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1

Samorodnova, Elena A. "Iron deficiency in children: modern aspects of the problem, possibilities of primary prevention: A review." Pediatrics. Consilium Medicum, no. 4 (January 18, 2023): 302–8. http://dx.doi.org/10.26442/26586630.2022.4.201960.

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Iron deficiency (ID) is common in the pediatric population, primarily due to inadequate iron intake from food and a high requirement due to rapid growth. The most significant for pediatric practice are latent iron deficiency and iron deficiency anemia. Hyposiderosis significantly impacts a child's physical and cognitive development and immunological reactivity. It can be an independent condition and complicate the course of several other diseases. The article presents data on the most significant factors contributing to the ID, risk groups, clinical presentation features (sideropenic and anemi
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Khan, Saadia, Imran Iqbal, Asad Abbas, Reema Arshad, Ibad Ali, Sabeeha Khan, and Adan Ijaz. "Parental Iron Therapy to Treat Iron Deficiency Anemia in Malnourished Children." Journal of Islamic International Medical College 17, no. 4 (December 29, 2022): 239–44. http://dx.doi.org/10.57234/691.

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Objective: To evaluate the safety and efficacy of parental iron therapy to treat iron deficiency anemia in malnourished children. Study Design: Quasi experimental design. Place and Duration of Study: Stabilization Centre, Children Hospital and the Institute of Child Health, Multan from 1 December 2014 to 31 December 2020. Materials and Methods: A total of 250 malnourished children with iron deficiency were included in the study. The laboratory parameters i.e., Hemoglobin, Hematocrit, Red Blood Cells Count, mean corpuscular hemoglobin, mean corpuscular volume, and Serum ferritin of all patients
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Lakkaraja, Madhavi, Lesley Small, Maura Frank, Aliza Solomon, Nicole Kucine, and James B. Bussel. "Iron Deficiency Anemia in Infants and Toddlers – Role of Milk and Constipation." Blood 120, no. 21 (November 16, 2012): 5171. http://dx.doi.org/10.1182/blood.v120.21.5171.5171.

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Abstract Abstract 5171 Introduction: One of the most common nutritional deficiencies in the world is iron-deficiency anemia and young children are at high risk of developing it. In spite of fortification of foods in the United States, there is a high prevalence of anemia in infants and toddlers increasing their risk of neuro-developmental effects. Constipation is defined as delay or difficulty in defecation ≥ 2 weeks. Around one year of age, various changes are commonly implemented in a child's diet including introduction of whole milk and solids. Children may then present with sub-clinical co
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Kazancı, Elif Güler, Muhammet Furkan Korkmaz, and Betül Orhaner. "Efficacy and safety of intravenous iron sucrose treatment in children with iron deficiency anemia." Medical Science and Discovery 6, no. 10 (October 27, 2019): 278–83. http://dx.doi.org/10.36472/msd.v6i10.317.

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Objective: The purpose of this study is to investigate the efficacy and safety of intravenous iron sucrose treatment in children with iron deficiency anemia who were unresponsive to or could not tolerate oral iron therapy.
 Material and Methods: Among patients determined to have iron deficiency anemia, and were intolerant or noncompliant with oral iron therapy, 92 patients who have received parenteral iron therapy between the ages of 6 months and 18 years have been investigated retrospectively. Age, gender, patient complaints at application, dietary characteristics, accompanying diseases
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Moscheo, Carla, Elisa Fenizia, Mariaclaudia Meli, and Giovanna Russo. "Anemia sideropenica in età pediatrica: pillole di… ferro." QUADERNI ACP 28, no. 4 (2021): 173. http://dx.doi.org/10.53141/qacp.2021.176-180.

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Iron deficiency anemia is the most frequent haematological disorder in children. Although much is already known about the diagnostic-therapeutic approach, new frontiers regarding its diagnosis and therapeutic options emerge every day. An adequate intake with the diet is essential and can also be obtained in compliance with vegetarian-type diets. The use of glycinate or lysosomal preparations could positively affect the efficacy of therapy reducing the side effects associated with commonly used iron preparations. Parenteral iron therapy in pediatric age, which is currently limited to selected c
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6

Daniel, Catherine, Ellen S. Plummer, and George R. Buchanan. "Deficiencies in the Management of Iron Deficiency Anemia During Childhood." Blood 118, no. 21 (November 18, 2011): 3154. http://dx.doi.org/10.1182/blood.v118.21.3154.3154.

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Abstract Abstract 3154 Background: Iron deficiency anemia (IDA) is a common hematologic problem worldwide, potentially leading to cognitive delays, fatigue, seizures, and, when severe, high output heart failure. While IDA frequently is encountered in both the primary care setting and specialty clinics, its management is not evidence based. As a result, the diagnosis and treatment of IDA is often suboptimal. To help inform future clinical trials, we retrospectively characterized the clinical course of IDA in young patients (pts) referred to our center. Methods: Using our comprehensive hematolog
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7

Powers, Jacquelyn M., Timothy L. Mccavit, Leah Adix, and George R. Buchanan. "Low Dose Once Daily Oral Iron Treatment of Young Children with Nutritional Iron Deficiency Anemia." Blood 126, no. 23 (December 3, 2015): 2147. http://dx.doi.org/10.1182/blood.v126.23.2147.2147.

