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1

Stefan, Peter. "Large scale in vitro expansion of mesenchymal stem cells." Thesis, University of Sheffield, 2010. http://etheses.whiterose.ac.uk/14976/.

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Mesenchymal stem cells (MSCs) can undergo self-renewal and differentiation into a variety of mature cell types. Thus, using MSCs for tissue engineering and other medical applications holds many promising advantages over normal somatic cells. However, exactly these characteristics make MSCs more difficult to grow and control in vitro. The aim of this research project was to investigate different culture systems for their utility to expand bone marrow derived MSCs in large quantities. A large scale expansion of MSCs is especially of interest since only a small number of bone marrow derived MSCs
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Hagstotz, Steffen [Verfasser], and Jochen [Akademischer Betreuer] Weller. "Large-scale structure probes of accelerated expansion / Steffen Hagstotz ; Betreuer: Jochen Weller." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1170582796/34.

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Wu, Zhi. "Transmission expansion planning and unit commitment with large-scale integration of wind power." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6738/.

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The large-scale integration of wind generation into the power system brings great challenges to transmission expansion planning (TEP) and unit commitment (UC). The intermittence nature of wind generation needs to be fully considered in these two problems, which stimulates the research of this thesis. The selection of candidate lines is the prerequisite for the TEP problem. Considering the limitations of manual selection approach, a method to select candidate lines automatically is proposed, which consists of five stages to reinforce existing corridors and new corridors. Results of the two test
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Kallos, Michael Scott. "The development of bioreactor protocols for the large scale expansion of mammalian neural stem cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0030/NQ38480.pdf.

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Fitiwi, Desta Zahlay. "Strategies, Methods and Tools for Solving Long-term Transmission Expansion Planning in Large-scale Power Systems." Doctoral thesis, KTH, Skolan för elektro- och systemteknik (EES), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192363.

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Driven by a number of factors, the electric power industry is expected to undergo a paradigm shift with a considerably increased level of variable energy sources. A significant integration of such sources requires heavy transmission investments over geographically wide and large-scale networks. However, the stochastic nature of such sources, along with the sheer size of network systems, results in problems that may become intractable. Thus, the challenge addressed in this work is to design efficient and reasonably accurate models, strategies and tools that can solve large-scale TEP problems un
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Lanier, Alan Boyd. "Irrigation cost models to assess the feasibility and potential expansion of large-scale riparian irrigation in Virginia." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-11072008-063330/.

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Ntelis, Pierros. "Probing Cosmology with the homogeneity scale of the universe through large scale structure surveys." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCC200/document.

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Cette thèse présente ma contribution à la mesure de l’échelle d’homogénéité à l’aide de galaxies, avec l’interprétation cosmologique des résultats. En physique, tout modèle est constitué par un ensemble de principes. La plupart des modèles de cosmologie sont basés sur le principe cosmologique, qui indique que l’univers est statistiquement homogène et isotrope à grande échelle. Aujourd’hui, ce principe est considéré comme vrai car il est respecté par ces modèles cosmologiques qui décrivent avec précision les observations. Cependant, l’isotropie de l’univers est maintenant confirmée par de nombr
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Øren, Lars Pedersen. "System Analysis of Large-Scale Wind Power Integration in North-Western Europe : A study on the impact of large-scale wind power expansion and on the impact of a North Sea offshore grid." Thesis, Norwegian University of Science and Technology, Department of Electrical Power Engineering, 2009. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-9020.

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<p>Problem description: The objective of this project was to create a simple model of the European power system and to investigate the effect an increasing amount of on- and offshore wind power will have on the North European power market in general and Norway in particular. The scenarios contain increasing amounts of installed wind power capacity, both on- and offshore. Emphasis was to be on the area surrounding the North Sea. The project covers the following issues: - Simulations of simplified power system scenarios set in the years 2005, 2020 and 2030. - Study how an increasing amount of i
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Corrales, Duque Carolina. "Population Genetic Structure of Black Grouse (Tetrao tetrix) : From a Large to a Fine Scale Perspective." Doctoral thesis, Uppsala universitet, Institutionen för ekologi och genetik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-150117.

