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1

Wang, Yufan, Heba Turkstani, Afrah Alfaifi, and Sunday O. Akintoye. "Diagnostic and Therapeutic Approaches to Jaw Osteoradionecrosis." Diagnostics 14, no. 23 (2024): 2676. http://dx.doi.org/10.3390/diagnostics14232676.

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Jaw osteoradionecrosis (ORN) is a major complication of head and neck cancer radiotherapy. Treatment complications account for most of the poor outcomes for head and neck cancers and the associated racial health disparities in cancer survivorship. The global incidence of jaw ORN is improving due to pre-radiotherapy patient preparations and improved head and neck cancer radiotherapy protocols. The diagnosis and management of jaw ORN are based on the patient’s history and clinical presentation combined with radiological and histopathological tests. Evidence-based jaw ORN therapies focus on preve
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Yao, Shengyu, Yin Zhang, Tingfeng Chen, et al. "Dosimetric Comparison Between Jaw Tracking and No Jaw Tracking in Intensity-Modulated Radiation Therapy." Technology in Cancer Research & Treatment 18 (January 1, 2019): 153303381984106. http://dx.doi.org/10.1177/1533033819841061.

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Purpose: This article compares the dosimetric differences between jaw tracking and no jaw tracking technique in static intensity-modulated radiation therapy plans of large and small tumors. Methods: Eight plans with large tumor (nasopharyngeal carcinoma, volume range: 510.9 to 768.0 cm3) and 8 plans with small tumor (single brain metastasis, volume range: 5.3 to 9.9 cm3) treated with jaw tracking on Varian EDGE LINAC were chosen and recalculated with no jaw tracking to study the dosimetric differences. We compared the differences of organ-at-risk doses (Dmax, Dmean), monitor units, and γ passi
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Alderton, Gemma K. "Splitting the jaw." Nature Reviews Cancer 14, no. 7 (2014): 453. http://dx.doi.org/10.1038/nrc3785.

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Patel, V., M. Kelleher, C. Sproat, J. Kwok, and M. McGurk. "New cancer therapies and jaw necrosis." British Dental Journal 219, no. 5 (2015): 203–7. http://dx.doi.org/10.1038/sj.bdj.2015.680.

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Miyamoto, Curtis T., Luther W. Brady, Arnold Markoe, and David Salinger. "Ameloblastoma of the Jaw." American Journal of Clinical Oncology 14, no. 3 (1991): 225–37. http://dx.doi.org/10.1097/00000421-199106000-00009.

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Kim, Haneul, Jaehong Jung, Hyunseo Jung, et al. "Comparison of Jaw Mode and Field Width for Left-Breast Cancer Using TomoDirect Three-Dimensional Conformal Radiation Therapy: A Phantom Study." Healthcare 10, no. 12 (2022): 2431. http://dx.doi.org/10.3390/healthcare10122431.

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It is very important to use effective parameters in the treatment plan of breast cancer patients in TomoDirect (TD)-three-dimensional conformal radiation therapy (TD-3DCRT). The objective of this study was to compare the radiation treatment plans to the parameters (jaw width and jaw mode) of TD-3DCRT for left-breast cancer. This study was conducted using the phantom, the jaw mode (fixed and dynamic) and field width (2.5 cm and 5.0 cm) were controlled to compare the TD-3DCRT treatment plans. There was small difference in the conformity index (CI) and homogeneity index (HI) values for target acc
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7

Nath, Jyotiman, Gautam Sarma, Shachindra Goswami, Shashi Bhushan Sharma, Pranjal Goswami, and Apurba Kumar Kalita. "Split X-Jaw techniques of volumetric modulated arc radiotherapy in nasopharyngeal cancer: A dosimetric comparison." Journal of Cancer Research and Therapeutics 20, no. 3 (2023): 763–69. http://dx.doi.org/10.4103/jcrt.jcrt_1985_22.