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Abstract Background Iron deficiency anemia (IDA) is prevalent in young children whose diet includes prolonged breast feeding without iron supplementation and/or excessive cow milk consumption. Oral iron therapy is recommended to correct the anemia and reconstitute iron stores, but few data exist to guide clinical decision-making. The recommended dosing of elemental iron has been inconsistent in the literature, ranging from 2 to 6 mg/kg/day, given one to three times daily. To address the paucity of treatment data, the BESTIRON study (Clinicaltrials.gov NCT01904864) was initiated to compare two
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8

Nestor, Jennifer A., Faraz A. Afridi, Richard Suarez, Joey Bou Karem, Michael Hardiman, Krystal Hunter, Christine Rickette, and Rafat Ahmed. "Intravenous Iron Infusions in Pediatric Patients: A Single Institution Assessment of Efficacy and Adverse Effects of IV Iron Infusions." Blood 134, Supplement_1 (November 13, 2019): 5872. http://dx.doi.org/10.1182/blood-2019-123800.

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Background: Iron deficiency, even without a diagnosis of anemia, can be neurodevelopmentally dangerous in pediatric populations. Oral iron supplementation has been the treatment of choice but is associated with poor adherence for several reasons including metallic taste of the tablets, gastric irritation, severe constipation, and daily dosing for several weeks. Intravenous iron has been safely used in adult populations for iron supplementation, but has less commonly been used in pediatric populations. It is hypothesized that pediatric patients with iron deficiency anemia (IDA) who receive intr
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9

Garg, Shipra, Narry Savage, Emmanuel Siaw, and Ashish Patel. "Ménétrier Disease; 2-Year-Old Boy Presenting With Prolonged Emesis, Generalized Edema and Chance Histopathological Finding of Cytomegalovirus Gastritis: A Case Report." Archives of Medical Case Reports and Case Study 4, no. 2 (May 12, 2021): 01–04. http://dx.doi.org/10.31579/2692-9392/029.

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Ménétrier disease (MD) is characterized by enlarged gastric folds with associated protein losing gastropathy. In children it is a rare and self-limited cause of protein losing gastropathy. We report a case of a 2-year-old male who presented with prolonged, refractory emesis and peripheral edema. Workup revealed severe hypoalbuminemia, hypoproteinemia, iron deficiency anemia, and high stool alpha-1 antitrypsin. Hepatic protein synthesis was normal with no urinary protein loss. Endoscopy showed antrum sparing, severe erosive gastritis in body and fundus, characteristic of MD. Histologic examinat
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10

Garg, Shipra. "Ménétrier Disease; 2-Year-Old Boy Presenting With Prolonged Emesis, Generalized Edema and Chance Histopathological Finding of Cytomegalovirus Gastritis: A Case Report." Archives of Medical Case Reports and Case Study 4, no. 2 (May 12, 2021): 01–05. http://dx.doi.org/10.31579/2694-0248/029.

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Ménétrier disease (MD) is characterized by enlarged gastric folds with associated protein losing gastropathy. In children it is a rare and self-limited cause of protein losing gastropathy. We report a case of a 2-year-old male who presented with prolonged, refractory emesis and peripheral edema. Workup revealed severe hypoalbuminemia, hypoproteinemia, iron deficiency anemia, and high stool alpha-1 antitrypsin. Hepatic protein synthesis was normal with no urinary protein loss. Endoscopy showed antrum sparing, severe erosive gastritis in body and fundus, characteristic of MD. Histologic examinat
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11

Landry, Carmen, Jon Dorling, Ketan Kulkarni, Marsha Campbell-Yeo, Michael Vincer, Joyce Ledwidge, Lisa Morrison, and Satvinder Ghotra. "Risk Factors for Iron Deficiency in Very Preterm Infants at 4-6 Months Corrected Age." Blood 136, Supplement 1 (November 5, 2020): 28. http://dx.doi.org/10.1182/blood-2020-142442.

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Background: Iron is an essential micronutrient, especially in infants and young children and is required for erythropoiesis and development of the central nervous system. However, iron deficiency (ID) is the most common micronutrient deficiency worldwide. ID and iron deficiency anemia (IDA) have been associated with poor neurodevelopmental and behavioural outcomes later in life. Preterm infants are particularly at risk of developing ID in early life due to lower iron stores at birth, accelerated growth in the first weeks of life and multiple phlebotomies while in hospital. Therefore, internati
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12

Roganović, Jelena. "PARENTERAL IRON THERAPY IN CHILDREN WITH IRON DEFICIENCY ANEMIA." Paediatrics Today 11, no. 1 (March 15, 2015): 24–29. http://dx.doi.org/10.5457/p2005-114.106.

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Roganovic, Jelena, and Elpis Mantadakis. "Parenteral iron therapy in children with iron deficiency anemia." World Journal of Pediatrics 12, no. 1 (January 19, 2016): 122–23. http://dx.doi.org/10.1007/s12519-016-0002-5.

