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Rozprawy doktorskie na temat „LPC 2148”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Zawawi, Khalid Hashim. "Moesin mediated intracellular signalling in LPS-stimulated differentiated THP-1 cells." Thesis, Boston University, 2004. https://hdl.handle.net/2144/31303.

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Thesis (D.Sc.)--Boston University, Henry M. Goldman School of Dental Medicine, 2004 (Oral Biology).<br>Includes bibliography (leaves 107-151).<br>Lipopolysaccharide (LPS), a glycolipid found in the outer membrane of Gram negative bacteria, induces the secretion of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-a) and interleukin (IL )-1, by monocytes/macrophages. Excessive and uncontrolled secretion of these compounds leads to multiple pathological conditions, such as septic shock. LPS receptors have been shown to be CD14, TLR4 and MD-2. LPS interaction with these rec

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D'AQUILIO, FABIOLA. "Activatory properties of lysophosphatidic acid (LPA) on human THP-1 monocytes." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/932.

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Excessive proliferation as well as the release of proinflammatory mediators from leukocytes represent common phenomena in several important diseases characterized by chronic inflammation such as atherosclerosis, bronchial asthma, and sepsis. In this context, early monocyte proliferation and activation can contribute to the development and progression of inflammatory processes by means of the synthesis and the release of biologically active molecules such as arachidonic acid metabolites, reactive oxygen intermediates (ROI) and nitric oxide (NO). Several evidences identify lysophosphatidic acid

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3

MASSARO, FRANCESCO. "Spectral evolution of the high energy emission from TeV BL Lac Objects." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2007. http://hdl.handle.net/2108/381.

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I Blazar sono una delle più enigmatiche classi tra i Nuclei Galattici Attivi (AGN). Secondo lo schema unificato degli AGN queste sorgenti sono interpretate come radio-sorgenti con un getto relativistico che è allineato lungo la linea di vista. I Blazar si dividono principalmente in due classi: la prima, costituita dagli oggetti di tipo BL Lac, con spettri in banda visibile privi di righe, e la seconda composta dai quasar con spettro radio piatto (FSRQ) che invece presentano righe di emissione. L’emissione dei Blazar si estende dalla banda radio fino alla banda dei raggi gamma di più alta

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GROSSI, GIULIO CORNELIO. "Measurement of the Z⁰ forward-backward asymmetry in muon pairs with the ATLAS experiment at LHC." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2014. http://hdl.handle.net/2108/202057.

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SABATINO, GIOVANNI. "Charmonium production at LHCb: measurement of the psi' to J/psi production ratio with the first data." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1244.

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L'esperimento LHCb, installato presso i laboratori del CERN, sfrutta le collisioni protone-protone prodotte da LHC con energia nel sistema del centro di massa fino a 14 TeV. LHCb permetterà di fare misure di violazione di CP mediante decadimenti dei mesoni B. Inoltre permetterà di misurare i branching ratio dei decadimenti rari dei mesoni B. La fisica del sapore è un canale privilegiato per osservare indirettamente eventuali effetti di Nuova Fisica, nonché per comprendere meglio alcuni meccanismi di produzione non ancora del tutto chiari. Nella tesi viene discussa la teoria dell'adroproduzion

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SOLFAROLI, CAMILLOCCI ELENA. "The ATLAS muon trigger detector in the barrel: performance simulation and cosmic ray tests." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2006. http://hdl.handle.net/2108/202629.

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Il Large Hadron Collider (LHC) è l’acceleratore per collisioni di ioni e protoni attualmente in costruzione al CERN di Ginevra. Questa macchina permetterà di raggiungere un’elevata energia nel centro di massa (14 TeV per collisioni protone-protone), dando la possibilità di produrre particelle con masse fino all’ordine del TeV. ATLAS è uno degli esperimenti di LHC. Una delle principali caratteristiche del rivelatore di ATLAS è di avere uno spettrometro per muoni in aria, che opera come un rivelatore a sé stante. Nel barrel il trigger di primo livello dei muoni è fornito dalle camere RPC (Resis

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RACIOPPI, ANTONIO. "Anomalies, U(1)' and the MSSM." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/905.