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Black grouse (Tetrao tetrix) is a bird species with a lek mating system found in the Palearctic boreal taiga. It is assumed that it has a continuous distribution along Scandinavia and Siberia, whereas in Central Europe it has declined during the last decades. The primary objective of this thesis was to obtain a deeper understanding of the history, systematic classification and the genetic structure of black grouse on different geographical scales using microsatellites and control region mtDNA sequences (CR). I determined how much the mating system, habitat fragmentation and historical populati
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10

Comparat, Johan. "Baryonic acoustic oscillations with emission line galaxies at intermediate redshift : the large-scale structure of the universe." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4720/document.

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J'ai démontrer la faisabilité de la sélection de la cible pour les galaxies en ligne des émissions lumineuses. Je comprends maintenant les principaux mécanismes physiques de conduite de l'efficacité d'une sélection, en particulier le rapport à la photométrie de parent. Une question reste perplexe, je ne pouvais pas encore estimer quantitativement l'impact de la poussière sur l'efficacité de la sélection. J'espère que d'aborder cette question avec l'ensemble des données décrites dans le chapitre 4.En dehors de la ligne de sélection de la cible de la galaxie d'émission, j'ai étudié, au premier o
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Alimi, Jean-Michel. "Contributions : instabilite gravitationnelle dans un univers en expansion et formation des grandes structures, effets ponderomoteurs dans les plasmas magnetises." Paris 6, 1987. http://www.theses.fr/1987PA066234.

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Analyse de la fonction de correlation spatiale des galaxies, obtenue a partir de catalogues de galaxies, selon differentes procedures. La distribution des galaxies isolees dans le catalogue cfa est etudiee. Etude du collapse gravitationnel non lineaire de particules sans collision, du point de vue analytique et numerique. On montre l'importance du traitement tridimensionnel de ces processus gravitationnels et quelles peuvent en etre les consequences sur la formation des galaxies
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Schesser, Derek G. "Mechanics of Expanding Grout Based Grips for Large Scale Composites Testing." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_theses/298.

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Experimental testing of large composite specimens under tension or shear is inherently challenging because the large required gripping force and resulting local stress concentration tend to break specimens near gripping sites, rather than desired gage sections. A method using expansive grout materials has been proposed since the mid 1990’s. However, there has been no well-established design guideline due to lack of understanding of the gripping pressure developed by the expansive grout material. Key properties including the elastic modulus and linear expansion coefficient are difficult to meas
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Leuthold, Florian U. "Economic Engineering Modeling of Liberalized Electricity Markets: Approaches, Algorithms, and Applications in a European Context." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-26135.

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This dissertation focuses on selected issues in regard to the mathematical modeling of electricity markets. In a first step the interrelations of electric power market modeling are highlighted a crossroad between operations research, applied economics, and engineering. In a second step the development of a large-scale continental European economic engineering model named ELMOD is described and the model is applied to the issue of wind integration. It is concluded that enabling the integration of low-carbon technologies appears feasible for wind energy. In a third step algorithmic work is carri
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14

"Transmission Expansion Planning with Large Scale Renewable Resource Integration." Master's thesis, 2012. http://hdl.handle.net/2286/R.I.14503.

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abstract: Due to economic and environmental reasons, several states in the United States of America have a mandated renewable portfolio standard which requires that a certain percentage of the load served has to be met by renewable resources of energy such as solar, wind and biomass. Renewable resources provide energy at a low variable cost and produce less greenhouse gases as compared to conventional generators. However, some of the complex issues with renewable resource integration are due to their intermittent and non-dispatchable characteristics. Furthermore, most renewable resources are l
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15

Tran, Van-Tan, and 陳文進. "Optimal Transmission Expansion Planning Considering the System Impacts from Integration of Large-scale Wind Farms." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/72117778418090212715.

