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Rozprawy doktorskie na temat „Immunisation”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Leask, J. "Understanding Immunisation Controversies." Thesis, The University of Sydney, 2002. http://hdl.handle.net/2123/12503.

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BACKGROUND: Mass childhood vaccination has had a profound impact on reducing morbidity and mortality from a number of infectious diseases. Ironically, as vaccine preventable diseases become less common and so less visible to the public, greater attention is afforded to vaccine risks. In the UK, Japan, France and the USA, controversies about the safety of vaccines have led to declining public confidence in the practice which, at times, has lowered immunisation rates, leading to disease outbreaks and deaths. Public health workers are often perplexed at how to respond in such situations. In order

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2

Jones, Megan. "Immunisation : a discourse analytic study /." Title page, abstract and contents only, 1998. http://web4.library.adelaide.edu.au/theses/09PM/09pmj78.pdf.

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3

Clegg, Andrew J. "Childhood immunisation uptake : geographical perspectives." Thesis, University of Portsmouth, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332849.

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Efforts to control and eradicate infectious disease have concentrated on the provision of childhood vaccination. Unfortunately, the uptake of childhood vaccination continues to vary and infectious diseases continue to cause differential morbidity and mortality. Limited research has assessed the factors that underlie the uptake of vaccination. The present research undertakes an analysis of the patterns and determinants of vaccination uptake within the Portsmouth and South East Hampshire Health Authority, located in the south of England. In so doing, the research employs different analytical app

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4

Carpenter, Zoe Karen. "Novel immunisation strategies against Salmonella." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/13319.

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This thesis presents two novel immunisation strategies against <i>Salmonella enterica</i> serovar Typhimurium (<i>S. typhimurium</i>) in the mouse model. Firstly, mice immunised with multiple antigens in the form of a DNA vaccine have been shown to develop specific humoral and cellular responses to proteins encoded within the vaccine. Secondly, it has been shown that immunisation with multiple cytosolic antigens (CA) of <i>S. typhimurium </i>SL1344, formulated with the adjuvant dimethyl dioctadecyl ammoniumbromide (DDA), induces strong humoral and cellular responses. These responses have been

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5

CHABANNIER, MARIE-HELENE. "Immunisation anti-okt3 : aspects methodologiques." Toulouse 3, 1994. http://www.theses.fr/1994TOU31569.

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6

Scholz, Kirsten [Verfasser]. "New immunisation strategies via mucosal routes : comparative analysis of sublingual, intravaginal and intranasal immunisation / Kirsten Scholz." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2012. http://d-nb.info/1026933870/34.

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7

Harvey, Hannah Louise. "The role of the care-giver in infant immunisation : influences and perspectives on immunisation uptake and pain expression." Thesis, Durham University, 2016. http://etheses.dur.ac.uk/11427/.

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The recent decline in early childhood vaccination has been attributed to negative parental attitudes about immunisation. Vaccinations are a common cause of acute infant pain, although the impact of infant pain expression upon vaccination uptake is not well understood. Theoretical models of infant pain propose that care-giver behaviours may regulate pain expression, although previous findings have been inconclusive. Understanding care-giver beliefs, and the relationship between care-giver and infant behaviours during immunisation, may help to identify effective soothing strategies and develop i

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8

Tadich, N. A. "Studies on immunisation of ewes and lambs." Thesis, University of Liverpool, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370843.

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9

Dahlan, Afendi. "Needle-less skin immunisation using low-frequency ultrasound." Thesis, University College London (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520745.

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10

Gould, Myles I. "Multilevel modelling of geographical variations in immunisation uptake." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296694.

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11

Forster, A. S. "The human papillomavirus immunisation programme and sexual behaviour." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1301995/.

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The introduction of human papillomavirus (HPV) vaccination has caused some parents to report concern that their daughters may change their sexual behaviour following vaccination. This concern consistently relates to vaccination acceptance, but had not been investigated in detail. Accordingly, five studies addressed the thesis objective: to explore parents’ concern about adolescent sexual behaviour following HPV vaccination in the context of the UK immunisation programme and to examine whether such concerns were justifiable. The first study examined discussions of risky sexual behaviour and HPV

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12

Johnston, Louise. "Transcutaneous immunisation with antigens derived from tetanus toxin." Thesis, Imperial College London, 2008. http://hdl.handle.net/10044/1/4657.

