j.annemergmed.2007.06.202.

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8

Min, Jea Young, Caroline A. Presley, Jennifer Wharton, Marie R. Griffin, Robert A. Greevy, Adriana M. Hung, Jonathan Chipman, Carlos G. Grijalva, Amber J. Hackstadt, and Christianne L. Roumie. "Accuracy of a composite event definition for hypoglycemia." Pharmacoepidemiology and Drug Safety 28, no. 5 (March 6, 2019): 625–31. http://dx.doi.org/10.1002/pds.4712.

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9

Ratzki-Leewing, Alexandria, Stewart B. Harris, Selam Mequanint, Sonja M. Reichert, Judith Belle Brown, Jason Edward Black, and Bridget L. Ryan. "Real-world crude incidence of hypoglycemia in adults with diabetes: Results of the InHypo-DM Study, Canada." BMJ Open Diabetes Research & Care 6, no. 1 (April 2018): e000503. http://dx.doi.org/10.1136/bmjdrc-2017-000503.

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ObjectiveVery few real-world studies have been conducted to assess the incidence of diabetes-related hypoglycemia. Moreover, there is a paucity of studies that have investigated hypoglycemia among people taking secretagogues as a monotherapy or in combination with insulin. Accordingly, our research team developed and validated the InHypo-DM Person with Diabetes Mellitus Questionnaire (InHypo-DMPQ) with the aim of capturing the real-world incidence of self-reported, symptomatic hypoglycemia. The questionnaire was administered online to a national sample of Canadians (≥18 years old) with type 1

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10

Brož, Jan, and Jana Urbanová. "A general view of epidemiology of hypoglycemia in type 1 and type 2 diabetes mellitus." Vnitřní lékařství 65, no. 4 (April 1, 2019): 289–94. http://dx.doi.org/10.36290/vnl.2019.050.

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11

Nam, Young Hee, Colleen M. Brensinger, Warren B. Bilker, Charles E. Leonard, and Sean Hennessy. "Investigation of Concomitant Use of Alzheimer’s Disease Drugs with Sulfonylureas and Serious Hypoglycemia." Epidemiology 32, no. 1 (September 21, 2020): e3-e5. http://dx.doi.org/10.1097/ede.0000000000001263.

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12

Wickström, Ronny, Beatrice Skiöld, Gunnar Petersson, Olof Stephansson, and Maria Altman. "Moderate neonatal hypoglycemia and adverse neurological development at 2–6 years of age." European Journal of Epidemiology 33, no. 10 (July 20, 2018): 1011–20. http://dx.doi.org/10.1007/s10654-018-0425-5.

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13

Mathur, Arvind, Mohit Kackar, Indu Thanvi, and Harish Agarwal. "STUDY OF CLINICAL FEATURES AND EPIDEMIOLOGY OF COMPLICATED VIVAX MALARIA." International Journal of Research -GRANTHAALAYAH 7, no. 9 (September 30, 2019): 47–51. http://dx.doi.org/10.29121/granthaalayah.v7.i9.2019.556.

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Severe and complicated malaria is defined by the World Health Organization Malaria Action Programme in June 19851 as the presence of one or more of the following conditions in a slide confirmed diagnosed case of malaria cerebral malaria, severe anemia, renal failure, pulmonary edema or adult respiratory distress syndrome, hypoglycemia, circulatory collapse or shock, spontaneous bleeding, repeated generalized convulsions, acidemia or acidosis, macroscopic hemoglobinuria, impairment of consciousness less marked than unarousable coma,, hyperparasitemia, jaundice, hyperpyrexia, and the presence of

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14

Gorrell, Jennifer Justice, Jennifer Schoelles Williams, and Paula Powell. "Review and Update of Insulin Dependent Diabetes Mellitus." Journal of Pediatric Pharmacology and Therapeutics 8, no. 4 (October 1, 2003): 252–65. http://dx.doi.org/10.5863/1551-6776-8.4.252.

