Gotowe bibliografie tematyczne / Late functionalization

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  1. Artykuły w czasopismach
  2. Rozprawy doktorskie
  3. Książki
  4. Części książek
  5. Streszczenia konferencji

Gotowa bibliografia na temat „Late functionalization”

Autor: Grafiati
Data publikacji: 7 września 2024
Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Late functionalization"

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Börgel, Jonas, and Tobias Ritter. "Late-Stage Functionalization." Chem 6, no. 8 (2020): 1877–87. http://dx.doi.org/10.1016/j.chempr.2020.07.007.

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McConnell, Cameron R., and Shih-Yuan Liu. "Late-stage functionalization of BN-heterocycles." Chemical Society Reviews 48, no. 13 (2019): 3436–53. http://dx.doi.org/10.1039/c9cs00218a.

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Bellina, Fabio. "Late-stage Functionalization of (hetero)arenes." Current Organic Chemistry 25, no. 18 (2021): 2045. http://dx.doi.org/10.2174/138527282518211007142734.

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Miller, Scott J., and Tobias Ritter. "Introduction: Remote and Late Stage Functionalization." Chemical Reviews 123, no. 24 (2023): 13867–68. http://dx.doi.org/10.1021/acs.chemrev.3c00800.

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Son, Jongwoo. "Sustainable manganese catalysis for late-stage C–H functionalization of bioactive structural motifs." Beilstein Journal of Organic Chemistry 17 (July 26, 2021): 1733–51. http://dx.doi.org/10.3762/bjoc.17.122.

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The late-stage C–H functionalization of bioactive structural motifs is a powerful synthetic strategy for accessing advanced agrochemicals, bioimaging materials, and drug candidates, among other complex molecules. While traditional late-stage diversification relies on the use of precious transition metals, the utilization of 3d transition metals is an emerging approach in organic synthesis. Among the 3d metals, manganese catalysts have gained increasing attention for late-stage diversification due to the sustainability, cost-effectiveness, ease of operation, and reduced toxicity. Herein, we sum
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Kumar Hota, Sudhir, Dilsha Jinan, Satya Prakash Panda, Rittwika Pan, Basudev Sahoo, and Sandip Murarka. "Organophotoredox‐Catalyzed Late‐Stage Functionalization of Heterocycles." Asian Journal of Organic Chemistry 10, no. 8 (2021): 1848–60. http://dx.doi.org/10.1002/ajoc.202100234.

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Cernak, Tim, Kevin D. Dykstra, Sriram Tyagarajan, Petr Vachal, and Shane W. Krska. "The medicinal chemist's toolbox for late stage functionalization of drug-like molecules." Chemical Society Reviews 45, no. 3 (2016): 546–76. http://dx.doi.org/10.1039/c5cs00628g.

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The advent of modern C–H functionalization chemistries has enabled medicinal chemists to consider a synthetic strategy, late stage functionalization (LSF), which utilizes the C–H bonds of drug leads as points of diversification for generating new analogs.
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Greaney, Michael F., and David M. Whalley. "Recent Advances in the Smiles Rearrangement: New Opportunities for Arylation." Synthesis 54, no. 08 (2021): 1908–18. http://dx.doi.org/10.1055/a-1710-6289.

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AbstractThe Smiles rearrangement has undergone a renaissance in recent years providing new avenues for non-canonical arylation techniques in both the radical and polar regimes. This short review will discuss recent applications of the reaction (from 2017 to late 2021), including its relevance to areas such as heterocycle synthesis and the functionalization of alkenes and alkynes as well as glimpses at new directions for the field.1 Introduction2 Polar Smiles Rearrangements3 Radical Smiles: Alkene and Alkyne Functionalization4 Radical Smiles: Rearrangements via C–X Bond Cleavage5 Radical Smiles
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Barham, Joshua P., та Jaspreet Kaur. "Site-Selective C(sp3)–H Functionalizations Mediated by Hydrogen Atom Transfer Reactions via α-Amino/α-Amido Radicals". Synthesis 54, № 06 (2021): 1461–77. http://dx.doi.org/10.1055/a-1677-6619.

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AbstractAmines and amides, as N-containing compounds, are ubiquitous in pharmaceutically-active scaffolds, natural products, agrochemicals, and peptides. Amides in nature bear a key responsibility for imparting three-dimensional structure, such as in proteins. Structural modifications to amines and amides, especially at their positions α to N, bring about profound changes in biological activity oftentimes leading to more desirable pharmacological profiles of small drug molecules. A number of recent developments in synthetic methodology for the functionalizations of amines and amides omit the n
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Čorić, Ilija, and Jyoti Dhankhar. "Introduction to Spatial Anion Control for Direct C–H Arylation." Synlett 33, no. 06 (2022): 503–12. http://dx.doi.org/10.1055/s-0040-1719860.