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ABSTRACT Purpose: The current study aims to compare the split x-jaw planning technique of volumetric modulated arc radiotherapy (VMAT) with the traditional open and limited jaw techniques of VAMT in nasopharyngeal carcinoma treatment. The multi-leaf collimators on the varian linear accelerator move on a carriage with a maximum leaf span of 15 cm. Therefore, treatment of larger planning target volumes, such as in nasopharyngeal cancer with traditional open and limited jaw technique, yields compromised dose distribution. Method: Computed tomography data sets of 10 nasopharynx cancer patients wer
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8

S, Franjić. "In Shortly about Cancer of the Tongue." Journal of Health Care and Research 1, no. 1 (2020): 7–11. http://dx.doi.org/10.36502/2020/hcr.6152.

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Cancer of the tongue is a type of oral cancer that occurs in the front two-thirds of the tongue. If cancer occurs at the back of the tongue, then it is a type of head or neck cancer. These cancers are extremely rare and occur in a small number of cases. Cancer in the front of the tongue also does not occur as often, but it is the most common type of oral cancer. Cancer of the tongue mainly occurs in squamous cells – thin, flat cells that are found on the surface of all soft tissues, and therefore the tongue. Cancer of the tongue is a disease that affects the front of the tongue, while cancer i
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9

Ebzeev, A. K. "Bisphosphonate-related osteonecrosis of the jaw (BRONJ) in cancer patients." Kazan medical journal 101, no. 2 (2020): 226–31. http://dx.doi.org/10.17816/kmj2020-226.

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This literature review focuses on the latest advances in the study of osteonecrosis of the jaw in cancer patients taking bisphosphonates. Prescribing bisphosphonates for the treatment of metastatic bone disease is justifiable and unavoidable measure. The action of bisphosphonates leads to increase in bone tissue strength, but significantly suppressing normal bone remodelling, essential for repair, and becomes vulnerable to mechanical trauma and bacterial invasion. The unique anatomical and physiological features of the jaw bones determine their selective damage. The disease is characterized by
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10

Karaseva, Vera V., Tatyana M. Elovikova, Sergey E. Zholudev, Anatoly S. Koshcheev, and Artem S. Prihodkin. "Orthopedic rehabilitation of elderly cancer patients as a technology of longevity." BIO Web of Conferences 22 (2020): 01013. http://dx.doi.org/10.1051/bioconf/20202201013.

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Defects after resection of the upper jaw lead to communication of the oral cavity with the nasal cavity, chewing disorders, aesthetic problems and other functional disorders. The aim of the study is to assess the dental status and quality of life of elderly patients with upper jaw defects, as a technology of longevity, at the stage of orthopedic rehabilitation. 24 patients were examined, divided into two groups of 12 people aged from 58 to 74 years. The main group – patients after resection of the upper jaw for malignant neoplasms. Buccal epithelial cells and quality of life of patients were s
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Bhatt, Geetika, Aashish Bhatt, Anthony E. Dragun, Xiao-Feng Li, and A. Cahid Civelek. "Bisphosphonate-Related Osteonecrosis of the Jaw Mimicking Bone Metastasis." Case Reports in Oncological Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/281812.

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Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation, repeat radiological imaging studies revealed osteonecrosis of the jaw. Correlating a patient’s clinica
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12

Spevak, E. M., D. Yu Christophorando, V. A. Shutov, and A. V. Ermakova. "Prevention Of Drug-Induced Osteonecrosis Of The Jaw In Cancer Patients." Creative surgery and oncology 12, no. 2 (2022): 151–58. http://dx.doi.org/10.24060/2076-3093-2022-12-2-151-158.