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The purpose of this article is to provide the health care practitioner with a comprehensive review of the pathophysiology and treatment of Type 1 Diabetes Mellitus. Traditionally, insulin has been administered via an insulin syringe. In the recent past, diabetes research has focused on developing more convenient insulin delivery devices and longer acting insulin's in hopes of increasing compliance with insulin therapy and improving the management of Type 1 diabetes in both children and adults. Rapidly developing approaches to insulin delivery for Type 1 diabetes continue to be developed at a r

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15

Moen, Maureen F., Min Zhan, Van Doren Hsu, Lori D. Walker, Lisa M. Einhorn, Stephen L. Seliger, and Jeffrey C. Fink. "Frequency of Hypoglycemia and Its Significance in Chronic Kidney Disease." Clinical Journal of the American Society of Nephrology 4, no. 6 (May 7, 2009): 1121–27. http://dx.doi.org/10.2215/cjn.00800209.

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16

Han, Kyungdo, Jae-Seung Yun, Yong-Moon Park, Yu-Bae Ahn, Jae-Hyoung Cho, Seon-Ah Cha, and Seung-Hyun Ko. "Development and validation of a risk prediction model for severe hypoglycemia in adult patients with type 2 diabetes: a nationwide population-based cohort study." Clinical Epidemiology Volume 10 (October 2018): 1545–59. http://dx.doi.org/10.2147/clep.s169835.

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17

Chu, Yeh-Wen, Hsuan-Ming Lin, Jhi-Joung Wang, Shih-Feng Weng, Chih-Ching Lin, and Chih-Chiang Chien. "Epidemiology and outcomes of hypoglycemia in patients with advanced diabetic kidney disease on dialysis: A national cohort study." PLOS ONE 12, no. 3 (March 29, 2017): e0174601. http://dx.doi.org/10.1371/journal.pone.0174601.

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18

Tovar-Acero, Catalina, María Camila Velasco, Paula Andrea Avilés-Vergara, Dina Marcela Ricardo-Caldera, Erasmo Manuel Alvis, Javier Ramirez - Montoya, and Maria Fernanda Yasnot Acosta. "Liver and kidney dysfunction, hypoglycemia, and thrombocytopenia in Plasmodium vivax malaria patients at a Colombian Northwest region." Parasite Epidemiology and Control 13 (May 2021): e00203. http://dx.doi.org/10.1016/j.parepi.2021.e00203.

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19

Núñez, Mercedes, Silvia Díaz, Tatiana Dilla, Jesús Reviriego, and Antonio Pérez. "Epidemiology, Quality of Life, and Costs Associated with Hypoglycemia in Patients with Diabetes in Spain: A Systematic Literature Review." Diabetes Therapy 10, no. 2 (January 19, 2019): 375–92. http://dx.doi.org/10.1007/s13300-019-0563-0.

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20

Yaffe, Kristine, Cherie Falvey, Nathan Hamilton, Ann Schwartz, Tamara Harris, Andrea Metti, Ronald Shorr, Elsa Strotmeyer, and Eleanor Simonsick. "O2-10-03: Hypoglycemia and dementia: A reciprocal relationship?" Alzheimer's & Dementia 8, no. 4S_Part_7 (July 2012): P254—P255. http://dx.doi.org/10.1016/j.jalz.2012.05.680.

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21

Sokolov, Yury Y., Mariya A. Melikyan, Sergey A. Karpachev, Vladimir R. Druzhinin, Ekaterina A. Tashirova, Dmitry N. Brovin, and Oleg S. Danilenko. "Laparoscopic distal pancreatectomy in 16 years girl with insulinoma." Endocrine Surgery 10, no. 3 (March 9, 2017): 26–32. http://dx.doi.org/10.14341/serg2016326-32.

