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1

Negishi, Masayoshi. "HIV/AIDS Care at Tokyo Metropolitan Komagome Hospital." Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 14 (1997): S35—S37. http://dx.doi.org/10.1097/00042560-199700002-00007.

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Masuda, G., A. Ajisawa, M. Negishi, et al. "Entamoeba histolytica/dispar infections in HIV-positive individuals presented at Tokyo Metropolitan Komagome Hospital, Tokyo." Parasitology International 47 (August 1998): 199. http://dx.doi.org/10.1016/s1383-5769(98)80518-7.

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YASUNO, Akira, Seizo UCHIDA, Hiroshi YAMAGUCHI, Yuichi INOUE, Etsuko YANAGIHA, and Mihoko KUBOTA. "THE CONSTRUCTION PROCESS AND DESIGN OF A REINFORCED CONCRETE APARTMENT BUILDING IN KOMAGOME, TOKYO (1938)." Journal of Architecture and Planning (Transactions of AIJ) 71, no. 600 (2006): 203–9. http://dx.doi.org/10.3130/aija.71.203_2.

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Ebara, T., K. Karasawa, K. Maebayashi, et al. "Radiation therapy for Kaposi's sarcoma associated with acquired immunodeficiency syndrome: Tokyo Metropolitan Komagome Hospital experience." International Journal of Clinical Oncology 5, no. 6 (2000): 395–98. http://dx.doi.org/10.1007/pl00012069.

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Suzuki, C., G. Masuda, S. Kano, and M. Suzuki. "Clinical and in vitro efficacy of anti-malarial drugs on 16 Plasmodium falciparum malaria experienced at Tokyo metropolitan Komagome hospital, Tokyo, Japan." Parasitology International 47 (August 1998): 237. http://dx.doi.org/10.1016/s1383-5769(98)80643-0.

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Hoshino, Yoshihiko, Gohta Masuda, Masayoshi Negishi, et al. "Clinical and Bacteriological Profiles of Patients with Typhoid Fever Treated during 1975-1998 in the Tokyo Metropolitan Komagome Hospital." Microbiology and Immunology 44, no. 7 (2000): 577–83. http://dx.doi.org/10.1111/j.1348-0421.2000.tb02536.x.

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Fujita, Yoshihiko, Noriko Matsunaga, Maiko De Kerckhove, Shoichi Tomita, Miwako Fujii, and Yasunobu Terao. "Animation of latissimus dorsi flap in breast reconstruction: a retrospective analysis based on 203 cases." Journal of Plastic Surgery and Hand Surgery 59 (October 15, 2024): 128–31. http://dx.doi.org/10.2340/jphs.v59.39952.

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Background: Breast animation is a common postoperative complication of breast reconstruction surgery. This study investigates the factors affecting the onset and degree of animation to suggest an ideal treatment strategy for this complication. Methods: This study included patients who underwent latissimus dorsi reconstruction at Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, between 2009 and 2020 and had an outpatient visit after July 2020. Statistical analysis was performed and the patients’ background and surgical factors were examined to determine whether they
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Nakajima, Yasushi, Akane Yoshida, and Tsuyoshi Kato. "Report on the Project on the Implementation of Continuity Operations in Disaster-Affected Healthcare Facilities Using Gensai Calendar HDMG and COOP Flow Diagram." Journal of Disaster Research 18, no. 2 (2023): 114–23. http://dx.doi.org/10.20965/jdr.2023.p0114.

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Based on the lessons learned from past disasters, the Japanese Ministry of Health, Labour and Welfare has notified the establishment of disaster base hospitals and ensured medical care continuity based on business continuity plan (BCP). Following these, we created a disaster management training program with 45 items, the Disaster Mitigation (Gensai) Calendar for Healthcare Disaster Management Guide (HDMG)* (“Gensai Calendar”) in 2018. Thereafter, a three-year multicenter project was launched at the Tokyo Metropolitan Hospital Organization to introduce the “Gensai Calendar” and assess its merit
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9

KAMINUMA, Takuya, Katsuyuki KARASAWA, Nahoko HANYU, et al. "Acute Adverse Effects of Radiation Therapy on HIV-positive Patients in Japan: Study of 31 Cases at Tokyo Metropolitan Komagome Hospital." Journal of Radiation Research 51, no. 6 (2010): 749–53. http://dx.doi.org/10.1269/jrr.10090.

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Kobayashi, Takeshi, Takuya Yamashita, Miwa Sakai, et al. "Single-Institute Analysis of Allogeneic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia." Blood 106, no. 11 (2005): 5445. http://dx.doi.org/10.1182/blood.v106.11.5445.5445.

