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Artykuły w czasopismach na temat "Langerhans islet"
Miralles, Francisco, Tadej Battelino, Paul Czernichow i Raphael Scharfmann. "TGF-β Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the Matrix Metalloproteinase MMP-2". Journal of Cell Biology 143, nr 3 (2.11.1998): 827–36. http://dx.doi.org/10.1083/jcb.143.3.827.
Pełny tekst źródłaDa Silva Xavier, Gabriela. "The Cells of the Islets of Langerhans". Journal of Clinical Medicine 7, nr 3 (12.03.2018): 54. http://dx.doi.org/10.3390/jcm7030054.
Pełny tekst źródłaBucher, Mathe, Bosco, Andres, Bühler, Morel i Berney. "Islet of Langerhans Transplantation for the Treatment of Type 1 Diabetes". Swiss Surgery 9, nr 5 (1.10.2003): 242–46. http://dx.doi.org/10.1024/1023-9332.9.5.242.
Pełny tekst źródłaGoess, Ruediger, Ayse Mutgan, Umut Çalışan, Yusuf Erdoğan, Lei Ren, Carsten Jäger, Okan Safak i in. "Patterns and Relevance of Langerhans Islet Invasion in Pancreatic Cancer". Cancers 13, nr 2 (11.01.2021): 249. http://dx.doi.org/10.3390/cancers13020249.
Pełny tekst źródłaGoess, Ruediger, Ayse Ceren Mutgan, Umut Çalışan, Yusuf Ceyhun Erdoğan, Lei Ren, Carsten Jäger, Okan Safak i in. "Patterns and Relevance of Langerhans Islet Invasion in Pancreatic Cancer". Cancers 13, nr 2 (11.01.2021): 249. http://dx.doi.org/10.3390/cancers13020249.
Pełny tekst źródłaCrowther, N. J., C. F. Gotfredsen, A. J. Moody i I. C. Green. "Immunological and insulin secretory studies on isolated porcine islets of Langerhans". Journal of Endocrinology 126, nr 1 (lipiec 1990): 43–49. http://dx.doi.org/10.1677/joe.0.1260043.
Pełny tekst źródłaVan Der Burg, Michael P. M., Onno R. Guicherit, Marijke Frölich, Frans A. Prins, Jan Anthonie Bruijn i Hein G. Gooszen. "Cell Preservation in University of Wisconsin Solution during Isolation of Canine Islets of Langerhans". Cell Transplantation 3, nr 4 (lipiec 1994): 315–24. http://dx.doi.org/10.1177/096368979400300408.
Pełny tekst źródłaSamejima, Tadashi, Kenji Yamaguchi, Hiroo Iwata, Noriyuki Morikawa i Yoshito Ikada. "Gelatin Density Gradient for Isolation of Islets of Langerhans". Cell Transplantation 7, nr 1 (styczeń 1998): 37–45. http://dx.doi.org/10.1177/096368979800700106.
Pełny tekst źródłaWestermark, Gunilla T., i Per Westermark. "Transthyretin and Amyloid in the Islets of Langerhans in Type-2 Diabetes". Experimental Diabetes Research 2008 (2008): 1–7. http://dx.doi.org/10.1155/2008/429274.
Pełny tekst źródłaHurst, R. D., S. L. F. Chan i N. G. Morgan. "Effects of benextramine on the adrenergic inhibition of insulin secretion in isolated rat pancreatic islets". Journal of Molecular Endocrinology 2, nr 2 (marzec 1989): 99–105. http://dx.doi.org/10.1677/jme.0.0020099.
Pełny tekst źródłaRozprawy doktorskie na temat "Langerhans islet"
Ar'Rajab, Aamer. "Islet transplantation in the treatment of diabetes number of islets, functional regulation and metabolic control /". Lund : Dept. of Surgery, Lund University, 1991. http://catalog.hathitrust.org/api/volumes/oclc/38187937.html.
Pełny tekst źródłaNyqvist, Daniel. "In vivo imaging of islet cells and islet revascularization /". Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-116-6/.
Pełny tekst źródłaAlves, Figueiredo Hugo Jorge. "Improving islet-graft revascularization". Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/586309.