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We present a clinical case of insulinoma in 16 years-old girl. The patient complained about episodes of loss of consciousness, followed by retrograde amnesia and accompanied by weakness and dizziness. The patient was transferred to the Department of Endocrinology, where hypoglycemia was detected (2.0-2.5 mmol/l). Topical diagnosis of insulinoma was evidentiated with the help of radiological methods - multislice CT and contrast-enhanced MRI, which revealed an oval tumor 12x10 mm. The molecular genetic analysis of MEN1 gene was performed – no mutations were revealed. Prescribed Proglikem (diazox

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22

PAMBIANCO, GEORGIA, and TREVOR J. ORCHARD. "Severe Hypoglycemia (SH) and Diabetic Ketoacidosis (DKA) Hospitalization Rates—Twenty-Five Years in the Epidemiology of Diabetes Complications (EDC) Study." Diabetes 67, Supplement 1 (May 2018): 1263—P. http://dx.doi.org/10.2337/db18-1263-p.

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23

Van Staa, Tjeerd-Pieter, and Lucien Abenhaim. "The quality of information recorded on a UK database of primary care records: A study of hospitalizations due to hypoglycemia and other conditions." Pharmacoepidemiology & Drug Safety 3, no. 1 (January 1994): 15–21. http://dx.doi.org/10.1002/pds.2630030106.

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24

Iloh, GabrielUche Pascal, and AgwuNkwa Amadi. "Epidemiology of hypoglycemia among ambulatory Type 2 diabetic patients in a primary care clinic of a tertiary hospital in Southeastern Nigeria." Journal of Health Research and Reviews 5, no. 2 (2018): 57. http://dx.doi.org/10.4103/jhrr.jhrr_37_17.

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25

Klimontov, Vadim V., Mikhail M. Lazarev, Andrey Ju Letyagin, Dinara M. Bulumbaeva, and Natalia P. Bgatova. "Lipodystrophy at the insulin injection sites: current trends in epidemiology, diagnostics and prevention." Diabetes mellitus 23, no. 2 (June 26, 2020): 161–73. http://dx.doi.org/10.14341/dm12095.

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Lipodystrophy at the injection sites is most common local complication of insulin therapy. The history of its study started in 1926, when first cases of lipoatrophy at the sites of insulin injections were described. As we moved to human insulin and insulin analogues, immune mediated atrophic form of lipodystrophy has been replaced by hypertrophic one, which reflects anabolic and mitogenic effect of insulin. Lipohypertrophy at the injection sites is detected by physical examination in 40-70% of insulin-treated subjects. The detection efficiency depends on health care provider`s skills. Th

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26

Fährmann, Elke R., Laura Adkins, Cameron J. Loader, Hyoil Han, Kevin M. Rice, James Denvir, and Henry K. Driscoll. "Severe hypoglycemia and coronary artery calcification during the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study." Diabetes Research and Clinical Practice 107, no. 2 (February 2015): 280–89. http://dx.doi.org/10.1016/j.diabres.2014.10.007.

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Zherdоva, N., and B. Mankovsky. "Characteristics of cognitive function in patients with diabetes mellitus type 1 younger depending transferred hypoglycemic conditions." East European Journal of Neurology, no. 1(13) (March 20, 2017): 17–21. http://dx.doi.org/10.33444/2411-5797.2017.1(13).17-21.

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Many studies focus on the effect of compensation of diabetes, glucose-lowering therapy of choice, the influence of cardio - vascular diseases in the state of cognition. At the same time, not enough attention is paid to cognitive impairment in patients with type 1 diabetes mellitus, especially young people. The aim of our study was to investigate the prognostic factors of dementia in patients with type 1 diabetes mellitus are younger. 33 patients were examined with type 1 diabetes and 10 people in the control group. Of the 33 patients with diabetes, 21 people had hypoglycemia in the last 3 mont

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28

Yarrington, Michael E., Deverick J. Anderson, Elizabeth Dodds Ashley, Travis Jones, Angelina Davis, Melissa Johnson, Yuliya Lokhnygina, Daniel J. Sexton, and Rebekah W. Moehring. "Impact of FDA black box warning on fluoroquinolone and alternative antibiotic use in southeastern US hospitals." Infection Control & Hospital Epidemiology 40, no. 11 (September 2, 2019): 1297–300. http://dx.doi.org/10.1017/ice.2019.247.