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AbstractC–H activation of functionally rich molecules without the need for directing groups promises shorter organic syntheses and late-stage diversification of molecules for drug discovery. We highlight recent examples of palladium-catalyzed nondirected functionalization of C–H bonds in arenes as limiting substrates with a focus on the development of the concept of spatial anion control for direct C–H arylation.1 C–H Activation and the CMD Mechanism2 Nondirected C–H Functionalizations of Arenes as Limiting Substrates3 Nondirected C–H Arylation4 Spatial Anion Control for Direct C–H Arylation5
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Rozprawy doktorskie na temat "Late functionalization"

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Brown, Alec Nathaniel. "Late-Stage Functionalization of 1,2-Dihydro-1,2-Azaborines." Thesis, Boston College, 2015. http://hdl.handle.net/2345/bc-ir:104564.

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Thesis advisor: Shih-Yuan Liu<br>Described herein are two distinct research projects focused on the development of metal-catalyzed late-stage functionalization strategies for 1,2-dihydro-1,2-azaborines separated into three chapters. The first chapter discusses the development, synthesis, and recent contributions to the field of azaborine chemistry. The second chapter details the development of rhodium catalyzed B-H bond activation for the synthesis of a new class of BN-stilbenes as well as the discovery of a novel B-H to B-Cl transformation that is successful both with B-H azaborines as well a
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Canelli, Tommaso. "Development of tandem C-H borylation/functionalization procedures for late stage functionalization of compounds." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9273/.

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The development of procedures for the iridium catalyzed C-H borylation of 1-aryl pyrazolopyrimidines and 1-aryl indazoles is reported. Investigation on the activity of the catalyst revealed the combination of an iridium (I) precursor and tetramethylphenantroline as the best catalytic system. Moreover, the procedures are regioselective resulting in the selective borylation of different C-H bonds within the substrates. The application of C-H borylation to late stage functionalization is demonstrated: a biologically active compound in AstraZeneca's project underwent tandem borylation/oxidation re
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Bentley, Sierra Kathleen. "Selective Direct Borylation and Late-Stage Functionalization of 1,2-Azaborines:." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:109014.

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Thesis advisor: Shih-Yuan Liu<br>Described herein is the development of a method to directly borylate the C5-position of monocyclic 1,2-azaborines without the use of a metal catalyst, kinetic resolution or directing group. This method tolerates different substitution on the boron as well as at the C3-position of the azaborine. A new BN-isostere of the drug molecule, felbinac, was synthesized to demonstrate the application of this method<br>Thesis (MS) — Boston College, 2020<br>Submitted to: Boston College. Graduate School of Arts and Sciences<br>Discipline: Chemistry
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Kaplaneris, Nikolaos [Verfasser]. "Resource-Economical C–H Activation for Late-Stage Functionalization / Nikolaos Kaplaneris." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1237128854/34.

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Armand, Jeremy Richard. "Late Stage Functionalization of 1,2-Azaborines for Application in Biomedical Research:." Thesis, Boston College, 2019. http://hdl.handle.net/2345/bc-ir:108646.

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Thesis advisor: Shih-Yuan . Liu<br>Chapter 1. Use of boron as a pharmacophore is as growing but still underdeveloped strategy for expanding chemical space in biomedical research. In addition to more established methods of incorporating boron in drug development, an attractive and emerging method of introducing boron into biologically active compounds is through boron-nitrogen containing heterocycles. In particular, the Liu group has focused on exploring the interactions of monocyclic 1,2-azaborines in biological space. In order to install complicated chemical functionality needed for further s
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Chan, Jessica Zee. "Stereoselective Functionalization of Carbonyl Compounds and N-Alkylamines Promoted by Cooperative Catalysts:." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:108940.

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Thesis advisor: Masayuki Wasa<br>This dissertation describes the development of cooperative catalyst systems for the functionalization of monocarbonyl compounds and stereoselective transformations of alpha-C–H bonds of N-alkylamines, inspired by the concepts of frustrated Lewis pairs (FLPs). Prior to this dissertation research, practical and broadly applicable C–C and C–heteroatom bond forming reactions involving the FLP complexes that provide synthetically desirable products with high enantioselectivity remained to be developed. Chapter 1 of this dissertation describes the recent advances in
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Schischko, Alexandra. "Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E4F4-0.

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Zhang, Zhuan. "Late Stage Modifications of Phosphines using Transition-Metal-Catalyzed C–H Bond Functionalization." Thesis, Rennes, Ecole nationale supérieure de chimie, 2020. http://www.theses.fr/2020ENCR0067.