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Abstract Purpose We report the outcomes of allogeneic stem cell transplantation (SCT) for the patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) in a single center. Patients and Methods Between August 1993 and March 2005, 36 patients with Ph+ALL received SCT at Tokyo Metropolitan Komagome Hospital. The median age was 41 years (range; 17 to 60 years). All patients received myeloablative conditioning regimen (cytosine arabinoside, cyclophosphamide and fractionated 12Gy total-body irradiation). Stem cell source of SCT was 14 related donors (bone marrow [n=9] and
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11

Takagi, Maki, Misato Takao, Nozomi Funatsu, et al. "Clinicopathologic characteristics of patients with early-onset colorectal cancer." Journal of Clinical Oncology 42, no. 3_suppl (2024): 74. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.74.

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74 Background: Although the incidence of colorectal cancer has been declining in the United States in recent years, the incidence of young patients under 50 years of age has been reported to be increasing by several percent per year. Various studies have been conducted to characterize early-onset colorectal cancer (EO-CRC); however, it has been unclear whether it is a different entity from late-onset colorectal cancer (LO-CRC). In this study, we evaluated the clinicopathologic characteristics of EO-CRC in Japan. Methods: This study included 1,336 patients who underwent surgical resection for c
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12

Saji, S., N. Ishizuka, K. Horiguchi, et al. "Age frequency distribution of joint ER/PR phenotypes in primary breast cancer patients: An analysis of 3,620 cases at a single Japanese institute." Journal of Clinical Oncology 24, no. 18_suppl (2006): 597. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.597.

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597 Background: Hormone receptor (HR) expression may reflect the different subtypes of breast cancer. Recent clinical trials have reported that joint Estrogen receptor (ER)/Progesterone receptor (PR) phenotypes in breast cancer have specific spectrum for treatment response. To analyze the epidemiologic character of ER/PR subtypes in Japanese patients, a retrospective data survey was conducted for 3,620 breast cancer patients treated at a single institute during 1975–2005. Methods: Patients records were obtained from cancer registration of the Tokyo Metropolitan Cancer and Infectious Diseases C
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13

Akiyama, Hideki, Wataru Munakata, Takeshi Kobayashi, et al. "Morbidity and Mortality Later Than 2 Years After HSCT. A Sinle Institution Experience." Blood 116, no. 21 (2010): 4508. http://dx.doi.org/10.1182/blood.v116.21.4508.4508.

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Abstract Abstract 4508 Long-term follow-up data of the patients who underwent HSCT more than 2 years ago at a single institution in Japan was presented. The patients who received first allogeneic hematopoietic stem cell transplantation (HSCT) at Tokyo Metropolitan Komagome Hospital between January, 1990 and December, 2007 under hematology division were included. Follow-up data were obtained annually from the medical records if the patients visited our institution regularly. If the patients were not followed in our institution, follow-up data were requested to the hospitals where the patients h
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14

Tokisawa, Hiromi, Tomoyuki Aruga, Yayoi Honda, et al. "Abstract P4-07-25: Distant metastasis of breast cancer is triggered by changes in the dynamics of metastatic cells after removal of the primary lesion." Cancer Research 82, no. 4_Supplement (2022): P4–07–25—P4–07–25. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-07-25.

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Abstract PURPOSE Breast cancer subtype influences the dynamics of distant recurrence. We investigated the timing of distant recurrence (distant disease-free interval DDFI) for each subtype and its relationship to stage, and perioperative treatment. PATIENTS AND METHODS We retrospectively analyzed data from 4,658 patients with stage I-III invasive breast cancer operated at Tokyo Metropolitan Komagome Hospital from 1998 to 2018. Patients were classified into five biological subtypes according to estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor 2 (HER2), and nucl
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15

Toya, Takashi, Ayumi Taguchi, Kazutaka Kitaura, et al. "Clonal Dynamics and Publicness of CMV-Specific TCR Repertoire after Allogeneic Stem Cell Transplantation." Blood 134, Supplement_1 (2019): 4551. http://dx.doi.org/10.1182/blood-2019-122894.

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[Background] Cytomegalovirus (CMV) disease is a major complication after allogeneic stem cell transplantation (SCT). However, mechanisms of adoptive immunity against CMV are not fully elucidated. Recently, high-throughput next-generation sequencing (NGS) technology made it possible to shed light on the detailed and comprehensive landscape of T-cell receptor (TCR) repertoire. In this study, we analyzed TCR repertoire of CMV-specific cytotoxic T-cells (CMV-CTLs) in patients who suffered from CMV reactivation after SCT to clarify the diversity and dynamics of CMV-specific T-cell immunity. [Method
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16

Ishiba, Toshiyuki, Mio Adachi, Sakiko Maruya, et al. "Abstract P4-07-09: Does energy device improve operative procedure and postoperative management of total mastectomy with axillary lymph node dissection?" Clinical Cancer Research 31, no. 12_Supplement (2025): P4–07–09—P4–07–09. https://doi.org/10.1158/1557-3265.sabcs24-p4-07-09.