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Transcutaneous immunisation (TCI) is a novel needle-free method of vaccine delivery, which involves the application of soluble antigens onto the surface of intact skin. In this thesis, the immunogenicity and neutralising potency of tetanus neurotoxin (TeNT) fragments were compared to that of tetanus toxoid (TTxd) following TCI. In addition, to understand the mechanisms of induction of immune response by TCI, in vitro and in vivo interaction of tetanus proteins with skin immune cells was also investigated. The 50kDa recombinant carboxyl-terminal fragment of tetanus toxin (HCWT) and a 50kDa HC m

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13

Gallagher, J. D. "Gregarious immunisation in the mealworm beetle, Tenebrio molitor." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/12275/.

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Investment in immunity is costly: one way in which hosts can ameliorate these costs is through immune priming, whereby hosts develop increased protection to future infection following previous exposure to a parasite or immune elicitor. Priming offers hosts a more efficient way of managing immune insult by allowing for a stronger and faster response to an immune insult. As well as investing in physiological immune defences, hosts can also leverage behavioural responses to reduce the costs of infection. Group-living in insects offers several benefits, such as predator avoidance. However, it can

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14

Nattes, Tristan de. "Rejet humoral d'allogreffe rénale et allo-immunisation HLA." Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMR053.

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La transplantation rénale est le meilleur traitement de l’insuffisance rénale chronique terminale, que ce soit en termes d’espérance ou de qualité de vie. Malgré les progrès réalisés en immunologie de la transplantation et dans la gestion globale des patients transplantés, la principale étiologie de perte de greffon reste le rejet, et en particulier le rejet humoral.L’évaluation du risque de rejet humoral repose principalement sur le dosage des anticorps anti-HLA dirigés contre le greffon. Pourtant, il apparait que ces anticorps ont un faible pouvoir prédictif de l’incidence et du pronostic du

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15

Elayeb, Rahma. "Étude des mécanismes de l'allo-immunisation post-transfusionnelle." Thesis, Paris Est, 2016. http://www.theses.fr/2016PESC0076.

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La transfusion sanguine est un traitement essentiel à la survie de millions de patients. Son principal risque immunologique est l’allo-immunisation post-transfusionnelle. Elle se traduit par la production d’allo-anticorps contre des antigènes de globules rouges (GR) conduisant à des hémolyses post-transfusionnelles. Les mécanismes à l’origine de la tolérance des GR ou de son inhibition lors de l’allo-immunisation sont mal connus. Ainsi, mes travaux de thèse, portant sur la compréhension de ces effets, se sont articulés en trois parties avec 1/ l’étude des conditions optimales aux réponses allo

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16

Elayeb, Rahma. "Étude des mécanismes de l'allo-immunisation post-transfusionnelle." Electronic Thesis or Diss., Paris Est, 2016. http://www.theses.fr/2016PESC0076.

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La transfusion sanguine est un traitement essentiel à la survie de millions de patients. Son principal risque immunologique est l’allo-immunisation post-transfusionnelle. Elle se traduit par la production d’allo-anticorps contre des antigènes de globules rouges (GR) conduisant à des hémolyses post-transfusionnelles. Les mécanismes à l’origine de la tolérance des GR ou de son inhibition lors de l’allo-immunisation sont mal connus. Ainsi, mes travaux de thèse, portant sur la compréhension de ces effets, se sont articulés en trois parties avec 1/ l’étude des conditions optimales aux réponses allo

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17

Casswall, Thomas. "Passive immunisation as therapy for gastrointestinal infections in children /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3862-8/.

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18

Al-Jabban, T. M. T. "Factors influencing immunisation uptake in childhood in Saudi Arabia." Thesis, Swansea University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.635685.

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The present research aims to study the postnatal care services in Saudi Arabia. It is designed to determine the factors that influence the pattern of immunisation uptake in childhood at immunisation clinics in Primary Health Care Centres (PHCCs) in the Madinah Area. The study covers the Madinah Area (Western Region), which showed, according to published MOH reports, the lowest immunisation coverage by all vaccines (Farag et al., 1995). A survey study of 503 children (1006 Parents), representing 6% of the total study population, was conducted in 24 PHC Centres, which represent 30% of the total

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19

Cahill, Edward Sean. "Antigen delivery systems for nasal immunisation against B. pertussis." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321455.

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20

Scott, Susana. "The impact of HIV on measles and measles immunisation." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439504.

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21

Zuckerman, Jane Nicola. "Prevention of viral hepatitis A and B by immunisation." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336638.

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22

Tan, Tiong Kit. "Development of viral vectors for passive immunisation against influenza." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:54fd7396-f09a-46e5-952e-95a1f5449326.