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The occurrence of drug-induced osteonecrosis of the jaw in cancer patients treated using bone-modifying medications (bisphosphonates and denosumab) is a highly relevant research problem studied by dentists, maxillofacial surgeons, and oncologists. Despite the large number of publications, practical approaches to preventing drug-induced osteonecrosis of the jaw remain to be developed, which is confirmed by the increasing prevalence and severity of the clinical course of the disease. In this article, we review the most significant works and position papers published in Russia and abroad over the
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13

Volos, L. I., and H. L. Stoliar. "BISPHOSPHONATE-INDUCED OSTEONETROCROSIS OF THE JAW IN CANCER PATIENTS: A HISTOPATHOLOGICAL STUDY." Medical Science of Ukraine (MSU) 20, no. 4 (2024): 46–55. https://doi.org/10.32345/2664-4738.4.2024.06.

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Background. Osteonecrosis of the jaw associated with the use of bisphosphonates, such as zoledronic acid, occurs in patients with malignant tumors with metastatic bone lesions and is a severe complication that significantly reduces the quality of life and survival of patients. Aim: to investigate pathomorphological features of bisphosphonate-induced osteonecrosis of the jaw in oncologic patients with metastatic cancer in the bones who used zoledronic acid. Materials and methods. We performed a pathomorphological study of surgical specimens after sequestrectomy of the jaw with bisphosphonate os
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14

Khabibillaevich, Bobonazarov Navruz. "Improvement Of Treatment Of Odontogenic Cysts Of The Jawbone In Children." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 09 (2021): 50–60. http://dx.doi.org/10.37547/tajmspr/volume03issue09-10.

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The improvement of methods of treatment of odontogenic cysts of the jaw remains the actual problem of surgical stomatology. This is caused by the widespread of the disease, the possibility of such complications as cyst abscesses, osteomyelitis development, jaw deformities, tooth loss, pathological fracture occurrence and even the so-called central jaw cancer from the epithelium of cyst walls, and also rather frequent relapses after surgical treatment carried out.
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Ağalar qızı Abbasova, Rumiyə, Sevda Tariyel qızı Hüseynova, Qələndər Xanlar oğlu Əliyev, and Şəhla Rafael qızı Yusubova. "Osteoporosis and the jaw bone." NATURE AND SCIENCE 22, no. 7 (2022): 27–31. http://dx.doi.org/10.36719/2707-1146/22/27-31.

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Osteoporoz aşağı sümük kütləsi və sümük toxumasının mikro arxitekturasının pozulması, nəticədə sümüklərin kövrəkliyi və sınıqlarına həssaslığın artması ilə xarakterizə olunan sistemik skelet xəstəliyidir. Əvvəllər osteoporoz qocalma ilə əlaqəli fizioloji proses hesab edilirdi, lakin bu gün multifaktorial xroniki sistem xəstəlik kimi tanınır. Osteoporozun müalicəsi ilə yanaşı, sümüyə yayılmış xərçəngin müalicəsində bifosfonatlar və denosumab da istifadə olunur. Xərçəngi müalicə etmək üçün bu dərmanların daha yüksək dozalarını qəbul edən insanlar üçün çənənin osteonekroz riski, sadəcə olaraq ost
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16

Susman, Ed. "Jaw Osteonecrosis Seen in Cancer Patients on Bisphosphonates." Oncology Times 27, no. 13 (2005): 28–29. http://dx.doi.org/10.1097/01.cot.0000292601.96718.53.

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Vencio, Eneida F., Charles M. Reeve, K. Krishnan Unni, and Antonio G. Nascimento. "Mesenchymal chondrosarcoma of the jaw bones." Cancer 82, no. 12 (1998): 2350–55. http://dx.doi.org/10.1002/(sici)1097-0142(19980615)82:12<2350::aid-cncr8>3.0.co;2-w.

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Chindia, Mark L. "Osteosarcoma of the jaw bones." Oral Oncology 37, no. 7 (2001): 545–47. http://dx.doi.org/10.1016/s1368-8375(00)00129-9.

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Lončar Brzak, Božana, Lorena Horvat Aleksijević, Ema Vindiš, et al. "Osteonecrosis of the Jaw." Dentistry Journal 11, no. 1 (2023): 23. http://dx.doi.org/10.3390/dj11010023.