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L'objectif principal de cette thèse de doctorat porte sur la préparation de phosphines polyfonctionnelles par diversification tardive de ligands commerciaux. Nous avons développé l'alkylation la liaison C–H en position ortho' des biarylphosphines catalysée par le rhodium(I). Cette nouvelle méthodologie permet d'accéder facilement à une vaste bibliothèque de phosphines multifonctionnelles. Certains de ces ligands modifiés ont surpassé les phosphines disponibles dans le commerce dans la carboxylation des bromures d'aryle catalysée par le palladium avec du dioxyde de carbone en présence d'un cata
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Poudel, Dhruba P. "Late-Stage Modification of Polyurethane Dendrimers Using Click Chemistry." Miami University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=miami1627490978861964.

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Hanson, Susan Kloek. "Synthesis and reactivity studies of late transition metal complexes relevant to C-H bond activation and functionalization /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8631.

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Książki na temat "Late functionalization"

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Koepnick, Lutz. Culture in the Shadow of Trauma? Edited by Helmut Walser Smith. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780199237395.013.0031.

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In the ruins of World War II, culture was meant to mend the spiritual wounds and traumatic losses of everyday life by providing meanings and orientations unscathed by the functionalization of aesthetic culture during the Nazi era. This article focuses on the culture ballgame cast under the shadow of trauma raged by the war and its aftermath. Art, literature, theater, film, and music, in both emerging Germanys, were no doubt embraced as conduits for a resurrection of the spirit. However, the traumas left by the immediate past led artistic practitioners and their recipients alike to believe that
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Części książek na temat "Late functionalization"

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Fujiwara, Yuta, and Phil S. Baran. "Radical-Based Late Stage C–H Functionalization of Heteroaromatics in Drug Discovery." In New Horizons of Process Chemistry. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3421-3_8.

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Noisier, Anaïs F. M., and Ranganath Gopalakrishnan. "Oxime/Hydrazone Conjugation at Histidine: Late-Stage Functionalization Approach of Unprotected Peptides." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1617-8_4.

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Pal, Sunit, and Peter ‘t Hart. "Late-Stage Functionalization of Peptides on Solid-Phase via Photochemical Decarboxylative Arylation." In Methods in Molecular Biology. Springer US, 2025. https://doi.org/10.1007/978-1-0716-4578-9_10.

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Klopsch, Isabel, Ekaterina Yu Yuzik-Klimova, and Sven Schneider. "Functionalization of N2 by Mid to Late Transition Metals via N–N Bond Cleavage." In Nitrogen Fixation. Springer International Publishing, 2017. http://dx.doi.org/10.1007/3418_2016_12.

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Friis, Stig D., Erik Weis, and Magnus J. Johansson. "HTE as a Tool in C–H Activation Reaction Discovery and Late-Stage Functionalization of Pharmaceuticals." In The Power of High-Throughput Experimentation: Case Studies from Drug Discovery, Drug Development, and Catalyst Discovery (Volume 2). American Chemical Society, 2022. http://dx.doi.org/10.1021/bk-2022-1420.ch010.

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Tayeb, Azmil. "Overview of state functionalization of national education in Indonesia and Malaysia from the late 1800s to the present." In Islamic Education in Indonesia and Malaysia. Routledge, 2018. http://dx.doi.org/10.4324/9781351116862-2.

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Prato, Maurizio, Michele Maggini, and Gianfranco Scorrano. "Organic Functionalization of Fullerenes: Toward Materials and Biological Applications." In The Chemical Physics of Fullerenes 10 (and 5) Years Later. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-015-8682-5_19.

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Düsenberg, Björn, Juan Sebastian Gomez Bonilla, Marius Christ, et al. "Gas Phase Functionalization of Polymer and Metallic Materials for Powder-Based Additive Manufacturing." In Springer Tracts in Additive Manufacturing. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-78350-0_3.

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Abstract The majority of commercially available particulate materials in additive manufacturing are single-material systems. Multi-material systems are typically generated by bulk mixing as heterogeneous systems that are difficult to reproduce due to segregation effects during mixing and later deposition in the manufacturing process. This limits the properties of the additively manufactured components. For further application areas of additively manufactured components, it is therefore imperative to produce process-optimized single-material particles in addition to multi-material systems, wher
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Rubin, Yves. "Recent Aspects of the Functionalization Chemistry of Buckminsterfullerene (C60): Preparation of New materials and compounds of Biological Interest." In The Chemical Physics of Fullerenes 10 (and 5) Years Later. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-015-8682-5_20.

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Sberegaeva, Anna V., David Watts, and Andrei N. Vedernikov. "Oxidative Functionalization of Late Transition Metal–Carbon Bonds." In Advances in Organometallic Chemistry. Elsevier, 2017. http://dx.doi.org/10.1016/bs.adomc.2017.03.001.