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AbstractWe analyzed antibiotic use data from 29 southeastern US hospitals over a 5-year period to determine changes in antibiotic use after the fluoroquinolone US Food and Drug Administration (FDA) advisory update in 2016. Fluoroquinolone use declined both before and after the FDA announcement, and the use of select, alternative antibiotics increased after the announcement.Fluoroquinolones are among the 4 most commonly prescribed antibiotic classes.1,2 Postmarketing reports of serious adverse events linked to fluoroquinolones include tendonitis, neuropathy, hypoglycemia, psychiatric side effec

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Scheld, Michael W., Brian Wispelwey, and Richard D. Pearson. "Pentamidine: A Review." Infection Control & Hospital Epidemiology 12, no. 6 (June 1991): 375–82. http://dx.doi.org/10.1086/646360.

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With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has increased greatly. This review summarizes the pharmacology, clinical experience in the treatment of Pneumocystis carinii pneumonia, and toxicity of pentamidine. Data are conflicting as to whether pentamidine is more or less effective than trimethoprim-sulfamethoxazole (TMP-SX) for the treatment of P carinii pneumonia in individuals with AIDS, but due to its toxicity and expense, it is considered as second-line therapy for P carinii pneumonia by many authorities. Hypoglyce

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Ross, Jennifer A., John W. Downs, Lindsay A. Bazydlo, Paige H. Bordwine, Catherine E. Gineste, Marissa C. Kopatic, Saumitra V. Rege, et al. "Outbreak of Severe Hypoglycemia After Ingestion of a Male Enhancement Supplement — Virginia, August–November 2019." MMWR. Morbidity and Mortality Weekly Report 69, no. 24 (June 19, 2020): 740–43. http://dx.doi.org/10.15585/mmwr.mm6924a3.

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Cozza, Justin, Tuong Vi Cassandra Do, Shyam Ganti, and Jayaramakrishna Depa. "The Ugly Side of Colchicine." Journal of Investigative Medicine High Impact Case Reports 9 (January 2021): 232470962110297. http://dx.doi.org/10.1177/23247096211029744.

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We report a rare case of a 32-year-old male who ingested 32.4 to 54 mg of colchicine and presented after 44 hours. He developed progressive multiple organ failure with shock, acute kidney failure, troponemia, pancytopenia, absolute neutropenia, disseminated intravascular coagulation, acute liver failure, rhabdomyolysis, and lactic acidosis. He also developed electrolyte abnormalities and refractory hypoglycemia. Initial treatment consisted of activated charcoal, fluids, and broad-spectrum antibiotics with supportive treatment of mechanical ventilation, hemodialysis, vasopressors, N-acetylcyste

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32

Finn, Erin, Kimberly Kripps, Christina Chambers, Michele Rapp, Naomi J. L. Meeks, Fang Xu, Wuyan Chen, Austin A. Larson, and Natalie J. Nokoff. "A Novel Intronic Pathogenic Variant in STAR With a Dominant Negative Mechanism Causes Attenuated Lipoid Congenital Adrenal Hyperplasia." Journal of Investigative Medicine High Impact Case Reports 9 (January 2021): 232470962110146. http://dx.doi.org/10.1177/23247096211014685.

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Lipoid congenital adrenal hyperplasia (LCAH) is typically inherited as an autosomal recessive condition. There are 3 reports of individuals with a dominantly acting heterozygous variant leading to a clinically significant phenotype. We report a 46,XY child with a novel heterozygous intronic variant in STAR resulting in LCAH with an attenuated genital phenotype. The patient presented with neonatal hypoglycemia and had descended testes with a fused scrotum and small phallus. Evaluation revealed primary adrenal insufficiency with deficiencies of cortisol, aldosterone, and androgens. He was found

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Muanda, Flory T., Matthew A. Weir, Lavanya Bathini, Kristin K. Clemens, Vlado Perkovic, Manish M. Sood, Eric McArthur, Jessica M. Sontrop, Richard B. Kim, and Amit X. Garg. "Higher-Dose Sitagliptin and the Risk of Congestive Heart Failure in Older Adults with CKD." Clinical Journal of the American Society of Nephrology 15, no. 12 (November 25, 2020): 1728–39. http://dx.doi.org/10.2215/cjn.08310520.