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Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs cause drug-induced osteonecrosis. The combination of medications, microbial contamination, and local trauma induces this condition. Osteoradionecrosis is a severe radiation therapy side effect that can affect people with head and neck cancer. It is described as an exposed bone area that does not heal for longer than three months after the end
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20

Donati, Girolamo. "Drug-induced jaw osteonecrosis." Ozone Therapy 4, no. 3 (2019): 48–54. http://dx.doi.org/10.4081/ozone.2019.8698.

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Medication-related osteonecrosis of the jaw (MRONJ), an adverse reaction to medication, has been reported since 2002, at first in cancer patients with bone metastases treated intravenously with pamidronate or zoledronate, and later in patients taking oral bisphosphonate for the treatment of osteoporosis. Several cases of MRONJ have also been described in patients treated with antiangiogenic drugs with a so-called biological target (bevacizumab, sunitinib, sorafenib). Oxygen/ozone therapy for MRONJ treatment represents a possible and efficient alternative to the two main therapeutic approaches
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21

Mansur, Yu P., D. V. Verstakov, and L. N. Scherbakov. "THE ROLE OF ORTHODONTIC CARE IN THE COMPLEX REHABILITATION OF GLOSSECTOMY PATIENTS." BULLETIN of Russian Academy of Natural Sciences 21 (April 2021): 42–45. http://dx.doi.org/10.52531/1682-1696-2021-21-1-42-45.

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n recent years, Russia has seen an increase in the incidence of malignant tumors of the mouth and throat, including tongue cancer. Surgical methods of treatment of cancer of such localization have a crippling character and inevitably lead to disruption of a number of vital functions, including the development of tooth-jaw deformities, which further deteriorates the quality of life of such patients. Timely prescription of orthodontic devices for prophylactic and therapeutic purposes allows to prevent the development of tooth jaw abnormalities and deformities, as well as to treat the already dev
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Dr., Satish Kumar. A. Swapna Moparthi* Nagasri Koka Rupasree Bandla Dr.N.V. Ramarao Prof. Ramarao Nadendla. "A CASE REPORT: ZOLEDRONIC ACID INDUCED JAW OSTEONECROSIS IN PATIENT WITH BONE METASTASIS A RELATIVELY RARE SIDE EFFECT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 09 (2019): 11983–86. https://doi.org/10.5281/zenodo.3457183.

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<strong><em>Introduction:</em></strong><em> Jaw osteonecrosis (JON) is an infrequent side effect observed in patients receiving bisphosphonate therapy for bone maintenance during bone metastasis conditions. Nitrogen based bisphosphonates(NBBP) like Zoledronic acid when given intravenous (IV) infusion have potent ability to develop jaw osteonecrosis as compared to oral therapy. For optimal therapeutic effects and patient compliance perennial&nbsp; administration of Zoledronic acid is preferred.</em> <strong><em>Case Presentation: </em></strong><em>we report a case of 80-year-old woman suffering
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Van Poznak, Catherine. "Osteonecrosis of the jaw and bevacizumab therapy." Breast Cancer Research and Treatment 122, no. 1 (2010): 189–91. http://dx.doi.org/10.1007/s10549-010-0933-9.

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Estilo, Cherry L., Monica Fornier, Azeez Farooki, Diane Carlson, George Bohle, and Joseph M. Huryn. "Osteonecrosis of the Jaw Related to Bevacizumab." Journal of Clinical Oncology 26, no. 24 (2008): 4037–38. http://dx.doi.org/10.1200/jco.2007.15.5424.

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Saito, Kenichi, K. Krishnan Unni, Peter C. Wollan, and Bruce A. Lund. "Chondrosarcoma of the jaw and facial bones." Cancer 76, no. 9 (1995): 1550–58. http://dx.doi.org/10.1002/1097-0142(19951101)76:9<1550::aid-cncr2820760909>3.0.co;2-s.

