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Artykuły w czasopismach na temat "LEVERAGING DISRUPTIONS"
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Lee, Jane, Lavanya Marla, and Alexandre Jacquillat. "Dynamic Disruption Management in Airline Networks Under Airport Operating Uncertainty." Transportation Science 54, no. 4 (2020): 973–97. http://dx.doi.org/10.1287/trsc.2020.0983.
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Air traffic disruptions result in flight delays, cancellations, passenger misconnections, and ultimately high costs to aviation stakeholders. This paper proposes a jointly reactive and proactive approach to airline disruption management, which optimizes recovery decisions in response to realized disruptions and in anticipation of future disruptions. The approach forecasts future disruptions partially and probabilistically by estimating systemic delays at hub airports (and the uncertainty thereof) and ignoring other contingent disruptions. It formulates a dynamic stochastic integer programming framework to minimize network-wide expected disruption recovery costs. Specifically, our Stochastic Reactive and Proactive Disruption Management (SRPDM) model combines a stochastic queuing model of airport congestion, a flight planning tool from Boeing/Jeppesen and an integer programming model of airline disruption recovery. We develop a solution procedure based on look-ahead approximation and sample average approximation, which enables the model’s implementation in short computational times. Experimental results show that leveraging even partial and probabilistic estimates of future disruptions can reduce expected recovery costs by 1%–2%, as compared with a myopic baseline approach based on realized disruptions alone. These benefits are mainly driven by the deliberate introduction of departure holds to reduce expected fuel costs, flight cancellations, and aircraft swaps.
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Birkie, Seyoum Eshetu, Paolo Trucco, and Pablo Fernandez Campos. "Effectiveness of resilience capabilities in mitigating disruptions: leveraging on supply chain structural complexity." Supply Chain Management: An International Journal 22, no. 6 (2017): 506–21. http://dx.doi.org/10.1108/scm-01-2017-0009.
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Purpose This study aims to investigate the influence of supply chain (SC) complexity on the effectiveness of resilience capabilities in mitigating SC disruptions. Hypotheses about direct and moderating influences of complexity on resilience capabilities and performance change after disruption are built and quantitatively tested. Design/methodology/approach Partial least square-based structural equation modelling with formative constructs was used as an overall approach. Secondary data on SC disruptions, related performance change and resilience practices were collected from multiple sources through a predefined procedure. The collected data were systematically encoded prior to performing statistical analysis. Findings SC structural complexity is found to have a significant positive relation with performance improvement after disruption, along with resilience capability; it also positively moderates the resilience–performance link. Research limitations/implications The SC complexity factors the authors considered in this study do not include dynamic forms because of the nature of data collected. Future research may attempt to include and test whether the results of this study also hold when additional complexity parameters are taken into account. Practical implications Managers are often trying to reduce SC complexity. This study implies that some level of complexity is beneficial also for a better recovery of operational performance affected because of disruption. Resilience capabilities become more effective when leveraged on complexity in the SC. Originality/value This is the first study to empirically investigate the influence of SC complexity on the resilience–performance link.
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Prusaczyk, Beth, Eric Lenze, Brian Carpenter, and Nancy Morrow-Howell. "Leveraging Disruptions to Create an Equitable, Age-Friendly, Learning Health System." Innovation in Aging 5, Supplement_1 (2021): 290. http://dx.doi.org/10.1093/geroni/igab046.1124.
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Abstract In a learning health system, the system’s own data and the experiences of its workforce are integrated with external evidence to provide better care. In an age-friendly health system, core principles of age-friendly care are integrated into every point in the system. Disruptions caused by the COVID-19 pandemic, and the innovations that addressed them, present an opportunity to discuss how these two frameworks may be combined and leveraged to transform care for older adults. We will present examples of pandemic-related disruptions, including rapid changes in how patients and providers move within and between facilities and the significant toll on healthcare workers’ mental health. We will also highlight innovative solutions to these disruptions that could transform healthcare systems. Critical to these points is a discussion of how these disruptions have disproportionately impacted healthcare workers and patients of color and how the innovations must be implemented using an anti-racist, health equity lens.
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Verghese, Anto, Xenophon Koufteros, and Baofeng Huo. "Leveraging customer benevolence for resilience: a supplier perspective." International Journal of Physical Distribution & Logistics Management 49, no. 7 (2019): 727–48. http://dx.doi.org/10.1108/ijpdlm-06-2018-0217.