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Background and objectivesSitagliptin, a dipeptidyl peptidase-4 inhibitor, is commonly prescribed to patients with type 2 diabetes. As this drug is primarily eliminated by the kidney, a reduced dose is recommended for patients with CKD. Some evidence suggests that sitagliptin is associated with a higher risk of congestive heart failure, particularly at higher doses. We compare the 1-year risk of death or hospitalization with congestive heart failure in patients with CKD newly prescribed sitagliptin at >50 versus ≤50 mg/d.Design, setting, participants, & measurementsThis population-based

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Punnath, Kishore, Kiran K. Dayanand, Valleesha N. Chandrashekar, Rajeshwara N. Achur, Srinivas B. Kakkilaya, Susanta K. Ghosh, Suchetha N. Kumari, and D. Channe Gowda. "Association between Inflammatory Cytokine Levels and Thrombocytopenia during Plasmodium falciparum and P. vivax Infections in South-Western Coastal Region of India." Malaria Research and Treatment 2019 (April 11, 2019): 1–10. http://dx.doi.org/10.1155/2019/4296523.

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Background. Thrombocytopenia is a most commonly observed complication during malaria infections. Inflammatory cytokines such as IL-1, IL-6, and IL-10 have been documented in malaria induced thrombocytopaenia. This study was aimed to understand the possible relationship between inflammatory cytokines across varying degrees of thrombocytopenia during P. vivax, P. falciparum, and mixed infections. Methods. A hospital-based cross sectional study was conducted at District Wenlock Hospital in Mangaluru, a city situated along the south-western coastal region of Arabian Sea in India. In this study, bl

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35

Kuo, Yu-Min, and Chu-Wan Lee. "P1-336: Hypoglycemia induces tau hyperphosphorylation and learning and memory deficit in Wistar rats." Alzheimer's & Dementia 6 (July 2010): S271. http://dx.doi.org/10.1016/j.jalz.2010.05.889.

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Burne, Rebecca M., and Michal Abrahamowicz. "Adjustment for time-dependent unmeasured confounders in marginal structural Cox models using validation sample data." Statistical Methods in Medical Research 28, no. 2 (August 24, 2017): 357–71. http://dx.doi.org/10.1177/0962280217726800.

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Large databases used in observational studies of drug safety often lack information on important confounders. The resulting unmeasured confounding bias may be avoided by using additional confounder information, frequently available in smaller clinical “validation samples”. Yet, no existing method that uses such validation samples is able to deal with unmeasured time-varying variables acting as both confounders and possible mediators of the treatment effect. We propose and compare alternative methods which control for confounders measured only in a validation sample within marginal structural C

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McNay, Ewan, Pattie S. Green, and Suzanne Craft. "P1-132: Type 2 diabetes and recurrent hypoglycemia both elevate hippocampal amyloid, but by different mechanisms." Alzheimer's & Dementia 6 (July 2010): S212. http://dx.doi.org/10.1016/j.jalz.2010.05.681.

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Kennedy, Kaitlin E., Chengwen Teng, Taylor M. Patek, and Christopher R. Frei. "2296. Hypoglycemia Risk with Antibiotics: An Epidemiologic Surveillance Study of the FDA Adverse Event Reporting System (FAERS)." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S787. http://dx.doi.org/10.1093/ofid/ofz360.1974.

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Abstract Background In July of 2018, the FDA published a drug safety warning for the potential risk of developing hypoglycemia with fluoroquinolones. Some studies have evaluated the potential risk of developing hypoglycemia with linezolid and tigecycline. A few case reports have also been published that report hypoglycemia from cefditoren, doxycycline, and trimethoprim-sulfamethoxazole use. Since data comparing various antibiotics and the risk of developing hypoglycemia is limited, the objective of this study was to evaluate the association between hypoglycemia and antibiotics using the FDA Ad

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Pöhlmann, Johannes, Beth D. Mitchell, Sanjay Bajpai, Beatrice Osumili, and William J. Valentine. "Nasal Glucagon Versus Injectable Glucagon for Severe Hypoglycemia: A Cost-Offset and Budget Impact Analysis." Journal of Diabetes Science and Technology 13, no. 5 (January 30, 2019): 910–18. http://dx.doi.org/10.1177/1932296819826577.