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Ngoc Thuy Tran, Vy, and Risa Chaisuparat. "Medication‐related osteonecrosis of the jaw: Osteoclast profile in comparison with osteoradionecrosis of the jaw and osteomyelitis of the jaw." Journal of Oral Pathology & Medicine 50, no. 7 (2021): 731–40. http://dx.doi.org/10.1111/jop.13202.

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Venchiarutti, Rebecca L., Masako Dunn, Emma Charters, et al. "Effect of Radiotherapy on Functional and Health-Related Quality of Life Outcomes after Jaw Reconstruction." Cancers 14, no. 19 (2022): 4557. http://dx.doi.org/10.3390/cancers14194557.

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Long-term health-related quality of life (HRQOL) and functional outcomes following mandibular and maxillary reconstruction are lacking. To determine these outcomes, a cross-sectional study of patients with a history of cancer who underwent jaw reconstruction was undertaken. Participants were identified from a database of jaw reconstruction procedures at the Chris O’Brien Lifehouse (Sydney, Australia). Eligible patients had at least one month follow-up, were aged ≥18 years at surgery, and had history of malignancy. HRQOL was measured using the FACE-Q Head and Neck Cancer Module (FACE-Q H&amp;N)
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Wong, Amanda, Daniel Zhu, Jane Y. Tong, Andrew Ko, Tristan Tham, and Dennis Kraus. "The jaw‐dropping costs of oral cavity cancer malpractice." Head & Neck 43, no. 10 (2021): 2869–75. http://dx.doi.org/10.1002/hed.26764.

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Peña-Vega, CP, JP Rodríguez-Mora, and LM Zambrano-Luque. "Metastasis of breast cancer in the jaw: Case report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139, no. 1 (2025): e16-e17. https://doi.org/10.1016/j.oooo.2024.10.197.

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Pu, Jane J., Samer G. Hakim, James C. Melville, and Yu-Xiong Su. "Current Trends in the Reconstruction and Rehabilitation of Jaw following Ablative Surgery." Cancers 14, no. 14 (2022): 3308. http://dx.doi.org/10.3390/cancers14143308.

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The reconstruction and rehabilitation of jaws following ablative surgery have been transformed in recent years by the development of computer-assisted surgery and virtual surgical planning. In this narrative literature review, we aim to discuss the current state-of-the-art jaw reconstruction, and to preview the potential future developments. The application of patient-specific implants and the “jaw-in-a-day technique” have made the fast restoration of jaws’ function and aesthetics possible. The improved efficiency of primary reconstructive surgery allows for the rehabilitation of neurosensory
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Kushadiwijay, Mikhail, Putu Astawa, and I. Gede Eka Wiratnaya. "Systematic Review of Bisphosphonates and Osteonecrosis of the Jaw." International Journal of Research and Review 12, no. 3 (2025): 32–38. https://doi.org/10.52403/ijrr.20250306.

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Introduction: Bisphosphonates commonly prescribed for bone-related conditions but are associated with a side effect called osteonecrosis of the jaw (ONJ). This systematic review investigates ONJ incidence and bisphosphonate types among patients. Methods: Comprehensive systematic search of medical literatures identified five relevant studies. These studies reported 42 ONJ cases in bisphosphonate-treated patients, providing data on affected jaw regions, medication usage, and primary diagnoses. Results: Mandible was the most frequently affected osteonecrosis (40 cases), followed by maxilla (9 cas
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Singh, Annu, Andrew Pischek, Joseph R. Randazzo, et al. "Ramucirumab-related osteonecrosis of the jaw." Oral Oncology 125 (February 2022): 105660. http://dx.doi.org/10.1016/j.oraloncology.2021.105660.

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O'Connor, T. L., A. Padmanabhan, G. Wilding, M. Sullivan, L. Solomon, and D. Lamonica. "Bisphosphonate-induced osteonecrosis of the jaw: Risk factors and diagnostic utility of bone scans." Journal of Clinical Oncology 25, no. 18_suppl (2007): 9052. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9052.