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PurposeWith more than half of customer-experienced disruptions attributed to first-tier suppliers, supplier resilience (SRES) is fundamental to the resilience of the supply chain. However, little is known about the relational aspects that engender SRES, from the purview of the supplier. The purpose of this paper is to examine the explanatory role of suppliers’ relationship commitment dimensions (i.e. affective and continuance), which may foster SRES through customer benevolence. Moreover, the impact of customer benevolence on SRES is examined considering varying levels of industry dynamism.Design/methodology/approachSurvey data from 207 manufacturing firms are utilized to test the hypotheses taking potential endogeneity issues into consideration.FindingsAffective and continuance commitment induce customer benevolence, which furthers SRES. Specifically, affective commitment is the most potent approach to induce customer benevolence, while the dampening effect of industry dynamism is more palpable at the higher levels of industry dynamism.Research limitations/implicationsThis study did not account for specific disruption types and the contingent effects of power asymmetry.Practical implicationsThis study empirically demonstrates that suppliers can leverage customer benevolence via relationship commitment to achieve SRES. However, the efficacy of customer benevolence to engender SRES is limited to environments not characterized by high levels of industry dynamism.Originality/valueThis paper highlights the role of relational mechanisms in achieving resilience from the purview of a supplier using survey data.
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Sincorá, Larissa Alves, Marcos Paulo Valadares de Oliveira, Hélio Zanquetto-Filho, and Marcelo Bronzo Ladeira. "Business analytics leveraging resilience in organizational processes." RAUSP Management Journal 53, no. 3 (2018): 385–403. http://dx.doi.org/10.1108/rausp-04-2018-002.
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Purpose The survival and growth of organizations presently depend on managing processes and capabilities to effectively use large volumes of data from different sources to assist organizations’ strategic and operational goals. This paper aims to test the relationship between organizational analytical capabilities (OAC), the performance results in organizational resilience (OR) and the business process management maturity (BPMM). Design/methodology/approach Based on a survey of companies operating in the state of Espírito Santo, Brazil, a conceptual model was proposed and tested using the partial least squares algorithm. Findings The results confirm the proposed theoretical hypotheses that OAC and BPMM positively impact OR. In addition, the results show that OAC exert a moderating effect on the relationship between BPMM and OR. Practical implications It is understood that stimulating the practice of data and information analysis in the organizational routine translates into a relevant managerial behavior, as this attitude leverages the knowledge development and understanding about how to manage unexpected risk events, enabling companies to assess their ability to react to disruptions, even in terms of operational failures.
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Bulgart, Hannah R., Isabella Goncalves, and Noah Weisleder. "Leveraging Plasma Membrane Repair Therapeutics for Treating Neurodegenerative Diseases." Cells 12, no. 12 (2023): 1660. http://dx.doi.org/10.3390/cells12121660.
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Plasma membrane repair is an essential cellular mechanism that reseals membrane disruptions after a variety of insults, and compromised repair capacity can contribute to the progression of many diseases. Neurodegenerative diseases are marked by membrane damage from many sources, reduced membrane integrity, elevated intracellular calcium concentrations, enhanced reactive oxygen species production, mitochondrial dysfunction, and widespread neuronal death. While the toxic intracellular effects of these changes in cellular physiology have been defined, the specific mechanism of neuronal death in certain neurodegenerative diseases remains unclear. An abundance of recent evidence indicates that neuronal membrane damage and pore formation in the membrane are key contributors to neurodegenerative disease pathogenesis. In this review, we have outlined evidence supporting the hypothesis that membrane damage is a contributor to neurodegenerative diseases and that therapeutically enhancing membrane repair can potentially combat neuronal death.
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Liu, Hua, and Shaobo Wei. "Leveraging interorganizational governance for bridging responses to supply chain disruptions: a polynomial regression analysis." International Journal of Operations & Production Management 41, no. 8 (2021): 1350–78. http://dx.doi.org/10.1108/ijopm-07-2020-0480.