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Questa Tesi analizza un'estensione del MSSM tramite l'aggiunta di un multipletto vettoriale abeliano anomalo e contiene alcuni risultati originali riguar- danti la fenomenologia di uno $Z'$ anomalo. La parte di rassegna presenta un'introduzione sul MSSM e le sue caratteristiche principali, una discussione sulle anomalie chirali e come cancellarle nel Modello Standard e tramite il meccanismo di Green-Schwarz. Quindi, vengono presentati i risultati originali. Costruiamo la Lagrangiana per la ``Minimal Anomalous U(1)'Extension of the MSSM'', dove le anomalie sono cancellate con il meccani

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BERTUCCI, PIERFRANCESCO. "Valutazione dell’accumulo corporeo totale di ferro in pazienti β-talassemici". Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2008. http://hdl.handle.net/2108/584.

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β-Thalassemia represents a common single-gene disorder characterised by a defective production of the globin β-chains, which form the haemoglobin molecule. Defective haemoglobin generates a chronic anaemic state in affected patients during the first decade of life, which leds to a progressive accumulation of iron in body tissues, due to recurrent emotransfusional therapy. Overload of iron in endocrine glands, myocardial tissue and liver represents the most evident complication in patients affected by β-thalassemia maior. Measurement of the iron concentration in a liver-biopsy specimen (LIC) by

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9

Portales, Maria. "Implementation of the IEEE 802.11a MAC layer in C language." Thesis, Linköping University, Department of Electrical Engineering, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2144.

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<p>There are several standards for wireless communication. People that are involved in computers and networking recognize names like Bluetooth, HiperLAN and IEEE 802.11. The last one was standardized in 1997 [2,6]and has begun to reach acceptance as a solid ground for wireless networking. A fundamental part of an IEEE 802.11 node is the Medium Access Controller, or MAC. It establishes and controls communication with other nodes, using a physical layer unit. </p><p>The work has been carried out as final project at Linkopings Universitet, it has been about the improvement of the functions of MAC

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Tang, Yinian. "Validation of NG2-creER transgenic mice in demyelination models in studying multiple sclerosis." Thesis, 2020. https://hdl.handle.net/2144/41219.

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MS is an autoimmune neurodegenerative disease that attacks myelin, a protective sheath that covers neurons within our bodies, which may lead to numbness, tremors, issues with vision, dizziness and more. When researching the efficacy of a therapeutic in neurodegenerative diseases such as multiple sclerosis, it is crucial that the in-vivo model selected for testing allows complete and accurate data collection. Several models attempt to replicate conditions of disease, in which myelin levels have been deliberately reduced in order to study its regrowth. These models (Cuprizone and LPC injection)

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Long, Brian Alexander. "WWW production at the LHC." Thesis, 2016. https://hdl.handle.net/2144/17737.

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In 2012 a resonance with a mass of 125 GeV resembling the elusive Higgs boson was discovered simultaneously by the ATLAS and CMS experiments using data collected from the Large Hadron Collider (LHC) at CERN. Its observation finally confirms the mechanism for Spontaneous Electroweak Symmetry Breaking (EWSB) necessary for describing the mass structure of the electroweak (EW) gauge bosons. In 2013, Peter Higgs and Francois Englert were awarded the Nobel Prize in physics for their work in developing this theory of EWSB now referred to as the Higgs mechanism. The explanation for EWSB is often r

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12

Ceccarelli, Rudy. "Development of Radiation Resistant Pixel Detectors for the Luminosity Frontier and Measurement of the Higgs Boson Production via Vector Boson Fusion with the CMS Experiment at the LHC." Doctoral thesis, 2022. http://hdl.handle.net/2158/1264218.