Pełny tekst źródłaIslet transplantation is considered a potentially curative treatment for type 1 diabetes, Despite the key important advances achieved by the establishment of the Edmonton protocol, islet transplantation remains clinically limited due to several challenges, which lead to massive islet loss or failure of the grafts. Therefore searching for new targets to facilitate islet revascularization may lead to improved future results in cell transplantation.Islets native architecture is characterized by a dense vessel network that, delivers oxygen, hormones, glucose, and nutrients to islet’s cells allowing them to function correctly. After transplantation, the survival and function of islet grafts must depend on the reestablishment of new vessels within the grafts to derive blood flow from the host vascular system. This vascular network is severed when islets are isolated for transplantation, and even though islets freely revascularize, they do not reach the levels of vascularization present in endogenous pancreatic islets, which results in the impairment of grafts function and survival. Altogether, the lack of a proper vascular network account as the primary responsible for early graft loss. Although the molecular mechanisms underlying islet revascularization remain elusive, a number of factors have been implicated, such as the vascular endothelial growth factor A (VEGFA), a key angiogenic molecule that acts to stimulate new vessel formation. VEGFA expression in transplanted islets is significantly impaired, which is further pronounced in prevailing hyperglycemia, and coincides with delayed and insufficient islet revascularization in diabetic mice In this thesis we identify for the first time, tyrosine phosphatase PTP-1B as a target for improving graft revascularization. We targeted PTP-1B, either by its inhibition, following a sodium tungstate treatment after transplantation, or by transplanting islets lacking PTP-1B, using a genetic model of PTP-1B knock-out, or following genetic silencing, using siRNA and shRNA Lentivirus particles. Following transplantation into the anterior chamber of the eye in diabetic mice, islet-grafts showed increased revascularization by inducing the expression of VEGF-A by ß-cells in the graft. This improved revascularization was followed by an improvement of islet-graft survival and function, as transplanted mice recovered normoglycemia and glucose tolerance. Furthermore, we demonstrated that PTP-1B induces VEGF-A expression and secretion in islets by upregulating HIF1A-independent PGC1α/ERRα signaling. Finally, we demonstrated that this regulatory mechanism is conserved in human islets. Together, these findings unravel the potential role of PTP-1B as a target for improving islet transplantation outcomes.
Blais, Debbie Lin Marie. "Becoming an islet cell allotransplant recipient". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq21258.pdf.
Pełny tekst źródłaJohansson, Ulrika. "Formation of Composite Islet Grafts A novel strategy to promote islet survival and revascularization /". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-102788.
Pełny tekst źródłaCoffey, Lane Claire Katherine. "Immune Cells, Inflammatory Molecules, and CD40 in Nonhuman Primate Islets of Langerhans". Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/430.
Pełny tekst źródłaCabric, Sanja. "Pancreatic Islet Transplantation : Modifications of Islet Properties to Improve Graft Survival". Doctoral thesis, Uppsala University, Department of Oncology, Radiology and Clinical Immunology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8333.
Pełny tekst źródłaDuring the past decade clinical islet transplantation has become a viable strategy for curing type 1 diabetes. The limited supply of organs, together with the requirement for islets from multiple donors to achieve insulin independence, has greatly limited the application of this approach.
The islets are infused into the liver via the portal vein, and once exposed to the blood, the grafted tissue has been shown to be damaged by the instant blood-mediated inflammatory reaction (IBMIR), which is characterized by coagulation and complement activation as well as leukocyte infiltration into the islets. Islet revascularization is a subsequent critical step for the long-term function of the transplanted graft, which may partially be impeded by the IBMIR.
In this thesis, we have explored novel strategies for circumventing the effects of the IBMIR and facilitating islet revascularization.
Systemic inhibitors of the IBMIR are typically associated with an increased risk of bleeding. We therefore evaluated alternative strategies for modulating the islets prior to transplantation. We demonstrated, using an adenoviral vector, that a high level of expression and secretion of the anticoagulant hirudin could be induced in human islets. An alternative approach to limiting the IBMIR was developed in which anticoagulant macromolecular heparin complexes were conjugated to the islet surface. This technique proved effective in limiting the IBMIR in both an in vitro blood loop model and an allogeneic porcine model of islet transplantation. An increased adhesion of endothelial cells to the heparin-coated islet surface was demonstrated, as was the capacity of the heparin conjugate to bind the angiogenic factors VEGF and FGF; these results have important implications for the revascularization process.
The outcome of the work in this thesis suggests that modulation of the islet surface is an attractive alternative to systemic therapy as a strategy for preventing the IBMIR. Moreover, the same techniques can be employed to induce revascularization and improve the engraftment of the transplanted islets. Ultimately, improved islet viability and engraftment will make islet transplantation a more effective procedure and increase the number of patients whose diabetes can be cured.