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AHMED, SHAHEEN, Salman Ali, NAEEM FAREED, Mehboob Sultan, NADEEM SADIQ, and Umar Khurshid. "IRON DEFICIENCY ANEMIA." Professional Medical Journal 16, no. 02 (June 10, 2009): 209–15. http://dx.doi.org/10.29309/tpmj/2009.16.02.2903.

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t r o d u c t i o n : The adherence to treatment of iron deficiency anemia often is poor in both developed and developingcountries. The current standard therapy is oral ferrous sulfate administered 3 times daily. It is possible that adherence would improve witha single-dose daily treatment regimen. O b j e c t i v e s : To compare single versus thrice daily ferrous sulfate for treatment of iron deficiencyanemia in young children. D e s i g n : Quasi experimental study Setting: Children Department Military Hospital Rawalpindi. P e r i o d : From (01Jan- to31 Mar 05 and 03 Jul to 02 Oct 05) Subj
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15

Gordeuk, VR, GM Brittenham, CE McLaren, MA Hughes, and LJ Keating. "Carbonyl iron therapy for iron deficiency anemia." Blood 67, no. 3 (March 1, 1986): 745–52. http://dx.doi.org/10.1182/blood.v67.3.745.745.

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Abstract To determine if elemental carbonyl iron powder is safe and effective therapy for iron deficiency anemia, 20 nonanemic and 32 anemic volunteers were studied. Single doses of 1,000 to 10,000 mg of carbonyl iron (15 to 150 times the 65 mg of iron in the usual dose of ferrous sulfate) were tolerated by nonanemic volunteers with no evidence of toxicity and only minor gastrointestinal side effects. Anemic volunteers (menstruating women who had previously donated blood) were treated with several regimens providing 1,000 to 3,000 mg of carbonyl iron daily in one to three doses for 8 to 28 day
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16

Gordeuk, VR, GM Brittenham, CE McLaren, MA Hughes, and LJ Keating. "Carbonyl iron therapy for iron deficiency anemia." Blood 67, no. 3 (March 1, 1986): 745–52. http://dx.doi.org/10.1182/blood.v67.3.745.bloodjournal673745.

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To determine if elemental carbonyl iron powder is safe and effective therapy for iron deficiency anemia, 20 nonanemic and 32 anemic volunteers were studied. Single doses of 1,000 to 10,000 mg of carbonyl iron (15 to 150 times the 65 mg of iron in the usual dose of ferrous sulfate) were tolerated by nonanemic volunteers with no evidence of toxicity and only minor gastrointestinal side effects. Anemic volunteers (menstruating women who had previously donated blood) were treated with several regimens providing 1,000 to 3,000 mg of carbonyl iron daily in one to three doses for 8 to 28 days. After
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17

Boutry, Mireille, and Robert Needlman. "Use of Diet History in the Screening of Iron Deficiency." Pediatrics 98, no. 6 (December 1, 1996): 1138–42. http://dx.doi.org/10.1542/peds.98.6.1138.

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Objective. To determine the relationship between diet history and microcytic anemia, a proxy for iron deficiency, and the utility of a brief dietary history in screening for microcytic anemia. Design. Cross-sectional study based on review of clinical records. Setting. Urban academic primary care clinic. Subjects. A total of 305 healthy, African-American inner-city children, presenting for well child care at 15 to 60 months of age. Children with recent minor illness or medicinal iron intake, hemoglobinopathies, chronic illnesses, failure to thrive, or elevated lead levels were excluded. Method.
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18

Nazir, Fahad, Asim Khurshid, and Muhammad Abu Talib. "Intravenous iron sucrose in malnourished children with iron deficiency anemia." Professional Medical Journal 27, no. 09 (September 10, 2020): 1867–71. http://dx.doi.org/10.29309/tpmj/2020.27.09.4107.

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Objectives: To compare the mean hemoglobin level before and six weeks after giving intravenous iron sucrose therapy in malnourished children having iron deficiency anemia. Study Design: Quasi Experimental Study. Setting: Nutritional Stabilization Centre, Children Hospital and Institute of Child Health, Multan. Period: From July 2018 to December 2018. Material & Methods: A total of 80 patients were enrolled in the study. Hemoglobin level at baseline was recorded. IV iron sucrose therapy was divided into 3 equal doses and administered on 3 consecutive days. After 6 weeks of administration of
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19

Weiler, Hope A., Sonia Jean-Philippe, Tamara R. Cohen, Catherine A. Vanstone, and Sherry Agellon. "Depleted iron stores and iron deficiency anemia associated with reduced ferritin and hepcidin and elevated soluble transferrin receptors in a multiethnic group of preschool-age children." Applied Physiology, Nutrition, and Metabolism 40, no. 9 (September 2015): 887–94. http://dx.doi.org/10.1139/apnm-2014-0328.