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Streszczenia konferencji na temat "Late functionalization"

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Zhang, Meng-Qian, and Yan-Mei Li. "A Rapid and Efficient Photochemical Modification Strategy for Late-Stage Peptide and Protein Functionalization." In 37th European Peptide Symposium. The European Peptide Society, 2024. http://dx.doi.org/10.17952/37eps.2024.p2005.

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Ahmad, Asad, Nathan Gallant, Rasim Guldiken, and Onursal Onen. "Surface Functionalization of an Ovarian Cancer Diagnostic Biosensor." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64311.

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Ovarian cancer is the fifth leading cause of death among women in United States and the disease has 1.4% (1 in 71) lifetime risk. Patients with ovarian cancer have a short median survival time after diagnosis with their 5-year survival rate being less than 40%. Early stage ovarian cancer represents an important target for screening since it is lethal in most late stage cases (1). Currently the primary screening procedure for ovarian cancer are blood levels of cancer antigen (CA) 125, however CA 125 levels can also be elevated due to other disorders and do not provide conclusive results (2). Ut
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Ballantine, Ross D., Mingxiang Zhu, Ameni Hadj Mohamed, et al. "Palladium-mediated S-arylation and S-allylation for late stage peptide functionalization and protein conjugation." In 37th European Peptide Symposium. The European Peptide Society, 2024. http://dx.doi.org/10.17952/37eps.2024.p2010.

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Kulcitki, Veaceslav, Catalina Cazacu, Olga Morarescu, et al. "Late stage functionalization of unactivated C-H bonds in terpenes – a fruitful field for free radical chemistry." In New frontiers in natural product chemistry, scientific seminar with international participation. Institute of Chemistry, 2021. http://dx.doi.org/10.19261/nfnpc.2021.ab13.

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Birca, Natalia, and Veaceslav Kulcitki. "Late stage functionalization of cyclic terpenoids by atom transfer radical addition. A convenient route towards nitrogen heterocycles." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab12.

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Terpens are a class of widely spread natural compounds with a broad range of biological properties, showing ‘drug-like’ chemical properties, including lipophilicity, interesting molecular geometry, alkylating center reactivity etc [1]. Nevertheless, nitrogen-containing terpens, which can show diverse functionality and biological activity in living cells, are rare in natural sources. We present in this communication the atom transfer radical additions performed on relevant terpene derivatives of labdane and drimane framework, compounds 1-3, and resulting in a series of azido-compounds. Carboazi
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fruit, corinne, thierry besson, Marine Harari, and Florence Couly. "Late-Stage Sequential C-H Functionalization of Thiazolo[5,4-f]quina-zolin-9(8H)-one: Synthesis of a Library of Potential Kinase Inhibitors." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b002.

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Lasagni, Andrés, Teja Roch, Matthias Bieda, Dimitri Benke та Eckhard Beyer. "High speed surface functionalization using direct laser interference patterning, towards 1 m2/min fabrication speed with sub-μm resolution". У SPIE LASE, редактори Udo Klotzbach, Kunihiko Washio та Craig B. Arnold. SPIE, 2014. http://dx.doi.org/10.1117/12.2041215.

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Bittigkoffer, Lucas, Henry Roth, Martin Baumann, and Nils-Agne Feth. "Surface Functionalization of Nitinol Utilizing Ultrashort Laser Pulses." In SMST 2024. ASM International, 2024. http://dx.doi.org/10.31399/asm.cp.smst2024p0129.

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Abstract Ultrashort pulse (USP) lasers are an established technology to manufacture nitinol medical devices. USP lasers offer a great variety of processing parameters which can be utilized for fine cutting, laser lathe and ablation of nitinol. Usually, several hundreds of kHz are used to penetrate the material with pulses of fixed energy and frequency. New USP laser sources are offering a so-called burst mode which can be used to precisely control the energy deposition into the material by adjusting the temporal pulse distribution. Depending on the applied process parameters, this leads to a c
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Kowalczyk, T. C., T. Z. Kosc, K. D. Singer, et al. "Guest-Host Crosslinked Polyimides for Integrated Optics." In Organic Thin Films for Photonic Applications. Optica Publishing Group, 1995. http://dx.doi.org/10.1364/otfa.1995.md.11.

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We report on our approach to the development of device-quality electro-optic materials. We have sought to optimize the optical losses and processing properties first, and later to functionalize the materials having learned how to synthesize and process them for devices. [1,2] We started with perfluorinated, preimidized fully aromatic polyimides. Preimidization makes processing doped polymer systems more flexible, by making functionalizing easier (no harsh imidization process) while allowing spin coating of soluble fully-imidized polymers. Fluorination increases solubility while decreasing opti
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