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Seasonal influenza is a major global health threat causing more than 500,000 deaths annually. Pandemic influenza can arise through antigenic shift, or when novel influenza strains escape from animal reservoirs, and can affect a large geographical area leading to a large number of deaths. Neither prior infection, nor current vaccines, provide lasting protection due to the rapid antigenic evolution of influenza virus. The discovery of broadly neutralising antibodies (bnAbs) against influenza has opened the possibility of passive immunisation, which could provide protection against multiple influ

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23

Al, Sebea Hussain. "Dynamic detection and immunisation of malware using mobile agents." Thesis, Edinburgh Napier University, 2005. http://researchrepository.napier.ac.uk/output/4036/.

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At present, malicious software (mal-ware) is causing many problems on private networks and the Internet. One major cause of this includes outdated or absent security software to countermeasure these anomalies such as Antivirus software and Personal Firewalls. Another cause is that mal-ware can exploit weaknesses in software, notably operating systems. This can be reduced by use of a patch service, which automatically downloads patches to its clients. Unfortunately this can lead to new problems introduced by the patch server itself. The aim of this project is to produce a more flexible approach

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24

Abdullahi, Leila Hussein. "Adolescent immunisation in Africa in the decade of vaccines." Doctoral thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/30364.

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Rationale: There are many public health benefits of targeting adolescent for immunisation. However, and in many settings, adolescents do not get optimal benefits from immunisation. In the decade of vaccines (2011-2020), adolescent immunisation is a topical subject. An up-to-date and synthesized research on adolescent immunisation is lacking. Overall purpose: The purpose of the PhD thesis was to characterize adolescent immunisation in the decade of vaccines. Research methods: First, we conducted a comprehensive narrative review of the literature (chapter 2) on adolescent immunisation. Then, we

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25

Wiysonge, Shey Umaru Charles. "Building evidence for improving childhood immunisation coverage in Africa." Doctoral thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/3183.

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Includes abstract.<br>Includes bibliographical references.<br>The Expanded Programme on Immunisation has the potential to substantially reduce child mortality and contribute to achieving the Millennium Development Goals. We assessed the programme’s performance in Africa, the reasons for poor performance, and effective interventions for improving its performance on the continent. We used a combination of methods including systematic reviews, bibliometric analyses, generalised linear models, and grading of the quality of evidence. We found that African countries have made extraordinary advances

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26

Chavarin, Notin Patricia. "A propos d'un cas d'allo-immunisation foeto-maternelle plaquettaire." Saint-Etienne, 1993. http://www.theses.fr/1993STET6201.

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27

Kimera, Sharadhuli I. "Methods for the design and evaluation of East Coast fever (ECF) control strategies." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242338.

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28

Borus, Peter Kimutai. "Measles vaccination in Kenya : determination of vaccine coverage, determinants of receipt of vaccination and the quality of immunisation services in slum areas of Nairobi." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289764.

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29

Bonnet, Françoise. "Allo-immunisation foeto-maternelle dans le systeme rhesus : proposition d'un score predictif de l'atteinte foetale." Toulouse 3, 1988. http://www.theses.fr/1988TOU31037.

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30

Schöneck, Ralf. "Clonage et caractérisation moléculaire d'un ADNc de trypanosoma cruzi codant pour une protéine homologue aux glutathion s-transferases : approche fonctionnelle." Lille 1, 1994. http://www.theses.fr/1994LIL10044.

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Au cours de ce travail, nous avons clone et caracterise une adnc (tcac2) de trypanosoma cruzi qui code pour une proteine homologue aux proteines de stress de faible poids moleculaire et aux glutathion s-transferases. Cette homologie de sequence a ete renforcee par des analyses comparatives des profiles d'hydropathie et des structures secondaires (hca). De plus, la proteine native correspondante du stade epimastigote a ete purifiee sur une colonne d'affinite avec le s-hexylglutathion comme matrice et sequencee directement afin de prouver l'identite. Un serum dirige contre la proteine de fusion

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31

Dinan, Leonie Rita. "Antibody responses after Hib immunisation in premature and term infants /." Title page, table of contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09MPM/09mpmd583.pdf.

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32

Creusot, Remi Jerome. "Particle-mediated DNA immunisation : CD+T cell priming and cooperation." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399172.

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33

Laing, Gavin. "The use of liposomes for immunisation against Echis carinatus venom." Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317199.

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34

Mcshane, Helen Irene. "Immunisation strategies for enhancing T cell responses against M. tuberculosis." Thesis, University of London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271722.