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9052 Background: Osteonecrosis of the jaw (ONJ) is a serious long-term effect of intravenous bisphosphonates. We report characteristics of patients with ONJ at Roswell Park Cancer Institute (RPCI) and utility of bone scans in its diagnosis. Methods: Patients were identified using RPCI database. ONJ diagnosed was staged using the system used for jaw osteoradionecrosis (Schwartz et al, Am J Clin Oncol, 2002). Controls included patients receiving bisphosphonates between July 2002 and 2006. Routine whole body bone scans were reviewed for jaw uptake. Statistical analysis was done using SAS 9.1. Res
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Darling, Harry S. "Medication Related Osteonecrosis of Jaw: A Medical Oncologist’s Perspective." Journal of Dental and Maxillofacial Surgery 1, no. 1 (2018): 10–17. http://dx.doi.org/10.18314/jdms.v1i1.1180.

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Medication related osteonecrosis of jaw (MRONJ) is a rare iatrogenic disease. Cancer therapeutics is advancing exponentially and apart from a major emphasis on quality of life (QoL) in metastatic patients, now we are foreseeing increased longevity. This necessitates the rising need of betterment of supportive care modalities and looking into the rare complications of therapy. Bisphosphonates (BPs) and Denosumab, the anti-resorptive agents (ARAs) used commonly by medical oncologists in cancers with bone metastases and less commonly in prevention or treatment of osteoporosis, are implicated in t
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Elizabeth, Caroline Palaparthi, Nethagani Jayalatha, Govula Priyanka, Siddhardha Chandaka, Manthri Randheer, and Devu Sridhar. "Metastatic Intraosseous Adenoid Cystic Carcinoma of Mandible - A Rare Central Salivary Gland Neoplasm." International Journal of Medical Science and Clinical Research Studies 02, no. 02 (2022): 125–31. https://doi.org/10.5281/zenodo.6221818.

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A 40 year old male subject came to MNJ Institute of Oncology and Regional Cancer Centre, Hyderabad with complaints of left lower molar tooth ache for 7 months and swelling of jaw, which gradually increased in size over 2 months. The patient is unable to open his mouth completely with restriction of jaw movements.History of weight loss. He is a chronic smoker for 20 years and takes alcohol occasionally.
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Chee, Shuzhen, Yasmeen M. Byrnes, Kevin T. Chorath, Karthik Rajasekaran, and Jie Deng. "Interventions for Trismus in Head and Neck Cancer Patients: A Systematic Review of Randomized Controlled Trials." Integrative Cancer Therapies 20 (January 2021): 153473542110064. http://dx.doi.org/10.1177/15347354211006474.

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Background: Current treatment for head and neck cancers (HNCs) have led to an improved survival. However, the sequelae of cancer treatment often result in trismus, or reduced mouth opening. The purpose of this report is to identify interventional studies for trismus management in HNC patients. Methods: A search of PubMed, Embase, Cumulated Index to Nursing and Allied Health Literature, and the Cochrane Library was conducted in March 2020 for randomized controlled trials (RCTs) involving interventions for trismus for head and neck cancer within 10 years. Intervention could involve the use of an
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Kutukova, Svetlana, Natalya Belyak, Grigoriy Raskin, et al. "THE PROGNOSTIC VALUE OF PD-L1 EXPRESSION IN TUMOR AND IMMUNE CELLS IN SQUAMOUS CELL CARCINOMA OF THE ORAL MUCOSA." Problems in oncology 63, no. 5 (2017): 759–65. http://dx.doi.org/10.37469/0507-3758-2017-63-5-759-765.

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The most frequent of malignant tumor cites of the oral mucosa are tongue - 55 %, mucosa of the cheek - 12 %, the fundus of the oral cavity - 10 %, the alveolar process of the upper jaw and the hard palate - 9 %, the alveolar process of the lower jaw - 6 %, the soft palate - 2 %. Malignant tumor cells carry PD-L1 ligands on their surface and its expression level is often correlated with an unfavorable prognosis in particular for such tumors as melanoma, kidney cancer and non-small cell lung cancer. It is relevant to evaluate the correlation between overexpression of PD-L1 and overall survival i
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Kotova, I. V., M. E. Beloshitsky, and V. G. Ignatuk. "BONE CHANGES IN JAWS AS A RESULT OF PRIMARY HYPERPARATHYROIDISM." Tavricheskiy Mediko-Biologicheskiy Vestnik 23, no. 2 (2020): 80–84. http://dx.doi.org/10.37279/2070-8092-2020-23-2-80-84.