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Iron deficiency anemia is prevalent in subgroups of the Canadian population. The objective of this study was to examine iron status and anemia in preschool-age children. Healthy children (n = 430, 2–5 years old, Montreal, Quebec, Canada) were sampled from randomly selected daycares. Anthropometry, demographics, and diet were assessed. Biochemistry included hemoglobin, ferritin, soluble transferrin receptors (sTfR), ferritin index, markers of inflammation (C-reactive protein, interleukin 6 (IL-6), and tumour necrosis factor alpha (TNFα)), and hepcidin. Iron deficiency and anemia cutoffs conform
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Graczykowska, Karolina, Joanna Kaczmarek, Dominika Wilczyńska, Ewa Łoś-Rycharska, and Aneta Krogulska. "The Consequence of Excessive Consumption of Cow’s Milk: Protein-Losing Enteropathy with Anasarca in the Course of Iron Deficiency Anemia—Case Reports and a Literature Review." Nutrients 13, no. 3 (March 3, 2021): 828. http://dx.doi.org/10.3390/nu13030828.

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Cow’s milk is a key component of a child’s diet. While the consumption of even trace amounts can result in allergy to its proteins and/or hypolactasia, excessive cow’s milk consumption can result in numerous health complications, including iron deficiency, due to the diet being improperly balanced. Although the incidence of iron deficiency has declined, it remains the most widespread nutritional deficiency globally and the most common cause of anemia. One rare consequence of anemia caused by iron deficiency is protein-losing enteropathy; however, the mechanisms of its development are unclear.
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Moningkey, Christie, Max F. J. Mantik, and Vivekenanda Pateda. "Ferric sodium edetate therapy in children with iron deficiency anemia." Paediatrica Indonesiana 55, no. 2 (April 30, 2015): 91. http://dx.doi.org/10.14238/pi55.2.2015.91-4.

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Background Iron deficiency anemia (IDA) is frequentlyfound in school-aged children. The main treatments for IDAare overcoming the causal factors and iron supplementation.Noncompliance in taking iron tablets and the possibility of ironabsorbtion or transport difficulties, can reduce efficacy of daily oraliron supplementation. Because excess iron storage in the intestinalcells can lead to mucosal blockage, twice weekly oral iron therapymay be considered instead of daily dosage.Objective To compare the effects of daily vs. twice weekly ferricsodium edetate (NaFeEDTA) on hemoglobin (Hb), hematocri
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Qader, Mohammed, and Abbas Rabaty. "Impact of iron deficiency anemia on HbA1c level in non-diabetic children." Zanco Journal of Medical Sciences 25, no. 3 (December 23, 2021): 619–24. http://dx.doi.org/10.15218/zjms.2021.027.

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Background and objective: HbA1c has been endorsed by the American Diabetes Association and World Health Organization to diagnose and monitor diabetes mellitus. Its value is directly proportional to the blood glucose level. However, besides the blood glucose level, other factors like iron deficiency anemia can affect HbA1c level. We conducted this study to reveal the impact of iron deficiency anemia on HbA1c level and to assess whether HbA1c result changes after the correction of iron deficiency anemia. Methods: Twenty five non-diabetic children who were confirmed to have iron deficiency anemia
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Kazi, Naheed Haroon, Roomana Qureshi, Tasneem Kousar, Ameena Saba, and Shabaz Ahmed Memon. "Factors Responsible for Iron Deficiency Anemia in Children Under Five Years." Pakistan Journal of Medical and Health Sciences 16, no. 1 (January 30, 2022): 1047–49. http://dx.doi.org/10.53350/pjmhs221611047.

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Objective: To determine the frequency of factors responsible for iron deficiency anemia in children under five years of age at tertiary care Hospital. Methodology: This cross-sectional study was done at the paediatric department of Muhammad Medical College MirpurKhas, during six months from October 2020 to March 2021. All the children with of (<5 years), presented at Paediatric OPD and of either gender were included. After taking complete clinical examination, parents were interviewed reading history of diet. After obtaining informed consent from the parents, a 3ml blood sample was taken fr
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Saragih, Rina A. C., T. Mirda Zulaicha, Sri Sofyani, Bidasari Lubis, and Iskandar Z. Lubis. "Behavior of elementary schoolchildren with iron deficiency anemia after iron therapy." Paediatrica Indonesiana 49, no. 5 (October 31, 2009): 276. http://dx.doi.org/10.14238/pi49.5.2009.276-80.

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Background Some studies had been performed to determine theassociation between iron status and children's behavior yet it isstill controversial.Objective To investigate whether iron therapy has an effect onthe behavior of children with iron deficiency anemia (IDA).Method A randomized placebo-controlled clinical trial wasconducted in Labuhan Batu on November 2006-April2007. IDAwas defined as Hb < 12 g/dl, MCHC< 31%, ROW index > 220and Mentzer index> 13. Elementary school children (6-12 yearsold) with IDA were randomly assigned to the treatment groupwith a daily therapy of 6 mg iron/
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Siqueira, Maria Clara Gonçalves, Lorrayne dos Santos Bezerra, Camila Zanini Gimenes de Freitas, Simone de Cássia Casadei Buchalla, and Sabrina Alves Lenquiste. "ASSOCIAÇÃO DO ESTADO NUTRICIONAL COM MARCADORES DE ANEMIA FERROPRIVA EM PRÉ-ESCOLARES ATENDIDOS EM UMAESF DE PRESIDENTE PRUDENTE-SP." Colloquium Vitae 12, no. 1 (March 9, 2020): 8–19. http://dx.doi.org/10.5747/cv.2020.v12.n1.v278.