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Background: Severe hypoglycemic events (SHEs) in patients with diabetes are associated with substantial health care costs in the United States (US). Injectable glucagon (IG) is currently available for treatment of severe hypoglycemia but is associated with frequent handling errors. Nasal glucagon (NG) is a novel, easier-to-use treatment that is more often administered successfully. The economic impact of this usability advantage was explored in cost-offset and budget impact analyses for the US setting. Methods: A health economic model was developed to estimate mean costs per SHE for which trea

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40

Lacy, Mary E., Paola Gilsanz, Michal Schnaider Beeri, Andrew J. Karter, Charles P. Quesenberry, and Rachel A. Whitmer. "P3-496: SEVERE HYPOGLYCEMIA AND COGNITIVE FUNCTIONING IN OLDER ADULTS WITH TYPE 1 DIABETES: THE STUDY OF LONGEVITY IN DIABETES (SOLID)." Alzheimer's & Dementia 14, no. 7S_Part_24 (July 1, 2006): P1312. http://dx.doi.org/10.1016/j.jalz.2018.06.1860.

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Wang, Jianjun, and Fiammetta Cosci. "Neonatal Withdrawal Syndrome following Late in utero Exposure to Selective Serotonin Reuptake Inhibitors: A Systematic Review and Meta-Analysis of Observational Studies." Psychotherapy and Psychosomatics 90, no. 5 (2021): 299–307. http://dx.doi.org/10.1159/000516031.

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<b><i>Introduction:</i></b> A clear picture of neonatal withdrawal signs due to in utero selective serotonin reuptake inhibitor (SSRI) exposure and its consequences is still missing. <b><i>Objective:</i></b> A systematic review and a meta-analysis were performed to provide an overview of neonatal withdrawal signs following late in utero exposure to SSRIs and to quantify the corresponding risks. <b><i>Methods:</i></b> MEDLINE, Web of Science, and Embase were searched from inception to January 2021. The Meta-Analysis of Obse

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42

Mann, Johannes F. E., Vivian A. Fonseca, Neil R. Poulter, Itamar Raz, Thomas Idorn, Søren Rasmussen, Bernt Johan von Scholten, and Ofri Mosenzon. "Safety of Liraglutide in Type 2 Diabetes and Chronic Kidney Disease." Clinical Journal of the American Society of Nephrology 15, no. 4 (March 4, 2020): 465–73. http://dx.doi.org/10.2215/cjn.11881019.

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Background and objectivesThe glucagon-like peptide-1 receptor agonist liraglutide demonstrated cardiovascular and kidney benefits in the LEADER trial, particularly in participants with CKD.Design, setting, participants, & measurementsThis post hoc analysis evaluated the safety of liraglutide treatment in patients with CKD in LEADER. Overall, 9340 patients were randomized to liraglutide or placebo, both in addition to standard of care. Of those, 2158 patients had CKD versus 7182 without CKD (defined as eGFR <60 versus ≥60 ml/min per 1.73 m2, respectively); 966 patients had macroalbuminur

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Yan, J., K. Gushulak, M. Columbus, A. Hamelin, and I. G. Stiell. "P144: Sentinel visits in emergency department patients with diabetes mellitus as a warning sign for hyperglycemic emergencies." CJEM 18, S1 (May 2016): S126. http://dx.doi.org/10.1017/cem.2016.318.