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An analysis of bone changes in the jaws caused by primary hyperparathyroidism (PHPT) was performed based on the research and our own studies. Presented are the modern principles for the diagnosis of PHPT in patients undergoing treatment in maxillofacial clinics with recurrent epulids and jaw cysts. Variously expressed tumor jaw lesions were observed in 23 of 751 patients. 19 of them have the lower jaw, and 4 have the upper jaw tumors. Tumorous masses in 15 patients were caused by parathyroid adenoma, in 7 – by hyperplasia, in 1 – by cancer. The only clinical manifestation of hyperparathyroidis
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Kotova, I. V., M. E. Beloshitsky, and V. G. Ignatuk. "BONE CHANGES IN JAWS AS A RESULT OF PRIMARY HYPERPARATHYROIDISM." Tavricheskiy Mediko-Biologicheskiy Vestnik 23, no. 2 (2020): 80–84. http://dx.doi.org/10.37279/2070-8092-2020-23-2-80-84.

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An analysis of bone changes in the jaws caused by primary hyperparathyroidism (PHPT) was performed based on the research and our own studies. Presented are the modern principles for the diagnosis of PHPT in patients undergoing treatment in maxillofacial clinics with recurrent epulids and jaw cysts. Variously expressed tumor jaw lesions were observed in 23 of 751 patients. 19 of them have the lower jaw, and 4 have the upper jaw tumors. Tumorous masses in 15 patients were caused by parathyroid adenoma, in 7 – by hyperplasia, in 1 – by cancer. The only clinical manifestation of hyperparathyroidis
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Shankar, Naveen, Preethi Sunkara, and Utpal Nath. "A double-negative feedback loop between miR319c and JAW-TCPs establishes growth pattern in incipient leaf primordia in Arabidopsis thaliana." PLOS Genetics 19, no. 9 (2023): e1010978. http://dx.doi.org/10.1371/journal.pgen.1010978.

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The microRNA miR319 and its target JAW-TCP transcription factors regulate the proliferation-to-differentiation transition of leaf pavement cells in diverse plant species. In young Arabidopsis leaf primordia, JAW-TCPs are detected towards the distal region whereas the major mRNA319-encoding gene MIR319C, is expressed at the base. Little is known about how this complementary expression pattern of MIR319C and JAW-TCPs is generated. Here, we show that MIR319C is initially expressed uniformly throughout the incipient primordia and is later abruptly down-regulated at the distal region, with concomit
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O'Connor, T. L., N. Ngamphaiboon, M. Sullivan, E. B. Kossoff, A. Elefante, and J. L. Frustino. "Dental outcomes of osteonecrosis of the jaw (ONJ)." Journal of Clinical Oncology 29, no. 15_suppl (2011): e19675-e19675. http://dx.doi.org/10.1200/jco.2011.29.15_suppl.e19675.

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Antonuzzo, Lorenzo, Alice Lunghi, Elisa Giommoni, Marco Brugia, and Francesco Di Costanzo. "Regorafenib Also Can Cause Osteonecrosis of the Jaw." Journal of the National Cancer Institute 108, no. 4 (2016): djw002. http://dx.doi.org/10.1093/jnci/djw002.

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S. Medneva, Teodora, and Rosen B. Tsolov. "Stress assessment in patients with medication-related osteonecrosis of the jaw." International Journal of Management Studies and Social Science Research 06, no. 06 (2024): 79–88. https://doi.org/10.56293/ijmsssr.2024.5311.