Ma, Zhi. "Islet amyloid polypeptide (IAPP) : mechanisms of amyloidogenesis in the pancreatic islets and potential roles in diabetes mellitus /". Linköping : Univ, 2001. http://www.bibl.liu.se/liupubl/disp/disp2001/med655s.pdf.
Pełny tekst źródłaSörenby, Anne. "Strategies to improve macroencapsulated islet graft survival /". Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-304-7/.
Pełny tekst źródłaSkog, Oskar. "Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans". Doctoral thesis, Uppsala universitet, Klinisk immunologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172586.
Pełny tekst źródłaKsiążki na temat "Langerhans islet"
Parker, James N., i Philip M. Parker. The official patient's sourcebook on islet cell carcinoma. Redaktorzy Icon Group International Inc i NetLibrary Inc. San Diego, Calif: Icon Health Publications, 2002.
Znajdź pełny tekst źródłaPancreas, islet and stem cell transplantation for diabetes. Wyd. 2. Oxford: Oxford University Press, USA, 2010.
Znajdź pełny tekst źródłaKulkarni, Rohit N. Islet cell growth factors. Austin, Tex: Landes Bioscience, 2011.
Znajdź pełny tekst źródłaThe Pancreatic Islet Cell Transplantation Act of 2004: Report (to accompany S. 518). [Washington, D.C: U.S. G.P.O., 2004.
Znajdź pełny tekst źródłaKibenge, Molly J. Twinomwe. The relationship between the hypothalamo-pituitary-adrenal axis and the development and persistence of pancreatic islet defects in obese zucker (fa/fa) rats. Charlottetown: University of Prince Edward Island, 1994.
Znajdź pełny tekst źródłaUnited States. Congress. House. Committee on Energy and Commerce. Pancreatic Islet Cell Transplantation Act of 2004: Report (to accompany H.R. 3858) (including cost estimate of the Congressional Budget Office). [Washington, D.C: U.S. G.P.O., 2004.
Znajdź pełny tekst źródłaUnited States. Congress. House. Committee on Energy and Commerce. Pancreatic Islet Cell Transplantation Act of 2004: Report (to accompany H.R. 3858) (including cost estimate of the Congressional Budget Office). [Washington, D.C: U.S. G.P.O., 2004.
Znajdź pełny tekst źródłaUnited States. Congress. House. Committee on Energy and Commerce. Pancreatic Islet Cell Transplantation Act of 2004: Report (to accompany H.R. 3858) (including cost estimate of the Congressional Budget Office). [Washington, D.C: U.S. G.P.O., 2004.
Znajdź pełny tekst źródłaservice), SpringerLink (Online, red. The Islets of Langerhans. Dordrecht: Springer Science+Business Media B.V., 2010.
Znajdź pełny tekst źródłaIslam, Md Shahidul, red. The Islets of Langerhans. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3271-3.
Pełny tekst źródłaCzęści książek na temat "Langerhans islet"
De Bartolo, Loredana, i Antonietta Messina. "Langerhans Islet". W Encyclopedia of Membranes, 1–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-40872-4_713-1.
Pełny tekst źródłaDe Bartolo, Loredana, i Antonietta Messina. "Langerhans Islet". W Encyclopedia of Membranes, 1087–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-44324-8_713.
Pełny tekst źródłaLakey, Jonathan R. T., Lourdes Robles, Morgan Lamb, Rahul Krishnan, Michael Alexander, Elliot Botvinick i Clarence E. Foster. "Islet Encapsulation". W Islets of Langerhans, 1297–309. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6686-0_29.
Pełny tekst źródłaLa Rosa, Stefano. "Islet of Langerhans". W Encyclopedia of Pathology, 1–4. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-28845-1_5191-1.
Pełny tekst źródłaBalamurugan, A. N., Gopalakrishnan Loganathan, Amber Lockridge, Sajjad M. Soltani, Joshua J. Wilhelm, Gregory J. Beilman, Bernhard J. Hering i David E. R. Sutherland. "Islet Isolation from Pancreatitis Pancreas for Islet Autotransplantation". W Islets of Langerhans, 1199–227. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6686-0_48.
Pełny tekst źródłaHermann, Martin, Raimund Margreiter i Paul Hengster. "Human Islet Autotransplantation". W Islets of Langerhans, 1229–43. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6686-0_21.