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博士<br>國立臺灣科技大學<br>電機工程系<br>103<br>In recent year, there has been an increasing interest in renewable energy, such as wind, solar, biomass, ocean, geothermal and so on. Among them wind power play an importance role. So that, this dissertation investigated the optimal transmission expansion planning considering the system impacts from integration of large-scale wind farms. The concerned system impacts include economic and transient stability of the interconnected power transmission network. First, a method based on graph theory was proposed for transmission network expansion planning (TNEP). The
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16

"Large Scale Expansion and Differentiation of Human Pluripotent Stem Cell-Derived Neural Progenitor Cells (hNPCs)." Master's thesis, 2017. http://hdl.handle.net/2286/R.I.44021.

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abstract: Neurodegenerative diseases such as Alzheimer’s Disease, Parkinson’s Disease and Amyotrophic Lateral Sclerosis are marked by the loss of different types of neurons and glial cells in the central nervous system (CNS). Human Pluripotent Stem Cell (hPSC)-derived Neural Progenitor Cells (hNPCs) have the ability to self-renew indefinitely and to differentiate into various cell types of the CNS. HNPCs can be used in cell based therapies and have the potential to reverse or arrest neurodegeneration and to replace lost neurons and glial cells. However, the lack of completely defined, scalable
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"An Integrated Biomanufacturing Platform for the Large-Scale Expansion and Differentiation of Neural Progenitor Cells." Master's thesis, 2018. http://hdl.handle.net/2286/R.I.49398.

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abstract: Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, or amyotrophic lateral sclerosis are defined by the loss of several types of neurons and glial cells within the central nervous system (CNS). Combatting these diseases requires a robust population of relevant cell types that can be employed in cell therapies, drug screening, or patient specific disease modeling. Human induced pluripotent stem cells (hiPSC)-derived neural progenitor cells (hNPCs) have the ability to self-renew indefinitely and differentiate into the various neuronal and glial cell types of th
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18

Mondal, Anirban. "Bayesian Uncertainty Quantification for Large Scale Spatial Inverse Problems." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9905.

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We considered a Bayesian approach to nonlinear inverse problems in which the unknown quantity is a high dimension spatial field. The Bayesian approach contains a natural mechanism for regularization in the form of prior information, can incorporate information from heterogeneous sources and provides a quantitative assessment of uncertainty in the inverse solution. The Bayesian setting casts the inverse solution as a posterior probability distribution over the model parameters. Karhunen-Lo'eve expansion and Discrete Cosine transform were used for dimension reduction of the random spatial field.
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19

"Performance comparison of conjugate gradient density matrix search and Chebyshev expansion methods for avoiding diagonalization in large-scale electronic structure calculations." Thesis, 1998. http://hdl.handle.net/1911/20474.

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We report a performance comparison of two linear-scaling methods which avoid the diagonalization bottleneck of traditional electronic structure algorithms. The Chebyshev expansion method (CEWI) is implemented for carbon tight-binding calculations of large systems and its memory and timing requirements compared to those of our previously implemented conjugate gradient density matrix search (CG-DMS). Benchmark calculations are carried out on icosahedral fullerenes from C60 to C8640 and the linear scaling memory and CPU requirements of CEM demonstrated. We show that the CPU requisites of CEM and
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20

Leuthold, Florian U. "Economic Engineering Modeling of Liberalized Electricity Markets: Approaches, Algorithms, and Applications in a European Context: Economic Engineering Modeling of Liberalized Electricity Markets: Approaches, Algorithms, and Applications in a European Context." Doctoral thesis, 2009. https://tud.qucosa.de/id/qucosa%3A25185.

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This dissertation focuses on selected issues in regard to the mathematical modeling of electricity markets. In a first step the interrelations of electric power market modeling are highlighted a crossroad between operations research, applied economics, and engineering. In a second step the development of a large-scale continental European economic engineering model named ELMOD is described and the model is applied to the issue of wind integration. It is concluded that enabling the integration of low-carbon technologies appears feasible for wind energy. In a third step algorithmic work is carri
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