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Iron deficiency is the cause of 50% of anemia cases, being related to an unbalanced diet and nutrient malabsorption, affecting mainly children. The aim of the present study was to relate anthropometric measurements and markers of iron deficiency anemia in children attending a Family Health Strategy (FHS). Information was collected from medical records about breastfeeding, biochemical indicators of anemia and recent anthropometric measurements. Correlation analyzes were established between anthropometric measurements and blood count values, considering a level of statistical significance of p&l
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26

Lyfia, Dina, Melda Deliana, Hakimi Hakimi, Nelly Rosdiana, and Bidasari Lubis. "Growth velocity in elementary school children with iron deficiency anemia after iron therapy." Paediatrica Indonesiana 49, no. 5 (October 31, 2009): 249. http://dx.doi.org/10.14238/pi49.5.2009.249-52.

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Background Iron supplementation in children with iron deficiencyanemia could decrease the incidence of stunting.Objective To study the effect of iron therapy on growth velocityin children with iron deficiency anemia.Methods A randomized clinical trial study was conducted atLabuhan Batu on November 2006 to May 2007. Iron deficiencyanemia was diagnosed if there were anemia, with mean corpuscular hemoglobin concentration <31 %, red cell distribution width index > 220, and Mentzer index> 13. Elementary school children (6-12 year old) with iron deficiency anemia were randomly assigned eith
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27

Husain, Arif, and Shrish Bhatnagar. "Does H. pylori therapy augments the effect of iron therapy among children with iron deficiency anemia?" International Journal of Contemporary Pediatrics 7, no. 4 (March 21, 2020): 831. http://dx.doi.org/10.18203/2349-3291.ijcp20201139.

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Background: To assess beneficial effects of H. pylori therapy on children with pre-existing Iron Deficiency Anemia (IDA).Methods: A total of 218 consecutive patients with iron deficiency anemia (Hb 6-11 gm/dl) were invited to participate in the study. Patients underwent endoscopic biopsy and rapid urease test for H. pylori detection. A total of three groups were formed- Group I (n=13) - positive for H. pylori, underwent treatment for H. pylori therapy and IDA, Group II (n=16) - positive for H. pylori, underwent treatment for IDA only, Group III (n=101) - negative for H. pylori, underwent treat
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28

Kapoh, Sabatika R., Linda W. A. Rotty, and Efata B. I. Polii. "Terapi Pemberian Besi pada Penderita Anemia Defisiensi Besi." e-CliniC 9, no. 2 (March 16, 2021): 311. http://dx.doi.org/10.35790/ecl.v9i2.32863.

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Abstract: Iron deficiency anemia (IDA) is caused by deficiency of iron needed for hemoglobin synthesis. Based on WHO data 2011, of 100% cases of patients with severe anemia, there were 50% of pregnant women, 49% of non-pregnant women, and 42% of children suffered from iron deficiency. Other literatures mentioned about 2-5% of adult men and post menopause women were diagnosed as iron deficiency anemia in developed countries. This study was aimed to determine the relationship between iron therapy in patients and iron deficiency anemia. This was a literature review study, summarizing the results
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29

Kucuk, Nuran, Zerrin Orbak, Cahit Karakelloglu, and Fatih Akcay. "The effect of therapy on plasma ghrelin and leptin levels, and appetite in children with iron deficiency anemia." Journal of Pediatric Endocrinology and Metabolism 32, no. 3 (March 26, 2019): 275–80. http://dx.doi.org/10.1515/jpem-2018-0352.

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Abstract Background It is known that iron deficiency anemia effects appetite and growth negatively. The aim of this study was to investigate the effect of iron therapy on appetite, growth and plasma ghrelin and leptin levels in children aged between 12 and 24 months with isolated nutritional iron deficiency anemia. Methods Iron deficiency anemia was diagnosed by clinic and laboratory findings. All 19 cases were given 5 mg/kg/day iron therapy for 3 months. Results The mean plasma ghrelin level was 936.7±428.8 pg/mL before therapy and it increased to 1284.7±533.3 pg/mL (p<0.001) while the mea
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Akin, Mehmet, Enver Atay, Osman Oztekin, Cem Karadeniz, Yasin Tugrul Karakus, Bilal Yilmaz, and Firat Erdogan. "Responsiveness to Parenteral Iron Therapy in Children with Oral Iron-Refractory Iron-Deficiency Anemia." Pediatric Hematology and Oncology 31, no. 1 (October 2, 2013): 57–61. http://dx.doi.org/10.3109/08880018.2013.829540.

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Powers, Jacquelyn M., Margaret Nagel, Jean L. Raphael, Donald H. Mahoney, George R. Buchanan, and Deborah I. Thompson. "Barriers to and Facilitators of Iron Therapy in Children with Iron Deficiency Anemia." Journal of Pediatrics 219 (April 2020): 202–8. http://dx.doi.org/10.1016/j.jpeds.2019.12.040.

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Camaschella, Clara. "Iron deficiency." Blood 133, no. 1 (January 3, 2019): 30–39. http://dx.doi.org/10.1182/blood-2018-05-815944.