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Introduction: Patients with poorly controlled diabetes mellitus (DM) often visit the emergency department (ED) for management of hyperglycemia, diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). Many of these patients have a “sentinel” ED visit for other medical conditions prior to their hyperglycemic visit, which may worsen their glucose control. The objective of this study was to describe the epidemiology and outcomes of patients presenting with a sentinel ED visit prior to their visit for a hyperglycemic emergency. Methods: This was a health records review of patients ≥

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McClintock, H. F., and H. R. Bogner. "An Intervention Addressing Social Determinants and Oral Hypoglycemic Medication Adherence." Annals of Epidemiology 49 (September 2020): 77. http://dx.doi.org/10.1016/j.annepidem.2020.05.026.

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Gomes, Tara, David N. Juurlink, Lorraine L. Lipscombe, and Muhammad M. Mamdani. "Clinical and demographic characteristics of patients receiving different oral hypoglycemic agents." Pharmacoepidemiology and Drug Safety 18, no. 8 (August 2009): 756–60. http://dx.doi.org/10.1002/pds.1750.

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Cohen, M. Michael. "Beckwith-Wiedemann Syndrome: Historical, Clinicopathological, and Etiopathogenetic Perspectives." Pediatric and Developmental Pathology 8, no. 3 (May 2005): 287–304. http://dx.doi.org/10.1007/s10024-005-1154-9.

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Macroglossia, prenatal or postnatal overgrowth, and abdominal wall defects (omphalocele, umbilical hernia, or diastasis recti) permit early recognition of Beckwith-Wiedemann syndrome. Complications include neonatal hypoglycemia and an increased risk for Wilms tumor, adrenal cortical carcinoma, hepatoblastoma, rhabdomyosarcoma, and neuroblastoma, among others. Perinatal mortality can result from complications of prematurity, pronounced macroglossia, and rarely cardiomyopathy. The molecular basis of Beckwith-Wiedemann syndrome is complex, involving deregulation of imprinted genes found in 2 doma

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Klein, B. E. K., R. Klein, and S. E. Moss. "Risk of Hypoglycemia in Users of Human Insulin: The Wisconsin Epidemiologic Study of Diabetic Retinopathy." Diabetes Care 20, no. 3 (March 1, 1997): 336–39. http://dx.doi.org/10.2337/diacare.20.3.336.

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Hadler, Nortin M. "Oral Hypoglycemics and Diabetic Nephropathy." Clinical Journal of the American Society of Nephrology 3, no. 1 (January 2008): 159–62. http://dx.doi.org/10.2215/cjn.03730907.

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Amin, Sunil, Grace Mhango, Jenny J. Lin, Anne Aronson, Paolo Boffetta, Juan P. Wisnivesky, and Aimee Lucas. "Effect of metformin on survival in pancreatic ductal adenocarcinoma." Journal of Clinical Oncology 34, no. 4_suppl (February 1, 2016): 383. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.383.

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383 Background: Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal. Diabetes mellitus (DM) is both a risk factor for and a sequela of PDAC. Metformin, a commonly prescribed biguanide oral hypoglycemic used for the treatment of type II DM, has been found to have a chemo-protective role in PDAC in some in-vitro and human-based studies; conflicting literature exists regarding its potential role as a therapeutic agent. We investigated whether metformin use prior to PDAC diagnosis is associated with improved survival of patients with DM. Methods: We used the Surveillance, Epidemiology, a

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Limanova, O. A., L. E. Fedotova, and O. A. Gromova. "Combined oral contraceptives and treatment of new coronavirus infection (COVID-19): aspects of drug interactions." Infekcionnye bolezni 19, no. 1 (2021): 149–58. http://dx.doi.org/10.20953/1729-9225-2021-1-149-158.

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This article discusses the problem of drug interactions between combined oral contraceptives on the example of Belara® (30 μg of ethinyl estradiol + 2 mg of chlormadinone acetate; Gedeon Richter, Hungary) and medications recommended for the treatment of new coronavirus infection (COVID-19) and concomitant disorders at the pharmacodynamic and pharmacokinetic levels with an assessment of the efficacy and safety of therapy for females. We described safe, potentially dangerous, and dangerous combinations of these drugs. Key words: new coronavirus infection (CAVID-19), combined oral contraceptives,

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