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The Large Hadron Collider (LHC) is the largest circular accelerator ever build, allowing collisions at a center-of-mass energy of 13 TeV. The Phase-2 of the LHC, known as High Luminosity LHC (HL-LHC), is going to start in 2027. With HL-LHC, the Compact Muon Solenoid (CMS) experiment will gather an integrated luminosity up to 4000 fb^{-1} in 10 years, making it possible to study rare events of the Standard Model (SM) or to search for processes beyond it. The CMS experiment will be upgraded between 2025 and 2027 to cope with the higher luminosity: especially in the regions near the coll

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Kopp, Charles. "Cholinergic modulation of excitatory synapses of the ACC and LPFC." Thesis, 2017. https://hdl.handle.net/2144/23826.

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Acetylcholine modulates neuronal activity in the brain with different responses in activity depending on the region of the brain. Our study was focused on the cholinergic modulation of excitatory synaptic transmission in the monkey anterior cingulate cortex (ACC) and lateral prefrontal cortex (LPFC), with specific focus on the effects of carbachol, a cholinergic agonist, on spontaneous excitatory postsynaptic currents (sEPSCs) and on the expression the muscarinic cholinergic type II (M2) receptor in these regions. We used electrophysiology to analyze the effects of carbachol on sEPSC of layer

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Ellis, Kathryn Marie. "The institute for sex, intimacy and occupational therapy, LLC, program evaluation." Thesis, 2019. https://hdl.handle.net/2144/36924.

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Sexuality and intimacy occupations are often considered valued life occupations by individuals and communities and can contribute to quality of life and relationship satisfaction (Diamond & Huebner, 2012; McGrath & Lynch, 2014; Sakellariou & Algado, 2006; Smith et al., 2011). Sexuality and intimacy occupations have the potential to play either enriching or detrimental roles in individuals lived experiences, which supports the notion that healthcare providers must be prepared to address these topics in practice (Collins et al., 2017; Deering et al., 2014; Diamond & Huebner, 2012; Espelage, Ba

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15

Richardson, Clint Allan. "A search for heavy fermionic top quark partners with charge 5/3 decaying to a pair of same-sign leptons with the CMS experiment." Thesis, 2017. https://hdl.handle.net/2144/27478.

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In the millennia of recorded human knowledge, no model for describing the workings of Nature is as elegant or complete as the Standard Model of Particle Physics (SM). However, the SM has several open questions and there exist multiple phenomena that it cannot explain. A pressing question is related to the mass of the Higgs boson, whose value the SM has no natural way of explaining, relying instead on the fine tuning of parameters to one part in 10^{28}. Many extensions of the SM propose new interactions and particles which solve this problem. A particularly common theme is that of new partners

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16

Alasiri, Mansour. "The involvement of KAV001 in inhibition of LPS/P. gingivalis-induced cytokines." Thesis, 2019. https://hdl.handle.net/2144/37030.

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TNF-a is an important cytokine mediator of inflammation which suggests that inhibition of TNF-a activity may provide potential for clinical application. Recent data indicated that treatment of both human and mouse cells with Kavain significantly modulates P. gingivalis- and LPS-induced TNF-α expression. In order to obtain a selective analog with optimized biological activity and structural physico-chemical properties of Kavain, Kavain analogs were designed and synthesized and found one Kavain analogue (named Kav001) that is similar to Kavain but soluble and does not induce a significant toxici

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17

Fantasia, Cory. "Search for exotic particles decaying into WZ boson pairs at the CMS experiment." Thesis, 2014. https://hdl.handle.net/2144/14296.

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The Standard Model (SM) is the theoretical framework that describes the state of the art in particle physics. It has been extremely successful at describing the particles and forces observed in nature. However, the theory is known to be incomplete. Among other things, it cannot explain dark matter, the dynamics of electroweak symmetry breaking, neutrino masses, nor how gravity is to be incorporated into its framework. A popular extension of the SM introduces a new particle similar to a W boson, typically called a W' boson. Other classes of theories, such as technicolor, offer alternati

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18

Rankin, Dylan Sheldon. "Search for heavy resonances decaying to a top quark and a bottom quark in proton-proton collisions at 13 TeV with the CMS experiment." Thesis, 2018. https://hdl.handle.net/2144/33188.