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Abstract Iron deficiency anemia affects >1.2 billions individuals worldwide, and iron deficiency in the absence of anemia is even more frequent. Total-body (absolute) iron deficiency is caused by physiologically increased iron requirements in children, adolescents, young and pregnant women, by reduced iron intake, or by pathological defective absorption or chronic blood loss. Adaptation to iron deficiency at the tissue level is controlled by iron regulatory proteins to increase iron uptake and retention; at the systemic level, suppression of the iron hormone hepcidin increases iron rele
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Korol, T. G., K. V. Khromykh, H. M. Rudenko, and A. V. Bereznitskiy. "Scientific reviews. Principles of diagnosis and treatment of iron deficiency anemia in children." Reports of Vinnytsia National Medical University 25, no. 3 (September 23, 2021): 510–13. http://dx.doi.org/10.31393/reports-vnmedical-2021-25(3)-28.

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Annotation.In Europe, the overall prevalence of iron deficiency anemia is 2-4%, with two peaks: young children (2.3-15%) and adolescents (3.5-13% – in boys, 11-33% – in girls). Iron deficiency occurs earlier than anemia, which is characterized by a decrease in the size and iron saturation of erythrocytes, and they become microcytic and hypochromic. Therefore, anemia can be prevented by early diagnosis and treatment of latent iron deficiency. The aim of the work was to analyze and systematize the main problematic issues of diagnosis and treatment of iron deficiency anemia in children. To conduc
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Tiwari, Bharti, Amar Singh Tiwari, and Satish Chand Gupta. "AN AMELIORATE COMPARATIVE CLINICAL TRIAL OF NAVAYAS LOUHA SYRUP AND NISHA LOUHA SYRUP IN THE MANAGEMENT OF PANDU ROGA WITH SPECIAL REFERENCE TO IRON DEFICIENCY ANEMIA IN CHILDREN." International Journal of Research in Ayurveda and Pharmacy 12, no. 4 (August 28, 2021): 56–61. http://dx.doi.org/10.7897/2277-4343.1204106.

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Anemia is a major health problem in India. Yet, a comprehensive plan of action to combat this public health problem has been still missing. There are few existing plans for the control of Iron Deficiency Anemia regarding children and pregnant women and lactating mothers. Iron deficiency is the result of long-term negative iron balance. Iron deficiency anemia (IDA) should be regarded as a subset of iron deficiency, that is, it represents the extreme lower end of the distribution of iron deficiency. Treatment options include oral and intravenous iron therapy; however, the efficacy of oral iron i
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YILMAZ, Resul, and Yasemin Asan. "The effect of iron replacement therapy on appetite in children with iron deficiency anemia." Journal of Contemporary Medicine 9, no. 2 (May 1, 2019): 1. http://dx.doi.org/10.16899/jcm.559567.

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Tiwari, Bharti, Amar Singh Tiwari, and Satish Chand Gupta. "A COMPARATIVE RANDOMIZED CLINICAL TRIAL OF NAVAYAS LOUHA SYRUP AND NISHA LOUHA SYRUP IN THE MANAGEMENT OF IRON DEFICIENCY ANEMIA IN INDIAN CHILDREN WITH SPECIAL REFERENCE TO PANDU ROGA." International Journal of Research in Ayurveda and Pharmacy 11, no. 6 (December 30, 2020): 16–21. http://dx.doi.org/10.7897/2277-4343.1106178.

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Iron deficiency is the most usual dietary deficiency worldwide, approximately 25% of the world’s population suffering from iron deficiency anemia according to the World Health Organization. A Neonate has total body iron of 250 mg (80 mg/kg), obtained from maternal sources. In the first 6 months of life, during the period when the infant gets an iron-deficient milk diet, this amount decreases to 60 mg/kg. Infants fed with cow’s milk are at greater risk to develop iron deficiency anemia because calcium from cow’s milk is competing with iron for absorption. There are a large number of formulation
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Markova, E. A., A. Z. Khashukoeva, S. A. Khlynova, M. V. Burdenko, and A. Kh Karanasheva. "Anemia in elderly women. Rational prevention. Evidence base." Meditsinskiy sovet = Medical Council, no. 3 (April 15, 2021): 128–34. http://dx.doi.org/10.21518/2079-701x-2021-3-128-134.

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Iron deficiency anemia is a frequent companion in postmenopausal women and those who have reached adulthood. Anemia in mild form in elderly women often occurs almost asymptomatically. Over time, iron deficiency progresses: severe complications occur, the quality of life decreases significantly, and the prognosis for life becomes unfavorable. A cross-section of the literature data in recent years shows that iron, folate, vitamin B12 deficiency, gastrointestinal diseases, pathologies in the processes of erythropoiesis and other somatic diseases come to the fore in terms of the etiological factor
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Solomon, P. John, Margaret Chellaraj, and A. Priya Margaret. "Anemia in Indian Children and Management." Scholars Journal of Applied Medical Sciences 9, no. 7 (July 17, 2021): 1185–91. http://dx.doi.org/10.36347/sjams.2021.v09i07.012.