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Abstract Background: Axillary lymph node dissection (ALND) is still necessary in breast surgery, although it is now less frequently employed. Although it is often experienced that increased surgeon experience and better performance of the surgical equipment used reduces operative time and blood loss, there are still few reports on the extent to which these improvements are reflected in the recent introduction of recent ENERGY devices. Furthermore, the vessel sealing effect of energy devices is expected to reduce the volume of discharge after ALND, which is expected to improve postoperative man
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17

Kishida, Yuya, Yuho Najima, Yuki Otsuka, et al. "Post-Transplant Maintenance Treatment with Ponatinib for Philadelphia Chromosome Positive Leukemia." Blood 134, Supplement_1 (2019): 5694. http://dx.doi.org/10.1182/blood-2019-128031.

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[Background] Philadelphia chromosome positive (Ph+) leukemia is characterized by highly proliferative nature and clone instability that evokes the emergence of mutated clones, including BCR-ABL1 T315I mutated clone. Established evidence on the use of tyrosine kinase inhibitors (TKIs) after allogeneic hematopoietic stem cell transplantation (HSCT) is still lacking. The use of second-generation TKIs as a maintenance treatment after HSCT has been studied, and it is expected that their use would improve the prognosis by suppressing recurrence. The advent of ponatinib (PON), a potent inhibitor of t
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18

Hara, Kentaro, Haruhiko Cho, Atsushi Onodera, et al. "Long‐term treatment outcomes in gastric cancer with oligometastasis." Annals of Gastroenterological Surgery, August 31, 2023. http://dx.doi.org/10.1002/ags3.12733.

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AbstractAimWhile surgery is essential for curative treatment of gastric cancer with oligometastasis, its target, timing, and possibility of combination with other treatments are unclear. We herein investigated the clinical course and long‐term outcomes of gastric cancer with oligometastasis in the real world setting to determine the optimal therapeutic strategy.MethodsThe present study retrospectively analyzed 992 patients who received any treatment for metastatic or recurrent gastric adenocarcinoma at Tokyo Metropolitan Komagome Hospital between 2007 and 2019. Oligometastasis was defined as a
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19

Kimura, Masamichi, Koji Nishikawa, Jun Imamura, and Kiminori Kimura. "Frontline evaluation: Atezolizumab–bevacizumab versus lenvatinib for BCLC stage B hepatocellular carcinoma exceeding the up‐to‐seven criteria." Cancer Medicine 13, no. 18 (2024). http://dx.doi.org/10.1002/cam4.70217.

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AbstractIntroductionThis study aimed to evaluate the efficacy and safety of atezolizumab combined with bevacizumab (Atez/Bev) compared to lenvatinib (LEN) as first‐line systemic therapy for patients with Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma (HCC) exceeding the up‐to‐seven criteria threshold, who are typically unsuitable for transarterial chemoembolization (TACE).MethodsA retrospective analysis was conducted on 49 consecutive patients with HCC treated at Tokyo Metropolitan Komagome Hospital between May 2018 and October 2023. The patients were divided into two gr
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20

Zhang, Xian-Da, Yao Zhang, Yi-Zhou Zhao, Chun-Hua Zhou, and Duo-Wu Zou. "Autoimmune pancreatitis: A bibliometric analysis from 2002 to 2022." Frontiers in Immunology 14 (February 22, 2023). http://dx.doi.org/10.3389/fimmu.2023.1135096.

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Background/ObjectivesAutoimmune pancreatitis (AIP) is a distinct form of pancreatic inflammatory disease that responds well to glucocorticoid therapy. Knowledge on AIP has rapidly evolved over the past two decades. Based on bibliometric analysis, this study aimed to assess the research status of AIP over the past two decades and determine the research focus and emerging topics.MethodsAIP-related publications published between January 1, 2002, and June 6, 2022, were retrieved from the Web of Science Core Collection. Bibliometric data were analyzed using HisCite, VOSviewer, CiteSpace, and biblio
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"Simple fluorescent EIA for detection and quantification of hepatitis C viremia 1) Tokyo Metro. Komagome Hosp. Japan. 2) Univ Florida College of Medicine, USA. 3) Nagoya City Univ., Japan. 4) Shinshu Univ. Japan. 5) Tokyo Metro Inst Medi Sci Japan. 6) Intern Reagents Co., Japan. 7) Tonen Co., Japan." Hepatology 22, no. 4 (1995): A355. http://dx.doi.org/10.1016/0270-9139(95)95144-x.

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"Significance of serum hepatitis C virus core protein level in patients with chronic hepatitis C , 1Department of Medicine, Nagoya City University of Medical School, Nagoya, Japan, 2Section of Hepatobiliary Diseases, University of Florida, USA. 3Liver Unit, The Metropolitan Komagome Hospital, Japan, 4Department of Microbiology, The Tokyo Metropolitan Institute of Medical Science, Japan." Hepatology 22, no. 4 (1995): A469. http://dx.doi.org/10.1016/0270-9139(95)95599-2.

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