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35

Dhanoya, A. S. "Characterisation of plasmid DNA complexes for application in genetic immunisation." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1357937/.

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Non-viral gene delivery into mammalian cells is widely used in bio-processing for the production of recombinant proteins as well as considered for clinical trials in gene therapy and vaccination. DNA can be delivered through various non-viral methods including polymers, lipids, peptides and entrapment within nanoparticles. Non-viral gene delivery often entails nucleic acids that are bound to a polymer or polycation to form a complex referred to as polyplexes. Various factors may affect the efficiency of polyplex uptake in mammalian cells. One factor is DNA topology, which is important from a r

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36

Matthews, Zoe. "Child immunisation programmes in developing countries : assessing the demographic impact." Thesis, University of Southampton, 1993. https://eprints.soton.ac.uk/34278/.

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37

Corrigall, Joanne. "Immunisation coverage of the Western Cape Province : household survey 2005." Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/9318.

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Includes bibliographical references.<br>[Objective] To determine the routine immunisation coverage rates in children aged 12-23 months in the Western Cape and factors affecting immunisation coverage. [Design] Cross-sectional Household Survey using an adaptation of the '30x7' cluster survey technique (multi-stage sampling). [Setting] Households across the Western Cape. [Subjects] 3705 caregivers of children aged 12-23 months who had been living in the Western Cape for at least 6 months. [Outcome Measures] Vaccination Status (1=fully vaccinated, 0=partially vaccinated) as recorded on a Road to H

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38

RIPOLL, PATTE CHRISTINE. "Allo-immunisation plaquettaire foeto-maternelle : a propos d'une famille informative." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20348.

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39

Harrop, Jeremy Alexander. "The role of natural killer cells in respiratory syncytial virus infection of BALB/c mice." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287417.

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40

Tamizifar, Hassan. "Enhancement of subunit influenza vaccine with diptheria - tetanus - pertussis (DTP) vaccination." Thesis, University of Sheffield, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388739.

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41

Berry, P. R. "Production of monoclonal antibodies to Bordetella pertussis as a means of identifying protective antigens." Thesis, University of Reading, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376819.

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42

Perrie, Yvonne. "Liposomes as a gene delivery system." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312844.

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43

Stagg, A. J. "Characterisation of the immune response of mice to Mycobacterium leprae." Thesis, University College London (University of London), 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380659.

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44

Lam, Shang Leen Clifford. "Plasma procurement and clinical evaluation of an intravenous immunoglobulin preparation." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/19028.

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45

Genin, Christian. "Étude des facteurs favorisant les dépôts glomérulaires d'immunoglobulines chez la souris : effet de la charge de l'antigène : effet de l'immunisation orale dans la souche C3H/HeJ." Lyon 1, 1986. http://www.theses.fr/1986LYO1H060.

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Murphy, Catherine Estelle. "Conditions for sustainability in the Global Alliance for Vaccines and Immunisation." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417379.

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47

Ribeiro, Suzie Jesus. "A study of DNA/Dendron nanoparticles for genetic immunisation against anthrax." Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439784.

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Chigwenah, Tariro. "Explaining the socio-economic inequalities in child immunisation coverage in Zimbabwe." Master's thesis, University of Cape Town, 2020. http://hdl.handle.net/11427/32533.

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Socioeconomic inequalities in health have received significant attention globally because of the well-known association between wealth and health. A lot of studies show that poor people are more prone to sickness than their counterparts. Immunisation has been a key antidote to avert deaths for children under the age of 5. This study represents an initial attempt to assess specific variables that contribute to socioeconomic inequalities in immunisation coverage in Zimbabwe. Data were obtained from the 2015 Zimbabwe Demographic Health Survey, a nationally representative survey. Immunisation cove

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49

DEVILLERS, HERVE. "L'exsanguino-transfusion in utero dans l'allo-immunisation foeto-maternelle anti-d." Amiens, 1992. http://www.theses.fr/1992AMIEM082.

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50

Joseph, Telphia-Leanne. "An investigation into how Aboriginal Medical Services contribute to childhood immunisation." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/12550.

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While there are diverse immunisation service providers, according to the Australian Childhood Immunisation Register (ACIR), less than 1% of all childhood vaccinations (equating to less than 10% of all Aboriginal children) are recorded as being delivered by an Aboriginal Medical Service (AMS). This is likely to be an under-estimate of the care provided. This study sought to determine to what extent AMS’s contribute to the immunisation of Aboriginal children in their local areas. Results The findings revealed that AMS’s in NSW are taking active steps to achieve an improvement in coverage and tim

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