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Anemia is defined as hemoglobin level of less than the 5th percentile for age [1]. It is a common condition in children seen in everyday practice. It has to be detected early to prevent complications. Anemia is more common in children below 2 years of age. Most children with mild anemia are asymptomatic. Hence, in many countries where the prevalence of anemia is very high it is common practice to screen for anemia at 1 year of age. Most cases of anemia in our country are caused by nutritional deficiency of iron, and or vitamins. Simple investigations and treatment are adequate to diagnose and
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Gunadi, Dedy, Nelly Rosdiana, and Bidasari Lubis. "Comparison of once a day and three times a day iron treatment in 9 ... 12 year old elementary school children with iron deficiency anemia." Paediatrica Indonesiana 49, no. 2 (April 30, 2009): 104. http://dx.doi.org/10.14238/pi49.2.2009.104-7.

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Background The compliance of iron deficiency anemia treatmentthat is administered three times daily in children is low. Thecompliance will be better if therapy is administered once daily.Objective To compare the iron therapy response of once per dayvs. three times a day administration in 9-12 year old children withiron deficiency anemia.Methods Children with iron deficiency anemia were randomlyallocated into a ferrous sulfate once-daily group or a ferrous sulfatethree times-daily group with the same dose of 5 mg/kg /day ofelemental iron for 30 days. Iron deficiency anemia was definedas Hb <
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Pshenichnaya, Ksenia I., and Tatyana N. Kasatkina. "The efficacy of treatment of early stage of iron-deficiency states in children." Pediatrician (St. Petersburg) 7, no. 4 (December 15, 2016): 128–31. http://dx.doi.org/10.17816/ped74128-131.

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The deficiency of iron is one of the most widespread deficits. This deficiency is most common in the growing organism. There is a large quantity of oral therapies to correct deficit of iron. Usage of any of them can cause adverse side effects. In each and every case the pediatrician should have options to choose most optimal course of treatment of the iron deficiency state, including latent iron deficiency as iron deficiency anemia prophylaxis. The article represents data of using medical food complex “Sideral” in treatment of outpatient children. The drug was used on 44 children in age betwee
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Martín-Masot, Nestares, Diaz-Castro, López-Aliaga, Alférez, Moreno-Fernandez, and Maldonado. "Multifactorial Etiology of Anemia in Celiac Disease and Effect of Gluten-Free Diet: A Comprehensive Review." Nutrients 11, no. 11 (October 23, 2019): 2557. http://dx.doi.org/10.3390/nu11112557.

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Celiac disease (CD) is a multisystemic disorder with different clinical expressions, from malabsorption with diarrhea, anemia, and nutritional compromise to extraintestinal manifestations. Anemia might be the only clinical expression of the disease, and iron deficiency anemia is considered one of the most frequent extraintestinal clinical manifestations of CD. Therefore, CD should be suspected in the presence of anemia without a known etiology. Assessment of tissue anti-transglutaminase and anti-endomysial antibodies are indicated in these cases and, if positive, digestive endoscopy and intest
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Shah, Archana N., Jaini S. Kothari, Dhara P. Desai, Tushar Savaliya, and Rajal B. Prajapati. "Clinical and biochemical outcome in pediatric patients with iron deficiency anemia." International Journal of Contemporary Pediatrics 7, no. 11 (October 21, 2020): 2146. http://dx.doi.org/10.18203/2349-3291.ijcp20204413.

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Background: Iron deficiency is a global public health problem with unique cultural, dietary and infectious hurdles that are difficult to overcome. Aims and objectives were to study clinical and biochemical profile of iron deficiency anemia, risk factors for iron deficiency anemia, presenting illnesses associated with iron deficiency anemia, association of other nutritional deficiency with iron deficiency anemia, treatment of iron deficiency anemia and recovery rate.Methods: This cross-sectional prospective study is conducted between June 2017 to May 2019in a tertiary care institute Gujarat sta
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Moscheo, Carla, Maria Licciardello, Piera Samperi, Milena La Spina, Andrea Di Cataldo, and Giovanna Russo. "New Insights into Iron Deficiency Anemia in Children: A Practical Review." Metabolites 12, no. 4 (March 25, 2022): 289. http://dx.doi.org/10.3390/metabo12040289.

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Iron deficiency anemia (IDA) is the most frequent hematological disorder in children, with an incidence in industrialized countries of 20.1% between 0 and 4 years of age and 5.9% between 5 and 14 years (39 and 48.1% in developing countries). Although IDA has been recognized for a long time, there are still uncovered issues and room for improving the management of this condition. New frontiers regarding its diagnosis and therapeutic options emerge every day; recently, innovative formulations of iron have been launched, both for oral and parenteral administration, with the aim of offering treatm
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Casertano, Marianna, Nicoletta Di Maio, Angela Maria Caprio, Maddalena Casale, Sofia MR Matarese, and Silverio Perrotta. "Quando la carenza di ferro diventa rara…" QUADERNI ACP 28, no. 5 (2021): 254. http://dx.doi.org/10.53141/qacp.2021.254-255.