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PurposeDrawing on the transactional cost economics (TCE) perspective, we aim to investigate the effects of the balance and imbalance between contractual and relational governance on a firm's bridging responses to supply chain disruptions. By adopting the institutionally contingent perspective, we further examine the moderating effect of cultural distance on the relationship between governance mechanisms and bridging responses.Design/methodology/approachBased on data collected from 183 firms in China, we use polynomial regression and response surface analyses to test our research model.FindingsThe bridging responses increase along with an increasing balance level between contractual and relational governance and decrease along with an increasing imbalance level between contractual and relational governance. Moreover, the positive effect of balance between contractual and relational governance is strengthened by a large cultural distance. We also find that a large cultural distance amplifies the negative effect of the combination of high relational governance and low contractual governance yet weakens that of the combination of high contractual governance and low relational governance.Originality/valueOur study provides nuanced insights into the effects of the balance and imbalance between contractual and relational governance on bridging responses and into the cultural boundary conditions under which these effects vary.
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Dahiya, Shikha, Kevin James, Kandarp Patel, Aditi Pathak, and Anoop Singh. "India’s Human Capital: The Regulatory Context for Leveraging Federalism." Indian Public Policy Review 2, no. 5 (Sep-Oct) (2021): 1–33. http://dx.doi.org/10.55763/ippr.2021.02.05.001.
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 Investing in human capital through interventions in nutrition, health, and education is critical for achieving sustainable inclusive growth. However, despite many public interventions, India’s human capital indicators remain low, and have likely worsened from the disruptions caused by the COVID-19 pandemic. There are also significant inter-State disparities. India’s human capital interventions have been marked by growing centralisation, not just by the Centre vis-à-vis the States, but also by the States vis-à-vis local governments, that form the third tier in India’s federal structure. This growing centralisation may have misaligned incentives with respect to accountability and effective delivery of public services. Drawing from international best practices and an analysis of the constitutional scheme, a more decentralised and targeted approach within the contours of India’s federal structure may be the best way to build civil society engagement, address failures in accountability, and ultimately, improve India’s human capital outcomes.
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Bowen, Deborah J., Kelly E. Rentscher, Amy Wu, et al. "Learning from and Leveraging Multi-Level Changes in Responses to the COVID 19 Pandemic to Facilitate Breast Cancer Prevention Efforts." International Journal of Environmental Research and Public Health 18, no. 13 (2021): 6999. http://dx.doi.org/10.3390/ijerph18136999.
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The coronavirus pandemic (COVID-19) has had multilevel effects on non-COVID-19 health and health care, including deferral of routine cancer prevention and screening and delays in surgical and other procedures. Health and health care use has also been affected by pandemic-related loss of employer-based health insurance, food and housing disruptions, and heightened stress, sleep disruptions and social isolation. These disruptions are projected to contribute to excess non-COVID-19 deaths over the coming decades. At the same time municipalities, health systems and individuals are making changes in response to the pandemic, including modifications in the environmental to promote health, implementation of telehealth platforms, and shifts towards greater self-care and using remote platforms to maintain social connections. We used a multi-level biopsychosocial model to examine the available literature on the relationship between COVID-19-related changes and breast cancer prevention to identify current gaps in knowledge and identify potential opportunities for future research. We found that COVID-19 has impacted several aspects of social and economic life, through a variety of mechanisms, including unemployment, changes in health care delivery, changes in eating and activity, and changes in mental health. Some of these changes should be reduced, while others should be explored and enhanced.
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Toba, Ange-Lionel, Liam Boire, and Timothy McJunkin. "Integrated Water-Power System Resilience Analysis in a Southeastern Idaho Irrigation District: Minidoka Case Study." Sustainability 13, no. 19 (2021): 10906. http://dx.doi.org/10.3390/su131910906.
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This study investigates the joint water–power system resilience of an irrigation district in southeastern Idaho. Irrigation districts face difficulties in the delivery of water to farmers under drought conditions, during equipment failures, or unplanned infrastructure disruptions. The resilience of interconnected water and power systems can be better analyzed and understood through an integrated approach, using a model that connects the dependencies between the two halves of the system. Using a multi-agent system model capturing both water and power system components, as well as their linkages, we capture the interdependencies of these systems and highlight opportunities for improvement when faced with disruptions. Through simulation scenarios, we examine the system resilience using system performance, quantified as the percentage of met demand of the power and water system, when subjected to drought water year, an unforeseen water demand increase, power outage and dam failure. Scenario results indicate that the effects of low flow years are mostly felt in the power system; unexpected increases in water demand marginally impact irrigation system performance; dams and pumps present vulnerabilities of the system, causing substantial unmet demand during disruptions. Noting the interdependencies between the water–power system halves while leveraging an integrated simulation allows for an insightful analysis of the system impacts during disruptions.