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Searches are presented for narrow heavy resonances decaying to a top quark and a bottom quark using data collected by the CMS experiment at a center-of-mass energy of 13 TeV. Final states that include a single lepton (electron, muon), multiple jets, and missing transverse momentum are analyzed. No evidence is found for the production of a W' boson, and the production of right-handed W' bosons is excluded at 95% confidence level for masses up to 3.6 TeV depending on the scenario considered. Exclusion limits for W' bosons are also presented as a function of their coupling strength to left- and r

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19

TOMMASINI, DAMIANO. "QCD effects on Higgs Boson production and decay at Hadron colliders." Doctoral thesis, 2012. http://hdl.handle.net/2158/615374.

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Mariani, Saverio. "Fixed-target physics with the LHCb experiment at CERN." Doctoral thesis, 2022. http://hdl.handle.net/2158/1264217.

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Owing to its detector geometry covering the forward direction and its excellent track reconstruction and particle identification performance, the LHCb experiment at CERN started in 2015 a pioneering study of beam-gas collisions by injecting noble gases in the LHC accelerator. In this thesis, my contributions to this physics programme, addressing the demand for extending the physics reach of the LHC complex stressed in the 2020 European Strategy for Particle Physics Update, are presented. Using a sample of proton-helium collisions collected in 2016, I performed the measurement of the non-

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21

Lawson, Philip Daniel. "Measurement of the W charge asymmetry in production with jets using 5 inverse-femtobarns of data measured at sqrt(s)=7 TeV with CMS." Thesis, 2014. https://hdl.handle.net/2144/14290.

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A measurement of the electron charge asymmetry in p+→W production in association with jets at sqrt{s}=7 TeV is presented. The dataset corresponds to an integrated luminosity of L=5fb^-1 recorded by the CMS detector in proton-proton collisions at the LHC. The sample represents a large increase in statistical precision with respect to previous CMS results and describes a first study of charge asymmetry measured in p+p→W+1 jet events. Full comparisons to previous results and theoretical predictions are provided and recommendations for extending the analysis to produce valuable input for future

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Kruskal, Michael. "A search for dark matter with bottom quarks." Thesis, 2016. https://hdl.handle.net/2144/14522.

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Despite making up over 80% of the matter in the universe, very little is known about dark matter. Its only well-established property is that it interacts gravitationally, but does not interact with ordinary matter through any of the other known forces. Specific details such as the number of dark matter particles, their quantum properties, and their interactions remain elusive and are only loosely constrained by experiments. In this dissertation I describe a novel search for a particular type of dark matter that couples preferentially to heavy quarks, using LHC proton-proton collisions at AT

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Bernard, Clare Sullivan. "Standard model and exotic physics with the top quark at ATLAS." Thesis, 2014. https://hdl.handle.net/2144/15386.

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The top quark is the most massive fundamental particle in the Standard Model of particle physics. Only experimentally observed in 1995, it can be used as a precise test of Standard Model predictions, and it could lend insight to the problem of what lies beyond the Standard Model. This thesis presents a measurement of top-quark pair production using data collected at a center-of-mass energy √s=7 TeV in 2011, and a search for production of vector-like quarks using data collected at √s=8 TeV in 2012. Both datasets were recorded by the ATLAS detector, a multipurpose proton-proton collider located

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BROCCOLO, GIUSEPPE. "Study of prompt J/psi production in LHC proton-proton collisions atsqroot(s) = 10 TeV in the J/psi e+e− decay channel." Doctoral thesis, 2010. http://hdl.handle.net/2158/442858.