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Objectives: Medication-related osteonecrosis of the jaw (MRONJ) has become increasingly common due to the widespread use of antiresorptive drugs in cancer and osteoporosis treatment. Cancer diagnosis and treatment, particularly with concurrent serious illnesses, impose significant stress on patients. There is welldocumented evidence linking cancer progression with stress, suggesting that psychosocial factors may influence disease development. This study aimed to evaluate stress levels in MRONJ patients, defining their physical, psychological, and behavioral responses, and exploring correlation
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Pustovaya, I. V., M. A. Engibaryan, P. V. Svetitskiy, et al. "Orthopedic treatment in cancer patients with maxillofacial pathology." South Russian Journal of Cancer 2, no. 2 (2021): 22–33. http://dx.doi.org/10.37748/2686-9039-2021-2-2-3.

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Relevance. Staged orthopedic treatment was used to improve the quality of life of patients who underwent radical maxillofacial surgeries for cancer.Patients and methods. 197 patients receiving treatment for maxillofacial cancer were observed at the Department of head and neck tumors, National Medical Research Centre for Oncology of the Ministry of Health of Russia, in 1998- 2018. All patients underwent radical surgical treatment resulting in postoperative defects of the upper jaw, soft tissues of the zygomatic- buccal-orbital region, nose, or auricle.Results. Removable obturator prostheses wit
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Kut, Victoria, J. Mehta, S. Singhal, and C. Bennett. "Post-Marketing Assessments of Serious Adverse Drug Reactions Reported by the Manufacturer to the FDA Differ Markedly with Those from an Independent Pharmacovigilance Program: Empirical Findings Based on Bisphosphonate-Associated Osteonecrosis Descriptions by the Research on Adverse Events and Reports Project and the Product Manufacturer." Blood 104, no. 11 (2004): 3151. http://dx.doi.org/10.1182/blood.v104.11.3151.3151.

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Abstract Background: The Research on Adverse Events and Reports (RADAR) project, an independent pharmacovigilance project, has reported that post-marketing dissemination of clinical information on systemic adverse drug reactions (sADRs) in the FDA approved package labels of cancer drugs is often incomplete, delayed, or absent. Methods: We compared post-marketing clinical assessments describing one previously unreported sADR: zoledronate (Z) and pamidronate (P)-associated osteonecrosis (ON) of the jaw. Data sources included 1) information submitted to the FDA by the manufacturer in support of a
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Woo, S. B., and D. H. Solomon. "Bisphosphonate Therapy for Cancer and Prevalence of Inflammatory Jaw Conditions." JNCI Journal of the National Cancer Institute 99, no. 13 (2007): 986–87. http://dx.doi.org/10.1093/jnci/djm029.

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Sanna, G., L. Preda, R. Bruschini, et al. "Bisphosphonates and jaw osteonecrosis in patients with advanced breast cancer." Annals of Oncology 17, no. 10 (2006): 1512–16. http://dx.doi.org/10.1093/annonc/mdl163.

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Hedin, Emma, Anna Bäck, and Roumiana Chakarova. "Jaw position uncertainty and adjacent fields in breast cancer radiotherapy." Journal of Applied Clinical Medical Physics 16, no. 6 (2015): 240–51. http://dx.doi.org/10.1120/jacmp.v16i6.5673.

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Mehmood, Faisal, Hajra Jamil, Jose Machain, Joseph Fares, and Gavin Levinthal. "S2922 Jaw Pain - A Rare Presentation of Metastatic Colon Cancer." American Journal of Gastroenterology 119, no. 10S (2024): S2005. http://dx.doi.org/10.14309/01.ajg.0001041056.71190.3e.

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Wu, J., L. Min, K. Shengwei, et al. "Lung SBRT Using Helical Tomotherapy: Dosimetric and Delivery Comparison of Dynamic Jaw and Fixed Jaw." International Journal of Radiation Oncology*Biology*Physics 108, no. 3 (2020): e258. http://dx.doi.org/10.1016/j.ijrobp.2020.07.621.

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