Pełny tekst źródłaMarzorati, Simona, i Miriam Ramirez-Dominguez. "Mouse Islet Isolation". W Islets of Langerhans, 83–107. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6686-0_33.
Pełny tekst źródłaLakey, Jonathan R. T., Lourdes Robles, Morgan Lamb, Michael Alexander, Elliot Botvinick i Clarence E. Foster. "Islet Encapsulation". W Islets of Langerhans, 2. ed., 1–13. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6884-0_29-2.
Pełny tekst źródłaLakey, Jonathan R. T., Lourdes Robles, Morgan Lamb, Rahul Krishnan, Michael Alexander, Elliot Botvinick i Clarence E. Foster. "Islet Encapsulation". W Islets of Langerhans, 2. ed., 1–12. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6884-0_29-3.
Pełny tekst źródłaDrews, Gisela, Peter Krippeit-Drews i Martina Düfer. "Electrophysiology of Islet Cells". W Islets of Langerhans, 249–303. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-6686-0_5.
Pełny tekst źródłaStreszczenia konferencji na temat "Langerhans islet"
Mendoza-Elias, Joshua E., José Oberholzer i Yong Wang. "Microfluidics for Live-Cell Imaging Pancreatic Islets of Langerhans for Human Transplant". W ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting collocated with the ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/fedsm2014-21159.
Pełny tekst źródłaBanks, Dylan, Christina Morris, Joan Omeru, Wang Wei, Pantelis Georgiou i Christofer Toumazou. "A CMOS pancreatic islet of Langerhans for automatic glycemic regulation". W 2011 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2011. http://dx.doi.org/10.1109/biocas.2011.6107777.
Pełny tekst źródłaBerggren, Per-Olof. "The islet of Langerhans is a master regulator of glucose homeostasis". W 2010 IEEE Photonics Society Winter Topicals Meeting Series (WTM 2010). IEEE, 2010. http://dx.doi.org/10.1109/photwtm.2010.5421943.
Pełny tekst źródłaJansen, T., M. Buitinga, M. Boss, E. de Koning, M. Engelse, M. Nijhoff, O. Korsgren, O. Eriksson, M. Brom i M. Gotthardt. "Assessment of intrahepatic islet of Langerhans transplantation with dynamic Ga-68-NODAGA-exendin PET imaging". W NuklearMedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1683646.
Pełny tekst źródłaŠvihlík, Jan, Jan Kybic i David Habart. "Automated separation of merged Langerhans islets". W SPIE Medical Imaging, redaktorzy Martin A. Styner i Elsa D. Angelini. SPIE, 2016. http://dx.doi.org/10.1117/12.2216798.
Pełny tekst źródłaŠvihlík, Jan, Jan Kybic, David Habart, Zuzana Berková, Peter Girman, Jan Kříž i Klára Zacharovová. "Classification of microscopy images of Langerhans islets". W SPIE Medical Imaging, redaktorzy Sebastien Ourselin i Martin A. Styner. SPIE, 2014. http://dx.doi.org/10.1117/12.2043621.
Pełny tekst źródłaSouth, Jack C. M., i William J. Gullick. "Abstract C48: The role of the neuregulins and their receptors in the islets of Langerhans". W Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/1535-7163.targ-09-c48.
Pełny tekst źródłaSchönecker, S., KH Boven i U. Kraushaar. "Beta-Screen: Non-invasive and easy to use MEA-based parallelized screening system for intact islets of Langerhans". W Late breaking Abstracts – Diabetes Kongress 2018 – 53. Jahrestagung der DDG. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1657802.
Pełny tekst źródłaNieto-Chaupis, Huber. "Frequency-Based Releasing of Insulin in the Langerhans Islets To Counteract the Beginning of the Type-2 Diabetes in Pre-diabetes Patients". W 2019 IEEE 9th Annual Computing and Communication Workshop and Conference (CCWC). IEEE, 2019. http://dx.doi.org/10.1109/ccwc.2019.8666461.
Pełny tekst źródłaHusen, Saikhu Akhmad, Salamun, Arif Nur Muhammad Ansori, Raden Joko Kuncoroningrat Susilo, Suhailah Hayaza i Dwi Winarni. "The Effect of Alpha-mangostin in Glucose Level, Cholesterol Level, and Diameter of the Islets of Langerhans of STZ-induced Diabetic Mice". W 2nd International Conference Postgraduate School. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0007547005610566.
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