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GORI, VALENTINA. "Search for a high mass Higgs-like boson produced via Vector Boson Fusion, in the decay channel H -> ZZ -> llqq (l=e, mu) with the CMS detector." Doctoral thesis, 2015. http://hdl.handle.net/2158/1020428.

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Nella tesi si presenta il lavoro di analisi condotto nell'ambito dell'esperimento CMS ad LHC per la ricerca di un bosone di Higgs ad alta massa, prodotto con il meccanismo della Vector Boson Fusion e con decadimento in due bosoni Z, che a loro volta decadono in una coppia di leptoni e una coppia di quark. I risultati sono interpretati sia nell'ambito del Modello Standard che nello scenario di Electroweak singlet. Si sono usate tecniche multivariate (machine learning).

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Rajanbabu, Venugopal, and 瑞江. "Antimicrobial peptide tilapia hepcidin (TH) 2-3 mediated modulation of immune responses in LPS stimulated mouse macrophages, and TH1-5 mediated antiviral function against IPNV in CHSE-214 cells." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/14645024696611861951.

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博士<br>國立中興大學<br>生物科技學研究所<br>99<br>Antimicrobial peptides (AMPs) play a vital role in non-specific innate host defense mechanism against various pathogens. In addition to direct antimicrobial function, they are also involved in the modulation of immune responsive genes against pathogen infection. Hepcidin is one of the important AMPs known for its antimicrobial and iron homeostasis function. The tilapia hepcidin (TH) 2-3 and TH1-5 were recently cloned in tilapia fish. The expression of TH2-3 has been shown to be up-regulated by the bacterial endotoxin lipopolysachcharride (LPS), and the TH1-5 i

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VILIANI, LORENZO. "Measurement of the Higgs boson properties and search for new resonances using W+W- decays with the CMS detector." Doctoral thesis, 2017. http://hdl.handle.net/2158/1086391.

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The Higgs mechanism is an essential element of the Standard Model (SM), explaining the origin of mass and playing a key role in the physics of electroweak symmetry breaking. A suitable Higgs boson candidate, predicted by the Higgs mechanism, was found with a mass of 125 GeV by the ATLAS and CMS experiments in the first run of the CERN Large Hadron Collider (LHC). After the discovery, the accurate measurement of the Higgs boson properties has become one of the main goals of the LHC. The Higgs sector could in fact be more entangled with respect to what discovered so far and Beyond the Standar

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GONZI, SANDRO. "Study of gamma + jets data with the CMS detector in pp collisions at sqrt(s) = 8 TeV." Doctoral thesis, 2014. http://hdl.handle.net/2158/839694.

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The characterization of the production process of prompt photons γ in association with hadronic jets (γ + jets process) at the Large Hadron Collider (LHC), is one of the goals in physics analyses at the Compact Muon Solenoid (CMS) experiment. This channel provides a way of directly probing the hard scattering process and it is directly sensitive to the gluonic content of the proton. This process is also the starting point for the study of many Standard Model signatures, and constitutes a background for important searches, such as H->γγ, or SUSY and extra-dimensions with energetic photons in th

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Oliveira, Rita de Castro Sousa. "The book of birds in Portuguese scriptoria: preservation and access." Doctoral thesis, 2016. http://hdl.handle.net/10362/21481.

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In this thesis, the Books of Birds from Hugh of Fouilloy produced in the Portuguese monasteries of São Mamede of Lorvão, Santa Maria of Alcobaça and Santa Cruz of Coimbra, were studied for the first time through an interdisciplinary and holistic approach. This investigation opened doors to a customized methodology for the study of manuscript circulation, by converging their history, codicology, iconography, colour – both molecular and symbolic – text analysis and conservation state. This allowed proposing new chronologies and correlations between each copy. Santa Cruz still lacked a comprehe

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FROSALI, SIMONE. "Measurement of sigma(Z/gamma* + >= n jets) in the electronic channel with the CMS detector." Doctoral thesis, 2012. http://hdl.handle.net/2158/630095.

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