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Iron deficiency anemia is the most common nutritional disorder in the world, the most widespread form of anemia and the most frequent in children. In the presence of microcytic anemia, evidence of an iron deficiency (transferrin saturation index <10% and ferritin <12 mg/l) allows the diagnosis. An increase in requests and a reduced income are the most common causes in early childhood and adolescence. It is essential to ensure that the disorder is corrected at the end of therapy, in order to exclude rarer causes of iron deficiency. A correct diagnosisi and therapy are also essential to gu
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Hassan, Nabil E. "Reply: Intravenous Ferumoxytol in Pediatric Patients With Iron-Deficiency Anemia." Annals of Pharmacotherapy 51, no. 12 (August 23, 2017): 1146. http://dx.doi.org/10.1177/1060028017726796.

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Iron Deficiency in children is common problem. Its mechanism could be nutritional or due to lack of iron absorption. Several conditions are associated with IDA. Presence of inflammation further complicate attempts to make a definitive diagnoses or accurately quantify reponse to therapy.
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Bhadauria, Arti, Albha Tiwari, Beenu Singh Chauhan, and Poornima Shah. "Correlation between nutritional status parameters and hemoglobin level of teenage girls and hemoglobin level." INTERNATIONAL JOURNAL OF AGRICULTURAL SCIENCES 18, no. 2 (June 15, 2022): 827–31. http://dx.doi.org/10.15740/has/ijas/18.2/827-831.

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Malnutrition is caused by the absence of any essential nutritional factor in the diet, including defects in the formation of hemoglobin or low absorption of essential nutrients. Some malnutrition due to lack of iron in the diet or high quality protein, vitamin B6 deficiency which affects the heme protein in the synthesis of hemoglobin, vitamin E deficiency which affects the stability of the membranes of red blood cells it happens. Copper is not part of the hemoglobin molecule but it affects the absorption of iron in the liver. Iron deficiency is the most common nutritional disorder in the worl
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Chesti, Mohmad Saleem, Shilakha Chaman, and Mudasir Nazir. "Role of iron in breath holding spells and effect of iron therapy in children." International Journal of Contemporary Pediatrics 8, no. 11 (October 25, 2021): 1861. http://dx.doi.org/10.18203/2349-3291.ijcp20214160.

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Background: Breath holding spells (BHS) are paroxysmal events resulting from painful stimulus or emotional event resulting in forceful crying, occur in children’s aged between 6 months to 6 years. To assess the role of iron in breath holding spells (BHS) and to assess the efficiency of iron therapy in reducing frequency of BHS.Methods: This was a prospective, interventional study conducted at GMC baramulla. A total of 70 patients between the ages of 6 months and 5 years with breath holding spells with iron deficiency and iron deficiency anemia were studied. After giving them iron therapy for 6
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MANTADAKIS, ELPIS. "IRON DEFICIENCY ANEMIA IN CHILDREN RESIDING IN HIGH AND LOW-INCOME COUNTRIES: RISK FACTORS, PREVENTION, DIAGNOSIS AND THERAPY." Mediterranean Journal of Hematology and Infectious Diseases 12, no. 1 (June 28, 2020): e2020041. http://dx.doi.org/10.4084/mjhid.2020.041.

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Iron deficiency and iron deficiency anemia (IDA) affect approximately two billion people worldwide and most of them reside in low- and middle-income countries. In these countries, additional causes of anemia include parasitic infections like malaria, other nutritional deficiencies, chronic diseases, hemoglobinopathies and lead poisoning. Maternal anemia in resource-poor nations is associated with low birth weight, increased perinatal mortality and decreased work productivity. Maintaining a normal iron balance in these settings is challenging, as iron-rich foods with good bioavailability are of
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Balashova, E. A., L. I. Mazur, Yu V. Tezikov, and I. S. Lipatov. "The impact of iron deficiency correction in pregnant women on the perinatal period and children’s health status." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 65, no. 1 (March 6, 2020): 51–58. http://dx.doi.org/10.21508/1027-4065-2020-65-1-51-58.

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Purpose. To identify the effects of gestational iron deficiency anemia after treatment with iron-containing drugs during the perinatal period on the health status of full-term children during their 1st year of life.Patients and methods.The authors carried out a prospective observational cohort study of full-term infants of I & II health group from their birth to twelve months. The course of pregnancy and labor was analyzed retrospectively. Hemoglobin, serum ferritin and C-reactive protein were measured in the six and twelve months old children and their mothers in 6 months after giving bir
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Rungngu, Susanti Lisupindan Palimbong, Audrey Wahani, and Max F. J. Mantik. "Reticulocyte hemoglobin equivalent for diagnosing iron deficiency anemia in children." Paediatrica Indonesiana 56, no. 2 (July 19, 2016): 90. http://dx.doi.org/10.14238/pi56.2.2016.90-4.

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Background The prevalence of iron deficiency anemia (IDA) remains high in Indonesian children. When anemia is detected in a patient, the physician’s task is to identify the cause, address it, provide iron therapy, and prevent recurrence. However, prevention is best done by early detection. The reticulocyte hemoglobin equivalent (Ret-He) is a direct measurement of iron level in reticulocytes recently produced in the bone marrow. The Ret-He measurement may be an early indicator of iron deficiency, as it is sensitive at the initial stage of the condition.Objective To assess for a relationship bet
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